Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HSF1

Z-value: 2.45

Motif logo

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Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.6 HSF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HSF1chr8_145526786_14552693757300.0865220.752.0e-02Click!
HSF1chr8_145515810_1455163591780.8425430.742.4e-02Click!
HSF1chr8_145516707_1455169245530.5338520.646.6e-02Click!
HSF1chr8_145518993_14551914428060.1179910.422.7e-01Click!
HSF1chr8_145517605_14551775614180.2105480.383.1e-01Click!

Activity of the HSF1 motif across conditions

Conditions sorted by the z-value of the HSF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_29675395_29675762 1.28 QPRT
quinolinate phosphoribosyltransferase
978
0.33
chr11_117821389_117821783 0.87 TMPRSS13
transmembrane protease, serine 13
21412
0.15
chr14_104861166_104861551 0.85 ENSG00000222761
.
6027
0.28
chr12_107764032_107764308 0.83 ENSG00000200897
.
4354
0.29
chr14_99670994_99671151 0.79 AL162151.4

46319
0.15
chr1_151131578_151131836 0.78 SCNM1
sodium channel modifier 1
2567
0.12
chrX_48771547_48771831 0.77 PIM2
pim-2 oncogene
1323
0.25
chr1_167059213_167059701 0.77 GPA33
glycoprotein A33 (transmembrane)
411
0.81
chr9_130784552_130784902 0.77 RP11-379C10.1

34914
0.08
chr2_233950353_233950744 0.74 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
25359
0.17
chr3_177269440_177269746 0.69 ENSG00000252028
.
48253
0.18
chr16_3838912_3839326 0.68 CREBBP
CREB binding protein
8251
0.23
chr14_101106211_101106459 0.67 CTD-2644I21.1

50672
0.08
chr7_2739468_2739742 0.67 AMZ1
archaelysin family metallopeptidase 1
11769
0.21
chr1_27682575_27682843 0.66 MAP3K6
mitogen-activated protein kinase kinase kinase 6
253
0.87
chr17_8858301_8858611 0.65 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
10568
0.24
chr17_7456942_7457093 0.64 TNFSF12
tumor necrosis factor (ligand) superfamily, member 12
4546
0.06
chr7_150211133_150211430 0.63 GIMAP7
GTPase, IMAP family member 7
637
0.73
chr19_4303888_4304210 0.62 FSD1
fibronectin type III and SPRY domain containing 1
548
0.54
chr9_136542992_136543196 0.62 DBH-AS1
DBH antisense RNA 1
20659
0.14
chr2_231737266_231737417 0.62 ITM2C
integral membrane protein 2C
6962
0.18
chr11_73680841_73681161 0.62 RP11-167N4.2

331
0.84
chr21_36340846_36341061 0.61 RUNX1
runt-related transcription factor 1
78866
0.12
chr1_100856884_100857083 0.61 ENSG00000216067
.
12652
0.2
chr22_37518928_37519269 0.61 TMPRSS6
transmembrane protease, serine 6
13495
0.11
chr2_217218636_217218797 0.61 ENSG00000207303
.
2590
0.25
chr5_175968029_175968264 0.60 CDHR2
cadherin-related family member 2
1366
0.29
chr15_38979216_38979456 0.60 C15orf53
chromosome 15 open reading frame 53
9463
0.29
chr20_2722949_2723333 0.60 EBF4
early B-cell factor 4
36254
0.09
chr7_139312464_139312655 0.60 CLEC2L
C-type lectin domain family 2, member L
103731
0.06
chr10_45917176_45917536 0.60 RP11-67C2.2

31213
0.18
chr22_40729451_40729738 0.60 ADSL
adenylosuccinate lyase
12913
0.18
chr3_31504876_31505139 0.59 ENSG00000238727
.
67578
0.12
chr3_46394034_46394455 0.59 CCR2
chemokine (C-C motif) receptor 2
981
0.53
chr17_72752966_72753168 0.58 SLC9A3R1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
5075
0.11
chr9_92026891_92027195 0.58 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
6202
0.26
chr8_59930806_59931005 0.58 RP11-328K2.1

25408
0.23
chr5_75622593_75622811 0.58 RP11-466P24.6

15415
0.26
chr22_27039164_27039368 0.57 CRYBA4
crystallin, beta A4
21338
0.17
chr3_183233385_183233617 0.57 KLHL6-AS1
KLHL6 antisense RNA 1
33022
0.11
chr8_91027854_91028058 0.57 DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
14211
0.21
chr17_75842366_75842622 0.57 FLJ45079

36165
0.19
chr1_9486021_9486424 0.57 ENSG00000252956
.
11615
0.23
chr15_75136605_75137116 0.56 ULK3
unc-51 like kinase 3
1322
0.29
chr1_28525263_28525593 0.56 AL353354.2

1642
0.2
chr14_104858355_104858716 0.56 ENSG00000222761
.
8850
0.27
chr16_68453137_68453288 0.56 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
29183
0.12
chr11_117871694_117871911 0.56 IL10RA
interleukin 10 receptor, alpha
14693
0.17
chr7_76984643_76984884 0.55 GSAP
gamma-secretase activating protein
25079
0.21
chr2_111610099_111610292 0.55 ACOXL
acyl-CoA oxidase-like
47299
0.19
chrX_135226872_135227074 0.55 FHL1
four and a half LIM domains 1
2586
0.3
chr1_206734639_206734815 0.55 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
4234
0.2
chr3_13052264_13052559 0.55 IQSEC1
IQ motif and Sec7 domain 1
23875
0.24
chr21_45575872_45576023 0.55 AP001055.1

17633
0.13
chr6_159139178_159139369 0.55 ENSG00000265558
.
46512
0.12
chr1_185250977_185251218 0.54 ENSG00000252612
.
15430
0.16
chr14_90426118_90426635 0.54 TDP1
tyrosyl-DNA phosphodiesterase 1
1739
0.4
chr14_98440597_98440771 0.54 C14orf64
chromosome 14 open reading frame 64
3699
0.39
chr14_69239916_69240125 0.54 ZFP36L1
ZFP36 ring finger protein-like 1
17940
0.2
chr2_233933362_233933617 0.54 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
8300
0.19
chr15_26056534_26056770 0.54 ENSG00000199214
.
6478
0.21
chr1_779209_779379 0.54 RP11-206L10.8

33753
0.1
chrX_118888447_118888648 0.54 SOWAHD
sosondowah ankyrin repeat domain family member D
4029
0.19
chr17_33849169_33849564 0.53 RP11-1094M14.5

12077
0.11
chr1_194259597_194259842 0.53 ENSG00000251813
.
197616
0.03
chr1_209931882_209932204 0.53 TRAF3IP3
TRAF3 interacting protein 3
200
0.92
chr5_39212456_39212665 0.53 FYB
FYN binding protein
7105
0.3
chr13_114912317_114912766 0.53 RASA3
RAS p21 protein activator 3
14455
0.21
chr21_44103381_44103532 0.53 PDE9A
phosphodiesterase 9A
29533
0.15
chr2_85055860_85056021 0.53 TRABD2A
TraB domain containing 2A
52266
0.12
chr3_15709764_15709915 0.53 ENSG00000264354
.
29039
0.15
chr2_65046448_65046766 0.53 ENSG00000239891
.
2095
0.31
chr7_130596773_130597211 0.53 ENSG00000226380
.
34694
0.19
chr1_118197732_118198071 0.53 ENSG00000212266
.
33463
0.17
chr19_42276662_42276849 0.53 AC011513.4

14046
0.12
chr16_50303522_50303851 0.52 ADCY7
adenylate cyclase 7
3224
0.27
chr1_154376165_154376624 0.52 IL6R
interleukin 6 receptor
1275
0.33
chr2_85072974_85073263 0.52 TRABD2A
TraB domain containing 2A
35088
0.16
chr9_101839301_101839643 0.52 TGFBR1
transforming growth factor, beta receptor 1
26848
0.2
chr3_32498174_32498359 0.52 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
46634
0.14
chr1_202131748_202132038 0.52 PTPN7
protein tyrosine phosphatase, non-receptor type 7
1177
0.39
chr6_167507061_167507399 0.52 CCR6
chemokine (C-C motif) receptor 6
18065
0.18
chr7_149565914_149566574 0.52 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
3813
0.19
chr8_22023106_22023363 0.51 BMP1
bone morphogenetic protein 1
434
0.71
chr10_7201395_7201546 0.51 SFMBT2
Scm-like with four mbt domains 2
249237
0.02
chr16_68105212_68105363 0.51 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
13960
0.09
chr2_12268194_12268483 0.51 ENSG00000264089
.
70918
0.12
chr3_48519266_48519585 0.51 SHISA5
shisa family member 5
4808
0.1
chrX_135846152_135846303 0.51 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
3275
0.24
chr6_137674077_137674372 0.51 IFNGR1
interferon gamma receptor 1
133638
0.05
chr10_14702537_14702914 0.51 ENSG00000201766
.
2768
0.28
chr1_25421803_25422058 0.51 ENSG00000264371
.
71936
0.09
chr5_75627862_75628101 0.51 RP11-466P24.6

20694
0.25
chr7_3080892_3081043 0.51 CARD11
caspase recruitment domain family, member 11
2512
0.35
chr14_71112294_71112797 0.51 TTC9
tetratricopeptide repeat domain 9
4041
0.25
chr15_30471500_30471800 0.51 ENSG00000221785
.
34570
0.11
chr17_38756509_38756660 0.50 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
31958
0.11
chr19_16473682_16473998 0.50 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
1076
0.45
chr18_74828060_74828346 0.50 MBP
myelin basic protein
10986
0.29
chr1_6523227_6523383 0.50 TNFRSF25
tumor necrosis factor receptor superfamily, member 25
2385
0.17
chr20_37503628_37504045 0.50 ENSG00000240474
.
2423
0.3
chr15_85142182_85142412 0.50 ZSCAN2
zinc finger and SCAN domain containing 2
1920
0.21
chr5_133425812_133426164 0.50 TCF7
transcription factor 7 (T-cell specific, HMG-box)
24414
0.2
chr15_38959821_38960153 0.50 C15orf53
chromosome 15 open reading frame 53
28812
0.22
chr14_99667002_99667153 0.50 AL162151.4

42324
0.16
chr22_39491051_39491450 0.50 APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
1979
0.23
chr11_61520539_61520749 0.50 MYRF
myelin regulatory factor
523
0.7
chr15_32651213_32651761 0.50 ENSG00000221444
.
34186
0.1
chr4_153020620_153020907 0.49 ENSG00000253077
.
127998
0.05
chr14_23035018_23035185 0.49 AE000662.93

9145
0.11
chr12_47758069_47758220 0.49 ENSG00000264906
.
92
0.98
chr1_25350610_25350934 0.49 ENSG00000264371
.
778
0.7
chrX_19764292_19764574 0.49 SH3KBP1
SH3-domain kinase binding protein 1
96
0.98
chr10_74045426_74045721 0.49 RP11-442H21.2

9835
0.16
chr2_128397004_128397315 0.49 LIMS2
LIM and senescent cell antigen-like domains 2
2547
0.21
chr21_43842986_43843137 0.49 ENSG00000252619
.
5359
0.15
chr2_149298526_149298681 0.48 MBD5
methyl-CpG binding domain protein 5
72309
0.12
chr12_22313183_22313433 0.48 ENSG00000212172
.
35255
0.2
chr3_134013773_134013924 0.48 RYK
receptor-like tyrosine kinase
44159
0.16
chr20_42697519_42697810 0.48 TOX2
TOX high mobility group box family member 2
14673
0.22
chr1_9789105_9789546 0.48 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
11198
0.17
chr12_68025335_68025706 0.48 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
16598
0.25
chr9_134139828_134140044 0.48 FAM78A
family with sequence similarity 78, member A
5944
0.19
chr17_63025333_63025500 0.48 RP11-583F2.5

22611
0.15
chr22_40316109_40316336 0.48 GRAP2
GRB2-related adaptor protein 2
6373
0.19
chr14_61898261_61898412 0.48 PRKCH
protein kinase C, eta
10940
0.25
chr22_40339084_40339238 0.48 GRAP2
GRB2-related adaptor protein 2
3660
0.21
chr1_167598142_167598391 0.47 RCSD1
RCSD domain containing 1
1064
0.46
chr17_33503898_33504049 0.47 RP11-799D4.3

9942
0.11
chr17_47837882_47838168 0.47 FAM117A
family with sequence similarity 117, member A
3468
0.2
chr8_27235111_27235488 0.47 PTK2B
protein tyrosine kinase 2 beta
2869
0.31
chr15_64184347_64184498 0.47 ENSG00000199156
.
21204
0.19
chr5_133426970_133427238 0.47 TCF7
transcription factor 7 (T-cell specific, HMG-box)
23298
0.2
chr8_82006436_82006760 0.47 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
17705
0.27
chr17_40574094_40574415 0.47 PTRF
polymerase I and transcript release factor
1281
0.3
chr20_58639264_58639415 0.47 C20orf197
chromosome 20 open reading frame 197
8359
0.26
chr6_41169070_41169540 0.46 TREML2
triggering receptor expressed on myeloid cells-like 2
373
0.8
chr9_101854604_101854935 0.46 TGFBR1
transforming growth factor, beta receptor 1
11551
0.23
chr6_33873520_33874114 0.46 ENSG00000221697
.
94011
0.06
chr1_24851023_24851224 0.46 ENSG00000266551
.
5081
0.18
chr9_139855211_139855362 0.46 LCN12
lipocalin 12
7858
0.06
chr17_45919562_45919713 0.46 SCRN2
secernin 2
938
0.4
chr9_82498334_82498832 0.46 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
176902
0.04
chr2_54226465_54226799 0.46 ACYP2
acylphosphatase 2, muscle type
28387
0.17
chr2_85122249_85122728 0.46 AC022210.1

143
0.96
chr2_97260504_97260755 0.46 KANSL3
KAT8 regulatory NSL complex subunit 3
43417
0.13
chr8_37134401_37134693 0.46 RP11-150O12.6

239992
0.02
chr4_154449092_154449243 0.46 KIAA0922
KIAA0922
27881
0.22
chr16_85481767_85482285 0.46 ENSG00000264203
.
6928
0.27
chr1_183447249_183447596 0.46 SMG7
SMG7 nonsense mediated mRNA decay factor
5355
0.23
chr14_91849387_91849607 0.46 CCDC88C
coiled-coil domain containing 88C
34193
0.17
chr8_97293366_97293578 0.46 PTDSS1
phosphatidylserine synthase 1
13948
0.16
chr12_15116052_15116331 0.46 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
1529
0.36
chr16_27462069_27462270 0.46 IL21R-AS1
IL21R antisense RNA 1
2545
0.28
chr17_46521887_46522400 0.46 SKAP1
src kinase associated phosphoprotein 1
14562
0.13
chr17_73818533_73818684 0.46 RP11-552F3.4

2472
0.13
chr1_160807961_160808535 0.45 LY9
lymphocyte antigen 9
23935
0.13
chr12_133410838_133411057 0.45 ENSG00000252079
.
1139
0.41
chr6_139644195_139644440 0.45 TXLNB
taxilin beta
31041
0.17
chr19_3757648_3757799 0.45 AC005954.3

1066
0.31
chr16_4726555_4727017 0.45 NUDT16L1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
16909
0.11
chr18_72045784_72046068 0.45 C18orf63
chromosome 18 open reading frame 63
62878
0.11
chr18_74832353_74832701 0.45 MBP
myelin basic protein
7141
0.31
chr3_15319262_15319413 0.45 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
1785
0.29
chr19_4084516_4084732 0.45 MAP2K2
mitogen-activated protein kinase kinase 2
16421
0.11
chr3_36918303_36918662 0.45 TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
18108
0.23
chr1_169662886_169663277 0.45 SELL
selectin L
17758
0.18
chr8_42000592_42000772 0.45 RP11-589C21.5

9599
0.17
chr2_158288303_158288454 0.45 CYTIP
cytohesin 1 interacting protein
7548
0.23
chr14_106559958_106560328 0.45 IGHV2-10
immunoglobulin heavy variable 2-10 (pseudogene)
168
0.82
chr21_45774588_45774760 0.45 TRPM2
transient receptor potential cation channel, subfamily M, member 2
1103
0.32
chr7_5819044_5819195 0.45 RNF216
ring finger protein 216
2132
0.31
chr5_133879414_133879576 0.45 JADE2
jade family PHD finger 2
17168
0.15
chr1_239884614_239884789 0.45 CHRM3
cholinergic receptor, muscarinic 3
1858
0.37
chr14_22985554_22985705 0.45 TRAJ15
T cell receptor alpha joining 15
12951
0.1
chr15_29135573_29135724 0.45 APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
4339
0.25
chr3_33058315_33058653 0.45 CCR4
chemokine (C-C motif) receptor 4
65418
0.1
chr19_55020227_55020521 0.44 LAIR2
leukocyte-associated immunoglobulin-like receptor 2
6251
0.11
chr18_23646752_23646903 0.44 SS18
synovial sarcoma translocation, chromosome 18
23233
0.24
chr2_131799521_131799672 0.44 ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
746
0.7
chr5_54399188_54399417 0.44 GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
826
0.55
chr1_167425889_167426196 0.44 RP11-104L21.2

1856
0.39
chr6_108111162_108111313 0.44 SCML4
sex comb on midleg-like 4 (Drosophila)
17782
0.26
chr16_79446696_79446975 0.44 ENSG00000222244
.
148484
0.04
chr11_14460647_14460848 0.44 ENSG00000251991
.
39691
0.16
chr14_23012176_23012454 0.44 AE000662.92
Uncharacterized protein
13219
0.1
chrX_1695042_1695324 0.44 AKAP17A
A kinase (PRKA) anchor protein 17A
15303
0.19
chrY_1645043_1645322 0.44 NA
NA
> 106
NA
chrX_129222828_129223069 0.44 ELF4
E74-like factor 4 (ets domain transcription factor)
21388
0.19
chr11_104580093_104580269 0.44 CASP12
caspase 12 (gene/pseudogene)
188960
0.03
chr3_107695096_107695544 0.44 CD47
CD47 molecule
81888
0.11
chr20_57722445_57722676 0.44 ZNF831
zinc finger protein 831
43515
0.15
chr14_64204314_64204465 0.44 ENSG00000252749
.
1227
0.46
chr8_19269628_19269895 0.44 SH2D4A
SH2 domain containing 4A
92660
0.09
chr9_95765161_95765312 0.44 FGD3
FYVE, RhoGEF and PH domain containing 3
12106
0.2
chr22_40311562_40311713 0.43 GRAP2
GRB2-related adaptor protein 2
10958
0.17
chr13_99993452_99993845 0.43 ENSG00000207719
.
14737
0.19
chr2_7063081_7063289 0.43 ENSG00000228203
.
4345
0.21
chr3_31506056_31506507 0.43 STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
68001
0.12
chr10_74023657_74023857 0.43 DDIT4
DNA-damage-inducible transcript 4
9921
0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.5 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.2 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 0.7 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.2 1.3 GO:0007172 signal complex assembly(GO:0007172)
0.2 1.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 0.5 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.2 0.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 1.9 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 0.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.5 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.1 0.4 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.3 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.5 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.1 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 0.4 GO:2000351 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.3 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1 0.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.5 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.4 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.3 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.3 GO:0017085 response to insecticide(GO:0017085)
0.1 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.3 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.1 GO:0002724 regulation of T cell cytokine production(GO:0002724)
0.1 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.2 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1 0.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.6 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.1 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.1 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.3 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.1 GO:0071503 response to heparin(GO:0071503)
0.1 0.1 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.1 0.3 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.3 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.3 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.2 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.1 GO:0002874 chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.3 GO:0044068 modulation by virus of host process(GO:0019054) modulation by symbiont of host cellular process(GO:0044068)
0.1 0.6 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.1 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.1 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.1 GO:0010535 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.2 GO:0090192 regulation of glomerulus development(GO:0090192)
0.1 0.1 GO:1903309 negative regulation of chromatin modification(GO:1903309)
0.1 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.5 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.1 0.7 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.1 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.2 GO:0070295 renal water absorption(GO:0070295)
0.1 0.2 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1 0.7 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.1 0.6 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.1 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.3 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.1 0.2 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 0.4 GO:0002418 immune response to tumor cell(GO:0002418)
0.1 0.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 0.2 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.3 GO:0060263 regulation of respiratory burst(GO:0060263)
0.1 0.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.1 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.1 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0000303 response to superoxide(GO:0000303)
0.1 0.9 GO:1903311 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.1 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.2 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.2 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.6 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.1 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 1.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 0.1 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546)
0.1 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.3 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.2 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.2 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.2 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.2 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.5 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0032645 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.0 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.4 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.7 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0003171 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 1.2 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0021853 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.0 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.2 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0042506 tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0032106 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.2 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.2 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.2 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239)
0.0 0.1 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 0.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0006266 DNA ligation(GO:0006266)
0.0 0.5 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0021612 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.2 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.0 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.3 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0014888 striated muscle adaptation(GO:0014888)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 1.3 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0043526 obsolete neuroprotection(GO:0043526)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.0 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.0 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.6 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0006997 nucleus organization(GO:0006997)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.0 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.0 GO:0022406 membrane docking(GO:0022406)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.0 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.1 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.3 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.1 GO:1902808 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.0 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.3 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:1901799 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0090322 regulation of superoxide anion generation(GO:0032928) regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.0 0.0 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.7 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.0 0.0 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.6 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.4 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.0 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.1 GO:1902583 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response(GO:0002381)
0.0 0.1 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557) membrane biogenesis(GO:0044091)
0.0 0.3 GO:0042384 cilium assembly(GO:0042384)
0.0 0.1 GO:1903076 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.0 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.0 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 1.9 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.0 0.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.4 GO:0007498 mesoderm development(GO:0007498)
0.0 0.0 GO:0046688 response to copper ion(GO:0046688)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0044036 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.6 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0071333 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.0 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.0 GO:0046477 glycosylceramide metabolic process(GO:0006677) glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.7 GO:0009615 response to virus(GO:0009615)
0.0 0.0 GO:0016458 gene silencing(GO:0016458)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0033233 regulation of protein sumoylation(GO:0033233)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0042098 T cell proliferation(GO:0042098)
0.0 0.0 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.8 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.9 GO:0043218 compact myelin(GO:0043218)
0.2 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.3 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.5 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0031904 endosome lumen(GO:0031904)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.3 GO:0045179 apical cortex(GO:0045179)
0.1 0.2 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.1 0.1 GO:0001740 Barr body(GO:0001740)
0.1 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0070603 SWI/SNF superfamily-type complex(GO:0070603)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.0 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 1.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0005680 nuclear ubiquitin ligase complex(GO:0000152) anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 1.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0097525 spliceosomal snRNP complex(GO:0097525)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.0 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 1.5 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.4 GO:0005768 endosome(GO:0005768)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.0 GO:0044815 DNA packaging complex(GO:0044815)
0.0 2.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.0 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.0 0.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.4 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.2 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0070061 fructose binding(GO:0070061)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.0 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.8 GO:0016830 carbon-carbon lyase activity(GO:0016830)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 2.6 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.0 GO:0033265 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.5 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0016410 N-acyltransferase activity(GO:0016410)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0042625 ATPase coupled ion transmembrane transporter activity(GO:0042625)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 2.3 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 6.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 0.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 2.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.6 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.1 1.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.0 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS