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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for IRX5

Z-value: 0.85

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Transcription factors associated with IRX5

Gene Symbol	Gene ID	Gene Info
IRX5 Ensembl NCBI GeneCards UniProt	ENSG00000176842.10	iroquois homeobox 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_54966944_54967095	IRX5	1035	0.704780	0.80	8.9e-03	Click!
chr16_54955186_54955337	IRX5	9513	0.322537	-0.79	1.2e-02	Click!
chr16_55011040_55011191	IRX5	45131	0.204986	0.78	1.3e-02	Click!
chr16_54964705_54964856	IRX5	6	0.989431	0.73	2.6e-02	Click!
chr16_54962416_54962653	IRX5	2240	0.469381	0.69	3.8e-02	Click!

Activity of the IRX5 motif across conditions

Conditions sorted by the z-value of the IRX5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_61193206_61193983	0.49	ENSG00000222251	.	32293	0.14
chr13_99940999_99941164	0.41	GPR183	G protein-coupled receptor 183	18578	0.18
chr5_32711536_32711687	0.39	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	71	0.98
chr22_19463070_19463221	0.38	UFD1L	ubiquitin fusion degradation 1 like (yeast)	3309	0.13
chr12_95875168_95875319	0.37	METAP2	methionyl aminopeptidase 2	3327	0.26
chr4_48633627_48633778	0.36	FRYL	FRY-like	2725	0.35
chr3_136638222_136638692	0.34	NCK1	NCK adaptor protein 1	8424	0.2
chr1_111209754_111210001	0.34	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	7778	0.18
chr13_80443621_80443990	0.34	NDFIP2	Nedd4 family interacting protein 2	388217	0.01
chr11_130819091_130819698	0.34	SNX19	sorting nexin 19	32990	0.21
chr15_64566939_64567224	0.33	ENSG00000252774	.	67657	0.08
chr5_86377835_86378358	0.32	ENSG00000251951	.	20567	0.22
chr7_98975533_98975728	0.31	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	3277	0.16
chr4_36325181_36325757	0.31	DTHD1	death domain containing 1	39825	0.17
chr2_99377617_99378126	0.29	ENSG00000201070	.	21002	0.19
chr3_193306986_193307190	0.29	OPA1	optic atrophy 1 (autosomal dominant)	3845	0.21
chr7_135655824_135656276	0.29	MTPN	myotrophin	6014	0.18
chr10_63660538_63660964	0.29	ARID5B	AT rich interactive domain 5B (MRF1-like)	308	0.93
chr2_211287515_211287666	0.29	LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)	17879	0.2
chr15_92393961_92394196	0.29	SLCO3A1	solute carrier organic anion transporter family, member 3A1	2847	0.34
chr11_102336511_102336743	0.29	RP11-315O6.2	HCG1815860; Uncharacterized protein	1359	0.39
chr20_4647902_4648185	0.29	PRNP	prion protein	18839	0.22
chr12_4377862_4378162	0.29	CCND2	cyclin D2	4926	0.19
chrX_30675313_30675506	0.29	GK	glycerol kinase	3754	0.23
chr9_82288636_82288787	0.28	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	21203	0.3
chr21_16047747_16048186	0.28	AF165138.7	Protein LOC388813	16824	0.25
chr2_227557731_227557882	0.28	ENSG00000263363	.	34297	0.21
chr1_172508682_172508833	0.28	SUCO	SUN domain containing ossification factor	6400	0.25
chr1_100911854_100912179	0.28	RP5-837M10.4		39537	0.15
chr13_50144464_50144942	0.28	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	3244	0.28
chr2_142256928_142257196	0.27	ENSG00000265224	.	139351	0.05
chr10_76887465_76887630	0.27	SAMD8	sterile alpha motif domain containing 8	16080	0.16
chr10_130991417_130991568	0.27	MGMT	O-6-methylguanine-DNA methyltransferase	273956	0.02
chrX_18541587_18541738	0.27	CDKL5	cyclin-dependent kinase-like 5	81354	0.1
chr11_77159663_77159814	0.26	DKFZP434E1119		24678	0.18
chr14_103869448_103869637	0.26	MARK3	MAP/microtubule affinity-regulating kinase 3	16966	0.16
chr4_26287690_26287841	0.26	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	13536	0.3
chr3_71482056_71482445	0.26	ENSG00000221264	.	108990	0.07
chr2_68968807_68969362	0.26	ARHGAP25	Rho GTPase activating protein 25	7070	0.26
chr2_172019818_172019981	0.26	TLK1	tousled-like kinase 1	2489	0.34
chr15_55548229_55548380	0.26	RAB27A	RAB27A, member RAS oncogene family	7071	0.22
chr8_104312792_104312943	0.26	FZD6	frizzled family receptor 6	1763	0.28
chr15_35797240_35797391	0.26	DPH6	diphthamine biosynthesis 6	41051	0.22
chr1_9819815_9819984	0.26	CLSTN1	calsyntenin 1	8260	0.19
chr18_51701283_51701434	0.26	ENSG00000207233	.	47424	0.14
chr4_99070431_99070582	0.26	STPG2	sperm-tail PG-rich repeat containing 2	6115	0.25
chr13_77764490_77764641	0.25	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	102916	0.07
chr7_45061484_45061635	0.25	CCM2	cerebral cavernous malformation 2	5066	0.16
chr1_100817300_100817579	0.25	CDC14A	cell division cycle 14A	149	0.96
chr2_51298193_51298422	0.25	NRXN1	neurexin 1	38633	0.21
chr12_41008563_41008793	0.25	ENSG00000207492	.	60609	0.13
chr6_146133782_146134299	0.25	FBXO30	F-box protein 30	1849	0.32
chr6_85235911_85236062	0.25	RP11-132M7.3		163157	0.04
chr4_159747787_159747983	0.25	FNIP2	folliculin interacting protein 2	5347	0.24
chr14_35306923_35307074	0.25	ENSG00000251726	.	7568	0.17
chr17_8837985_8838341	0.25	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	22329	0.21
chr13_47310379_47310530	0.25	ESD	esterase D	45249	0.16
chr7_104986020_104986245	0.25	ENSG00000201179	.	12895	0.21
chr1_111328783_111328934	0.25	ENSG00000199710	.	21730	0.2
chr7_133296572_133296723	0.24	EXOC4	exocyst complex component 4	35431	0.24
chrX_78205440_78205812	0.24	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	4708	0.36
chr6_24926578_24926819	0.24	FAM65B	family with sequence similarity 65, member B	9490	0.23
chr7_150374566_150375043	0.24	GIMAP2	GTPase, IMAP family member 2	7984	0.18
chr7_44454046_44454197	0.24	NUDCD3	NudC domain containing 3	76358	0.08
chr3_182982074_182982426	0.24	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	840	0.63
chr2_102633330_102633593	0.24	IL1R2	interleukin 1 receptor, type II	8484	0.25
chr1_108453036_108453329	0.24	VAV3-AS1	VAV3 antisense RNA 1	53883	0.14
chr12_76424687_76424881	0.24	RP11-290L1.3		510	0.51
chr2_206947860_206948145	0.24	INO80D	INO80 complex subunit D	2904	0.22
chrX_55743062_55743213	0.24	RRAGB	Ras-related GTP binding B	1035	0.62
chrX_135654487_135654782	0.24	ENSG00000199424	.	660	0.63
chr21_19149638_19149873	0.23	AL109761.5		16050	0.22
chr22_41124299_41124484	0.23	MCHR1	melanin-concentrating hormone receptor 1	49114	0.11
chr15_94749124_94749278	0.23	MCTP2	multiple C2 domains, transmembrane 2	25566	0.27
chr6_6788347_6788498	0.23	ENSG00000240936	.	150708	0.04
chr11_118109730_118110277	0.23	MPZL3	myelin protein zero-like 3	13059	0.13
chr6_16682722_16682873	0.23	RP1-151F17.1		78572	0.11
chr14_91876524_91876913	0.23	CCDC88C	coiled-coil domain containing 88C	6972	0.25
chr7_76988894_76989045	0.23	GSAP	gamma-secretase activating protein	29285	0.2
chr20_20528793_20529061	0.23	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	35683	0.22
chr7_2934081_2934232	0.23	CARD11	caspase recruitment domain family, member 11	35538	0.16
chr3_15836947_15837338	0.23	ANKRD28	ankyrin repeat domain 28	886	0.63
chr15_101739782_101740269	0.23	CHSY1	chondroitin sulfate synthase 1	52112	0.12
chr2_39344551_39344947	0.23	SOS1	son of sevenless homolog 1 (Drosophila)	2842	0.24
chr3_109523115_109523342	0.23	ENSG00000265956	.	201553	0.03
chr6_130848690_130848841	0.23	ENSG00000202438	.	46492	0.17
chr16_57300569_57300908	0.23	PLLP	plasmolipin	3455	0.16
chr1_183451917_183452068	0.23	SMG7	SMG7 nonsense mediated mRNA decay factor	9925	0.21
chr7_105711713_105711864	0.23	SYPL1	synaptophysin-like 1	26520	0.22
chr6_109414712_109414966	0.23	SESN1	sestrin 1	1183	0.39
chr8_38226618_38226769	0.23	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	11646	0.12
chr1_117601173_117601556	0.23	RP11-27K13.3		748	0.55
chr11_67859558_67859709	0.23	CHKA	choline kinase alpha	28662	0.1
chr2_173301013_173301462	0.23	AC078883.4		7906	0.18
chr6_167320596_167320992	0.23	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	855	0.57
chr2_7070048_7070304	0.23	RNF144A	ring finger protein 144A	2998	0.26
chr7_101268981_101269132	0.22	MYL10	myosin, light chain 10, regulatory	3520	0.34
chr3_195908044_195908207	0.22	ENSG00000222335	.	21095	0.13
chr6_37243542_37243707	0.22	TBC1D22B	TBC1 domain family, member 22B	18076	0.15
chr17_43660361_43660725	0.22	RP11-798G7.4		24107	0.12
chr13_45553454_45553605	0.22	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	10089	0.18
chr10_7514092_7514414	0.22	ENSG00000207453	.	14518	0.24
chr8_96174564_96174728	0.22	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	28342	0.18
chr1_114378929_114379080	0.22	RP5-1073O3.2		12969	0.13
chr17_30838544_30838695	0.22	RP11-466A19.3		7352	0.11
chr6_13438217_13438450	0.22	GFOD1	glucose-fructose oxidoreductase domain containing 1	29964	0.15
chr9_123421951_123422208	0.22	MEGF9	multiple EGF-like-domains 9	54533	0.14
chr20_18487842_18487993	0.22	SEC23B	Sec23 homolog B (S. cerevisiae)	220	0.9
chr2_33674008_33674159	0.22	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	9030	0.28
chr2_113464747_113464898	0.22	NT5DC4	5'-nucleotidase domain containing 4	14241	0.18
chr1_108600076_108600227	0.22	ENSG00000264753	.	38758	0.18
chr6_41166873_41167272	0.22	TREML2	triggering receptor expressed on myeloid cells-like 2	1860	0.24
chr6_156601453_156601604	0.22	ENSG00000212295	.	98356	0.09
chr1_175139081_175139232	0.22	KIAA0040	KIAA0040	22734	0.22
chr4_100739336_100739595	0.22	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	1462	0.5
chr11_31531683_31531834	0.22	ELP4	elongator acetyltransferase complex subunit 4	433	0.57
chr8_130891988_130892139	0.22	ENSG00000200075	.	11101	0.21
chr12_14551868_14552176	0.22	ATF7IP	activating transcription factor 7 interacting protein	4225	0.29
chr7_111199944_111200095	0.22	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	1961	0.5
chr17_57716864_57717074	0.22	CLTC	clathrin, heavy chain (Hc)	19676	0.18
chr2_160461923_160462074	0.22	AC009506.1		9809	0.21
chr3_186650474_186650739	0.22	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	1465	0.43
chr8_130971634_130971785	0.21	FAM49B	family with sequence similarity 49, member B	11509	0.2
chr9_20322841_20323109	0.21	ENSG00000221744	.	27973	0.2
chr13_103501044_103501195	0.21	ERCC5	excision repair cross-complementing rodent repair deficiency, complementation group 5	2945	0.2
chr4_78775951_78776124	0.21	MRPL1	mitochondrial ribosomal protein L1	7637	0.27
chr12_9178784_9178989	0.21	RP11-259O18.4		29724	0.13
chr1_108327675_108328746	0.21	ENSG00000265536	.	9332	0.26
chr10_1100195_1100554	0.21	WDR37	WD repeat domain 37	1970	0.24
chr6_1610803_1611170	0.21	FOXC1	forkhead box C1	305	0.94
chr5_142258719_142258870	0.21	ARHGAP26-AS1	ARHGAP26 antisense RNA 1	10307	0.25
chr22_35461775_35461926	0.21	ISX	intestine-specific homeobox	279	0.93
chr13_100133813_100133964	0.21	LINC00449	long intergenic non-protein coding RNA 449	19418	0.15
chr4_477501_477652	0.21	ZNF721	zinc finger protein 721	9620	0.15
chr2_109231573_109232553	0.21	LIMS1	LIM and senescent cell antigen-like domains 1	5659	0.26
chr6_885485_885786	0.21	EXOC2	exocyst complex component 2	192518	0.03
chr17_40538812_40538963	0.21	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	1545	0.28
chr14_70121202_70121391	0.21	KIAA0247	KIAA0247	42983	0.16
chr14_61836268_61836532	0.21	PRKCH	protein kinase C, eta	8608	0.24
chr12_47663354_47663536	0.21	RP11-493L12.3		9359	0.22
chr6_90885829_90886103	0.21	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	120495	0.06
chr11_78438856_78439049	0.21	RP11-673F18.1		21343	0.21
chr5_112213241_112213518	0.21	ZRSR1	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1	13934	0.12
chr15_38942394_38942965	0.21	C15orf53	chromosome 15 open reading frame 53	46120	0.16
chr1_67395497_67395648	0.21	MIER1	mesoderm induction early response 1, transcriptional regulator	354	0.88
chr11_65272930_65273412	0.21	SCYL1	SCY1-like 1 (S. cerevisiae)	19377	0.1
chr12_11960380_11960661	0.21	ETV6	ets variant 6	55085	0.16
chrX_19697904_19698083	0.21	SH3KBP1	SH3-domain kinase binding protein 1	8877	0.31
chr19_7411370_7411784	0.21	CTB-133G6.1		2271	0.26
chr17_27103824_27103975	0.21	FAM222B	family with sequence similarity 222, member B	9777	0.07
chr1_174935228_174935449	0.21	RABGAP1L	RAB GTPase activating protein 1-like	1433	0.35
chr1_172441831_172441982	0.21	C1orf105	chromosome 1 open reading frame 105	19873	0.18
chr7_55709692_55709868	0.21	ENSG00000252857	.	43890	0.13
chr9_71458921_71459166	0.21	RP11-203L2.4		852	0.69
chr2_143894055_143894206	0.21	ARHGAP15	Rho GTPase activating protein 15	7247	0.27
chr6_6901128_6901378	0.21	ENSG00000240936	.	37877	0.21
chr1_172641897_172642048	0.21	FASLG	Fas ligand (TNF superfamily, member 6)	13814	0.25
chr19_40596900_40597601	0.21	ZNF780A	zinc finger protein 780A	405	0.58
chr4_164587444_164587843	0.21	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	52957	0.16
chr12_27020201_27020499	0.21	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	34219	0.16
chr5_50014096_50014414	0.21	PARP8	poly (ADP-ribose) polymerase family, member 8	50864	0.19
chr6_90805801_90805952	0.21	ENSG00000222078	.	94651	0.08
chr3_121555791_121555976	0.21	EAF2	ELL associated factor 2	1799	0.29
chr12_46616110_46616335	0.21	SLC38A1	solute carrier family 38, member 1	45262	0.19
chr4_139110592_139110791	0.21	ENSG00000250033	.	17907	0.26
chr9_74510793_74510957	0.21	ENSG00000200922	.	6591	0.2
chr2_159169362_159169513	0.20	CCDC148	coiled-coil domain containing 148	68035	0.12
chr2_109230721_109231015	0.20	LIMS1	LIM and senescent cell antigen-like domains 1	6854	0.25
chr2_163202650_163202937	0.20	GCA	grancalcin, EF-hand calcium binding protein	1945	0.4
chr8_84016227_84016378	0.20	NA	NA	> 10⁶	NA
chr21_27937735_27938086	0.20	CYYR1	cysteine/tyrosine-rich 1	7585	0.31
chr3_113472934_113473085	0.20	ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	7112	0.19
chr4_159463534_159463700	0.20	RXFP1	relaxin/insulin-like family peptide receptor 1	20488	0.2
chrX_133682110_133682299	0.20	ENSG00000223749	.	1463	0.24
chr4_174293358_174293974	0.20	SAP30	Sin3A-associated protein, 30kDa	1572	0.28
chr12_111587807_111587958	0.20	CUX2	cut-like homeobox 2	50632	0.15
chr18_29602122_29602278	0.20	RNF125	ring finger protein 125, E3 ubiquitin protein ligase	3865	0.2
chr7_48431262_48431591	0.20	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	63234	0.15
chr12_123838647_123838798	0.20	SBNO1	strawberry notch homolog 1 (Drosophila)	3734	0.17
chr1_150598433_150598584	0.20	ENSA	endosulfine alpha	3084	0.15
chr5_40690408_40690559	0.20	PTGER4	prostaglandin E receptor 4 (subtype EP4)	10883	0.2
chr12_25227874_25228025	0.20	LRMP	lymphoid-restricted membrane protein	14759	0.19
chr13_77951468_77951619	0.20	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	50364	0.17
chr9_82254771_82254922	0.20	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	12662	0.33
chr2_201239064_201239418	0.20	ENSG00000201649	.	1343	0.41
chr1_193407760_193407911	0.20	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	252051	0.02
chr4_11471978_11472173	0.20	HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	40686	0.19
chr8_126349663_126349814	0.20	RP11-550A5.2		13920	0.24
chr3_194381967_194382405	0.20	ENSG00000221718	.	5759	0.13
chr16_12897818_12897969	0.20	CPPED1	calcineurin-like phosphoesterase domain containing 1	19	0.98
chr2_48545707_48546468	0.20	FOXN2	forkhead box N2	4238	0.26
chr9_139684993_139685210	0.20	TMEM141	transmembrane protein 141	706	0.3
chr4_55529764_55530043	0.20	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	5818	0.34
chr6_135514882_135515033	0.20	MYB-AS1	MYB antisense RNA 1	2176	0.29
chr3_41260858_41261220	0.20	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	2538	0.45
chr20_40298054_40298205	0.20	ENSG00000252386	.	15601	0.19
chr6_150646274_150646425	0.20	ENSG00000201628	.	1550	0.48
chr13_48726665_48726872	0.20	MED4	mediator complex subunit 4	57501	0.12
chr4_11506945_11507096	0.20	HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	75631	0.11
chr3_98283780_98283931	0.20	CPOX	coproporphyrinogen oxidase	28712	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.3	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.2	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.2	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.2	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.2	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.2	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.3	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.9	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.4	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.4	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.3	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0042663	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0048263	determination of dorsal identity(GO:0048263)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.3	GO:0006983	ER overload response(GO:0006983)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.3	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:2000108	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.2	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0061054	dermatome development(GO:0061054)
0.0	0.1	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.2	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.2	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.3	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.5	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.0	GO:0032849	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.0	0.2	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:1903038	negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.2	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0033567	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.2	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0002524	hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0	0.3	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.3	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0060324	face development(GO:0060324)
0.0	0.1	GO:0098930	axonal transport(GO:0098930)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.0	GO:0060117	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088) auditory receptor cell development(GO:0060117)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.3	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.0	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0015669	gas transport(GO:0015669)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.3	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	1.1	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.1	GO:0070875	positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0032071	regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0001783	B cell apoptotic process(GO:0001783)
0.0	0.0	GO:0060479	lung cell differentiation(GO:0060479)
0.0	0.0	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0050702	interleukin-1 beta secretion(GO:0050702)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0018200	peptidyl-glutamic acid modification(GO:0018200)
0.0	0.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.4	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:1901998	antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.7	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.0	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.0	GO:0046637	regulation of alpha-beta T cell differentiation(GO:0046637)
0.0	0.0	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	0.0	GO:0043486	histone exchange(GO:0043486)
0.0	0.6	GO:0006413	translational initiation(GO:0006413)
0.0	0.0	GO:0006900	membrane budding(GO:0006900)
0.0	0.0	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.5	GO:0009247	glycolipid biosynthetic process(GO:0009247)
0.0	1.0	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.2	GO:0008380	RNA splicing(GO:0008380)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:0007140	male meiosis(GO:0007140)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.0	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.0	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.2	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.0	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.4	GO:0006968	cellular defense response(GO:0006968)
0.0	0.2	GO:0046949	fatty-acyl-CoA metabolic process(GO:0035337) fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.2	GO:0001709	cell fate determination(GO:0001709)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.0	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.2	GO:0045762	positive regulation of adenylate cyclase activity(GO:0045762)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	3.1	GO:0006397	mRNA processing(GO:0006397)
0.0	0.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.0	GO:0070228	regulation of lymphocyte apoptotic process(GO:0070228)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.1	GO:0050854	regulation of antigen receptor-mediated signaling pathway(GO:0050854)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.3	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0031045	dense core granule(GO:0031045)
0.0	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0043209	myelin sheath(GO:0043209)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.7	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.5	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	1.0	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.7	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0070938	contractile ring(GO:0070938)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.5	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.4	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.5	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.7	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.3	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.7	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0055037	recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	1.2	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0004370	glycerol kinase activity(GO:0004370)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.4	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.5	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0016531	metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.0	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.3	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.0	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	1.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.9	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.7	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.9	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.7	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID RAC1 PATHWAY	RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.0	REACTOME M G1 TRANSITION	Genes involved in M/G1 Transition
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	1.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.0	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.9	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway

Results for IRX5

Z-value: 0.85

Motif logo

Transcription factors associated with IRX5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IRX5 motif across conditions

Conditions sorted by the z-value of the IRX5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: