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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HOXA1

Z-value: 2.43

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Transcription factors associated with HOXA1

Gene Symbol	Gene ID	Gene Info
HOXA1 Ensembl NCBI GeneCards UniProt	ENSG00000105991.7	homeobox A1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_27135370_27135555	HOXA1	131	0.571442	-0.07	8.6e-01	Click!

Activity of the HOXA1 motif across conditions

Conditions sorted by the z-value of the HOXA1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_13065957_13066108	1.00	IQSEC1	IQ motif and Sec7 domain 1	37496	0.2
chr13_114873900_114874051	0.84	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	320	0.91
chr14_90003505_90003656	0.83	FOXN3-AS2	FOXN3 antisense RNA 2	38980	0.13
chr7_640540_641424	0.76	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	1338	0.36
chr22_34263041_34263192	0.70	LARGE	like-glycosyltransferase	5504	0.29
chr2_3299611_3299762	0.69	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	5550	0.27
chr5_153657458_153657728	0.67	ENSG00000221070	.	62093	0.1
chr1_16492736_16492887	0.64	RP11-276H7.3		7050	0.12
chr19_381111_381262	0.63	THEG	theg spermatid protein	5173	0.15
chr1_11742762_11742913	0.56	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	1566	0.27
chr6_90778869_90779020	0.55	ENSG00000222078	.	67719	0.11
chr15_52019009_52019407	0.55	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2	11110	0.13
chr1_202132763_202133787	0.53	PTPN7	protein tyrosine phosphatase, non-receptor type 7	2559	0.21
chr2_3299852_3300003	0.53	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	5309	0.28
chr10_124180219_124180566	0.50	ENSG00000265442	.	3911	0.21
chr11_95928553_95928846	0.50	ENSG00000266192	.	145903	0.04
chr9_95793129_95793280	0.49	FGD3	FYVE, RhoGEF and PH domain containing 3	15862	0.17
chr15_101741938_101742937	0.49	CHSY1	chondroitin sulfate synthase 1	49700	0.12
chr3_108550085_108550421	0.49	TRAT1	T cell receptor associated transmembrane adaptor 1	8634	0.27
chr4_113437546_113438608	0.48	NEUROG2	neurogenin 2	749	0.58
chr10_30474293_30474444	0.48	ENSG00000200887	.	114234	0.06
chr11_121336559_121337538	0.48	RP11-730K11.1		13326	0.24
chr10_14051000_14051172	0.47	FRMD4A	FERM domain containing 4A	554	0.8
chr21_32738689_32738840	0.47	TIAM1	T-cell lymphoma invasion and metastasis 1	22170	0.27
chr17_65830082_65830233	0.46	BPTF	bromodomain PHD finger transcription factor	7899	0.17
chr6_42326971_42327197	0.45	ENSG00000221252	.	53050	0.13
chr4_122073193_122073446	0.44	TNIP3	TNFAIP3 interacting protein 3	10265	0.23
chr2_121372137_121372546	0.44	ENSG00000201006	.	36508	0.21
chr11_102267624_102267962	0.44	BIRC2	baculoviral IAP repeat containing 2	49793	0.1
chr2_144220343_144220494	0.44	AC096558.1		17932	0.26
chr11_12832428_12832703	0.43	RP11-47J17.3		12649	0.21
chr8_67404169_67404359	0.42	C8orf46	chromosome 8 open reading frame 46	1179	0.48
chr1_54760868_54761170	0.42	RP5-997D24.3		9941	0.19
chr10_81937813_81938167	0.41	ANXA11	annexin A11	5213	0.23
chr14_89713300_89713451	0.41	FOXN3	forkhead box N3	66287	0.12
chr9_120470562_120470843	0.41	ENSG00000201444	.	322	0.9
chr5_150623862_150624013	0.41	GM2A	GM2 ganglioside activator	8516	0.19
chr19_50061032_50061281	0.40	NOSIP	nitric oxide synthase interacting protein	2731	0.1
chr13_32700633_32700915	0.40	FRY	furry homolog (Drosophila)	65773	0.12
chr5_114843276_114843427	0.40	FEM1C	fem-1 homolog c (C. elegans)	37240	0.17
chr5_172905193_172905344	0.40	CTB-33O18.3		101378	0.07
chr8_128520144_128520295	0.39	CASC8	cancer susceptibility candidate 8 (non-protein coding)	25835	0.25
chr9_73021149_73021369	0.39	KLF9	Kruppel-like factor 9	8281	0.28
chr3_66443269_66443807	0.39	ENSG00000241587	.	69259	0.12
chr19_7423428_7423579	0.38	CTB-133G6.1		9655	0.15
chr13_24275410_24275561	0.38	AL139080.1	Uncharacterized protein	46758	0.16
chr1_210014679_210014830	0.38	DIEXF	digestive organ expansion factor homolog (zebrafish)	2604	0.26
chr4_8305331_8305837	0.38	HTRA3	HtrA serine peptidase 3	34080	0.17
chr14_106463441_106463592	0.38	IGHVIII-2-1	immunoglobulin heavy variable (III)-2-1 (pseudogene)	4451	0.06
chr17_37922123_37922274	0.38	IKZF3	IKAROS family zinc finger 3 (Aiolos)	12280	0.12
chr1_100742904_100743055	0.38	ENSG00000207750	.	3818	0.17
chr2_85973319_85973470	0.37	ATOH8	atonal homolog 8 (Drosophila)	7623	0.15
chr4_114608486_114608818	0.37	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	73572	0.13
chr11_60744102_60744253	0.37	CD6	CD6 molecule	4839	0.13
chr10_63831258_63831409	0.37	ARID5B	AT rich interactive domain 5B (MRF1-like)	22363	0.23
chr3_31585090_31585298	0.36	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	10912	0.3
chrX_19619969_19620120	0.36	SH3KBP1	SH3-domain kinase binding protein 1	68436	0.12
chr9_114666357_114666809	0.36	UGCG	UDP-glucose ceramide glucosyltransferase	7537	0.2
chr6_112089861_112090078	0.35	FYN	FYN oncogene related to SRC, FGR, YES	8849	0.28
chr14_69612705_69612857	0.35	ENSG00000206768	.	2111	0.32
chr20_42143574_42144320	0.35	L3MBTL1	l(3)mbt-like 1 (Drosophila)	781	0.59
chr2_227342979_227343130	0.35	ENSG00000263363	.	180455	0.03
chr12_72260725_72261209	0.34	TBC1D15	TBC1 domain family, member 15	27409	0.21
chr3_151896872_151897023	0.34	MBNL1	muscleblind-like splicing regulator 1	88882	0.09
chr13_74438748_74438899	0.34	KLF12	Kruppel-like factor 12	130363	0.06
chr7_127504383_127504534	0.34	SND1	staphylococcal nuclease and tudor domain containing 1	23507	0.25
chr16_89373716_89373867	0.34	AC137932.5		9527	0.13
chr3_106928871_106929022	0.34	ENSG00000220989	.	155083	0.04
chr3_170147264_170147415	0.34	CLDN11	claudin 11	10484	0.26
chr1_240740736_240741022	0.34	RP11-467I20.6		13169	0.2
chr14_89722620_89722771	0.34	FOXN3	forkhead box N3	75607	0.1
chr6_25973027_25973178	0.34	TRIM38	tripartite motif containing 38	9827	0.1
chr17_64342041_64342192	0.33	ENSG00000244044	.	18031	0.2
chr8_6335605_6335756	0.33	RP11-115C21.2		71017	0.1
chr22_37475461_37475625	0.33	RP5-1170K4.7		565	0.62
chr18_20638644_20638795	0.33	ENSG00000223023	.	34160	0.13
chr5_150597516_150598012	0.33	CCDC69	coiled-coil domain containing 69	5942	0.19
chr2_160058942_160059211	0.33	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1	83987	0.1
chr2_30656489_30656640	0.33	ENSG00000221377	.	1250	0.54
chr3_33087403_33087747	0.33	GLB1	galactosidase, beta 1	50709	0.11
chr2_69795993_69796144	0.33	ENSG00000207016	.	48762	0.12
chr12_6178946_6179123	0.33	ENSG00000240533	.	26102	0.19
chr1_203606704_203607193	0.33	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	11020	0.24
chr3_141133468_141133746	0.33	ZBTB38	zinc finger and BTB domain containing 38	11351	0.23
chr14_89794652_89794865	0.33	RP11-356K23.1		21871	0.18
chr7_25891719_25892347	0.33	ENSG00000199085	.	97573	0.09
chr5_177671788_177671939	0.32	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase	12077	0.2
chr7_22707827_22707978	0.32	AC002480.5		6491	0.2
chr3_53069303_53069506	0.32	SFMBT1	Scm-like with four mbt domains 1	9877	0.18
chr2_30477316_30477615	0.32	LBH	limb bud and heart development	22419	0.22
chr12_111873433_111874308	0.32	SH2B3	SH2B adaptor protein 3	1204	0.47
chr11_60890001_60890152	0.32	CD5	CD5 molecule	20095	0.15
chr1_67235783_67235934	0.32	TCTEX1D1	Tctex1 domain containing 1	17715	0.15
chr7_127698825_127699005	0.32	ENSG00000207588	.	22998	0.2
chr22_31848300_31848566	0.32	RP11-247I13.11		1804	0.22
chr21_34611617_34611944	0.32	AP000295.9		7299	0.15
chr17_39114507_39114658	0.32	KRT39	keratin 39	8562	0.08
chr13_30095831_30095982	0.32	MTUS2-AS1	MTUS2 antisense RNA 1	31664	0.21
chr3_32376656_32376948	0.32	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	56361	0.12
chr7_130772886_130773250	0.32	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	165	0.96
chr1_149984676_149984827	0.32	OTUD7B	OTU domain containing 7B	2126	0.26
chr14_98677293_98677464	0.32	ENSG00000222066	.	120709	0.06
chr9_122713224_122713375	0.32	ENSG00000207814	.	294029	0.01
chr18_77265355_77265646	0.32	AC018445.1	Uncharacterized protein	10557	0.27
chr6_112066325_112066681	0.32	FYN	FYN oncogene related to SRC, FGR, YES	13814	0.25
chr1_167409803_167409954	0.32	RP11-104L21.2		18020	0.2
chr17_45358083_45358234	0.32	ENSG00000238419	.	21372	0.12
chr22_43877399_43877550	0.32	EFCAB6-AS1	EFCAB6 antisense RNA 1	34523	0.19
chr6_112098947_112099288	0.31	FYN	FYN oncogene related to SRC, FGR, YES	3166	0.35
chr17_64354339_64354490	0.31	ENSG00000244044	.	5733	0.24
chr11_68023676_68023827	0.31	C11orf24	chromosome 11 open reading frame 24	15664	0.19
chrX_117647162_117647313	0.31	DOCK11	dedicator of cytokinesis 11	17365	0.23
chr10_121013984_121014157	0.31	ENSG00000242853	.	41701	0.11
chr14_98689187_98689819	0.31	ENSG00000222066	.	108584	0.07
chr5_106971420_106971571	0.31	EFNA5	ephrin-A5	34833	0.23
chr11_65876620_65876771	0.31	PACS1	phosphofurin acidic cluster sorting protein 1	8461	0.11
chr12_57487197_57487835	0.31	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	4626	0.11
chr13_31451769_31451920	0.31	MEDAG	mesenteric estrogen-dependent adipogenesis	28484	0.18
chr20_436878_437029	0.31	ENSG00000206797	.	5646	0.17
chr6_24894743_24895047	0.31	FAM65B	family with sequence similarity 65, member B	16300	0.2
chr1_55829518_55829669	0.31	ENSG00000199831	.	12932	0.23
chr7_21474691_21474842	0.31	SP4	Sp4 transcription factor	7105	0.2
chr9_125023522_125023809	0.31	MRRF	mitochondrial ribosome recycling factor	3217	0.16
chr8_23609447_23609604	0.31	ENSG00000216123	.	16633	0.17
chr11_128227126_128227277	0.31	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	148088	0.04
chr2_227817637_227817788	0.31	ENSG00000212391	.	16126	0.23
chr12_3808327_3808592	0.31	ENSG00000222338	.	27034	0.21
chr16_25002951_25003162	0.31	ARHGAP17	Rho GTPase activating protein 17	23596	0.23
chr3_27497662_27497813	0.31	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	508	0.81
chr2_120578129_120578280	0.31	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	60404	0.13
chr16_64663494_64663645	0.31	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	430012	0.01
chr3_152036313_152036556	0.31	MBNL1	muscleblind-like splicing regulator 1	18447	0.2
chr1_225642878_225643029	0.30	RP11-496N12.6		10032	0.2
chr1_1659225_1659440	0.30	CDK11A	cyclin-dependent kinase 11A	3566	0.15
chr14_90009937_90010173	0.30	FOXN3-AS2	FOXN3 antisense RNA 2	32505	0.14
chr5_58426674_58426825	0.30	RP11-266N13.2		91161	0.09
chr1_1593343_1593578	0.30	RP11-345P4.10		2674	0.13
chr7_36085161_36085312	0.30	PP13004		33458	0.18
chr21_45512010_45512161	0.30	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	15086	0.16
chr5_156627474_156627850	0.30	ITK	IL2-inducible T-cell kinase	19825	0.11
chr3_108566267_108566511	0.30	TRAT1	T cell receptor associated transmembrane adaptor 1	24770	0.23
chr20_35557608_35557874	0.30	SAMHD1	SAM domain and HD domain 1	22370	0.17
chr14_99699518_99699950	0.30	AL109767.1		29551	0.18
chr1_92166568_92166719	0.30	ENSG00000239794	.	128988	0.05
chr1_1362586_1362737	0.30	TMEM88B	transmembrane protein 88B	1153	0.23
chr14_91502758_91502909	0.30	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	23645	0.17
chr11_95839885_95840036	0.30	MTMR2	myotubularin related protein 2	182501	0.03
chr7_97958337_97958488	0.29	RP11-307C18.1		6247	0.2
chr16_78803162_78803313	0.29	RP11-319G9.3		127825	0.05
chr5_156976034_156976304	0.29	AC106801.1		16803	0.15
chr11_85761578_85761729	0.29	PICALM	phosphatidylinositol binding clathrin assembly protein	18169	0.21
chr9_81181847_81181998	0.29	PSAT1	phosphoserine aminotransferase 1	269863	0.02
chr12_69034261_69034415	0.29	ENSG00000206650	.	13183	0.19
chr5_543677_544187	0.29	ENSG00000264233	.	7935	0.14
chr10_106739812_106739963	0.29	SORCS3	sortilin-related VPS10 domain containing receptor 3	178799	0.03
chr6_143255793_143256032	0.29	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	10426	0.26
chr10_127859322_127859597	0.29	ENSG00000222740	.	25308	0.25
chr1_21655454_21655664	0.29	ECE1	endothelin converting enzyme 1	16438	0.2
chr12_57458185_57458336	0.29	MYO1A	myosin IA	13301	0.09
chr13_114879199_114879381	0.29	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	4995	0.25
chr6_169958477_169958751	0.29	WDR27	WD repeat domain 27	102174	0.07
chr1_1951998_1952149	0.29	GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	1293	0.33
chr3_112494249_112494410	0.29	ENSG00000242770	.	26996	0.21
chr2_12901157_12901451	0.29	ENSG00000264370	.	23811	0.24
chr12_10874698_10875290	0.29	YBX3	Y box binding protein 3	912	0.56
chr8_355038_355189	0.29	FBXO25	F-box protein 25	1315	0.53
chr20_1644883_1645856	0.29	ENSG00000242348	.	1637	0.31
chr5_134545085_134545236	0.29	C5orf66	chromosome 5 open reading frame 66	128469	0.05
chr17_48104312_48105191	0.29	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	28588	0.11
chr10_3849152_3849639	0.29	KLF6	Kruppel-like factor 6	21922	0.22
chr7_47366368_47366519	0.29	TNS3	tensin 3	46527	0.2
chr15_31630334_31631466	0.29	KLF13	Kruppel-like factor 13	1236	0.62
chr1_240902944_240903095	0.29	RP11-80B9.1		25838	0.19
chr5_140978009_140978248	0.28	DIAPH1	diaphanous-related formin 1	11076	0.11
chr12_45678957_45679108	0.28	ANO6	anoctamin 6	7434	0.32
chr6_41928412_41928563	0.28	CCND3	cyclin D3	18901	0.13
chr1_183028310_183028461	0.28	LAMC1	laminin, gamma 1 (formerly LAMB2)	35790	0.16
chr1_66818663_66819387	0.28	PDE4B	phosphodiesterase 4B, cAMP-specific	1040	0.69
chr15_89203109_89203379	0.28	ISG20	interferon stimulated exonuclease gene 20kDa	21060	0.16
chr10_11360522_11360673	0.28	CELF2-AS1	CELF2 antisense RNA 1	1250	0.61
chr14_62111525_62111676	0.28	RP11-47I22.3	Uncharacterized protein	2538	0.35
chr9_75731604_75731755	0.28	ANXA1	annexin A1	34994	0.2
chr17_9336671_9336893	0.28	AC087501.1		18732	0.19
chr2_19107015_19107166	0.28	NT5C1B	5'-nucleotidase, cytosolic IB	336252	0.01
chr1_35448582_35448833	0.28	ENSG00000241014	.	2207	0.22
chr2_98361004_98361155	0.28	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	10210	0.19
chr2_190126373_190126564	0.28	ENSG00000266817	.	50019	0.15
chr13_99208991_99209442	0.28	STK24	serine/threonine kinase 24	19901	0.19
chrX_152992299_152993172	0.28	ABCD1	ATP-binding cassette, sub-family D (ALD), member 1	1463	0.23
chr6_144627394_144627662	0.28	UTRN	utrophin	14563	0.24
chr3_58102239_58102390	0.28	FLNB	filamin B, beta	33279	0.17
chr3_122807174_122807325	0.28	PDIA5	protein disulfide isomerase family A, member 5	21054	0.22
chr10_134224918_134226015	0.28	PWWP2B	PWWP domain containing 2B	14764	0.17
chr8_61647136_61647287	0.28	CHD7	chromodomain helicase DNA binding protein 7	6713	0.3
chr2_46997189_46997340	0.28	LINC01118	long intergenic non-protein coding RNA 1118	46558	0.11
chr3_57018388_57018539	0.28	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	7060	0.24
chr2_204673809_204673960	0.28	ENSG00000206970	.	27124	0.19
chr11_6424420_6425308	0.28	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	1030	0.44
chr17_30902769_30903098	0.28	RP11-466A19.5		45866	0.1
chr14_68759294_68759585	0.28	ENSG00000243546	.	56183	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.2	1.1	GO:0070670	response to interleukin-4(GO:0070670)
0.2	0.8	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.5	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.4	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.5	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.2	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	2.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.6	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.2	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.3	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.1	0.3	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1	0.4	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	0.2	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.5	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.1	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.1	0.1	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	0.4	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.1	GO:0043931	ossification involved in bone maturation(GO:0043931)
0.1	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.1	0.3	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	0.1	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.1	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.2	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.1	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.1	0.2	GO:0052169	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.2	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.1	GO:0050955	thermoception(GO:0050955)
0.1	0.2	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.1	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.4	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.2	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.2	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0060581	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.3	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.6	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.2	GO:0071548	response to dexamethasone(GO:0071548)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.9	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.6	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.0	GO:0072012	renal system vasculature development(GO:0061437) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012) glomerular mesangium development(GO:0072109)
0.0	0.2	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.0	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.2	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.1	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.3	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0070091	glucagon secretion(GO:0070091)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.5	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.0	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0033087	immature T cell proliferation in thymus(GO:0033080) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0072074	kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075)
0.0	0.5	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.3	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.0	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.1	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.3	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.3	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.2	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.3	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.3	GO:1901224	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	1.1	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.2	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0	0.0	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.4	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0043096	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0090311	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.2	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0010922	positive regulation of phosphatase activity(GO:0010922)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.1	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.0	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0042506	tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.0	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.0	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.1	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0045008	base-excision repair, AP site formation(GO:0006285) depyrimidination(GO:0045008)
0.0	0.0	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.0	GO:0010677	negative regulation of cellular carbohydrate metabolic process(GO:0010677)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.0	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.3	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.0	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.0	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.0	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.0	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.0	GO:0051154	negative regulation of striated muscle cell differentiation(GO:0051154)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.3	GO:0071437	invadopodium(GO:0071437)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.7	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.9	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.7	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.4	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	1.6	GO:0005925	focal adhesion(GO:0005925)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.0	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.0	GO:0070938	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.4	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0005884	actin filament(GO:0005884)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.3	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.6	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.7	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	0.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.1	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	2.0	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	1.5	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	1.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.8	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0016715	dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	1.6	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0017022	myosin binding(GO:0017022)
0.0	0.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.7	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.0	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0043236	laminin binding(GO:0043236)
0.0	0.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.9	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	1.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.1	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.8	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.7	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.0	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.1	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Results for HOXA1

Z-value: 2.43

Motif logo

Transcription factors associated with HOXA1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXA1 motif across conditions

Conditions sorted by the z-value of the HOXA1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: