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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HOXB5

Z-value: 1.38

Motif logo

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Transcription factors associated with HOXB5

Gene Symbol Gene ID Gene Info
HOXB5
ENSG00000120075.5 homeobox B5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_46670430_46670597HOXB58100.2635840.353.5e-01Click!
chr17_46670674_46671049HOXB54620.525865-0.215.9e-01Click!
chr17_46671392_46671683HOXB52140.8051060.127.6e-01Click!

Activity of the HOXB5 motif across conditions

Conditions sorted by the z-value of the HOXB5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_13457216_13457610 0.77 NUP210
 nucleoporin 210kDa
 4396
 0.28
chr16_50720309_50720716 0.57 SNX20
 sorting nexin 20
 5248
 0.13
chr2_143883953_143884119 0.55 ARHGAP15
 Rho GTPase activating protein 15
 2847
 0.35
chr11_85903802_85903953 0.55 ENSG00000200877
 .
 39608
 0.15
chr2_149304182_149304365 0.52 MBD5
 methyl-CpG binding domain protein 5
 77979
 0.11
chr1_160544322_160544473 0.49 CD84
 CD84 molecule
 4866
 0.16
chr14_22957256_22957407 0.48 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 1160
 0.31
chr16_53544923_53545074 0.46 AKTIP
 AKT interacting protein
 6675
 0.23
chr6_108278816_108278967 0.46 RP1-191J18.66
274
 0.56
chr5_150623515_150623785 0.46 GM2A
 GM2 ganglioside activator
 8803
 0.19
chr18_56324663_56325184 0.46 MALT1
 mucosa associated lymphoid tissue lymphoma translocation gene 1
 13695
 0.14
chr2_103034112_103034476 0.46 IL18RAP
 interleukin 18 receptor accessory protein
 855
 0.53
chr5_175456482_175456633 0.45 THOC3
 THO complex 3
 5126
 0.16
chr9_20997618_20997943 0.44 PTPLAD2
 protein tyrosine phosphatase-like A domain containing 2
 33828
 0.16
chr14_52374460_52374611 0.44 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
 5295
 0.19
chr22_37620188_37620478 0.43 SSTR3
 somatostatin receptor 3
 11971
 0.13
chr7_151046492_151046873 0.43 NUB1
 negative regulator of ubiquitin-like proteins 1
 4251
 0.18
chr7_130784590_130784741 0.43 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 7124
 0.22
chr1_32127594_32127745 0.42 COL16A1
 collagen, type XVI, alpha 1
 4013
 0.15
chr17_7238561_7238964 0.42 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 1086
 0.22
chr17_33612463_33612749 0.42 SLFN5
 schlafen family member 5
 42498
 0.11
chr17_66346042_66346193 0.41 ARSG
 arylsulfatase G
 58458
 0.1
chr10_127515808_127515959 0.41 BCCIP
 BRCA2 and CDKN1A interacting protein
 3768
 0.14
chr17_4404014_4404514 0.40 AC118754.4
1295
 0.31
chr7_8056755_8056906 0.40 AC006042.7
47296
 0.13
chr6_167534795_167535192 0.40 CCR6
 chemokine (C-C motif) receptor 6
 1264
 0.46
chr16_28212646_28212858 0.40 XPO6
 exportin 6
 10045
 0.17
chr20_48843581_48843732 0.39 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 36280
 0.16
chr7_12770799_12771102 0.38 ENSG00000199470
 .
 30436
 0.2
chr9_132629831_132629982 0.38 USP20
 ubiquitin specific peptidase 20
 32149
 0.12
chr13_33296824_33296975 0.38 PDS5B
 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
 35408
 0.19
chr6_110500985_110501198 0.38 WASF1
 WAS protein family, member 1
 35
 0.77
chr6_106095597_106095936 0.38 PREP
 prolyl endopeptidase
 244807
 0.02
chr12_83108332_83108483 0.37 TMTC2
 transmembrane and tetratricopeptide repeat containing 2
 27627
 0.27
chr5_95161582_95161941 0.37 GLRX
 glutaredoxin (thioltransferase)
 3052
 0.2
chrX_118781177_118781328 0.37 ENSG00000211578
 .
 441
 0.81
chr22_23486285_23486436 0.37 RTDR1
 rhabdoid tumor deletion region gene 1
 848
 0.39
chr2_43355583_43355909 0.37 ENSG00000207087
 .
 37114
 0.2
chr7_102069746_102070456 0.37 ORAI2
 ORAI calcium release-activated calcium modulator 2
 3452
 0.11
chr5_75709889_75710222 0.37 IQGAP2
 IQ motif containing GTPase activating protein 2
 9806
 0.28
chr1_157963439_157963975 0.37 KIRREL
 kin of IRRE like (Drosophila)
 272
 0.93
chr2_153031608_153031759 0.36 STAM2
 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
 823
 0.72
chr14_24021277_24021443 0.36 ZFHX2
 zinc finger homeobox 2
 502
 0.64
chr18_56382154_56382522 0.36 RP11-126O1.4
37492
 0.12
chr2_99068894_99069462 0.36 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 7765
 0.25
chr15_81587451_81588017 0.35 IL16
 interleukin 16
 1520
 0.42
chr13_100012790_100013013 0.35 ENSG00000207719
 .
 4516
 0.25
chr12_6892610_6892761 0.35 ENSG00000244532
 .
 642
 0.46
chrX_64945443_64945693 0.35 MSN
 moesin
 58031
 0.16
chr6_143861183_143861457 0.35 PHACTR2
 phosphatase and actin regulator 2
 3338
 0.21
chr8_129694153_129694304 0.35 ENSG00000221351
 .
 137812
 0.05
chrX_101857495_101857646 0.35 ARMCX5
 armadillo repeat containing, X-linked 5
 1505
 0.37
chrX_70324332_70324541 0.35 CXorf65
 chromosome X open reading frame 65
 2019
 0.18
chr17_72752966_72753168 0.35 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 5075
 0.11
chr15_91081084_91081235 0.34 CRTC3
 CREB regulated transcription coactivator 3
 7859
 0.21
chr1_160537117_160537336 0.34 CD84
 CD84 molecule
 12037
 0.14
chr1_202597717_202597987 0.34 SYT2
 synaptotagmin II
 14729
 0.19
chr14_93105749_93105900 0.34 RIN3
 Ras and Rab interactor 3
 13022
 0.27
chr11_44630544_44630700 0.34 RP11-58K22.4
971
 0.55
chr3_47025143_47025429 0.34 CCDC12
 coiled-coil domain containing 12
 1814
 0.32
chr13_52393868_52394096 0.34 RP11-327P2.5
15549
 0.18
chr6_52262511_52262820 0.34 EFHC1
 EF-hand domain (C-terminal) containing 1
 22441
 0.2
chr6_53199538_53199739 0.34 ELOVL5
 ELOVL fatty acid elongase 5
 13949
 0.2
chr5_39189552_39189909 0.34 FYB
 FYN binding protein
 13399
 0.27
chr6_45563562_45563713 0.33 ENSG00000252738
 .
 50204
 0.18
chr5_1314270_1314421 0.33 ENSG00000263670
 .
 4853
 0.19
chr1_158255508_158255815 0.33 CD1C
 CD1c molecule
 3915
 0.22
chr1_226863115_226863281 0.33 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 430
 0.85
chr5_176172799_176173168 0.33 UNC5A
 unc-5 homolog A (C. elegans)
 64495
 0.09
chr16_88759405_88759694 0.33 RP5-1142A6.5
3360
 0.09
chr19_41813754_41814061 0.33 CCDC97
 coiled-coil domain containing 97
 2187
 0.19
chr2_71562064_71562215 0.33 ZNF638
 zinc finger protein 638
 3227
 0.29
chr14_61977064_61977273 0.33 RP11-47I22.4
18678
 0.19
chrX_135702154_135702305 0.33 ENSG00000233093
 .
 19473
 0.14
chr4_109031937_109032201 0.32 LEF1
 lymphoid enhancer-binding factor 1
 55388
 0.13
chr3_53063759_53063910 0.32 SFMBT1
 Scm-like with four mbt domains 1
 15447
 0.17
chr1_36678399_36678593 0.32 THRAP3
 thyroid hormone receptor associated protein 3
 11521
 0.15
chr15_63783402_63783553 0.32 USP3
 ubiquitin specific peptidase 3
 13316
 0.23
chr5_66483406_66483586 0.32 CD180
 CD180 molecule
 9131
 0.28
chr10_115967390_115967541 0.32 TDRD1
 tudor domain containing 1
 28116
 0.14
chr1_184944092_184944619 0.32 FAM129A
 family with sequence similarity 129, member A
 673
 0.75
chr1_89486291_89486615 0.32 ENSG00000202385
 .
 405
 0.78
chrX_123353114_123353327 0.31 ENSG00000252693
 .
 21627
 0.25
chr17_15905285_15905436 0.31 ZSWIM7
 zinc finger, SWIM-type containing 7
 2354
 0.22
chr13_99916204_99916355 0.31 GPR18
 G protein-coupled receptor 18
 2281
 0.31
chr16_30379858_30380009 0.31 TBC1D10B
 TBC1 domain family, member 10B
 1652
 0.17
chr6_112311050_112311201 0.31 WISP3
 WNT1 inducible signaling pathway protein 3
 64150
 0.11
chr15_45024051_45024202 0.31 TRIM69
 tripartite motif containing 69
 2940
 0.21
chr11_128382093_128382244 0.31 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 6879
 0.25
chr12_58027267_58027418 0.31 B4GALNT1
 beta-1,4-N-acetyl-galactosaminyl transferase 1
 204
 0.86
chr3_45430424_45430606 0.31 LARS2
 leucyl-tRNA synthetase 2, mitochondrial
 404
 0.9
chr1_38316786_38316995 0.31 MTF1
 metal-regulatory transcription factor 1
 8402
 0.1
chr6_155070964_155071137 0.31 SCAF8
 SR-related CTD-associated factor 8
 16500
 0.23
chr1_158984706_158984928 0.31 IFI16
 interferon, gamma-inducible protein 16
 346
 0.89
chr1_28453002_28453170 0.31 ENSG00000253005
 .
 16266
 0.12
chr3_15597201_15597352 0.31 COLQ
 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
 34018
 0.12
chr11_123552269_123552420 0.31 SCN3B
 sodium channel, voltage-gated, type III, beta subunit
 26392
 0.14
chr17_8858889_8859261 0.31 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 9949
 0.24
chr6_43299390_43299611 0.30 ZNF318
 zinc finger protein 318
 11074
 0.14
chr17_72984009_72984428 0.30 CDR2L
 cerebellar degeneration-related protein 2-like
 491
 0.63
chr5_66809962_66810113 0.30 ENSG00000222939
 .
 49601
 0.2
chr3_10280429_10280763 0.30 TATDN2
 TatD DNase domain containing 2
 9111
 0.13
chr7_142378423_142378715 0.30 MTRNR2L6
 MT-RNR2-like 6
 4465
 0.28
chr5_142737307_142737458 0.30 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
 43035
 0.2
chr21_34606770_34607111 0.30 IFNAR2
 interferon (alpha, beta and omega) receptor 2
 4226
 0.17
chr6_118002568_118002719 0.30 NUS1
 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
 5978
 0.3
chr10_13148496_13148807 0.30 OPTN
 optineurin
 6426
 0.2
chr17_62010060_62010211 0.30 CD79B
 CD79b molecule, immunoglobulin-associated beta
 421
 0.74
chr8_146018396_146018558 0.30 RPL8
 ribosomal protein L8
 505
 0.65
chr22_17570345_17570505 0.30 IL17RA
 interleukin 17 receptor A
 4576
 0.19
chr11_117884308_117884597 0.29 IL10RA
 interleukin 10 receptor, alpha
 27343
 0.14
chr6_34152409_34152560 0.29 GRM4
 glutamate receptor, metabotropic 4
 29085
 0.17
chrX_118789581_118789748 0.29 ENSG00000211578
 .
 8853
 0.17
chr3_130613754_130614033 0.29 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
 408
 0.84
chr8_2077178_2077450 0.29 MYOM2
 myomesin 2
 84130
 0.11
chr13_99931416_99931591 0.29 GPR18
 G protein-coupled receptor 18
 17505
 0.18
chr1_9477618_9477769 0.29 ENSG00000252956
 .
 20144
 0.21
chr1_158218506_158218726 0.29 CD1A
 CD1a molecule
 5311
 0.22
chr18_43268903_43269487 0.29 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 23088
 0.16
chr15_86249746_86250319 0.29 RP11-815J21.1
5692
 0.13
chr9_140195094_140195255 0.29 NRARP
 NOTCH-regulated ankyrin repeat protein
 1529
 0.21
chr1_1712444_1712922 0.29 NADK
 NAD kinase
 1175
 0.4
chr13_74591900_74592051 0.28 KLF12
 Kruppel-like factor 12
 22789
 0.29
chr3_186776851_186777002 0.28 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 15395
 0.23
chr5_169744528_169744722 0.28 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 19394
 0.19
chr12_56733182_56733440 0.28 IL23A
 interleukin 23, alpha subunit p19
 648
 0.46
chrX_100662156_100662307 0.28 GLA
 galactosidase, alpha
 682
 0.45
chrX_65225891_65226383 0.28 RP6-159A1.3
6544
 0.22
chr4_89199715_89199866 0.28 ENSG00000200469
 .
 3330
 0.19
chr12_113621285_113621493 0.28 DDX54
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
 218
 0.86
chr4_103546216_103546367 0.28 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
 47270
 0.15
chr1_110331899_110332050 0.28 EPS8L3
 EPS8-like 3
 25325
 0.13
chr15_30468678_30468972 0.27 ENSG00000221785
 .
 31745
 0.11
chr20_48329492_48329643 0.27 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 848
 0.61
chr2_27071961_27072112 0.27 DPYSL5
 dihydropyrimidinase-like 5
 660
 0.72
chr15_86325217_86325368 0.27 ENSG00000221634
 .
 11483
 0.11
chr3_17621324_17621533 0.27 TBC1D5
 TBC1 domain family, member 5
 43980
 0.2
chr9_15300217_15300592 0.27 TTC39B
 tetratricopeptide repeat domain 39B
 6803
 0.25
chr1_36634160_36634311 0.27 MAP7D1
 MAP7 domain containing 1
 8083
 0.14
chr20_3725478_3725931 0.27 HSPA12B
 heat shock 70kD protein 12B
 12346
 0.12
chr20_62579033_62579428 0.27 UCKL1
 uridine-cytidine kinase 1-like 1
 3249
 0.09
chrY_7188749_7188900 0.27 ENSG00000252633
 .
 3812
 0.24
chr18_21514931_21515082 0.27 LAMA3
 laminin, alpha 3
 6803
 0.22
chr11_113948126_113948329 0.27 ENSG00000221112
 .
 9424
 0.21
chr1_156457116_156457326 0.27 MEF2D
 myocyte enhancer factor 2D
 3170
 0.16
chr1_182599288_182599608 0.27 RGS16
 regulator of G-protein signaling 16
 25905
 0.17
chrX_135747491_135747642 0.27 CD40LG
 CD40 ligand
 17180
 0.17
chr9_316050_316201 0.26 DOCK8
 dedicator of cytokinesis 8
 43055
 0.14
chr15_32654105_32654382 0.26 ENSG00000221444
 .
 31430
 0.1
chr11_121521536_121521776 0.26 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 60528
 0.16
chr18_74176432_74176583 0.26 ZNF516
 zinc finger protein 516
 26228
 0.16
chr10_17548800_17549076 0.26 ST8SIA6
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
 52609
 0.13
chr16_3122157_3122311 0.26 ENSG00000252561
 .
 2710
 0.09
chr14_68951873_68952122 0.26 RAD51B
 RAD51 paralog B
 73770
 0.11
chr2_198075933_198076206 0.26 ANKRD44
 ankyrin repeat domain 44
 13307
 0.2
chr12_64978366_64978542 0.26 ENSG00000223294
 .
 9009
 0.14
chr12_58175242_58176026 0.26 TSFM
 Ts translation elongation factor, mitochondrial
 738
 0.36
chr3_31592528_31592679 0.26 STT3B
 STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
 18321
 0.28
chr8_129556248_129556417 0.26 ENSG00000221351
 .
 275708
 0.01
chr1_154312907_154313058 0.26 ENSG00000238365
 .
 1763
 0.21
chr15_70849476_70849729 0.26 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 145018
 0.05
chr17_26876127_26876878 0.26 UNC119
 unc-119 homolog (C. elegans)
 85
 0.93
chr1_248905757_248905908 0.26 LYPD8
 LY6/PLAUR domain containing 8
 2682
 0.28
chr14_100568921_100569190 0.26 EVL
 Enah/Vasp-like
 5771
 0.14
chr15_92401400_92401706 0.26 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 4202
 0.3
chr2_198294526_198294745 0.26 SF3B1
 splicing factor 3b, subunit 1, 155kDa
 5116
 0.15
chr3_15319690_15320104 0.26 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 2345
 0.23
chr3_122295994_122296195 0.26 PARP15
 poly (ADP-ribose) polymerase family, member 15
 355
 0.86
chr1_55070670_55070938 0.26 FAM151A
 family with sequence similarity 151, member A
 18425
 0.14
chr2_69006771_69007110 0.25 ARHGAP25
 Rho GTPase activating protein 25
 4868
 0.27
chr10_17703984_17704256 0.25 ENSG00000251959
 .
 17067
 0.14
chr2_65172918_65173113 0.25 ENSG00000238696
 .
 37195
 0.12
chr1_76751688_76751938 0.25 ST6GALNAC3
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
 211409
 0.02
chr10_97415695_97415896 0.25 ALDH18A1
 aldehyde dehydrogenase 18 family, member A1
 668
 0.74
chr11_118109252_118109403 0.25 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 13518
 0.13
chr7_150267291_150267625 0.25 GIMAP4
 GTPase, IMAP family member 4
 2934
 0.27
chr3_186657505_186657656 0.25 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 8439
 0.21
chr7_77317684_77317835 0.25 RSBN1L
 round spermatid basic protein 1-like
 8001
 0.26
chr2_99312607_99313038 0.25 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 30337
 0.18
chr8_126661069_126661220 0.25 ENSG00000266452
 .
 204337
 0.03
chr18_60881389_60881563 0.25 ENSG00000238988
 .
 19578
 0.21
chr15_75642153_75642345 0.25 NEIL1
 nei endonuclease VIII-like 1 (E. coli)
 1509
 0.26
chr11_121331911_121332238 0.25 RP11-730K11.1
8352
 0.25
chr1_156183961_156184321 0.25 PMF1-BGLAP
 PMF1-BGLAP readthrough
 1341
 0.22
chr1_111436803_111436998 0.24 CD53
 CD53 molecule
 21124
 0.16
chr9_6422321_6422472 0.24 UHRF2
 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
 1365
 0.45
chr19_30172794_30172945 0.24 PLEKHF1
 pleckstrin homology domain containing, family F (with FYVE domain) member 1
 15088
 0.21
chrX_19795655_19795879 0.24 SH3KBP1
 SH3-domain kinase binding protein 1
 22102
 0.26
chr1_111180656_111180873 0.24 KCNA2
 potassium voltage-gated channel, shaker-related subfamily, member 2
 6668
 0.19
chr3_42390480_42390631 0.24 LYZL4
 lysozyme-like 4
 61495
 0.1
chr9_130532441_130532713 0.24 SH2D3C
 SH2 domain containing 3C
 1140
 0.29
chr8_126661631_126661782 0.24 ENSG00000266452
 .
 204899
 0.02
chr8_95229930_95230081 0.24 CDH17
 cadherin 17, LI cadherin (liver-intestine)
 474
 0.86
chr6_53202509_53202860 0.24 ELOVL5
 ELOVL fatty acid elongase 5
 10903
 0.21
chr3_133300803_133300954 0.24 CDV3
 CDV3 homolog (mouse)
 7386
 0.21
chr6_125390047_125390198 0.24 RNF217
 ring finger protein 217
 20764
 0.24
chr3_50657101_50657507 0.24 MAPKAPK3
 mitogen-activated protein kinase-activated protein kinase 3
 2483
 0.23
chr20_30973001_30973152 0.24 ASXL1
 additional sex combs like 1 (Drosophila)
 25526
 0.17
chr2_198192116_198192267 0.24 AC010746.3
16074
 0.15
chr14_67983023_67983217 0.23 TMEM229B
 transmembrane protein 229B
 932
 0.54

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0052167 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0031342 negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of cell killing(GO:0031342)
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.0 0.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.0 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.3 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.0 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0002883 hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883) positive regulation of hypersensitivity(GO:0002885)
0.0 0.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001940 male pronucleus(GO:0001940)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.2 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases