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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HOXC11

Z-value: 0.40

Motif logo

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 homeobox C11

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_54367610_54367772HOXC117790.2891260.491.9e-01Click!
chr12_54366324_54366475HOXC115110.5033070.255.2e-01Click!

Activity of the HOXC11 motif across conditions

Conditions sorted by the z-value of the HOXC11 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_7958757_7958908 0.11 PTPRM
 protein tyrosine phosphatase, receptor type, M
 11880
 0.23
chr5_16493939_16494090 0.10 FAM134B
 family with sequence similarity 134, member B
 15093
 0.21
chr1_82265506_82265657 0.09 LPHN2
 latrophilin 2
 501
 0.89
chr1_170631689_170631840 0.09 PRRX1
 paired related homeobox 1
 511
 0.87
chr5_80263913_80264064 0.09 CTC-459I6.1
7262
 0.24
chr1_158913144_158913295 0.09 PYHIN1
 pyrin and HIN domain family, member 1
 11861
 0.21
chr3_73595877_73596028 0.08 PDZRN3
 PDZ domain containing ring finger 3
 14817
 0.24
chr10_112506565_112506716 0.08 ENSG00000252036
 .
 9574
 0.18
chr6_45632042_45632279 0.08 ENSG00000252738
 .
 18319
 0.29
chr6_35362532_35362683 0.07 PPARD
 peroxisome proliferator-activated receptor delta
 52205
 0.1
chr12_52673287_52673438 0.07 RP11-845M18.7
422
 0.69
chr2_69894789_69894940 0.07 ENSG00000238708
 .
 373
 0.88
chr5_64493902_64494516 0.07 ENSG00000207439
 .
 75013
 0.12
chr13_99961636_99961787 0.07 GPR183
 G protein-coupled receptor 183
 2052
 0.34
chr20_42474741_42474892 0.07 ENSG00000206801
 .
 49633
 0.14
chr4_39531124_39531275 0.07 UGDH
 UDP-glucose 6-dehydrogenase
 1268
 0.35
chr3_73072628_73072858 0.07 ENSG00000238959
 .
 4216
 0.2
chr2_88920682_88920833 0.07 EIF2AK3
 eukaryotic translation initiation factor 2-alpha kinase 3
 3690
 0.2
chr1_83031153_83031304 0.07 LPHN2
 latrophilin 2
 585655
 0.0
chr6_64516560_64517136 0.07 RP11-59D5__B.2
119
 0.98
chr2_192182945_192183393 0.07 MYO1B
 myosin IB
 41558
 0.17
chr2_175766480_175766631 0.07 CHN1
 chimerin 1
 54076
 0.13
chr6_163849459_163849641 0.07 QKI
 QKI, KH domain containing, RNA binding
 5310
 0.35
chr2_197056759_197056910 0.07 STK17B
 serine/threonine kinase 17b
 15607
 0.18
chr9_5465910_5466061 0.07 CD274
 CD274 molecule
 15460
 0.19
chr18_56353868_56354019 0.07 RP11-126O1.4
9097
 0.15
chr7_114871692_114871916 0.07 ENSG00000199764
 .
 23754
 0.28
chr16_27252390_27252716 0.07 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 8154
 0.17
chr20_19973253_19973404 0.07 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 24432
 0.19
chr1_94792467_94792618 0.07 ARHGAP29
 Rho GTPase activating protein 29
 89353
 0.08
chr20_5755973_5756124 0.07 C20orf196
 chromosome 20 open reading frame 196
 24949
 0.22
chr4_38685842_38686144 0.06 RP11-617D20.1
19489
 0.15
chr3_115719451_115719602 0.06 ENSG00000243359
 .
 162811
 0.04
chr3_142919123_142919274 0.06 ENSG00000211483
 .
 34708
 0.19
chr16_1666082_1666233 0.06 CRAMP1L
 Crm, cramped-like (Drosophila)
 1516
 0.23
chr7_150440672_150440823 0.06 GIMAP5
 GTPase, IMAP family member 5
 6311
 0.17
chr3_172033208_172033359 0.06 AC092964.1
 Uncharacterized protein
 935
 0.62
chr2_239693558_239693739 0.06 TWIST2
 twist family bHLH transcription factor 2
 63025
 0.13
chr15_60085307_60085458 0.06 BNIP2
 BCL2/adenovirus E1B 19kDa interacting protein 2
 103649
 0.06
chr2_64750645_64750930 0.06 AFTPH
 aftiphilin
 678
 0.74
chr17_55723600_55723751 0.06 ENSG00000242889
 .
 28206
 0.16
chr8_141125038_141125212 0.06 C8orf17
 chromosome 8 open reading frame 17
 181709
 0.03
chr6_128529618_128529908 0.06 PTPRK
 protein tyrosine phosphatase, receptor type, K
 113563
 0.07
chr2_73334235_73334398 0.06 RAB11FIP5
 RAB11 family interacting protein 5 (class I)
 5830
 0.18
chr5_139678742_139678893 0.06 PFDN1
 prefoldin subunit 1
 3851
 0.19
chrX_39176359_39176510 0.06 ENSG00000207122
 .
 235896
 0.02
chr17_61433493_61433644 0.06 AC037445.1
17154
 0.15
chr6_18247333_18247484 0.06 DEK
 DEK oncogene
 2563
 0.28
chr2_40507984_40508135 0.06 AC007377.1
19912
 0.23
chr20_62169801_62169978 0.06 PTK6
 protein tyrosine kinase 6
 1166
 0.3
chr12_66005489_66005640 0.06 HMGA2
 high mobility group AT-hook 2
 212347
 0.02
chr16_69250892_69251043 0.06 RP11-70O5.2
23485
 0.11
chr3_180648116_180648267 0.06 FXR1
 fragile X mental retardation, autosomal homolog 1
 14943
 0.21
chr19_2215762_2215913 0.06 AC004490.1
273
 0.8
chr22_21978223_21978374 0.06 YDJC
 YdjC homolog (bacterial)
 6027
 0.1
chr5_38259654_38259805 0.06 EGFLAM
 EGF-like, fibronectin type III and laminin G domains
 1218
 0.54
chr20_24387296_24387447 0.06 SYNDIG1
 synapse differentiation inducing 1
 62464
 0.15
chr5_90476166_90476317 0.06 ENSG00000199643
 .
 90303
 0.1
chr4_39570957_39571108 0.06 UGDH
 UDP-glucose 6-dehydrogenase
 41101
 0.11
chr17_76531986_76532137 0.06 ENSG00000243426
 .
 2924
 0.23
chr7_104631689_104631965 0.06 ENSG00000251911
 .
 20093
 0.14
chr6_90854294_90854445 0.06 ENSG00000222078
 .
 143144
 0.04
chr6_158283594_158283745 0.06 RP11-52J3.2
12573
 0.17
chr17_62648244_62648405 0.06 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
 9706
 0.22
chr6_140084162_140084413 0.06 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 388530
 0.01
chr2_144504368_144504519 0.06 RP11-434H14.1
5580
 0.25
chr16_86817580_86817731 0.06 FOXL1
 forkhead box L1
 205540
 0.02
chr3_43386050_43386201 0.06 RP11-188P20.3
3010
 0.24
chr17_45959726_45959877 0.06 SP2
 Sp2 transcription factor
 13715
 0.1
chr5_172425652_172425803 0.06 ATP6V0E1
 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
 14893
 0.14
chr14_61125667_61125818 0.06 SIX1
 SIX homeobox 1
 765
 0.7
chr9_108011375_108011526 0.06 SLC44A1
 solute carrier family 44 (choline transporter), member 1
 4547
 0.34
chr5_172382388_172382600 0.06 RPL26L1
 ribosomal protein L26-like 1
 3238
 0.19
chrX_19778013_19778164 0.05 SH3KBP1
 SH3-domain kinase binding protein 1
 12267
 0.29
chr6_108486750_108487194 0.05 OSTM1
 osteopetrosis associated transmembrane protein 1
 72
 0.78
chr3_66529878_66530029 0.05 LRIG1
 leucine-rich repeats and immunoglobulin-like domains 1
 21403
 0.28
chr3_152808662_152808813 0.05 RP11-529G21.2
70827
 0.11
chr12_8230719_8230959 0.05 NECAP1
 NECAP endocytosis associated 1
 3968
 0.17
chr18_3252593_3253294 0.05 MYL12A
 myosin, light chain 12A, regulatory, non-sarcomeric
 670
 0.64
chr16_18925014_18925165 0.05 SMG1
 SMG1 phosphatidylinositol 3-kinase-related kinase
 2054
 0.25
chr9_20459022_20459173 0.05 ENSG00000222202
 .
 40778
 0.14
chr5_124201652_124202095 0.05 ZNF608
 zinc finger protein 608
 117373
 0.06
chr12_45227056_45227207 0.05 NELL2
 NEL-like 2 (chicken)
 42120
 0.18
chr1_170562549_170562700 0.05 RP11-576I22.2
60836
 0.12
chr17_37301012_37301163 0.05 PLXDC1
 plexin domain containing 1
 6815
 0.14
chr1_162541630_162541823 0.05 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
 5899
 0.17
chr17_73674018_73674169 0.05 RP11-474I11.8
1954
 0.18
chr12_66548262_66548413 0.05 TMBIM4
 transmembrane BAX inhibitor motif containing 4
 14954
 0.14
chr12_122592230_122592666 0.05 MLXIP
 MLX interacting protein
 19979
 0.18
chr3_171812873_171813024 0.05 FNDC3B
 fibronectin type III domain containing 3B
 31816
 0.22
chr16_53809610_53810340 0.05 FTO
 fat mass and obesity associated
 71881
 0.11
chr12_123243849_123244000 0.05 DENR
 density-regulated protein
 6553
 0.14
chr17_61857649_61857869 0.05 CCDC47
 coiled-coil domain containing 47
 4048
 0.14
chr16_49686147_49686298 0.05 ZNF423
 zinc finger protein 423
 11459
 0.24
chr7_140593399_140593550 0.05 ENSG00000271932
 .
 9602
 0.22
chr3_30668319_30669005 0.05 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 20569
 0.26
chr8_48648340_48648491 0.05 CEBPD
 CCAAT/enhancer binding protein (C/EBP), delta
 3233
 0.24
chr1_198533037_198533238 0.05 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 23062
 0.24
chr5_58187131_58187282 0.05 CTD-2176I21.2
27965
 0.22
chr18_61442167_61442318 0.05 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
 402
 0.88
chr14_72026196_72026347 0.05 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 26727
 0.25
chr5_176869820_176870094 0.05 PRR7-AS1
 PRR7 antisense RNA 1
 1521
 0.22
chr3_73481941_73482092 0.05 PDZRN3
 PDZ domain containing ring finger 3
 1039
 0.68
chr6_139492633_139492784 0.05 HECA
 headcase homolog (Drosophila)
 36459
 0.17
chr12_110992885_110993169 0.05 PPTC7
 PTC7 protein phosphatase homolog (S. cerevisiae)
 28098
 0.12
chr13_26636007_26636158 0.05 SHISA2
 shisa family member 2
 10913
 0.27
chr6_106643256_106643407 0.05 ENSG00000244710
 .
 88255
 0.07
chr11_116881940_116882091 0.05 ENSG00000264344
 .
 4230
 0.2
chr3_28391593_28391746 0.05 ZCWPW2
 zinc finger, CW type with PWWP domain 2
 1029
 0.41
chr2_25506534_25506685 0.05 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 31429
 0.17
chr11_121358351_121358610 0.05 RP11-730K11.1
34758
 0.19
chr8_42052077_42052228 0.05 PLAT
 plasminogen activator, tissue
 907
 0.54
chr13_99148708_99148963 0.05 STK24
 serine/threonine kinase 24
 22686
 0.19
chr7_66397167_66397485 0.05 TMEM248
 transmembrane protein 248
 1715
 0.35
chr7_28005907_28006058 0.05 JAZF1
 JAZF zinc finger 1
 25693
 0.23
chr8_132857197_132857348 0.05 EFR3A
 EFR3 homolog A (S. cerevisiae)
 59063
 0.16
chr5_70778847_70779136 0.05 BDP1
 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
 27549
 0.21
chr14_55140117_55140268 0.05 SAMD4A
 sterile alpha motif domain containing 4A
 81359
 0.1
chr12_67136436_67136587 0.05 GRIP1
 glutamate receptor interacting protein 1
 61249
 0.16
chr10_116634856_116635150 0.05 FAM160B1
 family with sequence similarity 160, member B1
 14453
 0.25
chr14_31663861_31664209 0.05 HECTD1
 HECT domain containing E3 ubiquitin protein ligase 1
 12654
 0.17
chr7_139452923_139453350 0.05 HIPK2
 homeodomain interacting protein kinase 2
 24381
 0.2
chr11_33769435_33769586 0.05 FBXO3
 F-box protein 3
 5435
 0.16
chr5_39025357_39025508 0.05 RICTOR
 RPTOR independent companion of MTOR, complex 2
 49059
 0.16
chr12_88728604_88728755 0.05 ENSG00000199245
 .
 95540
 0.09
chr1_230784406_230784557 0.05 COG2
 component of oligomeric golgi complex 2
 5924
 0.24
chr11_33295654_33295805 0.05 HIPK3
 homeodomain interacting protein kinase 3
 15852
 0.21
chr4_169752514_169752665 0.05 PALLD
 palladin, cytoskeletal associated protein
 567
 0.7
chr1_186271695_186271846 0.05 PRG4
 proteoglycan 4
 6359
 0.19
chr8_24013639_24013790 0.05 ENSG00000207201
 .
 79043
 0.11
chr8_48254486_48254637 0.05 SPIDR
 scaffolding protein involved in DNA repair
 81004
 0.1
chrX_31284130_31284281 0.05 DMD
 dystrophin
 769
 0.77
chr1_25771368_25771519 0.05 TMEM57
 transmembrane protein 57
 14032
 0.15
chr7_7691133_7691284 0.05 RPA3
 replication protein A3, 14kDa
 10605
 0.26
chr3_56501411_56501562 0.05 ERC2
 ELKS/RAB6-interacting/CAST family member 2
 905
 0.72
chr5_179975750_179975903 0.05 CNOT6
 CCR4-NOT transcription complex, subunit 6
 19551
 0.16
chrX_94314503_94314654 0.05 ENSG00000221187
 .
 3647
 0.36
chr9_91151964_91152115 0.05 NXNL2
 nucleoredoxin-like 2
 2019
 0.47
chr2_10121974_10122125 0.05 GRHL1
 grainyhead-like 1 (Drosophila)
 13385
 0.16
chr15_39923761_39923912 0.05 FSIP1
 fibrous sheath interacting protein 1
 30709
 0.17
chr2_230763302_230763453 0.05 ENSG00000222344
 .
 4315
 0.18
chr9_21560365_21560626 0.04 MIR31HG
 MIR31 host gene (non-protein coding)
 827
 0.62
chr1_92040002_92040153 0.04 CDC7
 cell division cycle 7
 73382
 0.12
chr13_52390546_52391185 0.04 RP11-327P2.5
12432
 0.19
chr8_107160982_107161133 0.04 ENSG00000251003
 .
 88305
 0.1
chr2_38593562_38593713 0.04 ATL2
 atlastin GTPase 2
 9729
 0.29
chr1_24022876_24023104 0.04 RPL11
 ribosomal protein L11
 3891
 0.19
chr12_67355616_67355767 0.04 GRIP1
 glutamate receptor interacting protein 1
 157725
 0.04
chr16_67538677_67538891 0.04 FAM65A
 family with sequence similarity 65, member A
 13537
 0.09
chr18_73122194_73122345 0.04 RP11-321M21.3
 HCG1996301; Uncharacterized protein
 3302
 0.31
chr6_157148026_157148177 0.04 RP11-230C9.3
46512
 0.15
chr10_77879085_77879236 0.04 ENSG00000221232
 .
 7909
 0.3
chr13_75018542_75018693 0.04 LINC00381
 long intergenic non-protein coding RNA 381
 25307
 0.21
chr12_78412506_78412657 0.04 NAV3
 neuron navigator 3
 52525
 0.17
chr2_26465301_26465452 0.04 HADHB
 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
 662
 0.66
chr17_41739555_41740247 0.04 MEOX1
 mesenchyme homeobox 1
 579
 0.74
chr10_89705727_89705964 0.04 ENSG00000200891
 .
 48607
 0.13
chr1_113007964_113008322 0.04 WNT2B
 wingless-type MMTV integration site family, member 2B
 1020
 0.58
chr17_60132149_60132300 0.04 MED13
 mediator complex subunit 13
 10419
 0.17
chr17_77944274_77944425 0.04 TBC1D16
 TBC1 domain family, member 16
 18537
 0.16
chr12_1875760_1875911 0.04 CACNA2D4
 calcium channel, voltage-dependent, alpha 2/delta subunit 4
 45051
 0.13
chr13_25034322_25034473 0.04 TPTE2P6
 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 6
 52102
 0.12
chr9_137418567_137418718 0.04 COL5A1
 collagen, type V, alpha 1
 114978
 0.05
chr5_98261626_98261777 0.04 CHD1
 chromodomain helicase DNA binding protein 1
 539
 0.8
chr11_110167983_110168234 0.04 RDX
 radixin
 661
 0.83
chr16_72281999_72282150 0.04 PMFBP1
 polyamine modulated factor 1 binding protein 1
 71297
 0.1
chr2_118769373_118769761 0.04 CCDC93
 coiled-coil domain containing 93
 2142
 0.23
chr17_70358516_70358667 0.04 SOX9
 SRY (sex determining region Y)-box 9
 241430
 0.02
chr17_78762568_78762807 0.04 RP11-28G8.1
16745
 0.23
chr14_89078082_89078377 0.04 ZC3H14
 zinc finger CCCH-type containing 14
 4601
 0.21
chr16_21311524_21311721 0.04 CRYM
 crystallin, mu
 2750
 0.29
chr13_27706090_27706241 0.04 USP12-AS1
 USP12 antisense RNA 1
 30827
 0.15
chr13_114862694_114862923 0.04 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 11487
 0.22
chr18_67232011_67232162 0.04 RP11-465I4.2
53844
 0.17
chr21_43061018_43061225 0.04 ENSG00000252771
 .
 36278
 0.17
chr1_225843948_225844099 0.04 ENAH
 enabled homolog (Drosophila)
 3179
 0.27
chr19_11146514_11146699 0.04 SMARCA4
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
 5117
 0.16
chr1_31123601_31123752 0.04 MATN1-AS1
 MATN1 antisense RNA 1
 67675
 0.1
chr11_95984153_95984304 0.04 ENSG00000266192
 .
 90374
 0.08
chr14_90797503_90797880 0.04 NRDE2
 NRDE-2, necessary for RNA interference, domain containing
 588
 0.77
chr8_714573_714724 0.04 ERICH1-AS1
 ERICH1 antisense RNA 1
 26906
 0.18
chr2_87552860_87553169 0.04 IGKV3OR2-268
 immunoglobulin kappa variable 3/OR2-268 (non-functional)
 12620
 0.29
chr5_51968673_51968824 0.04 ITGA1
 integrin, alpha 1
 114982
 0.06
chr9_72878166_72878317 0.04 SMC5
 structural maintenance of chromosomes 5
 4304
 0.21
chr8_98565933_98566084 0.04 MTDH
 metadherin
 90399
 0.09
chr5_43554525_43554713 0.04 PAIP1
 poly(A) binding protein interacting protein 1
 1861
 0.28
chr6_44598460_44598611 0.04 ENSG00000266619
 .
 195157
 0.03
chr2_191513228_191513379 0.04 NAB1
 NGFI-A binding protein 1 (EGR1 binding protein 1)
 318
 0.91
chr13_33199858_33200009 0.04 PDS5B
 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
 39369
 0.19
chr5_95534441_95534647 0.04 ENSG00000206997
 .
 11387
 0.28
chr3_142754964_142755115 0.04 U2SURP
 U2 snRNP-associated SURP domain containing
 114
 0.97
chr8_61446627_61446778 0.04 RAB2A
 RAB2A, member RAS oncogene family
 16962
 0.2
chr1_107816447_107816598 0.04 NTNG1
 netrin G1
 125306
 0.06
chr15_78715144_78715338 0.04 IREB2
 iron-responsive element binding protein 2
 14532
 0.17
chr6_56598121_56598272 0.04 DST
 dystonin
 52481
 0.16
chr8_94927918_94928069 0.04 ENSG00000264448
 .
 354
 0.8
chr5_79447122_79447273 0.04 CTC-458I2.2
23013
 0.19
chrX_72782730_72782881 0.04 CHIC1
 cysteine-rich hydrophobic domain 1
 231
 0.96
chr12_127073806_127073957 0.04 ENSG00000239776
 .
 576791
 0.0
chr3_153850737_153851019 0.04 ARHGEF26
 Rho guanine nucleotide exchange factor (GEF) 26
 11649
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)