Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HOXC9

Z-value: 1.99

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
ENSG00000180806.4 homeobox C9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_54394241_54394522HOXC94780.391807-0.206.0e-01Click!
chr12_54393897_54394133HOXC91120.617050-0.186.4e-01Click!
chr12_54396371_54396522HOXC925430.088604-0.137.4e-01Click!
chr12_54388856_54389199HOXC92660.421568-0.078.6e-01Click!
chr12_54394726_54394877HOXC98980.231338-0.039.3e-01Click!

Activity of the HOXC9 motif across conditions

Conditions sorted by the z-value of the HOXC9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_12598337_12598791 1.27 SPIRE1
spire-type actin nucleation factor 1
54520
0.09
chr2_64881941_64882849 1.09 SERTAD2
SERTA domain containing 2
1348
0.52
chr1_183776609_183776992 1.02 RGL1
ral guanine nucleotide dissociation stimulator-like 1
2510
0.36
chr1_31870163_31870721 0.96 SERINC2
serine incorporator 2
11970
0.15
chr8_78478320_78478688 0.93 ENSG00000222334
.
279452
0.02
chr12_29895057_29895338 0.92 TMTC1
transmembrane and tetratricopeptide repeat containing 1
41534
0.21
chr5_40401420_40402168 0.91 ENSG00000265615
.
81374
0.11
chr2_193011022_193011173 0.91 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
48153
0.19
chr1_67397953_67399117 0.90 MIER1
mesoderm induction early response 1, transcriptional regulator
2609
0.29
chr12_89339824_89340184 0.78 ENSG00000238302
.
336058
0.01
chr3_81789805_81790284 0.77 GBE1
glucan (1,4-alpha-), branching enzyme 1
2736
0.44
chr17_42872109_42872587 0.77 GJC1
gap junction protein, gamma 1, 45kDa
9986
0.14
chr1_167517405_167517629 0.74 CREG1
cellular repressor of E1A-stimulated genes 1
5487
0.22
chr3_172394693_172395213 0.74 ENSG00000264711
.
5524
0.18
chr4_40623166_40623743 0.74 RBM47
RNA binding motif protein 47
8427
0.27
chr5_115790516_115790946 0.73 CTB-118N6.3

5305
0.26
chr9_90215657_90216062 0.72 DAPK1-IT1
DAPK1 intronic transcript 1 (non-protein coding)
47490
0.16
chr12_64846967_64847658 0.71 TBK1
TANK-binding kinase 1
1057
0.53
chr6_88407042_88408017 0.70 AKIRIN2
akirin 2
4398
0.23
chr2_40612222_40612511 0.69 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
45054
0.2
chr21_40683413_40684326 0.69 BRWD1
bromodomain and WD repeat domain containing 1
1627
0.24
chr15_49336349_49337349 0.69 SECISBP2L
SECIS binding protein 2-like
1781
0.28
chr16_53809610_53810340 0.68 FTO
fat mass and obesity associated
71881
0.11
chr1_200333826_200333977 0.67 ZNF281
zinc finger protein 281
45219
0.19
chr2_161232105_161232912 0.67 ENSG00000252465
.
20971
0.19
chr6_114290051_114291212 0.67 RP3-399L15.3

234
0.87
chr3_189791102_189791307 0.66 ENSG00000265045
.
40519
0.14
chr22_19073574_19073725 0.66 AC004471.9

35393
0.09
chr10_99995580_99995731 0.64 RP11-34A14.3

16125
0.21
chr5_141320945_141321328 0.62 KIAA0141
KIAA0141
8171
0.13
chr4_54425031_54425364 0.61 LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
813
0.67
chr16_69255951_69256102 0.61 RP11-70O5.2

18426
0.12
chr9_116639997_116640288 0.60 ZNF618
zinc finger protein 618
1512
0.52
chr16_4103086_4103844 0.59 RP11-462G12.4

21452
0.2
chr1_172255657_172255977 0.59 ENSG00000252354
.
61466
0.11
chr10_17714984_17715727 0.59 ENSG00000251959
.
5832
0.17
chr2_28578659_28578961 0.59 FOSL2
FOS-like antigen 2
36859
0.13
chr5_39411390_39411705 0.59 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
13423
0.26
chr1_208115334_208115485 0.59 CD34
CD34 molecule
30662
0.24
chr9_80747244_80748140 0.58 ENSG00000222452
.
32689
0.22
chr13_42274733_42275224 0.58 ENSG00000241406
.
106835
0.07
chr6_125335196_125335438 0.57 RNF217
ring finger protein 217
30803
0.21
chr11_36387843_36388116 0.57 PRR5L
proline rich 5 like
4321
0.24
chr3_149290836_149290987 0.56 WWTR1
WW domain containing transcription regulator 1
3128
0.27
chr3_188994486_188994762 0.56 TPRG1-AS2
TPRG1 antisense RNA 2
36241
0.21
chr3_15834561_15835314 0.56 ANKRD28
ankyrin repeat domain 28
3091
0.28
chr7_116211652_116211947 0.56 AC006159.4

511
0.78
chr1_27626590_27626805 0.55 TMEM222
transmembrane protein 222
21954
0.11
chr8_130698164_130698381 0.55 GSDMC
gasdermin C
100862
0.07
chr7_41909334_41909592 0.55 AC005027.3

164530
0.04
chr4_57909352_57909761 0.55 ENSG00000251703
.
40698
0.11
chr13_21632728_21633071 0.55 LATS2
large tumor suppressor kinase 2
1530
0.35
chr8_8168819_8168970 0.55 ALG1L13P
asparagine-linked glycosylation 1-like 13, pseudogene
69961
0.09
chr2_153277819_153278036 0.55 FMNL2
formin-like 2
86176
0.1
chr8_57806614_57806867 0.55 ENSG00000206975
.
22903
0.26
chr3_187978157_187978521 0.55 LPP
LIM domain containing preferred translocation partner in lipoma
20687
0.25
chr7_111626824_111627073 0.54 DOCK4
dedicator of cytokinesis 4
17238
0.24
chr12_65700883_65701407 0.54 MSRB3
methionine sulfoxide reductase B3
19510
0.22
chr15_82422353_82422648 0.54 RP11-597K23.2
Uncharacterized protein
41468
0.14
chr2_178283039_178283431 0.54 AGPS
alkylglycerone phosphate synthase
25739
0.14
chr11_75657287_75657506 0.54 ENSG00000223013
.
11416
0.16
chr2_26232303_26232586 0.53 AC013449.1
Uncharacterized protein
19037
0.15
chr2_225010185_225010480 0.53 ENSG00000211987
.
93941
0.08
chr19_6103075_6103226 0.53 CTB-66B24.1

6183
0.15
chr10_30734331_30734677 0.53 MAP3K8
mitogen-activated protein kinase kinase kinase 8
6753
0.24
chr2_197264610_197264832 0.53 HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
37775
0.2
chr5_59397789_59398062 0.52 CTD-2254N19.1

71212
0.12
chr9_75764547_75765336 0.52 ANXA1
annexin A1
1732
0.5
chr9_127030175_127030580 0.52 RP11-121A14.3

5222
0.19
chr13_51163491_51163724 0.52 DLEU7-AS1
DLEU7 antisense RNA 1
218385
0.02
chr10_17827029_17827503 0.51 MRC1L1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
24096
0.17
chr1_161973787_161974282 0.51 OLFML2B
olfactomedin-like 2B
19012
0.22
chr1_68640359_68640547 0.51 ENSG00000221203
.
8840
0.22
chr11_15128125_15128276 0.51 INSC
inscuteable homolog (Drosophila)
5770
0.28
chr16_81638343_81638641 0.51 CMIP
c-Maf inducing protein
40471
0.2
chr2_226983987_226984250 0.51 ENSG00000263363
.
539391
0.0
chr1_114520883_114521106 0.50 OLFML3
olfactomedin-like 3
1069
0.49
chr3_188139152_188139752 0.50 LPP-AS1
LPP antisense RNA 1
147002
0.04
chr2_33467839_33468340 0.50 LTBP1
latent transforming growth factor beta binding protein 1
640
0.79
chr3_182992678_182993398 0.50 B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
9906
0.2
chr11_34449252_34449782 0.50 CAT
catalase
10955
0.23
chr22_18539461_18539695 0.50 XXbac-B476C20.9

20985
0.13
chr3_142719040_142719191 0.50 U2SURP
U2 snRNP-associated SURP domain containing
1251
0.46
chr15_77713627_77714545 0.50 HMG20A
high mobility group 20A
733
0.64
chr4_48256106_48256549 0.50 TEC
tec protein tyrosine kinase
15554
0.23
chr16_27590290_27590441 0.49 KIAA0556
KIAA0556
5137
0.22
chr20_5705538_5705977 0.49 C20orf196
chromosome 20 open reading frame 196
25282
0.23
chr6_140892392_140892543 0.49 ENSG00000221336
.
89383
0.1
chr17_60074998_60075962 0.49 ENSG00000242398
.
7868
0.17
chr18_53177775_53178126 0.49 TCF4
transcription factor 4
50
0.98
chr21_40361446_40361610 0.49 ENSG00000272015
.
94819
0.08
chr18_46355342_46355813 0.49 RP11-484L8.1

5564
0.29
chr3_149088815_149089173 0.49 TM4SF1
transmembrane 4 L six family member 1
4505
0.2
chr8_123122166_123122317 0.48 HAS2-AS1
HAS2 antisense RNA 1
468565
0.01
chr5_14439490_14439641 0.48 TRIO
trio Rho guanine nucleotide exchange factor
48992
0.18
chr9_81313324_81313640 0.48 PSAT1
phosphoserine aminotransferase 1
401423
0.01
chr15_81631153_81631419 0.48 RP11-761I4.3

2703
0.27
chr5_14400569_14400746 0.48 TRIO
trio Rho guanine nucleotide exchange factor
87900
0.1
chr5_80922589_80922740 0.48 SSBP2
single-stranded DNA binding protein 2
113128
0.07
chr22_37908842_37909144 0.48 CARD10
caspase recruitment domain family, member 10
745
0.57
chr13_73354563_73355562 0.48 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
1001
0.39
chr13_40684091_40684242 0.48 ENSG00000207458
.
116798
0.07
chr16_53246810_53247380 0.48 CHD9
chromodomain helicase DNA binding protein 9
4732
0.24
chr13_33853268_33853419 0.48 ENSG00000236581
.
1653
0.41
chr1_178244577_178244818 0.48 RASAL2
RAS protein activator like 2
65909
0.14
chr1_61607422_61607671 0.48 RP4-802A10.1

17141
0.23
chr18_3454886_3455393 0.48 TGIF1
TGFB-induced factor homeobox 1
11
0.98
chr18_52995287_52995506 0.48 TCF4
transcription factor 4
5871
0.31
chr12_26303323_26303715 0.47 SSPN
sarcospan
15619
0.18
chr3_136505593_136506225 0.47 SLC35G2
solute carrier family 35, member G2
31952
0.12
chr16_85084815_85085194 0.47 KIAA0513
KIAA0513
11814
0.21
chr12_6198255_6198797 0.47 ENSG00000240533
.
6610
0.23
chr2_159947065_159947542 0.47 ENSG00000202029
.
63649
0.13
chr11_103396303_103396486 0.47 DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
167423
0.04
chr17_53804938_53805089 0.47 TMEM100
transmembrane protein 100
4469
0.29
chr6_86155572_86155723 0.47 NT5E
5'-nucleotidase, ecto (CD73)
4162
0.33
chr7_82224652_82224988 0.47 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
151706
0.05
chr14_23775130_23775401 0.47 BCL2L2
BCL2-like 2
706
0.31
chr11_112027840_112028079 0.47 IL18
interleukin 18 (interferon-gamma-inducing factor)
6838
0.11
chr10_62186857_62187008 0.46 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
37444
0.23
chr22_32267281_32267544 0.46 DEPDC5
DEP domain containing 5
18510
0.16
chr4_160113629_160113918 0.46 ENSG00000264105
.
63727
0.11
chr11_116784063_116784557 0.46 SIK3-IT1
SIK3 intronic transcript 1 (non-protein coding)
22873
0.14
chr9_124033827_124034080 0.46 GSN
gelsolin
3573
0.18
chr6_22026198_22026944 0.46 ENSG00000222515
.
59202
0.17
chr12_91290582_91290865 0.46 CCER1
coiled-coil glutamate-rich protein 1
58230
0.15
chr8_69646501_69646652 0.46 ENSG00000239184
.
38698
0.22
chr9_81321983_81322311 0.46 PSAT1
phosphoserine aminotransferase 1
410088
0.01
chr6_133033571_133033918 0.46 VNN1
vanin 1
1444
0.34
chr8_123147466_123147695 0.46 HAS2-AS1
HAS2 antisense RNA 1
493904
0.0
chr2_40328493_40328783 0.45 SLC8A1-AS1
SLC8A1 antisense RNA 1
3411
0.39
chr1_97610616_97610767 0.45 DPYD-AS1
DPYD antisense RNA 1
49212
0.19
chr15_59462353_59462672 0.45 ENSG00000253030
.
949
0.42
chr3_156506429_156506580 0.45 LEKR1
leucine, glutamate and lysine rich 1
37585
0.2
chr11_9587986_9588266 0.45 WEE1
WEE1 G2 checkpoint kinase
7102
0.16
chr3_172036360_172036556 0.45 AC092964.1
Uncharacterized protein
2240
0.34
chr12_10344371_10344522 0.45 TMEM52B
transmembrane protein 52B
12333
0.12
chr16_19129843_19130268 0.45 RP11-626G11.3

2896
0.21
chr16_69510453_69510859 0.45 CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
51970
0.1
chr2_208121057_208121376 0.45 AC007879.5

2240
0.34
chr20_58563521_58563805 0.45 CDH26
cadherin 26
498
0.81
chr22_24798801_24798960 0.45 ADORA2A
adenosine A2a receptor
20685
0.18
chr7_75164072_75164427 0.45 PMS2P3
postmeiotic segregation increased 2 pseudogene 3
7110
0.15
chr7_93690848_93690999 0.45 BET1
Bet1 golgi vesicular membrane trafficking protein
57229
0.14
chr17_35974821_35975108 0.45 RP11-697E22.1

5177
0.17
chr9_79075654_79076239 0.45 GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
1800
0.46
chr17_57846998_57847149 0.45 VMP1
vacuole membrane protein 1
4042
0.2
chr10_126846033_126846605 0.45 CTBP2
C-terminal binding protein 2
966
0.69
chr5_77798034_77798185 0.45 LHFPL2
lipoma HMGIC fusion partner-like 2
46865
0.18
chr2_164207451_164207602 0.44 ENSG00000200902
.
62021
0.16
chr7_101584838_101585234 0.44 CTB-181H17.1

18360
0.23
chr8_96714411_96714562 0.44 ENSG00000223297
.
23343
0.26
chr17_71303101_71303370 0.44 CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
4312
0.22
chr5_52655252_52655542 0.44 FST
follistatin
120842
0.06
chr4_79705695_79705981 0.44 BMP2K
BMP2 inducible kinase
8306
0.19
chr10_75726148_75726415 0.44 VCL
vinculin
31591
0.12
chr7_116712734_116712923 0.44 ST7-AS2
ST7 antisense RNA 2
1950
0.33
chr12_13247017_13247257 0.44 GSG1
germ cell associated 1
1445
0.43
chr6_52425530_52425681 0.44 TRAM2
translocation associated membrane protein 2
16108
0.24
chr8_25032357_25032508 0.44 ENSG00000241811
.
6803
0.25
chr22_37908037_37908429 0.44 CARD10
caspase recruitment domain family, member 10
15
0.97
chr5_127294983_127295134 0.44 SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
124400
0.06
chr14_103480838_103481545 0.44 CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
42608
0.12
chr4_48332474_48332625 0.44 SLAIN2
SLAIN motif family, member 2
10790
0.24
chr1_59231029_59231230 0.43 ENSG00000264081
.
522
0.8
chr3_32185972_32186147 0.43 ENSG00000238646
.
28089
0.16
chr15_68406407_68406736 0.43 PIAS1
protein inhibitor of activated STAT, 1
59657
0.12
chr1_26187643_26188072 0.43 RP1-125I3.2

1753
0.17
chr18_9731207_9731358 0.43 RAB31
RAB31, member RAS oncogene family
23120
0.2
chr11_33712841_33713004 0.43 RP4-541C22.5

5325
0.18
chr1_64638258_64638590 0.43 RP11-24J23.2

1444
0.46
chr5_81702467_81702618 0.43 ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
101376
0.08
chr4_139327101_139327252 0.43 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
163673
0.04
chr15_86016825_86017700 0.43 AKAP13
A kinase (PRKA) anchor protein 13
70009
0.09
chr4_48727990_48728340 0.43 FRYL
FRY-like
44977
0.16
chr4_169526190_169526341 0.43 PALLD
palladin, cytoskeletal associated protein
26501
0.19
chr5_81460698_81461288 0.43 ENSG00000265684
.
86747
0.08
chr11_78509149_78509300 0.43 TENM4
teneurin transmembrane protein 4
7232
0.27
chr2_163101483_163101634 0.43 FAP
fibroblast activation protein, alpha
1513
0.46
chr4_170146180_170146331 0.42 RP11-327O17.2

23310
0.22
chr20_52354290_52354570 0.42 ENSG00000238468
.
69133
0.12
chr7_47541782_47542068 0.42 TNS3
tensin 3
21042
0.28
chr6_56820926_56821126 0.42 BEND6
BEN domain containing 6
856
0.52
chr1_206846612_206846999 0.42 ENSG00000252853
.
8503
0.14
chr14_53268642_53268793 0.42 GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
10331
0.16
chr6_114018570_114018876 0.42 ENSG00000221559
.
7312
0.27
chr7_41465174_41465470 0.42 INHBA-AS1
INHBA antisense RNA 1
268192
0.02
chr8_8483741_8483892 0.42 ENSG00000264445
.
7158
0.25
chr20_10521233_10521444 0.42 SLX4IP
SLX4 interacting protein
105387
0.06
chr15_45881879_45882313 0.42 BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
2073
0.2
chr1_109912007_109912390 0.42 SORT1
sortilin 1
23781
0.14
chr1_39624769_39624920 0.42 ENSG00000222378
.
4876
0.2
chr7_101596544_101596695 0.42 CTB-181H17.1

6777
0.27
chr15_71006405_71006665 0.42 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
10921
0.26
chr6_134744399_134744550 0.42 SGK1
serum/glucocorticoid regulated kinase 1
105224
0.07
chr1_87239226_87239594 0.42 SH3GLB1
SH3-domain GRB2-like endophilin B1
68832
0.09
chr3_194041385_194041965 0.41 CPN2
carboxypeptidase N, polypeptide 2
30372
0.17
chr2_86644875_86645090 0.41 KDM3A
lysine (K)-specific demethylase 3A
22788
0.17
chr10_126835454_126835747 0.41 CTBP2
C-terminal binding protein 2
11685
0.28
chr1_109938801_109939938 0.41 SORT1
sortilin 1
1204
0.42

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.3 0.8 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.6 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2 1.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 0.5 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2 0.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.8 GO:0071221 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.2 0.6 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.8 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.5 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.5 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.6 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.7 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.1 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.4 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0071436 sodium ion export(GO:0071436)
0.1 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.7 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.4 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.6 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.2 GO:0032898 neurotrophin production(GO:0032898)
0.1 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.1 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.2 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.4 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.3 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.5 GO:0015871 choline transport(GO:0015871)
0.1 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.2 GO:0006573 valine metabolic process(GO:0006573)
0.1 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.1 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.6 GO:0048844 artery morphogenesis(GO:0048844)
0.1 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.1 GO:0060437 lung growth(GO:0060437)
0.1 0.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 0.3 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0070254 mucus secretion(GO:0070254)
0.1 0.5 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.7 GO:0035329 hippo signaling(GO:0035329)
0.1 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.2 GO:0018101 protein citrullination(GO:0018101)
0.1 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 0.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.2 GO:0042640 anagen(GO:0042640)
0.1 0.1 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.1 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.7 GO:0032964 collagen biosynthetic process(GO:0032964)
0.1 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.3 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.1 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0051133 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.0 0.1 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.2 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.6 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0035067 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0048541 Peyer's patch development(GO:0048541)
0.0 0.2 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.5 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:1901222 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.5 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.3 GO:0019048 modulation by virus of host morphology or physiology(GO:0019048)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.0 GO:0060405 regulation of penile erection(GO:0060405)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.0 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.0 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.0 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0014075 response to amine(GO:0014075)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0021930 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.0 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.2 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.0 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.0 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0052803 imidazole-containing compound metabolic process(GO:0052803)
0.0 0.1 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0042363 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0035315 hair cell differentiation(GO:0035315)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032449 CBM complex(GO:0032449)
0.2 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.6 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0071437 invadopodium(GO:0071437)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 1.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.6 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.9 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 1.1 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.1 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470)
0.1 0.4 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.4 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.4 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0015368 calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.7 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0019199 transmembrane receptor protein kinase activity(GO:0019199)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.5 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.2 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease