Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for HES1

Z-value: 1.73

Motif logo

Transcription factors associated with HES1

Gene Symbol	Gene ID	Gene Info
HES1 Ensembl NCBI GeneCards UniProt	ENSG00000114315.3	hes family bHLH transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_193857613_193857764	HES1	3754	0.225086	0.80	9.4e-03	Click!
chr3_193852566_193852717	HES1	1293	0.437742	0.79	1.2e-02	Click!
chr3_193855804_193856156	HES1	2046	0.314617	0.77	1.5e-02	Click!
chr3_193857807_193857958	HES1	3948	0.220687	0.75	1.9e-02	Click!
chr3_193852345_193852559	HES1	1482	0.390311	0.75	2.1e-02	Click!

Activity of the HES1 motif across conditions

Conditions sorted by the z-value of the HES1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_159698543_159698722	0.67	ENSG00000243654	.	20163	0.16
chr15_90756571_90757151	0.62	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	8121	0.12
chr14_105433817_105433968	0.57	AHNAK2	AHNAK nucleoprotein 2	10802	0.16
chr9_139492781_139492932	0.57	ENSG00000252440	.	4111	0.13
chr19_18284786_18284937	0.56	IFI30	interferon, gamma-inducible protein 30	384	0.75
chr2_75426550_75426809	0.55	TACR1	tachykinin receptor 1	147	0.97
chr22_39844539_39844690	0.53	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase	8735	0.15
chr2_149633605_149633756	0.51	KIF5C	kinesin family member 5C	861	0.6
chr17_77775042_77775193	0.50	CBX8	chromobox homolog 8	215	0.81
chr1_55246980_55247131	0.49	TTC22	tetratricopeptide repeat domain 22	6410	0.14
chr21_40362052_40362203	0.49	ENSG00000272015	.	95418	0.08
chr19_10341033_10341420	0.48	ENSG00000264266	.	137	0.8
chr17_80175883_80176034	0.47	RP13-516M14.2		3855	0.12
chr10_43628367_43628518	0.47	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	5492	0.26
chr12_125004479_125004643	0.47	NCOR2	nuclear receptor corepressor 2	1721	0.52
chr11_126256185_126256384	0.46	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	5786	0.19
chr15_68966976_68967185	0.45	CORO2B	coronin, actin binding protein, 2B	42753	0.19
chr19_11670429_11670590	0.44	ZNF627	zinc finger protein 627	246	0.66
chr21_34602504_34602655	0.44	IFNAR2	interferon (alpha, beta and omega) receptor 2	92	0.96
chr5_134871333_134871641	0.43	NEUROG1	neurogenin 1	152	0.95
chr14_76287931_76288578	0.43	RP11-270M14.4		15300	0.24
chr20_19975685_19975836	0.43	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	22000	0.19
chr18_12271616_12271767	0.43	CIDEA	cell death-inducing DFFA-like effector a	17373	0.17
chr7_2680395_2680583	0.43	TTYH3	tweety family member 3	4677	0.21
chr19_33790905_33791151	0.42	CTD-2540B15.11		188	0.87
chr14_70038682_70038904	0.42	CCDC177	coiled-coil domain containing 177	761	0.71
chr17_79022713_79022864	0.42	BAIAP2	BAI1-associated protein 2	4374	0.15
chr9_139492984_139493135	0.41	ENSG00000252440	.	3908	0.13
chr3_9214712_9214921	0.40	SRGAP3-AS2	SRGAP3 antisense RNA 2	19361	0.2
chr17_29822059_29822344	0.40	RAB11FIP4	RAB11 family interacting protein 4 (class II)	7075	0.14
chr17_80626738_80626935	0.39	ENSG00000266107	.	653	0.57
chr15_70877190_70877341	0.39	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	117355	0.06
chr2_8727068_8727219	0.39	AC011747.7		88753	0.09
chr8_6372842_6373023	0.39	ANGPT2	angiopoietin 2	47633	0.16
chr20_58691613_58691835	0.38	C20orf197	chromosome 20 open reading frame 197	60744	0.14
chr9_6412690_6412898	0.38	UHRF2	ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase	529	0.8
chr2_65605736_65605887	0.38	SPRED2	sprouty-related, EVH1 domain containing 2	927	0.57
chr16_88829190_88829356	0.38	RP5-1142A6.8		20044	0.07
chr12_8743487_8743638	0.38	ENSG00000238943	.	1510	0.31
chr6_117197738_117198005	0.38	RFX6	regulatory factor X, 6	552	0.82
chr13_113764915_113765137	0.38	F7	coagulation factor VII (serum prothrombin conversion accelerator)	4905	0.13
chr1_234675740_234675891	0.38	ENSG00000212144	.	53206	0.11
chr10_45476036_45476374	0.37	C10orf10	chromosome 10 open reading frame 10	1947	0.22
chr18_9826704_9827051	0.37	ENSG00000242651	.	3747	0.23
chr6_6694371_6694522	0.37	LY86-AS1	LY86 antisense RNA 1	71442	0.12
chr12_132106364_132106515	0.37	ENSG00000212154	.	39169	0.19
chr22_34249799_34250025	0.36	LARGE	like-glycosyltransferase	7700	0.27
chr2_223170805_223170956	0.36	CCDC140	coiled-coil domain containing 140	3183	0.24
chr13_76060395_76060612	0.36	TBC1D4	TBC1 domain family, member 4	4253	0.26
chr16_136053_136204	0.36	Z69720.2		4501	0.11
chr3_79067067_79067218	0.36	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	552	0.86
chr7_1052092_1052243	0.36	ENSG00000199023	.	10495	0.1
chr14_92912996_92913173	0.36	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	7376	0.28
chr16_29302065_29302340	0.36	RP11-231C14.6		21469	0.17
chr10_111930415_111930653	0.35	MXI1	MAX interactor 1, dimerization protein	36829	0.17
chr17_55478973_55479124	0.35	ENSG00000263902	.	10514	0.26
chr2_113649251_113649402	0.34	IL37	interleukin 37	21222	0.16
chr22_25003244_25003451	0.34	GGT1	gamma-glutamyltransferase 1	241	0.9
chr2_16508691_16508842	0.34	ENSG00000251704	.	128295	0.06
chrX_46421789_46422049	0.34	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	11300	0.2
chr3_127521148_127521315	0.34	MGLL	monoglyceride lipase	18380	0.23
chr1_2467099_2467250	0.34	HES5	hes family bHLH transcription factor 5	5490	0.1
chr18_12630686_12630901	0.34	SPIRE1	spire-type actin nucleation factor 1	22291	0.14
chr19_55952161_55952312	0.34	SHISA7	shisa family member 7	1468	0.21
chr18_9016875_9017135	0.34	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	85623	0.08
chr5_115909413_115909607	0.34	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	581	0.85
chr15_85457860_85458027	0.33	ENSG00000207037	.	23810	0.13
chr9_140201196_140201347	0.33	NRARP	NOTCH-regulated ankyrin repeat protein	4568	0.11
chr13_78492863_78493091	0.33	EDNRB	endothelin receptor type B	11	0.95
chr14_96505703_96505974	0.33	C14orf132	chromosome 14 open reading frame 132	177	0.97
chr4_4854778_4854948	0.33	MSX1	msh homeobox 1	6530	0.29
chr2_206611565_206611716	0.33	AC007362.3		17037	0.25
chr2_85169512_85169765	0.33	KCMF1	potassium channel modulatory factor 1	28578	0.16
chr15_40627004_40627253	0.33	C15orf52	chromosome 15 open reading frame 52	3113	0.1
chr2_45169664_45169815	0.33	SIX3-AS1	SIX3 antisense RNA 1	727	0.48
chr7_105711867_105712305	0.33	SYPL1	synaptophysin-like 1	26222	0.22
chr22_39171379_39171530	0.33	SUN2	Sad1 and UNC84 domain containing 2	18694	0.08
chr7_1553312_1553509	0.32	AC102953.6		4347	0.16
chr21_43499892_43500191	0.32	UMODL1	uromodulin-like 1	8615	0.2
chr4_9500064_9500220	0.32	ENSG00000266246	.	27445	0.14
chr5_76926843_76927107	0.32	OTP	orthopedia homeobox	8538	0.23
chr2_28491600_28491751	0.32	AC093690.1		41651	0.17
chr10_130008845_130008996	0.32	MKI67	marker of proliferation Ki-67	84271	0.11
chr9_139518117_139518268	0.32	ENSG00000252440	.	21225	0.09
chr4_146655160_146655429	0.32	ZNF827	zinc finger protein 827	30913	0.18
chr16_81681030_81681181	0.32	CMIP	c-Maf inducing protein	2142	0.44
chr2_148601579_148601730	0.32	ACVR2A	activin A receptor, type IIA	432	0.86
chr2_127821817_127821968	0.31	BIN1	bridging integrator 1	42685	0.16
chr11_60793650_60793801	0.31	CD6	CD6 molecule	17719	0.14
chr17_39949185_39949336	0.31	JUP	junction plakoglobin	6077	0.1
chr19_6237168_6237353	0.31	CTC-503J8.4		21908	0.13
chr18_76828740_76828968	0.31	ATP9B	ATPase, class II, type 9B	431	0.88
chr22_42696158_42696356	0.31	TCF20	transcription factor 20 (AR1)	43365	0.14
chr2_197790785_197790936	0.31	PGAP1	post-GPI attachment to proteins 1	594	0.82
chr1_205474854_205475005	0.31	CDK18	cyclin-dependent kinase 18	999	0.52
chr12_66289957_66290108	0.31	RP11-366L20.2	Uncharacterized protein	14085	0.17
chr8_8820802_8821008	0.31	ENSG00000207244	.	1820	0.35
chr5_139702623_139702774	0.30	PFDN1	prefoldin subunit 1	19992	0.11
chr21_40382908_40383154	0.30	ENSG00000272015	.	116322	0.06
chr22_40417826_40418098	0.30	FAM83F	family with sequence similarity 83, member F	12270	0.17
chr7_140098371_140098524	0.30	SLC37A3	solute carrier family 37, member 3	98	0.95
chr16_728352_728503	0.30	LA16c-313D11.9		1310	0.14
chr6_170501787_170501938	0.30	RP11-302L19.1		24121	0.21
chr6_106442714_106442865	0.30	ENSG00000200198	.	90541	0.08
chr14_24744790_24744941	0.30	RABGGTA	Rab geranylgeranyltransferase, alpha subunit	3920	0.08
chr10_126754116_126754381	0.30	ENSG00000264572	.	32809	0.18
chr16_1583661_1583861	0.30	TMEM204	transmembrane protein 204	187	0.58
chr8_28269829_28269980	0.30	ENSG00000207361	.	4061	0.15
chr10_134331119_134331391	0.30	LINC01165	long intergenic non-protein coding RNA 1165	4698	0.23
chr19_11454879_11455424	0.30	CCDC159	coiled-coil domain containing 159	826	0.33
chr16_70728443_70728594	0.30	VAC14	Vac14 homolog (S. cerevisiae)	978	0.47
chr3_188374207_188374358	0.29	ENSG00000264114	.	25792	0.18
chr11_3022061_3022212	0.29	NAP1L4	nucleosome assembly protein 1-like 4	8529	0.12
chr17_4539926_4540256	0.29	ALOX15	arachidonate 15-lipoxygenase	3086	0.15
chr18_57024288_57024928	0.29	LMAN1	lectin, mannose-binding, 1	2586	0.31
chr2_73496289_73496440	0.29	FBXO41	F-box protein 41	1679	0.29
chr8_22548474_22548625	0.29	ENSG00000253125	.	886	0.41
chr11_57243945_57244096	0.29	RP11-624G17.3		987	0.35
chr12_125066547_125066772	0.29	NCOR2	nuclear receptor corepressor 2	14649	0.29
chr1_45279609_45279760	0.29	BTBD19	BTB (POZ) domain containing 19	5489	0.08
chr12_125093364_125093593	0.29	NCOR2	nuclear receptor corepressor 2	41468	0.21
chr19_49623573_49623831	0.29	PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	1056	0.24
chr1_43405930_43406090	0.29	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	9214	0.19
chr3_47422515_47422816	0.29	PTPN23	protein tyrosine phosphatase, non-receptor type 23	155	0.52
chr6_15017519_15017967	0.28	ENSG00000242989	.	95456	0.09
chr1_15417388_15417539	0.28	TMEM51	transmembrane protein 51	61565	0.12
chr11_57282126_57282281	0.28	SLC43A1	solute carrier family 43 (amino acid system L transporter), member 1	115	0.93
chr10_75576591_75576838	0.28	RP11-574K11.5		3438	0.11
chr1_154973632_154973783	0.28	ZBTB7B	zinc finger and BTB domain containing 7B	1420	0.19
chr17_45949568_45949785	0.28	SP6	Sp6 transcription factor	16436	0.1
chr18_13136764_13137008	0.28	RP11-794M8.1		79438	0.08
chr17_26708216_26708463	0.28	SARM1	sterile alpha and TIR motif containing 1	3780	0.08
chr17_79700663_79700814	0.28	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	20266	0.08
chr1_1851146_1851342	0.28	TMEM52	transmembrane protein 52	532	0.68
chr11_126870671_126870822	0.28	KIRREL3	kin of IRRE like 3 (Drosophila)	40	0.97
chr14_52781492_52781643	0.28	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	454	0.87
chr4_155412274_155412591	0.28	DCHS2	dachsous cadherin-related 2	54	0.98
chr14_105190142_105190317	0.28	ADSSL1	adenylosuccinate synthase like 1	294	0.85
chr7_2719075_2719226	0.28	AMZ1	archaelysin family metallopeptidase 1	6	0.98
chr14_35806722_35806916	0.28	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	26780	0.19
chr12_6472314_6472494	0.28	SCNN1A	sodium channel, non-voltage-gated 1 alpha subunit	909	0.44
chr18_9658030_9658181	0.28	ENSG00000212572	.	40035	0.13
chr4_153944645_153944833	0.28	FHDC1	FH2 domain containing 1	80604	0.1
chr4_106473330_106473481	0.27	AC004066.3		107	0.8
chr11_75141053_75141204	0.27	KLHL35	kelch-like family member 35	108	0.95
chr16_15489705_15489922	0.27	MPV17L	MPV17 mitochondrial membrane protein-like	177	0.53
chr1_3073557_3073708	0.27	RP1-163G9.2		23359	0.22
chr11_316451_316602	0.27	RP11-326C3.11		2114	0.12
chr12_32739624_32739775	0.27	FGD4	FYVE, RhoGEF and PH domain containing 4	11761	0.26
chr16_8963146_8963297	0.27	RP11-77H9.6		113	0.77
chr20_1783720_1783871	0.27	SIRPA	signal-regulatory protein alpha	91359	0.07
chr19_56729074_56729225	0.27	ZSCAN5A	zinc finger and SCAN domain containing 5A	10510	0.1
chr21_37539073_37539317	0.27	DOPEY2	dopey family member 2	2362	0.21
chr1_27424839_27425237	0.27	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	55935	0.1
chr16_57418029_57418329	0.27	CX3CL1	chemokine (C-X3-C motif) ligand 1	7295	0.14
chr20_35490317_35490468	0.27	SOGA1	suppressor of glucose, autophagy associated 1	1697	0.32
chr17_7976584_7976755	0.27	AC129492.6		6131	0.1
chr7_20447658_20447906	0.27	ENSG00000200753	.	30828	0.2
chr11_316119_316270	0.27	IFITM1	interferon induced transmembrane protein 1	2341	0.11
chr12_124875119_124875344	0.27	NCOR2	nuclear receptor corepressor 2	1861	0.47
chr7_150785539_150785789	0.27	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	1510	0.21
chr20_24487977_24488128	0.27	SYNDIG1	synapse differentiation inducing 1	38217	0.23
chr11_2933384_2933685	0.27	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense	8564	0.12
chr16_81819777_81819928	0.27	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	6989	0.3
chr7_6463832_6463983	0.27	DAGLB	diacylglycerol lipase, beta	23656	0.14
chr22_50743271_50743434	0.27	PLXNB2	plexin B2	2665	0.13
chr12_49175027_49175178	0.26	ADCY6	adenylate cyclase 6	2775	0.14
chr15_92972455_92972606	0.26	ENSG00000239197	.	11753	0.21
chr9_101009625_101009776	0.26	TBC1D2	TBC1 domain family, member 2	8162	0.26
chr2_121493910_121494153	0.26	GLI2	GLI family zinc finger 2	208	0.97
chr21_44877468_44877619	0.26	SIK1	salt-inducible kinase 1	30535	0.22
chr22_41633966_41634117	0.26	CHADL	chondroadherin-like	1584	0.26
chr19_16832133_16832284	0.26	NWD1	NACHT and WD repeat domain containing 1	1348	0.35
chr3_5053541_5053692	0.26	BHLHE40-AS1	BHLHE40 antisense RNA 1	31970	0.16
chr4_74702269_74702510	0.26	CXCL6	chemokine (C-X-C motif) ligand 6	32	0.97
chr19_49199324_49199475	0.26	FUT2	fucosyltransferase 2 (secretor status included)	167	0.89
chr9_116311007_116311158	0.26	RGS3	regulator of G-protein signaling 3	12298	0.22
chr2_110089754_110089905	0.26	ENSG00000265965	.	159748	0.04
chr10_33624786_33624937	0.26	NRP1	neuropilin 1	329	0.93
chr19_3434984_3435135	0.26	C19orf77	chromosome 19 open reading frame 77	43427	0.09
chr7_130126161_130126414	0.26	MEST	mesoderm specific transcript	92	0.72
chr8_33422808_33423410	0.26	RNF122	ring finger protein 122	1534	0.32
chr10_43601194_43601376	0.26	RET	ret proto-oncogene	28758	0.18
chr17_56013451_56013655	0.26	CUEDC1	CUE domain containing 1	19065	0.15
chr2_91777481_91777632	0.26	AC027612.6		65973	0.12
chr8_142127178_142127329	0.26	DENND3	DENN/MADD domain containing 3	124	0.97
chr7_25020987_25021202	0.26	OSBPL3	oxysterol binding protein-like 3	159	0.97
chr1_110198897_110199147	0.26	GSTM4	glutathione S-transferase mu 4	64	0.94
chr21_39644201_39644352	0.26	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	59	0.99
chr10_80993935_80994181	0.26	ZMIZ1	zinc finger, MIZ-type containing 1	71917	0.11
chr19_36135685_36136013	0.26	ETV2	ets variant 2	1281	0.23
chr14_74036409_74036560	0.26	ACOT2	acyl-CoA thioesterase 2	721	0.52
chr17_79824826_79825163	0.26	RP11-498C9.3		603	0.43
chr18_46308841_46308992	0.26	RP11-484L8.1		52225	0.15
chr20_43245004_43245155	0.26	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	2130	0.23
chr7_157225515_157225699	0.26	AC006372.6		80381	0.09
chr19_1508442_1508669	0.25	CTB-25B13.9		174	0.82
chr16_68292014_68292165	0.25	RP11-96D1.7		681	0.44
chr20_60945361_60945512	0.25	LAMA5	laminin, alpha 5	3068	0.16
chr8_23410060_23410288	0.25	AC051642.1		10477	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.2	0.6	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.2	0.3	GO:0042713	sperm ejaculation(GO:0042713)
0.1	0.4	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.4	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.2	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.3	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.3	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.3	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.3	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.1	0.2	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.2	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.2	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1	0.2	GO:0060206	estrous cycle phase(GO:0060206)
0.1	0.2	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.1	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.3	GO:0043276	anoikis(GO:0043276)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.2	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0046033	AMP metabolic process(GO:0046033)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.5	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	0.2	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.2	GO:0019605	butyrate metabolic process(GO:0019605)
0.1	0.2	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1	0.2	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0071504	cellular response to heparin(GO:0071504)
0.0	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0046021	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.2	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.2	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.3	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.4	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.3	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.2	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0009997	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.0	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.3	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0072110	glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.0	0.3	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.2	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0051608	histamine transport(GO:0051608)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0031650	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0	0.2	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0060405	regulation of penile erection(GO:0060405)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.1	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.2	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.4	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.2	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.6	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.2	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.3	GO:0051145	smooth muscle cell differentiation(GO:0051145)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.5	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.2	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0060558	regulation of vitamin metabolic process(GO:0030656) vitamin D biosynthetic process(GO:0042368) regulation of vitamin D biosynthetic process(GO:0060556) regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.0	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0060433	bronchus development(GO:0060433)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0071071	regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.2	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.0	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.1	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.0	GO:1904748	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.0	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.2	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.1	GO:0085029	extracellular matrix assembly(GO:0085029)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0033483	oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0002830	positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) iris morphogenesis(GO:0061072)
0.0	0.1	GO:0048247	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.2	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.0	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0010922	positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.2	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.0	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0051057	positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0070307	lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.2	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.3	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	0.4	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.0	GO:0016589	NURF complex(GO:0016589)
0.0	0.6	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.3	GO:0034711	inhibin binding(GO:0034711)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.5	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.7	GO:0005112	Notch binding(GO:0005112)
0.1	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.3	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.2	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.3	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0005497	androgen binding(GO:0005497)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.4	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.3	GO:0032934	sterol binding(GO:0032934)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.0	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.0	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.6	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.3	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.1	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES	Genes involved in Transmembrane transport of small molecules
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer

Results for HES1

Z-value: 1.73

Motif logo

Transcription factors associated with HES1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HES1 motif across conditions

Conditions sorted by the z-value of the HES1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: