Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HSF2

Z-value: 0.61

Motif logo

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
ENSG00000025156.8 HSF2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HSF2chr6_122725724_12272587551030.2893790.844.5e-03Click!
HSF2chr6_122733810_12273396194160.2546510.818.6e-03Click!
HSF2chr6_122721794_12272201212070.5895890.781.4e-02Click!
HSF2chr6_122722453_12272260418320.4526370.771.6e-02Click!
HSF2chr6_122724067_12272421834460.3264100.742.2e-02Click!

Activity of the HSF2 motif across conditions

Conditions sorted by the z-value of the HSF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_29289116_29289267 0.32 ENSG00000206704
.
23031
0.18
chr14_99670994_99671151 0.24 AL162151.4

46319
0.15
chr2_95741879_95742163 0.21 AC103563.9

23100
0.15
chr5_133426970_133427238 0.19 TCF7
transcription factor 7 (T-cell specific, HMG-box)
23298
0.2
chr20_57723034_57723340 0.18 ZNF831
zinc finger protein 831
42888
0.16
chr2_98334024_98334251 0.17 ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
4114
0.2
chr22_40729451_40729738 0.16 ADSL
adenylosuccinate lyase
12913
0.18
chr9_95786987_95787346 0.16 FGD3
FYVE, RhoGEF and PH domain containing 3
9824
0.19
chr19_10874164_10874345 0.16 ENSG00000265879
.
16676
0.11
chr12_55382686_55382958 0.16 TESPA1
thymocyte expressed, positive selection associated 1
4292
0.26
chr11_60878524_60878675 0.16 CD5
CD5 molecule
8618
0.18
chr11_45856166_45856328 0.16 CRY2
cryptochrome 2 (photolyase-like)
12422
0.15
chr2_36474188_36474481 0.16 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
108735
0.08
chr2_111610099_111610292 0.15 ACOXL
acyl-CoA oxidase-like
47299
0.19
chr7_149561836_149562048 0.15 RP4-751H13.7

2361
0.25
chr22_20819732_20820026 0.15 ENSG00000255156
.
9719
0.1
chr15_44961507_44961922 0.15 PATL2
protein associated with topoisomerase II homolog 2 (yeast)
1031
0.46
chr11_121320555_121321108 0.15 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
2081
0.35
chr10_14593831_14594082 0.15 FAM107B
family with sequence similarity 107, member B
2272
0.38
chr15_52022956_52023209 0.15 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
7236
0.14
chr17_8801323_8801785 0.15 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
13270
0.21
chr6_128255047_128255301 0.15 THEMIS
thymocyte selection associated
15398
0.26
chr1_169662886_169663277 0.14 SELL
selectin L
17758
0.18
chr8_131260396_131260639 0.14 ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
1229
0.61
chr17_38758822_38758973 0.14 SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
29645
0.12
chr7_8172413_8172617 0.14 AC006042.6

18860
0.2
chr17_49505999_49506240 0.14 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
143490
0.04
chr10_22946008_22946242 0.14 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
56912
0.15
chr13_100039907_100040178 0.14 ENSG00000207719
.
31657
0.16
chr17_14097365_14097669 0.14 AC005224.2

16288
0.19
chr5_39181205_39181356 0.14 FYB
FYN binding protein
21849
0.24
chr19_16484143_16484894 0.14 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
11754
0.14
chr1_167598142_167598391 0.14 RCSD1
RCSD domain containing 1
1064
0.46
chr20_58639264_58639415 0.14 C20orf197
chromosome 20 open reading frame 197
8359
0.26
chr17_56422655_56423315 0.14 SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
6037
0.12
chr13_100024049_100024200 0.14 ENSG00000207719
.
15739
0.2
chr15_38979216_38979456 0.13 C15orf53
chromosome 15 open reading frame 53
9463
0.29
chr1_185250977_185251218 0.13 ENSG00000252612
.
15430
0.16
chr12_27124096_27124264 0.13 RP11-421F16.3

339
0.84
chr4_68447482_68447633 0.13 STAP1
signal transducing adaptor family member 1
23111
0.19
chr8_37134401_37134693 0.13 RP11-150O12.6

239992
0.02
chr7_50320921_50321337 0.13 IKZF1
IKAROS family zinc finger 1 (Ikaros)
23195
0.25
chr5_140981117_140981268 0.13 DIAPH1
diaphanous-related formin 1
14140
0.11
chr4_103510077_103510373 0.13 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
11204
0.22
chr1_206734639_206734815 0.13 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
4234
0.2
chr5_66118537_66118688 0.13 MAST4
microtubule associated serine/threonine kinase family member 4
5990
0.33
chr8_134531655_134531880 0.13 ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
20141
0.27
chr11_117800803_117801005 0.13 TMPRSS13
transmembrane protease, serine 13
730
0.65
chr8_61708195_61708346 0.13 RP11-33I11.2

13895
0.26
chr21_19155941_19156118 0.13 AL109761.5

9776
0.23
chrX_119553913_119554186 0.13 LAMP2
lysosomal-associated membrane protein 2
48798
0.13
chr4_3204868_3205180 0.13 MSANTD1
Myb/SANT-like DNA-binding domain containing 1
41072
0.15
chr19_3755879_3756030 0.13 AC005954.3

703
0.46
chr19_54872936_54873267 0.13 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
545
0.63
chr20_57722445_57722676 0.12 ZNF831
zinc finger protein 831
43515
0.15
chr2_68639578_68639939 0.12 AC015969.3

47042
0.11
chr2_113940950_113941232 0.12 AC016683.5

8154
0.14
chr16_68105212_68105363 0.12 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
13960
0.09
chr22_39714376_39714672 0.12 RPL3
ribosomal protein L3
95
0.87
chr5_39208813_39209149 0.12 FYB
FYN binding protein
5852
0.3
chr17_35032252_35032424 0.12 MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
73947
0.08
chr14_69280428_69280742 0.12 ZFP36L1
ZFP36 ring finger protein-like 1
17395
0.19
chr12_55143896_55144095 0.12 MUCL1
mucin-like 1
89158
0.07
chr14_90148267_90148437 0.12 ENSG00000200312
.
30503
0.14
chr4_164479105_164479708 0.12 ENSG00000264535
.
34962
0.17
chr13_52527282_52527433 0.12 ATP7B
ATPase, Cu++ transporting, beta polypeptide
8694
0.22
chrX_71321953_71322237 0.12 RGAG4
retrotransposon gag domain containing 4
29583
0.14
chr14_98640560_98640817 0.12 ENSG00000222066
.
157399
0.04
chr17_15493946_15494478 0.12 CDRT1
CMT1A duplicated region transcript 1
2510
0.2
chr2_237460577_237460750 0.12 ACKR3
atypical chemokine receptor 3
15767
0.24
chr14_107180053_107180204 0.12 IGHV2-70
immunoglobulin heavy variable 2-70
790
0.27
chr10_14622794_14622947 0.12 FAM107B
family with sequence similarity 107, member B
8532
0.25
chr19_4303888_4304210 0.12 FSD1
fibronectin type III and SPRY domain containing 1
548
0.54
chr1_24863399_24863781 0.12 ENSG00000266551
.
7386
0.17
chr14_22392361_22392865 0.12 ENSG00000222776
.
143828
0.04
chr17_76340922_76341205 0.12 SOCS3
suppressor of cytokine signaling 3
15092
0.14
chr2_197048278_197048429 0.12 STK17B
serine/threonine kinase 17b
7126
0.2
chr3_195277399_195277835 0.12 AC091633.3

4198
0.18
chr2_109225906_109226290 0.12 LIMS1
LIM and senescent cell antigen-like domains 1
2481
0.35
chr8_27235111_27235488 0.12 PTK2B
protein tyrosine kinase 2 beta
2869
0.31
chr7_50419027_50419178 0.12 IKZF1
IKAROS family zinc finger 1 (Ikaros)
51857
0.15
chr19_16473682_16473998 0.12 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
1076
0.45
chr1_109188164_109188315 0.11 HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
15438
0.19
chr16_23879975_23880302 0.11 PRKCB
protein kinase C, beta
31594
0.2
chr20_49546677_49546828 0.11 RP5-914P20.5

769
0.42
chr2_109646552_109646703 0.11 EDAR
ectodysplasin A receptor
40799
0.19
chr2_144070446_144070597 0.11 RP11-190J23.1

140780
0.05
chr17_18946909_18947248 0.11 GRAP
GRB2-related adaptor protein
1280
0.31
chr19_47125473_47125755 0.11 PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
2680
0.13
chr19_42276662_42276849 0.11 AC011513.4

14046
0.12
chr4_82483575_82483736 0.11 RASGEF1B
RasGEF domain family, member 1B
90586
0.1
chr1_160602079_160602495 0.11 SLAMF1
signaling lymphocytic activation molecule family member 1
14524
0.15
chr1_226901230_226901381 0.11 ITPKB
inositol-trisphosphate 3-kinase B
23854
0.18
chr17_47837882_47838168 0.11 FAM117A
family with sequence similarity 117, member A
3468
0.2
chr15_66113575_66113726 0.11 ENSG00000252715
.
22172
0.15
chr3_177269440_177269746 0.11 ENSG00000252028
.
48253
0.18
chr13_52404399_52404550 0.11 RP11-327P2.5

26041
0.16
chr1_229386021_229386325 0.11 TMEM78
transmembrane protein 78
790
0.59
chrX_13100415_13100651 0.11 FAM9C
family with sequence similarity 9, member C
37732
0.2
chr5_40592087_40592238 0.11 ENSG00000199552
.
62903
0.13
chr20_52302438_52302667 0.11 ENSG00000238468
.
17255
0.24
chr22_39385536_39385755 0.11 APOBEC3B
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
7231
0.12
chr3_32413325_32413665 0.11 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
19668
0.23
chr3_18431741_18431970 0.11 RP11-158G18.1

19272
0.22
chr1_27936707_27936953 0.11 AHDC1
AT hook, DNA binding motif, containing 1
6687
0.15
chr6_40407629_40407780 0.11 ENSG00000252767
.
32112
0.18
chr8_2212040_2212191 0.11 MYOM2
myomesin 2
218931
0.02
chr20_32592265_32592477 0.11 RALY
RALY heterogeneous nuclear ribonucleoprotein
10612
0.21
chr2_162811958_162812253 0.11 ENSG00000253046
.
36813
0.2
chr8_125575470_125576116 0.11 MTSS1
metastasis suppressor 1
2175
0.26
chr20_3071323_3071474 0.11 ENSG00000263905
.
3463
0.14
chr10_13160669_13160820 0.11 OPTN
optineurin
2476
0.29
chr6_159139178_159139369 0.11 ENSG00000265558
.
46512
0.12
chr2_192012454_192012731 0.11 STAT4
signal transducer and activator of transcription 4
3105
0.29
chr6_131520209_131520483 0.11 AKAP7
A kinase (PRKA) anchor protein 7
785
0.78
chr2_65046448_65046766 0.11 ENSG00000239891
.
2095
0.31
chr2_233565834_233565985 0.10 GIGYF2
GRB10 interacting GYF protein 2
3847
0.18
chr16_24161760_24161948 0.10 PRKCB
protein kinase C, beta
1152
0.63
chr1_211503644_211504001 0.10 TRAF5
TNF receptor-associated factor 5
3643
0.3
chr1_25319504_25319655 0.10 RUNX3
runt-related transcription factor 3
28078
0.16
chr7_45069539_45069790 0.10 CCM2
cerebral cavernous malformation 2
2393
0.23
chr2_7050734_7050964 0.10 RNF144A
ring finger protein 144A
6674
0.18
chr21_36340846_36341061 0.10 RUNX1
runt-related transcription factor 1
78866
0.12
chr1_206728493_206728745 0.10 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
1874
0.31
chr1_197737919_197738070 0.10 DENND1B
DENN/MADD domain containing 1B
6328
0.23
chr4_153507165_153507316 0.10 ENSG00000268471
.
49660
0.13
chr3_134013773_134013924 0.10 RYK
receptor-like tyrosine kinase
44159
0.16
chr8_82006436_82006760 0.10 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
17705
0.27
chr21_19164466_19164649 0.10 AL109761.5

1248
0.53
chr20_39784612_39784792 0.10 RP1-1J6.2

18059
0.18
chr14_53016892_53017043 0.10 TXNDC16
thioredoxin domain containing 16
2256
0.3
chr8_28917519_28917756 0.10 CTD-2647L4.4

4185
0.17
chr12_32044487_32044661 0.10 ENSG00000252584
.
24067
0.19
chr7_130737156_130737472 0.10 LINC-PINT
long intergenic non-protein coding RNA, p53 induced transcript
5
0.98
chr1_26861291_26861452 0.10 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
3552
0.18
chr16_49517590_49517775 0.10 C16orf78
chromosome 16 open reading frame 78
109948
0.07
chr16_12845026_12845177 0.10 CTD-2583P5.1

5371
0.19
chr2_54226465_54226799 0.10 ACYP2
acylphosphatase 2, muscle type
28387
0.17
chr22_37518928_37519269 0.10 TMPRSS6
transmembrane protease, serine 6
13495
0.11
chr8_38219385_38219619 0.10 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
18837
0.11
chr3_71829654_71829923 0.10 PROK2
prokineticin 2
4424
0.22
chr5_169693142_169693293 0.10 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
1083
0.57
chr6_156719174_156719407 0.10 ENSG00000212295
.
19406
0.3
chr17_47791372_47791523 0.10 SLC35B1
solute carrier family 35, member B1
5071
0.15
chr5_39208073_39208542 0.10 FYB
FYN binding protein
5178
0.31
chr15_70795218_70795369 0.10 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
199327
0.03
chr12_9760324_9760475 0.10 KLRB1
killer cell lectin-like receptor subfamily B, member 1
83
0.96
chr1_83973426_83973603 0.10 ENSG00000223231
.
286046
0.01
chr20_25034683_25034984 0.10 ACSS1
acyl-CoA synthetase short-chain family member 1
3985
0.24
chr2_204974005_204974290 0.10 ICOS
inducible T-cell co-stimulator
172644
0.03
chr14_68974151_68974302 0.10 RAD51B
RAD51 paralog B
95999
0.08
chr18_60972547_60972701 0.10 RP11-28F1.2

8691
0.18
chr14_66392899_66393124 0.10 CTD-2014B16.3
Uncharacterized protein
78230
0.11
chr5_40209101_40209266 0.10 ENSG00000199361
.
60477
0.15
chr9_129232305_129232865 0.10 ENSG00000252985
.
43413
0.14
chr11_118210971_118211165 0.10 CD3D
CD3d molecule, delta (CD3-TCR complex)
584
0.62
chr3_16984787_16984970 0.10 ENSG00000264818
.
10190
0.23
chr12_104870761_104871014 0.10 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
20108
0.25
chr8_68304910_68305240 0.10 ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
49163
0.18
chr12_50912843_50912995 0.10 DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
14029
0.22
chr15_91139735_91139886 0.10 CTD-3065B20.2

131
0.95
chrX_15768424_15768590 0.10 CA5B
carbonic anhydrase VB, mitochondrial
414
0.84
chr5_141484933_141485084 0.10 NDFIP1
Nedd4 family interacting protein 1
3062
0.32
chr1_117544919_117545104 0.10 CD101
CD101 molecule
577
0.73
chr6_158779170_158779472 0.10 RP11-732M18.2

40272
0.15
chr17_46529942_46530093 0.10 SKAP1
src kinase associated phosphoprotein 1
22436
0.11
chr7_101385381_101385615 0.10 CUX1
cut-like homeobox 1
73461
0.1
chr2_12642786_12642950 0.10 ENSG00000207183
.
91241
0.1
chr2_136983452_136983659 0.10 CXCR4
chemokine (C-X-C motif) receptor 4
107820
0.07
chr10_11193217_11193852 0.10 CELF2
CUGBP, Elav-like family member 2
13459
0.2
chr3_9821453_9821979 0.09 CAMK1
calcium/calmodulin-dependent protein kinase I
10040
0.09
chr13_99705776_99705927 0.09 ENSG00000207298
.
28363
0.16
chr6_13679192_13679414 0.09 ENSG00000252966
.
1009
0.51
chr2_198112450_198112630 0.09 ANKRD44
ankyrin repeat domain 44
49778
0.11
chr6_106099814_106099965 0.09 PREP
prolyl endopeptidase
248930
0.02
chr1_8485207_8485538 0.09 RERE
arginine-glutamic acid dipeptide (RE) repeats
100
0.78
chr10_8129790_8129941 0.09 GATA3
GATA binding protein 3
33096
0.25
chr14_55519381_55519591 0.09 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
1137
0.5
chr10_1748390_1748541 0.09 ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
31205
0.25
chr8_101442194_101442345 0.09 KB-1615E4.2

45634
0.12
chr10_64978992_64979347 0.09 JMJD1C
jumonji domain containing 1C
11684
0.25
chr15_45008051_45008236 0.09 B2M
beta-2-microglobulin
4428
0.17
chr2_182177306_182177486 0.09 ENSG00000266705
.
7017
0.32
chr12_15116052_15116331 0.09 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
1529
0.36
chr2_136881850_136882311 0.09 CXCR4
chemokine (C-X-C motif) receptor 4
6345
0.3
chr2_12636393_12636544 0.09 ENSG00000207183
.
84841
0.11
chr14_54905038_54905189 0.09 CNIH1
cornichon family AMPA receptor auxiliary protein 1
2945
0.28
chr14_23035018_23035185 0.09 AE000662.93

9145
0.11
chr12_67878065_67878216 0.09 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
163978
0.04
chr9_92141364_92141857 0.09 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
28565
0.19
chr10_126347896_126348047 0.09 FAM53B-AS1
FAM53B antisense RNA 1
44223
0.15
chr7_21393437_21393588 0.09 ENSG00000195024
.
27469
0.2
chr1_193448919_193449104 0.09 ENSG00000252241
.
252063
0.02
chr10_63792565_63792716 0.09 ARID5B
AT rich interactive domain 5B (MRF1-like)
16330
0.26
chrX_64947728_64947879 0.09 MSN
moesin
60266
0.16
chr11_118315811_118315962 0.09 KMT2A
lysine (K)-specific methyltransferase 2A
8409
0.11
chr12_11920815_11920993 0.09 ETV6
ets variant 6
15469
0.28
chr5_52021951_52022102 0.09 ITGA1
integrin, alpha 1
61704
0.12
chr15_38965720_38965889 0.09 C15orf53
chromosome 15 open reading frame 53
22995
0.24
chr5_133865434_133865585 0.09 JADE2
jade family PHD finger 2
3182
0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript