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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for HSF2

Z-value: 0.61

Motif logo

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
HSF2
ENSG00000025156.8 heat shock transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_122725724_122725875HSF251030.2893790.844.5e-03Click!
chr6_122733810_122733961HSF294160.2546510.818.6e-03Click!
chr6_122721794_122722012HSF212070.5895890.781.4e-02Click!
chr6_122722453_122722604HSF218320.4526370.771.6e-02Click!
chr6_122724067_122724218HSF234460.3264100.742.2e-02Click!

Activity of the HSF2 motif across conditions

Conditions sorted by the z-value of the HSF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_29289116_29289267 0.32 ENSG00000206704
 .
 23031
 0.18
chr14_99670994_99671151 0.24 AL162151.4
46319
 0.15
chr2_95741879_95742163 0.21 AC103563.9
23100
 0.15
chr5_133426970_133427238 0.19 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 23298
 0.2
chr20_57723034_57723340 0.18 ZNF831
 zinc finger protein 831
 42888
 0.16
chr2_98334024_98334251 0.17 ZAP70
 zeta-chain (TCR) associated protein kinase 70kDa
 4114
 0.2
chr22_40729451_40729738 0.16 ADSL
 adenylosuccinate lyase
 12913
 0.18
chr9_95786987_95787346 0.16 FGD3
 FYVE, RhoGEF and PH domain containing 3
 9824
 0.19
chr19_10874164_10874345 0.16 ENSG00000265879
 .
 16676
 0.11
chr12_55382686_55382958 0.16 TESPA1
 thymocyte expressed, positive selection associated 1
 4292
 0.26
chr11_60878524_60878675 0.16 CD5
 CD5 molecule
 8618
 0.18
chr11_45856166_45856328 0.16 CRY2
 cryptochrome 2 (photolyase-like)
 12422
 0.15
chr2_36474188_36474481 0.16 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 108735
 0.08
chr2_111610099_111610292 0.15 ACOXL
 acyl-CoA oxidase-like
 47299
 0.19
chr7_149561836_149562048 0.15 RP4-751H13.7
2361
 0.25
chr22_20819732_20820026 0.15 ENSG00000255156
 .
 9719
 0.1
chr15_44961507_44961922 0.15 PATL2
 protein associated with topoisomerase II homolog 2 (yeast)
 1031
 0.46
chr11_121320555_121321108 0.15 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 2081
 0.35
chr10_14593831_14594082 0.15 FAM107B
 family with sequence similarity 107, member B
 2272
 0.38
chr15_52022956_52023209 0.15 LYSMD2
 LysM, putative peptidoglycan-binding, domain containing 2
 7236
 0.14
chr17_8801323_8801785 0.15 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 13270
 0.21
chr6_128255047_128255301 0.15 THEMIS
 thymocyte selection associated
 15398
 0.26
chr1_169662886_169663277 0.14 SELL
 selectin L
 17758
 0.18
chr8_131260396_131260639 0.14 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 1229
 0.61
chr17_38758822_38758973 0.14 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 29645
 0.12
chr7_8172413_8172617 0.14 AC006042.6
18860
 0.2
chr17_49505999_49506240 0.14 UTP18
 UTP18 small subunit (SSU) processome component homolog (yeast)
 143490
 0.04
chr10_22946008_22946242 0.14 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 56912
 0.15
chr13_100039907_100040178 0.14 ENSG00000207719
 .
 31657
 0.16
chr17_14097365_14097669 0.14 AC005224.2
16288
 0.19
chr5_39181205_39181356 0.14 FYB
 FYN binding protein
 21849
 0.24
chr19_16484143_16484894 0.14 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 11754
 0.14
chr1_167598142_167598391 0.14 RCSD1
 RCSD domain containing 1
 1064
 0.46
chr20_58639264_58639415 0.14 C20orf197
 chromosome 20 open reading frame 197
 8359
 0.26
chr17_56422655_56423315 0.14 SUPT4H1
 suppressor of Ty 4 homolog 1 (S. cerevisiae)
 6037
 0.12
chr13_100024049_100024200 0.14 ENSG00000207719
 .
 15739
 0.2
chr15_38979216_38979456 0.13 C15orf53
 chromosome 15 open reading frame 53
 9463
 0.29
chr1_185250977_185251218 0.13 ENSG00000252612
 .
 15430
 0.16
chr12_27124096_27124264 0.13 RP11-421F16.3
339
 0.84
chr4_68447482_68447633 0.13 STAP1
 signal transducing adaptor family member 1
 23111
 0.19
chr8_37134401_37134693 0.13 RP11-150O12.6
239992
 0.02
chr7_50320921_50321337 0.13 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 23195
 0.25
chr5_140981117_140981268 0.13 DIAPH1
 diaphanous-related formin 1
 14140
 0.11
chr4_103510077_103510373 0.13 NFKB1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
 11204
 0.22
chr1_206734639_206734815 0.13 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 4234
 0.2
chr5_66118537_66118688 0.13 MAST4
 microtubule associated serine/threonine kinase family member 4
 5990
 0.33
chr8_134531655_134531880 0.13 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 20141
 0.27
chr11_117800803_117801005 0.13 TMPRSS13
 transmembrane protease, serine 13
 730
 0.65
chr8_61708195_61708346 0.13 RP11-33I11.2
13895
 0.26
chr21_19155941_19156118 0.13 AL109761.5
9776
 0.23
chrX_119553913_119554186 0.13 LAMP2
 lysosomal-associated membrane protein 2
 48798
 0.13
chr4_3204868_3205180 0.13 MSANTD1
 Myb/SANT-like DNA-binding domain containing 1
 41072
 0.15
chr19_3755879_3756030 0.13 AC005954.3
703
 0.46
chr19_54872936_54873267 0.13 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 545
 0.63
chr20_57722445_57722676 0.12 ZNF831
 zinc finger protein 831
 43515
 0.15
chr2_68639578_68639939 0.12 AC015969.3
47042
 0.11
chr2_113940950_113941232 0.12 AC016683.5
8154
 0.14
chr16_68105212_68105363 0.12 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
 13960
 0.09
chr22_39714376_39714672 0.12 RPL3
 ribosomal protein L3
 95
 0.87
chr5_39208813_39209149 0.12 FYB
 FYN binding protein
 5852
 0.3
chr17_35032252_35032424 0.12 MRM1
 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
 73947
 0.08
chr14_69280428_69280742 0.12 ZFP36L1
 ZFP36 ring finger protein-like 1
 17395
 0.19
chr12_55143896_55144095 0.12 MUCL1
 mucin-like 1
 89158
 0.07
chr14_90148267_90148437 0.12 ENSG00000200312
 .
 30503
 0.14
chr4_164479105_164479708 0.12 ENSG00000264535
 .
 34962
 0.17
chr13_52527282_52527433 0.12 ATP7B
 ATPase, Cu++ transporting, beta polypeptide
 8694
 0.22
chrX_71321953_71322237 0.12 RGAG4
 retrotransposon gag domain containing 4
 29583
 0.14
chr14_98640560_98640817 0.12 ENSG00000222066
 .
 157399
 0.04
chr17_15493946_15494478 0.12 CDRT1
 CMT1A duplicated region transcript 1
 2510
 0.2
chr2_237460577_237460750 0.12 ACKR3
 atypical chemokine receptor 3
 15767
 0.24
chr14_107180053_107180204 0.12 IGHV2-70
 immunoglobulin heavy variable 2-70
 790
 0.27
chr10_14622794_14622947 0.12 FAM107B
 family with sequence similarity 107, member B
 8532
 0.25
chr19_4303888_4304210 0.12 FSD1
 fibronectin type III and SPRY domain containing 1
 548
 0.54
chr1_24863399_24863781 0.12 ENSG00000266551
 .
 7386
 0.17
chr14_22392361_22392865 0.12 ENSG00000222776
 .
 143828
 0.04
chr17_76340922_76341205 0.12 SOCS3
 suppressor of cytokine signaling 3
 15092
 0.14
chr2_197048278_197048429 0.12 STK17B
 serine/threonine kinase 17b
 7126
 0.2
chr3_195277399_195277835 0.12 AC091633.3
4198
 0.18
chr2_109225906_109226290 0.12 LIMS1
 LIM and senescent cell antigen-like domains 1
 2481
 0.35
chr8_27235111_27235488 0.12 PTK2B
 protein tyrosine kinase 2 beta
 2869
 0.31
chr7_50419027_50419178 0.12 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 51857
 0.15
chr19_16473682_16473998 0.12 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 1076
 0.45
chr1_109188164_109188315 0.11 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 15438
 0.19
chr16_23879975_23880302 0.11 PRKCB
 protein kinase C, beta
 31594
 0.2
chr20_49546677_49546828 0.11 RP5-914P20.5
769
 0.42
chr2_109646552_109646703 0.11 EDAR
 ectodysplasin A receptor
 40799
 0.19
chr2_144070446_144070597 0.11 RP11-190J23.1
140780
 0.05
chr17_18946909_18947248 0.11 GRAP
 GRB2-related adaptor protein
 1280
 0.31
chr19_47125473_47125755 0.11 PTGIR
 prostaglandin I2 (prostacyclin) receptor (IP)
 2680
 0.13
chr19_42276662_42276849 0.11 AC011513.4
14046
 0.12
chr4_82483575_82483736 0.11 RASGEF1B
 RasGEF domain family, member 1B
 90586
 0.1
chr1_160602079_160602495 0.11 SLAMF1
 signaling lymphocytic activation molecule family member 1
 14524
 0.15
chr1_226901230_226901381 0.11 ITPKB
 inositol-trisphosphate 3-kinase B
 23854
 0.18
chr17_47837882_47838168 0.11 FAM117A
 family with sequence similarity 117, member A
 3468
 0.2
chr15_66113575_66113726 0.11 ENSG00000252715
 .
 22172
 0.15
chr3_177269440_177269746 0.11 ENSG00000252028
 .
 48253
 0.18
chr13_52404399_52404550 0.11 RP11-327P2.5
26041
 0.16
chr1_229386021_229386325 0.11 TMEM78
 transmembrane protein 78
 790
 0.59
chrX_13100415_13100651 0.11 FAM9C
 family with sequence similarity 9, member C
 37732
 0.2
chr5_40592087_40592238 0.11 ENSG00000199552
 .
 62903
 0.13
chr20_52302438_52302667 0.11 ENSG00000238468
 .
 17255
 0.24
chr22_39385536_39385755 0.11 APOBEC3B
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
 7231
 0.12
chr3_32413325_32413665 0.11 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 19668
 0.23
chr3_18431741_18431970 0.11 RP11-158G18.1
19272
 0.22
chr1_27936707_27936953 0.11 AHDC1
 AT hook, DNA binding motif, containing 1
 6687
 0.15
chr6_40407629_40407780 0.11 ENSG00000252767
 .
 32112
 0.18
chr8_2212040_2212191 0.11 MYOM2
 myomesin 2
 218931
 0.02
chr20_32592265_32592477 0.11 RALY
 RALY heterogeneous nuclear ribonucleoprotein
 10612
 0.21
chr2_162811958_162812253 0.11 ENSG00000253046
 .
 36813
 0.2
chr8_125575470_125576116 0.11 MTSS1
 metastasis suppressor 1
 2175
 0.26
chr20_3071323_3071474 0.11 ENSG00000263905
 .
 3463
 0.14
chr10_13160669_13160820 0.11 OPTN
 optineurin
 2476
 0.29
chr6_159139178_159139369 0.11 ENSG00000265558
 .
 46512
 0.12
chr2_192012454_192012731 0.11 STAT4
 signal transducer and activator of transcription 4
 3105
 0.29
chr6_131520209_131520483 0.11 AKAP7
 A kinase (PRKA) anchor protein 7
 785
 0.78
chr2_65046448_65046766 0.11 ENSG00000239891
 .
 2095
 0.31
chr2_233565834_233565985 0.10 GIGYF2
 GRB10 interacting GYF protein 2
 3847
 0.18
chr16_24161760_24161948 0.10 PRKCB
 protein kinase C, beta
 1152
 0.63
chr1_211503644_211504001 0.10 TRAF5
 TNF receptor-associated factor 5
 3643
 0.3
chr1_25319504_25319655 0.10 RUNX3
 runt-related transcription factor 3
 28078
 0.16
chr7_45069539_45069790 0.10 CCM2
 cerebral cavernous malformation 2
 2393
 0.23
chr2_7050734_7050964 0.10 RNF144A
 ring finger protein 144A
 6674
 0.18
chr21_36340846_36341061 0.10 RUNX1
 runt-related transcription factor 1
 78866
 0.12
chr1_206728493_206728745 0.10 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 1874
 0.31
chr1_197737919_197738070 0.10 DENND1B
 DENN/MADD domain containing 1B
 6328
 0.23
chr4_153507165_153507316 0.10 ENSG00000268471
 .
 49660
 0.13
chr3_134013773_134013924 0.10 RYK
 receptor-like tyrosine kinase
 44159
 0.16
chr8_82006436_82006760 0.10 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 17705
 0.27
chr21_19164466_19164649 0.10 AL109761.5
1248
 0.53
chr20_39784612_39784792 0.10 RP1-1J6.2
18059
 0.18
chr14_53016892_53017043 0.10 TXNDC16
 thioredoxin domain containing 16
 2256
 0.3
chr8_28917519_28917756 0.10 CTD-2647L4.4
4185
 0.17
chr12_32044487_32044661 0.10 ENSG00000252584
 .
 24067
 0.19
chr7_130737156_130737472 0.10 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 5
 0.98
chr1_26861291_26861452 0.10 RPS6KA1
 ribosomal protein S6 kinase, 90kDa, polypeptide 1
 3552
 0.18
chr16_49517590_49517775 0.10 C16orf78
 chromosome 16 open reading frame 78
 109948
 0.07
chr16_12845026_12845177 0.10 CTD-2583P5.1
5371
 0.19
chr2_54226465_54226799 0.10 ACYP2
 acylphosphatase 2, muscle type
 28387
 0.17
chr22_37518928_37519269 0.10 TMPRSS6
 transmembrane protease, serine 6
 13495
 0.11
chr8_38219385_38219619 0.10 WHSC1L1
 Wolf-Hirschhorn syndrome candidate 1-like 1
 18837
 0.11
chr3_71829654_71829923 0.10 PROK2
 prokineticin 2
 4424
 0.22
chr5_169693142_169693293 0.10 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 1083
 0.57
chr6_156719174_156719407 0.10 ENSG00000212295
 .
 19406
 0.3
chr17_47791372_47791523 0.10 SLC35B1
 solute carrier family 35, member B1
 5071
 0.15
chr5_39208073_39208542 0.10 FYB
 FYN binding protein
 5178
 0.31
chr15_70795218_70795369 0.10 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 199327
 0.03
chr12_9760324_9760475 0.10 KLRB1
 killer cell lectin-like receptor subfamily B, member 1
 83
 0.96
chr1_83973426_83973603 0.10 ENSG00000223231
 .
 286046
 0.01
chr20_25034683_25034984 0.10 ACSS1
 acyl-CoA synthetase short-chain family member 1
 3985
 0.24
chr2_204974005_204974290 0.10 ICOS
 inducible T-cell co-stimulator
 172644
 0.03
chr14_68974151_68974302 0.10 RAD51B
 RAD51 paralog B
 95999
 0.08
chr18_60972547_60972701 0.10 RP11-28F1.2
8691
 0.18
chr14_66392899_66393124 0.10 CTD-2014B16.3
 Uncharacterized protein
 78230
 0.11
chr5_40209101_40209266 0.10 ENSG00000199361
 .
 60477
 0.15
chr9_129232305_129232865 0.10 ENSG00000252985
 .
 43413
 0.14
chr11_118210971_118211165 0.10 CD3D
 CD3d molecule, delta (CD3-TCR complex)
 584
 0.62
chr3_16984787_16984970 0.10 ENSG00000264818
 .
 10190
 0.23
chr12_104870761_104871014 0.10 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 20108
 0.25
chr8_68304910_68305240 0.10 ARFGEF1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
 49163
 0.18
chr12_50912843_50912995 0.10 DIP2B
 DIP2 disco-interacting protein 2 homolog B (Drosophila)
 14029
 0.22
chr15_91139735_91139886 0.10 CTD-3065B20.2
131
 0.95
chrX_15768424_15768590 0.10 CA5B
 carbonic anhydrase VB, mitochondrial
 414
 0.84
chr5_141484933_141485084 0.10 NDFIP1
 Nedd4 family interacting protein 1
 3062
 0.32
chr1_117544919_117545104 0.10 CD101
 CD101 molecule
 577
 0.73
chr6_158779170_158779472 0.10 RP11-732M18.2
40272
 0.15
chr17_46529942_46530093 0.10 SKAP1
 src kinase associated phosphoprotein 1
 22436
 0.11
chr7_101385381_101385615 0.10 CUX1
 cut-like homeobox 1
 73461
 0.1
chr2_12642786_12642950 0.10 ENSG00000207183
 .
 91241
 0.1
chr2_136983452_136983659 0.10 CXCR4
 chemokine (C-X-C motif) receptor 4
 107820
 0.07
chr10_11193217_11193852 0.10 CELF2
 CUGBP, Elav-like family member 2
 13459
 0.2
chr3_9821453_9821979 0.09 CAMK1
 calcium/calmodulin-dependent protein kinase I
 10040
 0.09
chr13_99705776_99705927 0.09 ENSG00000207298
 .
 28363
 0.16
chr6_13679192_13679414 0.09 ENSG00000252966
 .
 1009
 0.51
chr2_198112450_198112630 0.09 ANKRD44
 ankyrin repeat domain 44
 49778
 0.11
chr6_106099814_106099965 0.09 PREP
 prolyl endopeptidase
 248930
 0.02
chr1_8485207_8485538 0.09 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 100
 0.78
chr10_8129790_8129941 0.09 GATA3
 GATA binding protein 3
 33096
 0.25
chr14_55519381_55519591 0.09 MAPK1IP1L
 mitogen-activated protein kinase 1 interacting protein 1-like
 1137
 0.5
chr10_1748390_1748541 0.09 ADARB2
 adenosine deaminase, RNA-specific, B2 (non-functional)
 31205
 0.25
chr8_101442194_101442345 0.09 KB-1615E4.2
45634
 0.12
chr10_64978992_64979347 0.09 JMJD1C
 jumonji domain containing 1C
 11684
 0.25
chr15_45008051_45008236 0.09 B2M
 beta-2-microglobulin
 4428
 0.17
chr2_182177306_182177486 0.09 ENSG00000266705
 .
 7017
 0.32
chr12_15116052_15116331 0.09 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 1529
 0.36
chr2_136881850_136882311 0.09 CXCR4
 chemokine (C-X-C motif) receptor 4
 6345
 0.3
chr2_12636393_12636544 0.09 ENSG00000207183
 .
 84841
 0.11
chr14_54905038_54905189 0.09 CNIH1
 cornichon family AMPA receptor auxiliary protein 1
 2945
 0.28
chr14_23035018_23035185 0.09 AE000662.93
9145
 0.11
chr12_67878065_67878216 0.09 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 163978
 0.04
chr9_92141364_92141857 0.09 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 28565
 0.19
chr10_126347896_126348047 0.09 FAM53B-AS1
 FAM53B antisense RNA 1
 44223
 0.15
chr7_21393437_21393588 0.09 ENSG00000195024
 .
 27469
 0.2
chr1_193448919_193449104 0.09 ENSG00000252241
 .
 252063
 0.02
chr10_63792565_63792716 0.09 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 16330
 0.26
chrX_64947728_64947879 0.09 MSN
 moesin
 60266
 0.16
chr11_118315811_118315962 0.09 KMT2A
 lysine (K)-specific methyltransferase 2A
 8409
 0.11
chr12_11920815_11920993 0.09 ETV6
 ets variant 6
 15469
 0.28
chr5_52021951_52022102 0.09 ITGA1
 integrin, alpha 1
 61704
 0.12
chr15_38965720_38965889 0.09 C15orf53
 chromosome 15 open reading frame 53
 22995
 0.24
chr5_133865434_133865585 0.09 JADE2
 jade family PHD finger 2
 3182
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.0 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript