CREMA results: HINFP

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Transcription factors associated with HINFP

Gene Symbol	Gene ID	Gene Info
HINFP Ensembl NCBI GeneCards UniProt	ENSG00000172273.8	histone H4 transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

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CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_118991739_118991981	HINFP	437	0.633581	0.79	1.0e-02	Click!
chr11_118992520_118992671	HINFP	269	0.791859	0.70	3.4e-02	Click!
chr11_118992825_118993315	HINFP	744	0.409595	0.76	1.8e-02	Click!
chr11_118997443_118997594	HINFP	2820	0.111246	0.58	1.0e-01	Click!
chr11_118997626_118997777	HINFP	3003	0.107055	0.56	1.1e-01	Click!

Showing 1 to 5 of 5 entries

Activity of the HINFP motif across conditions

Conditions sorted by the z-value of the HINFP motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

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Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_46067194_46067379	1.71	CTIF	CBP80/20-dependent translation initiation factor	820	0.71
chr12_96252505_96252656	1.36	RP11-536G4.2		4	0.62
chr14_76044324_76044726	1.27	FLVCR2	feline leukemia virus subgroup C cellular receptor family, member 2	435	0.75
chr8_6263739_6263890	1.21	RP11-115C21.2		249	0.56
chr17_77775042_77775193	1.16	CBX8	chromobox homolog 8	215	0.81
chr2_27530380_27530531	1.15	UCN	urocortin	858	0.38
chr12_49373722_49373887	1.01	WNT1	wingless-type MMTV integration site family, member 1	1406	0.17
chrX_134232424_134232575	0.99	FAM127B	family with sequence similarity 127, member B	46294	0.12
chr1_117602981_117603207	0.99	TTF2	transcription termination factor, RNA polymerase II	169	0.9
chr19_6372839_6372990	0.98	ALKBH7	alkB, alkylation repair homolog 7 (E. coli)	470	0.62

Showing 1 to 10 of 200 entries

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0	1.7	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.1	1.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5	1.4	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	1.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.4	1.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	1.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	1.0	GO:0016574	histone ubiquitination(GO:0016574)
0.3	0.9	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2	0.9	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)

Showing 1 to 10 of 339 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.9	GO:0043025	neuronal cell body(GO:0043025)
0.0	1.4	GO:0016592	mediator complex(GO:0016592)
0.0	1.4	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	1.3	GO:0031519	PcG protein complex(GO:0031519)
0.4	1.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.9	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Showing 1 to 10 of 106 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	GO:0070064	proline-rich region binding(GO:0070064)
0.1	2.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	1.7	GO:0035064	methylated histone binding(GO:0035064)
0.1	1.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.4	1.2	GO:0016362	activin receptor activity, type II(GO:0016362)
0.1	1.0	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.0	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.1	0.9	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.9	GO:0017048	Rho GTPase binding(GO:0017048)

Showing 1 to 10 of 212 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.1	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.3	PID E2F PATHWAY	E2F transcription factor network
0.0	1.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.1	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.8	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.8	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling

Showing 1 to 10 of 46 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	1.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.9	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Showing 1 to 10 of 88 entries

Results for HINFP

Z-value: 3.01

Motif logo

Transcription factors associated with HINFP

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HINFP motif across conditions

Conditions sorted by the z-value of the HINFP motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: