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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HMX2

Z-value: 3.07

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Transcription factors associated with HMX2

Gene Symbol	Gene ID	Gene Info
HMX2 Ensembl NCBI GeneCards UniProt	ENSG00000188816.3	H6 family homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_124908838_124908989	HMX2	1275	0.420760	-0.67	4.8e-02	Click!
chr10_124901552_124901703	HMX2	6011	0.179929	-0.59	9.8e-02	Click!
chr10_124906065_124906530	HMX2	1341	0.407458	-0.52	1.5e-01	Click!
chr10_124902617_124903031	HMX2	4814	0.190465	-0.44	2.4e-01	Click!
chr10_124905622_124905885	HMX2	1885	0.309398	-0.43	2.5e-01	Click!

Activity of the HMX2 motif across conditions

Conditions sorted by the z-value of the HMX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_22723256_22723780	2.83	RP11-301N24.3		73417	0.1
chr3_188139152_188139752	2.51	LPP-AS1	LPP antisense RNA 1	147002	0.04
chr21_40683413_40684326	2.28	BRWD1	bromodomain and WD repeat domain containing 1	1627	0.24
chr6_74432714_74432936	2.18	RP11-553A21.3		26971	0.17
chr17_60074998_60075962	2.04	ENSG00000242398	.	7868	0.17
chr6_53304943_53305256	2.03	ENSG00000212065	.	16231	0.17
chr6_129966569_129967050	2.01	ARHGAP18	Rho GTPase activating protein 18	64561	0.13
chr2_47075547_47075844	1.98	AC016722.3		4940	0.18
chr15_71341987_71342266	1.89	THSD4	thrombospondin, type I, domain containing 4	47165	0.15
chr1_183578044_183578492	1.88	NCF2	neutrophil cytosolic factor 2	18257	0.16
chr6_107009635_107010133	1.84	AIM1	absent in melanoma 1	20855	0.17
chr5_77800136_77800667	1.83	LHFPL2	lipoma HMGIC fusion partner-like 2	44573	0.19
chr13_45769539_45769983	1.80	KCTD4	potassium channel tetramerization domain containing 4	909	0.6
chr4_22515546_22516022	1.78	GPR125	G protein-coupled receptor 125	1836	0.52
chr9_97567295_97567893	1.77	ENSG00000252153	.	4650	0.2
chr12_26275796_26276929	1.77	SSPN	sarcospan	1438	0.31
chr8_93978348_93978807	1.75	TRIQK	triple QxxK/R motif containing	204	0.96
chr3_128914264_128914631	1.72	CNBP	CCHC-type zinc finger, nucleic acid binding protein	11682	0.14
chr11_67979238_67979938	1.71	SUV420H1	suppressor of variegation 4-20 homolog 1 (Drosophila)	633	0.74
chr13_75343971_75344251	1.71	ENSG00000206812	.	339613	0.01
chr1_234755566_234755985	1.67	IRF2BP2	interferon regulatory factor 2 binding protein 2	10504	0.19
chr18_74188097_74188669	1.66	ZNF516	zinc finger protein 516	14352	0.17
chr17_74734284_74735284	1.60	MFSD11	major facilitator superfamily domain containing 11	631	0.43
chr12_26428456_26429005	1.60	RP11-283G6.5		3877	0.25
chr3_123476973_123477366	1.57	MYLK	myosin light chain kinase	35519	0.15
chr1_15504056_15504331	1.55	C1orf195	chromosome 1 open reading frame 195	6380	0.22
chr12_29895057_29895338	1.55	TMTC1	transmembrane and tetratricopeptide repeat containing 1	41534	0.21
chr1_39595445_39595950	1.55	ENSG00000206654	.	8982	0.17
chr20_19795785_19795937	1.54	AL121761.2	Uncharacterized protein	57182	0.12
chr5_34052813_34052964	1.54	C1QTNF3	C1q and tumor necrosis factor related protein 3	8951	0.23
chr2_43683261_43683590	1.51	ENSG00000252804	.	47979	0.17
chr2_43986548_43986990	1.50	ENSG00000252490	.	12720	0.19
chr8_38749440_38749591	1.49	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	9238	0.18
chr15_36663589_36663740	1.48	C15orf41	chromosome 15 open reading frame 41	208148	0.03
chr1_109936676_109936954	1.47	SORT1	sortilin 1	836	0.57
chr5_14191108_14191422	1.45	TRIO	trio Rho guanine nucleotide exchange factor	7358	0.33
chr4_157860731_157860908	1.45	PDGFC	platelet derived growth factor C	31236	0.19
chr9_125766060_125766211	1.44	RABGAP1	RAB GTPase activating protein 1	29653	0.12
chr7_17410528_17410788	1.44	ENSG00000199473	.	2292	0.4
chr19_1361317_1362052	1.44	MUM1	melanoma associated antigen (mutated) 1	5321	0.1
chr2_12959099_12960371	1.42	ENSG00000264370	.	82242	0.11
chr16_53244701_53244919	1.39	CHD9	chromodomain helicase DNA binding protein 9	2447	0.31
chr7_30405432_30405583	1.39	GS1-114I9.1		58781	0.11
chr2_147739330_147739481	1.39	ENSG00000238860	.	342134	0.01
chr2_9580081_9580232	1.39	CPSF3	cleavage and polyadenylation specific factor 3, 73kDa	16143	0.16
chr14_39737352_39738045	1.38	CTAGE5	CTAGE family, member 5	1080	0.35
chr18_434239_434644	1.37	RP11-720L2.2		10025	0.23
chr1_170676508_170676659	1.36	PRRX1	paired related homeobox 1	43505	0.19
chr12_105749863_105750120	1.34	C12orf75	chromosome 12 open reading frame 75	25345	0.17
chr13_80510337_80510488	1.33	SPRY2	sprouty homolog 2 (Drosophila)	403382	0.01
chr6_38230222_38230373	1.32	ENSG00000200706	.	55247	0.15
chr2_224950724_224950875	1.32	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	46763	0.17
chr2_40612222_40612511	1.30	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	45054	0.2
chr21_40192893_40193225	1.30	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	11499	0.28
chr7_40713134_40713414	1.29	AC005160.3		101883	0.08
chr3_156537447_156537706	1.28	LEKR1	leucine, glutamate and lysine rich 1	6513	0.3
chr7_80350905_80351077	1.27	CD36	CD36 molecule (thrombospondin receptor)	48299	0.19
chr9_130591213_130591484	1.25	ENSG00000222421	.	3674	0.1
chr11_61690283_61690510	1.25	RAB3IL1	RAB3A interacting protein (rabin3)-like 1	2655	0.18
chr7_80740177_80740328	1.25	AC005008.2	Uncharacterized protein	64572	0.15
chr12_26303323_26303715	1.24	SSPN	sarcospan	15619	0.18
chr5_163321011_163321256	1.24	ENSG00000251998	.	97962	0.09
chr4_170532685_170533303	1.24	NEK1	NIMA-related kinase 1	740	0.46
chr18_12598337_12598791	1.24	SPIRE1	spire-type actin nucleation factor 1	54520	0.09
chr9_74362936_74363179	1.24	TMEM2	transmembrane protein 2	20245	0.27
chr19_4506384_4506690	1.24	HDGFRP2	Hepatoma-derived growth factor-related protein 2	6911	0.09
chr1_186152875_186153258	1.23	GS1-174L6.4		6632	0.23
chr20_20374331_20374710	1.23	INSM1	insulinoma-associated 1	25755	0.22
chr4_171593437_171593770	1.23	ENSG00000251961	.	219015	0.02
chr4_184096914_184097065	1.23	ENSG00000252048	.	1095	0.48
chr5_153826475_153827364	1.23	SAP30L	SAP30-like	814	0.51
chr20_52556645_52557141	1.22	AC005220.3		194	0.96
chr12_22435543_22435694	1.22	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	33638	0.22
chr5_71437056_71437207	1.22	ENSG00000264099	.	28163	0.2
chr7_151362944_151363227	1.21	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	32834	0.19
chr1_203533572_203533723	1.21	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	62042	0.11
chr4_95470032_95470452	1.21	PDLIM5	PDZ and LIM domain 5	25366	0.27
chr4_48332474_48332625	1.21	SLAIN2	SLAIN motif family, member 2	10790	0.24
chr8_48392391_48392850	1.21	SPIDR	scaffolding protein involved in DNA repair	39657	0.18
chr3_93562236_93562537	1.21	ENSG00000251727	.	222	0.96
chr4_123704879_123705044	1.20	FGF2	fibroblast growth factor 2 (basic)	42902	0.13
chr5_158179607_158179937	1.20	CTD-2363C16.1		230242	0.02
chr10_36110915_36111066	1.20	FZD8	frizzled family receptor 8	180628	0.03
chr14_69501591_69501923	1.19	ACTN1-AS1	ACTN1 antisense RNA 1	54999	0.12
chr8_17082580_17082774	1.19	CNOT7	CCR4-NOT transcription complex, subunit 7	9692	0.21
chr3_32185972_32186147	1.18	ENSG00000238646	.	28089	0.16
chr6_170713316_170713467	1.18	RP1-140C12.2		9836	0.24
chr10_114021204_114021502	1.18	TECTB	tectorin beta	22140	0.23
chr1_101455176_101455327	1.17	AC093157.1	Uncharacterized protein	510	0.72
chr20_10286775_10287859	1.17	ENSG00000211588	.	55561	0.13
chr6_140264980_140265131	1.16	ENSG00000252107	.	214776	0.02
chr6_103680064_103680234	1.16	ENSG00000202283	.	350861	0.01
chr22_28144785_28145032	1.16	RP11-375H17.1		32440	0.2
chr11_110019213_110019563	1.16	ZC3H12C	zinc finger CCCH-type containing 12C	12809	0.3
chr9_37761275_37761426	1.16	TRMT10B	tRNA methyltransferase 10 homolog B (S. cerevisiae)	7536	0.18
chr4_119826460_119826775	1.16	SYNPO2	synaptopodin 2	16425	0.26
chr16_79646883_79647034	1.16	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	12347	0.28
chr11_9172322_9172473	1.15	DENND5A	DENN/MADD domain containing 5A	1557	0.4
chr5_124744953_124745179	1.15	ENSG00000222107	.	58242	0.17
chr18_53901184_53901335	1.15	ENSG00000201816	.	154434	0.04
chr4_169526190_169526341	1.14	PALLD	palladin, cytoskeletal associated protein	26501	0.19
chr9_127471212_127471497	1.14	ENSG00000207737	.	15365	0.14
chr3_124959622_124959984	1.13	SLC12A8	solute carrier family 12, member 8	28194	0.2
chr6_137567831_137568175	1.13	IFNGR1	interferon gamma receptor 1	27417	0.23
chr22_39889600_39889751	1.13	MIEF1	mitochondrial elongation factor 1	6430	0.14
chr1_113067430_113067581	1.13	RP4-671G15.2		6442	0.19
chr7_46792365_46792593	1.12	AC011294.3	Uncharacterized protein	55759	0.18
chr15_48718889_48719040	1.12	DUT	deoxyuridine triphosphatase	94361	0.07
chr15_82422353_82422648	1.11	RP11-597K23.2	Uncharacterized protein	41468	0.14
chr1_52215707_52215947	1.11	OSBPL9	oxysterol binding protein-like 9	20121	0.14
chr4_85602887_85603189	1.11	ENSG00000239466	.	6133	0.27
chr14_59804366_59804548	1.11	ENSG00000252869	.	62284	0.12
chr13_31443663_31443814	1.10	MEDAG	mesenteric estrogen-dependent adipogenesis	36590	0.17
chr10_54412447_54412741	1.10	RP11-556E13.1		91729	0.09
chr1_179146592_179146743	1.10	ENSG00000212338	.	18941	0.17
chr6_126135548_126136266	1.10	NCOA7	nuclear receptor coactivator 7	457	0.81
chr1_25666704_25667414	1.10	ENSG00000252515	.	403	0.75
chr5_53387008_53387159	1.10	ENSG00000265421	.	15670	0.24
chr1_181047003_181047287	1.09	IER5	immediate early response 5	10493	0.21
chr6_22880503_22880654	1.09	ENSG00000207394	.	244737	0.02
chr7_111724278_111724664	1.09	DOCK4	dedicator of cytokinesis 4	80285	0.1
chr3_114959246_114959397	1.09	ZBTB20	zinc finger and BTB domain containing 20	93203	0.1
chr16_66604326_66604620	1.09	CMTM1	CKLF-like MARVEL transmembrane domain containing 1	4056	0.11
chr15_85458028_85458261	1.09	ENSG00000207037	.	23609	0.13
chr6_42192546_42192697	1.09	MRPS10	mitochondrial ribosomal protein S10	7018	0.19
chr8_118411718_118411869	1.08	ENSG00000252852	.	86026	0.1
chr22_46943714_46943865	1.08	RP3-439F8.1		6397	0.2
chr3_149814811_149814962	1.08	RP11-167H9.4		656	0.73
chr11_9774128_9774293	1.08	SBF2-AS1	SBF2 antisense RNA 1	5629	0.19
chr4_141446173_141446497	1.08	ELMOD2	ELMO/CED-12 domain containing 2	745	0.66
chr3_127778796_127778947	1.08	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	7269	0.16
chr8_117333837_117333988	1.08	ENSG00000264815	.	34324	0.24
chr6_151530649_151530800	1.07	ENSG00000238616	.	8248	0.17
chr18_42747380_42747531	1.07	RP11-846C15.2		13624	0.26
chr12_12037558_12037709	1.07	ETV6	ets variant 6	1238	0.62
chr3_58034413_58034564	1.07	FLNB	filamin B, beta	29568	0.21
chr5_60698537_60698930	1.07	ZSWIM6	zinc finger, SWIM-type containing 6	70633	0.12
chr6_16800808_16801152	1.07	RP1-151F17.1		38837	0.19
chr5_56467993_56468852	1.07	GPBP1	GC-rich promoter binding protein 1	1353	0.47
chr8_41575770_41575921	1.06	ANK1	ankyrin 1, erythrocytic	12148	0.18
chr8_17600949_17601376	1.06	ENSG00000212280	.	4465	0.2
chr3_23366610_23366849	1.06	ENSG00000206728	.	51431	0.15
chr11_19911790_19911941	1.06	NAV2-AS3	NAV2 antisense RNA 3	91018	0.08
chr17_41668721_41668956	1.06	ETV4	ets variant 4	11850	0.16
chr11_35512548_35512699	1.06	PAMR1	peptidase domain containing associated with muscle regeneration 1	34528	0.18
chr9_13387407_13387558	1.06	MPDZ	multiple PDZ domain protein	107893	0.07
chr11_9775679_9775937	1.06	SBF2-AS1	SBF2 antisense RNA 1	4031	0.21
chr2_224683617_224683768	1.06	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	18509	0.26
chr10_76262453_76262795	1.05	RP11-46O21.2		26452	0.22
chr2_224797142_224797406	1.05	WDFY1	WD repeat and FYVE domain containing 1	12800	0.19
chr1_115844585_115844736	1.05	RP4-663N10.1		19005	0.23
chr2_208744437_208744768	1.05	AC083900.1		9963	0.22
chr8_97583664_97583930	1.04	SDC2	syndecan 2	8780	0.28
chr2_172619572_172619723	1.04	AC068039.4		10345	0.22
chr10_69895341_69895492	1.04	ENSG00000222371	.	22420	0.17
chr3_45230194_45230345	1.03	TMEM158	transmembrane protein 158 (gene/pseudogene)	37501	0.15
chr6_1821253_1821404	1.03	FOXC1	forkhead box C1	210647	0.02
chr11_17867327_17867615	1.03	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	109951	0.06
chr11_100748119_100748270	1.03	ARHGAP42	Rho GTPase activating protein 42	36037	0.15
chr6_160016990_160017141	1.03	SOD2	superoxide dismutase 2, mitochondrial	97195	0.07
chr7_107331221_107331712	1.03	SLC26A4	solute carrier family 26 (anion exchanger), member 4	869	0.57
chr1_94018188_94018555	1.03	FNBP1L	formin binding protein 1-like	23104	0.17
chr4_139875717_139875868	1.03	RP11-371F15.3		16657	0.2
chr13_31294257_31294613	1.02	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	15210	0.26
chr7_102532238_102532538	1.02	LRRC17	leucine rich repeat containing 17	21050	0.16
chr6_52373200_52373495	1.02	TRAM2	translocation associated membrane protein 2	68366	0.11
chr3_188995375_188995558	1.02	TPRG1-AS2	TPRG1 antisense RNA 2	37083	0.21
chr14_69535729_69536049	1.02	ENSG00000206768	.	74781	0.09
chr6_139729934_139730085	1.02	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	34252	0.22
chr18_60449347_60449701	1.02	AC015989.1	Uncharacterized protein	41899	0.14
chr8_71471870_71472021	1.02	AC120194.1		13736	0.17
chr11_101986710_101986861	1.02	YAP1	Yes-associated protein 1	3540	0.21
chr5_141998017_141998291	1.02	FGF1	fibroblast growth factor 1 (acidic)	2753	0.29
chr3_17674402_17674598	1.02	TBC1D5	TBC1 domain family, member 5	9092	0.27
chr11_101733462_101733613	1.01	ANGPTL5	angiopoietin-like 5	45128	0.16
chr12_27768637_27769056	1.01	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	16565	0.2
chr20_43169764_43169915	1.01	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	9269	0.15
chr16_54480360_54480511	1.01	ENSG00000264079	.	102873	0.08
chr3_120155257_120155408	1.01	FSTL1	follistatin-like 1	14506	0.24
chr7_115872460_115873536	1.00	AC073130.3		6307	0.23
chr5_97644195_97644346	1.00	ENSG00000223053	.	330665	0.01
chr3_160113132_160113306	1.00	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)	3776	0.16
chr2_46547386_46547537	1.00	EPAS1	endothelial PAS domain protein 1	22920	0.23
chr1_182998943_182999094	1.00	LAMC1	laminin, gamma 1 (formerly LAMB2)	6423	0.22
chr4_177700103_177700254	1.00	VEGFC	vascular endothelial growth factor C	13703	0.29
chr12_66322607_66323042	1.00	AC090673.2	Uncharacterized protein	4857	0.21
chr17_20840161_20840312	1.00	RP11-344E13.3		1597	0.25
chr2_189849137_189849288	1.00	ENSG00000221502	.	6394	0.23
chr2_15309647_15309798	1.00	NBAS	neuroblastoma amplified sequence	20799	0.29
chr11_65670977_65671147	0.99	FOSL1	FOS-like antigen 1	3018	0.11
chr6_45042698_45042910	0.99	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	119557	0.06
chr10_91954011_91954162	0.99	ENSG00000222451	.	30369	0.26
chr17_11992757_11992908	0.99	ENSG00000266297	.	7616	0.24
chr4_166793804_166794189	0.99	TLL1	tolloid-like 1	414	0.92
chr3_142695571_142696006	0.99	RP11-372E1.6		12449	0.15
chr3_128267799_128268165	0.99	C3orf27	chromosome 3 open reading frame 27	26947	0.16
chr3_110133205_110133356	0.99	ENSG00000221206	.	137532	0.05
chr12_118798649_118798918	0.99	TAOK3	TAO kinase 3	1258	0.54
chr2_237652695_237652846	0.99	ACKR3	atypical chemokine receptor 3	174486	0.03
chr9_33107993_33108144	0.99	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	20129	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.5	1.4	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.5	1.8	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.4	3.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4	2.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4	1.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.4	1.1	GO:0071436	sodium ion export(GO:0071436)
0.3	1.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.3	1.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3	1.0	GO:0008215	spermine metabolic process(GO:0008215)
0.3	1.9	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.3	0.9	GO:0061072	iris morphogenesis(GO:0061072)
0.3	0.9	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.3	0.9	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.3	1.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.3	1.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.3	0.6	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3	1.6	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.3	0.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.3	0.8	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.3	0.8	GO:0007144	female meiosis I(GO:0007144)
0.3	0.3	GO:0072191	ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.2	0.5	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2	0.7	GO:0071277	cellular response to calcium ion(GO:0071277)
0.2	0.7	GO:0007132	meiotic metaphase I(GO:0007132)
0.2	0.5	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.7	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	0.4	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.2	0.6	GO:1903332	regulation of protein folding(GO:1903332)
0.2	1.5	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.2	0.2	GO:0035412	catenin import into nucleus(GO:0035411) regulation of catenin import into nucleus(GO:0035412)
0.2	0.8	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.2	0.8	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	1.0	GO:0007386	compartment pattern specification(GO:0007386)
0.2	1.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	0.6	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.6	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.2	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.2	0.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.2	0.9	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	1.4	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2	0.4	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.2	0.5	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2	1.4	GO:0006108	malate metabolic process(GO:0006108)
0.2	0.2	GO:0060437	lung growth(GO:0060437)
0.2	0.3	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2	0.5	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	0.5	GO:0048388	endosomal lumen acidification(GO:0048388)
0.2	0.5	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.2	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2	0.5	GO:0045112	integrin biosynthetic process(GO:0045112)
0.2	0.5	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.2	0.5	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	1.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.6	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.4	GO:0010193	response to ozone(GO:0010193)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.7	GO:0060840	artery development(GO:0060840)
0.1	0.6	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.6	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	1.0	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.6	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.4	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.4	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.3	GO:0051284	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.8	GO:0015871	choline transport(GO:0015871)
0.1	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	1.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.5	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.4	GO:0060242	contact inhibition(GO:0060242)
0.1	0.4	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	1.3	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.4	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.5	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.1	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.1	0.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.4	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.4	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:0030185	nitric oxide transport(GO:0030185)
0.1	0.5	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.5	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.6	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.4	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.4	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	1.6	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.4	GO:0008218	bioluminescence(GO:0008218)
0.1	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	0.5	GO:0060081	membrane hyperpolarization(GO:0060081)
0.1	0.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.2	GO:0060174	limb bud formation(GO:0060174)
0.1	0.1	GO:0060197	cloaca development(GO:0035844) skin morphogenesis(GO:0043589) cloacal septation(GO:0060197)
0.1	0.2	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.1	0.2	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	2.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.7	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	0.7	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.4	GO:0018101	protein citrullination(GO:0018101)
0.1	0.4	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.1	GO:0050955	sensory perception of temperature stimulus(GO:0050951) thermoception(GO:0050955)
0.1	0.9	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1	0.4	GO:0002076	osteoblast development(GO:0002076)
0.1	1.2	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.3	GO:0042482	positive regulation of odontogenesis(GO:0042482)
0.1	1.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.3	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.6	GO:0010092	organ induction(GO:0001759) specification of organ identity(GO:0010092)
0.1	0.2	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.1	GO:0071600	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.1	1.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1	0.5	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.1	0.4	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.5	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.7	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.4	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	2.7	GO:0048813	dendrite morphogenesis(GO:0048813)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	0.3	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.9	GO:0007603	phototransduction, visible light(GO:0007603)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.3	GO:0048539	bone marrow development(GO:0048539)
0.1	0.3	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.4	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.2	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.1	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.6	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.5	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1	0.6	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	0.3	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.3	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	0.2	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.1	0.8	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.5	GO:0007567	parturition(GO:0007567)
0.1	0.5	GO:0045116	protein neddylation(GO:0045116)
0.1	0.2	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1	0.3	GO:0090224	regulation of spindle organization(GO:0090224)
0.1	0.2	GO:0019532	oxalate transport(GO:0019532)
0.1	0.2	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.1	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.1	GO:0051323	mitotic metaphase(GO:0000089) metaphase(GO:0051323)
0.1	0.3	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	0.4	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.3	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	1.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0060435	bronchiole development(GO:0060435)
0.1	1.0	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.2	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.1	0.5	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.2	GO:0046599	regulation of centriole replication(GO:0046599)
0.1	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.9	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.1	0.3	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.1	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.2	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.3	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.3	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	0.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.1	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.8	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.1	0.1	GO:0001757	somite specification(GO:0001757)
0.1	0.1	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.2	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	1.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.1	0.3	GO:0008228	opsonization(GO:0008228)
0.1	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.4	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.1	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.1	0.5	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.1	0.3	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.1	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.1	0.1	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	0.2	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.2	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.1	0.2	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.1	0.6	GO:0035329	hippo signaling(GO:0035329)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.6	GO:0030728	ovulation(GO:0030728)
0.1	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1	0.1	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.7	GO:0008272	sulfate transport(GO:0008272)
0.1	0.3	GO:0006547	histidine metabolic process(GO:0006547)
0.1	0.1	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1	0.2	GO:0097035	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) regulation of membrane lipid distribution(GO:0097035)
0.1	0.4	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.2	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.1	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.1	0.2	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.5	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.1	0.2	GO:0034695	response to prostaglandin E(GO:0034695)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.5	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	1.0	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.0	0.2	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.3	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.0	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
0.0	0.3	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.4	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0006563	L-serine metabolic process(GO:0006563)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	1.0	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.2	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.2	GO:0030238	male sex determination(GO:0030238)
0.0	0.5	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0051135	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.0	0.3	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.0	0.0	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.3	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.2	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.4	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.3	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.2	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0009264	deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.3	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.2	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.2	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.4	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.2	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0051608	histamine secretion(GO:0001821) histamine transport(GO:0051608)
0.0	0.0	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.3	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.3	GO:0098764	meiosis I cell cycle phase(GO:0098764)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.4	GO:0001508	action potential(GO:0001508)
0.0	0.2	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.2	GO:0009219	pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.0	0.1	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0090273	somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0	0.3	GO:0015695	organic cation transport(GO:0015695)
0.0	0.4	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.0	GO:1902224	cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952) ketone body metabolic process(GO:1902224)
0.0	0.2	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.2	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0044851	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.4	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	3.0	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.6	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.0	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.0	GO:0044268	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.1	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.4	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	1.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0060349	bone morphogenesis(GO:0060349)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.3	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0009948	anterior/posterior axis specification(GO:0009948)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.1	GO:0009584	detection of visible light(GO:0009584)
0.0	0.0	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.0	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.2	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.0	1.8	GO:0006936	muscle contraction(GO:0006936)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.3	GO:0006821	chloride transport(GO:0006821)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.1	GO:0051956	negative regulation of organic acid transport(GO:0032891) negative regulation of amino acid transport(GO:0051956)
0.0	0.3	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.4	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.0	GO:0060914	heart formation(GO:0060914)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.0	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.0	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:1900076	regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0	0.0	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.4	1.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	1.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.6	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.8	GO:0033268	node of Ranvier(GO:0033268)
0.2	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.2	0.7	GO:0032059	bleb(GO:0032059)
0.2	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.7	GO:0005915	zonula adherens(GO:0005915)
0.1	0.7	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.8	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.4	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	1.0	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	1.0	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.4	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.8	GO:0005916	fascia adherens(GO:0005916)
0.1	0.8	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.6	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	1.1	GO:0030315	T-tubule(GO:0030315)
0.1	0.6	GO:0001527	microfibril(GO:0001527)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.6	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	1.7	GO:0005811	lipid particle(GO:0005811)
0.1	0.3	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	0.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.3	GO:0031045	dense core granule(GO:0031045)
0.1	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.6	GO:0002102	podosome(GO:0002102)
0.1	1.4	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.7	GO:0008091	spectrin(GO:0008091)
0.1	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.8	GO:0005581	collagen trimer(GO:0005581)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	1.9	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.4	GO:0051233	spindle midzone(GO:0051233)
0.1	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.1	GO:0045298	tubulin complex(GO:0045298)
0.1	0.3	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	1.1	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.5	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	4.3	GO:0030027	lamellipodium(GO:0030027)
0.1	0.3	GO:0030990	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.1	0.1	GO:0032432	actin filament bundle(GO:0032432)
0.1	0.1	GO:0033643	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	1.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	1.4	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.6	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	3.0	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.5	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.3	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	9.0	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	1.6	GO:0030426	growth cone(GO:0030426)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.4	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	2.1	GO:0005925	focal adhesion(GO:0005925)
0.0	0.5	GO:0070161	anchoring junction(GO:0070161)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.5	GO:0030018	Z disc(GO:0030018)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.5	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.0	GO:0042599	lamellar body(GO:0042599)
0.0	0.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.6	GO:0042383	sarcolemma(GO:0042383)
0.0	0.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.3	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	2.8	GO:0016324	apical plasma membrane(GO:0016324)
0.0	1.2	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.0	GO:0001939	female pronucleus(GO:0001939)
0.0	0.6	GO:0044449	contractile fiber part(GO:0044449)
0.0	0.0	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	1.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.4	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	6.5	GO:0005615	extracellular space(GO:0005615)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0071546	pi-body(GO:0071546)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.7	2.0	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.6	2.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.5	1.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3	1.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.3	1.7	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.3	1.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	1.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3	1.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	1.2	GO:0004470	malic enzyme activity(GO:0004470)
0.3	1.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.3	1.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.3	1.4	GO:0042805	actinin binding(GO:0042805)
0.3	1.9	GO:0017166	vinculin binding(GO:0017166)
0.3	1.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3	0.8	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	1.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	1.6	GO:0005110	frizzled-2 binding(GO:0005110)
0.2	0.7	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	0.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	0.6	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.2	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	0.6	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	0.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2	0.6	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	0.5	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.5	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	0.5	GO:0050693	LBD domain binding(GO:0050693)
0.2	0.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	0.7	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2	0.5	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2	1.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2	0.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2	0.6	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.5	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.2	0.9	GO:0004075	biotin carboxylase activity(GO:0004075)
0.2	0.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.6	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	2.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.7	GO:0015368	calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.7	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.8	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.7	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.5	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.5	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.5	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.4	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.4	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.6	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.7	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	2.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	1.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	1.0	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.5	GO:0005534	galactose binding(GO:0005534)
0.1	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0004803	transposase activity(GO:0004803)
0.1	0.3	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	1.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.3	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	0.4	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.7	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.7	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.3	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	1.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.7	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.5	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.2	GO:0008252	nucleotidase activity(GO:0008252)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	5.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1	0.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.5	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	1.1	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.1	GO:0033265	cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1	1.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.6	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	1.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.5	GO:0046790	virion binding(GO:0046790)
0.1	0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.1	0.8	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	0.2	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	0.7	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1	0.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	1.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.4	GO:0030507	spectrin binding(GO:0030507)
0.1	0.4	GO:0048038	quinone binding(GO:0048038)
0.1	0.2	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.3	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.6	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	0.4	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1	0.3	GO:0001846	opsonin binding(GO:0001846)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.2	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.5	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.1	GO:0070052	collagen V binding(GO:0070052)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.9	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.2	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.4	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.5	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.5	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.3	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0032190	acrosin binding(GO:0032190)
0.0	0.3	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.3	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.4	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.5	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.5	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.3	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	1.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.3	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.2	GO:0005536	glucose binding(GO:0005536)
0.0	3.5	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.5	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.3	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	2.3	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.4	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	1.0	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	1.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121) nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.7	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.3	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0016684	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.3	GO:0016836	hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	1.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	2.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	4.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.3	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	0.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	1.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	1.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	2.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	1.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	1.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	9.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.7	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	4.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	6.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.3	3.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	0.2	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.2	4.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	0.1	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.1	1.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	5.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.5	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	2.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	0.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	0.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.0	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.4	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.0	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.6	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.4	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.6	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	1.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling

Results for HMX2

Z-value: 3.07

Motif logo

Transcription factors associated with HMX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HMX2 motif across conditions

Conditions sorted by the z-value of the HMX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: