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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for KLF13

Z-value: 1.02

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Transcription factors associated with KLF13

Gene Symbol	Gene ID	Gene Info
KLF13 Ensembl NCBI GeneCards UniProt	ENSG00000169926.5	KLF13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
KLF13	chr15_31619464_31619615	481	0.887517	0.90	8.1e-04	Click!
KLF13	chr15_31621843_31621994	2860	0.395501	0.86	3.1e-03	Click!
KLF13	chr15_31645569_31645720	12713	0.294014	0.86	3.2e-03	Click!
KLF13	chr15_31600904_31601060	18076	0.272251	0.85	3.7e-03	Click!
KLF13	chr15_31644683_31644849	12630	0.294151	0.83	5.2e-03	Click!

Activity of the KLF13 motif across conditions

Conditions sorted by the z-value of the KLF13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_7184802_7184953	0.73	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	109	0.88
chr1_161146927_161147078	0.51	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	273	0.76
chr19_46103286_46103456	0.51	GPR4	G protein-coupled receptor 4	2095	0.16
chr10_134265737_134265934	0.48	C10orf91	chromosome 10 open reading frame 91	7142	0.19
chr22_18269517_18269668	0.46	BID	BH3 interacting domain death agonist	12161	0.18
chr19_55952161_55952312	0.46	SHISA7	shisa family member 7	1468	0.21
chr9_131971017_131971168	0.44	RP11-247A12.2		7498	0.15
chr2_219258625_219258977	0.42	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	4260	0.1
chr6_6886561_6886823	0.41	ENSG00000240936	.	52438	0.17
chr2_71295991_71296142	0.40	NAGK	N-acetylglucosamine kinase	274	0.84
chr6_158993431_158993582	0.40	TMEM181	transmembrane protein 181	36038	0.15
chr15_99601132_99601283	0.40	SYNM	synemin, intermediate filament protein	37213	0.12
chr1_7130417_7130568	0.39	RP11-334N17.1		56153	0.15
chr5_171604379_171604532	0.37	STK10	serine/threonine kinase 10	10935	0.19
chr16_57174332_57174517	0.37	CPNE2	copine II	21313	0.13
chr18_5057426_5057577	0.36	ENSG00000222463	.	69333	0.13
chr19_18898466_18898690	0.36	COMP	cartilage oligomeric matrix protein	3536	0.19
chr2_740601_740858	0.35	AC092159.3		47494	0.15
chr19_49931671_49931926	0.35	GFY	golgi-associated, olfactory signaling regulator	4792	0.07
chr5_139487909_139488137	0.35	LINC01024	long intergenic non-protein coding RNA 1024	127	0.95
chr19_15580914_15581065	0.35	RASAL3	RAS protein activator like 3	5607	0.13
chr19_55972386_55972537	0.35	ISOC2	isochorismatase domain containing 2	475	0.62
chr1_68151591_68151742	0.35	GADD45A	growth arrest and DNA-damage-inducible, alpha	782	0.69
chr11_336653_336830	0.34	IFITM3	interferon induced transmembrane protein 3	9204	0.07
chr17_2696074_2696428	0.34	RAP1GAP2	RAP1 GTPase activating protein 2	3481	0.22
chr19_46144336_46144530	0.33	C19orf83	chromosome 19 open reading frame 83	516	0.5
chr20_3102729_3102880	0.33	UBOX5-AS1	UBOX5 antisense RNA 1	11521	0.11
chr2_85059019_85059256	0.33	TRABD2A	TraB domain containing 2A	49069	0.13
chr17_74493523_74493698	0.33	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	3843	0.12
chr15_64126438_64126618	0.32	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	387	0.89
chr20_61609083_61609372	0.32	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	24829	0.13
chr2_85153301_85153532	0.32	TMSB10	thymosin beta 10	20667	0.17
chr14_74416480_74416631	0.32	COQ6	coenzyme Q6 monooxygenase	74	0.75
chr6_37467874_37468104	0.32	CCDC167	coiled-coil domain containing 167	291	0.92
chr17_64962073_64962262	0.31	CACNG4	calcium channel, voltage-dependent, gamma subunit 4	1141	0.49
chr8_134508796_134508947	0.31	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	2733	0.41
chr6_15017519_15017967	0.31	ENSG00000242989	.	95456	0.09
chr14_75802560_75802738	0.30	FOS	FBJ murine osteosarcoma viral oncogene homolog	55753	0.1
chr10_6192977_6193257	0.30	ENSG00000263628	.	1042	0.38
chr2_16080025_16080176	0.30	MYCN	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	586	0.63
chr19_862652_862803	0.29	CFD	complement factor D (adipsin)	3037	0.11
chr13_50918820_50919100	0.29	ENSG00000221198	.	18413	0.28
chr3_37285712_37286013	0.29	RP11-259K5.2		194	0.89
chr14_93313883_93314055	0.29	GOLGA5	golgin A5	14498	0.25
chr3_158519751_158519902	0.29	MFSD1	major facilitator superfamily domain containing 1	54	0.56
chr1_1118104_1118264	0.28	TTLL10	tubulin tyrosine ligase-like family, member 10	3107	0.1
chr1_160684089_160684457	0.28	CD48	CD48 molecule	2632	0.23
chr17_72735203_72735698	0.28	RAB37	RAB37, member RAS oncogene family	2079	0.18
chr2_99364356_99364519	0.28	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	16848	0.2
chr8_11324526_11324725	0.28	FAM167A	family with sequence similarity 167, member A	349	0.85
chr10_62727947_62728098	0.28	RHOBTB1	Rho-related BTB domain containing 1	24017	0.24
chr1_90396399_90396550	0.28	ENSG00000252797	.	57029	0.13
chr8_142130442_142130593	0.27	DENND3	DENN/MADD domain containing 3	3140	0.26
chr3_196372798_196372949	0.27	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	6227	0.14
chr17_25870024_25870175	0.27	KSR1	kinase suppressor of ras 1	39848	0.15
chr17_47817453_47817604	0.27	FAM117A	family with sequence similarity 117, member A	15639	0.14
chr8_143385130_143385421	0.27	TSNARE1	t-SNARE domain containing 1	50849	0.13
chr8_82543299_82543455	0.26	IMPA1P	inositol(myo)-1(or 4)-monophosphatase 1 pseudogene	4193	0.23
chrX_129243058_129243209	0.26	ELF4	E74-like factor 4 (ets domain transcription factor)	1203	0.51
chr15_99258837_99259137	0.26	IGF1R	insulin-like growth factor 1 receptor	7927	0.26
chr15_75055139_75055425	0.26	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	14097	0.11
chr19_39971056_39971294	0.26	TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	123	0.92
chr1_26100922_26101094	0.26	SEPN1	selenoprotein N, 1	25659	0.11
chr11_118309485_118309636	0.26	KMT2A	lysine (K)-specific methyltransferase 2A	2083	0.18
chr14_104338342_104338493	0.25	PPP1R13B	protein phosphatase 1, regulatory subunit 13B	24490	0.13
chr9_131267547_131267753	0.25	GLE1	GLE1 RNA export mediator	565	0.62
chr19_10528216_10528367	0.25	PDE4A	phosphodiesterase 4A, cAMP-specific	672	0.52
chr11_61658320_61658531	0.25	FADS3	fatty acid desaturase 3	428	0.76
chr10_71078022_71078173	0.25	HK1	hexokinase 1	503	0.8
chr16_57177310_57177461	0.25	CPNE2	copine II	24274	0.12
chr3_69134778_69134936	0.24	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	685	0.62
chr17_46660068_46660219	0.24	HOXB3	homeobox B3	159	0.76
chr20_10530697_10531175	0.24	JAG1	jagged 1	112218	0.06
chr19_6261889_6262159	0.24	CTC-503J8.4		2856	0.2
chr19_18775251_18775402	0.24	CRTC1	CREB regulated transcription coactivator 1	19161	0.11
chr9_92063731_92064015	0.24	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	6995	0.26
chrX_153169917_153170068	0.23	AVPR2	arginine vasopressin receptor 2	197	0.87
chr16_58018074_58018383	0.23	TEPP	testis, prostate and placenta expressed	7889	0.13
chr14_105641458_105641667	0.23	NUDT14	nudix (nucleoside diphosphate linked moiety X)-type motif 14	6078	0.17
chrX_109543624_109543775	0.23	AMMECR1-IT1	AMMECR1 intronic transcript 1 (non-protein coding)	6750	0.2
chr18_43913133_43913284	0.23	RNF165	ring finger protein 165	723	0.78
chr2_60618463_60618614	0.23	ENSG00000266078	.	3958	0.27
chr10_94582178_94582340	0.23	EXOC6	exocyst complex component 6	8676	0.28
chr18_77450365_77450516	0.23	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	9591	0.23
chr10_74384901_74385052	0.22	MICU1	mitochondrial calcium uptake 1	860	0.57
chr19_900208_900359	0.22	ENSG00000207507	.	6799	0.08
chr20_58691613_58691835	0.22	C20orf197	chromosome 20 open reading frame 197	60744	0.14
chr1_221052508_221052659	0.22	HLX	H2.0-like homeobox	884	0.41
chr3_194354391_194354771	0.22	TMEM44	transmembrane protein 44	163	0.88
chr2_208364611_208364762	0.22	CREB1	cAMP responsive element binding protein 1	29775	0.18
chr4_141077881_141078032	0.22	MAML3	mastermind-like 3 (Drosophila)	2618	0.33
chr2_178937506_178937762	0.21	PDE11A	phosphodiesterase 11A	152	0.96
chr12_48357535_48357686	0.21	TMEM106C	transmembrane protein 106C	31	0.97
chr1_39665289_39665440	0.21	MACF1	microtubule-actin crosslinking factor 1	4554	0.2
chr11_124746668_124746852	0.21	ROBO3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	524	0.64
chr9_77567865_77568016	0.21	RP11-197P3.4		56	0.61
chr10_77168496_77168860	0.21	ENSG00000237149	.	5866	0.2
chr6_144607266_144607540	0.21	UTRN	utrophin	566	0.83
chr4_71599845_71600265	0.21	RUFY3	RUN and FYVE domain containing 3	8	0.97
chr1_167585648_167585802	0.21	RCSD1	RCSD domain containing 1	13605	0.19
chr8_144416616_144416856	0.21	TOP1MT	topoisomerase (DNA) I, mitochondrial	229	0.86
chr2_47175075_47175226	0.21	MCFD2	multiple coagulation factor deficiency 2	6156	0.16
chr15_86036305_86036456	0.21	AKAP13	A kinase (PRKA) anchor protein 13	50891	0.13
chr9_249028_249455	0.21	RP11-59O6.3		23761	0.16
chr20_60606558_60606856	0.21	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	24090	0.16
chr1_181059536_181059906	0.21	IER5	immediate early response 5	2083	0.37
chr12_109125460_109125611	0.20	CORO1C	coronin, actin binding protein, 1C	163	0.94
chr9_99775939_99776257	0.20	HIATL2	hippocampus abundant transcript-like 2	236	0.94
chr1_12148511_12148915	0.20	ENSG00000201135	.	10672	0.15
chr19_8213404_8213659	0.20	FBN3	fibrillin 3	222	0.93
chr11_74855211_74855408	0.20	CTD-2562J17.2		4116	0.2
chr4_42637963_42638114	0.20	ATP8A1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	21072	0.22
chr19_52148720_52148871	0.19	SIGLEC5	sialic acid binding Ig-like lectin 5	3	0.95
chr20_32255270_32255449	0.19	NECAB3	N-terminal EF-hand calcium binding protein 3	894	0.32
chr11_4107967_4108118	0.19	RRM1	ribonucleotide reductase M1	7997	0.2
chr19_55667901_55668169	0.19	TNNI3	troponin I type 3 (cardiac)	58	0.93
chr1_27945410_27945570	0.19	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog	5083	0.16
chr9_123659112_123659288	0.19	TRAF1	TNF receptor-associated factor 1	17650	0.17
chr11_59435711_59435871	0.19	PATL1	protein associated with topoisomerase II homolog 1 (yeast)	662	0.47
chr19_36236721_36236922	0.19	PSENEN	presenilin enhancer gamma secretase subunit	301	0.53
chr15_62683922_62684073	0.19	RP11-299H22.5		121118	0.05
chr19_19843996_19844147	0.19	ZNF14	zinc finger protein 14	165	0.94
chr3_42633530_42633694	0.19	SS18L2	synovial sarcoma translocation gene on chromosome 18-like 2	1314	0.33
chr16_75284233_75284384	0.19	BCAR1	breast cancer anti-estrogen resistance 1	444	0.77
chr22_20000686_20000837	0.18	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	3570	0.13
chr3_57581712_57581923	0.18	ARF4	ADP-ribosylation factor 4	1235	0.28
chr19_8657534_8657719	0.18	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	546	0.68
chr19_39616574_39617021	0.18	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	323	0.84
chr16_27879052_27879203	0.18	ENSG00000212382	.	4555	0.25
chr6_7161361_7161773	0.18	RP11-405O10.2		21749	0.17
chr6_7053651_7053882	0.18	ENSG00000251762	.	12987	0.24
chr10_73105302_73105453	0.18	ENSG00000238918	.	20292	0.18
chr11_117587082_117587362	0.18	DSCAML1	Down syndrome cell adhesion molecule like 1	80584	0.08
chr5_72744482_72744675	0.18	FOXD1	forkhead box D1	226	0.94
chr9_136924579_136924782	0.18	BRD3	bromodomain containing 3	3546	0.2
chr4_174113548_174113766	0.18	RP11-10K16.1		22854	0.17
chr2_7084781_7084993	0.18	RNF144A	ring finger protein 144A	11713	0.2
chr17_41173335_41173521	0.18	VAT1	vesicle amine transport 1	945	0.34
chr5_1315108_1315672	0.17	ENSG00000263670	.	5898	0.18
chr5_173145182_173145333	0.17	ENSG00000263401	.	11824	0.27
chr22_42304434_42304780	0.17	SHISA8	shisa family member 8	5963	0.1
chr19_19043290_19043516	0.17	HOMER3	homer homolog 3 (Drosophila)	6388	0.1
chr2_740027_740237	0.17	AC092159.3		46897	0.15
chrX_119150159_119150382	0.17	RP4-755D9.1		19931	0.17
chr5_139145540_139145730	0.17	PSD2	pleckstrin and Sec7 domain containing 2	29771	0.16
chrX_83443667_83443818	0.17	RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	809	0.74
chr14_100771176_100771436	0.17	SLC25A29	solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29	1472	0.2
chr16_84121193_84121344	0.17	MBTPS1	membrane-bound transcription factor peptidase, site 1	29132	0.11
chr10_50009128_50009364	0.17	WDFY4	WDFY family member 4	1537	0.47
chr1_16276231_16276382	0.17	ZBTB17	zinc finger and BTB domain containing 17	5383	0.16
chr1_232055123_232055279	0.17	DISC1-IT1	DISC1 intronic transcript 1 (non-protein coding)	6379	0.33
chr1_9136576_9136727	0.17	SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	3470	0.2
chr11_121315919_121316119	0.17	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	6893	0.25
chr6_14225312_14225463	0.17	ENSG00000238987	.	68694	0.13
chrX_153619109_153619401	0.17	RPL10	ribosomal protein L10	6240	0.08
chr4_186049872_186050054	0.17	ENSG00000265619	.	6487	0.2
chr2_9934112_9934263	0.17	TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	49296	0.14
chrX_103175016_103175167	0.17	LL0XNC01-116E7.2		960	0.43
chr2_160143487_160143638	0.17	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1	252	0.95
chr11_76860343_76860494	0.17	MYO7A	myosin VIIA	21070	0.19
chr2_114195746_114195897	0.16	CBWD2	COBW domain containing 2	481	0.76
chr16_88844539_88844690	0.16	PIEZO1	piezo-type mechanosensitive ion channel component 1	7005	0.09
chr10_85954017_85954268	0.16	CDHR1	cadherin-related family member 1	268	0.89
chr16_56622840_56623034	0.16	MT3	metallothionein 3	49	0.95
chr15_47958076_47958227	0.16	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	51044	0.14
chr21_37693189_37693340	0.16	AP000692.10		296	0.76
chr6_116937723_116937948	0.16	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)	48	0.97
chr19_41324095_41324416	0.16	EGLN2	egl-9 family hypoxia-inducible factor 2	11107	0.12
chr1_21655784_21655935	0.16	ECE1	endothelin converting enzyme 1	16138	0.2
chr11_115580446_115580732	0.16	ENSG00000239153	.	82686	0.11
chr6_150326385_150326536	0.16	RAET1K	retinoic acid early transcript 1K pseudogene	167	0.94
chr22_37614574_37614752	0.16	SSTR3	somatostatin receptor 3	6301	0.14
chr18_25755759_25755910	0.16	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	1576	0.58
chr1_154946234_154946385	0.16	SHC1	SHC (Src homology 2 domain containing) transforming protein 1	503	0.44
chr8_9414176_9414915	0.16	RP11-375N15.2		515	0.7
chr14_92997995_92998245	0.16	RIN3	Ras and Rab interactor 3	17972	0.26
chr1_155024637_155024788	0.16	ADAM15	ADAM metallopeptidase domain 15	884	0.33
chr1_156814971_156815214	0.16	INSRR	insulin receptor-related receptor	13718	0.12
chr3_32911345_32911496	0.16	TRIM71	tripartite motif containing 71, E3 ubiquitin protein ligase	51910	0.14
chr3_23792642_23792891	0.15	ENSG00000238672	.	16336	0.21
chr19_532690_532841	0.15	CDC34	cell division cycle 34	705	0.48
chr19_55951851_55952002	0.15	SHISA7	shisa family member 7	1778	0.17
chr1_226257523_226257818	0.15	H3F3A	H3 histone, family 3A	5992	0.18
chr22_39485961_39486281	0.15	RP4-742C19.12		1470	0.3
chr8_143139430_143139581	0.15	ENSG00000221123	.	112645	0.06
chr19_18700873_18701059	0.15	C19orf60	chromosome 19 open reading frame 60	554	0.55
chr7_138917063_138917328	0.15	UBN2	ubinuclein 2	964	0.61
chr12_4550645_4550796	0.15	FGF6	fibroblast growth factor 6	2665	0.31
chr15_29561283_29561435	0.15	NDNL2	necdin-like 2	674	0.77
chr1_2226282_2226433	0.15	RP4-713A8.1		31775	0.1
chr12_110799070_110799221	0.15	ENSG00000264626	.	594	0.71
chr17_16697326_16697519	0.15	USP32P1	ubiquitin specific peptidase 32 pseudogene 1	1935	0.24
chr2_101991834_101991985	0.15	CREG2	cellular repressor of E1A-stimulated genes 2	12148	0.22
chr16_31404523_31404674	0.15	ITGAD	integrin, alpha D	35	0.96
chr12_282069_282229	0.15	RP11-598F7.5		6662	0.14
chr19_42723833_42723998	0.15	DEDD2	death effector domain containing 2	360	0.53
chr17_46521887_46522400	0.15	SKAP1	src kinase associated phosphoprotein 1	14562	0.13
chr12_131706127_131706426	0.15	AC092850.1	Protein LOC100996701	73791	0.11
chr4_109572628_109573042	0.15	ENSG00000206601	.	471	0.69
chr11_18742754_18742995	0.14	IGSF22	immunoglobulin superfamily, member 22	4853	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.2	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.3	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.2	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0072143	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.3	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.2	GO:0001836	release of cytochrome c from mitochondria(GO:0001836)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.3	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.0	0.0	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.2	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.4	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.6	GO:0051015	actin filament binding(GO:0051015)
0.0	0.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse