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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for HOXC12_HOXD12

Z-value: 0.96

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol	Gene ID	Gene Info
HOXC12 Ensembl NCBI GeneCards UniProt	ENSG00000123407.3	homeobox C12
HOXD12 Ensembl NCBI GeneCards UniProt	ENSG00000170178.5	homeobox D12

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_54349774_54349925	HOXC12	1231	0.220317	0.87	2.5e-03	Click!
chr12_54348570_54348721	HOXC12	27	0.934048	0.48	1.9e-01	Click!
chr12_54350955_54351106	HOXC12	2412	0.111909	0.46	2.1e-01	Click!
chr12_54347045_54347196	HOXC12	1498	0.180734	0.42	2.6e-01	Click!
chr12_54350731_54350882	HOXC12	2188	0.121324	0.38	3.2e-01	Click!
chr2_176961933_176962152	HOXD12	2416	0.127593	0.76	1.8e-02	Click!
chr2_176962600_176962751	HOXD12	1783	0.165787	0.74	2.3e-02	Click!
chr2_176961225_176961406	HOXD12	3143	0.107164	0.50	1.7e-01	Click!
chr2_176965032_176965183	HOXD12	577	0.525819	0.46	2.1e-01	Click!
chr2_176964824_176964975	HOXD12	369	0.704797	-0.35	3.6e-01	Click!

Activity of the HOXC12_HOXD12 motif across conditions

Conditions sorted by the z-value of the HOXC12_HOXD12 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_27199603_27199754	0.37	HOXA7	homeobox A7	2123	0.1
chr18_29620502_29620880	0.36	ENSG00000265063	.	20261	0.13
chr1_100917512_100917831	0.35	RP5-837M10.4		33882	0.17
chr9_100862555_100862740	0.33	TRIM14	tripartite motif containing 14	7804	0.19
chr21_19148494_19148866	0.32	AL109761.5		17125	0.22
chr13_99911046_99911220	0.32	GPR18	G protein-coupled receptor 18	451	0.83
chr6_489632_490047	0.31	RP1-20B11.2		34332	0.22
chr6_112310464_112310615	0.31	WISP3	WNT1 inducible signaling pathway protein 3	64736	0.11
chr7_30635395_30635896	0.29	ENSG00000196295	.	1220	0.36
chr14_95620236_95620590	0.29	DICER1	dicer 1, ribonuclease type III	3194	0.2
chr1_117359843_117360063	0.29	CD2	CD2 molecule	62864	0.1
chr2_198169561_198169772	0.29	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	2423	0.25
chr10_32619705_32619856	0.28	RP11-135A24.4		15647	0.13
chr7_104660086_104660248	0.27	KMT2E	lysine (K)-specific methyltransferase 2E	5259	0.17
chr22_40340142_40340424	0.27	GRAP2	GRB2-related adaptor protein 2	2538	0.26
chr18_29601432_29601640	0.27	RNF125	ring finger protein 125, E3 ubiquitin protein ligase	3201	0.21
chr17_66250172_66250736	0.26	AMZ2	archaelysin family metallopeptidase 2	4126	0.18
chr6_45562949_45563100	0.26	ENSG00000252738	.	50817	0.18
chr1_29252967_29253119	0.25	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	11952	0.18
chr2_136813885_136814194	0.25	AC093391.2		44004	0.15
chr13_40763533_40763684	0.24	ENSG00000207458	.	37356	0.23
chr12_62669088_62669395	0.24	USP15	ubiquitin specific peptidase 15	3168	0.27
chr2_134940695_134940917	0.24	ENSG00000222921	.	47960	0.15
chr19_42278293_42278624	0.24	AC011513.4		12343	0.12
chr1_111736243_111736511	0.24	DENND2D	DENN/MADD domain containing 2D	6934	0.12
chr12_54427356_54427507	0.23	ENSG00000207571	.	303	0.66
chr12_4758632_4758783	0.23	NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	434	0.49
chr3_32445074_32445225	0.23	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	11618	0.25
chr3_141989336_141989501	0.23	GK5	glycerol kinase 5 (putative)	44969	0.16
chr13_48982887_48983093	0.23	LPAR6	lysophosphatidic acid receptor 6	18053	0.26
chr11_128293469_128293620	0.23	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	81745	0.1
chr2_158269372_158269629	0.23	CYTIP	cytohesin 1 interacting protein	26426	0.19
chr17_46503456_46503859	0.23	SKAP1	src kinase associated phosphoprotein 1	3895	0.18
chr8_37738986_37739173	0.23	RAB11FIP1	RAB11 family interacting protein 1 (class I)	3444	0.18
chr14_99397580_99397874	0.23	C14orf177	chromosome 14 open reading frame 177	219770	0.02
chr16_14394801_14395003	0.23	ENSG00000207639	.	2922	0.25
chr14_91869257_91869590	0.23	CCDC88C	coiled-coil domain containing 88C	14267	0.23
chr12_9889248_9889774	0.23	CLECL1	C-type lectin-like 1	3616	0.19
chr10_126409005_126409284	0.22	FAM53B-AS1	FAM53B antisense RNA 1	16391	0.17
chr2_152663001_152663152	0.22	ARL5A	ADP-ribosylation factor-like 5A	21906	0.25
chr8_66868206_66868520	0.22	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	65432	0.13
chr12_21766880_21767202	0.22	GYS2	glycogen synthase 2 (liver)	9260	0.2
chr4_90224584_90224742	0.22	GPRIN3	GPRIN family member 3	4498	0.35
chr5_56137391_56137542	0.22	ENSG00000238717	.	15509	0.15
chr1_165615620_165615771	0.22	MGST3	microsomal glutathione S-transferase 3	14218	0.17
chrX_11783407_11783558	0.22	MSL3	male-specific lethal 3 homolog (Drosophila)	5735	0.33
chr2_109582380_109582745	0.22	EDAR	ectodysplasin A receptor	23163	0.25
chr16_47002248_47002399	0.22	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	4531	0.23
chr8_29959545_29959696	0.22	LEPROTL1	leptin receptor overlapping transcript-like 1	164	0.94
chr1_143768445_143768628	0.21	PPIAL4G	peptidylprolyl isomerase A (cyclophilin A)-like 4G	655	0.74
chr6_34643318_34643517	0.21	C6orf106	chromosome 6 open reading frame 106	3684	0.16
chr4_148982349_148982716	0.21	RP11-76G10.1		85090	0.1
chr1_101729987_101730176	0.21	RP4-575N6.5		21367	0.16
chr2_172950128_172950279	0.21	DLX1	distal-less homeobox 1	61	0.98
chr2_216985833_216985984	0.21	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	11834	0.2
chr2_235125609_235126070	0.21	SPP2	secreted phosphoprotein 2, 24kDa	166408	0.04
chr14_61869932_61870173	0.21	PRKCH	protein kinase C, eta	12640	0.24
chr6_130832933_130833235	0.21	ENSG00000202438	.	62173	0.12
chr15_60843099_60843250	0.21	CTD-2501E16.2		21002	0.18
chr19_35698577_35699072	0.21	FAM187B	family with sequence similarity 187, member B	20808	0.09
chr6_20410211_20410393	0.21	E2F3	E2F transcription factor 3	6268	0.16
chr3_51723451_51723884	0.20	ENSG00000201595	.	4931	0.17
chr9_4740243_4740450	0.20	AK3	adenylate kinase 3	881	0.61
chr18_2889433_2889584	0.20	RP11-737O24.5		31456	0.13
chr1_40863540_40863744	0.20	SMAP2	small ArfGAP2	1135	0.47
chr12_71117144_71117295	0.20	PTPRR	protein tyrosine phosphatase, receptor type, R	31154	0.22
chr1_158900042_158900193	0.20	PYHIN1	pyrin and HIN domain family, member 1	469	0.84
chr6_90983654_90983908	0.20	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	22680	0.22
chr8_27237001_27237352	0.20	PTK2B	protein tyrosine kinase 2 beta	992	0.62
chr3_101442895_101443275	0.20	CEP97	centrosomal protein 97kDa	316	0.86
chr6_42006686_42006952	0.20	CCND3	cyclin D3	9605	0.15
chrX_133508002_133508254	0.20	PHF6	PHD finger protein 6	725	0.68
chr9_98486374_98486879	0.20	DKFZP434H0512	Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512	47979	0.17
chr1_235371482_235371633	0.20	ARID4B	AT rich interactive domain 4B (RBP1-like)	5674	0.18
chr3_46467666_46467817	0.20	CCRL2	chemokine (C-C motif) receptor-like 2	18369	0.14
chr12_123354040_123354191	0.20	HIP1R	huntingtin interacting protein 1 related	9403	0.17
chr20_2093004_2093155	0.20	STK35	serine/threonine kinase 35	9525	0.24
chr3_71767666_71767942	0.20	EIF4E3	eukaryotic translation initiation factor 4E family member 3	6722	0.23
chr17_76772719_76772870	0.20	CYTH1	cytohesin 1	5560	0.2
chr2_102239339_102239566	0.20	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	73860	0.12
chr6_143111835_143111986	0.20	RP1-67K17.3		42330	0.17
chr8_66864395_66864582	0.20	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	69307	0.12
chr12_123362397_123362630	0.19	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)	12193	0.16
chr2_90413319_90413470	0.19	CH17-132F21.1	Uncharacterized protein	44807	0.14
chr9_123956488_123956761	0.19	RAB14	RAB14, member RAS oncogene family	7523	0.16
chr8_81699211_81699362	0.19	ENSG00000243951	.	10089	0.24
chr6_109357989_109358140	0.19	ENSG00000199944	.	22753	0.16
chr1_198657070_198657411	0.19	RP11-553K8.5		21050	0.23
chr16_53495579_53495893	0.19	RBL2	retinoblastoma-like 2 (p130)	11748	0.16
chr18_56428367_56428661	0.19	RP11-126O1.4		8552	0.18
chr11_72866229_72866512	0.19	FCHSD2	FCH and double SH3 domains 2	13064	0.2
chr2_54014889_54015239	0.19	ERLEC1	endoplasmic reticulum lectin 1	847	0.39
chr15_78396917_78397068	0.19	SH2D7	SH2 domain containing 7	12065	0.12
chr14_99732450_99732608	0.19	AL109767.1		3244	0.27
chr6_137087078_137087923	0.19	MAP3K5	mitogen-activated protein kinase kinase kinase 5	26156	0.19
chr15_58914890_58915041	0.19	ENSG00000239100	.	22531	0.17
chr19_20278605_20278756	0.19	ZNF486	zinc finger protein 486	597	0.72
chr13_26546132_26546283	0.19	ENSG00000223158	.	21248	0.19
chr6_17715455_17715606	0.19	ENSG00000201415	.	6604	0.16
chr5_75746391_75746683	0.19	IQGAP2	IQ motif containing GTPase activating protein 2	46288	0.18
chr11_108067830_108068158	0.19	ATM	ataxia telangiectasia mutated	25217	0.14
chr6_128223704_128223855	0.19	THEMIS	thymocyte selection associated	1553	0.54
chr2_99327218_99327512	0.19	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	15794	0.22
chr18_42307497_42307648	0.18	SETBP1	SET binding protein 1	30443	0.26
chr17_39491061_39491212	0.18	KRT33A	keratin 33A	15928	0.08
chr7_26238411_26238603	0.18	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	1859	0.27
chr8_64106613_64106764	0.18	YTHDF3	YTH domain family, member 3	6600	0.26
chr6_143235618_143235769	0.18	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	30645	0.22
chr18_60869534_60869685	0.18	ENSG00000238988	.	7711	0.24
chr1_167417574_167417925	0.18	RP11-104L21.2		10149	0.22
chr8_21436069_21436236	0.18	ENSG00000266630	.	28643	0.23
chr7_155091032_155091229	0.18	INSIG1	insulin induced gene 1	859	0.66
chr11_114043857_114044009	0.18	NNMT	nicotinamide N-methyltransferase	84620	0.08
chr11_128155775_128156003	0.18	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	219400	0.02
chr7_44524710_44524973	0.18	NUDCD3	NudC domain containing 3	5638	0.2
chr2_25518696_25518996	0.18	ENSG00000221445	.	32744	0.17
chr5_139784402_139784576	0.18	ANKHD1	ankyrin repeat and KH domain containing 1	2983	0.14
chr7_43612154_43612308	0.18	ENSG00000252308	.	6256	0.2
chr17_70724054_70724226	0.18	ENSG00000222545	.	13530	0.24
chr3_150469819_150470154	0.18	SIAH2-AS1	SIAH2 antisense RNA 1	9738	0.17
chr1_39657862_39658032	0.18	MACF1	microtubule-actin crosslinking factor 1	11971	0.17
chr6_131039218_131039369	0.18	SMLR1	small leucine-rich protein 1	109253	0.07
chr17_35032252_35032424	0.18	MRM1	mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)	73947	0.08
chr3_183416587_183416740	0.18	YEATS2	YEATS domain containing 2	1057	0.55
chr3_186763060_186763211	0.18	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	1604	0.46
chr11_74971779_74972056	0.18	CTD-2562J17.7		746	0.56
chr19_2699431_2699633	0.18	GNG7	guanine nucleotide binding protein (G protein), gamma 7	3175	0.15
chr11_46366304_46366455	0.18	DGKZ	diacylglycerol kinase, zeta	438	0.79
chr10_22903290_22903554	0.18	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	22780	0.26
chr8_79423337_79423629	0.18	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	4891	0.32
chrX_123146711_123147006	0.18	STAG2	stromal antigen 2	49838	0.15
chr6_112035271_112035422	0.18	FYN	FYN oncogene related to SRC, FGR, YES	5919	0.26
chr17_64669218_64669401	0.18	AC006947.1		3181	0.27
chr2_55519969_55520120	0.18	ENSG00000206964	.	6890	0.14
chr2_87838496_87838667	0.17	RP11-1399P15.1		61028	0.14
chr13_21120681_21121008	0.17	IFT88	intraflagellar transport 88 homolog (Chlamydomonas)	19741	0.18
chr21_45502434_45502585	0.17	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	24662	0.15
chr6_53406439_53406590	0.17	GCLC	glutamate-cysteine ligase, catalytic subunit	2892	0.28
chr8_41906339_41906551	0.17	KAT6A	K(lysine) acetyltransferase 6A	3060	0.26
chr1_6093691_6093842	0.17	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	577	0.74
chr17_28082190_28082341	0.17	RP11-82O19.1		5856	0.17
chr15_40409050_40409201	0.17	BMF	Bcl2 modifying factor	8032	0.16
chr13_21974174_21974456	0.17	ZDHHC20-IT1	ZDHHC20 intronic transcript 1 (non-protein coding)	22302	0.17
chr1_65416643_65416841	0.17	JAK1	Janus kinase 1	15445	0.24
chr15_75160514_75160760	0.17	SCAMP2	secretory carrier membrane protein 2	4744	0.12
chr7_143008536_143008687	0.17	CLCN1	chloride channel, voltage-sensitive 1	4608	0.11
chr9_117355290_117355468	0.17	ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	5353	0.16
chr11_14258542_14258717	0.17	RP11-21L19.1		36608	0.19
chr2_190440534_190440750	0.17	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	4971	0.27
chr14_91885821_91886016	0.17	CCDC88C	coiled-coil domain containing 88C	1730	0.44
chr1_27796857_27797047	0.17	WASF2	WAS protein family, member 2	19610	0.16
chr20_50058396_50058617	0.17	ENSG00000266761	.	11008	0.26
chr4_81461619_81461770	0.17	C4orf22	chromosome 4 open reading frame 22	204771	0.03
chr17_58472537_58472688	0.17	C17orf64	chromosome 17 open reading frame 64	2822	0.26
chr2_235355709_235355860	0.17	ARL4C	ADP-ribosylation factor-like 4C	49460	0.19
chr1_36396160_36396311	0.17	AGO3	argonaute RISC catalytic component 3	84	0.97
chr5_133552527_133552678	0.17	PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	7482	0.15
chr10_6559761_6559912	0.17	PRKCQ	protein kinase C, theta	62365	0.15
chr7_142425089_142425240	0.17	PRSS1	protease, serine, 1 (trypsin 1)	32155	0.16
chr2_48673055_48673250	0.17	PPP1R21	protein phosphatase 1, regulatory subunit 21	4884	0.25
chr2_144047706_144047857	0.17	RP11-190J23.1		118040	0.06
chr1_2425366_2425939	0.17	RP3-395M20.3		266	0.78
chr5_96213863_96214014	0.17	ERAP2	endoplasmic reticulum aminopeptidase 2	1330	0.4
chr9_74397408_74397580	0.17	TMEM2	transmembrane protein 2	13694	0.28
chr10_102269880_102270031	0.17	SEC31B	SEC31 homolog B (S. cerevisiae)	9636	0.16
chr6_159439270_159439421	0.17	RP1-111C20.4		7633	0.19
chr22_46469795_46469946	0.17	RP6-109B7.4		4099	0.12
chr3_56711954_56712231	0.16	FAM208A	family with sequence similarity 208, member A	4953	0.31
chr1_181012158_181012309	0.16	MR1	major histocompatibility complex, class I-related	9094	0.18
chr2_197994431_197994637	0.16	ANKRD44	ankyrin repeat domain 44	7077	0.27
chr5_49928190_49928375	0.16	PARP8	poly (ADP-ribose) polymerase family, member 8	33451	0.25
chr14_98641364_98641616	0.16	ENSG00000222066	.	156597	0.04
chr17_28031238_28031461	0.16	RP11-82O19.1		56772	0.07
chr11_14749423_14749574	0.16	PDE3B	phosphodiesterase 3B, cGMP-inhibited	84121	0.09
chr7_94024593_94024785	0.16	COL1A2	collagen, type I, alpha 2	816	0.74
chr5_36168240_36168391	0.16	ENSG00000201223	.	13094	0.13
chr5_93282912_93283063	0.16	RP11-549J18.1		83456	0.1
chr1_26440061_26440413	0.16	PDIK1L	PDLIM1 interacting kinase 1 like	1897	0.22
chr16_68313683_68314095	0.16	ENSG00000252026	.	4332	0.09
chr6_42362610_42362875	0.16	ENSG00000221252	.	17392	0.21
chr3_50607030_50607235	0.16	HEMK1	HemK methyltransferase family member 1	208	0.89
chr13_31201174_31201431	0.16	USPL1	ubiquitin specific peptidase like 1	9382	0.23
chr13_43599268_43599629	0.16	DNAJC15	DnaJ (Hsp40) homolog, subfamily C, member 15	2109	0.42
chr9_92083234_92083501	0.16	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	11438	0.23
chr5_37841386_37841537	0.16	GDNF	glial cell derived neurotrophic factor	1673	0.47
chr20_13211124_13211275	0.16	ISM1	isthmin 1, angiogenesis inhibitor	8781	0.2
chr9_37302958_37303110	0.16	ENSG00000216070	.	6933	0.22
chr3_143472000_143472151	0.16	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	95225	0.09
chr1_167907091_167907242	0.16	MPC2	mitochondrial pyruvate carrier 2	888	0.44
chr5_86658413_86658564	0.16	CTC-428H11.2		14509	0.19
chr6_91124113_91124295	0.16	ENSG00000252676	.	32287	0.22
chr2_70336914_70337228	0.16	PCBP1-AS1	PCBP1 antisense RNA 1	21093	0.14
chr1_84637970_84638121	0.16	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	7396	0.29
chr8_134068581_134068794	0.16	SLA	Src-like-adaptor	3916	0.29
chr2_61198515_61198962	0.16	ENSG00000222251	.	27149	0.15
chr14_23029796_23030088	0.16	AE000662.93		3986	0.13
chr1_173838796_173839175	0.16	ZBTB37	zinc finger and BTB domain containing 37	891	0.39
chr10_6625139_6625442	0.16	PRKCQ	protein kinase C, theta	3027	0.4
chr1_222594663_222594814	0.16	ENSG00000222399	.	82339	0.09
chr14_98173448_98173821	0.16	RP11-204N11.1	Uncharacterized protein	55534	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.2	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.1	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:2000380	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.0	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.3	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.2	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:2000041	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0	0.3	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.2	GO:0002834	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.4	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.2	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.0	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	1.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.3	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0021819	cerebral cortex radial glia guided migration(GO:0021801) layer formation in cerebral cortex(GO:0021819) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0021683	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.0	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.3	GO:0000718	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	1.0	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.0	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.2	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0016073	snRNA metabolic process(GO:0016073)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.4	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	GO:0071942	XPC complex(GO:0071942)
0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	GO:0000791	euchromatin(GO:0000791)
0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	GO:0072487	MSL complex(GO:0072487)
0.1	GO:0005827	polar microtubule(GO:0005827)
0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	GO:0070695	FHF complex(GO:0070695)
0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.3	GO:0001772	immunological synapse(GO:0001772)
0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	GO:0031932	TORC2 complex(GO:0031932)
0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	GO:0000124	SAGA complex(GO:0000124)
0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	GO:0042599	lamellar body(GO:0042599)
0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1	GO:0030891	VCB complex(GO:0030891)
0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	GO:0001652	granular component(GO:0001652)
0.0	GO:0031904	endosome lumen(GO:0031904)
0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	GO:0000796	condensin complex(GO:0000796)
0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1	GO:0034451	centriolar satellite(GO:0034451)
0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.1	GO:0005683	U7 snRNP(GO:0005683)
0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.3	GO:0031519	PcG protein complex(GO:0031519)
0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.2	GO:0016235	aggresome(GO:0016235)
0.0	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.2	GO:0034708	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	GO:0032009	early phagosome(GO:0032009)
0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.8	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.0	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.4	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	2.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	1.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.4	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.6	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID ARF 3PATHWAY	Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.4	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events

Results for HOXC12_HOXD12

Z-value: 0.96

Motif logo

Transcription factors associated with HOXC12_HOXD12

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXC12_HOXD12 motif across conditions

Conditions sorted by the z-value of the HOXC12_HOXD12 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: