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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HLF_TEF

Z-value: 1.57

Motif logo

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Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
HLF
ENSG00000108924.9 HLF transcription factor, PAR bZIP family member
TEF
ENSG00000167074.10 TEF transcription factor, PAR bZIP family member

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_53340851_53341002HLF14470.489344-0.665.1e-02Click!
chr17_53346103_53346254HLF10010.6100990.655.9e-02Click!
chr17_53341084_53341235HLF12140.550873-0.646.2e-02Click!
chr17_53245033_53245184HLF972650.0784700.636.9e-02Click!
chr17_53315545_53315826HLF266880.2126190.491.8e-01Click!
chr22_41763864_41764015TEF6020.6728970.675.1e-02Click!
chr22_41763473_41763758TEF2780.8819600.618.0e-02Click!
chr22_41776460_41776636TEF13850.3390770.551.2e-01Click!
chr22_41762881_41763188TEF3030.8674580.541.4e-01Click!
chr22_41809018_41809169TEF301540.1082850.531.4e-01Click!

Activity of the HLF_TEF motif across conditions

Conditions sorted by the z-value of the HLF_TEF motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_71006405_71006665 0.94 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 10921
 0.26
chr3_65930585_65930845 0.88 ENSG00000264716
 .
 3793
 0.23
chr12_48163883_48164256 0.75 RAPGEF3
 Rap guanine nucleotide exchange factor (GEF) 3
 748
 0.49
chr11_112027840_112028079 0.73 IL18
 interleukin 18 (interferon-gamma-inducing factor)
 6838
 0.11
chr21_40386888_40387293 0.73 ENSG00000272015
 .
 120381
 0.05
chr8_61896258_61896409 0.72 CLVS1
 clavesin 1
 73384
 0.12
chr6_132513964_132514185 0.70 ENSG00000265669
 .
 77671
 0.11
chr10_22723256_22723780 0.67 RP11-301N24.3
73417
 0.1
chr6_5206187_5206422 0.67 ENSG00000264541
 .
 18726
 0.19
chr10_64380892_64381169 0.66 ZNF365
 zinc finger protein 365
 22503
 0.22
chr20_20840342_20840493 0.65 ENSG00000264361
 .
 121043
 0.06
chr4_38822000_38822151 0.63 TLR6
 toll-like receptor 6
 9085
 0.16
chr4_48226743_48226894 0.60 TEC
 tec protein tyrosine kinase
 45063
 0.14
chr10_22284671_22284822 0.60 DNAJC1
 DnaJ (Hsp40) homolog, subfamily C, member 1
 7582
 0.28
chr12_48340702_48340853 0.60 VDR
 vitamin D (1,25- dihydroxyvitamin D3) receptor
 3946
 0.19
chr4_77303492_77303643 0.60 ENSG00000199857
 .
 19662
 0.14
chr5_145375816_145375967 0.60 SH3RF2
 SH3 domain containing ring finger 2
 58451
 0.13
chr6_14766197_14766507 0.58 ENSG00000206960
 .
 119586
 0.07
chr13_40025518_40025722 0.58 ENSG00000238408
 .
 4267
 0.34
chr3_64034181_64034364 0.58 RP11-129B22.1
19368
 0.1
chr12_8043408_8043946 0.57 SLC2A14
 solute carrier family 2 (facilitated glucose transporter), member 14
 67
 0.95
chr8_741942_742093 0.57 ERICH1-AS1
 ERICH1 antisense RNA 1
 54275
 0.14
chr4_140967735_140967886 0.57 RP11-392B6.1
81359
 0.1
chr12_65599568_65599732 0.56 LEMD3
 LEM domain containing 3
 36299
 0.17
chr21_43352747_43353275 0.56 C2CD2
 C2 calcium-dependent domain containing 2
 6212
 0.19
chr6_18427728_18428016 0.54 ENSG00000238458
 .
 25589
 0.2
chr12_102250942_102251233 0.53 ENSG00000252863
 .
 14492
 0.12
chr7_133224861_133225123 0.53 EXOC4
 exocyst complex component 4
 36224
 0.24
chr1_214598693_214598940 0.53 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 39330
 0.19
chr2_219020666_219020817 0.52 CXCR1
 chemokine (C-X-C motif) receptor 1
 10977
 0.14
chr6_41680623_41680774 0.52 TFEB
 transcription factor EB
 7020
 0.13
chr3_124500151_124500305 0.51 ITGB5-AS1
 ITGB5 antisense RNA 1
 226
 0.93
chr3_185466059_185466210 0.51 ENSG00000265470
 .
 19558
 0.2
chr6_11536168_11536406 0.51 TMEM170B
 transmembrane protein 170B
 1651
 0.46
chr13_51939096_51939247 0.50 RP11-24B19.3
1592
 0.28
chr5_148365723_148365874 0.50 RP11-44B19.1
15895
 0.18
chr10_101288694_101289161 0.50 RP11-129J12.2
1727
 0.34
chr14_97292729_97292880 0.49 VRK1
 vaccinia related kinase 1
 26421
 0.26
chr6_135061273_135061513 0.49 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
 188906
 0.03
chr19_6103075_6103226 0.49 CTB-66B24.1
6183
 0.15
chr8_104293348_104293656 0.49 RP11-318M2.2
4628
 0.2
chr1_246271383_246271534 0.49 RP11-36N20.1
470
 0.86
chr9_70615947_70616098 0.49 AL591479.1
 Uncharacterized protein
 30567
 0.22
chr9_42221074_42221225 0.48 RP11-216M21.7
145943
 0.04
chr4_15081864_15082159 0.48 ENSG00000199420
 .
 13707
 0.24
chr5_14544889_14545095 0.48 FAM105A
 family with sequence similarity 105, member A
 36892
 0.19
chr20_10286775_10287859 0.48 ENSG00000211588
 .
 55561
 0.13
chr6_34255201_34255352 0.48 C6orf1
 chromosome 6 open reading frame 1
 38029
 0.15
chr7_92456741_92457310 0.46 CDK6
 cyclin-dependent kinase 6
 6206
 0.23
chr21_45005885_45006040 0.46 HSF2BP
 heat shock transcription factor 2 binding protein
 72063
 0.1
chr18_24326449_24326698 0.45 ENSG00000265369
 .
 57080
 0.13
chr2_216838775_216839059 0.45 MREG
 melanoregulin
 39429
 0.18
chr12_89700664_89700866 0.45 ENSG00000238302
 .
 24703
 0.22
chr16_69775420_69775717 0.45 NOB1
 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
 13275
 0.1
chr2_26622798_26622949 0.45 DRC1
 dynein regulatory complex subunit 1 homolog (Chlamydomonas)
 1911
 0.36
chr9_45472222_45472373 0.45 AL354718.1
 Uncharacterized protein
 30755
 0.25
chr16_81642292_81642617 0.45 CMIP
 c-Maf inducing protein
 36509
 0.21
chr2_169542981_169543171 0.44 ENSG00000199348
 .
 80070
 0.09
chr19_42947007_42947215 0.43 CXCL17
 chemokine (C-X-C motif) ligand 17
 89
 0.95
chr18_54524017_54524317 0.43 RP11-383D22.1
17034
 0.22
chr9_80359497_80359648 0.43 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 78343
 0.1
chr3_106466004_106466155 0.43 ENSG00000200361
 .
 58554
 0.17
chr12_121158667_121159015 0.43 ENSG00000265455
 .
 2155
 0.16
chr2_145130083_145130281 0.43 GTDC1
 glycosyltransferase-like domain containing 1
 40099
 0.19
chr11_110349991_110350329 0.43 FDX1
 ferredoxin 1
 49553
 0.18
chr14_75122953_75123104 0.43 AREL1
 apoptosis resistant E3 ubiquitin protein ligase 1
 19890
 0.15
chr1_61719110_61719389 0.42 NFIA
 nuclear factor I/A
 98873
 0.08
chr2_210337378_210337560 0.42 MAP2
 microtubule-associated protein 2
 48687
 0.19
chr7_41516088_41516239 0.42 INHBA-AS1
 INHBA antisense RNA 1
 217351
 0.02
chr12_116436351_116436502 0.42 MED13L
 mediator complex subunit 13-like
 15186
 0.22
chr14_91163076_91163339 0.42 RP11-661G16.2
470
 0.81
chr9_3299512_3299760 0.42 RFX3
 regulatory factor X, 3 (influences HLA class II expression)
 28898
 0.26
chr12_71842305_71842456 0.42 TSPAN8
 tetraspanin 8
 6702
 0.24
chr5_88120771_88120961 0.42 MEF2C
 myocyte enhancer factor 2C
 709
 0.77
chr7_149450583_149450734 0.41 ZNF467
 zinc finger protein 467
 19650
 0.19
chr6_116690381_116690532 0.41 DSE
 dermatan sulfate epimerase
 554
 0.78
chr7_92437724_92438202 0.41 CDK6
 cyclin-dependent kinase 6
 25268
 0.19
chr20_49026246_49026397 0.41 ENSG00000244376
 .
 19699
 0.22
chr11_12088585_12089097 0.41 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 26702
 0.22
chr6_37008004_37008155 0.41 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 4528
 0.22
chr2_172380569_172381265 0.41 CYBRD1
 cytochrome b reductase 1
 1328
 0.53
chr2_178283039_178283431 0.41 AGPS
 alkylglycerone phosphate synthase
 25739
 0.14
chr3_141248480_141249204 0.41 RASA2-IT1
 RASA2 intronic transcript 1 (non-protein coding)
 4867
 0.27
chr16_71760597_71760829 0.40 PHLPP2
 PH domain and leucine rich repeat protein phosphatase 2
 2109
 0.19
chr4_118955423_118955622 0.40 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
 22
 0.99
chr17_19172351_19172531 0.40 EPN2
 epsin 2
 11208
 0.12
chr10_21311864_21312015 0.40 NEBL
 nebulette
 47007
 0.18
chr6_15463967_15464118 0.40 JARID2
 jumonji, AT rich interactive domain 2
 62953
 0.13
chr15_67094989_67095410 0.39 SMAD6
 SMAD family member 6
 91164
 0.08
chr1_241705552_241705751 0.39 KMO
 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
 9946
 0.22
chr5_148181532_148181683 0.39 ADRB2
 adrenoceptor beta 2, surface
 24549
 0.23
chr3_87849755_87849906 0.39 ENSG00000200703
 .
 58031
 0.15
chr1_207203760_207203911 0.39 C1orf116
 chromosome 1 open reading frame 116
 2257
 0.21
chr1_85154249_85154907 0.39 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
 1394
 0.5
chr5_90677472_90677623 0.39 ARRDC3
 arrestin domain containing 3
 1629
 0.47
chr17_47393434_47393962 0.38 ENSG00000251964
 .
 9565
 0.15
chr5_134702384_134702535 0.38 C5orf66
 chromosome 5 open reading frame 66
 28830
 0.14
chr7_131156247_131156398 0.38 RP11-180C16.1
26131
 0.24
chr19_32837185_32838232 0.38 ZNF507
 zinc finger protein 507
 1083
 0.51
chr14_97886866_97887017 0.38 ENSG00000240730
 .
 109569
 0.08
chr12_94997883_94998034 0.38 TMCC3
 transmembrane and coiled-coil domain family 3
 11879
 0.23
chr3_128964455_128964687 0.38 COPG1
 coatomer protein complex, subunit gamma 1
 3878
 0.19
chrX_92616111_92616262 0.38 NAP1L3
 nucleosome assembly protein 1-like 3
 312381
 0.01
chrX_15874840_15875069 0.38 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
 1900
 0.39
chr12_106673629_106673780 0.37 ENSG00000238609
 .
 3063
 0.23
chr12_70079938_70080089 0.37 BEST3
 bestrophin 3
 3043
 0.26
chr12_66289441_66289878 0.37 RP11-366L20.2
 Uncharacterized protein
 13712
 0.17
chr7_141611302_141611453 0.37 OR9N1P
 olfactory receptor, family 9, subfamily N, member 1 pseudogene
 114
 0.94
chr4_46007135_46007286 0.37 ENSG00000222257
 .
 10074
 0.31
chr8_107978697_107978848 0.37 ABRA
 actin-binding Rho activating protein
 196299
 0.03
chr19_46586098_46586249 0.37 IGFL4
 IGF-like family member 4
 5821
 0.17
chr14_73643539_73643710 0.37 PSEN1
 presenilin 1
 9087
 0.19
chr2_122405151_122406002 0.37 CLASP1
 cytoplasmic linker associated protein 1
 1476
 0.32
chr9_127420744_127420996 0.36 MIR181A2HG
 MIR181A2 host gene (non-protein coding)
 124
 0.96
chr8_128003052_128003209 0.36 ENSG00000212451
 .
 319363
 0.01
chr3_153850737_153851019 0.36 ARHGEF26
 Rho guanine nucleotide exchange factor (GEF) 26
 11649
 0.22
chr11_95786586_95786916 0.36 MTMR2
 myotubularin related protein 2
 129292
 0.05
chr7_38969302_38969595 0.36 VPS41
 vacuolar protein sorting 41 homolog (S. cerevisiae)
 288
 0.94
chr11_92931221_92931372 0.36 SLC36A4
 solute carrier family 36 (proton/amino acid symporter), member 4
 167
 0.97
chr8_130594633_130594805 0.36 ENSG00000266387
 .
 84806
 0.07
chr14_75323168_75323351 0.36 PROX2
 prospero homeobox 2
 7278
 0.14
chr4_91278223_91278374 0.36 ENSG00000252087
 .
 12976
 0.31
chr11_75367473_75367624 0.36 MAP6
 microtubule-associated protein 6
 11931
 0.14
chr13_88727217_88727368 0.36 ENSG00000223059
 .
 112883
 0.08
chr1_21277303_21277509 0.36 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 9295
 0.23
chr8_67042092_67042243 0.36 TRIM55
 tripartite motif containing 55
 2889
 0.34
chr3_37860112_37860344 0.36 ENSG00000235257
 .
 2673
 0.3
chr13_72142845_72142996 0.36 DACH1
 dachshund homolog 1 (Drosophila)
 297987
 0.01
chr2_160374836_160375140 0.36 ENSG00000207117
 .
 17869
 0.24
chr4_68312692_68312843 0.35 ENSG00000206629
 .
 17295
 0.26
chr15_52436562_52436713 0.35 CTD-2184D3.7
6012
 0.16
chr6_27570448_27570599 0.35 ENSG00000206671
 .
 6332
 0.22
chr12_1427689_1428011 0.35 RP5-951N9.2
67149
 0.11
chr2_232106617_232106773 0.35 ARMC9
 armadillo repeat containing 9
 6630
 0.24
chr13_91067405_91067695 0.35 ENSG00000207858
 .
 184114
 0.03
chr5_175893259_175893617 0.35 ENSG00000221373
 .
 14675
 0.12
chr1_90408609_90408825 0.35 ENSG00000252797
 .
 44786
 0.15
chr17_29553936_29554129 0.35 NF1
 neurofibromin 1
 26478
 0.15
chr6_149727250_149727401 0.35 SUMO4
 small ubiquitin-like modifier 4
 5830
 0.2
chr11_114034929_114035103 0.35 ENSG00000221112
 .
 77365
 0.09
chr9_22165561_22165745 0.34 CDKN2B-AS1
 CDKN2B antisense RNA 1
 51976
 0.16
chr1_27425346_27425645 0.34 SLC9A1
 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
 55478
 0.1
chr8_99248451_99248632 0.34 ENSG00000252558
 .
 44000
 0.14
chr11_116747490_116747649 0.34 SIK3-IT1
 SIK3 intronic transcript 1 (non-protein coding)
 13868
 0.12
chr11_35954304_35954455 0.34 LDLRAD3
 low density lipoprotein receptor class A domain containing 3
 11152
 0.18
chr16_48364740_48364935 0.34 LONP2
 lon peptidase 2, peroxisomal
 3386
 0.26
chr5_36948326_36948572 0.34 NIPBL
 Nipped-B homolog (Drosophila)
 71557
 0.13
chr5_143241658_143241809 0.34 HMHB1
 histocompatibility (minor) HB-1
 50007
 0.18
chr9_35526012_35526444 0.33 RUSC2
 RUN and SH3 domain containing 2
 12401
 0.15
chr17_15869540_15869896 0.33 ADORA2B
 adenosine A2b receptor
 21487
 0.15
chr2_175018489_175018640 0.33 OLA1
 Obg-like ATPase 1
 64110
 0.12
chr11_19265860_19266011 0.33 E2F8
 E2F transcription factor 8
 2768
 0.28
chr2_174026267_174026418 0.33 MLK7-AS1
 MLK7 antisense RNA 1
 45998
 0.16
chr5_115374031_115374427 0.33 ENSG00000220996
 .
 4729
 0.15
chr3_51654767_51654946 0.33 RAD54L2
 RAD54-like 2 (S. cerevisiae)
 8551
 0.17
chr5_160121113_160121264 0.33 CTC-529G1.1
8830
 0.21
chr1_183430720_183430871 0.33 SMG7
 SMG7 nonsense mediated mRNA decay factor
 10711
 0.21
chr1_212433899_212434288 0.33 PPP2R5A
 protein phosphatase 2, regulatory subunit B', alpha
 24786
 0.16
chr21_23887924_23888075 0.33 ENSG00000263796
 .
 164993
 0.04
chr6_106994075_106994866 0.33 AIM1
 absent in melanoma 1
 5441
 0.23
chr10_77190817_77191121 0.33 RP11-399K21.10
377
 0.87
chr7_105807957_105808108 0.33 ENSG00000201796
 .
 40581
 0.17
chr11_103935040_103935191 0.32 PDGFD
 platelet derived growth factor D
 27361
 0.2
chr2_54191777_54192195 0.32 ACYP2
 acylphosphatase 2, muscle type
 5989
 0.21
chr9_74363230_74363515 0.32 TMEM2
 transmembrane protein 2
 19930
 0.27
chr8_59084985_59085323 0.32 FAM110B
 family with sequence similarity 110, member B
 178041
 0.03
chr2_101728983_101729400 0.32 ENSG00000265860
 .
 19160
 0.19
chr5_139532409_139532571 0.32 CYSTM1
 cysteine-rich transmembrane module containing 1
 21737
 0.12
chr8_131278471_131278622 0.32 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 19258
 0.26
chr1_25458423_25458574 0.32 RP4-706G24.1
76132
 0.08
chr3_18787817_18787968 0.32 ENSG00000228956
 .
 656
 0.84
chr11_78101755_78101906 0.32 RP11-452H21.2
2723
 0.27
chr17_58516951_58517102 0.32 C17orf64
 chromosome 17 open reading frame 64
 17156
 0.18
chr2_135843202_135843353 0.32 ENSG00000238337
 .
 19973
 0.17
chr5_151063563_151063813 0.32 SPARC
 secreted protein, acidic, cysteine-rich (osteonectin)
 1103
 0.43
chr9_31590126_31590277 0.32 ENSG00000252313
 .
 703355
 0.0
chr18_29260479_29260630 0.32 B4GALT6
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
 3913
 0.17
chr7_102452212_102452699 0.31 ENSG00000252643
 .
 22597
 0.16
chr11_8719978_8720129 0.31 ST5
 suppression of tumorigenicity 5
 3851
 0.13
chr9_297842_297993 0.31 DOCK8
 dedicator of cytokinesis 8
 24847
 0.18
chrX_135967912_135968067 0.31 RBMX
 RNA binding motif protein, X-linked
 5066
 0.21
chr20_47448722_47448873 0.31 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 4377
 0.31
chr1_174758122_174758399 0.31 RABGAP1L
 RAB GTPase activating protein 1-like
 10810
 0.28
chr5_148645320_148645471 0.31 AFAP1L1
 actin filament associated protein 1-like 1
 6039
 0.14
chr1_234639139_234639392 0.31 TARBP1
 TAR (HIV-1) RNA binding protein 1
 24416
 0.19
chr1_9962207_9962358 0.31 CTNNBIP1
 catenin, beta interacting protein 1
 8039
 0.14
chr12_89777034_89777222 0.31 DUSP6
 dual specificity phosphatase 6
 30080
 0.2
chr10_73104848_73104999 0.31 ENSG00000238918
 .
 19838
 0.18
chr8_96875884_96876062 0.31 ENSG00000223297
 .
 184830
 0.03
chr4_38077270_38077549 0.31 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 29917
 0.24
chr3_171528829_171529427 0.31 PLD1
 phospholipase D1, phosphatidylcholine-specific
 844
 0.52
chr12_77777777_77777928 0.31 AC073528.1
172716
 0.04
chr1_234755566_234755985 0.31 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 10504
 0.19
chr20_5837496_5837647 0.30 ENSG00000202380
 .
 33130
 0.16
chr2_208734859_208735279 0.30 AC083900.1
430
 0.86
chr2_160470412_160470682 0.30 AC009506.1
1260
 0.4
chr5_127059262_127059522 0.30 CTC-548H10.2
59671
 0.14
chr12_113251939_113252090 0.30 RPH3A
 rabphilin 3A homolog (mouse)
 14110
 0.24
chr2_192241823_192241993 0.30 ENSG00000252130
 .
 6244
 0.26
chr12_6292503_6292996 0.30 CD9
 CD9 molecule
 16132
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.3 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.1 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.4 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.2 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1 0.2 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1 0.2 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.4 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0070339 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0044557 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.0 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.2 GO:0046464 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0042095 interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0052555 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.0 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)