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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for IRX2

Z-value: 2.53

Motif logo

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.8 iroquois homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_2739330_2739481IRX2123640.244694-0.771.5e-02Click!
chr5_2739627_2739778IRX2120670.245219-0.442.4e-01Click!
chr5_2750173_2750324IRX215210.4127720.294.6e-01Click!

Activity of the IRX2 motif across conditions

Conditions sorted by the z-value of the IRX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_106383531_106383975 0.59 NCK2
 NCK adaptor protein 2
 21565
 0.26
chr3_154867378_154867529 0.53 MME-AS1
 MME antisense RNA 1
 33621
 0.22
chr4_25845411_25845804 0.52 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
 16646
 0.24
chr16_67718722_67719015 0.51 C16orf86
 chromosome 16 open reading frame 86
 18075
 0.09
chr5_168842640_168842791 0.48 SLIT3
 slit homolog 3 (Drosophila)
 114582
 0.06
chr2_36757574_36758239 0.44 RP11-78I14.1
17031
 0.17
chr21_36330048_36330210 0.43 RUNX1
 runt-related transcription factor 1
 68042
 0.14
chr8_108684494_108684645 0.42 ANGPT1
 angiopoietin 1
 174286
 0.03
chr6_169890374_169890525 0.41 WDR27
 WD repeat domain 27
 170339
 0.03
chr12_14539508_14539659 0.41 ATF7IP
 activating transcription factor 7 interacting protein
 1585
 0.47
chr19_16478953_16479699 0.41 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 6562
 0.16
chr1_52076976_52077127 0.40 OSBPL9
 oxysterol binding protein-like 9
 5496
 0.23
chr5_55498484_55498698 0.39 ANKRD55
 ankyrin repeat domain 55
 30162
 0.16
chr3_16889716_16889867 0.39 PLCL2
 phospholipase C-like 2
 36661
 0.2
chr2_223434159_223434310 0.39 RP11-16P6.1
204
 0.96
chr20_48203946_48204097 0.39 ENSG00000265225
 .
 803
 0.67
chr20_2820395_2820814 0.38 PCED1A
 PC-esterase domain containing 1A
 713
 0.38
chr13_99933650_99933945 0.37 GPR18
 G protein-coupled receptor 18
 19799
 0.17
chr1_220950327_220950478 0.37 MARC1
 mitochondrial amidoxime reducing component 1
 9699
 0.19
chr6_135040752_135041042 0.36 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
 209402
 0.02
chr2_46665689_46665843 0.36 ENSG00000241791
 .
 9884
 0.2
chr2_198127644_198128365 0.36 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 39239
 0.13
chr7_47705936_47706228 0.36 C7orf65
 chromosome 7 open reading frame 65
 11240
 0.26
chr7_7712444_7712595 0.36 RPA3
 replication protein A3, 14kDa
 31916
 0.21
chr12_81326738_81326889 0.35 ENSG00000208022
 .
 2799
 0.24
chr1_15480447_15481131 0.35 TMEM51
 transmembrane protein 51
 504
 0.82
chr4_86757167_86757466 0.35 ARHGAP24
 Rho GTPase activating protein 24
 8270
 0.28
chr10_95274846_95275177 0.35 ENSG00000212396
 .
 4574
 0.19
chr1_114324657_114324917 0.34 PHTF1
 putative homeodomain transcription factor 1
 22689
 0.15
chr2_162807979_162808245 0.34 ENSG00000253046
 .
 32820
 0.21
chr2_145253384_145253620 0.34 ZEB2
 zinc finger E-box binding homeobox 2
 21613
 0.22
chr13_45895503_45895692 0.34 ENSG00000253051
 .
 14985
 0.11
chr4_111096983_111097134 0.34 ELOVL6
 ELOVL fatty acid elongase 6
 22751
 0.22
chr7_100397045_100397346 0.33 ENSG00000263672
 .
 21691
 0.1
chr6_107645107_107645353 0.33 PDSS2
 prenyl (decaprenyl) diphosphate synthase, subunit 2
 111867
 0.06
chr6_122329889_122330040 0.33 ENSG00000199932
 .
 202830
 0.03
chr1_78721233_78721384 0.33 ENSG00000237413
 .
 26002
 0.2
chr15_99489885_99490412 0.33 IGF1R
 insulin-like growth factor 1 receptor
 22319
 0.19
chr9_123200598_123200791 0.33 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
 9656
 0.31
chr4_86727557_86727760 0.33 ARHGAP24
 Rho GTPase activating protein 24
 21240
 0.24
chr3_153345455_153345756 0.32 ENSG00000200162
 .
 20439
 0.26
chr10_7088660_7089557 0.32 SFMBT2
 Scm-like with four mbt domains 2
 361599
 0.01
chr4_86595083_86595234 0.32 ENSG00000266421
 .
 48463
 0.17
chr2_198123616_198124373 0.32 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 43249
 0.13
chr2_63890050_63890201 0.32 ENSG00000221085
 .
 32544
 0.2
chr9_77762259_77762961 0.32 ENSG00000200041
 .
 33927
 0.15
chr11_118097693_118098499 0.31 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 2287
 0.23
chr1_110415768_110416011 0.31 RP11-195M16.1
12997
 0.17
chr1_9739584_9739800 0.31 RP11-558F24.4
7921
 0.18
chr1_65387999_65388150 0.31 JAK1
 Janus kinase 1
 44113
 0.17
chr8_8718009_8718517 0.31 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 32892
 0.17
chr8_59492254_59492405 0.31 SDCBP
 syndecan binding protein (syntenin)
 14754
 0.24
chr2_68597035_68597533 0.31 AC015969.3
4568
 0.19
chr2_55518720_55518871 0.31 ENSG00000206964
 .
 5641
 0.15
chr9_221181_221359 0.31 C9orf66
 chromosome 9 open reading frame 66
 5377
 0.19
chr3_131563587_131563738 0.30 CPNE4
 copine IV
 80763
 0.11
chr19_7733657_7733953 0.30 RETN
 resistin
 125
 0.91
chr11_33302196_33302347 0.30 HIPK3
 homeodomain interacting protein kinase 3
 22394
 0.2
chr10_6322222_6322373 0.30 ENSG00000238366
 .
 34503
 0.15
chr3_108021242_108021538 0.30 HHLA2
 HERV-H LTR-associating 2
 58
 0.98
chr1_33723200_33724119 0.30 ZNF362
 zinc finger protein 362
 1485
 0.38
chr10_102669234_102669601 0.30 ENSG00000222072
 .
 2380
 0.18
chr21_39190684_39190863 0.30 KCNJ6
 potassium inwardly-rectifying channel, subfamily J, member 6
 94784
 0.08
chr5_111304224_111304663 0.29 NREP-AS1
 NREP antisense RNA 1
 706
 0.74
chr2_98343204_98343355 0.29 ZAP70
 zeta-chain (TCR) associated protein kinase 70kDa
 1946
 0.32
chr6_87910032_87910183 0.29 ZNF292
 zinc finger protein 292
 33135
 0.16
chr15_80271357_80271985 0.29 BCL2A1
 BCL2-related protein A1
 7883
 0.2
chr7_151122661_151122812 0.29 RP4-555L14.4
2033
 0.2
chr3_113831548_113831699 0.29 QTRTD1
 queuine tRNA-ribosyltransferase domain containing 1
 30007
 0.17
chr12_78398855_78399006 0.29 NAV3
 neuron navigator 3
 38874
 0.22
chr16_73200279_73201088 0.29 C16orf47
 chromosome 16 open reading frame 47
 22337
 0.26
chr5_75395327_75395609 0.29 ENSG00000252833
 .
 7842
 0.25
chr4_78003999_78004150 0.29 CCNI
 cyclin I
 6916
 0.24
chr3_140938122_140938273 0.29 ACPL2
 acid phosphatase-like 2
 9371
 0.27
chr10_97552518_97552961 0.29 ENTPD1
 ectonucleoside triphosphate diphosphohydrolase 1
 37025
 0.15
chr11_43772662_43772813 0.28 HSD17B12
 hydroxysteroid (17-beta) dehydrogenase 12
 70406
 0.1
chr8_134541719_134541989 0.28 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 30228
 0.24
chr2_54657078_54657582 0.28 SPTBN1
 spectrin, beta, non-erythrocytic 1
 26092
 0.22
chr8_128836786_128836937 0.28 ENSG00000249859
 .
 28653
 0.21
chr2_145137951_145138102 0.28 GTDC1
 glycosyltransferase-like domain containing 1
 47943
 0.16
chr2_136689063_136689371 0.28 DARS
 aspartyl-tRNA synthetase
 11094
 0.21
chr2_42473364_42473515 0.28 EML4
 echinoderm microtubule associated protein like 4
 54954
 0.14
chr2_228356582_228356746 0.28 AGFG1
 ArfGAP with FG repeats 1
 16324
 0.2
chr9_138981710_138981861 0.28 NACC2
 NACC family member 2, BEN and BTB (POZ) domain containing
 5346
 0.22
chr15_39626996_39627182 0.28 RP11-624L4.1
61005
 0.14
chr2_161442081_161442232 0.28 RBMS1
 RNA binding motif, single stranded interacting protein 1
 91851
 0.09
chr4_153466291_153466442 0.28 ENSG00000268471
 .
 8786
 0.2
chr11_108102757_108102978 0.28 ENSG00000206967
 .
 2536
 0.23
chr12_70376087_70376238 0.28 RP11-611E13.3
35301
 0.19
chr2_28352746_28352897 0.28 ENSG00000265321
 .
 133587
 0.05
chr13_50795355_50795506 0.28 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 139123
 0.04
chr3_12509546_12509697 0.28 TSEN2
 TSEN2 tRNA splicing endonuclease subunit
 16310
 0.16
chr1_221488124_221488275 0.28 DUSP10
 dual specificity phosphatase 10
 422603
 0.01
chr15_78361706_78361921 0.28 TBC1D2B
 TBC1 domain family, member 2B
 3348
 0.17
chr1_185298763_185298914 0.27 IVNS1ABP
 influenza virus NS1A binding protein
 12377
 0.22
chr6_24979166_24979784 0.27 FAM65B
 family with sequence similarity 65, member B
 43287
 0.14
chr7_27964371_27964522 0.27 ENSG00000265382
 .
 44340
 0.16
chr2_32296061_32296212 0.27 SPAST
 spastin
 7360
 0.17
chr1_66839472_66840219 0.27 PDE4B
 phosphodiesterase 4B, cAMP-specific
 19780
 0.27
chr10_64379208_64379359 0.27 ZNF365
 zinc finger protein 365
 24250
 0.22
chr1_231015041_231015192 0.27 RP5-858B6.3
4524
 0.14
chr10_11336975_11337126 0.27 CELF2-AS1
 CELF2 antisense RNA 1
 24797
 0.24
chr9_117768493_117768791 0.27 TNC
 tenascin C
 58549
 0.14
chr15_82496446_82496597 0.27 ENSG00000212170
 .
 29795
 0.15
chr4_85836939_85837233 0.27 ENSG00000252062
 .
 29447
 0.21
chr3_152215781_152215932 0.27 RP11-362A9.3
1254
 0.56
chr8_121760612_121760811 0.27 RP11-713M15.1
12782
 0.25
chr2_113944482_113944729 0.27 PSD4
 pleckstrin and Sec7 domain containing 4
 9252
 0.14
chr7_127998275_127998426 0.27 PRRT4
 proline-rich transmembrane protein 4
 1339
 0.36
chr21_36346755_36347126 0.27 RUNX1
 runt-related transcription factor 1
 74522
 0.13
chr15_86123833_86124949 0.27 RP11-815J21.2
982
 0.53
chr6_109201302_109201453 0.27 ARMC2
 armadillo repeat containing 2
 11196
 0.24
chr12_22383122_22383273 0.27 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 18783
 0.23
chr2_38798588_38798739 0.27 HNRNPLL
 heterogeneous nuclear ribonucleoprotein L-like
 1685
 0.41
chr6_14700888_14701039 0.27 ENSG00000206960
 .
 54197
 0.18
chr9_75775412_75775563 0.27 ANXA1
 annexin A1
 2917
 0.38
chr11_59016128_59016425 0.26 ENSG00000263999
 .
 34104
 0.13
chr3_182428407_182428558 0.26 RP11-225N10.1
82700
 0.1
chr20_47629406_47629557 0.26 RP1-155G6.4
33100
 0.17
chr1_92017582_92017733 0.26 CDC7
 cell division cycle 7
 50962
 0.18
chr7_155515211_155515362 0.26 RBM33
 RNA binding motif protein 33
 21701
 0.22
chr10_112651307_112651546 0.26 ENSG00000265827
 .
 6422
 0.14
chr15_39866169_39866433 0.26 THBS1
 thrombospondin 1
 6979
 0.21
chr10_104890869_104891020 0.26 NT5C2
 5'-nucleotidase, cytosolic II
 22440
 0.21
chr8_67055451_67055668 0.26 TRIM55
 tripartite motif containing 55
 16281
 0.23
chr22_22209971_22210122 0.26 MAPK1
 mitogen-activated protein kinase 1
 11684
 0.15
chr2_23927928_23928079 0.26 KLHL29
 kelch-like family member 29
 62741
 0.13
chr1_21385882_21386033 0.26 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 8470
 0.26
chr6_139836821_139836972 0.26 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 141139
 0.05
chrX_109200589_109200740 0.26 TMEM164
 transmembrane protein 164
 45199
 0.18
chr2_237858362_237858513 0.26 ENSG00000202341
 .
 65511
 0.12
chr8_61925125_61925700 0.26 CLVS1
 clavesin 1
 44305
 0.2
chr6_109560238_109560680 0.26 ENSG00000238474
 .
 52102
 0.12
chr1_20902306_20902457 0.26 CDA
 cytidine deaminase
 13060
 0.17
chr8_134562977_134563358 0.26 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 20925
 0.27
chr5_168553589_168553740 0.26 CTB-174D11.1
96221
 0.08
chr6_138027696_138027847 0.26 ENSG00000216097
 .
 10314
 0.27
chr17_61502956_61503238 0.26 RP11-269G24.3
5353
 0.14
chr2_225850813_225850964 0.26 ENSG00000263828
 .
 24369
 0.23
chr5_101618511_101618782 0.26 SLCO4C1
 solute carrier organic anion transporter family, member 4C1
 13607
 0.2
chr6_16404477_16404628 0.26 ENSG00000265642
 .
 24202
 0.26
chr1_35920565_35920716 0.26 KIAA0319L
 KIAA0319-like
 332
 0.89
chr5_148801935_148802347 0.26 ENSG00000208035
 .
 6340
 0.15
chr3_112456089_112456520 0.26 ENSG00000242770
 .
 65021
 0.11
chr5_8727783_8727934 0.26 ENSG00000247516
 .
 266820
 0.02
chr12_82337130_82337312 0.26 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
 183889
 0.03
chr7_138604637_138604804 0.26 KIAA1549
 KIAA1549
 499
 0.84
chr17_79483461_79484043 0.26 ACTG1
 actin, gamma 1
 2086
 0.16
chr7_125726_125877 0.26 FAM20C
 family with sequence similarity 20, member C
 67168
 0.12
chr6_45452002_45452153 0.25 RUNX2
 runt-related transcription factor 2
 61855
 0.13
chr2_128406747_128407440 0.25 GPR17
 G protein-coupled receptor 17
 421
 0.7
chr15_68499988_68500218 0.25 CALML4
 calmodulin-like 4
 1686
 0.33
chr6_111025543_111025694 0.25 ENSG00000200522
 .
 17933
 0.22
chr20_35570220_35570403 0.25 SAMHD1
 SAM domain and HD domain 1
 9800
 0.21
chr12_13154703_13155247 0.25 HEBP1
 heme binding protein 1
 1768
 0.27
chr20_58807824_58807975 0.25 ENSG00000207802
 .
 75633
 0.12
chr11_19130331_19130482 0.25 ZDHHC13
 zinc finger, DHHC-type containing 13
 8270
 0.22
chr3_81802908_81803078 0.25 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 8319
 0.34
chr1_29388426_29388715 0.25 TMEM200B
 transmembrane protein 200B
 60443
 0.1
chr7_114857333_114857484 0.25 ENSG00000199764
 .
 9358
 0.33
chr16_4050021_4050172 0.25 ADCY9
 adenylate cyclase 9
 11095
 0.18
chr3_151916865_151917016 0.25 MBNL1
 muscleblind-like splicing regulator 1
 68889
 0.12
chr4_153392019_153392170 0.25 ENSG00000264678
 .
 18474
 0.21
chr7_106063817_106063968 0.25 CTB-111H14.1
81393
 0.1
chr10_3816114_3816265 0.25 RP11-184A2.2
6082
 0.22
chr6_10413127_10413925 0.25 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
 414
 0.77
chr3_72060973_72061124 0.25 ENSG00000239250
 .
 184720
 0.03
chr2_204303722_204303873 0.25 ABI2
 abl-interactor 2
 48030
 0.15
chr19_41332938_41333153 0.25 EGLN2
 egl-9 family hypoxia-inducible factor 2
 19897
 0.11
chr2_190017847_190017998 0.25 ENSG00000264725
 .
 20085
 0.19
chr11_70261652_70262194 0.24 CTTN
 cortactin
 4308
 0.17
chr1_236006258_236006409 0.24 LYST-AS1
 LYST antisense RNA 1
 3550
 0.2
chr2_143922793_143923037 0.24 RP11-190J23.1
6826
 0.27
chr10_73514684_73515259 0.24 C10orf54
 chromosome 10 open reading frame 54
 2416
 0.29
chr14_35152571_35152722 0.24 ENSG00000253003
 .
 7549
 0.2
chr1_203158968_203159119 0.24 CHI3L1
 chitinase 3-like 1 (cartilage glycoprotein-39)
 3166
 0.19
chr3_187605321_187605472 0.24 BCL6
 B-cell CLL/lymphoma 6
 141881
 0.05
chr11_13358056_13358317 0.24 ENSG00000222162
 .
 16569
 0.22
chr16_81531821_81532117 0.24 CMIP
 c-Maf inducing protein
 3015
 0.36
chr15_86245685_86246263 0.24 RP11-815J21.1
1634
 0.25
chr1_200337779_200337983 0.24 ZNF281
 zinc finger protein 281
 41239
 0.21
chr12_80295001_80295152 0.24 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 12615
 0.18
chr5_49850280_49850431 0.24 PARP8
 poly (ADP-ribose) polymerase family, member 8
 111378
 0.07
chrX_77194022_77194173 0.24 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
 27898
 0.14
chr2_98171418_98171569 0.24 ANKRD36B
 ankyrin repeat domain 36B
 10353
 0.2
chrX_13096464_13097003 0.24 FAM9C
 family with sequence similarity 9, member C
 33932
 0.21
chr6_97667926_97668077 0.24 MMS22L
 MMS22-like, DNA repair protein
 43227
 0.21
chr7_37026279_37026430 0.24 ELMO1
 engulfment and cell motility 1
 240
 0.94
chr11_47276308_47276801 0.24 NR1H3
 nuclear receptor subfamily 1, group H, member 3
 2601
 0.15
chr2_136734580_136734731 0.24 AC093391.2
8091
 0.21
chr20_40110976_40111127 0.24 CHD6
 chromodomain helicase DNA binding protein 6
 16906
 0.25
chr5_171325858_171326009 0.24 FBXW11
 F-box and WD repeat domain containing 11
 78827
 0.09
chr17_65516947_65517209 0.24 CTD-2653B5.1
3519
 0.24
chr5_129906760_129906911 0.24 ENSG00000252514
 .
 184462
 0.03
chr9_117094142_117094333 0.24 ORM2
 orosomucoid 2
 2085
 0.3
chr3_105626614_105626964 0.24 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 38393
 0.24
chr11_67973501_67973746 0.24 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
 6598
 0.21
chr12_32676345_32676560 0.24 FGD4
 FYVE, RhoGEF and PH domain containing 4
 10806
 0.25
chr7_76823195_76823489 0.24 FGL2
 fibrinogen-like 2
 5801
 0.24
chr7_82305530_82305681 0.24 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 232491
 0.02

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.3 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0031297 replication fork processing(GO:0031297)
0.1 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.2 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.1 GO:0002666 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.3 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.2 GO:0015825 L-serine transport(GO:0015825)
0.1 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.5 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0052556 positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.0 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0035929 steroid hormone secretion(GO:0035929) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0036315 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:2000188 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.1 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.4 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.0 GO:0002016 regulation of blood volume by renin-angiotensin(GO:0002016)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0051647 establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084)
0.0 0.2 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0048892 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.0 GO:0044273 sulfur amino acid catabolic process(GO:0000098) sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.1 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0050764 regulation of phagocytosis(GO:0050764) positive regulation of phagocytosis(GO:0050766)
0.0 0.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0046189 phenol-containing compound biosynthetic process(GO:0046189)
0.0 0.0 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0098764 meiosis I cell cycle phase(GO:0098764)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.0 GO:0048148 behavioral response to cocaine(GO:0048148)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0000805 X chromosome(GO:0000805)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.1 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions