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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HNF1A_HNF1B

Z-value: 0.80

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
HNF1A
ENSG00000135100.13 HNF1 homeobox A
HNF1B
ENSG00000108753.8 HNF1 homeobox B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_36135419_36135570HNF1B302570.150237-0.891.1e-03Click!
chr17_36112352_36112607HNF1B72420.1921900.801.0e-02Click!
chr17_36122844_36122995HNF1B176820.173448-0.781.4e-02Click!
chr17_36121536_36121745HNF1B164030.175492-0.703.5e-02Click!
chr17_36124947_36125098HNF1B197850.169880-0.637.1e-02Click!

Activity of the HNF1A_HNF1B motif across conditions

Conditions sorted by the z-value of the HNF1A_HNF1B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_69405435_69405631 0.59 ACTN1
 actinin, alpha 1
 8732
 0.24
chr1_68214159_68214518 0.46 ENSG00000238778
 .
 23998
 0.19
chr10_97849004_97849155 0.45 ENTPD1-AS1
 ENTPD1 antisense RNA 1
 833
 0.59
chr9_20320271_20320422 0.43 ENSG00000221744
 .
 25344
 0.21
chr1_181121299_181121450 0.39 IER5
 immediate early response 5
 63736
 0.13
chr7_37071372_37071523 0.39 ELMO1-AS1
 ELMO1 antisense RNA 1
 34046
 0.17
chr10_29924859_29925052 0.39 SVIL
 supervillin
 1054
 0.57
chr18_68086526_68086677 0.38 ENSG00000264059
 .
 57142
 0.13
chr14_50691962_50692201 0.36 SOS2
 son of sevenless homolog 2 (Drosophila)
 5946
 0.22
chr3_42066075_42066314 0.36 ULK4
 unc-51 like kinase 4
 62272
 0.12
chr11_16945886_16946397 0.33 PLEKHA7
 pleckstrin homology domain containing, family A member 7
 43236
 0.13
chr4_114394825_114395109 0.33 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 40031
 0.16
chr6_40925892_40926043 0.32 UNC5CL
 unc-5 homolog C (C. elegans)-like
 76907
 0.08
chr3_58057429_58057580 0.32 FLNB
 filamin B, beta
 6552
 0.27
chr2_24269080_24269320 0.31 ENSG00000222940
 .
 495
 0.58
chr3_183016185_183016744 0.31 B3GNT5
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
 33332
 0.16
chr7_38254764_38254915 0.31 STARD3NL
 STARD3 N-terminal like
 36842
 0.23
chr4_124571341_124571610 0.31 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 250352
 0.02
chr18_805710_806203 0.30 YES1
 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
 6283
 0.16
chr8_70745558_70745875 0.30 SLCO5A1
 solute carrier organic anion transporter family, member 5A1
 91
 0.91
chr3_188599582_188599733 0.29 TPRG1
 tumor protein p63 regulated 1
 65346
 0.14
chr5_121498494_121498645 0.29 CTC-441N14.1
6859
 0.2
chr11_117695326_117695570 0.29 FXYD2
 FXYD domain containing ion transport regulator 2
 11
 0.97
chr17_47440332_47440604 0.29 ZNF652
 zinc finger protein 652
 633
 0.61
chr12_27487334_27487485 0.29 ARNTL2
 aryl hydrocarbon receptor nuclear translocator-like 2
 1421
 0.49
chr18_10169648_10169799 0.29 ENSG00000263630
 .
 164529
 0.03
chr3_81777225_81777376 0.29 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 15480
 0.31
chr4_24606533_24606684 0.28 DHX15
 DEAH (Asp-Glu-Ala-His) box helicase 15
 20435
 0.22
chrX_119689036_119689385 0.28 CUL4B
 cullin 4B
 4588
 0.21
chr8_49322257_49322678 0.28 ENSG00000252710
 .
 101877
 0.08
chr6_74512837_74512988 0.28 RP11-553A21.3
107058
 0.06
chr4_169408783_169408934 0.27 DDX60L
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
 7193
 0.2
chr11_124595039_124595293 0.27 NRGN
 neurogranin (protein kinase C substrate, RC3)
 14576
 0.1
chr17_67498171_67498584 0.27 MAP2K6
 mitogen-activated protein kinase kinase 6
 30
 0.99
chr7_45927984_45928135 0.26 IGFBP1
 insulin-like growth factor binding protein 1
 37
 0.98
chr4_38387684_38387835 0.26 ENSG00000221495
 .
 147525
 0.04
chr15_73927173_73927324 0.26 NPTN
 neuroplastin
 773
 0.72
chr15_64636500_64636651 0.26 ENSG00000252774
 .
 1837
 0.25
chr15_64927439_64927681 0.26 ENSG00000207223
 .
 17527
 0.14
chr6_154640196_154640597 0.25 IPCEF1
 interaction protein for cytohesin exchange factors 1
 10819
 0.3
chr3_192534775_192534926 0.25 FGF12
 fibroblast growth factor 12
 49297
 0.16
chr16_12707264_12707435 0.25 CTD-3037G24.3
2448
 0.33
chr2_208337340_208337637 0.25 CREB1
 cAMP responsive element binding protein 1
 56973
 0.13
chr3_183563309_183563581 0.25 PARL
 presenilin associated, rhomboid-like
 1383
 0.34
chr10_98623724_98623875 0.24 LCOR
 ligand dependent nuclear receptor corepressor
 31062
 0.15
chr3_172312196_172312406 0.24 AC007919.2
 HCG1787166; PRO1163; Uncharacterized protein
 49182
 0.13
chr20_1921396_1921547 0.24 RP4-684O24.5
6421
 0.23
chr4_79489691_79489842 0.24 ANXA3
 annexin A3
 14692
 0.23
chr2_230793147_230793445 0.23 TRIP12
 thyroid hormone receptor interactor 12
 5341
 0.14
chr15_67419351_67419566 0.23 SMAD3
 SMAD family member 3
 983
 0.62
chrX_17581294_17581554 0.23 NHS-AS1
 NHS antisense RNA 1
 5916
 0.25
chr10_63718660_63718935 0.23 ENSG00000221272
 .
 32020
 0.21
chr7_32538317_32538480 0.23 AVL9
 AVL9 homolog (S. cerevisiase)
 3076
 0.29
chr18_13491175_13491326 0.22 RP11-53B2.2
4789
 0.11
chr10_111816096_111816353 0.22 ADD3
 adducin 3 (gamma)
 48502
 0.14
chr2_44518783_44519008 0.22 SLC3A1
 solute carrier family 3 (amino acid transporter heavy chain), member 1
 6261
 0.21
chr5_142554814_142554965 0.22 ARHGAP26-IT1
 ARHGAP26 intronic transcript 1 (non-protein coding)
 17176
 0.24
chr13_114881324_114881475 0.22 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 7104
 0.23
chr15_85937202_85937353 0.22 ENSG00000251891
 .
 4162
 0.24
chr6_108971832_108971983 0.22 FOXO3
 forkhead box O3
 5642
 0.32
chr1_120174414_120175022 0.21 ZNF697
 zinc finger protein 697
 15678
 0.18
chr5_64500241_64500433 0.21 ENSG00000207439
 .
 81141
 0.11
chr5_133387222_133387373 0.21 VDAC1
 voltage-dependent anion channel 1
 46473
 0.14
chr16_81030908_81031149 0.21 CMC2
 C-x(9)-C motif containing 2
 1236
 0.36
chr2_43986548_43986990 0.21 ENSG00000252490
 .
 12720
 0.19
chr12_25648509_25648660 0.21 IFLTD1
 intermediate filament tail domain containing 1
 24311
 0.23
chr12_46867328_46867682 0.21 SLC38A2
 solute carrier family 38, member 2
 100855
 0.08
chr7_22627428_22627634 0.21 AC002480.4
1793
 0.36
chr9_14251173_14251324 0.21 NFIB
 nuclear factor I/B
 56764
 0.15
chrX_129243328_129243479 0.21 ELF4
 E74-like factor 4 (ets domain transcription factor)
 933
 0.6
chr6_132654884_132655035 0.20 MOXD1
 monooxygenase, DBH-like 1
 41245
 0.19
chr18_66372478_66372744 0.20 TMX3
 thioredoxin-related transmembrane protein 3
 9683
 0.22
chr17_71040137_71040288 0.20 SLC39A11
 solute carrier family 39, member 11
 45691
 0.17
chr21_34905841_34905992 0.20 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
 8504
 0.13
chr1_200865216_200865405 0.20 C1orf106
 chromosome 1 open reading frame 106
 1361
 0.42
chr1_68643879_68644030 0.20 ENSG00000221203
 .
 5339
 0.24
chr9_74377924_74378411 0.20 TMEM2
 transmembrane protein 2
 5135
 0.32
chr11_86431921_86432072 0.20 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 48318
 0.17
chr2_169387098_169387498 0.20 ENSG00000265694
 .
 52155
 0.13
chr9_3359879_3360030 0.19 RFX3
 regulatory factor X, 3 (influences HLA class II expression)
 13190
 0.3
chr6_117818099_117818250 0.19 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 14349
 0.17
chr4_76584048_76584199 0.19 ENSG00000201644
 .
 3274
 0.22
chr15_69850121_69850272 0.19 ENSG00000207119
 .
 99708
 0.06
chr3_18177094_18177245 0.19 RP11-158G18.1
273958
 0.02
chr9_22104098_22104249 0.19 CDKN2B-AS1
 CDKN2B antisense RNA 1
 9504
 0.26
chr7_47613250_47613541 0.19 TNS3
 tensin 3
 7834
 0.3
chr2_109203925_109204163 0.19 LIMS1
 LIM and senescent cell antigen-like domains 1
 723
 0.74
chr2_30336938_30337089 0.19 AC016907.3
22186
 0.18
chr10_89142685_89142836 0.18 NUTM2D
 NUT family member 2D
 18014
 0.21
chr15_38549505_38549656 0.18 SPRED1
 sprouty-related, EVH1 domain containing 1
 4198
 0.36
chr2_202270772_202271289 0.18 ENSG00000202008
 .
 17206
 0.15
chr6_16367315_16367466 0.18 ENSG00000265642
 .
 61364
 0.14
chr10_30388154_30388305 0.18 KIAA1462
 KIAA1462
 39776
 0.21
chr1_183812842_183812993 0.18 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
 38627
 0.18
chr3_183266299_183266524 0.18 KLHL6-AS1
 KLHL6 antisense RNA 1
 112
 0.96
chr5_130601387_130601538 0.18 CDC42SE2
 CDC42 small effector 2
 1669
 0.51
chr21_36265275_36265757 0.18 RUNX1
 runt-related transcription factor 1
 3429
 0.38
chr1_20916896_20917047 0.17 CDA
 cytidine deaminase
 1530
 0.37
chr7_135015211_135015362 0.17 STRA8
 stimulated by retinoic acid 8
 98555
 0.06
chr6_130645263_130645558 0.17 SAMD3
 sterile alpha motif domain containing 3
 41160
 0.17
chr10_104103101_104103252 0.17 NFKB2
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
 50691
 0.08
chr3_71634599_71634767 0.17 FOXP1
 forkhead box P1
 1543
 0.42
chr8_121080549_121080727 0.17 COL14A1
 collagen, type XIV, alpha 1
 37178
 0.21
chr7_155601790_155601976 0.17 SHH
 sonic hedgehog
 117
 0.97
chr6_2103859_2104525 0.17 GMDS
 GDP-mannose 4,6-dehydratase
 72033
 0.13
chr4_100007595_100007746 0.17 ADH5
 alcohol dehydrogenase 5 (class III), chi polypeptide
 1303
 0.38
chr3_156252924_156253075 0.17 RP11-305K5.1
10963
 0.22
chr13_27132620_27132950 0.17 WASF3
 WAS protein family, member 3
 898
 0.72
chr9_27094212_27094497 0.17 TEK
 TEK tyrosine kinase, endothelial
 14785
 0.23
chr9_21543413_21543564 0.17 MIR31HG
 MIR31 host gene (non-protein coding)
 16180
 0.15
chr2_233432775_233432926 0.17 EIF4E2
 eukaryotic translation initiation factor 4E family member 2
 5934
 0.11
chrX_39967563_39967714 0.17 BCOR
 BCL6 corepressor
 10982
 0.31
chr6_43730965_43731135 0.17 VEGFA
 vascular endothelial growth factor A
 6900
 0.18
chr7_116228829_116229027 0.17 AC006159.4
17640
 0.18
chr12_65700883_65701407 0.16 MSRB3
 methionine sulfoxide reductase B3
 19510
 0.22
chr9_123960312_123961002 0.16 RAB14
 RAB14, member RAS oncogene family
 3490
 0.19
chr13_20769719_20769870 0.16 GJB2
 gap junction protein, beta 2, 26kDa
 2757
 0.25
chr11_27417260_27417411 0.16 CCDC34
 coiled-coil domain containing 34
 31920
 0.18
chr1_234953186_234953405 0.16 ENSG00000201638
 .
 20425
 0.25
chr15_71346441_71346592 0.16 THSD4
 thrombospondin, type I, domain containing 4
 42775
 0.16
chr5_133939031_133939182 0.16 SAR1B
 SAR1 homolog B (S. cerevisiae)
 9670
 0.17
chr18_452761_452993 0.16 RP11-720L2.2
28461
 0.17
chr6_12343879_12344030 0.16 EDN1
 endothelin 1
 53358
 0.16
chr3_183947384_183948074 0.16 VWA5B2
 von Willebrand factor A domain containing 5B2
 488
 0.65
chr3_152153870_152154021 0.16 ENSG00000201217
 .
 13116
 0.21
chr5_95683555_95683706 0.16 PCSK1
 proprotein convertase subtilisin/kexin type 1
 84234
 0.09
chr6_25311839_25311990 0.16 ENSG00000207286
 .
 24153
 0.15
chr11_111999683_111999892 0.16 IL18
 interleukin 18 (interferon-gamma-inducing factor)
 35010
 0.08
chr2_29339694_29340047 0.16 CLIP4
 CAP-GLY domain containing linker protein family, member 4
 1191
 0.44
chr7_42302451_42302602 0.16 GLI3
 GLI family zinc finger 3
 25868
 0.28
chr14_58748062_58749029 0.16 RP11-349A22.5
5196
 0.12
chr3_185431049_185431200 0.16 C3orf65
 chromosome 3 open reading frame 65
 44
 0.98
chr20_34380481_34380768 0.16 PHF20
 PHD finger protein 20
 20676
 0.13
chr1_33414688_33414839 0.16 RNF19B
 ring finger protein 19B
 15523
 0.12
chr12_54383579_54383730 0.16 HOXC6
 homeobox C6
 754
 0.31
chr7_30836266_30836417 0.16 AC004691.5
6685
 0.2
chr7_110872801_110872972 0.16 ENSG00000238922
 .
 123473
 0.06
chr7_139473808_139474066 0.16 HIPK2
 homeodomain interacting protein kinase 2
 3580
 0.27
chr4_41179011_41179162 0.16 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 37389
 0.15
chr8_17220869_17221020 0.16 MTMR7
 myotubularin related protein 7
 49892
 0.15
chr15_85455088_85455239 0.15 ENSG00000207037
 .
 26590
 0.13
chr8_38029592_38029743 0.15 BAG4
 BCL2-associated athanogene 4
 4439
 0.11
chr6_136760823_136760974 0.15 MAP7
 microtubule-associated protein 7
 27115
 0.21
chr3_48733781_48734150 0.15 IP6K2
 inositol hexakisphosphate kinase 2
 950
 0.42
chr6_46458096_46458346 0.15 RCAN2
 regulator of calcineurin 2
 878
 0.55
chr4_38084935_38085086 0.15 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 37518
 0.21
chr6_169615833_169615984 0.15 XXyac-YX65C7_A.2
2559
 0.38
chr1_8156252_8156403 0.15 ERRFI1
 ERBB receptor feedback inhibitor 1
 69959
 0.1
chr10_71529428_71529579 0.15 COL13A1
 collagen, type XIII, alpha 1
 32141
 0.17
chr5_88717098_88717249 0.15 MEF2C-AS1
 MEF2C antisense RNA 1
 2549
 0.45
chr6_144586213_144586364 0.15 UTRN
 utrophin
 20549
 0.24
chr6_52415213_52415364 0.14 TRAM2
 translocation associated membrane protein 2
 26425
 0.21
chr6_2020825_2021145 0.14 GMDS
 GDP-mannose 4,6-dehydratase
 155240
 0.04
chr3_189743016_189743167 0.14 ENSG00000265045
 .
 88632
 0.08
chr8_129031222_129031516 0.14 ENSG00000222501
 .
 8512
 0.18
chr1_183483781_183483932 0.14 ENSG00000265042
 .
 3957
 0.25
chr19_12722676_12723040 0.14 ZNF791
 zinc finger protein 791
 1090
 0.26
chr10_91092779_91093035 0.14 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
 666
 0.62
chr5_61564187_61564338 0.14 KIF2A
 kinesin heavy chain member 2A
 37727
 0.2
chr8_125266983_125267210 0.14 ENSG00000206724
 .
 5791
 0.28
chr12_79098466_79098617 0.14 SYT1
 synaptotagmin I
 159232
 0.04
chr12_56609980_56610131 0.14 RNF41
 ring finger protein 41
 5430
 0.07
chr10_11602345_11602496 0.14 USP6NL
 USP6 N-terminal like
 13316
 0.25
chr5_134707593_134707838 0.14 H2AFY
 H2A histone family, member Y
 27186
 0.14
chr3_135710315_135710559 0.14 PPP2R3A
 protein phosphatase 2, regulatory subunit B'', alpha
 25851
 0.25
chr17_57746657_57747029 0.14 CLTC
 clathrin, heavy chain (Hc)
 14424
 0.17
chr17_29889114_29889342 0.14 ENSG00000221038
 .
 1685
 0.21
chr4_169361836_169361987 0.14 DDX60L
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
 15299
 0.2
chr10_33995531_33995682 0.14 NRP1
 neuropilin 1
 370416
 0.01
chr17_50225184_50225335 0.14 CA10
 carbonic anhydrase X
 10164
 0.3
chr7_17411629_17411780 0.14 ENSG00000199473
 .
 1246
 0.58
chr8_87496135_87496286 0.14 CPNE3
 copine III
 849
 0.58
chrX_149881301_149881600 0.14 MTMR1
 myotubularin related protein 1
 5699
 0.3
chr12_13054850_13055147 0.14 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 7005
 0.15
chr10_31255665_31255816 0.14 ZNF438
 zinc finger protein 438
 17615
 0.26
chr7_89974617_89974768 0.14 GTPBP10
 GTP-binding protein 10 (putative)
 1287
 0.45
chr11_14375636_14375787 0.14 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 335
 0.93
chr4_123795832_123795983 0.14 RP11-170N16.3
9960
 0.18
chr6_143193207_143193806 0.14 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 35322
 0.21
chr11_113186702_113186853 0.14 TTC12
 tetratricopeptide repeat domain 12
 186
 0.92
chr1_27039284_27039619 0.14 ARID1A
 AT rich interactive domain 1A (SWI-like)
 14748
 0.14
chr20_19795494_19795742 0.13 AL121761.2
 Uncharacterized protein
 56939
 0.12
chr15_71006405_71006665 0.13 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 10921
 0.26
chr3_100112860_100113011 0.13 LNP1
 leukemia NUP98 fusion partner 1
 7102
 0.2
chr3_150936070_150936221 0.13 GPR171
 G protein-coupled receptor 171
 15157
 0.14
chr13_98908338_98908489 0.13 RP11-573N10.1
22509
 0.17
chr18_42313110_42313658 0.13 SETBP1
 SET binding protein 1
 36255
 0.24
chr10_11060742_11061158 0.13 CELF2
 CUGBP, Elav-like family member 2
 844
 0.61
chr9_127428096_127428247 0.13 MIR181A2HG
 MIR181A2 host gene (non-protein coding)
 7425
 0.17
chr4_185709233_185709384 0.13 ACSL1
 acyl-CoA synthetase long-chain family member 1
 14281
 0.18
chr12_889095_889427 0.13 ENSG00000221439
 .
 1038
 0.58
chr2_173952072_173952223 0.13 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
 3200
 0.29
chr18_55480395_55480546 0.13 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 10143
 0.24
chr15_52627311_52627462 0.13 MYO5A
 myosin VA (heavy chain 12, myoxin)
 16193
 0.2
chr3_161027813_161027964 0.13 SPTSSB
 serine palmitoyltransferase, small subunit B
 61401
 0.14
chr14_89019667_89019818 0.13 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 1335
 0.33
chr6_144171782_144171933 0.13 LTV1
 LTV1 homolog (S. cerevisiae)
 7376
 0.24
chr2_98566489_98566757 0.13 ENSG00000238719
 .
 37043
 0.17
chr10_3848729_3848956 0.13 KLF6
 Kruppel-like factor 6
 21369
 0.22
chr10_131555762_131556161 0.13 RP11-109A6.2
56140
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism