Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HIC1

Z-value: 1.31

Motif logo

Transcription factors associated with HIC1

Gene Symbol	Gene ID	Gene Info
HIC1 Ensembl NCBI GeneCards UniProt	ENSG00000177374.8	HIC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
HIC1	chr17_1957170_1957392	167	0.881236	0.79	1.2e-02	Click!
HIC1	chr17_1962756_1962907	3227	0.113234	0.77	1.5e-02	Click!
HIC1	chr17_1963661_1963812	4132	0.101828	0.70	3.6e-02	Click!
HIC1	chr17_1974773_1974924	15244	0.084537	0.68	4.4e-02	Click!
HIC1	chr17_1973682_1973833	14153	0.085005	-0.66	5.2e-02	Click!

Activity of the HIC1 motif across conditions

Conditions sorted by the z-value of the HIC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_123301508_123301659	0.43	AP000783.1	Uncharacterized protein	525	0.83
chr8_145598133_145598292	0.39	ADCK5	aarF domain containing kinase 5	462	0.57
chr15_101499460_101499680	0.35	LRRK1	leucine-rich repeat kinase 1	40020	0.15
chr17_79297430_79297605	0.33	TMEM105	transmembrane protein 105	6698	0.14
chr11_126242895_126243350	0.33	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	17253	0.15
chr22_46287916_46288067	0.33	WNT7B	wingless-type MMTV integration site family, member 7B	80604	0.07
chr10_79470908_79471170	0.31	ENSG00000199664	.	65774	0.1
chr8_142120178_142120491	0.31	DENND3	DENN/MADD domain containing 3	7043	0.22
chr3_15373334_15373485	0.30	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	658	0.64
chr12_96588798_96589434	0.30	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	724	0.7
chr5_72921550_72921718	0.30	ARHGEF28	Rho guanine nucleotide exchange factor (GEF) 28	349	0.89
chr11_46259555_46259706	0.30	CTD-2589M5.4		36468	0.14
chr19_34895303_34895698	0.29	PDCD2L	programmed cell death 2-like	211	0.9
chr6_105627463_105627645	0.29	POPDC3	popeye domain containing 3	181	0.92
chr4_187112479_187112630	0.28	AC110771.1	Uncharacterized protein	72	0.56
chr1_156084644_156084795	0.27	LMNA	lamin A/C	206	0.89
chr10_91597567_91597772	0.27	KIF20B	kinesin family member 20B	136233	0.05
chr17_5014893_5015044	0.27	ZNF232	zinc finger protein 232	168	0.53
chr19_38183197_38183429	0.26	ZFP30	ZFP30 zinc finger protein	75	0.51
chr22_43390991_43391142	0.26	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	7380	0.22
chr5_142784532_142784876	0.26	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	184	0.97
chr2_149403364_149403515	0.26	EPC2	enhancer of polycomb homolog 2 (Drosophila)	450	0.9
chr7_150020672_150020823	0.26	ACTR3C	ARP3 actin-related protein 3 homolog C (yeast)	11	0.84
chr1_181056660_181057120	0.25	IER5	immediate early response 5	748	0.71
chr8_142219061_142219212	0.25	DENND3	DENN/MADD domain containing 3	16706	0.15
chr18_12911957_12912108	0.25	PTPN2	protein tyrosine phosphatase, non-receptor type 2	17610	0.19
chr10_121302384_121302535	0.25	RGS10	regulator of G-protein signaling 10	239	0.95
chr7_139875650_139875801	0.25	KDM7A	lysine (K)-specific demethylase 7A	1016	0.41
chr4_142558013_142558295	0.25	IL15	interleukin 15	54	0.99
chr16_70414920_70415071	0.25	RP11-529K1.4		1635	0.26
chr17_19265786_19266015	0.24	B9D1	B9 protein domain 1	11	0.96
chr5_134871706_134871930	0.24	NEUROG1	neurogenin 1	179	0.95
chr14_64320021_64320383	0.24	SYNE2	spectrin repeat containing, nuclear envelope 2	470	0.83
chr16_57513363_57513621	0.24	DOK4	docking protein 4	225	0.9
chr17_79019370_79019521	0.24	BAIAP2	BAI1-associated protein 2	7717	0.13
chr16_11517843_11518143	0.24	CTD-3088G3.8	Protein LOC388210	25627	0.11
chr22_39688482_39688637	0.24	RP3-333H23.8		434	0.73
chr3_185531495_185531680	0.24	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	7262	0.24
chr11_62554232_62554383	0.24	RP11-727F15.12		50	0.86
chr3_169386259_169386493	0.24	MECOM	MDS1 and EVI1 complex locus	5118	0.19
chr17_4891121_4891272	0.23	RP5-1050D4.5		195	0.5
chr14_65016574_65016725	0.23	PPP1R36	protein phosphatase 1, regulatory subunit 36	29	0.96
chr2_113915138_113915289	0.23	PSD4	pleckstrin and Sec7 domain containing 4	16335	0.13
chr9_139538749_139539009	0.23	EGFL7	EGF-like-domain, multiple 7	14429	0.09
chr8_81490427_81490652	0.23	ENSG00000223327	.	7469	0.23
chr15_66914780_66915271	0.23	RP11-321F6.1	HCG2003567; Uncharacterized protein	40497	0.12
chr14_101588217_101588492	0.23	ENSG00000206761	.	23678	0.04
chr4_1728974_1729134	0.23	TACC3	transforming, acidic coiled-coil containing protein 3	1077	0.43
chr13_24153750_24153949	0.23	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	330	0.93
chr9_135117273_135117424	0.23	ENSG00000221105	.	27086	0.2
chr19_36822233_36822591	0.22	ENSG00000222730	.	1061	0.46
chr5_139127106_139127386	0.22	ENSG00000200756	.	29571	0.16
chr9_96919191_96919602	0.22	ENSG00000199165	.	18838	0.15
chr10_80886709_80887280	0.22	ZMIZ1	zinc finger, MIZ-type containing 1	58202	0.14
chr11_46354904_46355055	0.22	DGKZ	diacylglycerol kinase, zeta	524	0.74
chr22_43328839_43329007	0.22	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	12956	0.22
chr1_12678566_12678717	0.22	DHRS3	dehydrogenase/reductase (SDR family) member 3	904	0.57
chr6_219821_220028	0.22	DUSP22	dual specificity phosphatase 22	71706	0.13
chr14_65321384_65321594	0.22	SPTB	spectrin, beta, erythrocytic	25066	0.14
chr22_20849650_20849801	0.22	KLHL22	kelch-like family member 22	357	0.53
chr11_74460077_74460228	0.22	RNF169	ring finger protein 169	239	0.89
chr3_77087795_77087946	0.22	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	1167	0.63
chr15_70556363_70556608	0.22	ENSG00000200216	.	70910	0.13
chr8_1949218_1949470	0.22	KBTBD11	kelch repeat and BTB (POZ) domain containing 11	27300	0.21
chr13_33923903_33924198	0.22	STARD13	StAR-related lipid transfer (START) domain containing 13	711	0.73
chr8_59058998_59059219	0.22	FAM110B	family with sequence similarity 110, member B	151995	0.04
chr17_17684994_17685191	0.21	RAI1	retinoic acid induced 1	354	0.78
chr10_76513880_76514031	0.21	KAT6B	K(lysine) acetyltransferase 6B	71385	0.12
chr3_67704618_67704769	0.21	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	338	0.94
chr3_142840251_142840402	0.21	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	2153	0.37
chr5_17402468_17402619	0.21	ENSG00000201715	.	56818	0.16
chr11_64611961_64612112	0.21	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	5	0.96
chr3_9885063_9885214	0.21	RPUSD3	RNA pseudouridylate synthase domain containing 3	488	0.64
chr3_176938963_176939114	0.21	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	23777	0.24
chr22_38136040_38136191	0.21	TRIOBP	TRIO and F-actin binding protein	6120	0.13
chr8_144479919_144480248	0.21	RP11-909N17.2		14836	0.09
chr3_12329938_12330144	0.21	PPARG	peroxisome proliferator-activated receptor gamma	296	0.94
chr4_2420730_2420881	0.21	ZFYVE28	zinc finger, FYVE domain containing 28	415	0.83
chr17_79093173_79093330	0.21	ENSG00000207736	.	5922	0.1
chr11_118305737_118305934	0.21	RP11-770J1.4		86	0.93
chr19_7566190_7566368	0.21	C19orf45	chromosome 19 open reading frame 45	1751	0.19
chr9_132500262_132500413	0.21	PTGES	prostaglandin E synthase	14989	0.14
chr3_39425504_39425655	0.21	SLC25A38	solute carrier family 25, member 38	699	0.61
chr8_22722343_22722494	0.21	RP11-87E22.2		13067	0.17
chr13_37248035_37248273	0.21	SERTM1	serine-rich and transmembrane domain containing 1	105	0.98
chr10_105001357_105001535	0.20	RPEL1	ribulose-5-phosphate-3-epimerase-like 1	4198	0.21
chr7_156813832_156814124	0.20	MNX1-AS1	MNX1 antisense RNA 1 (head to head)	10479	0.16
chr14_67999817_67999968	0.20	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	126	0.86
chr19_1401163_1401383	0.20	GAMT	guanidinoacetate N-methyltransferase	269	0.78
chr12_48340201_48340352	0.20	VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	3445	0.2
chr20_32255046_32255197	0.20	NECAB3	N-terminal EF-hand calcium binding protein 3	656	0.4
chr7_76026926_76027201	0.20	ZP3	zona pellucida glycoprotein 3 (sperm receptor)	228	0.92
chr14_55033500_55033670	0.20	SAMD4A	sterile alpha motif domain containing 4A	230	0.95
chr11_450644_450873	0.20	PTDSS2	phosphatidylserine synthase 2	478	0.63
chr14_91124792_91125085	0.20	TTC7B	tetratricopeptide repeat domain 7B	14386	0.16
chr22_46403312_46403647	0.20	WNT7B	wingless-type MMTV integration site family, member 7B	30470	0.1
chr1_205638546_205638697	0.20	SLC45A3	solute carrier family 45, member 3	10966	0.15
chr4_1729881_1730032	0.20	TACC3	transforming, acidic coiled-coil containing protein 3	175	0.93
chr5_178487503_178487654	0.20	ZNF354C	zinc finger protein 354C	162	0.96
chr8_22604778_22604955	0.20	ENSG00000253125	.	150	0.96
chr4_109683560_109683768	0.20	ETNPPL	ethanolamine-phosphate phospho-lyase	27	0.98
chr16_57660984_57661135	0.19	GPR56	G protein-coupled receptor 56	564	0.69
chr8_22560866_22561017	0.19	EGR3	early growth response 3	10126	0.13
chr6_143268405_143268556	0.19	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	2142	0.4
chr2_102680238_102680787	0.19	IL1R1	interleukin 1 receptor, type I	492	0.85
chr22_36853951_36854133	0.19	ENSG00000252225	.	17027	0.13
chr1_19638140_19638327	0.19	AKR7A2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	168	0.81
chr6_139350062_139350213	0.19	ABRACL	ABRA C-terminal like	158	0.97
chr20_13976641_13976793	0.19	MACROD2	MACRO domain containing 2	307	0.55
chr15_70440007_70440428	0.19	ENSG00000200216	.	45358	0.16
chr11_4208528_4208828	0.19	RRM1-AS1	RRM1 antisense RNA 1	49191	0.14
chr22_50618466_50618746	0.19	TRABD	TraB domain containing	5738	0.09
chr10_80725065_80725216	0.19	ZMIZ1-AS1	ZMIZ1 antisense RNA 1	2989	0.39
chr10_73847993_73848144	0.19	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	18	0.98
chr3_186078642_186078793	0.19	DGKG	diacylglycerol kinase, gamma 90kDa	1029	0.66
chr1_51435046_51435197	0.19	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	495	0.82
chr2_112895757_112895915	0.19	FBLN7	fibulin 7	126	0.97
chr17_25893405_25893556	0.19	KSR1	kinase suppressor of ras 1	16467	0.2
chr22_50913528_50913679	0.19	SBF1	SET binding factor 1	149	0.9
chr2_211089697_211089892	0.19	ACADL	acyl-CoA dehydrogenase, long chain	421	0.83
chr12_120763625_120763877	0.18	PLA2G1B	phospholipase A2, group IB (pancreas)	145	0.93
chr11_46259289_46259440	0.18	CTD-2589M5.4		36734	0.14
chr19_18575570_18575881	0.18	ELL	elongation factor RNA polymerase II	11018	0.1
chr6_107440312_107440463	0.18	BEND3	BEN domain containing 3	3914	0.26
chr19_949007_949193	0.18	ARID3A	AT rich interactive domain 3A (BRIGHT-like)	16591	0.07
chr13_42032226_42032428	0.18	RGCC	regulator of cell cycle	632	0.67
chr6_35420284_35420435	0.18	FANCE	Fanconi anemia, complementation group E	221	0.93
chr5_785429_785580	0.18	ZDHHC11B	zinc finger, DHHC-type containing 11B	18437	0.18
chr5_141348457_141348608	0.18	RNF14	ring finger protein 14	72	0.96
chr3_58652897_58653052	0.18	FAM3D	family with sequence similarity 3, member D	399	0.87
chr20_31045349_31045530	0.18	RP5-1184F4.5		7881	0.18
chr14_24867552_24867703	0.18	NYNRIN	NYN domain and retroviral integrase containing	365	0.75
chr16_1980217_1980428	0.18	HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	11881	0.06
chr8_134308968_134309186	0.18	NDRG1	N-myc downstream regulated 1	258	0.95
chr11_315885_316036	0.18	IFITM1	interferon induced transmembrane protein 1	2107	0.12
chr12_120426741_120426892	0.18	CCDC64	coiled-coil domain containing 64	857	0.66
chr14_103557693_103557921	0.18	RP11-736N17.8		3253	0.21
chr7_129912749_129913103	0.18	CPA2	carboxypeptidase A2 (pancreatic)	6259	0.15
chr9_38622054_38622296	0.18	FAM201A	family with sequence similarity 201, member A	1090	0.44
chr19_44111918_44112330	0.18	SRRM5	serine/arginine repetitive matrix 5	4129	0.09
chrX_101906739_101906890	0.18	GPRASP1	G protein-coupled receptor associated sorting protein 1	485	0.76
chr17_34842791_34842942	0.18	ZNHIT3	zinc finger, HIT-type containing 3	294	0.85
chr7_48075139_48075366	0.18	C7orf57	chromosome 7 open reading frame 57	135	0.96
chr6_50818677_50818828	0.18	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	32313	0.25
chr2_54667400_54667551	0.18	SPTBN1	spectrin, beta, non-erythrocytic 1	15947	0.24
chr10_103990547_103990698	0.18	PITX3	paired-like homeodomain 3	1218	0.37
chr17_48351036_48351238	0.17	TMEM92	transmembrane protein 92	651	0.61
chr14_61788792_61788943	0.17	PRKCH	protein kinase C, eta	432	0.62
chr13_98795842_98795993	0.17	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	183	0.95
chr19_16571490_16571641	0.17	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	11189	0.12
chr8_134664602_134664753	0.17	ENSG00000212273	.	7709	0.31
chr18_45936153_45936382	0.17	ZBTB7C	zinc finger and BTB domain containing 7C	474	0.84
chr3_128839994_128840145	0.17	RAB43	RAB43, member RAS oncogene family	555	0.64
chr20_57581666_57581817	0.17	CTSZ	cathepsin Z	561	0.7
chr11_13300235_13300386	0.17	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	878	0.72
chr1_45793013_45793296	0.17	HPDL	4-hydroxyphenylpyruvate dioxygenase-like	609	0.67
chr17_17685761_17685912	0.17	RAI1	retinoic acid induced 1	390	0.76
chr10_126749541_126749767	0.17	ENSG00000264572	.	28215	0.18
chr11_57243945_57244096	0.17	RP11-624G17.3		987	0.35
chr15_70873167_70873332	0.17	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	121371	0.06
chr12_107713372_107713523	0.17	BTBD11	BTB (POZ) domain containing 11	228	0.96
chr5_170738876_170739099	0.17	TLX3	T-cell leukemia homeobox 3	2699	0.26
chr17_1655742_1656238	0.17	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	9263	0.1
chr5_172659783_172660057	0.17	NKX2-5	NK2 homeobox 5	2289	0.28
chr15_57591994_57592162	0.17	TCF12	transcription factor 12	17425	0.21
chr10_35069926_35070077	0.17	PARD3	par-3 family cell polarity regulator	34248	0.18
chr20_61087234_61087385	0.17	GATA5	GATA binding protein 5	36283	0.11
chr6_143998810_143998977	0.17	PHACTR2	phosphatase and actin regulator 2	209	0.96
chr22_31741186_31741337	0.17	PATZ1	POZ (BTB) and AT hook containing zinc finger 1	501	0.64
chr4_7057020_7057288	0.17	TADA2B	transcriptional adaptor 2B	2074	0.21
chr22_46973599_46973750	0.17	GRAMD4	GRAM domain containing 4	648	0.75
chrX_69653934_69654085	0.17	DLG3	discs, large homolog 3 (Drosophila)	10702	0.14
chr19_6243165_6243316	0.17	CTC-503J8.4		15928	0.14
chr11_7534597_7534748	0.17	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	143	0.91
chr5_159107_159571	0.17	ENSG00000199540	.	15027	0.14
chr3_46185448_46185808	0.17	CCR3	chemokine (C-C motif) receptor 3	19468	0.21
chr15_83316548_83316788	0.16	CPEB1	cytoplasmic polyadenylation element binding protein 1	60	0.62
chr17_7486608_7486759	0.16	AC113189.5		153	0.47
chr11_126233884_126234182	0.16	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	8164	0.16
chr10_92922156_92922510	0.16	PCGF5	polycomb group ring finger 5	57575	0.16
chr17_64299023_64299202	0.16	PRKCA	protein kinase C, alpha	168	0.96
chr1_244012941_244013092	0.16	AKT3	v-akt murine thymoma viral oncogene homolog 3	414	0.89
chr17_68165689_68166035	0.16	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	186	0.66
chr10_94179898_94180049	0.16	ENSG00000207895	.	21088	0.21
chr15_90319837_90320135	0.16	MESP2	mesoderm posterior 2 homolog (mouse)	397	0.79
chr3_55522536_55522942	0.16	WNT5A-AS1	WNT5A antisense RNA 1	1012	0.47
chr2_62592200_62592351	0.16	ENSG00000238809	.	100145	0.07
chr2_231742152_231742309	0.16	AC012507.3		8985	0.17
chr22_20287333_20287484	0.16	XXbac-B444P24.13		18864	0.11
chr2_109745417_109745568	0.16	SH3RF3	SH3 domain containing ring finger 3	312	0.92
chr5_59189611_59189822	0.16	PDE4D	phosphodiesterase 4D, cAMP-specific	91	0.98
chr16_2630606_2630757	0.16	RP11-20I23.7		8327	0.07
chr10_100227678_100227852	0.16	HPS1	Hermansky-Pudlak syndrome 1	21082	0.19
chr12_53465850_53466141	0.16	SPRYD3	SPRY domain containing 3	7166	0.11
chr11_108368869_108369152	0.16	KDELC2	KDEL (Lys-Asp-Glu-Leu) containing 2	149	0.96
chr6_72129499_72129753	0.16	ENSG00000207827	.	16302	0.22
chr10_3306842_3307061	0.16	PITRM1	pitrilysin metallopeptidase 1	91948	0.09
chr8_27695395_27695562	0.16	PBK	PDZ binding kinase	121	0.96
chr21_45585843_45585994	0.16	AP001055.1		7662	0.15
chr15_66914114_66914568	0.16	RP11-321F6.1	HCG2003567; Uncharacterized protein	39813	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.1	0.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.1	0.2	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.3	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.0	0.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.2	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.2	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.2	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0046084	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.2	GO:0031650	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.0	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0044256	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.0	GO:0006560	proline metabolic process(GO:0006560)
0.0	0.1	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.0	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.0	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.2	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0045073	regulation of chemokine biosynthetic process(GO:0045073)
0.0	0.1	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0010224	response to UV-B(GO:0010224)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0044557	relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.2	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.0	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0045588	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0009154	purine ribonucleotide catabolic process(GO:0009154)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.0	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989) low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.2	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.2	GO:0048260	positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.6	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0032190	acrosin binding(GO:0032190)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0032142	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.4	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099) L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.5	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.2	GO:0016248	channel inhibitor activity(GO:0016248)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.0	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.0	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets