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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HIC1

Z-value: 1.31

Motif logo

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Transcription factors associated with HIC1

Gene Symbol Gene ID Gene Info
HIC1
ENSG00000177374.8 HIC ZBTB transcriptional repressor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_1957170_1957392HIC11670.8812360.791.2e-02Click!
chr17_1962756_1962907HIC132270.1132340.771.5e-02Click!
chr17_1963661_1963812HIC141320.1018280.703.6e-02Click!
chr17_1974773_1974924HIC1152440.0845370.684.4e-02Click!
chr17_1973682_1973833HIC1141530.085005-0.665.2e-02Click!

Activity of the HIC1 motif across conditions

Conditions sorted by the z-value of the HIC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_123301508_123301659 0.43 AP000783.1
 Uncharacterized protein
 525
 0.83
chr8_145598133_145598292 0.39 ADCK5
 aarF domain containing kinase 5
 462
 0.57
chr15_101499460_101499680 0.35 LRRK1
 leucine-rich repeat kinase 1
 40020
 0.15
chr17_79297430_79297605 0.33 TMEM105
 transmembrane protein 105
 6698
 0.14
chr11_126242895_126243350 0.33 ST3GAL4
 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
 17253
 0.15
chr22_46287916_46288067 0.33 WNT7B
 wingless-type MMTV integration site family, member 7B
 80604
 0.07
chr10_79470908_79471170 0.31 ENSG00000199664
 .
 65774
 0.1
chr8_142120178_142120491 0.31 DENND3
 DENN/MADD domain containing 3
 7043
 0.22
chr3_15373334_15373485 0.30 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 658
 0.64
chr12_96588798_96589434 0.30 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 724
 0.7
chr5_72921550_72921718 0.30 ARHGEF28
 Rho guanine nucleotide exchange factor (GEF) 28
 349
 0.89
chr11_46259555_46259706 0.30 CTD-2589M5.4
36468
 0.14
chr19_34895303_34895698 0.29 PDCD2L
 programmed cell death 2-like
 211
 0.9
chr6_105627463_105627645 0.29 POPDC3
 popeye domain containing 3
 181
 0.92
chr4_187112479_187112630 0.28 AC110771.1
 Uncharacterized protein
 72
 0.56
chr1_156084644_156084795 0.27 LMNA
 lamin A/C
 206
 0.89
chr10_91597567_91597772 0.27 KIF20B
 kinesin family member 20B
 136233
 0.05
chr17_5014893_5015044 0.27 ZNF232
 zinc finger protein 232
 168
 0.53
chr19_38183197_38183429 0.26 ZFP30
 ZFP30 zinc finger protein
 75
 0.51
chr22_43390991_43391142 0.26 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 7380
 0.22
chr5_142784532_142784876 0.26 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
 184
 0.97
chr2_149403364_149403515 0.26 EPC2
 enhancer of polycomb homolog 2 (Drosophila)
 450
 0.9
chr7_150020672_150020823 0.26 ACTR3C
 ARP3 actin-related protein 3 homolog C (yeast)
 11
 0.84
chr1_181056660_181057120 0.25 IER5
 immediate early response 5
 748
 0.71
chr8_142219061_142219212 0.25 DENND3
 DENN/MADD domain containing 3
 16706
 0.15
chr18_12911957_12912108 0.25 PTPN2
 protein tyrosine phosphatase, non-receptor type 2
 17610
 0.19
chr10_121302384_121302535 0.25 RGS10
 regulator of G-protein signaling 10
 239
 0.95
chr7_139875650_139875801 0.25 KDM7A
 lysine (K)-specific demethylase 7A
 1016
 0.41
chr4_142558013_142558295 0.25 IL15
 interleukin 15
 54
 0.99
chr16_70414920_70415071 0.25 RP11-529K1.4
1635
 0.26
chr17_19265786_19266015 0.24 B9D1
 B9 protein domain 1
 11
 0.96
chr5_134871706_134871930 0.24 NEUROG1
 neurogenin 1
 179
 0.95
chr14_64320021_64320383 0.24 SYNE2
 spectrin repeat containing, nuclear envelope 2
 470
 0.83
chr16_57513363_57513621 0.24 DOK4
 docking protein 4
 225
 0.9
chr17_79019370_79019521 0.24 BAIAP2
 BAI1-associated protein 2
 7717
 0.13
chr16_11517843_11518143 0.24 CTD-3088G3.8
 Protein LOC388210
 25627
 0.11
chr22_39688482_39688637 0.24 RP3-333H23.8
434
 0.73
chr3_185531495_185531680 0.24 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
 7262
 0.24
chr11_62554232_62554383 0.24 RP11-727F15.12
50
 0.86
chr3_169386259_169386493 0.24 MECOM
 MDS1 and EVI1 complex locus
 5118
 0.19
chr17_4891121_4891272 0.23 RP5-1050D4.5
195
 0.5
chr14_65016574_65016725 0.23 PPP1R36
 protein phosphatase 1, regulatory subunit 36
 29
 0.96
chr2_113915138_113915289 0.23 PSD4
 pleckstrin and Sec7 domain containing 4
 16335
 0.13
chr9_139538749_139539009 0.23 EGFL7
 EGF-like-domain, multiple 7
 14429
 0.09
chr8_81490427_81490652 0.23 ENSG00000223327
 .
 7469
 0.23
chr15_66914780_66915271 0.23 RP11-321F6.1
 HCG2003567; Uncharacterized protein
 40497
 0.12
chr14_101588217_101588492 0.23 ENSG00000206761
 .
 23678
 0.04
chr4_1728974_1729134 0.23 TACC3
 transforming, acidic coiled-coil containing protein 3
 1077
 0.43
chr13_24153750_24153949 0.23 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 330
 0.93
chr9_135117273_135117424 0.23 ENSG00000221105
 .
 27086
 0.2
chr19_36822233_36822591 0.22 ENSG00000222730
 .
 1061
 0.46
chr5_139127106_139127386 0.22 ENSG00000200756
 .
 29571
 0.16
chr9_96919191_96919602 0.22 ENSG00000199165
 .
 18838
 0.15
chr10_80886709_80887280 0.22 ZMIZ1
 zinc finger, MIZ-type containing 1
 58202
 0.14
chr11_46354904_46355055 0.22 DGKZ
 diacylglycerol kinase, zeta
 524
 0.74
chr22_43328839_43329007 0.22 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 12956
 0.22
chr1_12678566_12678717 0.22 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 904
 0.57
chr6_219821_220028 0.22 DUSP22
 dual specificity phosphatase 22
 71706
 0.13
chr14_65321384_65321594 0.22 SPTB
 spectrin, beta, erythrocytic
 25066
 0.14
chr22_20849650_20849801 0.22 KLHL22
 kelch-like family member 22
 357
 0.53
chr11_74460077_74460228 0.22 RNF169
 ring finger protein 169
 239
 0.89
chr3_77087795_77087946 0.22 ROBO2
 roundabout, axon guidance receptor, homolog 2 (Drosophila)
 1167
 0.63
chr15_70556363_70556608 0.22 ENSG00000200216
 .
 70910
 0.13
chr8_1949218_1949470 0.22 KBTBD11
 kelch repeat and BTB (POZ) domain containing 11
 27300
 0.21
chr13_33923903_33924198 0.22 STARD13
 StAR-related lipid transfer (START) domain containing 13
 711
 0.73
chr8_59058998_59059219 0.22 FAM110B
 family with sequence similarity 110, member B
 151995
 0.04
chr17_17684994_17685191 0.21 RAI1
 retinoic acid induced 1
 354
 0.78
chr10_76513880_76514031 0.21 KAT6B
 K(lysine) acetyltransferase 6B
 71385
 0.12
chr3_67704618_67704769 0.21 SUCLG2
 succinate-CoA ligase, GDP-forming, beta subunit
 338
 0.94
chr3_142840251_142840402 0.21 CHST2
 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
 2153
 0.37
chr5_17402468_17402619 0.21 ENSG00000201715
 .
 56818
 0.16
chr11_64611961_64612112 0.21 CDC42BPG
 CDC42 binding protein kinase gamma (DMPK-like)
 5
 0.96
chr3_9885063_9885214 0.21 RPUSD3
 RNA pseudouridylate synthase domain containing 3
 488
 0.64
chr3_176938963_176939114 0.21 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 23777
 0.24
chr22_38136040_38136191 0.21 TRIOBP
 TRIO and F-actin binding protein
 6120
 0.13
chr8_144479919_144480248 0.21 RP11-909N17.2
14836
 0.09
chr3_12329938_12330144 0.21 PPARG
 peroxisome proliferator-activated receptor gamma
 296
 0.94
chr4_2420730_2420881 0.21 ZFYVE28
 zinc finger, FYVE domain containing 28
 415
 0.83
chr17_79093173_79093330 0.21 ENSG00000207736
 .
 5922
 0.1
chr11_118305737_118305934 0.21 RP11-770J1.4
86
 0.93
chr19_7566190_7566368 0.21 C19orf45
 chromosome 19 open reading frame 45
 1751
 0.19
chr9_132500262_132500413 0.21 PTGES
 prostaglandin E synthase
 14989
 0.14
chr3_39425504_39425655 0.21 SLC25A38
 solute carrier family 25, member 38
 699
 0.61
chr8_22722343_22722494 0.21 RP11-87E22.2
13067
 0.17
chr13_37248035_37248273 0.21 SERTM1
 serine-rich and transmembrane domain containing 1
 105
 0.98
chr10_105001357_105001535 0.20 RPEL1
 ribulose-5-phosphate-3-epimerase-like 1
 4198
 0.21
chr7_156813832_156814124 0.20 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 10479
 0.16
chr14_67999817_67999968 0.20 PLEKHH1
 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
 126
 0.86
chr19_1401163_1401383 0.20 GAMT
 guanidinoacetate N-methyltransferase
 269
 0.78
chr12_48340201_48340352 0.20 VDR
 vitamin D (1,25- dihydroxyvitamin D3) receptor
 3445
 0.2
chr20_32255046_32255197 0.20 NECAB3
 N-terminal EF-hand calcium binding protein 3
 656
 0.4
chr7_76026926_76027201 0.20 ZP3
 zona pellucida glycoprotein 3 (sperm receptor)
 228
 0.92
chr14_55033500_55033670 0.20 SAMD4A
 sterile alpha motif domain containing 4A
 230
 0.95
chr11_450644_450873 0.20 PTDSS2
 phosphatidylserine synthase 2
 478
 0.63
chr14_91124792_91125085 0.20 TTC7B
 tetratricopeptide repeat domain 7B
 14386
 0.16
chr22_46403312_46403647 0.20 WNT7B
 wingless-type MMTV integration site family, member 7B
 30470
 0.1
chr1_205638546_205638697 0.20 SLC45A3
 solute carrier family 45, member 3
 10966
 0.15
chr4_1729881_1730032 0.20 TACC3
 transforming, acidic coiled-coil containing protein 3
 175
 0.93
chr5_178487503_178487654 0.20 ZNF354C
 zinc finger protein 354C
 162
 0.96
chr8_22604778_22604955 0.20 ENSG00000253125
 .
 150
 0.96
chr4_109683560_109683768 0.20 ETNPPL
 ethanolamine-phosphate phospho-lyase
 27
 0.98
chr16_57660984_57661135 0.19 GPR56
 G protein-coupled receptor 56
 564
 0.69
chr8_22560866_22561017 0.19 EGR3
 early growth response 3
 10126
 0.13
chr6_143268405_143268556 0.19 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 2142
 0.4
chr2_102680238_102680787 0.19 IL1R1
 interleukin 1 receptor, type I
 492
 0.85
chr22_36853951_36854133 0.19 ENSG00000252225
 .
 17027
 0.13
chr1_19638140_19638327 0.19 AKR7A2
 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
 168
 0.81
chr6_139350062_139350213 0.19 ABRACL
 ABRA C-terminal like
 158
 0.97
chr20_13976641_13976793 0.19 MACROD2
 MACRO domain containing 2
 307
 0.55
chr15_70440007_70440428 0.19 ENSG00000200216
 .
 45358
 0.16
chr11_4208528_4208828 0.19 RRM1-AS1
 RRM1 antisense RNA 1
 49191
 0.14
chr22_50618466_50618746 0.19 TRABD
 TraB domain containing
 5738
 0.09
chr10_80725065_80725216 0.19 ZMIZ1-AS1
 ZMIZ1 antisense RNA 1
 2989
 0.39
chr10_73847993_73848144 0.19 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 18
 0.98
chr3_186078642_186078793 0.19 DGKG
 diacylglycerol kinase, gamma 90kDa
 1029
 0.66
chr1_51435046_51435197 0.19 CDKN2C
 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
 495
 0.82
chr2_112895757_112895915 0.19 FBLN7
 fibulin 7
 126
 0.97
chr17_25893405_25893556 0.19 KSR1
 kinase suppressor of ras 1
 16467
 0.2
chr22_50913528_50913679 0.19 SBF1
 SET binding factor 1
 149
 0.9
chr2_211089697_211089892 0.19 ACADL
 acyl-CoA dehydrogenase, long chain
 421
 0.83
chr12_120763625_120763877 0.18 PLA2G1B
 phospholipase A2, group IB (pancreas)
 145
 0.93
chr11_46259289_46259440 0.18 CTD-2589M5.4
36734
 0.14
chr19_18575570_18575881 0.18 ELL
 elongation factor RNA polymerase II
 11018
 0.1
chr6_107440312_107440463 0.18 BEND3
 BEN domain containing 3
 3914
 0.26
chr19_949007_949193 0.18 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
 16591
 0.07
chr13_42032226_42032428 0.18 RGCC
 regulator of cell cycle
 632
 0.67
chr6_35420284_35420435 0.18 FANCE
 Fanconi anemia, complementation group E
 221
 0.93
chr5_785429_785580 0.18 ZDHHC11B
 zinc finger, DHHC-type containing 11B
 18437
 0.18
chr5_141348457_141348608 0.18 RNF14
 ring finger protein 14
 72
 0.96
chr3_58652897_58653052 0.18 FAM3D
 family with sequence similarity 3, member D
 399
 0.87
chr20_31045349_31045530 0.18 RP5-1184F4.5
7881
 0.18
chr14_24867552_24867703 0.18 NYNRIN
 NYN domain and retroviral integrase containing
 365
 0.75
chr16_1980217_1980428 0.18 HS3ST6
 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
 11881
 0.06
chr8_134308968_134309186 0.18 NDRG1
 N-myc downstream regulated 1
 258
 0.95
chr11_315885_316036 0.18 IFITM1
 interferon induced transmembrane protein 1
 2107
 0.12
chr12_120426741_120426892 0.18 CCDC64
 coiled-coil domain containing 64
 857
 0.66
chr14_103557693_103557921 0.18 RP11-736N17.8
3253
 0.21
chr7_129912749_129913103 0.18 CPA2
 carboxypeptidase A2 (pancreatic)
 6259
 0.15
chr9_38622054_38622296 0.18 FAM201A
 family with sequence similarity 201, member A
 1090
 0.44
chr19_44111918_44112330 0.18 SRRM5
 serine/arginine repetitive matrix 5
 4129
 0.09
chrX_101906739_101906890 0.18 GPRASP1
 G protein-coupled receptor associated sorting protein 1
 485
 0.76
chr17_34842791_34842942 0.18 ZNHIT3
 zinc finger, HIT-type containing 3
 294
 0.85
chr7_48075139_48075366 0.18 C7orf57
 chromosome 7 open reading frame 57
 135
 0.96
chr6_50818677_50818828 0.18 TFAP2B
 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
 32313
 0.25
chr2_54667400_54667551 0.18 SPTBN1
 spectrin, beta, non-erythrocytic 1
 15947
 0.24
chr10_103990547_103990698 0.18 PITX3
 paired-like homeodomain 3
 1218
 0.37
chr17_48351036_48351238 0.17 TMEM92
 transmembrane protein 92
 651
 0.61
chr14_61788792_61788943 0.17 PRKCH
 protein kinase C, eta
 432
 0.62
chr13_98795842_98795993 0.17 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
 183
 0.95
chr19_16571490_16571641 0.17 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 11189
 0.12
chr8_134664602_134664753 0.17 ENSG00000212273
 .
 7709
 0.31
chr18_45936153_45936382 0.17 ZBTB7C
 zinc finger and BTB domain containing 7C
 474
 0.84
chr3_128839994_128840145 0.17 RAB43
 RAB43, member RAS oncogene family
 555
 0.64
chr20_57581666_57581817 0.17 CTSZ
 cathepsin Z
 561
 0.7
chr11_13300235_13300386 0.17 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 878
 0.72
chr1_45793013_45793296 0.17 HPDL
 4-hydroxyphenylpyruvate dioxygenase-like
 609
 0.67
chr17_17685761_17685912 0.17 RAI1
 retinoic acid induced 1
 390
 0.76
chr10_126749541_126749767 0.17 ENSG00000264572
 .
 28215
 0.18
chr11_57243945_57244096 0.17 RP11-624G17.3
987
 0.35
chr15_70873167_70873332 0.17 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 121371
 0.06
chr12_107713372_107713523 0.17 BTBD11
 BTB (POZ) domain containing 11
 228
 0.96
chr5_170738876_170739099 0.17 TLX3
 T-cell leukemia homeobox 3
 2699
 0.26
chr17_1655742_1656238 0.17 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 9263
 0.1
chr5_172659783_172660057 0.17 NKX2-5
 NK2 homeobox 5
 2289
 0.28
chr15_57591994_57592162 0.17 TCF12
 transcription factor 12
 17425
 0.21
chr10_35069926_35070077 0.17 PARD3
 par-3 family cell polarity regulator
 34248
 0.18
chr20_61087234_61087385 0.17 GATA5
 GATA binding protein 5
 36283
 0.11
chr6_143998810_143998977 0.17 PHACTR2
 phosphatase and actin regulator 2
 209
 0.96
chr22_31741186_31741337 0.17 PATZ1
 POZ (BTB) and AT hook containing zinc finger 1
 501
 0.64
chr4_7057020_7057288 0.17 TADA2B
 transcriptional adaptor 2B
 2074
 0.21
chr22_46973599_46973750 0.17 GRAMD4
 GRAM domain containing 4
 648
 0.75
chrX_69653934_69654085 0.17 DLG3
 discs, large homolog 3 (Drosophila)
 10702
 0.14
chr19_6243165_6243316 0.17 CTC-503J8.4
15928
 0.14
chr11_7534597_7534748 0.17 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
 143
 0.91
chr5_159107_159571 0.17 ENSG00000199540
 .
 15027
 0.14
chr3_46185448_46185808 0.17 CCR3
 chemokine (C-C motif) receptor 3
 19468
 0.21
chr15_83316548_83316788 0.16 CPEB1
 cytoplasmic polyadenylation element binding protein 1
 60
 0.62
chr17_7486608_7486759 0.16 AC113189.5
153
 0.47
chr11_126233884_126234182 0.16 ST3GAL4
 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
 8164
 0.16
chr10_92922156_92922510 0.16 PCGF5
 polycomb group ring finger 5
 57575
 0.16
chr17_64299023_64299202 0.16 PRKCA
 protein kinase C, alpha
 168
 0.96
chr1_244012941_244013092 0.16 AKT3
 v-akt murine thymoma viral oncogene homolog 3
 414
 0.89
chr17_68165689_68166035 0.16 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 186
 0.66
chr10_94179898_94180049 0.16 ENSG00000207895
 .
 21088
 0.21
chr15_90319837_90320135 0.16 MESP2
 mesoderm posterior 2 homolog (mouse)
 397
 0.79
chr3_55522536_55522942 0.16 WNT5A-AS1
 WNT5A antisense RNA 1
 1012
 0.47
chr2_62592200_62592351 0.16 ENSG00000238809
 .
 100145
 0.07
chr2_231742152_231742309 0.16 AC012507.3
8985
 0.17
chr22_20287333_20287484 0.16 XXbac-B444P24.13
18864
 0.11
chr2_109745417_109745568 0.16 SH3RF3
 SH3 domain containing ring finger 3
 312
 0.92
chr5_59189611_59189822 0.16 PDE4D
 phosphodiesterase 4D, cAMP-specific
 91
 0.98
chr16_2630606_2630757 0.16 RP11-20I23.7
8327
 0.07
chr10_100227678_100227852 0.16 HPS1
 Hermansky-Pudlak syndrome 1
 21082
 0.19
chr12_53465850_53466141 0.16 SPRYD3
 SPRY domain containing 3
 7166
 0.11
chr11_108368869_108369152 0.16 KDELC2
 KDEL (Lys-Asp-Glu-Leu) containing 2
 149
 0.96
chr6_72129499_72129753 0.16 ENSG00000207827
 .
 16302
 0.22
chr10_3306842_3307061 0.16 PITRM1
 pitrilysin metallopeptidase 1
 91948
 0.09
chr8_27695395_27695562 0.16 PBK
 PDZ binding kinase
 121
 0.96
chr21_45585843_45585994 0.16 AP001055.1
7662
 0.15
chr15_66914114_66914568 0.16 RP11-321F6.1
 HCG2003567; Uncharacterized protein
 39813
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.3 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.2 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0046084 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0031650 regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.0 GO:0044256 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.1 GO:1902913 positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:0051797 regulation of hair follicle development(GO:0051797)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0045073 regulation of chemokine biosynthetic process(GO:0045073)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0010224 response to UV-B(GO:0010224)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.0 GO:0044557 relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.0 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0032190 acrosin binding(GO:0032190)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.2 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0032142 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099) L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0016248 channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.0 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets