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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HINFP1

Z-value: 0.23

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity of the HINFP1 motif across conditions

Conditions sorted by the z-value of the HINFP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_19174243_19174394 0.13 SLC25A42
solute carrier family 25, member 42
490
0.72
chr8_41511463_41511684 0.09 NKX6-3
NK6 homeobox 3
2718
0.18
chr19_4304476_4304627 0.08 FSD1
fibronectin type III and SPRY domain containing 1
46
0.94
chr7_15726263_15726517 0.08 MEOX2
mesenchyme homeobox 2
47
0.98
chr14_73704548_73704719 0.08 PAPLN
papilin, proteoglycan-like sulfated glycoprotein
428
0.79
chrX_40034598_40034749 0.08 BCOR
BCL6 corepressor
1900
0.49
chr3_12910192_12910522 0.08 AC034198.7

18199
0.14
chr19_33765417_33765674 0.08 CTD-2540B15.11

25295
0.11
chr4_154144370_154144521 0.07 TRIM2
tripartite motif containing 2
18827
0.19
chr15_68112430_68112716 0.07 SKOR1
SKI family transcriptional corepressor 1
531
0.83
chr6_167370368_167370519 0.06 RNASET2
ribonuclease T2
186
0.87
chr7_101460826_101460977 0.06 CUX1
cut-like homeobox 1
19
0.98
chr6_163834522_163834673 0.06 QKI
QKI, KH domain containing, RNA binding
1078
0.69
chr16_718371_718640 0.05 RHOT2
ras homolog family member T2
296
0.66
chr2_71693709_71693860 0.05 DYSF
dysferlin
48
0.98
chr1_29448600_29448837 0.05 TMEM200B
transmembrane protein 200B
295
0.91
chr10_49731313_49731514 0.05 ARHGAP22
Rho GTPase activating protein 22
868
0.65
chr19_10654183_10654334 0.05 ATG4D
autophagy related 4D, cysteine peptidase
336
0.76
chr2_30454407_30454726 0.05 LBH
limb bud and heart development
163
0.96
chr7_155166439_155166623 0.05 BLACE
B-cell acute lymphoblastic leukemia expressed
5902
0.18
chr2_11052081_11052232 0.05 KCNF1
potassium voltage-gated channel, subfamily F, member 1
93
0.98
chr16_86968692_86968843 0.05 RP11-899L11.3

280754
0.01
chr19_48996822_48997092 0.04 LMTK3
lemur tyrosine kinase 3
18104
0.09
chr16_75033732_75033945 0.04 ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
595
0.76
chr11_76381975_76382126 0.04 LRRC32
leucine rich repeat containing 32
259
0.91
chr13_25745444_25745788 0.04 AMER2
APC membrane recruitment protein 2
241
0.93
chr1_110753630_110753781 0.04 KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
390
0.72
chr1_228194389_228194540 0.04 WNT3A
wingless-type MMTV integration site family, member 3A
288
0.9
chr1_62784603_62784939 0.04 KANK4
KN motif and ankyrin repeat domains 4
201
0.95
chr8_55379558_55379709 0.03 SOX17
SRY (sex determining region Y)-box 17
9138
0.26
chr6_100061828_100062580 0.03 PRDM13
PR domain containing 13
7598
0.19
chr9_130965791_130965942 0.03 DNM1
dynamin 1
141
0.86
chr1_9600228_9600966 0.03 SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
1056
0.57
chr2_173292406_173292557 0.03 ITGA6
integrin, alpha 6
36
0.95
chr10_112403450_112403743 0.03 RBM20
RNA binding motif protein 20
559
0.6
chr10_119135437_119135737 0.03 PDZD8
PDZ domain containing 8
609
0.77
chr15_99646176_99646459 0.03 RP11-654A16.3

287
0.81
chr15_31619464_31619615 0.03 KLF13
Kruppel-like factor 13
481
0.89
chr2_178128811_178128962 0.03 AC079305.10

201
0.65
chr19_41111618_41111808 0.03 ENSG00000266164
.
1242
0.36
chr4_183369356_183369507 0.02 TENM3
teneurin transmembrane protein 3
721
0.79
chr18_11981846_11982049 0.02 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
278
0.9
chr3_196696276_196696552 0.02 PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
672
0.62
chr21_36261605_36261866 0.02 RUNX1
runt-related transcription factor 1
299
0.95
chr2_23886218_23886369 0.02 KLHL29
kelch-like family member 29
21031
0.26
chr1_11724600_11724751 0.02 FBXO6
F-box protein 6
494
0.7
chr1_207226735_207226886 0.02 PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
154
0.8
chr1_207082970_207083121 0.02 IL24
interleukin 24
11867
0.14
chr20_1875010_1875174 0.02 SIRPA
signal-regulatory protein alpha
62
0.98
chr6_157801331_157801482 0.02 ZDHHC14
zinc finger, DHHC-type containing 14
759
0.74
chr1_10458488_10458749 0.02 PGD
phosphogluconate dehydrogenase
31
0.96
chr5_92956044_92956482 0.02 ENSG00000251725
.
231
0.94
chr8_146023905_146024105 0.02 ZNF517
zinc finger protein 517
256
0.85
chr1_936066_936217 0.02 HES4
hes family bHLH transcription factor 4
589
0.53
chr17_56234380_56234651 0.01 OR4D1
olfactory receptor, family 4, subfamily D, member 1
2021
0.25
chr1_231297605_231297900 0.01 TRIM67
tripartite motif containing 67
106
0.97
chr7_157486328_157486479 0.01 AC006003.3

46745
0.16
chr2_130939540_130939691 0.01 MZT2B
mitotic spindle organizing protein 2B
114
0.8
chr8_10191959_10192233 0.01 MSRA
methionine sulfoxide reductase A
33051
0.2
chr17_12921001_12921175 0.01 ELAC2
elaC ribonuclease Z 2
88
0.97
chr5_179223700_179223978 0.01 ENSG00000221394
.
1507
0.23
chr5_129239898_129240062 0.01 CHSY3
chondroitin sulfate synthase 3
185
0.93
chr14_36002497_36002787 0.01 INSM2
insulinoma-associated 2
606
0.82
chr16_1030754_1030971 0.01 AC009041.2

390
0.44
chr6_159360341_159360710 0.01 ENSG00000223191
.
12922
0.19
chr16_4165609_4165795 0.01 ADCY9
adenylate cyclase 9
484
0.85
chr19_50432907_50433192 0.01 NUP62
nucleoporin 62kDa
48
0.67
chr3_139654158_139654536 0.01 CLSTN2
calsyntenin 2
320
0.94
chr2_238582144_238582414 0.01 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
18509
0.2
chr21_32930676_32931085 0.01 TIAM1
T-cell lymphoma invasion and metastasis 1
410
0.65
chrX_71131064_71131256 0.01 NHSL2
NHS-like 2
222
0.95
chr17_17603799_17604090 0.01 RAI1
retinoic acid induced 1
18135
0.17
chr16_30217757_30217917 0.01 RP11-347C12.3
Uncharacterized protein
354
0.72
chr13_28528810_28529001 0.01 ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
9562
0.14
chrY_21154851_21155002 0.01 ENSG00000252766
.
26047
0.25
chr8_145550773_145550924 0.01 DGAT1
diacylglycerol O-acyltransferase 1
275
0.78
chr6_18277677_18277884 0.01 ENSG00000199715
.
4283
0.21
chr2_129079674_129079825 0.01 HS6ST1
heparan sulfate 6-O-sulfotransferase 1
3598
0.29
chr19_33773041_33773249 0.01 CTD-2540B15.11

17695
0.12
chr17_15847824_15848196 0.01 ADORA2B
adenosine A2b receptor
221
0.94
chr4_87812904_87813288 0.01 C4orf36
chromosome 4 open reading frame 36
452
0.86
chrX_70150765_70150916 0.01 SLC7A3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
106
0.97
chr1_155051511_155051662 0.01 EFNA3
ephrin-A3
201
0.85
chr1_93426537_93426688 0.01 FAM69A
family with sequence similarity 69, member A
445
0.74
chr7_132260829_132261020 0.01 PLXNA4
plexin A4
305
0.94
chr6_3850608_3850759 0.01 FAM50B
family with sequence similarity 50, member B
1061
0.56
chr9_131419199_131419842 0.01 WDR34
WD repeat domain 34
454
0.72
chr10_50606234_50606396 0.01 DRGX
dorsal root ganglia homeobox
2818
0.27
chr17_54910262_54910635 0.01 C17orf67
chromosome 17 open reading frame 67
808
0.44
chr11_6676804_6676955 0.01 DCHS1
dachsous cadherin-related 1
206
0.87
chr12_125053352_125053581 0.01 NCOR2
nuclear receptor corepressor 2
1456
0.58
chr7_22539874_22540117 0.01 STEAP1B
STEAP family member 1B
122
0.97
chr15_65670506_65670816 0.01 IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
283
0.9
chr11_120894551_120894800 0.00 TBCEL
tubulin folding cofactor E-like
106
0.98
chr11_63771531_63771682 0.00 OTUB1
OTU domain, ubiquitin aldehyde binding 1
17292
0.1
chr17_16487655_16488110 0.00 ZNF287
zinc finger protein 287
15362
0.16
chr5_159546835_159547068 0.00 PWWP2A
PWWP domain containing 2A
521
0.78
chr22_50969265_50969416 0.00 TYMP
thymidine phosphorylase
855
0.28
chr1_117113459_117113610 0.00 CD58
CD58 molecule
114
0.96
chr6_45631315_45631560 0.00 ENSG00000252738
.
17596
0.29
chrX_49033431_49033582 0.00 PLP2
proteolipid protein 2 (colonic epithelium-enriched)
5233
0.09
chr9_139501841_139501992 0.00 ENSG00000252440
.
4949
0.12
chr19_8477814_8477965 0.00 MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
265
0.84
chr2_202316811_202317113 0.00 STRADB
STE20-related kinase adaptor beta
443
0.6
chr7_44835539_44835875 0.00 PPIA
peptidylprolyl isomerase A (cyclophilin A)
572
0.69
chr19_12780803_12780979 0.00 WDR83
WD repeat domain 83
171
0.72
chr1_210111505_210111656 0.00 SYT14
synaptotagmin XIV
4
0.99
chr1_1285139_1285398 0.00 DVL1
dishevelled segment polarity protein 1
538
0.51
chr7_89783512_89783724 0.00 STEAP1
six transmembrane epithelial antigen of the prostate 1
71
0.97

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0048669 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) collateral sprouting in absence of injury(GO:0048669) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)