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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ISL1

Z-value: 4.21

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Transcription factors associated with ISL1

Gene Symbol	Gene ID	Gene Info
ISL1 Ensembl NCBI GeneCards UniProt	ENSG00000016082.10	ISL LIM homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_50694910_50695061	ISL1	15479	0.218292	-0.77	1.5e-02	Click!
chr5_50678612_50678763	ISL1	234	0.734623	-0.50	1.7e-01	Click!
chr5_50679370_50679533	ISL1	55	0.790741	-0.49	1.8e-01	Click!

Activity of the ISL1 motif across conditions

Conditions sorted by the z-value of the ISL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_226985191_226985665	2.66	ITPKB	inositol-trisphosphate 3-kinase B	58404	0.12
chr5_156621341_156621645	0.92	ITK	IL2-inducible T-cell kinase	13656	0.12
chr14_98642580_98643004	0.88	ENSG00000222066	.	155295	0.04
chr1_226985906_226986297	0.88	ITPKB	inositol-trisphosphate 3-kinase B	59077	0.12
chr3_46007058_46007478	0.87	FYCO1	FYVE and coiled-coil domain containing 1	7115	0.18
chr14_61871611_61871960	0.84	PRKCH	protein kinase C, eta	14373	0.24
chr5_61874985_61875174	0.83	LRRC70	leucine rich repeat containing 70	377	0.53
chr13_24839780_24840285	0.82	SPATA13	spermatogenesis associated 13	4794	0.19
chr10_11275555_11276261	0.82	RP3-323N1.2		62569	0.12
chr2_231527255_231527406	0.82	CAB39	calcium binding protein 39	50230	0.13
chrX_118782694_118782994	0.80	ENSG00000211578	.	2033	0.29
chr7_50459939_50460090	0.80	ENSG00000200815	.	43064	0.16
chr17_76800936_76801093	0.79	USP36	ubiquitin specific peptidase 36	5210	0.19
chr11_118762748_118763140	0.77	RP11-158I9.5		4493	0.11
chr3_107697281_107697722	0.76	CD47	CD47 molecule	79707	0.11
chr4_185383895_185384196	0.74	RP11-326I11.5		9718	0.19
chr11_48078680_48078903	0.74	ENSG00000263693	.	39543	0.14
chr13_100195644_100195875	0.72	ENSG00000212197	.	7109	0.19
chr11_104901971_104902200	0.72	CASP1	caspase 1, apoptosis-related cysteine peptidase	855	0.57
chr14_99399270_99399624	0.72	C14orf177	chromosome 14 open reading frame 177	221490	0.02
chr12_66701145_66701449	0.72	HELB	helicase (DNA) B	4972	0.19
chr1_169665494_169666108	0.71	SELL	selectin L	15038	0.19
chr2_85069477_85069628	0.71	TRABD2A	TraB domain containing 2A	38654	0.15
chr12_89715283_89715434	0.71	DUSP6	dual specificity phosphatase 6	29590	0.2
chr11_121328365_121328666	0.71	RP11-730K11.1		4793	0.26
chr10_31081414_31081648	0.70	RP11-330O11.3		40785	0.17
chr17_33379341_33379559	0.70	ENSG00000238858	.	2063	0.21
chr1_65342177_65342328	0.70	JAK1	Janus kinase 1	89935	0.08
chr10_112621844_112622553	0.69	PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	9367	0.15
chr2_113944482_113944729	0.69	PSD4	pleckstrin and Sec7 domain containing 4	9252	0.14
chr9_138981710_138981861	0.68	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	5346	0.22
chrX_44821643_44821794	0.67	ENSG00000252113	.	76967	0.1
chr15_93684168_93684384	0.67	RGMA	repulsive guidance molecule family member a	51843	0.15
chr1_76735415_76735707	0.66	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	195157	0.03
chr1_193380664_193380815	0.66	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	224955	0.02
chr12_22749964_22750115	0.66	RP11-268P4.4		27910	0.19
chr10_35420533_35420808	0.66	ENSG00000253054	.	3701	0.17
chr9_132657634_132657785	0.65	FNBP1	formin binding protein 1	23880	0.15
chr11_129725870_129726021	0.64	TMEM45B	transmembrane protein 45B	5718	0.26
chr14_61872843_61873172	0.64	PRKCH	protein kinase C, eta	15595	0.24
chr12_65095005_65095308	0.64	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	4827	0.17
chr4_109027301_109027793	0.64	LEF1	lymphoid enhancer-binding factor 1	59910	0.12
chr17_37929536_37929825	0.64	IKZF3	IKAROS family zinc finger 3 (Aiolos)	4798	0.15
chr14_68750936_68751124	0.63	ENSG00000243546	.	47774	0.17
chr2_89050765_89050916	0.63	ENSG00000221686	.	15995	0.13
chr7_43646363_43646514	0.63	STK17A	serine/threonine kinase 17a	23774	0.16
chr17_74184327_74184668	0.63	RNF157	ring finger protein 157	21334	0.12
chr14_98640158_98640463	0.63	ENSG00000222066	.	157777	0.04
chr2_143898363_143898928	0.63	ARHGAP15	Rho GTPase activating protein 15	11762	0.25
chr15_85316072_85316223	0.62	ZNF592	zinc finger protein 592	9738	0.14
chr6_37476511_37476688	0.62	CCDC167	coiled-coil domain containing 167	8901	0.21
chrX_135818033_135818184	0.62	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	31394	0.15
chr13_114943882_114944143	0.62	RASA3	RAS p21 protein activator 3	45926	0.12
chr22_20817368_20817809	0.62	ENSG00000255156	.	12010	0.09
chr5_79486493_79486756	0.62	ENSG00000239159	.	48784	0.12
chr16_79077458_79077675	0.62	RP11-556H2.4		34565	0.14
chr6_112063581_112063732	0.61	FYN	FYN oncogene related to SRC, FGR, YES	16661	0.25
chr2_136896515_136896760	0.61	CXCR4	chemokine (C-X-C motif) receptor 4	20902	0.26
chr9_92083779_92083991	0.61	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	10920	0.23
chr1_101394347_101394839	0.61	SLC30A7	solute carrier family 30 (zinc transporter), member 7	32783	0.12
chr2_37844931_37845082	0.61	AC006369.2		17727	0.22
chr10_28647893_28648044	0.61	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	24553	0.18
chr5_39156051_39156436	0.60	FYB	FYN binding protein	46886	0.15
chr9_77727295_77727446	0.60	OSTF1	osteoclast stimulating factor 1	23911	0.16
chr1_24810563_24810915	0.60	RCAN3	RCAN family member 3	18648	0.15
chr7_44668438_44669074	0.60	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	4695	0.22
chr1_209946191_209946467	0.60	TRAF3IP3	TRAF3 interacting protein 3	4369	0.16
chr6_143458609_143458760	0.60	AIG1	androgen-induced 1	11297	0.23
chr21_43841570_43841787	0.60	ENSG00000252619	.	3976	0.16
chr4_122112223_122112496	0.60	ENSG00000252183	.	1699	0.43
chr11_122926719_122927026	0.60	ENSG00000200879	.	1997	0.22
chr11_6759298_6759668	0.60	GVINP1	GTPase, very large interferon inducible pseudogene 1	16372	0.12
chr1_68152283_68152754	0.60	GADD45A	growth arrest and DNA-damage-inducible, alpha	1634	0.43
chr8_126937126_126937461	0.59	ENSG00000206695	.	24098	0.28
chr13_41217849_41218020	0.59	FOXO1	forkhead box O1	22800	0.22
chr2_198099388_198099568	0.58	ANKRD44	ankyrin repeat domain 44	36716	0.15
chr7_17158432_17158583	0.58	AC003075.4		162420	0.04
chr17_10606341_10606492	0.58	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	1801	0.25
chr12_90096202_90096439	0.58	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	6288	0.22
chr13_75897174_75897393	0.58	TBC1D4	TBC1 domain family, member 4	18384	0.24
chr6_42002666_42002817	0.58	CCND3	cyclin D3	13683	0.15
chr15_38869689_38869840	0.58	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	11988	0.2
chr12_123721975_123722320	0.58	C12orf65	chromosome 12 open reading frame 65	3845	0.15
chr11_10822660_10822811	0.58	EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	173	0.74
chr17_14307504_14307689	0.58	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	103196	0.08
chr2_136890291_136890609	0.58	CXCR4	chemokine (C-X-C motif) receptor 4	14715	0.27
chr11_104607373_104607580	0.57	CASP12	caspase 12 (gene/pseudogene)	161665	0.04
chrX_41591488_41591639	0.57	GPR82	G protein-coupled receptor 82	8155	0.22
chr2_197015443_197015626	0.57	RP11-347P5.1		453	0.83
chr17_35917117_35917268	0.57	SYNRG	synergin, gamma	14704	0.18
chr7_50436926_50437104	0.57	ENSG00000200815	.	66063	0.11
chr15_38778897_38779061	0.57	RP11-102L12.2		16075	0.17
chr1_169659354_169659683	0.57	SELL	selectin L	21321	0.18
chr1_156933706_156934136	0.57	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	15115	0.14
chr19_10252991_10253357	0.56	EIF3G	eukaryotic translation initiation factor 3, subunit G	22596	0.07
chr2_46578248_46578673	0.56	EPAS1	endothelial PAS domain protein 1	53919	0.14
chr1_198662133_198662301	0.56	RP11-553K8.5		26027	0.22
chr12_104296222_104296713	0.56	HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	27418	0.12
chr2_175767589_175767781	0.56	CHN1	chimerin 1	55206	0.12
chr13_52396732_52397247	0.56	RP11-327P2.5		18556	0.18
chr6_4031031_4031545	0.56	PRPF4B	pre-mRNA processing factor 4B	9361	0.15
chr9_127903519_127903783	0.56	SCAI	suppressor of cancer cell invasion	2124	0.33
chrX_13102668_13102885	0.56	FAM9C	family with sequence similarity 9, member C	39975	0.19
chr3_71519493_71519644	0.56	ENSG00000221264	.	71672	0.11
chr1_116931483_116931823	0.56	AL136376.1	Uncharacterized protein	4935	0.17
chr9_92109429_92109613	0.55	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	2826	0.29
chr18_9122102_9122337	0.55	RP11-143J12.3		6344	0.16
chr2_135005561_135006113	0.55	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	5993	0.26
chr2_38891670_38891832	0.55	GALM	galactose mutarotase (aldose 1-epimerase)	1301	0.42
chr3_113941978_113942129	0.55	RP11-553L6.2		8815	0.17
chr10_22028920_22029395	0.55	ENSG00000252634	.	45064	0.15
chr7_127750538_127750689	0.55	ENSG00000207588	.	28700	0.19
chr8_37132456_37132991	0.55	RP11-150O12.6		241816	0.02
chr20_32087161_32087382	0.55	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	9348	0.19
chr13_24836062_24836323	0.55	SPATA13-AS1	SPATA13 antisense RNA 1	7615	0.17
chr5_118524120_118524302	0.54	ENSG00000264536	.	33879	0.15
chr15_92470898_92471049	0.54	SLCO3A1	solute carrier organic anion transporter family, member 3A1	73622	0.12
chr12_32907815_32908305	0.54	YARS2	tyrosyl-tRNA synthetase 2, mitochondrial	776	0.72
chr7_8188847_8189208	0.54	ENSG00000265212	.	5625	0.24
chr7_17049389_17049589	0.54	AGR3	anterior gradient 3	127878	0.05
chr1_20015723_20015939	0.54	HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	24051	0.16
chr6_112034188_112034365	0.54	FYN	FYN oncogene related to SRC, FGR, YES	6989	0.26
chr12_90087131_90087371	0.54	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	15357	0.2
chr12_75887752_75887903	0.54	RP11-585P4.5		4227	0.21
chr5_67571504_67571837	0.54	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	4398	0.33
chr14_103249310_103249461	0.54	TRAF3	TNF receptor-associated factor 3	5430	0.2
chr15_44970403_44970608	0.53	PATL2	protein associated with topoisomerase II homolog 2 (yeast)	1419	0.34
chr2_202134110_202134598	0.53	CASP8	caspase 8, apoptosis-related cysteine peptidase	3007	0.26
chr15_60875764_60876131	0.53	RORA	RAR-related orphan receptor A	8793	0.23
chr3_43352509_43352660	0.53	ENSG00000241939	.	3859	0.22
chr9_92108756_92109116	0.53	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	3411	0.27
chr6_143254515_143254784	0.53	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	11689	0.26
chr12_106640527_106640982	0.53	RP11-651L5.2		20	0.96
chr1_111210147_111210423	0.53	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	7370	0.19
chr17_42574366_42574517	0.53	GPATCH8	G patch domain containing 8	6318	0.19
chr13_41145736_41145887	0.53	AL133318.1	Uncharacterized protein	34488	0.2
chrX_78394950_78395149	0.53	GPR174	G protein-coupled receptor 174	31420	0.25
chr1_65328772_65328923	0.53	RAVER2	ribonucleoprotein, PTB-binding 2	85100	0.09
chr17_1288425_1288576	0.52	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	14975	0.17
chr3_197578509_197578660	0.52	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	3712	0.21
chr6_35560926_35561186	0.52	ENSG00000212579	.	58539	0.09
chr19_15559479_15560330	0.52	ENSG00000269782	.	455	0.47
chr17_33694633_33695079	0.52	SLFN11	schlafen family member 11	5770	0.2
chr2_163168170_163168321	0.52	IFIH1	interferon induced with helicase C domain 1	6949	0.22
chr2_42523506_42523974	0.52	EML4	echinoderm microtubule associated protein like 4	4653	0.29
chr8_19307069_19307220	0.52	SH2D4A	SH2 domain containing 4A	130043	0.06
chr17_63032921_63033072	0.52	RP11-583F2.5		15031	0.17
chr6_35272489_35272748	0.52	DEF6	differentially expressed in FDCP 6 homolog (mouse)	4897	0.2
chr1_158899632_158899783	0.52	PYHIN1	pyrin and HIN domain family, member 1	879	0.64
chr2_85066895_85067327	0.51	TRABD2A	TraB domain containing 2A	41095	0.14
chr2_182146941_182147092	0.51	ENSG00000266705	.	23363	0.27
chr4_143483473_143483728	0.51	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	1778	0.54
chr16_77226560_77226711	0.51	MON1B	MON1 secretory trafficking family member B	1538	0.39
chr13_109063951_109064142	0.51	ENSG00000223177	.	110367	0.07
chr2_191925730_191925888	0.51	ENSG00000231858	.	39557	0.13
chr22_40513966_40514117	0.51	TNRC6B	trinucleotide repeat containing 6B	59888	0.12
chr20_47428573_47428748	0.51	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	15760	0.25
chr4_6153657_6153808	0.51	JAKMIP1	janus kinase and microtubule interacting protein 1	42612	0.19
chr3_52297144_52297508	0.51	ENSG00000199150	.	5053	0.1
chr12_45223053_45223246	0.50	NELL2	NEL-like 2 (chicken)	46102	0.17
chr7_130653209_130653360	0.50	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	15584	0.25
chr5_156341253_156341404	0.50	TIMD4	T-cell immunoglobulin and mucin domain containing 4	21359	0.23
chr8_81288726_81288959	0.50	ENSG00000252884	.	28909	0.19
chr5_177252019_177252317	0.50	FAM153A	family with sequence similarity 153, member A	41769	0.1
chr10_8128417_8128568	0.50	GATA3	GATA binding protein 3	31723	0.25
chr3_33099865_33100102	0.50	GLB1	galactosidase, beta 1	38301	0.13
chr9_115593446_115593597	0.50	SNX30	sorting nexin family member 30	7344	0.23
chr20_34318490_34318786	0.50	RBM39	RNA binding motif protein 39	1372	0.29
chr6_35566907_35567293	0.50	ENSG00000212579	.	52495	0.1
chr14_99171229_99171380	0.50	C14orf177	chromosome 14 open reading frame 177	6646	0.34
chr3_33065058_33065320	0.50	CCR4	chemokine (C-C motif) receptor 4	72123	0.08
chr9_134546803_134547477	0.50	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	38089	0.16
chr4_90168124_90168275	0.50	GPRIN3	GPRIN family member 3	4146	0.34
chr2_68980217_68980369	0.50	ARHGAP25	Rho GTPase activating protein 25	18279	0.23
chr11_17308371_17308522	0.50	NUCB2	nucleobindin 2	8425	0.21
chr14_66344802_66344953	0.50	CTD-2014B16.3	Uncharacterized protein	126364	0.06
chr17_65721611_65721857	0.50	NOL11	nucleolar protein 11	4168	0.23
chrX_123527996_123528147	0.50	SH2D1A	SH2 domain containing 1A	47632	0.19
chr1_167472608_167472887	0.49	CD247	CD247 molecule	15028	0.19
chr5_156681128_156681568	0.49	CYFIP2	cytoplasmic FMR1 interacting protein 2	11743	0.13
chr16_16053619_16053929	0.49	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	10340	0.22
chr3_18786984_18787213	0.49	ENSG00000228956	.	138	0.98
chr12_92525505_92525749	0.49	C12orf79	chromosome 12 open reading frame 79	5170	0.2
chr16_11830483_11830634	0.49	TXNDC11	thioredoxin domain containing 11	572	0.7
chr2_64011466_64011617	0.49	UGP2	UDP-glucose pyrophosphorylase 2	56533	0.14
chr12_113523386_113523537	0.49	DTX1	deltex homolog 1 (Drosophila)	27966	0.13
chr8_144938889_144939447	0.49	ENSG00000264144	.	12928	0.09
chr7_150207555_150208051	0.49	GIMAP7	GTPase, IMAP family member 7	4115	0.23
chr21_44154403_44154727	0.49	AP001627.1		7303	0.24
chr2_143932459_143932876	0.49	RP11-190J23.1		2926	0.36
chr15_40475512_40475663	0.49	BUB1B	BUB1 mitotic checkpoint serine/threonine kinase B	22319	0.12
chr10_92962405_92962639	0.49	PCGF5	polycomb group ring finger 5	17386	0.29
chr7_91762849_91763175	0.48	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	832	0.4
chr10_124175590_124175841	0.48	ENSG00000265442	.	766	0.63
chr20_32212304_32212518	0.48	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	14134	0.12
chr18_21620931_21621172	0.48	TTC39C	tetratricopeptide repeat domain 39C	24453	0.14
chr8_125338873_125339084	0.48	TMEM65	transmembrane protein 65	45955	0.15
chr14_61971409_61971560	0.48	RP11-47I22.4		24362	0.18
chrX_19761943_19762207	0.48	SH3KBP1	SH3-domain kinase binding protein 1	2454	0.43
chr17_65516191_65516342	0.48	CTD-2653B5.1		4331	0.22

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.6	2.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.5	1.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.5	1.6	GO:0010459	negative regulation of heart rate(GO:0010459)
0.5	1.8	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.4	0.4	GO:0002326	B cell lineage commitment(GO:0002326)
0.4	1.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.4	1.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4	1.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.4	1.5	GO:0002517	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.3	1.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.3	1.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.3	1.4	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3	1.0	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.3	1.5	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.3	0.9	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.3	0.8	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.3	0.8	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3	0.5	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.3	1.9	GO:0007172	signal complex assembly(GO:0007172)
0.3	0.8	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.3	1.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.3	0.8	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.3	1.8	GO:0006198	cAMP catabolic process(GO:0006198)
0.3	0.8	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.2	1.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.2	1.2	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2	0.5	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.5	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.2	0.5	GO:0030223	neutrophil differentiation(GO:0030223)
0.2	0.7	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	1.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.2	0.5	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.2	0.2	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.2	1.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2	1.7	GO:0002839	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.2	0.8	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2	0.4	GO:0097709	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.2	1.7	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.2	0.8	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.2	14.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.2	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.2	1.6	GO:0006491	N-glycan processing(GO:0006491)
0.2	0.4	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.2	1.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	1.9	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.2	0.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	0.6	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.2	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.2	0.5	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2	1.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.2	0.5	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.5	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	0.2	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.2	0.2	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.2	0.5	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.2	0.5	GO:0002507	tolerance induction(GO:0002507)
0.2	0.8	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2	0.5	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.2	0.6	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2	0.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.2	1.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.2	0.5	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.9	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.4	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	1.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.4	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.4	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.4	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.1	0.9	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.1	0.3	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.4	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	0.7	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.7	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.4	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.5	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.4	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	1.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.4	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.4	GO:0015801	aromatic amino acid transport(GO:0015801)
0.1	0.4	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.3	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	0.4	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.3	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.4	GO:0045056	transcytosis(GO:0045056)
0.1	0.2	GO:0034776	response to histamine(GO:0034776)
0.1	0.4	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	0.4	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.4	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	0.4	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	1.5	GO:0000303	response to superoxide(GO:0000303)
0.1	0.2	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.4	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.4	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.2	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.4	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.6	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.8	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.3	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.1	0.3	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.4	GO:0031033	myosin filament organization(GO:0031033)
0.1	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.3	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1	1.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.4	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.1	0.5	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.3	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.7	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.1	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.7	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.1	0.2	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1	0.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1	0.3	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.3	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.4	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.8	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	1.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.1	0.4	GO:0033080	immature T cell proliferation in thymus(GO:0033080)
0.1	1.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.4	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1	0.4	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.1	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.4	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	0.4	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	1.4	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.8	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.7	GO:0036314	response to sterol(GO:0036314) response to cholesterol(GO:0070723)
0.1	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	1.6	GO:0006611	protein export from nucleus(GO:0006611)
0.1	0.4	GO:1902750	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.1	0.4	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.5	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	1.2	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.8	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.1	0.4	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1	0.4	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.1	0.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	2.8	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1	0.9	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.3	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	1.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	1.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.7	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.2	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.7	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.2	GO:0002823	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.4	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.1	0.2	GO:0031529	ruffle organization(GO:0031529)
0.1	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.2	GO:2000649	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1	0.9	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.4	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.6	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.1	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.8	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.8	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.2	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1	1.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.2	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1	2.0	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.1	0.2	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.3	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.1	0.1	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.1	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.2	GO:0050955	thermoception(GO:0050955)
0.1	0.1	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.1	0.3	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.1	2.1	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.1	0.1	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.4	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.3	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1	0.5	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.2	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.1	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.1	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.3	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.5	GO:0015074	DNA integration(GO:0015074)
0.1	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.8	GO:0045730	respiratory burst(GO:0045730)
0.1	0.4	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.1	1.6	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.1	0.3	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.1	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.1	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.2	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1	0.1	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.1	0.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1	0.2	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.1	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.1	GO:0010613	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.1	0.1	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.1	0.2	GO:0006545	glycine biosynthetic process(GO:0006545)
0.1	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	0.4	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.4	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.1	GO:0032060	bleb assembly(GO:0032060)
0.1	0.4	GO:0032119	sequestering of zinc ion(GO:0032119)
0.1	0.2	GO:0031442	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1	0.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.1	1.1	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.1	0.3	GO:0045116	protein neddylation(GO:0045116)
0.1	0.4	GO:0000266	mitochondrial fission(GO:0000266)
0.1	0.3	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.1	0.4	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1	0.3	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	0.2	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.1	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.1	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.1	GO:0016556	mRNA modification(GO:0016556)
0.1	0.2	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.1	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	0.3	GO:0006012	galactose metabolic process(GO:0006012)
0.1	0.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.1	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.1	0.8	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.4	GO:2000134	negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1	0.1	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.4	GO:0031648	protein destabilization(GO:0031648)
0.1	0.3	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.1	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1	3.6	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1	0.1	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.1	0.2	GO:0042117	monocyte activation(GO:0042117)
0.1	0.1	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1	0.1	GO:0010535	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.1	0.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	0.3	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.2	GO:0006999	nuclear pore organization(GO:0006999)
0.1	0.2	GO:0009301	snRNA transcription(GO:0009301)
0.1	0.3	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.1	0.9	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	0.3	GO:0002456	T cell mediated immunity(GO:0002456)
0.1	1.0	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.1	0.2	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.5	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.2	GO:0045414	regulation of interleukin-8 biosynthetic process(GO:0045414)
0.1	2.8	GO:0008360	regulation of cell shape(GO:0008360)
0.1	0.1	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.1	0.1	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	1.2	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.5	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974) negative regulation of DNA biosynthetic process(GO:2000279)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.4	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.2	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.7	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.2	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0042482	positive regulation of odontogenesis(GO:0042482)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.0	GO:0019614	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) dopamine catabolic process(GO:0042420) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.7	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.2	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.6	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.2	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.2	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.7	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.5	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.1	GO:0019048	modulation by virus of host morphology or physiology(GO:0019048)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.2	GO:0038061	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.2	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.4	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.2	GO:0042891	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.3	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.5	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.3	GO:0001510	RNA methylation(GO:0001510)
0.0	0.7	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.3	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.2	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.9	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.4	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	1.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.2	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.9	GO:0021549	cerebellum development(GO:0021549)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.3	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.8	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	7.9	GO:0006397	mRNA processing(GO:0006397)
0.0	0.3	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.7	GO:0007031	peroxisome organization(GO:0007031)
0.0	1.7	GO:0006405	RNA export from nucleus(GO:0006405)
0.0	0.8	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	1.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	1.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.1	GO:0098930	axonal transport(GO:0098930)
0.0	0.5	GO:0071554	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.2	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.3	GO:0007140	male meiosis(GO:0007140)
0.0	0.0	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	1.5	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.1	GO:0014002	astrocyte development(GO:0014002)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.4	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.4	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.3	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.3	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.1	GO:1903513	endoplasmic reticulum to cytosol transport(GO:1903513)
0.0	1.5	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.7	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0014010	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	0.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.3	GO:0016073	snRNA metabolic process(GO:0016073)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0032682	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.4	GO:0008380	RNA splicing(GO:0008380)
0.0	0.1	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.3	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.1	GO:0031123	RNA 3'-end processing(GO:0031123)
0.0	0.2	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.0	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.4	GO:0009303	rRNA transcription(GO:0009303) ncRNA transcription(GO:0098781)
0.0	0.1	GO:0030888	regulation of B cell proliferation(GO:0030888) positive regulation of B cell proliferation(GO:0030890)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.0	GO:1903514	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0006301	postreplication repair(GO:0006301)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709) positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.1	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:1904375	regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0	0.0	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0046477	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0	0.4	GO:0051017	actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.3	GO:0046849	bone remodeling(GO:0046849)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.0	GO:0046951	acetoacetic acid biosynthetic process(GO:0043441) ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.0	GO:0072162	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0030812	UDP-glucose metabolic process(GO:0006011) negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.0	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.2	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.1	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.0	GO:0010738	regulation of protein kinase A signaling(GO:0010738) positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.0	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.5	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0002016	regulation of blood volume by renin-angiotensin(GO:0002016)
0.0	0.2	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0090174	organelle membrane fusion(GO:0090174)
0.0	0.1	GO:0003417	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.4	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.3	GO:0007030	Golgi organization(GO:0007030)
0.0	0.8	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.2	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.4	GO:0048477	oogenesis(GO:0048477)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.7	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.0	GO:0006266	DNA ligation(GO:0006266)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.0	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.3	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0006400	tRNA modification(GO:0006400)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.1	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.2	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0010165	response to X-ray(GO:0010165)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	1.2	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.1	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.0	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0051956	negative regulation of organic acid transport(GO:0032891) negative regulation of amino acid transport(GO:0051956)
0.0	0.1	GO:0030032	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.1	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0010828	positive regulation of glucose transport(GO:0010828)
0.0	0.0	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.1	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.0	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.0	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.0	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.0	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.0	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.0	0.5	GO:0007269	neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0	0.0	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.0	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.0	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.4	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0	0.2	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.0	GO:1903319	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.0	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	1.4	GO:0006396	RNA processing(GO:0006396)
0.0	0.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0006997	nucleus organization(GO:0006997)
0.0	0.0	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.0	0.4	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	0.0	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0090109	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of cell junction assembly(GO:1901888) regulation of adherens junction organization(GO:1903391)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3	0.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	0.8	GO:0072487	MSL complex(GO:0072487)
0.2	0.7	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2	1.9	GO:0001891	phagocytic cup(GO:0001891)
0.2	0.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.8	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	2.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	2.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	0.7	GO:0005827	polar microtubule(GO:0005827)
0.2	0.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.2	0.8	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	1.5	GO:0042101	T cell receptor complex(GO:0042101)
0.2	0.9	GO:0031264	death-inducing signaling complex(GO:0031264)
0.2	0.5	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	0.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	1.6	GO:0001772	immunological synapse(GO:0001772)
0.1	1.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.6	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.1	1.4	GO:0045120	pronucleus(GO:0045120)
0.1	0.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	1.0	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.6	GO:0070695	FHF complex(GO:0070695)
0.1	1.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.4	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.7	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1	0.4	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.7	GO:0042382	paraspeckles(GO:0042382)
0.1	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	1.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1	0.1	GO:0070552	BRISC complex(GO:0070552)
0.1	0.4	GO:0030891	VCB complex(GO:0030891)
0.1	0.3	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.9	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	1.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.4	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.2	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	3.1	GO:0030175	filopodium(GO:0030175)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	1.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	0.3	GO:0032009	early phagosome(GO:0032009)
0.1	0.3	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.2	GO:0030880	RNA polymerase complex(GO:0030880)
0.1	0.2	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.5	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.1	0.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.5	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.3	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	2.3	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.1	0.4	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	1.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.8	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.7	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.4	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.2	GO:0000800	lateral element(GO:0000800)
0.1	0.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.7	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.4	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:0001652	granular component(GO:0001652)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.1	GO:0000125	PCAF complex(GO:0000125)
0.1	0.3	GO:0016589	NURF complex(GO:0016589)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.6	GO:1904949	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.4	GO:0005883	neurofilament(GO:0005883)
0.1	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.1	0.7	GO:0071203	WASH complex(GO:0071203)
0.1	0.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.1	GO:0044454	nuclear chromosome part(GO:0044454)
0.1	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.1	0.4	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.2	GO:0042825	TAP complex(GO:0042825)
0.1	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	1.0	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	0.2	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	0.7	GO:0030914	STAGA complex(GO:0030914)
0.1	0.9	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.2	GO:0030904	retromer complex(GO:0030904)
0.1	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.2	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.1	0.8	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.4	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.0	GO:0042555	MCM complex(GO:0042555)
0.0	4.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.4	GO:0008278	cohesin complex(GO:0008278)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	1.0	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	0.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	1.6	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.3	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.7	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.5	GO:0032039	integrator complex(GO:0032039)
0.0	0.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.8	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.5	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.7	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	2.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	1.3	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.7	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	2.4	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.6	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	1.8	GO:0016607	nuclear speck(GO:0016607)
0.0	0.9	GO:0034708	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.6	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	1.3	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.6	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.3	GO:0005643	nuclear pore(GO:0005643)
0.0	0.4	GO:1902493	histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0	2.3	GO:0005769	early endosome(GO:0005769)
0.0	0.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	2.7	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	1.7	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	2.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.0	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.0	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	1.1	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	3.4	GO:0005768	endosome(GO:0005768)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.4	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	8.3	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.2	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.6	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	1.5	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.4	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	8.0	GO:0005730	nucleolus(GO:0005730)
0.0	0.1	GO:0032982	myosin filament(GO:0032982)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	5.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.2	GO:0005921	gap junction(GO:0005921)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4	1.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.4	2.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.3	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	1.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.3	1.7	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3	1.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.3	1.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.3	3.8	GO:0004697	protein kinase C activity(GO:0004697)
0.3	1.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3	1.1	GO:0015925	galactosidase activity(GO:0015925)
0.3	0.8	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3	0.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	0.8	GO:0042608	T cell receptor binding(GO:0042608)
0.3	2.0	GO:0005522	profilin binding(GO:0005522)
0.2	0.7	GO:0033691	sialic acid binding(GO:0033691)
0.2	0.7	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.2	0.5	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	2.0	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.2	1.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	0.7	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.2	0.7	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	0.6	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.2	1.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	2.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	1.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.2	0.5	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.2	0.9	GO:0005131	growth hormone receptor binding(GO:0005131)
0.2	1.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	1.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.2	2.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.2	0.6	GO:0016004	phospholipase activator activity(GO:0016004)
0.2	0.3	GO:0060229	lipase activator activity(GO:0060229)
0.1	0.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.1	GO:0030332	cyclin binding(GO:0030332)
0.1	1.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.8	GO:0050733	RS domain binding(GO:0050733)
0.1	3.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	2.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	1.0	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.6	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.2	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.8	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	2.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.6	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.3	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.6	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	1.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.9	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.5	GO:0031013	troponin I binding(GO:0031013)
0.1	2.0	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.7	GO:0004568	chitinase activity(GO:0004568)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.4	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.4	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.3	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.5	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	1.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.1	GO:0035197	siRNA binding(GO:0035197)
0.1	0.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	1.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	4.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.6	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.6	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	2.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.6	GO:0031701	angiotensin receptor binding(GO:0031701)
0.1	0.6	GO:0008494	translation activator activity(GO:0008494)
0.1	0.1	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.1	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	2.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	1.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.3	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.5	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	0.7	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.4	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.1	0.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	1.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.7	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	2.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	0.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.1	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.7	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.4	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.1	0.2	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.5	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	1.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.1	0.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.6	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	4.3	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	0.3	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	1.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.4	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.3	GO:0043495	protein anchor(GO:0043495)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	1.0	GO:0043022	ribosome binding(GO:0043022)
0.1	3.3	GO:0008301	DNA binding, bending(GO:0008301)
0.1	0.1	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.1	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.4	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.6	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.6	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.1	0.1	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	1.2	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.2	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.4	GO:0030507	spectrin binding(GO:0030507)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.2	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.1	0.2	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	0.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.8	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	0.9	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1	0.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.1	0.3	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.5	GO:0030276	clathrin binding(GO:0030276)
0.1	1.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	1.2	GO:0003823	antigen binding(GO:0003823)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.3	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.2	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	1.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.4	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.4	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.3	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.4	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	1.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.9	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.3	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.8	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.2	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	1.1	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	1.4	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.5	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	1.0	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	3.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	1.1	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.3	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	1.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.4	GO:0010181	FMN binding(GO:0010181)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	3.3	GO:0004386	helicase activity(GO:0004386)
0.0	0.4	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.3	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	1.5	GO:0005496	steroid binding(GO:0005496)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.6	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	2.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.7	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.4	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	1.7	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.0	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	6.1	GO:0005525	GTP binding(GO:0005525)
0.0	0.5	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	9.6	GO:0003723	RNA binding(GO:0003723)
0.0	0.3	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0080030	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	2.2	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019) lipoteichoic acid binding(GO:0070891)
0.0	0.0	GO:0004953	icosanoid receptor activity(GO:0004953)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.4	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.0	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	1.3	GO:0005179	hormone activity(GO:0005179)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0032561	guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.0	0.0	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0019829	cation-transporting ATPase activity(GO:0019829)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136) NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.0	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	16.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	3.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	4.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	2.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	1.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	1.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	0.8	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	4.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	1.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	6.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	3.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	3.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	3.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	1.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	1.6	PID BCR 5PATHWAY	BCR signaling pathway
0.1	0.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	1.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	1.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	0.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	1.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	0.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	1.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	2.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	0.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	1.1	PID MYC PATHWAY	C-MYC pathway
0.1	0.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	2.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	2.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.8	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	0.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.4	PID RHOA PATHWAY	RhoA signaling pathway
0.1	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	1.7	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.9	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.6	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.4	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.5	5.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.4	1.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.4	4.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.3	4.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	0.9	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.2	2.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	1.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	3.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	1.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.2	4.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.2	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	4.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	2.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.3	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.1	3.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	0.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	2.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	1.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	5.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	0.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	1.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.1	0.8	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	2.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	1.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.9	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.7	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	1.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	2.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	0.8	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	1.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.9	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.6	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	4.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	2.9	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	1.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.9	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.8	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	3.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.9	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.2	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.0	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.1	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade

Results for ISL1

Z-value: 4.21

Motif logo

Transcription factors associated with ISL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ISL1 motif across conditions

Conditions sorted by the z-value of the ISL1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: