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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HAND1

Z-value: 0.99

Motif logo

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.2 heart and neural crest derivatives expressed 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_153900655_153900951HAND1429790.133708-0.732.6e-02Click!
chr5_153856378_153856529HAND113710.4193290.722.8e-02Click!
chr5_153853814_153853984HAND139250.2134880.551.2e-01Click!
chr5_153852765_153852916HAND149840.1970800.531.5e-01Click!
chr5_153845026_153845177HAND1127230.160774-0.491.8e-01Click!

Activity of the HAND1 motif across conditions

Conditions sorted by the z-value of the HAND1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_97009046_97009425 0.40 NCAPH
 non-SMC condensin I complex, subunit H
 7679
 0.15
chr17_37252182_37252943 0.38 PLXDC1
 plexin domain containing 1
 11178
 0.15
chr13_114892713_114893126 0.37 RASA3
 RAS p21 protein activator 3
 5108
 0.24
chr11_4111133_4111394 0.36 RRM1
 ribonucleotide reductase M1
 4776
 0.22
chr14_67948872_67949023 0.34 TMEM229B
 transmembrane protein 229B
 6502
 0.18
chrX_47482564_47483099 0.34 SYN1
 synapsin I
 3579
 0.15
chr4_15769645_15769984 0.34 CD38
 CD38 molecule
 10087
 0.23
chr1_65342372_65342702 0.32 JAK1
 Janus kinase 1
 89650
 0.08
chr1_28296104_28296455 0.31 RP11-460I13.2
9575
 0.13
chr3_33472190_33472341 0.31 UBP1
 upstream binding protein 1 (LBP-1a)
 9237
 0.21
chr8_93029450_93029601 0.31 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 66
 0.98
chr12_104973749_104974059 0.31 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 8722
 0.24
chr2_127418703_127419020 0.31 GYPC
 glycophorin C (Gerbich blood group)
 5101
 0.3
chr5_14439836_14439987 0.31 TRIO
 trio Rho guanine nucleotide exchange factor
 48646
 0.18
chr3_11677644_11677795 0.31 VGLL4
 vestigial like 4 (Drosophila)
 7679
 0.22
chr6_126142988_126143327 0.31 NCOA7-AS1
 NCOA7 antisense RNA 1
 3153
 0.24
chr1_198503645_198504115 0.30 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 5924
 0.32
chr3_113949300_113949543 0.29 ZNF80
 zinc finger protein 80
 7004
 0.18
chr13_40762290_40762441 0.29 ENSG00000207458
 .
 38599
 0.22
chr1_27076332_27076532 0.28 ENSG00000266138
 .
 13683
 0.13
chr12_68176752_68176973 0.28 RP11-335O4.3
112163
 0.07
chr16_67836589_67836775 0.28 RANBP10
 RAN binding protein 10
 3778
 0.12
chr19_2775327_2775584 0.28 SGTA
 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
 4676
 0.12
chr1_19768716_19768889 0.28 ENSG00000240490
 .
 17924
 0.15
chr2_136578827_136578978 0.28 AC011893.3
1141
 0.45
chr1_90064313_90064509 0.28 LRRC8B
 leucine rich repeat containing 8 family, member B
 30611
 0.14
chr1_40137074_40137225 0.28 NT5C1A
 5'-nucleotidase, cytosolic IA
 561
 0.66
chr1_221957617_221957791 0.27 DUSP10
 dual specificity phosphatase 10
 42186
 0.19
chr1_221508301_221508621 0.27 DUSP10
 dual specificity phosphatase 10
 402341
 0.01
chr6_112044961_112045268 0.27 FYN
 FYN oncogene related to SRC, FGR, YES
 3849
 0.3
chr10_74923079_74923230 0.27 ECD
 ecdysoneless homolog (Drosophila)
 4663
 0.12
chr6_109036108_109036376 0.27 FOXO3
 forkhead box O3
 58693
 0.15
chr11_128396911_128397217 0.26 RP11-1007G5.2
1027
 0.59
chr14_98675980_98676131 0.26 ENSG00000222066
 .
 122032
 0.06
chr10_121044351_121044502 0.26 RP11-79M19.2
51268
 0.11
chr17_34040072_34040441 0.26 RASL10B
 RAS-like, family 10, member B
 18412
 0.11
chr7_8167446_8167940 0.26 AC006042.6
14038
 0.21
chr3_16944411_16944593 0.26 PLCL2
 phospholipase C-like 2
 18050
 0.23
chr2_47170482_47170698 0.25 MCFD2
 multiple coagulation factor deficiency 2
 1596
 0.28
chr11_104670330_104670481 0.25 CASP12
 caspase 12 (gene/pseudogene)
 98736
 0.08
chr13_110383641_110384047 0.25 LINC00676
 long intergenic non-protein coding RNA 676
 3215
 0.35
chr2_98582630_98582781 0.25 TMEM131
 transmembrane protein 131
 29649
 0.2
chr10_63840836_63841344 0.25 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 32120
 0.19
chr7_132116532_132116686 0.25 AC011625.1
79516
 0.11
chr17_17084049_17084292 0.25 MPRIP
 myosin phosphatase Rho interacting protein
 1298
 0.29
chr19_654179_654330 0.25 RNF126
 ring finger protein 126
 7148
 0.09
chr1_229889719_229889932 0.24 URB2
 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
 103231
 0.07
chr2_38925814_38925965 0.24 GALM
 galactose mutarotase (aldose 1-epimerase)
 17452
 0.16
chr9_123679203_123679400 0.24 TRAF1
 TNF receptor-associated factor 1
 2451
 0.31
chr11_60755747_60755977 0.24 ENSG00000207153
 .
 3223
 0.16
chr1_54744952_54745103 0.24 RP5-997D24.3
6051
 0.18
chr3_187897306_187897937 0.23 AC022498.1
 Uncharacterized protein
 1290
 0.5
chrX_44125263_44125482 0.23 EFHC2
 EF-hand domain (C-terminal) containing 2
 77546
 0.11
chr14_61984119_61984270 0.23 RP11-47I22.4
11652
 0.2
chr7_2178117_2178407 0.23 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 29026
 0.21
chr3_134385868_134386019 0.23 KY
 kyphoscoliosis peptidase
 16079
 0.23
chr14_92341016_92341177 0.23 FBLN5
 fibulin 5
 3290
 0.26
chr7_640540_641424 0.23 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
 1338
 0.36
chrX_19778652_19778939 0.23 SH3KBP1
 SH3-domain kinase binding protein 1
 12974
 0.29
chr4_73932257_73932427 0.23 COX18
 COX18 cytochrome C oxidase assembly factor
 3067
 0.32
chr2_30488933_30489313 0.23 LBH
 limb bud and heart development
 34077
 0.19
chr9_131832251_131832515 0.23 DOLPP1
 dolichyldiphosphatase 1
 10996
 0.11
chr8_125649609_125649792 0.23 RP11-532M24.1
57828
 0.12
chr2_99323973_99324148 0.23 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 19099
 0.21
chr2_175644427_175644584 0.23 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
 15305
 0.23
chr1_207098582_207098736 0.23 FAIM3
 Fas apoptotic inhibitory molecule 3
 2067
 0.25
chr3_10284470_10284734 0.22 TATDN2
 TatD DNase domain containing 2
 5105
 0.14
chr5_110590081_110590232 0.22 AC010468.2
15631
 0.2
chr6_12163632_12164063 0.22 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 37868
 0.22
chr2_45029072_45029470 0.22 ENSG00000252896
 .
 20002
 0.27
chr3_15359672_15359823 0.22 ENSG00000238891
 .
 1620
 0.31
chr2_109790847_109791252 0.22 ENSG00000264934
 .
 33005
 0.2
chr16_16135222_16135434 0.22 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 31615
 0.19
chr1_206752443_206752919 0.22 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 22188
 0.14
chr2_12644304_12644548 0.22 ENSG00000207183
 .
 92799
 0.09
chr8_12860265_12860557 0.22 ENSG00000206996
 .
 41448
 0.16
chr17_26134829_26135084 0.22 NOS2
 nitric oxide synthase 2, inducible
 7431
 0.21
chr9_132033309_132033483 0.22 ENSG00000220992
 .
 40400
 0.13
chr17_75452925_75453139 0.22 SEPT9
 septin 9
 584
 0.7
chr11_128290296_128290447 0.21 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 84918
 0.1
chr14_104383228_104383519 0.21 C14orf2
 chromosome 14 open reading frame 2
 4458
 0.17
chr3_15578936_15579113 0.21 COLQ
 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
 15766
 0.14
chr4_90600499_90600650 0.21 RP11-115D19.1
2089
 0.47
chr17_14106066_14106394 0.21 AC005224.2
7575
 0.21
chr11_68272006_68272464 0.21 ENSG00000222339
 .
 884
 0.48
chr2_144302669_144302857 0.21 RP11-570L15.2
26911
 0.19
chr10_15212970_15213280 0.21 NMT2
 N-myristoyltransferase 2
 2433
 0.32
chr3_38539403_38539554 0.21 EXOG
 endo/exonuclease (5'-3'), endonuclease G-like
 1506
 0.38
chrX_78420820_78421003 0.21 GPR174
 G protein-coupled receptor 174
 5558
 0.35
chr18_2702393_2702544 0.21 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
 46582
 0.11
chrX_19766528_19766693 0.21 SH3KBP1
 SH3-domain kinase binding protein 1
 789
 0.77
chr3_177661794_177662251 0.21 ENSG00000199858
 .
 63545
 0.15
chr2_190149930_190150081 0.21 ENSG00000266817
 .
 26482
 0.23
chr4_48344741_48344971 0.21 SLAIN2
 SLAIN motif family, member 2
 1517
 0.49
chr11_65870833_65870984 0.20 PACS1
 phosphofurin acidic cluster sorting protein 1
 2674
 0.17
chr3_119732053_119732204 0.20 GSK3B
 glycogen synthase kinase 3 beta
 80385
 0.09
chr17_75960444_75960595 0.20 TNRC6C
 trinucleotide repeat containing 6C
 39730
 0.14
chr12_52654824_52655351 0.20 KRT121P
 keratin 121 pseudogene
 2436
 0.15
chr1_32667214_32667874 0.20 CCDC28B
 coiled-coil domain containing 28B
 1310
 0.22
chr11_69519758_69519936 0.20 FGF19
 fibroblast growth factor 19
 437
 0.84
chr8_71580114_71580327 0.20 LACTB2
 lactamase, beta 2
 1172
 0.34
chr3_16865405_16865955 0.20 PLCL2
 phospholipase C-like 2
 60772
 0.14
chr22_37226429_37226580 0.20 PVALB
 parvalbumin
 10981
 0.13
chr2_144301655_144301806 0.20 RP11-570L15.2
27944
 0.19
chr15_65574741_65574985 0.20 ENSG00000206903
 .
 3066
 0.17
chr1_167604982_167605729 0.20 RP3-455J7.4
5444
 0.21
chr9_139298829_139298980 0.20 SDCCAG3
 serologically defined colon cancer antigen 3
 2733
 0.14
chr5_34570275_34570426 0.19 RAI14
 retinoic acid induced 14
 85992
 0.09
chr10_35808142_35808293 0.19 GJD4
 gap junction protein, delta 4, 40.1kDa
 86121
 0.08
chr10_127824965_127825297 0.19 ENSG00000222740
 .
 9020
 0.29
chr14_98677293_98677464 0.19 ENSG00000222066
 .
 120709
 0.06
chr7_47791048_47791199 0.19 LINC00525
 long intergenic non-protein coding RNA 525
 9951
 0.23
chr10_111776497_111776648 0.19 ADD3
 adducin 3 (gamma)
 8850
 0.21
chr10_11358280_11358431 0.19 CELF2-AS1
 CELF2 antisense RNA 1
 3492
 0.36
chr4_6919752_6920098 0.19 TBC1D14
 TBC1 domain family, member 14
 7950
 0.19
chr19_7581365_7581909 0.19 ZNF358
 zinc finger protein 358
 633
 0.51
chr20_39775264_39775450 0.19 RP1-1J6.2
8714
 0.2
chr12_104977859_104978010 0.19 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 4692
 0.26
chr9_18385263_18385414 0.19 ADAMTSL1
 ADAMTS-like 1
 88554
 0.1
chr12_111893200_111893523 0.19 ATXN2
 ataxin 2
 555
 0.76
chr14_62543804_62543955 0.19 RP11-355I22.7
33714
 0.23
chr15_101303814_101303965 0.19 ALDH1A3
 aldehyde dehydrogenase 1 family, member A3
 114030
 0.05
chr16_29988360_29988511 0.19 TAOK2
 TAO kinase 2
 2833
 0.11
chr6_37471487_37471725 0.19 CCDC167
 coiled-coil domain containing 167
 3908
 0.25
chr2_42332803_42333174 0.18 PKDCC
 protein kinase domain containing, cytoplasmic
 57828
 0.11
chr10_105208792_105209256 0.18 RP11-225H22.7
929
 0.37
chr8_8704312_8704638 0.18 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 46680
 0.14
chr14_98909850_98910089 0.18 ENSG00000241757
 .
 91968
 0.09
chr12_12016346_12017014 0.18 ETV6
 ets variant 6
 22191
 0.26
chr7_134512686_134512837 0.18 CALD1
 caldesmon 1
 15874
 0.27
chr3_43359417_43359828 0.18 ENSG00000241939
 .
 3179
 0.23
chr11_118567796_118568096 0.18 ENSG00000207462
 .
 5105
 0.14
chr1_32730988_32731377 0.18 LCK
 lymphocyte-specific protein tyrosine kinase
 8532
 0.09
chr9_137285314_137285572 0.18 RXRA
 retinoid X receptor, alpha
 12985
 0.22
chr7_105537147_105537368 0.18 ATXN7L1
 ataxin 7-like 1
 20207
 0.25
chr15_48931540_48931691 0.18 FBN1
 fibrillin 1
 6303
 0.29
chr14_72908650_72908927 0.18 RGS6
 regulator of G-protein signaling 6
 12440
 0.31
chr15_70196429_70196590 0.18 ENSG00000215958
 .
 118666
 0.06
chr8_117744312_117744463 0.18 EIF3H
 eukaryotic translation initiation factor 3, subunit H
 23636
 0.2
chr19_44436594_44436745 0.18 ZNF45
 zinc finger protein 45
 2742
 0.17
chr10_112431690_112431897 0.18 RBM20
 RNA binding motif protein 20
 27638
 0.14
chr20_55036334_55036485 0.18 ENSG00000212084
 .
 996
 0.44
chr7_24600789_24600940 0.18 MPP6
 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
 12023
 0.24
chr15_42068094_42068245 0.18 MAPKBP1
 mitogen-activated protein kinase binding protein 1
 1269
 0.33
chr15_100782496_100782647 0.18 ADAMTS17
 ADAM metallopeptidase with thrombospondin type 1 motif, 17
 98770
 0.07
chr2_143898363_143898928 0.18 ARHGAP15
 Rho GTPase activating protein 15
 11762
 0.25
chr11_587585_588264 0.18 PHRF1
 PHD and ring finger domains 1
 11403
 0.07
chr1_25800396_25800562 0.18 TMEM57
 transmembrane protein 57
 43068
 0.11
chr2_225810689_225810885 0.18 DOCK10
 dedicator of cytokinesis 10
 995
 0.69
chr12_76945362_76945546 0.18 OSBPL8
 oxysterol binding protein-like 8
 7830
 0.32
chr6_45705684_45705835 0.18 ENSG00000252738
 .
 91918
 0.09
chrY_22739941_22740092 0.18 EIF1AY
 eukaryotic translation initiation factor 1A, Y-linked
 2336
 0.46
chrX_64901581_64901971 0.18 MSN
 moesin
 14239
 0.29
chr1_90126896_90127047 0.18 LRRC8C
 leucine rich repeat containing 8 family, member C
 28340
 0.15
chr5_171579294_171579519 0.18 STK10
 serine/threonine kinase 10
 35984
 0.15
chr8_126946234_126946440 0.18 ENSG00000206695
 .
 33142
 0.25
chr2_28624680_28624911 0.18 RP11-373D23.2
5113
 0.18
chr14_22972883_22973034 0.18 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 16787
 0.09
chr17_64371368_64371623 0.18 ENSG00000244044
 .
 11348
 0.22
chr11_75040450_75040782 0.17 ENSG00000199090
 .
 5614
 0.16
chr2_235388644_235388795 0.17 ARL4C
 ADP-ribosylation factor-like 4C
 16525
 0.3
chr1_161167348_161167499 0.17 ADAMTS4
 ADAM metallopeptidase with thrombospondin type 1 motif, 4
 1420
 0.16
chr1_198713615_198713766 0.17 RP11-553K8.5
77500
 0.1
chr4_122087583_122087734 0.17 TNIP3
 TNFAIP3 interacting protein 3
 2163
 0.36
chr22_24868016_24868188 0.17 UPB1
 ureidopropionase, beta
 4896
 0.18
chr14_103249481_103249632 0.17 TRAF3
 TNF receptor-associated factor 3
 5601
 0.2
chrX_100877410_100877579 0.17 ARMCX3
 armadillo repeat containing, X-linked 3
 293
 0.8
chr14_99647460_99647611 0.17 AL162151.4
22782
 0.23
chr18_9090620_9090967 0.17 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
 11835
 0.18
chr12_15791050_15791201 0.17 EPS8
 epidermal growth factor receptor pathway substrate 8
 24083
 0.2
chr10_104022395_104022570 0.17 ENSG00000251989
 .
 1495
 0.33
chr20_44509042_44509193 0.17 ZSWIM1
 zinc finger, SWIM-type containing 1
 749
 0.41
chr20_2722949_2723333 0.17 EBF4
 early B-cell factor 4
 36254
 0.09
chr20_18523568_18523719 0.17 SEC23B
 Sec23 homolog B (S. cerevisiae)
 631
 0.61
chr5_133478997_133479191 0.17 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 611
 0.75
chr4_10621970_10622121 0.17 CLNK
 cytokine-dependent hematopoietic cell linker
 36140
 0.23
chr1_233416939_233417108 0.17 PCNXL2
 pecanex-like 2 (Drosophila)
 14436
 0.26
chrX_68051807_68052101 0.17 EFNB1
 ephrin-B1
 3114
 0.39
chr4_108978798_108979031 0.17 HADH
 hydroxyacyl-CoA dehydrogenase
 53123
 0.13
chr6_35278431_35279308 0.17 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 1354
 0.42
chr9_92043695_92043846 0.17 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 7608
 0.26
chr15_33321925_33322076 0.17 FMN1
 formin 1
 38085
 0.18
chr6_24893842_24894069 0.17 FAM65B
 family with sequence similarity 65, member B
 16372
 0.2
chr1_167472608_167472887 0.17 CD247
 CD247 molecule
 15028
 0.19
chr2_113938283_113938445 0.17 AC016683.5
5427
 0.15
chr5_130613594_130613745 0.17 CDC42SE2
 CDC42 small effector 2
 13876
 0.28
chr17_42085806_42085957 0.17 NAGS
 N-acetylglutamate synthase
 3756
 0.12
chr1_224570147_224570348 0.16 ENSG00000266618
 .
 15766
 0.14
chr1_109048430_109048671 0.16 FAM102B
 family with sequence similarity 102, member B
 54161
 0.13
chr19_8676942_8677296 0.16 ADAMTS10
 ADAM metallopeptidase with thrombospondin type 1 motif, 10
 1534
 0.33
chr6_139467698_139467849 0.16 HECA
 headcase homolog (Drosophila)
 11524
 0.25
chr18_36157629_36157780 0.16 ENSG00000222704
 .
 438604
 0.01
chr14_69950322_69950473 0.16 PLEKHD1
 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
 1074
 0.6
chr15_66152500_66152651 0.16 RAB11A
 RAB11A, member RAS oncogene family
 9219
 0.19
chr1_52258333_52258484 0.16 RP4-657D16.3
1229
 0.38
chr9_123665604_123665920 0.16 TRAF1
 TNF receptor-associated factor 1
 11088
 0.19
chr6_156342570_156342721 0.16 ENSG00000221456
 .
 74714
 0.13
chr14_71276715_71276967 0.16 MAP3K9
 mitogen-activated protein kinase kinase kinase 9
 590
 0.84
chr1_157083117_157083268 0.16 ETV3L
 ets variant 3-like
 13592
 0.19
chr20_25022537_25022783 0.16 ACSS1
 acyl-CoA synthetase short-chain family member 1
 9321
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.2 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0051892 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:2000351 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.0 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.3 GO:0051806 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.0 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0051194 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.0 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.0 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0002577 regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0042533 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins