Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for IKZF2

Z-value: 1.58

Motif logo

Transcription factors associated with IKZF2

Gene Symbol	Gene ID	Gene Info
IKZF2 Ensembl NCBI GeneCards UniProt	ENSG00000030419.12	IKAROS family zinc finger 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_213986421_213986572	IKZF2	26857	0.246949	-0.71	3.3e-02	Click!
chr2_214026642_214026793	IKZF2	9566	0.302902	0.67	4.7e-02	Click!
chr2_214010811_214010962	IKZF2	2467	0.425227	0.61	8.3e-02	Click!
chr2_213982929_213983080	IKZF2	30349	0.234874	-0.58	9.9e-02	Click!
chr2_213982732_213982883	IKZF2	30546	0.234186	-0.53	1.4e-01	Click!

Activity of the IKZF2 motif across conditions

Conditions sorted by the z-value of the IKZF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_116877788_116878085	0.44	FAM26D	family with sequence similarity 26, member D	3023	0.18
chr14_23006044_23006569	0.39	TRAJ15	T cell receptor alpha joining 15	7726	0.11
chr18_20558298_20558528	0.38	RBBP8	retinoblastoma binding protein 8	9608	0.15
chr11_3396621_3396905	0.36	ENSG00000263365	.	1912	0.25
chr13_30160711_30160862	0.36	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	143	0.98
chr1_65372485_65372704	0.36	JAK1	Janus kinase 1	59593	0.13
chr2_101437963_101438114	0.35	NPAS2	neuronal PAS domain protein 2	551	0.67
chr17_48812709_48812860	0.32	LUC7L3	LUC7-like 3 (S. cerevisiae)	1212	0.39
chr8_29109260_29109557	0.30	KIF13B	kinesin family member 13B	11182	0.17
chr16_14030624_14030775	0.30	CTD-2135D7.2		1207	0.56
chr4_170038040_170038191	0.28	RP11-327O17.2		84830	0.08
chr9_124005105_124005256	0.28	RAB14	RAB14, member RAS oncogene family	19888	0.13
chr6_42326971_42327197	0.28	ENSG00000221252	.	53050	0.13
chr4_103998432_103998637	0.27	SLC9B2	solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2	53	0.98
chr2_30458978_30459361	0.27	LBH	limb bud and heart development	4123	0.28
chr7_116270780_116270931	0.26	MET	met proto-oncogene	41589	0.14
chr2_152115718_152115869	0.26	RBM43	RNA binding motif protein 43	2499	0.33
chr22_20919404_20919765	0.26	MED15	mediator complex subunit 15	14007	0.14
chr3_184055469_184055620	0.25	FAM131A	family with sequence similarity 131, member A	304	0.8
chr18_13378456_13378780	0.25	LDLRAD4	low density lipoprotein receptor class A domain containing 4	3935	0.19
chr9_97631859_97632254	0.25	RP11-49O14.2		30655	0.15
chr8_38782658_38783281	0.25	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	24107	0.14
chr7_55141300_55141512	0.25	EGFR	epidermal growth factor receptor	36010	0.22
chr1_92220198_92220349	0.24	ENSG00000239794	.	75358	0.11
chr3_38875961_38876357	0.24	RP11-134J21.1		10766	0.19
chr15_38779165_38779950	0.24	RP11-102L12.2		15497	0.17
chr8_22320352_22320708	0.24	PPP3CC	protein phosphatase 3, catalytic subunit, gamma isozyme	12575	0.15
chr18_55863805_55863956	0.24	RP11-718I15.1		952	0.42
chr3_66062574_66062725	0.24	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	38424	0.17
chr6_112078721_112079214	0.24	FYN	FYN oncogene related to SRC, FGR, YES	1350	0.56
chr4_129744671_129744822	0.24	JADE1	jade family PHD finger 1	7842	0.3
chr17_41495072_41495223	0.24	ENSG00000251763	.	5352	0.12
chr10_74004394_74004633	0.23	ENSG00000200170	.	24003	0.12
chr6_114287058_114287209	0.23	HDAC2	histone deacetylase 2	2561	0.27
chr6_112127086_112127660	0.23	FYN	FYN oncogene related to SRC, FGR, YES	7747	0.29
chr22_38281441_38281592	0.23	ENSG00000207227	.	5838	0.1
chr2_102443416_102443820	0.23	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	12672	0.26
chr17_47896409_47896901	0.23	RP11-304F15.3		26617	0.12
chrX_30893495_30893646	0.23	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	8251	0.21
chr1_93399148_93399403	0.23	FAM69A	family with sequence similarity 69, member A	27782	0.11
chr11_35268427_35268939	0.22	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	18609	0.14
chr16_87469163_87469969	0.22	ZCCHC14	zinc finger, CCHC domain containing 14	2826	0.22
chr6_133944571_133944722	0.22	RP3-323P13.2		111780	0.07
chr1_156099255_156099406	0.22	LMNA	lamin A/C	2736	0.16
chr17_39533966_39534194	0.22	KRT34	keratin 34	4575	0.1
chr18_7812137_7812288	0.22	RP11-678G15.1		1904	0.35
chr9_114812031_114812182	0.22	RP11-4O1.2		12096	0.2
chr11_128340661_128340942	0.21	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	34488	0.2
chr10_33251015_33251258	0.21	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1075	0.65
chr3_40505730_40505995	0.21	RPL14	ribosomal protein L14	7017	0.15
chr11_96039540_96039791	0.21	ENSG00000266192	.	34937	0.17
chrY_21903585_21903736	0.21	KDM5D	lysine (K)-specific demethylase 5D	2937	0.4
chr3_130936015_130936300	0.21	ENSG00000265235	.	28915	0.19
chr9_34203797_34204061	0.21	ENSG00000252164	.	2310	0.22
chr7_46495799_46495950	0.21	AC011294.3	Uncharacterized protein	240846	0.02
chr6_127527843_127527994	0.21	RNF146	ring finger protein 146	59837	0.13
chr10_119300742_119300893	0.21	EMX2OS	EMX2 opposite strand/antisense RNA	1013	0.44
chr19_13373156_13373307	0.21	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	5017	0.22
chr16_22398221_22398372	0.21	CDR2	cerebellar degeneration-related protein 2, 62kDa	11885	0.14
chr2_30477316_30477615	0.21	LBH	limb bud and heart development	22419	0.22
chr8_13303389_13303540	0.21	DLC1	deleted in liver cancer 1	53286	0.15
chr22_18405059_18405210	0.21	MICAL3	microtubule associated monooxygenase, calponin and LIM domain containing 3	15494	0.19
chr2_238338921_238339072	0.21	AC112721.1	Uncharacterized protein	5077	0.22
chr6_143172108_143172466	0.21	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	14103	0.27
chr3_105504443_105504594	0.21	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	83369	0.11
chr2_55818169_55818320	0.21	ENSG00000212175	.	25405	0.14
chr3_23852622_23853296	0.21	UBE2E1	ubiquitin-conjugating enzyme E2E 1	10	0.98
chr11_82780511_82780748	0.21	RAB30	RAB30, member RAS oncogene family	2241	0.29
chr1_151963809_151963960	0.21	S100A10	S100 calcium binding protein A10	1170	0.39
chr8_117753205_117753356	0.21	EIF3H	eukaryotic translation initiation factor 3, subunit H	14743	0.21
chr6_159271708_159272064	0.21	C6orf99	chromosome 6 open reading frame 99	19085	0.16
chr11_60828326_60828529	0.20	CD5	CD5 molecule	41440	0.11
chr4_143327756_143327922	0.20	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	24573	0.29
chr1_202249577_202249728	0.20	ENSG00000239046	.	48860	0.1
chr2_191723875_191724026	0.20	GLS	glutaminase	21603	0.2
chr15_42227548_42227790	0.20	CTD-2382E5.4		14054	0.11
chr3_192606561_192606956	0.20	MB21D2	Mab-21 domain containing 2	29192	0.24
chr16_24785300_24785451	0.20	TNRC6A	trinucleotide repeat containing 6A	17433	0.22
chr3_141928282_141928433	0.20	GK5	glycerol kinase 5 (putative)	16071	0.22
chr4_141968010_141968161	0.20	RNF150	ring finger protein 150	6795	0.32
chr6_148662831_148662982	0.20	SASH1	SAM and SH3 domain containing 1	823	0.72
chr17_7213721_7213907	0.20	EIF5A	eukaryotic translation initiation factor 5A	2124	0.1
chr14_52821102_52821350	0.20	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	40113	0.19
chr21_36168084_36168235	0.20	AP000330.8		50025	0.16
chr17_34909042_34909369	0.20	GGNBP2	gametogenetin binding protein 2	7852	0.13
chr7_130587786_130587937	0.20	ENSG00000226380	.	25563	0.22
chr9_108737188_108737339	0.20	TMEM38B	transmembrane protein 38B	253295	0.02
chr4_7905515_7905666	0.20	AFAP1	actin filament associated protein 1	31550	0.17
chr12_13348032_13348183	0.20	EMP1	epithelial membrane protein 1	1543	0.49
chr9_111858912_111859063	0.20	TMEM245	transmembrane protein 245	9414	0.19
chr19_13132424_13132703	0.20	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	2242	0.17
chr17_2310516_2310667	0.20	MNT	MAX network transcriptional repressor	6179	0.12
chr6_121969345_121969496	0.20	ENSG00000222659	.	67753	0.13
chr13_100743473_100743624	0.20	PCCA	propionyl CoA carboxylase, alpha polypeptide	2211	0.41
chr11_119112060_119112211	0.19	CBL	Cbl proto-oncogene, E3 ubiquitin protein ligase	35383	0.08
chr20_51832864_51833015	0.19	RP11-15M15.2		7695	0.21
chr4_143318453_143318604	0.19	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	33884	0.25
chr9_74375544_74375695	0.19	TMEM2	transmembrane protein 2	7683	0.3
chr10_74004680_74004925	0.19	ENSG00000200170	.	24292	0.12
chr14_64335207_64335619	0.19	SYNE2	spectrin repeat containing, nuclear envelope 2	15681	0.21
chr15_70991883_70992034	0.19	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	2662	0.37
chr6_42307045_42307377	0.19	ENSG00000221252	.	72923	0.09
chr10_103446662_103446813	0.19	FBXW4	F-box and WD repeat domain containing 4	8279	0.19
chr1_86158252_86158403	0.19	ZNHIT6	zinc finger, HIT-type containing 6	15774	0.25
chr12_69922390_69922541	0.19	FRS2	fibroblast growth factor receptor substrate 2	2138	0.34
chr14_61932790_61932961	0.19	PRKCH	protein kinase C, eta	23599	0.2
chr15_42640019_42640170	0.19	CAPN3	calpain 3, (p94)	207	0.93
chr13_24253099_24253504	0.19	AL139080.1	Uncharacterized protein	68942	0.11
chr1_218649534_218649685	0.19	C1orf143	chromosome 1 open reading frame 143	33829	0.2
chr12_76115257_76115408	0.19	ENSG00000264062	.	2989	0.33
chr1_150662741_150662892	0.19	GOLPH3L	golgi phosphoprotein 3-like	6684	0.13
chr10_33538186_33538377	0.19	NRP1	neuropilin 1	14351	0.21
chr10_43895608_43895896	0.19	HNRNPF	heterogeneous nuclear ribonucleoprotein F	2958	0.21
chr2_37686183_37686412	0.19	ENSG00000253078	.	23546	0.21
chr16_71671220_71671371	0.19	MARVELD3	MARVEL domain containing 3	8322	0.1
chr5_143546729_143546880	0.19	YIPF5	Yip1 domain family, member 5	3390	0.25
chr3_66027202_66027443	0.19	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3097	0.3
chr14_99730019_99730213	0.19	AL109767.1		831	0.66
chr8_69838287_69838438	0.19	ENSG00000238808	.	184447	0.03
chr1_151962516_151962768	0.19	S100A10	S100 calcium binding protein A10	2412	0.22
chr12_57628145_57628477	0.19	SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	2067	0.16
chr3_177801896_177802095	0.19	ENSG00000199858	.	76428	0.12
chr11_121973042_121973193	0.19	RP11-166D19.1		231	0.91
chr16_68485211_68485362	0.19	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	2695	0.23
chr8_32180787_32180938	0.19	ENSG00000200246	.	66850	0.12
chr10_63512082_63512376	0.19	RP11-63A2.2		67083	0.12
chr6_112127691_112127942	0.19	FYN	FYN oncogene related to SRC, FGR, YES	8190	0.29
chr10_15208005_15208246	0.19	NMT2	N-myristoyltransferase 2	2320	0.33
chr2_172128341_172128492	0.19	TLK1	tousled-like kinase 1	40592	0.18
chr2_225086781_225086932	0.19	ENSG00000211987	.	17417	0.28
chr1_205142673_205142824	0.19	DSTYK	dual serine/threonine and tyrosine protein kinase	37946	0.12
chr5_73612868_73613019	0.19	ENSG00000244326	.	868	0.71
chr11_11867982_11868133	0.19	USP47	ubiquitin specific peptidase 47	4444	0.33
chr9_119463950_119464101	0.19	TRIM32	tripartite motif containing 32	14403	0.22
chr6_52416562_52416716	0.19	TRAM2	translocation associated membrane protein 2	25074	0.22
chr1_221614582_221614778	0.18	DUSP10	dual specificity phosphatase 10	296122	0.01
chr18_21633829_21634342	0.18	TTC39C	tetratricopeptide repeat domain 39C	37487	0.11
chr13_40767790_40767941	0.18	ENSG00000207458	.	33099	0.24
chr13_101045927_101046215	0.18	PCCA	propionyl CoA carboxylase, alpha polypeptide	25318	0.23
chr16_4264572_4264723	0.18	SRL	sarcalumenin	25097	0.17
chr6_24883063_24883351	0.18	FAM65B	family with sequence similarity 65, member B	5624	0.23
chr6_86164371_86164522	0.18	NT5E	5'-nucleotidase, ecto (CD73)	4619	0.31
chr2_145853230_145853381	0.18	ENSG00000253036	.	239333	0.02
chr17_13251602_13251753	0.18	ENSG00000266115	.	151968	0.04
chr4_99444287_99444438	0.18	RP11-724M22.1		26847	0.24
chr8_103741522_103741773	0.18	ENSG00000266799	.	4300	0.27
chr11_128372954_128373665	0.18	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	1980	0.4
chr11_128381097_128381643	0.18	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	6081	0.25
chr6_36946763_36946914	0.18	MTCH1	mitochondrial carrier 1	1389	0.4
chr8_25117778_25117929	0.18	DOCK5	dedicator of cytokinesis 5	38605	0.19
chr7_130630277_130630707	0.18	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	38376	0.18
chr18_57365633_57365784	0.18	CCBE1	collagen and calcium binding EGF domains 1	1096	0.44
chr18_55975063_55975214	0.18	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	15414	0.22
chr6_160399730_160400221	0.18	IGF2R	insulin-like growth factor 2 receptor	9844	0.21
chr12_3328021_3328172	0.18	TSPAN9	tetraspanin 9	17755	0.24
chr11_48192181_48192553	0.18	OR4B1	olfactory receptor, family 4, subfamily B, member 1	45977	0.13
chr1_202548605_202548756	0.18	RP11-569A11.1		24716	0.18
chr11_92002095_92002246	0.18	FAT3	FAT atypical cadherin 3	83092	0.11
chr12_90084691_90084842	0.18	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	17842	0.19
chr14_64332649_64332871	0.18	SYNE2	spectrin repeat containing, nuclear envelope 2	13028	0.21
chr8_91682668_91682819	0.18	RP11-68L18.1		21767	0.2
chr22_20900238_20900389	0.18	MED15	mediator complex subunit 15	4961	0.15
chr1_214646887_214647162	0.18	PTPN14	protein tyrosine phosphatase, non-receptor type 14	8878	0.3
chr5_54892777_54892928	0.18	PPAP2A	phosphatidic acid phosphatase type 2A	61974	0.11
chr1_24790818_24790969	0.18	NIPAL3	NIPA-like domain containing 3	8237	0.18
chr2_225746364_225746903	0.18	DOCK10	dedicator of cytokinesis 10	65149	0.14
chr11_68768633_68768911	0.18	RP11-554A11.4		744	0.51
chr14_100434768_100434919	0.18	EVL	Enah/Vasp-like	2943	0.26
chr17_57439100_57439642	0.18	ENSG00000263857	.	4073	0.2
chr11_94539031_94539182	0.18	AMOTL1	angiomotin like 1	37569	0.17
chr9_33414190_33414341	0.18	RP11-311H10.4		11410	0.14
chr5_54605298_54605894	0.18	SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	1767	0.29
chr7_27813849_27814000	0.18	TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	18833	0.21
chr3_81265699_81265850	0.18	ENSG00000222389	.	292853	0.01
chr1_23664610_23664879	0.18	HNRNPR	heterogeneous nuclear ribonucleoprotein R	6011	0.16
chr4_114679396_114679562	0.18	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	2745	0.42
chr5_131355905_131356056	0.18	ACSL6	acyl-CoA synthetase long-chain family member 6	8110	0.14
chr1_12466917_12467188	0.18	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	2872	0.34
chr22_42013582_42013733	0.18	DESI1	desumoylating isopeptidase 1	3443	0.14
chr3_69834642_69834793	0.18	ENSG00000241665	.	15789	0.23
chr15_67367308_67367832	0.18	SMAD3	SMAD family member 3	9387	0.28
chr14_96982092_96982363	0.18	PAPOLA	poly(A) polymerase alpha	11552	0.18
chr2_158605215_158605366	0.18	ACVR1	activin A receptor, type I	58218	0.13
chr17_35906348_35906499	0.18	SYNRG	synergin, gamma	3935	0.23
chr12_105608187_105608338	0.18	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	15376	0.21
chr17_6527918_6528069	0.18	KIAA0753	KIAA0753	3834	0.13
chr5_180286437_180286588	0.18	ZFP62	ZFP62 zinc finger protein	1151	0.46
chr8_42143739_42143890	0.18	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	14224	0.15
chr17_20902840_20902991	0.17	RP11-746M1.1		145	0.95
chr4_48695143_48695294	0.17	FRYL	FRY-like	12030	0.26
chr18_56529967_56530118	0.17	ZNF532	zinc finger protein 532	138	0.96
chr2_102326009_102326243	0.17	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	11134	0.3
chr3_56925362_56925595	0.17	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	25021	0.21
chr8_100715929_100716325	0.17	ENSG00000243254	.	89821	0.08
chr17_16133762_16133975	0.17	NCOR1	nuclear receptor corepressor 1	12369	0.15
chr18_72662833_72662984	0.17	ZADH2	zinc binding alcohol dehydrogenase domain containing 2	254560	0.02
chr22_24763474_24763625	0.17	ADORA2A	adenosine A2a receptor	56016	0.1
chr21_44144056_44144280	0.17	AP001627.1		17700	0.2
chr10_3929538_3929752	0.17	KLF6	Kruppel-like factor 6	102172	0.08
chr14_98648496_98648874	0.17	ENSG00000222066	.	149402	0.04

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.3	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.1	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.3	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.6	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.2	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0070099	Roundabout signaling pathway(GO:0035385) regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.2	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0072141	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0090312	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.2	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0033087	regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.1	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0072189	ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0061054	positive regulation of cell adhesion mediated by integrin(GO:0033630) dermatome development(GO:0061054)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0070602	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.0	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0072202	cell differentiation involved in metanephros development(GO:0072202)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.0	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.1	GO:0072283	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) metanephric renal vesicle morphogenesis(GO:0072283)
0.0	0.0	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0043650	dicarboxylic acid biosynthetic process(GO:0043650)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0098801	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0	0.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.0	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701) regulation of gastric acid secretion(GO:0060453)
0.0	0.0	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0042634	regulation of hair cycle(GO:0042634)
0.0	0.0	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.3	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0	0.0	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.6	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.9	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.2	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0090079	translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.9	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	PID BMP PATHWAY	BMP receptor signaling
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.0	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation

Results for IKZF2

Z-value: 1.58

Motif logo

Transcription factors associated with IKZF2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IKZF2 motif across conditions

Conditions sorted by the z-value of the IKZF2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: