Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HESX1

Z-value: 1.29

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Transcription factors associated with HESX1

Gene Symbol Gene ID Gene Info
ENSG00000163666.4 HESX homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr3_57258884_57259035HESX115900.3443560.863.2e-03Click!
chr3_57230333_57230484HESX135580.2255110.627.2e-02Click!
chr3_57233953_57234104HESX1450.9753880.561.2e-01Click!
chr3_57258671_57258822HESX118030.3141270.472.0e-01Click!
chr3_57260204_57260355HESX12700.8776030.353.6e-01Click!

Activity of the HESX1 motif across conditions

Conditions sorted by the z-value of the HESX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_2933384_2933685 0.65 SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
8564
0.12
chr2_232229722_232230070 0.44 ENSG00000263641
.
2477
0.26
chr18_9016875_9017135 0.41 NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
85623
0.08
chr2_87901691_87901863 0.39 ENSG00000265507
.
27497
0.24
chr5_145356260_145356548 0.39 SH3RF2
SH3 domain containing ring finger 2
38964
0.18
chr16_70780334_70780534 0.38 RP11-394B2.6

526
0.69
chr7_20447658_20447906 0.37 ENSG00000200753
.
30828
0.2
chrX_69697630_69697850 0.35 DLG3-AS1
DLG3 antisense RNA 1
21896
0.14
chr8_122360906_122361134 0.33 ENSG00000221644
.
161888
0.04
chr18_21464195_21464346 0.32 LAMA3
laminin, alpha 3
467
0.84
chr7_100322881_100323094 0.32 EPO
erythropoietin
4564
0.12
chr1_46649466_46650029 0.31 PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
7587
0.12
chr1_22231017_22231447 0.31 HSPG2
heparan sulfate proteoglycan 2
8429
0.18
chr8_30333332_30333499 0.31 RBPMS
RNA binding protein with multiple splicing
33282
0.2
chr2_9374494_9374810 0.30 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
27758
0.24
chr2_19850164_19850315 0.30 TTC32
tetratricopeptide repeat domain 32
251163
0.02
chr1_183776609_183776992 0.29 RGL1
ral guanine nucleotide dissociation stimulator-like 1
2510
0.36
chr3_149291004_149291431 0.29 WWTR1
WW domain containing transcription regulator 1
2822
0.29
chr11_13157469_13157634 0.28 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
140648
0.04
chr3_71591322_71591805 0.28 ENSG00000221264
.
323
0.83
chr18_53156534_53156869 0.28 RP11-619L19.2

2705
0.26
chr10_14823935_14824305 0.28 FAM107B
family with sequence similarity 107, member B
7224
0.22
chr4_124477064_124477262 0.28 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
156040
0.04
chr7_75920639_75920802 0.28 ENSG00000263569
.
2612
0.23
chr6_153450838_153450989 0.27 RGS17
regulator of G-protein signaling 17
1471
0.45
chr8_49332411_49332756 0.27 ENSG00000252710
.
111993
0.07
chr9_84646672_84646823 0.27 SPATA31D1
SPATA31 subfamily D, member 1
43060
0.17
chr16_58058882_58059051 0.27 MMP15
matrix metallopeptidase 15 (membrane-inserted)
504
0.72
chr12_25074971_25075143 0.27 BCAT1
branched chain amino-acid transaminase 1, cytosolic
19048
0.16
chr7_12768879_12769087 0.27 ENSG00000199470
.
28469
0.2
chr7_129995708_129995942 0.26 CPA5
carboxypeptidase A5
7457
0.14
chr8_141954682_141954850 0.26 ENSG00000252864
.
4105
0.27
chr11_57528771_57528928 0.26 CTNND1
catenin (cadherin-associated protein), delta 1
385
0.8
chr3_71592415_71592862 0.26 FOXP1
forkhead box P1
70
0.96
chr19_588658_588919 0.26 HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
1105
0.3
chr2_101728983_101729400 0.26 ENSG00000265860
.
19160
0.19
chr12_46825311_46825703 0.26 SLC38A2
solute carrier family 38, member 2
58857
0.14
chr22_27884822_27884973 0.26 RP11-375H17.1

227571
0.02
chr22_38139115_38139288 0.25 TRIOBP
TRIO and F-actin binding protein
3034
0.16
chr11_13162108_13162259 0.25 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
136016
0.05
chr2_122242346_122242497 0.25 CLASP1
cytoplasmic linker associated protein 1
5483
0.24
chr8_21989039_21989190 0.25 HR
hair growth associated
267
0.85
chr21_39850220_39850518 0.25 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
19976
0.28
chr1_16466515_16466919 0.25 RP11-276H7.2

14989
0.11
chr3_196750502_196750801 0.25 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
6007
0.19
chr3_42085911_42086330 0.25 TRAK1
trafficking protein, kinesin binding 1
46442
0.16
chr3_18140205_18140557 0.24 RP11-158G18.1

310746
0.01
chr5_73611648_73611799 0.24 ENSG00000244326
.
2088
0.42
chr1_162359766_162359944 0.24 C1orf226
chromosome 1 open reading frame 226
8335
0.12
chr16_53822990_53823141 0.24 FTO
fat mass and obesity associated
84971
0.09
chr19_18364497_18364688 0.24 PDE4C
phosphodiesterase 4C, cAMP-specific
1637
0.23
chr2_47313454_47313781 0.23 AC073283.7

18656
0.18
chr8_69244650_69244960 0.23 RP11-664D7.4
HCG1787533; Uncharacterized protein
1079
0.45
chr14_31559795_31560006 0.23 AP4S1
adaptor-related protein complex 4, sigma 1 subunit
24398
0.15
chr18_46775674_46776034 0.23 DYM
dymeclin
8924
0.23
chr15_90233678_90233930 0.23 PEX11A
peroxisomal biogenesis factor 11 alpha
89
0.68
chr7_41745636_41745841 0.23 AC005027.3

805
0.63
chr19_18491287_18491451 0.23 GDF15
growth differentiation factor 15
1611
0.2
chr11_75735939_75736309 0.23 UVRAG
UV radiation resistance associated
41644
0.15
chr3_9006994_9007145 0.23 RAD18
RAD18 homolog (S. cerevisiae)
1612
0.41
chr8_78478320_78478688 0.23 ENSG00000222334
.
279452
0.02
chr22_31479008_31479415 0.23 RP3-412A9.16

340
0.68
chr14_69421781_69422763 0.23 ACTN1
actinin, alpha 1
8007
0.23
chr14_73713964_73714115 0.23 ENSG00000252839
.
451
0.7
chr9_37998944_37999499 0.23 ENSG00000251745
.
62456
0.11
chr17_75361709_75362043 0.23 SEPT9
septin 9
7396
0.18
chr3_23918662_23918822 0.23 RPL15
ribosomal protein L15
39294
0.13
chr11_1913396_1913650 0.23 C11orf89
chromosome 11 open reading frame 89
1439
0.25
chr5_177676308_177676676 0.23 PHYKPL
5-phosphohydroxy-L-lysine phospho-lyase
16706
0.19
chr22_46404101_46404436 0.23 WNT7B
wingless-type MMTV integration site family, member 7B
31259
0.1
chr3_49384271_49384510 0.22 USP4
ubiquitin specific peptidase 4 (proto-oncogene)
6886
0.11
chr2_9427415_9427711 0.22 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
80669
0.1
chr7_47446099_47446250 0.22 TNS3
tensin 3
46655
0.2
chr3_43810178_43810362 0.22 ABHD5
abhydrolase domain containing 5
57071
0.15
chr2_26981757_26981908 0.22 SLC35F6
solute carrier family 35, member F6
5324
0.2
chr1_26217257_26217408 0.22 ENSG00000207302
.
13345
0.08
chr5_139601602_139601854 0.22 CTB-131B5.2

21980
0.13
chr18_32229938_32230237 0.22 DTNA
dystrobrevin, alpha
29414
0.24
chr15_82469698_82469948 0.22 ENSG00000212170
.
3097
0.28
chr12_6643029_6643180 0.22 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
11
0.85
chr1_211433518_211433965 0.22 RCOR3
REST corepressor 3
424
0.87
chr10_98976859_98977010 0.22 SLIT1
slit homolog 1 (Drosophila)
31257
0.14
chr2_151477648_151477907 0.21 RND3
Rho family GTPase 3
82252
0.12
chr4_129768306_129768457 0.21 JADE1
jade family PHD finger 1
15793
0.28
chr15_40536086_40536237 0.21 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
3315
0.14
chr12_46465588_46465739 0.21 SCAF11
SR-related CTD-associated factor 11
79760
0.11
chr6_163777027_163777374 0.21 QKI
QKI, KH domain containing, RNA binding
58475
0.16
chr16_2198362_2198540 0.21 RAB26
RAB26, member RAS oncogene family
174
0.83
chr1_205920578_205920729 0.21 SLC26A9
solute carrier family 26 (anion exchanger), member 9
8065
0.21
chr7_105709201_105709352 0.21 SYPL1
synaptophysin-like 1
29032
0.21
chr17_38178972_38179123 0.21 MED24
mediator complex subunit 24
366
0.78
chr1_202251446_202251597 0.21 ENSG00000239046
.
50729
0.1
chr20_39861758_39862098 0.21 ZHX3
zinc fingers and homeoboxes 3
29247
0.18
chr8_97803430_97803993 0.21 CPQ
carboxypeptidase Q
30243
0.25
chr9_111826033_111826184 0.21 ENSG00000207698
.
17530
0.14
chr17_46560355_46560520 0.21 ENSG00000206805
.
3978
0.15
chr1_174758949_174759102 0.21 RABGAP1L
RAB GTPase activating protein 1-like
10045
0.28
chr1_31574214_31574369 0.21 PUM1
pumilio RNA-binding family member 1
35453
0.17
chr3_37988212_37988363 0.21 CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
17783
0.15
chr4_157884715_157884866 0.21 PDGFC
platelet derived growth factor C
7265
0.23
chr9_116383050_116383201 0.21 RGS3
regulator of G-protein signaling 3
27359
0.19
chr19_12902017_12902168 0.21 JUNB
jun B proto-oncogene
218
0.81
chr11_57123702_57124132 0.21 ENSG00000266018
.
3279
0.12
chr3_117716057_117716400 0.20 LSAMP
limbic system-associated membrane protein
133
0.98
chr3_66499792_66500068 0.20 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
51426
0.17
chr22_19161927_19162579 0.20 AC004463.6

3345
0.15
chr17_62196110_62196316 0.20 ERN1
endoplasmic reticulum to nucleus signaling 1
11272
0.16
chr22_46402793_46403252 0.20 WNT7B
wingless-type MMTV integration site family, member 7B
30013
0.1
chr5_176965550_176965701 0.20 FAM193B
family with sequence similarity 193, member B
727
0.52
chr14_105147633_105147901 0.20 ENSG00000265291
.
3681
0.16
chr15_101986013_101986263 0.20 PCSK6
proprotein convertase subtilisin/kexin type 6
2270
0.39
chr3_42077345_42077717 0.20 TRAK1
trafficking protein, kinesin binding 1
55031
0.14
chr1_173159483_173159962 0.20 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
14975
0.26
chr3_100618907_100619221 0.20 ABI3BP
ABI family, member 3 (NESH) binding protein
14244
0.25
chr14_58748062_58749029 0.20 RP11-349A22.5

5196
0.12
chr1_206713627_206713778 0.20 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
16791
0.15
chr2_46370239_46370448 0.20 AC017006.3

24774
0.22
chr15_85457860_85458027 0.20 ENSG00000207037
.
23810
0.13
chr2_1597634_1597785 0.20 AC144450.1

26176
0.23
chr9_127541109_127541454 0.20 OLFML2A
olfactomedin-like 2A
1731
0.28
chr1_33925705_33926114 0.20 ZSCAN20
zinc finger and SCAN domain containing 20
12337
0.17
chr10_72424330_72424481 0.20 ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
8154
0.25
chr1_214618510_214618915 0.20 PTPN14
protein tyrosine phosphatase, non-receptor type 14
19434
0.26
chr12_71833733_71833884 0.20 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
5
0.98
chr22_42232265_42232534 0.20 RP5-821D11.7

1730
0.24
chr12_121551768_121551919 0.20 ENSG00000201945
.
6997
0.18
chr8_105599662_105599940 0.20 LRP12
low density lipoprotein receptor-related protein 12
1433
0.43
chr4_157700524_157700675 0.20 RP11-154F14.2

61912
0.13
chr10_101469768_101470055 0.20 COX15
cytochrome c oxidase assembly homolog 15 (yeast)
21946
0.14
chr3_131262586_131262737 0.20 RP11-517B11.4

25986
0.18
chr4_84607156_84607307 0.20 ENSG00000201633
.
49788
0.18
chr8_28557924_28558130 0.20 EXTL3-AS1
EXTL3 antisense RNA 1
20
0.95
chr10_21799067_21799308 0.20 SKIDA1
SKI/DACH domain containing 1
7661
0.13
chr1_27855366_27855678 0.19 RP1-159A19.4

3206
0.23
chr3_47203435_47204414 0.19 SETD2
SET domain containing 2
1142
0.44
chr5_56467993_56468852 0.19 GPBP1
GC-rich promoter binding protein 1
1353
0.47
chr14_71878577_71878728 0.19 ENSG00000207444
.
13598
0.23
chr1_152022964_152023546 0.19 S100A11
S100 calcium binding protein A11
13744
0.14
chr19_40917025_40917176 0.19 PRX
periaxin
2171
0.17
chr17_78801110_78801319 0.19 RP11-28G8.1

21782
0.2
chr10_102124571_102124984 0.19 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
17896
0.13
chr10_95236634_95236862 0.19 MYOF
myoferlin
5203
0.21
chr14_35838262_35838413 0.19 NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
35009
0.18
chr1_8931641_8932436 0.19 ENO1-IT1
ENO1 intronic transcript 1 (non-protein coding)
6028
0.14
chr5_14186957_14187108 0.19 TRIO
trio Rho guanine nucleotide exchange factor
3125
0.41
chr16_85406554_85407024 0.19 RP11-680G10.1
Uncharacterized protein
15720
0.23
chr21_44877468_44877619 0.19 SIK1
salt-inducible kinase 1
30535
0.22
chr9_131675686_131675837 0.19 PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
7413
0.12
chr1_974711_974945 0.19 AGRN
agrin
11108
0.08
chr8_96235521_96235672 0.19 C8orf37
chromosome 8 open reading frame 37
45833
0.16
chr22_20886096_20886271 0.19 MED15
mediator complex subunit 15
7621
0.12
chr1_207198601_207198841 0.19 C1orf116
chromosome 1 open reading frame 116
7371
0.14
chr2_17776047_17776198 0.19 VSNL1
visinin-like 1
53695
0.15
chr2_99525996_99526176 0.19 KIAA1211L
KIAA1211-like
1102
0.61
chr6_16681395_16681795 0.19 RP1-151F17.1

79774
0.1
chr2_224680140_224680291 0.19 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
21986
0.25
chr2_36566234_36566385 0.19 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
16760
0.29
chr9_131312108_131312259 0.19 RP11-216B9.6

2506
0.16
chr11_72182622_72182831 0.19 CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
37034
0.13
chr9_137443475_137443828 0.19 COL5A1
collagen, type V, alpha 1
89969
0.08
chr1_55316145_55316296 0.19 DHCR24
24-dehydrocholesterol reductase
3619
0.18
chr12_96629440_96629591 0.19 RP11-394J1.2

11764
0.2
chr12_26790030_26790181 0.18 RP11-666F17.1

13803
0.28
chr2_61176487_61176638 0.18 ENSG00000201076
.
38124
0.13
chr17_48125226_48125421 0.18 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
8016
0.14
chr3_72368118_72368657 0.18 ENSG00000212070
.
56808
0.16
chr2_69034764_69034964 0.18 ARHGAP25
Rho GTPase activating protein 25
501
0.82
chr5_1564026_1564340 0.18 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
15512
0.2
chr11_67776489_67776640 0.18 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
516
0.66
chr6_18276971_18277268 0.18 ENSG00000199715
.
3622
0.22
chr15_45475820_45475971 0.18 SHF
Src homology 2 domain containing F
2490
0.16
chr1_1308946_1309097 0.18 AURKAIP1
aurora kinase A interacting protein 1
1516
0.17
chr19_4376907_4377058 0.18 SH3GL1
SH3-domain GRB2-like 1
3307
0.1
chr15_90755314_90755522 0.18 SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
9564
0.12
chr20_4022392_4022773 0.18 RNF24
ring finger protein 24
26353
0.17
chr2_114734263_114734750 0.18 ENSG00000215984
.
13167
0.22
chr3_172025154_172025305 0.18 AC092964.2
Uncharacterized protein
5543
0.23
chr2_69198318_69198469 0.18 GKN1
gastrokine 1
3312
0.24
chr6_139690937_139691976 0.18 CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
3894
0.32
chr2_106026554_106026715 0.18 FHL2
four and a half LIM domains 2
10510
0.21
chr11_74494315_74495146 0.18 ENSG00000264095
.
30101
0.12
chr8_59746742_59746914 0.18 ENSG00000201231
.
19717
0.27
chr10_48180819_48181165 0.18 AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
8620
0.19
chr10_106110579_106111072 0.18 CCDC147-AS1
CCDC147 antisense RNA 1 (head to head)
2508
0.19
chr3_127468992_127469231 0.18 MGLL
monoglyceride lipase
13911
0.23
chr13_49877691_49877842 0.18 CAB39L
calcium binding protein 39-like
47497
0.14
chr11_112193182_112193453 0.18 ENSG00000206772
.
30068
0.14
chr5_6506361_6506512 0.18 UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
57700
0.15
chr5_9545281_9545432 0.18 SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
831
0.6
chr2_237640623_237640774 0.18 ACKR3
atypical chemokine receptor 3
162414
0.04
chr10_93869895_93870086 0.18 ENSG00000252993
.
33991
0.16
chr14_85999126_85999357 0.18 FLRT2
fibronectin leucine rich transmembrane protein 2
2669
0.33
chr11_10696838_10697077 0.18 MRVI1
murine retrovirus integration site 1 homolog
18104
0.17
chr6_44537708_44537867 0.18 ENSG00000266619
.
134409
0.05
chr22_32025367_32025527 0.18 PISD
phosphatidylserine decarboxylase
479
0.82
chr7_94286288_94286555 0.18 PEG10
paternally expressed 10
739
0.49
chr5_14168529_14168851 0.18 TRIO
trio Rho guanine nucleotide exchange factor
15217
0.3
chr7_50782493_50782644 0.18 GRB10
growth factor receptor-bound protein 10
3964
0.34
chr17_49134950_49135182 0.18 SPAG9
sperm associated antigen 9
10827
0.17
chr1_220473543_220473841 0.18 RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
27896
0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.2 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.2 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0009629 response to gravity(GO:0009629)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.1 GO:0060433 bronchus development(GO:0060433)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.2 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0071071 regulation of phospholipid biosynthetic process(GO:0071071)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0003308 regulation of Wnt signaling pathway involved in heart development(GO:0003307) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0072239 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.0 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0044319 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.2 GO:0007431 salivary gland development(GO:0007431)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0061043 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0035272 exocrine system development(GO:0035272)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0070633 transepithelial transport(GO:0070633)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.2 GO:0019098 mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:1901722 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) cell proliferation involved in metanephros development(GO:0072203) regulation of cell proliferation involved in kidney development(GO:1901722)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.2 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.0 GO:0046475 phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.1 GO:0010894 negative regulation of steroid biosynthetic process(GO:0010894)
0.0 0.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.0 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:0021604 facial nerve development(GO:0021561) rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0 0.0 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0009651 response to salt stress(GO:0009651)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0046184 aldehyde biosynthetic process(GO:0046184)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.0 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0043526 obsolete neuroprotection(GO:0043526)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.0 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946) regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.0 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0010092 specification of organ identity(GO:0010092)
0.0 0.1 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.0 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:2001235 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.0 GO:0032329 serine transport(GO:0032329)
0.0 0.0 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0030992 intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.6 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0016248 channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0015145 monosaccharide transmembrane transporter activity(GO:0015145)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 1.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.0 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism