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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HOXB8

Z-value: 1.30

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Transcription factors associated with HOXB8

Gene Symbol	Gene ID	Gene Info
HOXB8 Ensembl NCBI GeneCards UniProt	ENSG00000120068.5	homeobox B8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_46695333_46695484	HOXB8	2930	0.098121	-0.80	1.0e-02	Click!
chr17_46696935_46697184	HOXB8	4581	0.080060	-0.76	1.7e-02	Click!
chr17_46690621_46690846	HOXB8	108	0.898450	-0.69	3.8e-02	Click!
chr17_46689590_46689741	HOXB8	1176	0.198765	-0.68	4.2e-02	Click!
chr17_46695682_46695990	HOXB8	3358	0.090943	-0.67	4.7e-02	Click!

Activity of the HOXB8 motif across conditions

Conditions sorted by the z-value of the HOXB8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_15498785_15499062	0.59	AGMO	alkylglycerol monooxygenase	93076	0.1
chr7_84765663_84765814	0.53	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	14487	0.32
chr8_118878705_118878856	0.49	EXT1	exostosin glycosyltransferase 1	243873	0.02
chr4_113437546_113438608	0.48	NEUROG2	neurogenin 2	749	0.58
chr5_95361917_95362068	0.48	ENSG00000207578	.	52850	0.12
chr1_23609794_23609945	0.47	HNRNPR	heterogeneous nuclear ribonucleoprotein R	60886	0.08
chr7_84253629_84253780	0.46	ENSG00000265050	.	41620	0.22
chr2_206185805_206185956	0.45	NRP2	neuropilin 2	361344	0.01
chr9_128256725_128256876	0.45	MAPKAP1	mitogen-activated protein kinase associated protein 1	10020	0.22
chr3_134182320_134182615	0.44	CEP63	centrosomal protein 63kDa	22118	0.15
chr5_143293259_143293410	0.44	HMHB1	histocompatibility (minor) HB-1	101608	0.08
chr3_151581991_151582142	0.43	SUCNR1	succinate receptor 1	9365	0.23
chr10_69865393_69865544	0.42	MYPN	myopalladin	444	0.84
chr8_131417344_131417495	0.42	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	3202	0.4
chr5_167791618_167792032	0.42	WWC1	WW and C2 domain containing 1	6601	0.29
chr2_69793604_69794058	0.41	ENSG00000207016	.	46525	0.13
chr11_9842791_9843084	0.40	RP11-1H15.2		17753	0.15
chr12_132488838_132488989	0.40	ENSG00000271905	.	2593	0.25
chr10_29932554_29932705	0.40	SVIL	supervillin	8728	0.22
chr4_114305617_114305768	0.40	ANK2	ankyrin 2, neuronal	11177	0.22
chr8_41054271_41054422	0.40	ENSG00000263372	.	74316	0.09
chr7_116418433_116418704	0.39	MET	met proto-oncogene	1339	0.49
chr19_381111_381262	0.39	THEG	theg spermatid protein	5173	0.15
chr12_93179700_93179851	0.39	EEA1	early endosome antigen 1	35100	0.18
chr2_216294982_216295133	0.39	FN1	fibronectin 1	5733	0.24
chr6_17429475_17429626	0.38	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	35607	0.21
chr2_84766841_84767171	0.38	DNAH6	dynein, axonemal, heavy chain 6	22063	0.25
chr2_27905704_27905855	0.38	SUPT7L	suppressor of Ty 7 (S. cerevisiae)-like	19103	0.11
chr13_32331269_32331420	0.38	RXFP2	relaxin/insulin-like family peptide receptor 2	17665	0.29
chr1_181110732_181111665	0.38	IER5	immediate early response 5	53560	0.15
chr14_71881120_71881271	0.38	ENSG00000207444	.	16141	0.22
chr11_121336559_121337538	0.38	RP11-730K11.1		13326	0.24
chr4_154434080_154434421	0.37	KIAA0922	KIAA0922	42798	0.17
chr11_65045369_65045520	0.37	POLA2	polymerase (DNA directed), alpha 2, accessory subunit	4534	0.15
chr2_174985205_174985356	0.37	OLA1	Obg-like ATPase 1	97394	0.07
chr18_21207750_21207901	0.37	ANKRD29	ankyrin repeat domain 29	21661	0.17
chr7_87941676_87941827	0.37	STEAP4	STEAP family member 4	5545	0.25
chr17_79542900_79543051	0.37	ENSG00000207021	.	2459	0.15
chr14_53342942_53343093	0.36	FERMT2	fermitin family member 2	11778	0.23
chr11_130717130_130717402	0.36	SNX19	sorting nexin 19	46503	0.19
chr6_113684543_113684694	0.36	ENSG00000222677	.	151571	0.04
chr7_89900753_89900904	0.36	C7orf63	chromosome 7 open reading frame 63	75	0.95
chr13_38289097_38289248	0.36	TRPC4	transient receptor potential cation channel, subfamily C, member 4	68298	0.13
chr3_47844781_47845806	0.36	DHX30	DEAH (Asp-Glu-Ala-His) box helicase 30	638	0.69
chr8_25771009_25771433	0.36	EBF2	early B-cell factor 2	25789	0.27
chr7_25891719_25892347	0.35	ENSG00000199085	.	97573	0.09
chr2_28079220_28079371	0.35	RBKS	ribokinase	13267	0.18
chr18_6730887_6731038	0.35	ARHGAP28	Rho GTPase activating protein 28	920	0.46
chr12_96199249_96199495	0.35	RP11-536G4.1	Uncharacterized protein	2497	0.23
chr18_60002993_60003265	0.35	ENSG00000199867	.	5084	0.19
chrX_138971819_138971970	0.35	ENSG00000221375	.	4254	0.21
chr2_217461850_217462001	0.34	AC073321.3		9736	0.19
chr15_70994047_70994198	0.34	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	498	0.86
chr14_92620421_92620697	0.34	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	964	0.57
chr7_41174850_41175131	0.34	AC005160.3		359833	0.01
chr6_149189778_149189929	0.34	RP11-162J8.2		95967	0.08
chr14_50691962_50692201	0.34	SOS2	son of sevenless homolog 2 (Drosophila)	5946	0.22
chr4_144318381_144318532	0.34	GAB1	GRB2-associated binding protein 1	5793	0.26
chr11_12560979_12561130	0.34	PARVA	parvin, alpha	86772	0.09
chr5_52785845_52785996	0.33	FST	follistatin	5874	0.3
chr5_5340745_5341045	0.33	KIAA0947	KIAA0947	81912	0.11
chr1_192412658_192412809	0.33	ENSG00000221145	.	47617	0.17
chr15_49231600_49231751	0.33	RP11-138E16.1		1242	0.44
chr1_205905941_205906092	0.33	SLC26A9	solute carrier family 26 (anion exchanger), member 9	1066	0.47
chr12_11120355_11120506	0.33	TAS2R50	taste receptor, type 2, member 50	19081	0.11
chr22_32042185_32042407	0.33	PISD	phosphatidylserine decarboxylase	7865	0.21
chr2_201626361_201626512	0.33	ENSG00000201737	.	13871	0.15
chr7_22142934_22143230	0.33	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	90445	0.09
chr1_185938815_185938966	0.33	HMCN1	hemicentin 1	201629	0.02
chr10_33304516_33304667	0.33	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	9871	0.23
chr13_80350445_80350596	0.33	NDFIP2	Nedd4 family interacting protein 2	294932	0.01
chr15_71080718_71080869	0.32	RP11-138H8.3		9586	0.19
chr8_62634134_62634577	0.32	ENSG00000264408	.	7008	0.24
chr3_8783509_8783660	0.32	CAV3	caveolin 3	8032	0.14
chr2_242318207_242318358	0.32	FARP2	FERM, RhoGEF and pleckstrin domain protein 2	6018	0.17
chr3_149867742_149867893	0.32	RP11-167H9.4		51998	0.14
chr2_214052099_214052250	0.32	IKZF2	IKAROS family zinc finger 2 (Helios)	35023	0.22
chr2_217968796_217968947	0.32	ENSG00000251849	.	72350	0.12
chr4_89647157_89647308	0.32	FAM13A-AS1	FAM13A antisense RNA 1	4366	0.21
chr2_67628597_67628898	0.32	ETAA1	Ewing tumor-associated antigen 1	4296	0.38
chr20_33166706_33166857	0.32	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20259	0.16
chr11_75798073_75798350	0.32	UVRAG	UV radiation resistance associated	28746	0.17
chr2_200307971_200308122	0.32	SATB2	SATB homeobox 2	12765	0.23
chr2_145700394_145700545	0.32	ENSG00000253036	.	392169	0.01
chr3_176843598_176843767	0.32	ENSG00000200882	.	226	0.94
chr3_101893892_101894043	0.32	ZPLD1	zona pellucida-like domain containing 1	75879	0.12
chr10_61192443_61192594	0.32	FAM13C	family with sequence similarity 13, member C	69579	0.13
chr4_89740050_89740544	0.32	FAM13A	family with sequence similarity 13, member A	4055	0.31
chr7_36487948_36488099	0.32	AC006960.7		14609	0.19
chr13_97959313_97959591	0.31	MBNL2	muscleblind-like splicing regulator 2	30994	0.21
chr13_74792422_74792795	0.31	ENSG00000206617	.	70743	0.12
chr8_6335605_6335756	0.31	RP11-115C21.2		71017	0.1
chr1_165860927_165861223	0.31	UCK2	uridine-cytidine kinase 2	3732	0.24
chr3_8978587_8978738	0.31	ENSG00000199815	.	5483	0.23
chr1_170777177_170777328	0.31	MROH9	maestro heat-like repeat family member 9	127360	0.05
chr6_113771019_113771170	0.31	ENSG00000222677	.	65095	0.14
chr4_88720136_88720287	0.31	IBSP	integrin-binding sialoprotein	522	0.76
chr20_5021981_5022132	0.31	ENSG00000266199	.	15691	0.16
chr22_30014073_30014247	0.31	NF2	neurofibromin 2 (merlin)	14172	0.16
chr2_192121899_192122050	0.31	MYO1B	myosin IB	5751	0.29
chr18_46866975_46867126	0.31	DYM	dymeclin	28017	0.18
chr17_39415242_39415393	0.31	KRTAP9-9	keratin associated protein 9-9	3681	0.09
chr3_27565025_27565176	0.31	ENSG00000201033	.	9738	0.2
chr1_92048607_92048758	0.31	CDC7	cell division cycle 7	81987	0.11
chr1_56098686_56098837	0.31	ENSG00000272051	.	148116	0.04
chr12_90485587_90485738	0.31	ENSG00000252823	.	337826	0.01
chr2_161225682_161226020	0.31	ENSG00000252465	.	27628	0.18
chr13_31784035_31784377	0.30	B3GALTL	beta 1,3-galactosyltransferase-like	10133	0.27
chr5_77531337_77531488	0.30	AP3B1	adaptor-related protein complex 3, beta 1 subunit	59104	0.13
chr13_94050738_94050889	0.30	ENSG00000252365	.	29600	0.26
chr15_49967575_49967726	0.30	RP11-353B9.1		23314	0.2
chr1_88422818_88422969	0.30	ENSG00000199318	.	503837	0.0
chr10_33932286_33932437	0.30	NRP1	neuropilin 1	307171	0.01
chr6_113011776_113011927	0.30	ENSG00000252215	.	158467	0.04
chr4_188539699_188539850	0.30	ZFP42	ZFP42 zinc finger protein	377151	0.01
chr8_61444637_61444969	0.30	RAB2A	RAB2A, member RAS oncogene family	15063	0.21
chr8_119427039_119427190	0.30	AC023590.1	Uncharacterized protein	132633	0.05
chr6_86172282_86172433	0.30	NT5E	5'-nucleotidase, ecto (CD73)	8742	0.27
chr15_96817381_96817630	0.30	NR2F2-AS1	NR2F2 antisense RNA 1	1720	0.37
chr10_112711676_112711827	0.30	SHOC2	soc-2 suppressor of clear homolog (C. elegans)	12858	0.15
chr2_1657675_1657826	0.30	AC144450.1		33865	0.19
chr8_23268879_23269030	0.29	LOXL2	lysyl oxidase-like 2	7201	0.19
chr11_12791941_12792092	0.29	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	25428	0.2
chr12_118628458_118628609	0.29	TAOK3	TAO kinase 3	177	0.96
chr4_188524604_188524755	0.29	ZFP42	ZFP42 zinc finger protein	392246	0.01
chr3_40085086_40085237	0.29	MYRIP	myosin VIIA and Rab interacting protein	56341	0.14
chr2_68100081_68100232	0.29	C1D	C1D nuclear receptor corepressor	189958	0.03
chr6_11973883_11974034	0.29	RP11-456H18.1		18287	0.24
chr2_86289069_86289220	0.29	POLR1A	polymerase (RNA) I polypeptide A, 194kDa	44134	0.12
chr2_26981757_26981908	0.29	SLC35F6	solute carrier family 35, member F6	5324	0.2
chr12_76345410_76345561	0.29	ENSG00000243420	.	6425	0.27
chr10_5114268_5114419	0.29	AKR1C3	aldo-keto reductase family 1, member C3	5487	0.16
chr10_33422454_33423119	0.29	ENSG00000263576	.	35222	0.17
chr3_124951031_124951182	0.29	SLC12A8	solute carrier family 12, member 8	19497	0.22
chr12_91316241_91316392	0.29	CCER1	coiled-coil glutamate-rich protein 1	32637	0.22
chr17_63660375_63660526	0.29	CEP112	centrosomal protein 112kDa	23307	0.26
chr17_79855827_79855978	0.29	NPB	neuropeptide B	2719	0.08
chr10_134224918_134226015	0.29	PWWP2B	PWWP domain containing 2B	14764	0.17
chr14_72117760_72117911	0.29	SIPA1L1	signal-induced proliferation-associated 1 like 1	32362	0.24
chr8_75673011_75673162	0.29	PI15	peptidase inhibitor 15	63686	0.13
chr1_112106719_112106870	0.29	ADORA3	adenosine A3 receptor	210	0.93
chr2_153226355_153226506	0.29	FMNL2	formin-like 2	34679	0.22
chr15_37351175_37351326	0.29	ENSG00000206676	.	8119	0.24
chr2_236574553_236574704	0.29	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	3620	0.34
chr6_125269183_125269334	0.29	RNF217	ring finger protein 217	14433	0.24
chr2_206970822_206970973	0.29	AC007383.4		9374	0.14
chr7_92645118_92645650	0.29	ENSG00000266794	.	44771	0.17
chr21_29050083_29050234	0.29	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	711326	0.0
chr3_17082338_17082489	0.29	PLCL2-AS1	PLCL2 antisense RNA 1	3271	0.3
chr1_180997388_180997539	0.29	STX6	syntaxin 6	5416	0.18
chr10_10834102_10834253	0.29	CELF2	CUGBP, Elav-like family member 2	213082	0.02
chr22_36748127_36749442	0.29	MYH9	myosin, heavy chain 9, non-muscle	12372	0.18
chr2_161162069_161162404	0.28	ENSG00000252465	.	91243	0.08
chr8_67443611_67443762	0.28	ENSG00000206949	.	30140	0.15
chr4_151067034_151067185	0.28	ENSG00000238721	.	63749	0.13
chr2_206621541_206621692	0.28	AC007362.3		7061	0.28
chr2_205416081_205416232	0.28	PARD3B	par-3 family cell polarity regulator beta	5433	0.36
chr18_32287372_32287523	0.28	DTNA	dystrobrevin, alpha	2801	0.37
chr21_28673144_28673295	0.28	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	334387	0.01
chr3_111527873_111528024	0.28	PHLDB2	pleckstrin homology-like domain, family B, member 2	50079	0.16
chr15_30180552_30180703	0.28	RP11-680F8.3		65793	0.11
chr10_133761353_133761504	0.28	PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	7895	0.25
chr17_48104312_48105191	0.28	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	28588	0.11
chr17_27952739_27952890	0.28	CORO6	coronin 6	2892	0.11
chrX_39832066_39832217	0.28	BCOR	BCL6 corepressor	90049	0.09
chr7_98047722_98048054	0.28	BAIAP2L1	BAI1-associated protein 2-like 1	17508	0.24
chr3_152049363_152049525	0.28	TMEM14E	transmembrane protein 14E	9335	0.23
chr2_225664643_225664794	0.28	DOCK10	dedicator of cytokinesis 10	12883	0.31
chr14_102537656_102538063	0.28	RP11-1017G21.4		5294	0.17
chr5_83689497_83689648	0.28	CTD-2269F5.1		8275	0.25
chr16_69074630_69074781	0.28	ENSG00000202497	.	33647	0.14
chr6_144737070_144737348	0.28	UTRN	utrophin	71972	0.12
chr2_56113502_56113653	0.28	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	36779	0.17
chr11_101987178_101987329	0.28	YAP1	Yes-associated protein 1	4008	0.2
chr4_123795223_123795374	0.28	RP11-170N16.3		10569	0.18
chr3_30323729_30323880	0.28	ENSG00000199927	.	22223	0.27
chr1_85755499_85756121	0.28	ENSG00000264380	.	5517	0.15
chr7_107670861_107671012	0.28	ENSG00000216085	.	6445	0.18
chr18_20898560_20898711	0.28	RP11-17J14.2		58317	0.13
chr1_100012381_100012668	0.28	PALMD	palmdelphin	98975	0.08
chr2_196602136_196602287	0.28	DNAH7	dynein, axonemal, heavy chain 7	18711	0.24
chr18_20124592_20124743	0.28	ENSG00000206827	.	102878	0.07
chr11_10948283_10948434	0.28	ZBED5-AS1	ZBED5 antisense RNA 1	61550	0.11
chr8_13130697_13130848	0.28	DLC1	deleted in liver cancer 1	3283	0.34
chr8_119890733_119890884	0.28	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	73631	0.11
chr1_41567718_41567869	0.28	SCMH1	sex comb on midleg homolog 1 (Drosophila)	57812	0.13
chr12_76404430_76404581	0.28	RP11-290L1.3		19769	0.17
chr15_39187982_39188133	0.28	C15orf53	chromosome 15 open reading frame 53	199258	0.03
chr4_123505443_123505702	0.28	IL21-AS1	IL21 antisense RNA 1	34566	0.18
chr12_28703830_28703981	0.28	CCDC91	coiled-coil domain containing 91	1908	0.45
chr17_39114507_39114658	0.28	KRT39	keratin 39	8562	0.08
chr3_100784256_100784407	0.27	ABI3BP	ABI family, member 3 (NESH) binding protein	71972	0.11
chr7_33684637_33684788	0.27	RP11-89N17.1	HCG1643653; Uncharacterized protein	80881	0.1
chr7_65520174_65520325	0.27	ENSG00000252997	.	1056	0.49
chr3_123265492_123265643	0.27	PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	37835	0.15
chr15_48857629_48857780	0.27	FBN1	fibrillin 1	80214	0.1
chr1_244516671_244516927	0.27	C1orf100	chromosome 1 open reading frame 100	862	0.69
chr1_184132614_184132871	0.27	ENSG00000199840	.	8215	0.28
chr5_86490215_86490366	0.27	AC008394.1	Uncharacterized protein	44532	0.14
chr18_32287605_32287756	0.27	DTNA	dystrobrevin, alpha	2568	0.38

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	0.3	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3	0.8	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	0.5	GO:0007132	meiotic metaphase I(GO:0007132)
0.2	1.0	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2	0.5	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2	0.6	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.6	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.6	GO:0070141	response to UV-A(GO:0070141)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.4	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.4	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.5	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.1	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.6	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.4	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:0050942	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.3	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.9	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.4	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.5	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	1.1	GO:0035329	hippo signaling(GO:0035329)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.3	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.3	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:0060206	estrous cycle phase(GO:0060206)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.2	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.1	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.2	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.2	GO:0008218	bioluminescence(GO:0008218)
0.1	1.3	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.4	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.1	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.3	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.2	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.3	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.3	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.4	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.2	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.4	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.1	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0033079	immature T cell proliferation(GO:0033079)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	1.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.6	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.2	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046) iris morphogenesis(GO:0061072)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0021591	ventricular system development(GO:0021591)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.2	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.2	GO:0071456	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.3	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.2	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.1	GO:0090504	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.3	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.5	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.2	GO:0006622	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.3	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.3	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.2	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.4	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.1	GO:0009415	response to water(GO:0009415)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619) male courtship behavior(GO:0008049)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.0	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940)
0.0	1.2	GO:0060271	cilium morphogenesis(GO:0060271)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.1	GO:0009820	alkaloid metabolic process(GO:0009820)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.1	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0010224	response to UV-B(GO:0010224)
0.0	0.1	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.2	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0015793	glycerol transport(GO:0015793)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.0	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0010092	organ induction(GO:0001759) specification of organ identity(GO:0010092)
0.0	0.1	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0042748	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.4	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0060688	regulation of morphogenesis of a branching structure(GO:0060688)
0.0	0.1	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0010896	regulation of triglyceride catabolic process(GO:0010896)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.0	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.1	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0042461	photoreceptor cell development(GO:0042461)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.0	GO:0042482	positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.5	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0090197	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.5	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.7	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.7	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.6	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.5	GO:0043256	laminin complex(GO:0043256)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.4	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.2	GO:0005827	polar microtubule(GO:0005827)
0.1	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	1.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	1.5	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	2.9	GO:0030016	myofibril(GO:0030016)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	1.2	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	4.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.7	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.5	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.0	GO:0042641	actomyosin(GO:0042641)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.4	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0030990	intraciliary transport particle(GO:0030990)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.6	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.0	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	1.0	GO:0017166	vinculin binding(GO:0017166)
0.1	0.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.4	GO:0042805	actinin binding(GO:0042805)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.1	3.0	GO:0005518	collagen binding(GO:0005518)
0.1	0.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	1.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0003896	DNA primase activity(GO:0003896)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.2	GO:0031013	troponin I binding(GO:0031013)
0.1	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.2	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.1	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:0043495	protein anchor(GO:0043495)
0.1	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.4	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.2	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.6	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.5	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.3	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.4	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0019798	procollagen-proline 3-dioxygenase activity(GO:0019797) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.0	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	1.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.3	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.3	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.8	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.0	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	1.1	PID ARF 3PATHWAY	Arf1 pathway
0.1	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	4.3	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	2.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.5	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events

Results for HOXB8

Z-value: 1.30

Motif logo

Transcription factors associated with HOXB8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXB8 motif across conditions

Conditions sorted by the z-value of the HOXB8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: