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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HES7_HES5

Z-value: 0.55

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Transcription factors associated with HES7_HES5

Gene Symbol	Gene ID	Gene Info
HES7 Ensembl NCBI GeneCards UniProt	ENSG00000179111.4	hes family bHLH transcription factor 7
HES5 Ensembl NCBI GeneCards UniProt	ENSG00000197921.5	hes family bHLH transcription factor 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_2473159_2473310	HES5	11550	0.089609	-0.35	3.5e-01	Click!
chr1_2472569_2472730	HES5	10965	0.090434	0.21	5.9e-01	Click!
chr1_2466100_2466356	HES5	4544	0.109246	-0.21	5.9e-01	Click!
chr1_2471790_2472028	HES5	10225	0.091524	-0.16	6.8e-01	Click!
chr1_2472403_2472554	HES5	10794	0.090680	0.14	7.1e-01	Click!
chr17_8030164_8030365	HES7	2854	0.116782	0.37	3.3e-01	Click!
chr17_8025338_8025489	HES7	1989	0.150994	0.35	3.6e-01	Click!
chr17_8026134_8026345	HES7	1163	0.265348	0.29	4.6e-01	Click!
chr17_8026960_8027182	HES7	331	0.748773	0.25	5.2e-01	Click!
chr17_8025866_8026098	HES7	1420	0.212818	0.22	5.8e-01	Click!

Activity of the HES7_HES5 motif across conditions

Conditions sorted by the z-value of the HES7_HES5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_55604345_55604638	0.26	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	896	0.67
chr22_20785559_20785830	0.25	SCARF2	scavenger receptor class F, member 2	6418	0.12
chr10_11892041_11892192	0.23	PROSER2	proline and serine-rich protein 2	18434	0.19
chr5_77161267_77161418	0.23	TBCA	tubulin folding cofactor A	3262	0.38
chr19_1418111_1418262	0.22	CTB-25B13.13		4286	0.08
chr11_17519733_17519884	0.20	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	21359	0.17
chr1_162342160_162342311	0.19	C1orf111	chromosome 1 open reading frame 111	4425	0.13
chr17_71994614_71994765	0.19	RPL38	ribosomal protein L38	205032	0.02
chr14_35586352_35586588	0.19	KIAA0391	KIAA0391	4582	0.22
chr11_35640709_35641024	0.18	FJX1	four jointed box 1 (Drosophila)	1131	0.58
chr17_19213514_19213665	0.18	EPN2-AS1	EPN2 antisense RNA 1	4015	0.14
chr6_85484508_85484659	0.18	TBX18	T-box 18	10346	0.3
chr11_126336020_126336230	0.18	KIRREL3	kin of IRRE like 3 (Drosophila)	25672	0.18
chr1_220962364_220962515	0.18	MARC1	mitochondrial amidoxime reducing component 1	2338	0.3
chr16_85675576_85675727	0.18	GSE1	Gse1 coiled-coil protein	12387	0.16
chr12_94242890_94243084	0.17	RP11-887P2.6		13044	0.2
chr6_143771407_143771558	0.17	ADAT2	adenosine deaminase, tRNA-specific 2	328	0.47
chr19_14544657_14544808	0.16	PKN1	protein kinase N1	427	0.74
chr10_134496809_134496960	0.16	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	75454	0.1
chr3_81783533_81783684	0.16	GBE1	glucan (1,4-alpha-), branching enzyme 1	9172	0.33
chr7_74569134_74569285	0.16	GTF2IRD2B	GTF2I repeat domain containing 2B	12305	0.24
chr6_3745494_3745645	0.16	RP11-420L9.5		5776	0.22
chr9_92113326_92114071	0.15	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	653	0.53
chr7_99719791_99720047	0.15	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	2455	0.09
chrX_40132852_40133003	0.15	ENSG00000238920	.	11422	0.29
chr2_85734499_85734650	0.15	ENSG00000266577	.	25175	0.08
chr1_200983563_200983714	0.15	KIF21B	kinesin family member 21B	8898	0.19
chr1_46154147_46154314	0.15	TMEM69	transmembrane protein 69	1344	0.32
chr11_48029484_48029819	0.15	AC103828.1		7756	0.21
chr2_240197215_240197647	0.15	ENSG00000265215	.	29726	0.15
chr9_140349393_140349643	0.14	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor	357	0.79
chr19_935004_935155	0.14	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	2570	0.12
chr10_6190085_6190387	0.14	ENSG00000201581	.	1350	0.31
chr5_156627118_156627269	0.13	ITK	IL2-inducible T-cell kinase	19356	0.12
chr3_196015117_196015307	0.13	PCYT1A	phosphate cytidylyltransferase 1, choline, alpha	384	0.78
chr1_23944860_23945102	0.13	MDS2	myelodysplastic syndrome 2 translocation associated	8843	0.19
chr17_58228988_58229139	0.13	CA4	carbonic anhydrase IV	1760	0.34
chrX_153248886_153249110	0.13	ENSG00000265176	.	2450	0.14
chr22_20120033_20120203	0.13	ZDHHC8	zinc finger, DHHC-type containing 8	647	0.5
chr16_53489129_53489352	0.13	RBL2	retinoblastoma-like 2 (p130)	5252	0.17
chr5_171556780_171557174	0.13	ENSG00000266671	.	48997	0.13
chr11_63685536_63685687	0.12	RCOR2	REST corepressor 2	1295	0.32
chr1_2326788_2326939	0.12	RER1	retention in endoplasmic reticulum sorting receptor 1	1419	0.24
chr10_64843902_64844053	0.12	ENSG00000199446	.	25922	0.19
chr4_114679628_114679779	0.12	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	2521	0.44
chr12_47601769_47602062	0.12	PCED1B	PC-esterase domain containing 1B	8137	0.22
chr19_1238693_1238844	0.12	C19orf26	chromosome 19 open reading frame 26	742	0.43
chr1_223402859_223403010	0.11	TLR5	toll-like receptor 5	86310	0.09
chrX_80065881_80066270	0.11	BRWD3	bromodomain and WD repeat domain containing 3	888	0.69
chr3_25825314_25825465	0.11	NGLY1	N-glycanase 1	347	0.75
chr1_9180295_9180446	0.11	GPR157	G protein-coupled receptor 157	8813	0.17
chr5_14385266_14385417	0.11	TRIO	trio Rho guanine nucleotide exchange factor	94255	0.09
chr11_33037755_33037906	0.11	DEPDC7	DEP domain containing 7	120	0.96
chr10_105789345_105789496	0.11	COL17A1	collagen, type XVII, alpha 1	3306	0.22
chr12_102165691_102165954	0.11	ENSG00000222255	.	6535	0.11
chr19_41922415_41922566	0.11	BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide	5863	0.09
chr4_154380641_154380792	0.11	KIAA0922	KIAA0922	6782	0.26
chr2_217542751_217542902	0.11	AC007563.5		16361	0.15
chr16_29167036_29167187	0.11	CTB-134H23.3		48345	0.11
chr20_55965760_55966107	0.10	RBM38	RNA binding motif protein 38	530	0.69
chr16_89469756_89470099	0.10	RP1-168P16.2		9045	0.14
chr5_139973795_139973946	0.10	ENSG00000200235	.	14618	0.08
chr13_22637652_22638073	0.10	ENSG00000244197	.	273186	0.02
chr1_27950347_27950704	0.10	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	48	0.97
chr5_1513019_1513170	0.10	LPCAT1	lysophosphatidylcholine acyltransferase 1	10998	0.22
chr4_140476576_140476762	0.10	SETD7	SET domain containing (lysine methyltransferase) 7	693	0.59
chr6_137144118_137144500	0.10	PEX7	peroxisomal biogenesis factor 7	586	0.76
chr2_234150995_234151190	0.10	ATG16L1	autophagy related 16-like 1 (S. cerevisiae)	9125	0.15
chr19_42396817_42397275	0.10	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	1319	0.31
chr4_103737282_103737795	0.10	UBE2D3	ubiquitin-conjugating enzyme E2D 3	9161	0.15
chr2_232917540_232917691	0.10	AC105461.1		37185	0.16
chr18_45755490_45755641	0.10	AC091150.1	HCG1818186; Uncharacterized protein	23107	0.19
chr14_104604037_104604479	0.10	CTD-2223O18.1		23	0.94
chr10_42738180_42738331	0.10	ENSG00000264398	.	7832	0.28
chr6_111203655_111204086	0.10	AMD1	adenosylmethionine decarboxylase 1	7092	0.17
chr19_54812861_54813012	0.09	LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	2984	0.12
chrX_70401426_70401720	0.09	RP5-1091N2.9		16452	0.12
chr16_81129207_81129532	0.09	GCSH	glycine cleavage system protein H (aminomethyl carrier)	476	0.71
chr1_204253068_204253219	0.09	RP11-203F10.5		7010	0.2
chrX_39928105_39928256	0.09	BCOR	BCL6 corepressor	807	0.78
chr7_65366081_65366232	0.09	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	27800	0.16
chr10_8306294_8306445	0.09	GATA3	GATA binding protein 3	209600	0.03
chr14_105166825_105166976	0.09	INF2	inverted formin, FH2 and WH2 domain containing	7301	0.13
chr22_35730206_35730357	0.09	ENSG00000266320	.	1352	0.4
chr6_11332687_11332838	0.09	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	49770	0.16
chr13_76209699_76209926	0.09	RP11-173B14.5		318	0.71
chrX_12937770_12937921	0.09	TLR8-AS1	TLR8 antisense RNA 1	11393	0.19
chr15_22483712_22483863	0.09	IGHV1OR15-4	immunoglobulin heavy variable 1/OR15-4 (pseudogene)	519	0.69
chr17_80171257_80171663	0.09	RP13-516M14.2		643	0.41
chrX_39179559_39179819	0.09	ENSG00000207122	.	239151	0.02
chr3_86416939_86417090	0.09	ENSG00000222934	.	5732	0.34
chr7_149485831_149485982	0.09	ZNF467	zinc finger protein 467	15338	0.19
chr2_113925026_113925412	0.09	PSD4	pleckstrin and Sec7 domain containing 4	6329	0.15
chr19_39892381_39892634	0.08	ZFP36	ZFP36 ring finger protein	4946	0.08
chr19_40225624_40225775	0.08	CLC	Charcot-Leyden crystal galectin	2969	0.19
chr3_72158863_72159014	0.08	ENSG00000212070	.	152641	0.04
chr13_46365670_46365821	0.08	SIAH3	siah E3 ubiquitin protein ligase family member 3	60126	0.12
chr11_44681020_44681182	0.08	CD82	CD82 molecule	41281	0.15
chr8_41734096_41734247	0.08	ANK1	ankyrin 1, erythrocytic	20109	0.18
chr11_9665537_9665688	0.08	SWAP70	SWAP switching B-cell complex 70kDa subunit	20012	0.16
chr13_114862694_114862923	0.08	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	11487	0.22
chr22_38214433_38214603	0.08	GALR3	galanin receptor 3	4871	0.1
chr14_66308035_66308186	0.08	CTD-2014B16.3	Uncharacterized protein	163131	0.04
chr4_2819205_2819714	0.08	SH3BP2	SH3-domain binding protein 2	453	0.83
chr20_57268529_57268804	0.08	NPEPL1	aminopeptidase-like 1	997	0.5
chrX_130027668_130027939	0.08	ENOX2	ecto-NOX disulfide-thiol exchanger 2	9375	0.3
chr15_55619953_55620104	0.08	PIGB	phosphatidylinositol glycan anchor biosynthesis, class B	8585	0.15
chrX_9486353_9486504	0.08	TBL1X	transducin (beta)-like 1X-linked	16555	0.3
chr2_75066333_75066484	0.08	HK2	hexokinase 2	4111	0.3
chr22_50523315_50523466	0.08	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1	298	0.86
chr10_82224653_82225144	0.08	TSPAN14	tetraspanin 14	5840	0.23
chr22_42310292_42310562	0.08	SHISA8	shisa family member 8	143	0.92
chr5_53831366_53831517	0.08	SNX18	sorting nexin 18	17848	0.26
chr5_53838074_53838225	0.08	SNX18	sorting nexin 18	24556	0.25
chr5_6718428_6718667	0.08	PAPD7	PAP associated domain containing 7	3802	0.32
chr19_40440819_40441084	0.08	FCGBP	Fc fragment of IgG binding protein	418	0.82
chr3_130542365_130542516	0.08	ENSG00000222783	.	11501	0.2
chr1_17019441_17019592	0.08	ENSG00000264742	.	11766	0.12
chr15_51476418_51476569	0.07	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	30928	0.17
chr9_139836823_139836974	0.07	FBXW5	F-box and WD repeat domain containing 5	280	0.75
chr9_135092130_135092281	0.07	ENSG00000221105	.	1943	0.41
chr14_106967843_106968018	0.07	IGHV1-46	immunoglobulin heavy variable 1-46	142	0.82
chr18_74280231_74280382	0.07	LINC00908	long intergenic non-protein coding RNA 908	39432	0.16
chr15_31659811_31660031	0.07	KLF13	Kruppel-like factor 13	1564	0.55
chr22_46997813_46997964	0.07	GRAMD4	GRAM domain containing 4	18411	0.21
chr11_12398290_12398441	0.07	PARVA	parvin, alpha	367	0.89
chr7_138435270_138435447	0.07	ATP6V0A4	ATPase, H+ transporting, lysosomal V0 subunit a4	23424	0.18
chr17_42462131_42462433	0.07	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	406	0.76
chr11_64064837_64065015	0.07	ENSG00000207024	.	1417	0.16
chrX_39963823_39964258	0.07	BCOR	BCL6 corepressor	7384	0.32
chr7_157205057_157205285	0.07	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	72656	0.1
chr10_119303115_119303318	0.07	EMX2	empty spiracles homeobox 2	707	0.63
chr2_240211896_240212145	0.07	ENSG00000265215	.	15137	0.18
chr6_159192572_159192723	0.07	ENSG00000265558	.	6862	0.21
chr4_113351506_113351657	0.07	RP11-402J6.1		84960	0.07
chr10_73503024_73503387	0.07	C10orf105	chromosome 10 open reading frame 105	5624	0.22
chr21_34395992_34396143	0.07	OLIG2	oligodendrocyte lineage transcription factor 2	2086	0.33
chr11_2291133_2291433	0.07	ASCL2	achaete-scute family bHLH transcription factor 2	899	0.5
chr8_141644530_141644748	0.07	AGO2	argonaute RISC catalytic component 2	1006	0.61
chr12_124985454_124985605	0.07	NCOR2	nuclear receptor corepressor 2	5731	0.33
chr6_167161616_167161767	0.07	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	9708	0.28
chr16_4428001_4428209	0.07	VASN	vasorin	6256	0.13
chr17_76310134_76310416	0.07	SOCS3	suppressor of cytokine signaling 3	45880	0.1
chr13_114814477_114814986	0.07	RASA3	RAS p21 protein activator 3	28707	0.21
chr16_85089467_85090023	0.07	KIAA0513	KIAA0513	7073	0.23
chr4_94749842_94750092	0.07	ATOH1	atonal homolog 1 (Drosophila)	75	0.98
chr4_10551040_10551191	0.07	CLNK	cytokine-dependent hematopoietic cell linker	32026	0.23
chr21_45564013_45564179	0.07	C21orf33	chromosome 21 open reading frame 33	8095	0.15
chr6_151865308_151865459	0.07	CCDC170	coiled-coil domain containing 170	50208	0.13
chr22_23527174_23527568	0.07	BCR	breakpoint cluster region	4819	0.16
chrX_70763186_70763395	0.07	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase	6426	0.2
chr1_227133221_227133372	0.07	ADCK3	aarF domain containing kinase 3	5301	0.25
chr4_2822258_2822409	0.06	SH3BP2	SH3-domain binding protein 2	1792	0.36
chr12_1579383_1579534	0.06	WNT5B	wingless-type MMTV integration site family, member 5B	59599	0.11
chr9_139303294_139303653	0.06	SDCCAG3	serologically defined colon cancer antigen 3	1247	0.26
chr10_71905217_71905368	0.06	TYSND1	trypsin domain containing 1	1050	0.5
chr17_5014893_5015044	0.06	ZNF232	zinc finger protein 232	168	0.53
chr12_4928730_4928976	0.06	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	10511	0.2
chr17_72304461_72304612	0.06	ENSG00000252785	.	589	0.55
chr14_97927674_97927825	0.06	ENSG00000240730	.	68761	0.14
chr14_105527301_105527518	0.06	GPR132	G protein-coupled receptor 132	3590	0.23
chr5_131817472_131817699	0.06	IRF1	interferon regulatory factor 1	7752	0.13
chr11_64108441_64109145	0.06	CCDC88B	coiled-coil domain containing 88B	1098	0.27
chr2_10540752_10540903	0.06	HPCAL1	hippocalcin-like 1	19320	0.18
chr19_5138285_5138436	0.06	CTC-482H14.5		39770	0.16
chr21_45721457_45721805	0.06	PFKL	phosphofructokinase, liver	1697	0.21
chr11_7561884_7562035	0.06	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	1550	0.38
chr20_31096106_31096363	0.06	C20orf112	chromosome 20 open reading frame 112	2976	0.25
chr17_42988559_42988831	0.06	GFAP	glial fibrillary acidic protein	676	0.51
chr11_1767689_1767840	0.06	IFITM10	interferon induced transmembrane protein 10	4057	0.11
chr9_96715477_96715717	0.06	BARX1	BARX homeobox 1	116	0.98
chr7_149567890_149568136	0.06	ATP6V0E2	ATPase, H+ transporting V0 subunit e2	2044	0.26
chr5_178054496_178054708	0.06	CLK4	CDC-like kinase 4	487	0.8
chr8_142397145_142397301	0.06	PTP4A3	protein tyrosine phosphatase type IVA, member 3	4870	0.13
chr6_139695930_139696081	0.06	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	248	0.95
chr10_102500685_102500836	0.06	PAX2	paired box 2	4708	0.28
chr3_53157618_53157769	0.06	RFT1	RFT1 homolog (S. cerevisiae)	6734	0.19
chr14_99502237_99502388	0.06	AL162151.4		122441	0.06
chr20_56232956_56233107	0.06	PMEPA1	prostate transmembrane protein, androgen induced 1	32649	0.17
chr4_106227685_106227836	0.06	ENSG00000243383	.	12945	0.26
chr1_92196423_92196574	0.06	ENSG00000239794	.	99133	0.08
chr11_65380533_65380748	0.06	MAP3K11	mitogen-activated protein kinase kinase kinase 11	1073	0.26
chr1_205247824_205248121	0.06	TMCC2	transmembrane and coiled-coil domain family 2	22643	0.15
chr9_139790608_139790759	0.06	TRAF2	TNF receptor-associated factor 2	6696	0.08
chr15_31325370_31325521	0.06	RP11-348B17.1		7036	0.18
chr3_12438460_12438611	0.06	PPARG	peroxisome proliferator-activated receptor gamma	45564	0.15
chr1_227917436_227917587	0.06	SNAP47	synaptosomal-associated protein, 47kDa	1153	0.45
chr7_74206755_74206906	0.06	GTF2IRD2	GTF2I repeat domain containing 2	14458	0.18
chr12_46760698_46760932	0.06	SLC38A2	solute carrier family 38, member 2	1725	0.42
chr3_196367115_196367900	0.06	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	861	0.37
chr20_55012223_55012374	0.06	ENSG00000212084	.	23115	0.11
chr8_96192088_96192282	0.06	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	45881	0.15
chr15_40453377_40453695	0.06	BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	268	0.9
chr10_7299238_7299582	0.06	SFMBT2	Scm-like with four mbt domains 2	151297	0.04
chrX_152518761_152518912	0.06	MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	32721	0.15
chr3_71413120_71413271	0.06	FOXP1	forkhead box P1	59284	0.14
chr17_39932161_39932357	0.06	JUP	junction plakoglobin	3738	0.13
chr9_31335901_31336264	0.06	ENSG00000211510	.	561856	0.0
chr2_37552318_37552512	0.06	PRKD3	protein kinase D3	464	0.79
chr1_38142298_38142449	0.06	C1orf109	chromosome 1 open reading frame 109	13803	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	GO:0050693	LBD domain binding(GO:0050693)
0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Results for HES7_HES5

Z-value: 0.55

Motif logo

Transcription factors associated with HES7_HES5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HES7_HES5 motif across conditions

Conditions sorted by the z-value of the HES7_HES5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category: