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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HBP1

Z-value: 2.35

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
ENSG00000105856.9 HMG-box transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_106807733_106808029HBP115250.4204810.722.8e-02Click!
chr7_106810435_106811179HBP15890.7660240.693.9e-02Click!
chr7_106848899_106849050HBP1126810.201052-0.618.4e-02Click!
chr7_106817414_106817627HBP125510.2950690.608.9e-02Click!
chr7_106873296_106873447HBP1370780.153871-0.608.9e-02Click!

Activity of the HBP1 motif across conditions

Conditions sorted by the z-value of the HBP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_41978332_41978858 1.04 ENSG00000206875
.
7657
0.17
chr16_29679631_29679782 0.96 QPRT
quinolinate phosphoribosyltransferase
5106
0.14
chr17_643839_644304 0.93 FAM57A
family with sequence similarity 57, member A
7706
0.13
chr1_31216034_31216306 0.87 ENSG00000264773
.
4091
0.19
chr19_51713695_51713974 0.86 SIGLEC22P
sialic acid binding Ig-like lectin 22, pseudogene
532
0.62
chr15_89191299_89191585 0.72 ISG20
interferon stimulated exonuclease gene 20kDa
9258
0.17
chr14_94421212_94421558 0.72 ASB2
ankyrin repeat and SOCS box containing 2
232
0.91
chr14_99720519_99720759 0.71 AL109767.1

8646
0.22
chr6_130456767_130457139 0.70 RP11-73O6.3

2388
0.36
chr4_38529612_38529958 0.68 RP11-617D20.1

96411
0.08
chr5_175112211_175112498 0.67 HRH2
histamine receptor H2
3890
0.25
chr19_17981935_17982086 0.66 SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
772
0.51
chr2_68995898_68996135 0.65 ARHGAP25
Rho GTPase activating protein 25
5917
0.26
chr5_39212705_39213008 0.60 FYB
FYN binding protein
6809
0.3
chr22_37696225_37696376 0.59 CYTH4
cytohesin 4
9709
0.17
chr14_61902411_61902624 0.59 PRKCH
protein kinase C, eta
6759
0.27
chr22_37255941_37256092 0.59 NCF4
neutrophil cytosolic factor 4, 40kDa
1014
0.44
chr6_41169070_41169540 0.58 TREML2
triggering receptor expressed on myeloid cells-like 2
373
0.8
chr5_49725654_49725805 0.58 EMB
embigin
1168
0.67
chr7_5573288_5573527 0.58 ACTB
actin, beta
3067
0.16
chr8_27214852_27215342 0.57 PTK2B
protein tyrosine kinase 2 beta
23071
0.19
chr19_17875302_17875453 0.57 FCHO1
FCH domain only 1
1865
0.24
chr1_198602363_198602702 0.55 PTPRC
protein tyrosine phosphatase, receptor type, C
5269
0.27
chr3_71752260_71752853 0.55 EIF4E3
eukaryotic translation initiation factor 4E family member 3
21970
0.2
chr5_169719123_169719274 0.54 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
6033
0.24
chr6_36748367_36748544 0.54 CPNE5
copine V
23269
0.17
chrX_41251596_41251747 0.53 ENSG00000264573
.
46542
0.12
chr11_1881133_1881495 0.53 ENSG00000264493
.
548
0.59
chr14_72064329_72064928 0.53 SIPA1L1
signal-induced proliferation-associated 1 like 1
323
0.94
chr19_37957563_37957802 0.52 ZNF569
zinc finger protein 569
428
0.68
chr11_82461650_82461903 0.52 FAM181B
family with sequence similarity 181, member B
16870
0.25
chr10_11187947_11188252 0.51 CELF2
CUGBP, Elav-like family member 2
18894
0.19
chr11_75521610_75521761 0.51 RP11-535A19.2

928
0.39
chr12_96487410_96487841 0.51 ENSG00000266889
.
8402
0.2
chr14_89822911_89823062 0.51 RP11-356K23.2

1582
0.36
chr19_19029516_19029667 0.51 COPE
coatomer protein complex, subunit epsilon
581
0.47
chr10_126418566_126418777 0.50 FAM53B
family with sequence similarity 53, member B
12868
0.17
chr2_103034112_103034476 0.50 IL18RAP
interleukin 18 receptor accessory protein
855
0.53
chr2_231530189_231530353 0.50 CAB39
calcium binding protein 39
47289
0.13
chr2_61114424_61114612 0.49 REL
v-rel avian reticuloendotheliosis viral oncogene homolog
5727
0.21
chr1_112047360_112047511 0.49 ADORA3
adenosine A3 receptor
1053
0.39
chr4_100743387_100743615 0.49 DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
5498
0.27
chr1_202922580_202922870 0.48 ADIPOR1
adiponectin receptor 1
4688
0.14
chr1_192783354_192783505 0.48 RGS2
regulator of G-protein signaling 2, 24kDa
5258
0.29
chr12_108694238_108694389 0.48 CMKLR1
chemokine-like receptor 1
17381
0.25
chr17_65433675_65433892 0.47 ENSG00000244610
.
19623
0.12
chr20_62529455_62529790 0.47 DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
3087
0.1
chr9_104160335_104160552 0.47 MRPL50
mitochondrial ribosomal protein L50
443
0.6
chr10_8225843_8226238 0.47 GATA3
GATA binding protein 3
129271
0.06
chr14_61814853_61815190 0.47 PRKCH
protein kinase C, eta
412
0.87
chr2_190441780_190441932 0.47 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
3757
0.29
chr10_13203735_13204030 0.47 MCM10
minichromosome maintenance complex component 10
303
0.9
chr1_28525263_28525593 0.47 AL353354.2

1642
0.2
chr11_128359823_128359974 0.47 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
15391
0.24
chr21_35304821_35305087 0.46 LINC00649
long intergenic non-protein coding RNA 649
1436
0.35
chr6_135819174_135819325 0.46 AHI1
Abelson helper integration site 1
335
0.92
chr12_4016384_4016722 0.46 RP11-664D1.1

2167
0.39
chr14_72020524_72020893 0.45 SIPA1L1
signal-induced proliferation-associated 1 like 1
24666
0.25
chr3_151912329_151912486 0.45 MBNL1
muscleblind-like splicing regulator 1
73422
0.11
chr6_90806272_90806423 0.45 ENSG00000222078
.
95122
0.08
chr10_129704503_129704722 0.45 PTPRE
protein tyrosine phosphatase, receptor type, E
713
0.71
chr20_60606558_60606856 0.44 TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
24090
0.16
chr9_100862148_100862401 0.44 TRIM14
tripartite motif containing 14
7431
0.19
chr1_112048866_112049017 0.44 ADORA3
adenosine A3 receptor
2559
0.18
chr15_55687942_55688093 0.44 CCPG1
cell cycle progression 1
2449
0.25
chr10_126409005_126409284 0.44 FAM53B-AS1
FAM53B antisense RNA 1
16391
0.17
chr8_131008324_131008477 0.44 ENSG00000253043
.
8447
0.18
chr2_233952417_233952631 0.44 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
27335
0.17
chr20_48771195_48771346 0.44 TMEM189
transmembrane protein 189
935
0.41
chr20_48330665_48330822 0.44 B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
328
0.89
chr17_48961761_48962194 0.44 TOB1
transducer of ERBB2, 1
16638
0.15
chr22_46406591_46406742 0.44 WNT7B
wingless-type MMTV integration site family, member 7B
33657
0.09
chr11_72122219_72122398 0.44 RP11-7N14.1

548
0.74
chr7_132766131_132766477 0.44 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
496
0.75
chr14_75885514_75885665 0.44 RP11-293M10.6

8804
0.19
chr1_167570221_167570504 0.43 RCSD1
RCSD domain containing 1
28968
0.15
chr2_102975162_102975412 0.43 IL18R1
interleukin 18 receptor 1
2898
0.25
chr19_6814065_6814233 0.43 VAV1
vav 1 guanine nucleotide exchange factor
30020
0.12
chr12_7056002_7056374 0.43 PTPN6
protein tyrosine phosphatase, non-receptor type 6
415
0.56
chr8_133626087_133626238 0.43 LRRC6
leucine rich repeat containing 6
8772
0.26
chr2_43420768_43421081 0.43 ZFP36L2
ZFP36 ring finger protein-like 2
32824
0.19
chr2_213968123_213968274 0.43 IKZF2
IKAROS family zinc finger 2 (Helios)
45155
0.18
chr22_45691647_45691912 0.42 UPK3A
uroplakin 3A
10907
0.18
chr20_57678404_57678555 0.42 SLMO2
slowmo homolog 2 (Drosophila)
60515
0.1
chr16_28998893_28999044 0.42 LAT
linker for activation of T cells
1435
0.21
chr19_43028998_43029229 0.42 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
2861
0.24
chr1_36269442_36269593 0.42 AGO4
argonaute RISC catalytic component 4
4256
0.21
chr1_12211346_12211755 0.42 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
15510
0.15
chr7_104986020_104986245 0.42 ENSG00000201179
.
12895
0.21
chr1_223334220_223334371 0.41 TLR5
toll-like receptor 5
17671
0.27
chr2_169962877_169963145 0.41 AC007556.3

5758
0.24
chr3_152898855_152899006 0.41 ENSG00000265813
.
18876
0.19
chr12_94568357_94568508 0.41 RP11-74K11.2

1748
0.39
chr13_110814474_110814625 0.41 ENSG00000265885
.
64051
0.13
chr2_43358896_43359072 0.41 ENSG00000207087
.
40352
0.19
chr15_85287429_85287580 0.41 ZNF592
zinc finger protein 592
4362
0.16
chr18_74832353_74832701 0.41 MBP
myelin basic protein
7141
0.31
chr1_161720066_161720217 0.41 DUSP12
dual specificity phosphatase 12
581
0.62
chr10_126386807_126387279 0.41 FAM53B-AS1
FAM53B antisense RNA 1
5151
0.23
chr20_37428146_37428423 0.40 PPP1R16B
protein phosphatase 1, regulatory subunit 16B
6064
0.2
chr8_11660962_11661186 0.40 FDFT1
farnesyl-diphosphate farnesyltransferase 1
553
0.58
chr1_28833699_28833856 0.40 SNHG3
small nucleolar RNA host gene 3 (non-protein coding)
101
0.9
chr8_142282279_142282469 0.40 RP11-10J21.3
Uncharacterized protein
17710
0.13
chr7_127750755_127751118 0.40 ENSG00000207588
.
29023
0.19
chr15_63790258_63790858 0.40 USP3
ubiquitin specific peptidase 3
6235
0.25
chr3_10361845_10362277 0.40 SEC13
SEC13 homolog (S. cerevisiae)
664
0.59
chr8_29408826_29408977 0.40 RP4-676L2.1

198214
0.02
chr21_15853954_15854273 0.40 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
64549
0.12
chr2_101919913_101920064 0.40 RNF149
ring finger protein 149
5170
0.18
chr7_150183282_150183433 0.40 GIMAP7
GTPase, IMAP family member 7
28561
0.14
chr12_107765936_107766182 0.40 ENSG00000200897
.
2465
0.37
chr19_42383865_42384105 0.40 CD79A
CD79a molecule, immunoglobulin-associated alpha
2610
0.16
chr11_76156875_76157293 0.40 C11orf30
chromosome 11 open reading frame 30
860
0.59
chrX_77577768_77577919 0.40 CYSLTR1
cysteinyl leukotriene receptor 1
5137
0.34
chr19_14263876_14264027 0.39 LPHN1
latrophilin 1
289
0.82
chr17_79261558_79261764 0.39 SLC38A10
solute carrier family 38, member 10
5597
0.14
chr1_231534326_231534694 0.39 EGLN1
egl-9 family hypoxia-inducible factor 1
26280
0.17
chr1_10752679_10752996 0.39 CASZ1
castor zinc finger 1
47704
0.13
chr6_11381736_11381962 0.39 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
683
0.8
chr18_9648805_9648956 0.39 ENSG00000212572
.
30810
0.14
chr13_52400020_52400448 0.39 RP11-327P2.5

21801
0.17
chr3_182519103_182519254 0.39 ATP11B
ATPase, class VI, type 11B
7887
0.23
chr20_10414036_10414273 0.39 MKKS
McKusick-Kaufman syndrome
716
0.64
chr1_112046484_112046635 0.39 ADORA3
adenosine A3 receptor
177
0.92
chr17_73829744_73829895 0.39 UNC13D
unc-13 homolog D (C. elegans)
3591
0.11
chrX_39179213_39179364 0.39 ENSG00000207122
.
238750
0.02
chr1_160595319_160595764 0.39 SLAMF1
signaling lymphocytic activation molecule family member 1
21270
0.14
chrX_123146711_123147006 0.38 STAG2
stromal antigen 2
49838
0.15
chr15_68376875_68377026 0.38 PIAS1
protein inhibitor of activated STAT, 1
30036
0.21
chr11_68671799_68671950 0.38 IGHMBP2
immunoglobulin mu binding protein 2
509
0.49
chr17_48474042_48474255 0.38 RP1-117B12.4

349
0.64
chr8_42000592_42000772 0.38 RP11-589C21.5

9599
0.17
chr16_3071550_3071912 0.38 TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
1351
0.14
chr8_101817810_101817961 0.38 ENSG00000222795
.
26203
0.15
chr10_71184917_71185134 0.38 TACR2
tachykinin receptor 2
8402
0.2
chr1_40510930_40511132 0.37 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
4477
0.22
chr1_226916534_226916814 0.37 ITPKB
inositol-trisphosphate 3-kinase B
8485
0.23
chr16_84393622_84393773 0.37 ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
8436
0.19
chr17_72749042_72749252 0.37 MIR3615
microRNA 3615
4096
0.11
chr1_247124558_247124714 0.37 AHCTF1
AT hook containing transcription factor 1
29356
0.17
chr1_17440638_17440789 0.37 PADI2
peptidyl arginine deiminase, type II
5217
0.21
chr12_113376827_113377015 0.37 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
656
0.7
chr6_147271355_147271573 0.37 STXBP5-AS1
STXBP5 antisense RNA 1
34443
0.24
chr13_46741812_46742603 0.37 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
447
0.76
chr12_124118437_124118588 0.37 GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
120
0.61
chr1_226229326_226229477 0.37 H3F3A
H3 histone, family 3A
20151
0.15
chr12_27123542_27123693 0.37 RP11-421F16.3

902
0.5
chr6_143024154_143024342 0.37 RP1-67K17.3

45332
0.19
chr2_172098688_172098839 0.37 TLK1
tousled-like kinase 1
10939
0.27
chr1_230204262_230204501 0.37 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
1363
0.51
chr12_15133482_15133676 0.37 PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
7623
0.18
chr3_10282522_10282828 0.37 TATDN2
TatD DNase domain containing 2
7032
0.13
chr3_13111015_13111169 0.37 IQSEC1
IQ motif and Sec7 domain 1
3525
0.36
chr9_82199849_82200000 0.37 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
11320
0.33
chr1_185535841_185536025 0.37 ENSG00000207108
.
63727
0.12
chr4_153770648_153770924 0.36 ENSG00000252375
.
51332
0.13
chr16_10940856_10941092 0.36 TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
28332
0.13
chr17_37124347_37124498 0.36 FBXO47
F-box protein 47
767
0.58
chr16_20952479_20952845 0.36 LYRM1
LYR motif containing 1
40236
0.13
chr1_175160322_175160769 0.36 KIAA0040
KIAA0040
1345
0.55
chr4_154571823_154571974 0.36 RP11-153M7.3

27513
0.18
chr14_99727931_99728208 0.36 AL109767.1

1216
0.51
chr3_150130327_150130573 0.36 TSC22D2
TSC22 domain family, member 2
1654
0.5
chr5_176812352_176812503 0.36 SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
982
0.35
chr14_100524539_100525167 0.36 EVL
Enah/Vasp-like
6762
0.17
chr15_85302679_85303048 0.36 RP11-7M10.2

6510
0.15
chr8_42009241_42009403 0.36 RP11-589C21.5

959
0.41
chr5_150956755_150956963 0.36 FAT2
FAT atypical cadherin 2
8354
0.2
chr2_223530390_223530541 0.36 MOGAT1
monoacylglycerol O-acyltransferase 1
6040
0.2
chr1_224013320_224013471 0.36 TP53BP2
tumor protein p53 binding protein, 2
11365
0.26
chr17_72454115_72454299 0.36 CD300A
CD300a molecule
8348
0.14
chr19_50435466_50435617 0.36 ENSG00000265438
.
780
0.33
chr3_39091907_39092058 0.36 WDR48
WD repeat domain 48
1507
0.39
chr22_37270765_37270922 0.35 NCF4
neutrophil cytosolic factor 4, 40kDa
2664
0.19
chr4_39358480_39358631 0.35 RFC1
replication factor C (activator 1) 1, 145kDa
9414
0.16
chr20_17842836_17842987 0.35 ENSG00000221220
.
19684
0.18
chr7_36773411_36773562 0.35 AOAH
acyloxyacyl hydrolase (neutrophil)
9332
0.26
chr1_28525614_28525786 0.35 AL353354.2

1370
0.23
chr7_97754790_97754941 0.35 LMTK2
lemur tyrosine kinase 2
18668
0.21
chr16_79127888_79128039 0.35 RP11-556H2.3

4016
0.22
chr11_6761335_6761545 0.35 GVINP1
GTPase, very large interferon inducible pseudogene 1
18329
0.11
chr2_99383332_99383535 0.35 ENSG00000201070
.
15440
0.2
chr17_45277364_45277521 0.35 MYL4
myosin, light chain 4, alkali; atrial, embryonic
8959
0.12
chr6_106233259_106233410 0.35 ENSG00000200198
.
118914
0.06
chr1_108383656_108383813 0.35 ENSG00000265536
.
64856
0.13
chr9_140131740_140131891 0.35 TUBB4B
tubulin, beta 4B class IVb
3850
0.07
chr1_12229589_12229973 0.35 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
2721
0.23
chr22_31610118_31610269 0.35 LIMK2
LIM domain kinase 2
1912
0.2
chr1_22406725_22406944 0.35 CDC42-IT1
CDC42 intronic transcript 1 (non-protein coding)
21144
0.13
chr7_50303021_50303274 0.35 IKZF1
IKAROS family zinc finger 1 (Ikaros)
41177
0.19
chr22_27074499_27074686 0.35 CRYBA4
crystallin, beta A4
56664
0.12
chr2_169964594_169965040 0.35 AC007556.3

7564
0.23
chr9_132757420_132757718 0.35 FNBP1
formin binding protein 1
423
0.86
chr10_28594239_28594390 0.35 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
2319
0.33
chr1_25282389_25282540 0.35 RP11-84D1.1

5372
0.22
chr6_53108184_53108371 0.34 ENSG00000206908
.
24218
0.15
chr16_2771529_2771680 0.34 PRSS27
protease, serine 27
1388
0.23
chr2_101943589_101943800 0.34 ENSG00000264857
.
17782
0.17
chr11_118109252_118109403 0.34 AMICA1
adhesion molecule, interacts with CXADR antigen 1
13518
0.13
chr9_135819078_135819509 0.34 TSC1
tuberous sclerosis 1
715
0.45

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.2 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.1 GO:0002249 lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.2 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.3 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.1 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.4 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.2 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 1.1 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.2 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.3 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.4 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.3 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.5 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0072395 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0000718 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.0 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.5 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.2 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0014826 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824) vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:0014829 regulation of vascular smooth muscle contraction(GO:0003056) vascular smooth muscle contraction(GO:0014829)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.7 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0002861 regulation of inflammatory response to antigenic stimulus(GO:0002861)
0.0 0.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.0 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0009215 purine deoxyribonucleotide metabolic process(GO:0009151) purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.0 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0002864 regulation of acute inflammatory response to antigenic stimulus(GO:0002864)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.0 GO:0001776 leukocyte homeostasis(GO:0001776)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.6 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0044117 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.0 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0042921 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.1 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.3 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.4 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.0 GO:2000514 regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043370) regulation of CD4-positive, alpha-beta T cell activation(GO:2000514)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0002925 regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.4 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.1 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.0 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0002209 behavioral defense response(GO:0002209)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 2.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.0 GO:0003341 cilium movement(GO:0003341)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0060487 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.1 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0010954 positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.0 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0045136 thelarche(GO:0042695) development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:0042345 regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.0 0.0 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.0 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0060969 negative regulation of gene silencing(GO:0060969)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.1 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 0.0 GO:0006026 aminoglycan catabolic process(GO:0006026)
0.0 0.4 GO:0043038 tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.1 GO:0046131 pyrimidine ribonucleoside metabolic process(GO:0046131)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0016265 obsolete death(GO:0016265)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.0 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.3 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0006623 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 0.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.0 GO:0001881 receptor recycling(GO:0001881)
0.0 0.0 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.6 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.0 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) cytochrome complex(GO:0070069)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.4 GO:0005819 spindle(GO:0005819)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)
0.0 1.8 GO:0010008 endosome membrane(GO:0010008)
0.0 0.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.1 GO:0001846 opsonin binding(GO:0001846)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0019864 IgG binding(GO:0019864)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.9 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.5 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0019829 cation-transporting ATPase activity(GO:0019829)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.5 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.0 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis