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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HMGA2

Z-value: 1.67

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Transcription factors associated with HMGA2

Gene Symbol	Gene ID	Gene Info
HMGA2 Ensembl NCBI GeneCards UniProt	ENSG00000149948.9	high mobility group AT-hook 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_65995970_65996121	HMGA2	221866	0.020516	-0.93	2.7e-04	Click!
chr12_65998055_65998206	HMGA2	219781	0.020872	-0.87	2.3e-03	Click!
chr12_66029471_66029622	HMGA2	188365	0.027592	-0.85	3.6e-03	Click!
chr12_66043673_66043824	HMGA2	174163	0.031583	-0.84	4.3e-03	Click!
chr12_66226396_66226547	HMGA2	7568	0.211058	-0.83	5.3e-03	Click!

Activity of the HMGA2 motif across conditions

Conditions sorted by the z-value of the HMGA2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_9716017_9716306	0.72	C1orf200	chromosome 1 open reading frame 200	1517	0.35
chr4_90225162_90225490	0.70	GPRIN3	GPRIN family member 3	3835	0.36
chr2_68995416_68995584	0.68	ARHGAP25	Rho GTPase activating protein 25	6433	0.26
chr4_90218630_90219104	0.58	GPRIN3	GPRIN family member 3	10294	0.3
chr8_82008078_82008354	0.57	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	16087	0.28
chr5_133560624_133561078	0.56	PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	394	0.54
chr1_167469197_167469632	0.56	CD247	CD247 molecule	18361	0.19
chr1_66818461_66818612	0.54	PDE4B	phosphodiesterase 4B, cAMP-specific	1529	0.56
chr4_109073543_109073694	0.54	LEF1	lymphoid enhancer-binding factor 1	13839	0.22
chr13_99830656_99830890	0.53	UBAC2	UBA domain containing 2	22255	0.17
chrX_19764292_19764574	0.53	SH3KBP1	SH3-domain kinase binding protein 1	96	0.98
chr11_121329085_121329622	0.53	RP11-730K11.1		5631	0.26
chr1_198657444_198657765	0.51	RP11-553K8.5		21414	0.23
chr13_24836062_24836323	0.50	SPATA13-AS1	SPATA13 antisense RNA 1	7615	0.17
chr1_155916745_155916975	0.48	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	4679	0.1
chr14_99449668_99449965	0.48	AL162151.4		174937	0.03
chr4_153563986_153564137	0.48	RP11-768B22.2		23459	0.19
chr14_90185934_90186201	0.47	ENSG00000200312	.	7212	0.23
chr1_198617249_198617743	0.47	PTPRC	protein tyrosine phosphatase, receptor type, C	9204	0.24
chr15_93431988_93432150	0.47	CHD2	chromodomain helicase DNA binding protein 2	5543	0.2
chr2_158271446_158271770	0.46	CYTIP	cytohesin 1 interacting protein	24318	0.19
chr8_38216201_38216626	0.46	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	21926	0.11
chr11_108067830_108068158	0.46	ATM	ataxia telangiectasia mutated	25217	0.14
chr8_134071429_134072001	0.45	SLA	Src-like-adaptor	888	0.68
chr1_171464835_171464991	0.45	ENSG00000239373	.	3363	0.2
chr14_23005055_23005206	0.44	TRAJ15	T cell receptor alpha joining 15	6550	0.11
chr20_43608369_43608637	0.44	STK4	serine/threonine kinase 4	13336	0.14
chr1_179269215_179269372	0.44	SOAT1	sterol O-acyltransferase 1	5838	0.22
chrX_131151133_131151349	0.44	MST4	Serine/threonine-protein kinase MST4	6052	0.23
chr9_92077290_92077553	0.44	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	6553	0.25
chr12_9909080_9909231	0.43	CD69	CD69 molecule	4342	0.18
chr1_169661653_169661807	0.43	SELL	selectin L	19109	0.18
chrX_13092624_13093057	0.43	FAM9C	family with sequence similarity 9, member C	30039	0.22
chr1_150048309_150048559	0.42	VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)	8549	0.17
chr10_11236479_11236664	0.42	RP3-323N1.2		23232	0.2
chr5_158626186_158626345	0.42	RNF145	ring finger protein 145	8377	0.18
chr10_14599434_14599610	0.42	FAM107B	family with sequence similarity 107, member B	1343	0.53
chr4_140446686_140447128	0.42	SETD7	SET domain containing (lysine methyltransferase) 7	30455	0.14
chr16_29036830_29037118	0.41	CTB-134H23.2	Uncharacterized protein	12949	0.1
chr6_143254515_143254784	0.40	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	11689	0.26
chr18_13421979_13422167	0.40	LDLRAD4-AS1	LDLRAD4 antisense RNA 1	5406	0.15
chr2_144990703_144990900	0.40	GTDC1	glycosyltransferase-like domain containing 1	2503	0.44
chr1_100830194_100830345	0.40	CDC14A	cell division cycle 14A	11764	0.18
chr1_27940236_27940387	0.40	AHDC1	AT hook, DNA binding motif, containing 1	10168	0.14
chr10_6096471_6096850	0.40	IL2RA	interleukin 2 receptor, alpha	7593	0.15
chr2_70866875_70867036	0.40	AC007395.3		47319	0.13
chr1_198606566_198606750	0.40	PTPRC	protein tyrosine phosphatase, receptor type, C	1143	0.59
chr4_40614638_40614789	0.40	RBM47	RNA binding motif protein 47	17168	0.24
chr1_110048858_110049009	0.40	AMIGO1	adhesion molecule with Ig-like domain 1	3371	0.13
chr5_66517231_66517569	0.40	CD180	CD180 molecule	24773	0.25
chr8_128312312_128312463	0.40	POU5F1B	POU class 5 homeobox 1B	114148	0.07
chr1_198667005_198667192	0.39	RP11-553K8.5		30908	0.21
chr4_39031558_39031738	0.39	TMEM156	transmembrane protein 156	2393	0.31
chr2_65347166_65347317	0.39	RAB1A	RAB1A, member RAS oncogene family	9994	0.2
chr17_46516656_46516816	0.39	SKAP1	src kinase associated phosphoprotein 1	9155	0.14
chr5_49997563_49997796	0.39	PARP8	poly (ADP-ribose) polymerase family, member 8	34288	0.25
chr2_149488876_149489027	0.39	EPC2	enhancer of polycomb homolog 2 (Drosophila)	41168	0.19
chr7_127644541_127644692	0.39	LRRC4	leucine rich repeat containing 4	26442	0.21
chr5_74320015_74320252	0.39	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	6591	0.29
chr1_28217565_28217790	0.39	RPA2	replication protein A2, 32kDa	5919	0.13
chr20_47394311_47394486	0.39	ENSG00000251876	.	38413	0.18
chr2_198105672_198105961	0.39	ANKRD44	ankyrin repeat domain 44	43054	0.13
chr20_47430189_47430589	0.39	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	14031	0.26
chr5_88737604_88737755	0.39	MEF2C-AS1	MEF2C antisense RNA 1	23055	0.29
chr8_19331197_19331348	0.39	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	128104	0.06
chr5_96345721_96346249	0.38	ENSG00000200884	.	47524	0.12
chr2_30858923_30859074	0.38	CAPN13	calpain 13	171313	0.03
chr15_60857368_60857598	0.38	RORA	RAR-related orphan receptor A	27257	0.17
chr1_167595896_167596068	0.38	RCSD1	RCSD domain containing 1	3348	0.24
chr7_37358256_37358544	0.38	ELMO1	engulfment and cell motility 1	23967	0.2
chr5_157421181_157421332	0.38	ENSG00000222626	.	17292	0.27
chr2_36473322_36473473	0.38	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	109672	0.07
chr3_15577888_15578116	0.38	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	14744	0.14
chr7_157368869_157369128	0.38	ENSG00000207960	.	1884	0.37
chr3_180636737_180636930	0.38	FXR1	fragile X mental retardation, autosomal homolog 1	3585	0.28
chr21_32553088_32553598	0.38	TIAM1	T-cell lymphoma invasion and metastasis 1	50804	0.17
chr7_151046492_151046873	0.38	NUB1	negative regulator of ubiquitin-like proteins 1	4251	0.18
chr1_206725511_206725875	0.38	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	4800	0.19
chr3_136639103_136639532	0.37	NCK1	NCK adaptor protein 1	7564	0.2
chr3_45783345_45783844	0.37	ENSG00000244357	.	573	0.74
chr10_52192809_52192960	0.37	RP11-512N4.2		39690	0.15
chr3_5506047_5506247	0.37	ENSG00000241227	.	211239	0.02
chr6_152023478_152023738	0.37	ESR1	estrogen receptor 1	11977	0.26
chr2_191874138_191874289	0.37	STAT1	signal transducer and activator of transcription 1, 91kDa	4100	0.2
chrX_48533482_48533772	0.37	WAS	Wiskott-Aldrich syndrome	1358	0.32
chr14_61819833_61820004	0.37	PRKCH	protein kinase C, eta	5309	0.24
chr2_46667275_46667426	0.37	ENSG00000241791	.	8300	0.2
chr1_41159617_41159853	0.37	NFYC	nuclear transcription factor Y, gamma	1773	0.26
chr3_187717370_187717716	0.37	LPP	LIM domain containing preferred translocation partner in lipoma	153529	0.04
chr7_35687826_35688061	0.37	HERPUD2	HERPUD family member 2	46233	0.16
chr2_69064118_69064305	0.36	AC097495.2		2075	0.33
chr14_71455194_71455760	0.36	PCNX	pecanex homolog (Drosophila)	24271	0.26
chr5_39275310_39275719	0.36	FYB	FYN binding protein	884	0.72
chr14_106479881_106480119	0.36	IGHV4-4	immunoglobulin heavy variable 4-4	1397	0.14
chr2_103035509_103035977	0.36	IL18RAP	interleukin 18 receptor accessory protein	162	0.94
chr21_32556722_32556949	0.36	TIAM1	T-cell lymphoma invasion and metastasis 1	54296	0.16
chr12_94599805_94600029	0.36	RP11-74K11.2		20097	0.19
chr6_24924695_24924972	0.36	FAM65B	family with sequence similarity 65, member B	11355	0.23
chr1_110116943_110117167	0.36	ENSG00000206832	.	17207	0.08
chr3_112692043_112692264	0.36	CD200R1	CD200 receptor 1	1606	0.33
chr7_50196159_50196415	0.36	AC020743.2		13868	0.22
chr12_47706563_47706714	0.36	ENSG00000199566	.	33442	0.16
chr6_37143189_37143451	0.36	PIM1	pim-1 oncogene	5341	0.2
chr3_169892129_169892280	0.35	PHC3	polyhomeotic homolog 3 (Drosophila)	7312	0.18
chr1_226821118_226821338	0.35	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	26143	0.18
chr2_85536506_85536752	0.35	ENSG00000221579	.	10472	0.11
chr6_157421506_157421759	0.35	RP1-137K2.2		19208	0.25
chr13_108924725_108924876	0.35	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	2556	0.31
chr3_109524622_109524801	0.35	ENSG00000265956	.	203036	0.03
chr16_79126975_79127217	0.35	RP11-556H2.3		3149	0.25
chr4_174831660_174831811	0.35	FBXO8	F-box protein 8	373079	0.01
chr13_96359567_96359723	0.35	ENSG00000251901	.	7387	0.24
chr13_41057160_41057311	0.35	AL133318.1	Uncharacterized protein	54088	0.15
chr6_112131394_112131626	0.35	FYN	FYN oncogene related to SRC, FGR, YES	9771	0.28
chr12_11933211_11933362	0.35	ETV6	ets variant 6	27851	0.24
chr15_78338703_78338858	0.35	ENSG00000221476	.	7907	0.14
chr1_174476857_174477008	0.35	GPR52	G protein-coupled receptor 52	59720	0.15
chr2_128147111_128147262	0.35	MAP3K2	mitogen-activated protein kinase kinase kinase 2	1145	0.46
chr12_59973604_59973755	0.35	ENSG00000202471	.	7045	0.19
chr14_75605037_75605385	0.35	NEK9	NIMA-related kinase 9	11164	0.14
chr4_184949026_184949285	0.35	STOX2	storkhead box 2	26677	0.21
chr1_193091860_193092090	0.35	CDC73	cell division cycle 73	828	0.54
chr2_85084585_85084736	0.35	TRABD2A	TraB domain containing 2A	23546	0.18
chr6_167492899_167493153	0.35	CCR6	chemokine (C-C motif) receptor 6	32269	0.15
chr3_13052568_13052850	0.35	IQSEC1	IQ motif and Sec7 domain 1	24173	0.24
chr20_16689392_16689732	0.34	SNRPB2	small nuclear ribonucleoprotein polypeptide B	21044	0.17
chr21_38610498_38610677	0.34	ENSG00000263969	.	22681	0.13
chr3_20146029_20146246	0.34	ENSG00000266745	.	32920	0.15
chr2_99445353_99445801	0.34	ENSG00000238830	.	11622	0.21
chr15_101061308_101061579	0.34	CERS3	ceramide synthase 3	23033	0.14
chr4_114614482_114614847	0.34	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	67560	0.14
chr7_8022696_8022847	0.34	AC006042.7		13237	0.18
chr14_53773006_53773157	0.34	RP11-547D23.1		153009	0.04
chr5_169763450_169763640	0.34	KCNIP1	Kv channel interacting protein 1	16946	0.18
chr10_26737380_26737571	0.34	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	10121	0.27
chr12_106701720_106701893	0.34	CKAP4	cytoskeleton-associated protein 4	3749	0.2
chr7_104948469_104948620	0.34	RP4-778K6.3		3820	0.23
chr3_27401268_27401649	0.34	ENSG00000221573	.	2691	0.28
chr10_50391833_50391988	0.34	C10orf128	chromosome 10 open reading frame 128	4447	0.22
chr3_183903097_183903578	0.34	ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	474	0.67
chr20_34298001_34298412	0.34	ENSG00000238549	.	6187	0.11
chr10_121291567_121291718	0.34	RGS10	regulator of G-protein signaling 10	4403	0.28
chr20_56025782_56025952	0.33	RP4-800J21.3		57749	0.09
chr11_81674020_81674171	0.33	ENSG00000264110	.	72217	0.14
chrX_9308357_9308644	0.33	TBL1X	transducin (beta)-like 1X-linked	122835	0.06
chr2_175419109_175419332	0.33	ENSG00000206965	.	3580	0.19
chr6_24992351_24992572	0.33	ENSG00000244618	.	39049	0.14
chr6_84581716_84581867	0.33	CYB5R4	cytochrome b5 reductase 4	12416	0.24
chrX_41559199_41559350	0.33	GPR34	G protein-coupled receptor 34	11015	0.17
chr17_46503996_46504323	0.33	SKAP1	src kinase associated phosphoprotein 1	3393	0.19
chr7_130725808_130725959	0.33	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	11426	0.21
chr12_14567998_14568163	0.33	ATF7IP	activating transcription factor 7 interacting protein	1767	0.44
chr14_94422346_94422789	0.33	ASB2	ankyrin repeat and SOCS box containing 2	642	0.66
chr6_135517535_135517686	0.33	MYB-AS1	MYB antisense RNA 1	477	0.8
chr3_135875257_135875408	0.33	MSL2	male-specific lethal 2 homolog (Drosophila)	38064	0.18
chr1_29271719_29271945	0.33	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	30741	0.15
chr22_40314840_40314991	0.33	GRAP2	GRB2-related adaptor protein 2	7680	0.18
chr1_160808603_160808908	0.33	CD244	CD244 molecule, natural killer cell receptor 2B4	23735	0.13
chr3_186742669_186742820	0.33	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	268	0.94
chr4_119200361_119200583	0.33	ENSG00000269893	.	127	0.98
chr11_11158749_11159001	0.33	RP11-567I13.1		215098	0.02
chr10_3228735_3228924	0.32	PITRM1	pitrilysin metallopeptidase 1	13826	0.24
chr6_12053312_12053463	0.32	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	37567	0.2
chr12_15723355_15723506	0.32	PTPRO	protein tyrosine phosphatase, receptor type, O	10267	0.28
chr18_3059365_3059574	0.32	ENSG00000252258	.	33905	0.13
chr4_122016905_122017056	0.32	NDNF	neuron-derived neurotrophic factor	22804	0.19
chr1_246812051_246812202	0.32	RP11-439E19.1		42951	0.14
chr2_27297539_27298497	0.32	OST4	oligosaccharyltransferase 4 homolog (S. cerevisiae)	3377	0.09
chr2_20538396_20538547	0.32	PUM2	pumilio RNA-binding family member 2	11327	0.18
chr1_93645068_93645219	0.32	CCDC18	coiled-coil domain containing 18	333	0.72
chr4_78048877_78049059	0.32	ENSG00000201641	.	22622	0.19
chr9_21024927_21025141	0.32	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	6574	0.22
chr1_116931483_116931823	0.32	AL136376.1	Uncharacterized protein	4935	0.17
chr11_2859011_2859454	0.32	KCNQ1-AS1	KCNQ1 antisense RNA 1	23566	0.13
chr6_41839689_41839840	0.32	USP49	ubiquitin specific peptidase 49	51	0.96
chr2_43018765_43019093	0.31	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	783	0.7
chr10_22544887_22545038	0.31	EBLN1	endogenous Bornavirus-like nucleoprotein 1	46012	0.13
chr2_8620238_8620557	0.31	AC011747.7		195499	0.03
chr5_75597801_75597952	0.31	RP11-466P24.6		9411	0.29
chr3_37217050_37217361	0.31	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	499	0.74
chr4_24557660_24557830	0.31	ENSG00000243005	.	7339	0.22
chr8_98660499_98660721	0.31	MTDH	metadherin	3589	0.34
chr5_148199180_148199331	0.31	ADRB2	adrenoceptor beta 2, surface	6901	0.28
chr8_97658898_97659272	0.31	CPQ	carboxypeptidase Q	1482	0.54
chr6_119221110_119221261	0.31	ASF1A	anti-silencing function 1A histone chaperone	5801	0.22
chr2_99070605_99070929	0.31	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	9354	0.24
chr1_160645609_160645760	0.31	RP11-404F10.2		2372	0.25
chr12_104865091_104865422	0.31	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	14477	0.26
chr21_38767054_38767423	0.31	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	23969	0.19
chr10_30818232_30818501	0.31	ENSG00000239744	.	26467	0.21
chr10_81951710_81952023	0.31	ANXA11	annexin A11	12381	0.2
chr4_90209518_90209853	0.31	GPRIN3	GPRIN family member 3	19476	0.27
chr2_197064930_197065081	0.31	ENSG00000239161	.	15041	0.18
chr3_3213472_3213785	0.31	CRBN	cereblon	7730	0.19
chr5_169713584_169713822	0.31	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	11528	0.22
chr3_108316037_108316188	0.31	DZIP3	DAZ interacting zinc finger protein 3	5568	0.2
chr14_31675439_31675700	0.31	HECTD1	HECT domain containing E3 ubiquitin protein ligase 1	1120	0.48
chr7_37827056_37827207	0.31	GPR141	G protein-coupled receptor 141	47135	0.16
chr15_34501219_34501425	0.31	KATNBL1	katanin p80 subunit B-like 1	890	0.55
chr7_104853981_104854132	0.31	SRPK2	SRSF protein kinase 2	55406	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.8	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.2	0.6	GO:0030223	neutrophil differentiation(GO:0030223)
0.2	0.5	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	1.0	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.4	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1	0.1	GO:0002667	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.4	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.3	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.3	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.2	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.3	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.1	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.2	GO:0003323	type B pancreatic cell development(GO:0003323)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:0040023	establishment of nucleus localization(GO:0040023)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.3	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.2	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.2	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	3.8	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.2	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0031394	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.2	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.6	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0003171	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.2	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.2	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0030540	female genitalia development(GO:0030540)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.3	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.1	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0046479	glycosphingolipid catabolic process(GO:0046479)
0.0	0.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.0	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.0	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.1	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.0	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0010586	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.6	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.1	GO:0015669	gas transport(GO:0015669)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:1903959	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) regulation of anion transmembrane transport(GO:1903959)
0.0	0.4	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.0	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.0	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.4	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.6	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:0048521	negative regulation of behavior(GO:0048521)
0.0	0.0	GO:0031058	positive regulation of histone modification(GO:0031058)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.9	GO:0006959	humoral immune response(GO:0006959)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0044068	modulation by virus of host process(GO:0019054) modulation by symbiont of host cellular process(GO:0044068)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.0	GO:0036445	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.2	GO:0014823	response to activity(GO:0014823)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.4	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.2	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.0	GO:0061339	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.6	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.0	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.2	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.3	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.1	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.3	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.1	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	0.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.1	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0030825	positive regulation of cGMP metabolic process(GO:0030825)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.0	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.1	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.2	GO:0072487	MSL complex(GO:0072487)
0.1	0.6	GO:0001772	immunological synapse(GO:0001772)
0.1	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.4	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.3	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.4	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.0	GO:0038201	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.3	GO:0034358	protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.5	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.0	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.8	GO:0019864	IgG binding(GO:0019864)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	1.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.5	GO:0030332	cyclin binding(GO:0030332)
0.1	0.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.2	GO:0004556	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1	0.3	GO:0050733	RS domain binding(GO:0050733)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	1.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.0	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.2	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.0	0.5	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.0	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.7	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0000217	DNA secondary structure binding(GO:0000217)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.2	GO:0017022	myosin binding(GO:0017022)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.0	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.2	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex

Results for HMGA2

Z-value: 1.67

Motif logo

Transcription factors associated with HMGA2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HMGA2 motif across conditions

Conditions sorted by the z-value of the HMGA2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: