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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for IRF9

Z-value: 0.97

Motif logo

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.4 IRF9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
IRF9chr14_24632118_246326851960.8086710.722.7e-02Click!
IRF9chr14_24631008_246312826350.391531-0.655.6e-02Click!
IRF9chr14_24629657_246298085300.4538050.646.2e-02Click!
IRF9chr14_24633422_2463361813150.1686600.627.4e-02Click!
IRF9chr14_24630607_246307581720.827781-0.511.7e-01Click!

Activity of the IRF9 motif across conditions

Conditions sorted by the z-value of the IRF9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_28308673_28308825 0.61 SBK1
 SH3 domain binding kinase 1
 4909
 0.23
chr6_5984279_5984492 0.56 NRN1
 neuritin 1
 22815
 0.22
chr5_110585847_110586110 0.49 AC010468.2
19809
 0.19
chr3_53380740_53380960 0.44 DCP1A
 decapping mRNA 1A
 702
 0.63
chr12_12679407_12679558 0.41 DUSP16
 dual specificity phosphatase 16
 5423
 0.27
chr4_123134100_123134251 0.39 KIAA1109
 KIAA1109
 6449
 0.31
chr21_34561335_34561486 0.38 C21orf54
 chromosome 21 open reading frame 54
 18869
 0.14
chr16_10946685_10946855 0.38 CIITA
 class II, major histocompatibility complex, transactivator
 24285
 0.14
chr7_37354921_37355641 0.36 ELMO1
 engulfment and cell motility 1
 27086
 0.19
chr2_202137440_202137733 0.36 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 225
 0.94
chr6_167531770_167531921 0.36 CCR6
 chemokine (C-C motif) receptor 6
 4412
 0.22
chr15_61461534_61461839 0.35 RP11-39M21.1
11762
 0.24
chr10_28865947_28866098 0.35 WAC
 WW domain containing adaptor with coiled-coil
 42970
 0.13
chr14_99676221_99676413 0.35 AL162151.4
51564
 0.13
chr12_111169275_111169426 0.33 PPP1CC
 protein phosphatase 1, catalytic subunit, gamma isozyme
 1438
 0.43
chr1_41160253_41160404 0.33 NFYC
 nuclear transcription factor Y, gamma
 2366
 0.22
chr11_122953732_122953925 0.33 HSPA8
 heat shock 70kDa protein 8
 19890
 0.14
chr19_47026380_47026531 0.33 PNMAL2
 paraneoplastic Ma antigen family-like 2
 26700
 0.11
chr4_15549194_15549345 0.31 RP11-799M12.2
16607
 0.21
chr8_42742820_42742971 0.31 ENSG00000242719
 .
 6516
 0.13
chr1_167644846_167644997 0.31 RP3-455J7.4
45010
 0.13
chr2_68316449_68316600 0.31 C1D
 C1D nuclear receptor corepressor
 26367
 0.18
chr9_6447465_6447616 0.31 RP11-307L3.4
2018
 0.32
chr5_110671729_110671880 0.31 CTC-499J9.1
33539
 0.19
chr9_73280058_73280209 0.30 RP11-141J10.1
42830
 0.16
chrX_124428136_124428287 0.30 ENSG00000263886
 .
 6586
 0.34
chr3_186598137_186598377 0.30 ADIPOQ-AS1
 ADIPOQ antisense RNA 1
 24345
 0.12
chr22_40641601_40641853 0.30 TNRC6B
 trinucleotide repeat containing 6B
 19280
 0.23
chr1_185303339_185303490 0.29 IVNS1ABP
 influenza virus NS1A binding protein
 16953
 0.21
chr1_198512680_198513141 0.29 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 2835
 0.39
chr2_134955729_134956031 0.28 ENSG00000222921
 .
 32886
 0.2
chr2_26016237_26016499 0.28 ASXL2
 additional sex combs like 2 (Drosophila)
 13190
 0.24
chr3_187520764_187520915 0.28 BCL6
 B-cell CLL/lymphoma 6
 57324
 0.14
chr13_39669679_39669830 0.28 NHLRC3
 NHL repeat containing 3
 57226
 0.13
chr17_58585749_58585900 0.28 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
 17660
 0.16
chr12_69641508_69641703 0.28 CPSF6
 cleavage and polyadenylation specific factor 6, 68kDa
 8183
 0.25
chr10_31286988_31287139 0.27 ZNF438
 zinc finger protein 438
 1383
 0.56
chr1_116013920_116014071 0.27 ENSG00000265534
 .
 14277
 0.26
chr1_54382309_54382460 0.27 DIO1
 deiodinase, iodothyronine, type I
 22500
 0.12
chr15_52975962_52976192 0.27 FAM214A
 family with sequence similarity 214, member A
 4508
 0.26
chr3_193332036_193332187 0.26 OPA1
 optic atrophy 1 (autosomal dominant)
 670
 0.67
chr22_20907241_20907489 0.26 MED15
 mediator complex subunit 15
 1788
 0.28
chrX_12986253_12986505 0.26 TMSB4X
 thymosin beta 4, X-linked
 6848
 0.23
chr2_99077021_99077380 0.26 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 15787
 0.23
chr14_75580842_75580993 0.26 NEK9
 NIMA-related kinase 9
 12826
 0.13
chr1_91387563_91387714 0.26 ZNF644
 zinc finger protein 644
 99376
 0.09
chr1_209397111_209397262 0.25 ENSG00000230937
 .
 208292
 0.02
chr3_66354688_66354873 0.25 ENSG00000206759
 .
 11136
 0.22
chr2_223160387_223160795 0.25 CCDC140
 coiled-coil domain containing 140
 2275
 0.28
chr10_27634072_27634223 0.25 ENSG00000207135
 .
 9611
 0.19
chr11_118087201_118087579 0.25 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 1784
 0.28
chr12_55159564_55159715 0.25 MUCL1
 mucin-like 1
 73514
 0.09
chr19_21501017_21501168 0.24 ZNF708
 zinc finger protein 708
 11046
 0.23
chr3_153005640_153005791 0.23 ENSG00000265813
 .
 87909
 0.09
chr1_8487706_8487969 0.23 RP5-1115A15.1
2139
 0.29
chrX_37209381_37209588 0.23 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
 852
 0.45
chr7_37374563_37374714 0.23 ELMO1
 engulfment and cell motility 1
 7729
 0.22
chr3_171131433_171131584 0.23 ENSG00000222506
 .
 25807
 0.21
chr9_92031645_92032185 0.23 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1833
 0.43
chrX_19761612_19761864 0.23 SH3KBP1
 SH3-domain kinase binding protein 1
 2783
 0.4
chr15_38843563_38843770 0.22 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 8617
 0.18
chr2_136809392_136809630 0.22 AC093391.2
39476
 0.17
chr12_14958204_14958570 0.22 C12orf60
 chromosome 12 open reading frame 60
 1881
 0.19
chr1_14066743_14066960 0.22 PRDM2
 PR domain containing 2, with ZNF domain
 9047
 0.24
chr21_34558500_34558796 0.22 C21orf54
 chromosome 21 open reading frame 54
 16107
 0.15
chr3_38246802_38246978 0.22 OXSR1
 oxidative stress responsive 1
 39894
 0.12
chr2_55448215_55448382 0.22 CLHC1
 clathrin heavy chain linker domain containing 1
 3198
 0.18
chr1_111206032_111206245 0.22 ENSG00000221538
 .
 10485
 0.17
chr19_34761920_34762071 0.21 KIAA0355
 KIAA0355
 16493
 0.21
chr11_59278455_59278686 0.21 OR4D9
 olfactory receptor, family 4, subfamily D, member 9
 3816
 0.14
chr15_22549120_22549388 0.21 ENSG00000221641
 .
 35974
 0.13
chr18_76845896_76846047 0.21 ATP9B
 ATPase, class II, type 9B
 16481
 0.23
chr10_43639918_43640069 0.21 CSGALNACT2
 chondroitin sulfate N-acetylgalactosaminyltransferase 2
 6059
 0.25
chr6_146188270_146188476 0.21 SHPRH
 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
 26117
 0.2
chr3_171827366_171827628 0.21 FNDC3B
 fibronectin type III domain containing 3B
 17267
 0.27
chr14_102667167_102667383 0.21 WDR20
 WD repeat domain 20
 5992
 0.21
chr5_56142442_56142699 0.21 ENSG00000238717
 .
 10405
 0.16
chr1_154758471_154758622 0.21 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
 73773
 0.07
chr1_206258212_206258472 0.21 ENSG00000252692
 .
 2751
 0.24
chr16_50802191_50802342 0.21 CYLD
 cylindromatosis (turban tumor syndrome)
 18806
 0.11
chr3_9698001_9698152 0.21 MTMR14
 myotubularin related protein 14
 6880
 0.18
chr22_50974630_50974781 0.21 ODF3B
 outer dense fiber of sperm tails 3B
 3696
 0.08
chr17_64669218_64669401 0.21 AC006947.1
3181
 0.27
chr4_123072179_123072451 0.20 KIAA1109
 KIAA1109
 1173
 0.61
chr11_10820253_10820514 0.20 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
 1646
 0.26
chr1_47695775_47695926 0.20 TAL1
 T-cell acute lymphocytic leukemia 1
 407
 0.81
chr1_193537243_193537394 0.20 ENSG00000252241
 .
 163756
 0.04
chr13_74599356_74599708 0.20 KLF12
 Kruppel-like factor 12
 30346
 0.26
chrX_40949750_40950076 0.20 USP9X
 ubiquitin specific peptidase 9, X-linked
 5025
 0.32
chr13_96871005_96871156 0.20 ENSG00000242614
 .
 49281
 0.18
chr2_175489102_175489253 0.20 WIPF1
 WAS/WASL interacting protein family, member 1
 10130
 0.21
chr13_48755718_48755869 0.20 ITM2B
 integral membrane protein 2B
 51501
 0.14
chr2_239266363_239266514 0.20 TRAF3IP1
 TNF receptor-associated factor 3 interacting protein 1
 37253
 0.11
chr7_8181242_8181393 0.20 ENSG00000265212
 .
 13335
 0.21
chr2_144079139_144079290 0.20 RP11-190J23.1
149473
 0.04
chr10_32655032_32655284 0.20 EPC1
 enhancer of polycomb homolog 1 (Drosophila)
 12568
 0.13
chr2_44417617_44417768 0.20 PPM1B
 protein phosphatase, Mg2+/Mn2+ dependent, 1B
 10633
 0.17
chr2_86080156_86080307 0.20 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
 14546
 0.17
chr1_158968333_158968541 0.20 IFI16
 interferon, gamma-inducible protein 16
 1321
 0.48
chr3_107792267_107792418 0.20 CD47
 CD47 molecule
 13963
 0.29
chr1_160653626_160654131 0.20 RP11-404F10.2
10566
 0.15
chr2_197064558_197064822 0.20 ENSG00000239161
 .
 15356
 0.18
chr3_15389616_15389998 0.19 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 6932
 0.15
chr1_110889550_110889701 0.19 RBM15
 RNA binding motif protein 15
 7680
 0.13
chr16_58653793_58653944 0.19 ENSG00000239121
 .
 1289
 0.4
chr2_199237056_199237207 0.19 ENSG00000252511
 .
 194322
 0.03
chr13_40720807_40721155 0.19 ENSG00000207458
 .
 79983
 0.11
chr3_31582540_31582764 0.19 STT3B
 STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
 8370
 0.31
chr15_64719372_64719525 0.19 TRIP4
 thyroid hormone receptor interactor 4
 3134
 0.15
chr7_38406396_38406561 0.19 AMPH
 amphiphysin
 96235
 0.09
chr2_182043280_182043557 0.19 ENSG00000266705
 .
 126961
 0.06
chr17_62197840_62198235 0.19 ERN1
 endoplasmic reticulum to nucleus signaling 1
 9448
 0.16
chr6_11543816_11543967 0.19 TMEM170B
 transmembrane protein 170B
 5380
 0.28
chr10_111790590_111790741 0.18 ADD3
 adducin 3 (gamma)
 22943
 0.19
chr2_169031648_169031799 0.18 STK39
 serine threonine kinase 39
 72928
 0.13
chr10_7234387_7234631 0.18 SFMBT2
 Scm-like with four mbt domains 2
 216198
 0.02
chr10_87374502_87374653 0.18 RP11-93H12.2
9427
 0.22
chr21_36388198_36388378 0.18 RUNX1
 runt-related transcription factor 1
 33174
 0.25
chrX_39881532_39881925 0.18 BCOR
 BCL6 corepressor
 40462
 0.22
chr18_46311537_46311688 0.18 RP11-484L8.1
49529
 0.15
chr12_56496732_56496913 0.18 PA2G4
 proliferation-associated 2G4, 38kDa
 1281
 0.18
chr5_156682934_156683085 0.18 CYFIP2
 cytoplasmic FMR1 interacting protein 2
 10082
 0.13
chr7_5461177_5461902 0.18 TNRC18
 trinucleotide repeat containing 18
 1638
 0.24
chr6_24979806_24979981 0.17 FAM65B
 family with sequence similarity 65, member B
 43705
 0.14
chr7_143134529_143134813 0.17 TAS2R60
 taste receptor, type 2, member 60
 5875
 0.14
chr6_4906933_4907084 0.17 CDYL
 chromodomain protein, Y-like
 16782
 0.25
chr15_96212893_96213044 0.17 ENSG00000222076
 .
 76065
 0.13
chr12_10034054_10034205 0.17 KLRF2
 killer cell lectin-like receptor subfamily F, member 2
 41
 0.97
chr6_20379695_20379857 0.17 E2F3
 E2F transcription factor 3
 22622
 0.16
chr3_36942506_36942657 0.17 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 42207
 0.15
chr18_2639736_2639903 0.17 ENSG00000200875
 .
 10047
 0.14
chr5_173330841_173330992 0.17 CPEB4
 cytoplasmic polyadenylation element binding protein 4
 10835
 0.26
chr1_184860081_184860278 0.17 ENSG00000252222
 .
 69556
 0.11
chr3_151929138_151929289 0.17 MBNL1
 muscleblind-like splicing regulator 1
 56616
 0.14
chr1_33093196_33093400 0.17 ENSG00000200591
 .
 12254
 0.15
chr12_120486076_120486227 0.17 ENSG00000272464
 .
 83
 0.97
chr6_152619759_152619910 0.17 SYNE1
 spectrin repeat containing, nuclear envelope 1
 3424
 0.33
chr14_50803097_50803405 0.17 CDKL1
 cyclin-dependent kinase-like 1 (CDC2-related kinase)
 2496
 0.24
chr5_80052614_80052958 0.17 DHFR
 dihydrofolate reductase
 101984
 0.06
chr1_62905621_62905864 0.17 USP1
 ubiquitin specific peptidase 1
 3416
 0.33
chr3_18472080_18472368 0.17 SATB1
 SATB homeobox 1
 4521
 0.24
chr2_176344494_176344645 0.17 ENSG00000221347
 .
 149468
 0.04
chr13_77928416_77928623 0.17 MYCBP2
 MYC binding protein 2, E3 ubiquitin protein ligase
 27340
 0.25
chr3_73101509_73101660 0.17 EBLN2
 endogenous Bornavirus-like nucleoprotein 2
 9226
 0.15
chr6_139601830_139602039 0.16 RP11-445F6.2
2310
 0.31
chr4_169240715_169240866 0.16 DDX60
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
 832
 0.66
chr2_109182452_109182603 0.16 LIMS1
 LIM and senescent cell antigen-like domains 1
 22240
 0.2
chr14_51253681_51254112 0.16 NIN
 ninein (GSK3B interacting protein)
 20383
 0.15
chr6_130462311_130462462 0.16 RP11-73O6.3
1586
 0.46
chr3_3191492_3191643 0.16 RP11-97C16.1
3059
 0.22
chr4_108940297_108940448 0.16 HADH
 hydroxyacyl-CoA dehydrogenase
 14581
 0.2
chr1_169659993_169660655 0.16 SELL
 selectin L
 20515
 0.18
chr4_154449272_154449464 0.16 KIAA0922
 KIAA0922
 27680
 0.22
chr12_104860037_104860188 0.16 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 9333
 0.28
chr4_4860648_4860832 0.16 MSX1
 msh homeobox 1
 653
 0.8
chr1_24843935_24844086 0.16 RCAN3
 RCAN family member 3
 3147
 0.22
chr3_128896354_128896666 0.16 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 6232
 0.14
chr19_41813267_41813681 0.16 CCDC97
 coiled-coil domain containing 97
 2620
 0.16
chr9_20573912_20574063 0.16 ENSG00000252324
 .
 2229
 0.34
chr2_148642523_148642674 0.16 ENSG00000212389
 .
 7607
 0.19
chr1_90194035_90194243 0.16 ENSG00000239176
 .
 39738
 0.15
chr1_24750479_24750630 0.16 NIPAL3
 NIPA-like domain containing 3
 4516
 0.2
chr2_84766841_84767171 0.15 DNAH6
 dynein, axonemal, heavy chain 6
 22063
 0.25
chrX_1636298_1636735 0.15 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 19484
 0.19
chrX_77181441_77181592 0.15 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
 15317
 0.15
chr2_61410565_61410716 0.15 AHSA2
 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
 1207
 0.43
chr17_45912395_45912546 0.15 LRRC46
 leucine rich repeat containing 46
 3477
 0.13
chr11_13308415_13308691 0.15 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 9121
 0.28
chr1_10562561_10562712 0.15 PEX14
 peroxisomal biogenesis factor 14
 27597
 0.11
chr6_13436217_13436368 0.15 GFOD1
 glucose-fructose oxidoreductase domain containing 1
 27923
 0.16
chr2_180273986_180274137 0.15 SESTD1
 SEC14 and spectrin domains 1
 144544
 0.05
chr9_95060115_95060318 0.15 IARS
 isoleucyl-tRNA synthetase
 4178
 0.18
chr12_120561416_120561689 0.15 RAB35
 RAB35, member RAS oncogene family
 6909
 0.15
chr2_11640982_11641233 0.15 ENSG00000201610
 .
 16416
 0.12
chr3_72806276_72806532 0.15 ENSG00000222838
 .
 65442
 0.12
chr7_45958414_45958565 0.15 IGFBP3
 insulin-like growth factor binding protein 3
 1464
 0.42
chr1_167479935_167480086 0.15 CD247
 CD247 molecule
 7765
 0.21
chr12_93830493_93830644 0.15 UBE2N
 ubiquitin-conjugating enzyme E2N
 4464
 0.18
chr2_119599709_119600100 0.15 EN1
 engrailed homeobox 1
 5350
 0.31
chr5_35904649_35904800 0.15 IL7R
 interleukin 7 receptor
 29208
 0.14
chr1_31220295_31220566 0.15 ENSG00000264773
 .
 8351
 0.16
chr7_139435748_139435899 0.15 HIPK2
 homeodomain interacting protein kinase 2
 13982
 0.24
chr10_105665817_105666089 0.15 OBFC1
 oligonucleotide/oligosaccharide-binding fold containing 1
 11474
 0.17
chr15_91294132_91294283 0.15 ENSG00000200677
 .
 4335
 0.18
chr20_49543758_49543983 0.15 ADNP
 activity-dependent neuroprotector homeobox
 1483
 0.3
chrX_64943543_64943694 0.15 MSN
 moesin
 56081
 0.17
chr6_139632741_139632892 0.15 TXLNB
 taxilin beta
 19540
 0.19
chr4_154446377_154446528 0.15 KIAA0922
 KIAA0922
 30596
 0.21
chr2_120802527_120802678 0.15 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
 25941
 0.22
chr4_111436373_111436524 0.15 RP11-380D23.1
4213
 0.28
chr2_69835709_69835860 0.15 AAK1
 AP2 associated kinase 1
 35002
 0.16
chr13_42895024_42895175 0.14 AKAP11
 A kinase (PRKA) anchor protein 11
 48810
 0.18
chr7_21521163_21521314 0.14 ENSG00000221783
 .
 10562
 0.22
chr7_3084950_3085101 0.14 CARD11
 caspase recruitment domain family, member 11
 1446
 0.5
chr12_59809030_59809181 0.14 ENSG00000251931
 .
 35448
 0.17
chr5_109367383_109367564 0.14 AC011366.3
 Uncharacterized protein
 148590
 0.05
chr4_26398607_26398882 0.14 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 31598
 0.23
chr12_40076320_40076676 0.14 C12orf40
 chromosome 12 open reading frame 40
 56513
 0.14
chrX_19664911_19665062 0.14 SH3KBP1
 SH3-domain kinase binding protein 1
 23494
 0.26
chr9_115065190_115065341 0.14 PTBP3
 polypyrimidine tract binding protein 3
 29858
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of IRF9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.3 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation