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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HOXB13

Z-value: 0.77

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Transcription factors associated with HOXB13

Gene Symbol Gene ID Gene Info
ENSG00000159184.7 homeobox B13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_46806332_46806483HOXB131330.9213490.412.7e-01Click!
chr17_46816297_46816448HOXB1398320.1006850.324.0e-01Click!
chr17_46810841_46811006HOXB1343830.1176010.225.7e-01Click!
chr17_46805969_46806120HOXB134960.6462590.186.5e-01Click!
chr17_46811332_46811483HOXB1348670.1139370.117.7e-01Click!

Activity of the HOXB13 motif across conditions

Conditions sorted by the z-value of the HOXB13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_216484078_216484386 0.38 AC012462.1

183256
0.03
chr20_10600399_10600550 0.33 JAG1
jagged 1
42680
0.18
chr2_135814073_135814224 0.33 RAB3GAP1
RAB3 GTPase activating protein subunit 1 (catalytic)
4279
0.2
chr8_122360906_122361134 0.31 ENSG00000221644
.
161888
0.04
chr6_161527421_161527572 0.28 AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
42825
0.18
chr15_60370131_60370351 0.28 FOXB1
forkhead box B1
73820
0.12
chr12_23131728_23131879 0.28 ETNK1
ethanolamine kinase 1
353512
0.01
chr8_27154876_27155049 0.26 TRIM35
tripartite motif containing 35
3310
0.25
chr11_111990686_111990837 0.24 SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
33138
0.08
chr8_19069882_19070033 0.24 SH2D4A
SH2 domain containing 4A
101171
0.08
chr16_50236477_50236828 0.23 ADCY7
adenylate cyclase 7
43396
0.12
chr2_148804260_148804811 0.23 ORC4
origin recognition complex, subunit 4
25388
0.19
chr1_198498527_198498869 0.23 ATP6V1G3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
11106
0.29
chr3_159173828_159173979 0.22 ENSG00000263634
.
173468
0.03
chr10_101692086_101692460 0.21 DNMBP
dynamin binding protein
1520
0.41
chr5_36879254_36879912 0.21 NIPBL
Nipped-B homolog (Drosophila)
2691
0.41
chr5_86422918_86423069 0.21 ENSG00000265919
.
12222
0.22
chr7_17234854_17235017 0.21 AC003075.4

85992
0.1
chr2_176030685_176030836 0.21 ENSG00000215973
.
1677
0.22
chr20_36618887_36619038 0.20 ENSG00000199683
.
15079
0.17
chr17_7653466_7653617 0.20 DNAH2
dynein, axonemal, heavy chain 2
30502
0.08
chr15_59598180_59598331 0.20 RP11-429D19.1

34894
0.11
chr12_25487343_25487617 0.20 ENSG00000201439
.
69882
0.1
chr17_70388485_70388636 0.20 SOX9
SRY (sex determining region Y)-box 9
271399
0.02
chr21_36251212_36251413 0.20 RUNX1
runt-related transcription factor 1
8168
0.31
chr5_38872858_38873009 0.20 OSMR
oncostatin M receptor
26832
0.24
chr19_38700842_38701258 0.20 ENSG00000266428
.
10176
0.1
chr6_10416011_10416162 0.20 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
337
0.82
chr7_56130478_56130743 0.20 SUMF2
sulfatase modifying factor 2
1085
0.32
chr17_15941252_15941403 0.20 NCOR1
nuclear receptor corepressor 1
1453
0.3
chr20_10963665_10963956 0.20 RP11-103J8.1

3513
0.34
chr10_101723594_101723781 0.20 DNMBP
dynamin binding protein
32934
0.15
chr1_199582244_199582395 0.19 ENSG00000263805
.
2089
0.49
chr10_29916759_29916910 0.19 SVIL
supervillin
7067
0.21
chr5_167126219_167126370 0.19 CTB-78F1.2

22074
0.2
chr22_38244115_38244422 0.19 ENSG00000207696
.
487
0.41
chr5_37841386_37841537 0.19 GDNF
glial cell derived neurotrophic factor
1673
0.47
chr10_72593489_72593705 0.19 SGPL1
sphingosine-1-phosphate lyase 1
10657
0.2
chr7_14020149_14020300 0.19 ETV1
ets variant 1
5842
0.29
chr17_69436901_69437052 0.19 ENSG00000222563
.
129667
0.06
chr21_29020378_29020529 0.19 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
681621
0.0
chr11_13964368_13964519 0.19 ENSG00000201856
.
35306
0.23
chr2_227625941_227626092 0.18 IRS1
insulin receptor substrate 1
38459
0.16
chr13_49005626_49005777 0.18 LPAR6
lysophosphatidic acid receptor 6
4658
0.32
chr6_33548164_33548316 0.18 BAK1
BCL2-antagonist/killer 1
221
0.9
chr11_67354003_67354154 0.18 GSTP1
glutathione S-transferase pi 1
2865
0.13
chr2_75847358_75847509 0.18 ENSG00000221638
.
7646
0.14
chr1_12678723_12678924 0.18 DHRS3
dehydrogenase/reductase (SDR family) member 3
1086
0.5
chr14_71956022_71956173 0.18 SIPA1L1
signal-induced proliferation-associated 1 like 1
39945
0.17
chr4_151074226_151074377 0.18 ENSG00000238721
.
56557
0.15
chr1_31889861_31890012 0.18 SERINC2
serine incorporator 2
3276
0.21
chr5_77268268_77268488 0.18 AP3B1
adaptor-related protein complex 3, beta 1 subunit
66596
0.12
chr7_7196352_7196827 0.18 C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
24
0.98
chr3_145902395_145902546 0.18 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
21030
0.2
chr2_40079335_40079486 0.18 SLC8A1-AS1
SLC8A1 antisense RNA 1
65817
0.13
chr2_99342877_99343146 0.17 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
148
0.97
chr9_36194329_36194526 0.17 CLTA
clathrin, light chain A
3467
0.23
chr7_156792904_156793239 0.17 MNX1-AS2
MNX1 antisense RNA 2
5930
0.17
chr1_149816060_149816683 0.17 HIST2H2AA3
histone cluster 2, H2aa3
1893
0.12
chr20_46815691_46815842 0.17 ENSG00000252227
.
51000
0.18
chr22_47212286_47212467 0.17 ENSG00000221672
.
31427
0.17
chr18_53145450_53145601 0.17 ENSG00000264571
.
927
0.57
chrX_24166137_24167088 0.17 ZFX
zinc finger protein, X-linked
1134
0.35
chr5_172328463_172328614 0.17 ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
3682
0.23
chr5_153826475_153827364 0.16 SAP30L
SAP30-like
814
0.51
chr5_179770020_179770171 0.16 GFPT2
glutamine-fructose-6-phosphate transaminase 2
9805
0.21
chr1_43420334_43420485 0.16 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
4091
0.22
chr7_76213485_76213833 0.16 POMZP3
POM121 and ZP3 fusion
33958
0.13
chr3_57958497_57958723 0.16 FLNB
filamin B, beta
35517
0.18
chr14_31641329_31641480 0.16 HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
3857
0.22
chr15_102156555_102156706 0.16 ENSG00000252614
.
31885
0.15
chr2_44798144_44798295 0.16 CAMKMT
calmodulin-lysine N-methyltransferase
198338
0.03
chr12_58781035_58781186 0.16 RP11-362K2.2
Protein LOC100506869
156797
0.04
chr6_110508362_110508550 0.16 CDC40
cell division cycle 40
6832
0.24
chr6_122793405_122793976 0.16 PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
614
0.51
chr17_40949013_40949515 0.15 COA3
cytochrome c oxidase assembly factor 3
1458
0.18
chr2_12618919_12619301 0.15 ENSG00000207183
.
67483
0.14
chr11_33049563_33049714 0.15 TCP11L1
t-complex 11, testis-specific-like 1
11325
0.17
chr12_24753774_24754027 0.15 ENSG00000240481
.
105822
0.08
chr6_140784427_140784578 0.15 ENSG00000221336
.
197348
0.03
chr2_46303608_46303759 0.15 AC017006.2

2284
0.4
chrY_14665326_14665477 0.15 GYG2P1
glycogenin 2 pseudogene 1
133280
0.05
chr6_38229324_38229475 0.15 ENSG00000200706
.
54349
0.16
chr12_68374810_68375098 0.15 IFNG-AS1
IFNG antisense RNA 1
8271
0.31
chr14_52077289_52077440 0.15 ENSG00000251771
.
5746
0.23
chr3_127454839_127454990 0.15 MGLL
monoglyceride lipase
286
0.93
chr22_38898988_38899381 0.15 DDX17
DEAD (Asp-Glu-Ala-Asp) box helicase 17
3133
0.2
chr12_26899168_26899462 0.15 ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
86399
0.09
chr5_133328742_133328893 0.14 VDAC1
voltage-dependent anion channel 1
11509
0.22
chr4_169691508_169691659 0.14 PALLD
palladin, cytoskeletal associated protein
58273
0.12
chr5_107009300_107009451 0.14 EFNA5
ephrin-A5
2779
0.38
chr5_136483987_136484138 0.14 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
165165
0.04
chr1_64449955_64450106 0.14 ENSG00000207190
.
44642
0.17
chr6_126362121_126362442 0.14 TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
34293
0.18
chr17_64345059_64345333 0.14 ENSG00000244044
.
14951
0.2
chr4_100368387_100368679 0.14 ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
11639
0.22
chr6_128833498_128833649 0.14 RP1-86D1.4

7303
0.17
chr2_105460725_105461021 0.14 LINC01158
long intergenic non-protein coding RNA 1158
7038
0.15
chr16_84766620_84766890 0.14 USP10
ubiquitin specific peptidase 10
33109
0.16
chr5_141707709_141707943 0.14 AC005592.2

2963
0.28
chr3_65982631_65982782 0.14 ENSG00000202071
.
6909
0.21
chr10_73600697_73600848 0.14 ENSG00000238446
.
3779
0.22
chr5_108992233_108992456 0.14 ENSG00000266090
.
28937
0.18
chr12_79960162_79960313 0.14 PAWR
PRKC, apoptosis, WT1, regulator
30077
0.18
chr5_150160797_150161161 0.14 AC010441.1

3112
0.19
chr3_59761256_59761407 0.14 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
196252
0.03
chr2_128615982_128616171 0.14 POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
345
0.84
chr5_83222299_83222450 0.14 ENSG00000216125
.
47331
0.18
chr1_174131198_174131349 0.14 RABGAP1L
RAB GTPase activating protein 1-like
2545
0.33
chr3_42861494_42861645 0.14 ACKR2
atypical chemokine receptor 2
458
0.72
chr6_126305019_126305170 0.14 TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
2482
0.26
chr6_80853031_80853182 0.14 BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
36723
0.23
chr18_55853503_55853654 0.14 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
9044
0.23
chr9_116641852_116642003 0.14 ZNF618
zinc finger protein 618
3297
0.35
chr4_82390108_82390350 0.13 RASGEF1B
RasGEF domain family, member 1B
2161
0.47
chr12_80950525_80950676 0.13 RP11-272K23.3

36880
0.19
chr21_39992446_39992744 0.13 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
35726
0.23
chrX_44730783_44731431 0.13 KDM6A
lysine (K)-specific demethylase 6A
1650
0.39
chr4_123461472_123461766 0.13 IL21-AS1
IL21 antisense RNA 1
78519
0.09
chr18_19971465_19971616 0.13 CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
23290
0.24
chr14_69535729_69536049 0.13 ENSG00000206768
.
74781
0.09
chr6_26049516_26049667 0.13 HIST1H3C
histone cluster 1, H3c
3952
0.08
chr13_51104174_51104472 0.13 ENSG00000221198
.
166950
0.04
chr8_87535059_87535465 0.13 CPNE3
copine III
6029
0.21
chr2_233453893_233454044 0.13 AC073254.1

2564
0.17
chr13_76867098_76867386 0.13 ENSG00000243274
.
158175
0.04
chr12_106630836_106630987 0.13 RP11-651L5.2

9823
0.18
chr7_151434053_151434204 0.13 PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
728
0.74
chr11_130036128_130036279 0.13 ST14
suppression of tumorigenicity 14 (colon carcinoma)
6746
0.27
chr17_60074998_60075962 0.13 ENSG00000242398
.
7868
0.17
chr14_103859829_103860122 0.13 MARK3
MAP/microtubule affinity-regulating kinase 3
7399
0.18
chr2_70142925_70143800 0.13 MXD1
MAX dimerization protein 1
1042
0.4
chr6_27833560_27833860 0.13 HIST1H2AL
histone cluster 1, H2al
676
0.39
chr13_74271902_74272053 0.12 KLF12
Kruppel-like factor 12
297209
0.01
chr12_10876643_10876807 0.12 YBX3
Y box binding protein 3
814
0.61
chr1_198143089_198143887 0.12 NEK7
NIMA-related kinase 7
17237
0.29
chr7_123387049_123387200 0.12 WASL
Wiskott-Aldrich syndrome-like
1997
0.27
chr6_14128901_14129195 0.12 CD83
CD83 molecule
11176
0.25
chr2_216529775_216530114 0.12 ENSG00000212055
.
213698
0.02
chr5_83018281_83018896 0.12 HAPLN1
hyaluronan and proteoglycan link protein 1
1156
0.52
chr6_43894280_43894431 0.12 C6orf223
chromosome 6 open reading frame 223
73962
0.08
chr3_12879901_12880174 0.12 ENSG00000207496
.
1912
0.22
chr10_35626541_35627695 0.12 CCNY
cyclin Y
1316
0.4
chr4_169752762_169753076 0.12 PALLD
palladin, cytoskeletal associated protein
237
0.89
chr7_156739962_156740113 0.12 NOM1
nucleolar protein with MIF4G domain 1
2380
0.29
chr2_65453360_65453632 0.12 ACTR2
ARP2 actin-related protein 2 homolog (yeast)
1391
0.5
chr3_194391812_194392295 0.12 LSG1
large 60S subunit nuclear export GTPase 1
1153
0.38
chr19_8383856_8384007 0.12 NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
2349
0.15
chr11_46535797_46536138 0.12 ENSG00000265014
.
62528
0.09
chr12_76414837_76415483 0.12 RP11-290L1.3

9114
0.19
chr3_177624333_177624484 0.12 ENSG00000199858
.
101159
0.09
chr2_86408072_86408223 0.12 IMMT
inner membrane protein, mitochondrial
7262
0.12
chr5_57557351_57557502 0.12 ENSG00000238899
.
191411
0.03
chr2_102681351_102681502 0.12 IL1R1
interleukin 1 receptor, type I
422
0.88
chr1_2205577_2205728 0.12 SKI
v-ski avian sarcoma viral oncogene homolog
45518
0.08
chr16_9189167_9189953 0.12 C16orf72
chromosome 16 open reading frame 72
4055
0.18
chr20_37485148_37485299 0.12 ENSG00000240474
.
16190
0.19
chr9_34252490_34252641 0.12 ENSG00000222426
.
30103
0.1
chrX_13007464_13007615 0.12 TMSB4X
thymosin beta 4, X-linked
13762
0.22
chr3_111793003_111793154 0.12 C3orf52
chromosome 3 open reading frame 52
12104
0.16
chr1_151592190_151592613 0.11 RP11-404E16.1

6562
0.11
chr1_83030740_83030891 0.11 LPHN2
latrophilin 2
585242
0.0
chr12_22387753_22387904 0.11 ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
14152
0.25
chr5_14810981_14811591 0.11 ENSG00000264792
.
14835
0.24
chr3_156510400_156510551 0.11 LEKR1
leucine, glutamate and lysine rich 1
33614
0.21
chr11_124542402_124542553 0.11 SPA17
sperm autoantigenic protein 17
1217
0.28
chr17_27897968_27898119 0.11 TP53I13
tumor protein p53 inducible protein 13
1405
0.19
chr10_131750921_131751072 0.11 EBF3
early B-cell factor 3
11109
0.3
chr15_52753628_52753923 0.11 MYO5A
myosin VA (heavy chain 12, myoxin)
25908
0.21
chr4_119608098_119608296 0.11 METTL14
methyltransferase like 14
1627
0.48
chr7_104918256_104918407 0.11 SRPK2
SRSF protein kinase 2
8869
0.22
chr1_43151129_43151715 0.11 YBX1
Y box binding protein 1
2764
0.23
chrX_22318328_22318479 0.11 ZNF645
zinc finger protein 645
27338
0.25
chr2_205995260_205995411 0.11 NRP2
neuropilin 2
551889
0.0
chr11_122603673_122604064 0.11 ENSG00000239079
.
6849
0.26
chr4_151231130_151231281 0.11 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
7342
0.31
chr1_225843948_225844099 0.11 ENAH
enabled homolog (Drosophila)
3179
0.27
chr4_54975045_54975230 0.11 ENSG00000221219
.
5314
0.18
chr13_109783595_109783805 0.11 MYO16-AS2
MYO16 antisense RNA 2
29433
0.24
chr1_229415776_229415934 0.11 RAB4A
RAB4A, member RAS oncogene family
8976
0.15
chr5_109029475_109029626 0.11 MAN2A1
mannosidase, alpha, class 2A, member 1
4483
0.22
chr5_57484730_57484881 0.11 ENSG00000238899
.
118790
0.06
chr20_43590444_43590650 0.11 TOMM34
translocase of outer mitochondrial membrane 34
1420
0.33
chr11_45870605_45870756 0.11 CRY2
cryptochrome 2 (photolyase-like)
1723
0.3
chr2_134900167_134900318 0.11 ENSG00000263813
.
15546
0.23
chr11_57539746_57540045 0.11 CTNND1
catenin (cadherin-associated protein), delta 1
8570
0.15
chr4_129733836_129734549 0.11 JADE1
jade family PHD finger 1
1193
0.62
chr2_203498647_203499096 0.11 FAM117B
family with sequence similarity 117, member B
1030
0.67
chr20_48470048_48470199 0.11 ENSG00000252123
.
25594
0.13
chr10_23634401_23634613 0.11 C10orf67
chromosome 10 open reading frame 67
733
0.58
chr9_89696027_89696178 0.11 C9orf170
chromosome 9 open reading frame 170
67457
0.13
chr3_48858285_48858436 0.11 PRKAR2A-AS1
PRKAR2A antisense RNA 1
26645
0.12
chr1_115866355_115866506 0.11 NGF
nerve growth factor (beta polypeptide)
14427
0.24
chr11_62439776_62440015 0.11 C11orf48
chromosome 11 open reading frame 48
168
0.78
chr15_67492948_67493403 0.11 SMAD3
SMAD family member 3
16062
0.2
chr13_32663117_32663268 0.11 FRY
furry homolog (Drosophila)
28191
0.21
chr1_180600327_180600734 0.11 XPR1
xenotropic and polytropic retrovirus receptor 1
610
0.8
chr12_72240351_72240502 0.11 TBC1D15
TBC1 domain family, member 15
6868
0.27
chr3_63954596_63954752 0.11 ATXN7
ataxin 7
1254
0.4
chr12_24714032_24714515 0.11 ENSG00000240481
.
145449
0.05

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity