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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for KLF12

Z-value: 1.53

Motif logo

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.12 KLF12

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
KLF12chr13_74655507_74655658528120.183538-0.956.9e-05Click!
KLF12chr13_74655680_74655831526390.184049-0.932.6e-04Click!
KLF12chr13_74332901_743330522362100.020378-0.891.3e-03Click!
KLF12chr13_74610738_74610889416270.221304-0.891.3e-03Click!
KLF12chr13_74610274_74610425411630.222906-0.872.0e-03Click!

Activity of the KLF12 motif across conditions

Conditions sorted by the z-value of the KLF12 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_101741938_101742937 0.56 CHSY1
 chondroitin sulfate synthase 1
 49700
 0.12
chr1_235053615_235054079 0.52 ENSG00000239690
 .
 13914
 0.26
chr3_197829897_197830311 0.52 AC073135.3
6973
 0.18
chr16_27253790_27254558 0.48 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 9775
 0.17
chr10_81006599_81006910 0.47 ZMIZ1
 zinc finger, MIZ-type containing 1
 59221
 0.14
chr7_75592437_75593112 0.37 POR
 P450 (cytochrome) oxidoreductase
 4387
 0.19
chr18_43588789_43589171 0.37 ENSG00000222179
 .
 19069
 0.17
chr3_148425752_148425954 0.35 AGTR1
 angiotensin II receptor, type 1
 10148
 0.28
chr9_116376964_116377197 0.34 RGS3
 regulator of G-protein signaling 3
 21314
 0.2
chr2_112133274_112133686 0.33 ENSG00000266139
 .
 54812
 0.17
chr15_67055010_67055873 0.30 SMAD6
 SMAD family member 6
 51406
 0.15
chr16_85110269_85110512 0.29 KIAA0513
 KIAA0513
 676
 0.74
chr10_80009477_80009629 0.29 ENSG00000201393
 .
 117711
 0.06
chr19_19083853_19084052 0.29 ENSG00000241172
 .
 14885
 0.1
chr12_57621019_57621403 0.29 ENSG00000202067
 .
 546
 0.57
chr11_131697224_131697416 0.27 AP004372.1
69682
 0.12
chr7_47267280_47267469 0.27 TNS3
 tensin 3
 52542
 0.19
chr15_75418307_75418680 0.27 ENSG00000252722
 .
 4486
 0.2
chr1_31870163_31870721 0.27 SERINC2
 serine incorporator 2
 11970
 0.15
chr15_100051927_100052783 0.27 AC015660.1
 HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
 13777
 0.21
chr7_31039847_31040026 0.26 GHRHR
 growth hormone releasing hormone receptor
 30788
 0.19
chr9_139963617_139963929 0.26 SAPCD2
 suppressor APC domain containing 2
 1267
 0.17
chr1_201642000_201642151 0.25 RP11-25B7.1
1197
 0.41
chr3_123140534_123140685 0.25 ADCY5
 adenylate cyclase 5
 1488
 0.52
chr13_98066168_98066319 0.25 RAP2A
 RAP2A, member of RAS oncogene family
 20233
 0.22
chr18_11149717_11149948 0.25 PIEZO2
 piezo-type mechanosensitive ion channel component 2
 1245
 0.64
chr4_8284667_8284834 0.25 HTRA3
 HtrA serine peptidase 3
 13246
 0.22
chr6_138752975_138753135 0.25 ENSG00000266555
 .
 3376
 0.26
chr7_116774717_116775343 0.25 ST7-AS2
 ST7 antisense RNA 2
 10582
 0.23
chrX_138285001_138285220 0.24 FGF13
 fibroblast growth factor 13
 577
 0.86
chr12_13132371_13132545 0.24 RP11-392P7.6
313
 0.84
chr10_35853810_35854235 0.24 GJD4
 gap junction protein, delta 4, 40.1kDa
 40316
 0.15
chr10_134389363_134389791 0.24 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 31853
 0.19
chr6_108786068_108786353 0.24 ENSG00000200799
 .
 72933
 0.1
chr11_70261497_70261648 0.24 CTTN
 cortactin
 4659
 0.16
chr19_50284218_50285014 0.24 AP2A1
 adaptor-related protein complex 2, alpha 1 subunit
 14225
 0.07
chr14_24837858_24838637 0.24 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 41
 0.94
chr10_44475712_44476330 0.24 ENSG00000238957
 .
 53967
 0.17
chr14_59213631_59214204 0.23 ENSG00000221427
 .
 24047
 0.25
chr18_74175634_74175889 0.23 ZNF516
 zinc finger protein 516
 26974
 0.16
chr17_77806355_77806637 0.23 CBX4
 chromobox homolog 4
 5184
 0.16
chr2_55364453_55364798 0.23 RTN4
 reticulon 4
 24868
 0.16
chrX_135241873_135242024 0.23 FHL1
 four and a half LIM domains 1
 7215
 0.22
chr9_93536564_93536934 0.22 SYK
 spleen tyrosine kinase
 27320
 0.27
chr11_61484218_61484613 0.22 MYRF
 myelin regulatory factor
 35706
 0.11
chr5_134691363_134691514 0.22 C5orf66
 chromosome 5 open reading frame 66
 17809
 0.18
chr17_79396387_79396545 0.22 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 8930
 0.11
chr17_32574614_32574944 0.22 CCL2
 chemokine (C-C motif) ligand 2
 7525
 0.13
chr1_150244620_150245106 0.22 C1orf54
 chromosome 1 open reading frame 54
 239
 0.83
chr2_223656927_223657285 0.22 ACSL3
 acyl-CoA synthetase long-chain family member 3
 68546
 0.11
chr6_158735535_158735730 0.22 TULP4
 tubby like protein 4
 1940
 0.42
chr15_64278058_64278452 0.22 DAPK2
 death-associated protein kinase 2
 54211
 0.11
chr17_25866922_25867277 0.22 KSR1
 kinase suppressor of ras 1
 42848
 0.14
chr22_44423046_44423480 0.22 PARVB
 parvin, beta
 3106
 0.31
chr5_139035453_139035988 0.22 CXXC5
 CXXC finger protein 5
 3420
 0.27
chr16_88220538_88220993 0.22 BANP
 BTG3 associated nuclear protein
 217141
 0.02
chr11_36112461_36112922 0.22 ENSG00000263389
 .
 81043
 0.09
chr20_60819766_60820011 0.21 OSBPL2
 oxysterol binding protein-like 2
 6308
 0.16
chr10_60336642_60336940 0.21 BICC1
 bicaudal C homolog 1 (Drosophila)
 63891
 0.15
chr19_1513130_1513873 0.21 ADAMTSL5
 ADAMTS-like 5
 313
 0.73
chr15_89565634_89565983 0.21 ENSG00000265866
 .
 50125
 0.12
chr2_85940079_85940420 0.21 ENSG00000199687
 .
 15211
 0.13
chr15_66909608_66909886 0.21 RP11-321F6.1
 HCG2003567; Uncharacterized protein
 35219
 0.12
chr11_111385155_111385345 0.21 C11orf88
 chromosome 11 open reading frame 88
 260
 0.77
chr22_46518789_46519087 0.21 ENSG00000207875
 .
 9372
 0.11
chr1_246345460_246345709 0.21 ENSG00000202184
 .
 6836
 0.23
chr20_3745410_3745658 0.21 C20orf27
 chromosome 20 open reading frame 27
 2841
 0.17
chr8_72087638_72087789 0.21 RP11-326E22.1
19956
 0.28
chr17_78746879_78747269 0.21 RP11-28G8.1
32358
 0.19
chr13_40468804_40469100 0.21 ENSG00000212553
 .
 37588
 0.21
chr15_101678714_101678865 0.21 RP11-505E24.2
52518
 0.13
chr6_170089803_170089954 0.21 ENSG00000265654
 .
 7466
 0.13
chr22_38438083_38438604 0.21 RP5-1039K5.16
8108
 0.11
chr1_110165621_110165808 0.21 AMPD2
 adenosine monophosphate deaminase 2
 722
 0.46
chr4_14531121_14531355 0.21 ENSG00000202449
 .
 161096
 0.04
chr19_17790699_17790876 0.21 UNC13A
 unc-13 homolog A (C. elegans)
 3809
 0.18
chr12_12016346_12017014 0.21 ETV6
 ets variant 6
 22191
 0.26
chr20_56482827_56482978 0.21 ENSG00000221007
 .
 11038
 0.21
chr15_101656629_101657100 0.21 RP11-505E24.2
30593
 0.19
chr14_65813869_65814020 0.21 ENSG00000266740
 .
 12043
 0.25
chr11_73032066_73032515 0.21 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 9680
 0.14
chr11_33982202_33982416 0.21 LMO2
 LIM domain only 2 (rhombotin-like 1)
 68473
 0.1
chr12_58846810_58846966 0.20 RP11-362K2.2
 Protein LOC100506869
 91019
 0.1
chr9_35553068_35553219 0.20 FAM166B
 family with sequence similarity 166, member B
 10753
 0.12
chr19_50310955_50311176 0.20 FUZ
 fuzzy planar cell polarity protein
 831
 0.3
chr19_17221488_17221977 0.20 MYO9B
 myosin IXB
 9204
 0.12
chr10_100108984_100109336 0.20 ENSG00000221419
 .
 45904
 0.13
chr1_149377811_149378198 0.20 FCGR1C
 Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
 8647
 0.14
chr16_85084815_85085194 0.20 KIAA0513
 KIAA0513
 11814
 0.21
chr12_125253324_125253475 0.20 SCARB1
 scavenger receptor class B, member 1
 48854
 0.17
chr2_206595324_206595734 0.20 AC007362.3
33148
 0.2
chr8_6149074_6149420 0.20 RP11-115C21.2
114816
 0.06
chr3_128690038_128690295 0.20 RP11-723O4.6
 Uncharacterized protein FLJ43738
 7
 0.97
chr7_73634593_73634808 0.20 LAT2
 linker for activation of T cells family, member 2
 10347
 0.15
chr22_38135230_38135506 0.20 TRIOBP
 TRIO and F-actin binding protein
 6867
 0.12
chr10_126916868_126917019 0.20 CTBP2
 C-terminal binding protein 2
 67313
 0.13
chr19_42470438_42470824 0.19 RABAC1
 Rab acceptor 1 (prenylated)
 7089
 0.14
chr19_39156030_39156719 0.19 ACTN4
 actinin, alpha 4
 17996
 0.11
chr4_3495752_3496051 0.19 RP11-529E10.6
10283
 0.16
chr10_104436480_104437015 0.19 TRIM8
 tripartite motif containing 8
 32103
 0.12
chr10_60338881_60339032 0.19 BICC1
 bicaudal C homolog 1 (Drosophila)
 66056
 0.14
chr15_40389876_40390209 0.19 BMF
 Bcl2 modifying factor
 8245
 0.15
chr22_39865304_39865652 0.19 MGAT3
 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
 3315
 0.18
chr16_81868234_81868705 0.19 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 48405
 0.17
chr10_73358221_73358464 0.19 CDH23
 cadherin-related 23
 27790
 0.22
chr8_144479919_144480248 0.19 RP11-909N17.2
14836
 0.09
chr16_31138954_31139105 0.19 KAT8
 K(lysine) acetyltransferase 8
 436
 0.58
chr6_611191_611411 0.19 HUS1B
 HUS1 checkpoint homolog b (S. pombe)
 45662
 0.17
chr11_69171319_69171574 0.19 MYEOV
 myeloma overexpressed
 109821
 0.07
chr3_10396103_10396350 0.19 ENSG00000264534
 .
 24313
 0.12
chr10_89790579_89790730 0.19 ENSG00000200891
 .
 36202
 0.2
chr3_69813958_69814283 0.19 MITF
 microphthalmia-associated transcription factor
 1158
 0.56
chr2_218776748_218776899 0.19 TNS1
 tensin 1
 6639
 0.26
chr15_89680763_89681294 0.19 ENSG00000239151
 .
 17018
 0.17
chr10_440686_440837 0.18 DIP2C
 DIP2 disco-interacting protein 2 homolog C (Drosophila)
 7012
 0.21
chr17_6269742_6269893 0.18 AIPL1
 aryl hydrocarbon receptor interacting protein-like 1
 68582
 0.1
chr16_89622328_89622613 0.18 SPG7
 spastic paraplegia 7 (pure and complicated autosomal recessive)
 2998
 0.14
chr18_10059619_10060204 0.18 ENSG00000263630
 .
 54717
 0.15
chr9_137216593_137216789 0.18 RXRA
 retinoid X receptor, alpha
 1735
 0.46
chr3_45687605_45688015 0.18 LIMD1-AS1
 LIMD1 antisense RNA 1
 42564
 0.12
chr11_73041779_73041997 0.18 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
 19278
 0.12
chr3_151122388_151122772 0.18 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
 19980
 0.18
chr3_122803672_122804475 0.18 PDIA5
 protein disulfide isomerase family A, member 5
 17878
 0.23
chr8_37660288_37660608 0.18 GPR124
 G protein-coupled receptor 124
 5674
 0.16
chr3_129666488_129666817 0.18 RP11-93K22.6
21485
 0.15
chr16_16168105_16168644 0.18 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 64661
 0.11
chr8_135033119_135033449 0.18 ENSG00000212273
 .
 376316
 0.01
chr10_115753755_115753984 0.18 ADRB1
 adrenoceptor beta 1
 49937
 0.13
chr2_27301986_27302370 0.18 EMILIN1
 elastin microfibril interfacer 1
 743
 0.39
chr9_38038631_38039019 0.18 SHB
 Src homology 2 domain containing adaptor protein B
 30383
 0.2
chr10_29297172_29297323 0.18 ENSG00000199402
 .
 133811
 0.05
chr15_82307610_82307761 0.18 ENSG00000222521
 .
 28950
 0.18
chr9_130624750_130625121 0.18 ENSG00000263979
 .
 6839
 0.08
chr1_158604437_158604588 0.18 OR10Z1
 olfactory receptor, family 10, subfamily Z, member 1
 28283
 0.13
chr16_16165629_16165805 0.18 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 62004
 0.12
chr1_36831464_36831995 0.18 STK40
 serine/threonine kinase 40
 4788
 0.15
chr13_108102676_108103085 0.18 ENSG00000221650
 .
 80716
 0.11
chr2_127912815_127913111 0.18 BIN1
 bridging integrator 1
 48032
 0.14
chr3_129280215_129280484 0.18 PLXND1
 plexin D1
 450
 0.78
chr7_102530812_102531077 0.18 LRRC17
 leucine rich repeat containing 17
 22494
 0.16
chr5_177869992_177870288 0.18 CTB-26E19.1
45
 0.98
chr7_101360762_101360997 0.18 MYL10
 myosin, light chain 10, regulatory
 88303
 0.08
chr17_47905442_47905593 0.18 RP11-304F15.3
17755
 0.14
chr1_17621907_17622242 0.18 PADI4
 peptidyl arginine deiminase, type IV
 12616
 0.15
chr19_14486268_14486999 0.18 CD97
 CD97 molecule
 5335
 0.16
chr22_33158107_33158258 0.18 LL22NC01-116C6.1
20981
 0.22
chr3_4518637_4518947 0.18 SUMF1
 sulfatase modifying factor 1
 9827
 0.2
chr14_71276457_71276666 0.17 MAP3K9
 mitogen-activated protein kinase kinase kinase 9
 310
 0.94
chr11_2763311_2763710 0.17 KCNQ1OT1
 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
 42286
 0.15
chr12_111873433_111874308 0.17 SH2B3
 SH2B adaptor protein 3
 1204
 0.47
chr6_114071112_114071516 0.17 ENSG00000253091
 .
 31353
 0.18
chr6_54453109_54453260 0.17 ENSG00000251946
 .
 198001
 0.03
chr10_14778907_14779278 0.17 FAM107B
 family with sequence similarity 107, member B
 37804
 0.16
chr11_118023633_118024140 0.17 SCN4B
 sodium channel, voltage-gated, type IV, beta subunit
 283
 0.88
chr6_89271446_89271597 0.17 ENSG00000222145
 .
 152628
 0.04
chr6_39771799_39772005 0.17 DAAM2
 dishevelled associated activator of morphogenesis 2
 11108
 0.26
chr20_30657043_30657343 0.17 HCK
 hemopoietic cell kinase
 17129
 0.12
chr11_130253658_130253916 0.17 ADAMTS8
 ADAM metallopeptidase with thrombospondin type 1 motif, 8
 45101
 0.15
chr11_66368217_66368514 0.17 CCS
 copper chaperone for superoxide dismutase
 860
 0.38
chr11_17877616_17877767 0.17 KCNC1
 potassium voltage-gated channel, Shaw-related subfamily, member 1
 120171
 0.05
chr2_189540640_189540876 0.17 GULP1
 GULP, engulfment adaptor PTB domain containing 1
 105948
 0.07
chr5_76598141_76598292 0.17 PDE8B
 phosphodiesterase 8B
 23302
 0.24
chr6_20028504_20028655 0.17 RP11-239H6.2
183739
 0.03
chr2_216764593_216764988 0.17 ENSG00000212055
 .
 21148
 0.25
chrX_135291994_135292627 0.17 FHL1
 four and a half LIM domains 1
 5430
 0.24
chr16_31037072_31037504 0.17 STX4
 syntaxin 4
 6922
 0.08
chr19_16556596_16556763 0.17 CTD-2013N17.4
4922
 0.15
chr21_41004853_41005004 0.17 AF064860.5
2730
 0.27
chr11_10347895_10348118 0.17 AMPD3
 adenosine monophosphate deaminase 3
 8788
 0.17
chr9_132096828_132097338 0.17 ENSG00000242281
 .
 35657
 0.16
chr17_59311556_59311803 0.17 RP11-136H19.1
98354
 0.06
chr7_5649047_5649443 0.17 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 14928
 0.16
chr5_77796055_77796354 0.17 LHFPL2
 lipoma HMGIC fusion partner-like 2
 48770
 0.18
chr15_78375318_78375576 0.17 SH2D7
 SH2 domain containing 7
 5297
 0.14
chr4_146702479_146702874 0.17 ZNF827
 zinc finger protein 827
 6857
 0.25
chr9_127025264_127025533 0.17 RP11-121A14.3
243
 0.88
chr20_48843010_48843216 0.17 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
 35737
 0.17
chr4_86853987_86854157 0.17 ARHGAP24
 Rho GTPase activating protein 24
 2646
 0.31
chr12_2468276_2468593 0.17 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 89492
 0.09
chr3_183025161_183025367 0.17 B3GNT5
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
 42132
 0.14
chr8_37660040_37660273 0.17 GPR124
 G protein-coupled receptor 124
 5382
 0.16
chr11_114006986_114007170 0.17 ENSG00000221112
 .
 49427
 0.14
chr18_54126758_54127059 0.17 TXNL1
 thioredoxin-like 1
 154814
 0.04
chr12_19727679_19727830 0.17 AEBP2
 AE binding protein 2
 74691
 0.12
chr9_79206598_79206788 0.17 ENSG00000241781
 .
 19962
 0.22
chr2_127862116_127862267 0.17 BIN1
 bridging integrator 1
 2386
 0.38
chr4_54552846_54552997 0.17 RP11-317M11.1
9147
 0.23
chr14_100240950_100241315 0.17 EML1
 echinoderm microtubule associated protein like 1
 1091
 0.59
chr10_75727518_75727836 0.17 VCL
 vinculin
 30195
 0.12
chr21_36277232_36277480 0.17 RUNX1
 runt-related transcription factor 1
 15269
 0.29
chr1_184120290_184120490 0.17 ENSG00000199840
 .
 20567
 0.24
chr1_21991980_21992494 0.17 RAP1GAP
 RAP1 GTPase activating protein
 3557
 0.26
chr1_39995674_39995906 0.17 RP11-69E11.4
4433
 0.16
chr10_134755869_134756456 0.17 TTC40
 tetratricopeptide repeat domain 40
 73
 0.98
chr15_63073163_63073722 0.17 ENSG00000265317
 .
 5564
 0.2
chr5_139041444_139041605 0.17 CXXC5
 CXXC finger protein 5
 2384
 0.32
chr17_40111299_40111636 0.17 CNP
 2',3'-cyclic nucleotide 3' phosphodiesterase
 7292
 0.12
chr19_18476603_18476927 0.17 PGPEP1
 pyroglutamyl-peptidase I
 8449
 0.09
chr6_37668651_37668857 0.17 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 1672
 0.48
chr6_43805886_43806228 0.17 VEGFA
 vascular endothelial growth factor A
 63967
 0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.3 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1 0.2 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.3 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.3 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060180 regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.0 0.1 GO:0032303 regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0032373 positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.3 GO:0050926 regulation of positive chemotaxis(GO:0050926)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.0 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.0 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.1 GO:0032206 positive regulation of telomere maintenance(GO:0032206)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.0 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.0 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0043205 fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.0 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.0 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism