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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for KLF13

Z-value: 1.02

Motif logo

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Transcription factors associated with KLF13

Gene Symbol Gene ID Gene Info
KLF13
ENSG00000169926.5 Kruppel like factor 13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_31619464_31619615KLF134810.8875170.908.1e-04Click!
chr15_31621843_31621994KLF1328600.3955010.863.1e-03Click!
chr15_31645569_31645720KLF13127130.2940140.863.2e-03Click!
chr15_31600904_31601060KLF13180760.2722510.853.7e-03Click!
chr15_31644683_31644849KLF13126300.2941510.835.2e-03Click!

Activity of the KLF13 motif across conditions

Conditions sorted by the z-value of the KLF13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_7184802_7184953 0.73 SLC2A4
 solute carrier family 2 (facilitated glucose transporter), member 4
 109
 0.88
chr1_161146927_161147078 0.51 B4GALT3
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
 273
 0.76
chr19_46103286_46103456 0.51 GPR4
 G protein-coupled receptor 4
 2095
 0.16
chr10_134265737_134265934 0.48 C10orf91
 chromosome 10 open reading frame 91
 7142
 0.19
chr22_18269517_18269668 0.46 BID
 BH3 interacting domain death agonist
 12161
 0.18
chr19_55952161_55952312 0.46 SHISA7
 shisa family member 7
 1468
 0.21
chr9_131971017_131971168 0.44 RP11-247A12.2
7498
 0.15
chr2_219258625_219258977 0.42 CTDSP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
 4260
 0.1
chr6_6886561_6886823 0.41 ENSG00000240936
 .
 52438
 0.17
chr2_71295991_71296142 0.40 NAGK
 N-acetylglucosamine kinase
 274
 0.84
chr6_158993431_158993582 0.40 TMEM181
 transmembrane protein 181
 36038
 0.15
chr15_99601132_99601283 0.40 SYNM
 synemin, intermediate filament protein
 37213
 0.12
chr1_7130417_7130568 0.39 RP11-334N17.1
56153
 0.15
chr5_171604379_171604532 0.37 STK10
 serine/threonine kinase 10
 10935
 0.19
chr16_57174332_57174517 0.37 CPNE2
 copine II
 21313
 0.13
chr18_5057426_5057577 0.36 ENSG00000222463
 .
 69333
 0.13
chr19_18898466_18898690 0.36 COMP
 cartilage oligomeric matrix protein
 3536
 0.19
chr2_740601_740858 0.35 AC092159.3
47494
 0.15
chr19_49931671_49931926 0.35 GFY
 golgi-associated, olfactory signaling regulator
 4792
 0.07
chr5_139487909_139488137 0.35 LINC01024
 long intergenic non-protein coding RNA 1024
 127
 0.95
chr19_15580914_15581065 0.35 RASAL3
 RAS protein activator like 3
 5607
 0.13
chr19_55972386_55972537 0.35 ISOC2
 isochorismatase domain containing 2
 475
 0.62
chr1_68151591_68151742 0.35 GADD45A
 growth arrest and DNA-damage-inducible, alpha
 782
 0.69
chr11_336653_336830 0.34 IFITM3
 interferon induced transmembrane protein 3
 9204
 0.07
chr17_2696074_2696428 0.34 RAP1GAP2
 RAP1 GTPase activating protein 2
 3481
 0.22
chr19_46144336_46144530 0.33 C19orf83
 chromosome 19 open reading frame 83
 516
 0.5
chr20_3102729_3102880 0.33 UBOX5-AS1
 UBOX5 antisense RNA 1
 11521
 0.11
chr2_85059019_85059256 0.33 TRABD2A
 TraB domain containing 2A
 49069
 0.13
chr17_74493523_74493698 0.33 RHBDF2
 rhomboid 5 homolog 2 (Drosophila)
 3843
 0.12
chr15_64126438_64126618 0.32 HERC1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
 387
 0.89
chr20_61609083_61609372 0.32 SLC17A9
 solute carrier family 17 (vesicular nucleotide transporter), member 9
 24829
 0.13
chr2_85153301_85153532 0.32 TMSB10
 thymosin beta 10
 20667
 0.17
chr14_74416480_74416631 0.32 COQ6
 coenzyme Q6 monooxygenase
 74
 0.75
chr6_37467874_37468104 0.32 CCDC167
 coiled-coil domain containing 167
 291
 0.92
chr17_64962073_64962262 0.31 CACNG4
 calcium channel, voltage-dependent, gamma subunit 4
 1141
 0.49
chr8_134508796_134508947 0.31 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2733
 0.41
chr6_15017519_15017967 0.31 ENSG00000242989
 .
 95456
 0.09
chr14_75802560_75802738 0.30 FOS
 FBJ murine osteosarcoma viral oncogene homolog
 55753
 0.1
chr10_6192977_6193257 0.30 ENSG00000263628
 .
 1042
 0.38
chr2_16080025_16080176 0.30 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
 586
 0.63
chr19_862652_862803 0.29 CFD
 complement factor D (adipsin)
 3037
 0.11
chr13_50918820_50919100 0.29 ENSG00000221198
 .
 18413
 0.28
chr3_37285712_37286013 0.29 RP11-259K5.2
194
 0.89
chr14_93313883_93314055 0.29 GOLGA5
 golgin A5
 14498
 0.25
chr3_158519751_158519902 0.29 MFSD1
 major facilitator superfamily domain containing 1
 54
 0.56
chr1_1118104_1118264 0.28 TTLL10
 tubulin tyrosine ligase-like family, member 10
 3107
 0.1
chr1_160684089_160684457 0.28 CD48
 CD48 molecule
 2632
 0.23
chr17_72735203_72735698 0.28 RAB37
 RAB37, member RAS oncogene family
 2079
 0.18
chr2_99364356_99364519 0.28 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 16848
 0.2
chr8_11324526_11324725 0.28 FAM167A
 family with sequence similarity 167, member A
 349
 0.85
chr10_62727947_62728098 0.28 RHOBTB1
 Rho-related BTB domain containing 1
 24017
 0.24
chr1_90396399_90396550 0.28 ENSG00000252797
 .
 57029
 0.13
chr8_142130442_142130593 0.27 DENND3
 DENN/MADD domain containing 3
 3140
 0.26
chr3_196372798_196372949 0.27 PIGX
 phosphatidylinositol glycan anchor biosynthesis, class X
 6227
 0.14
chr17_25870024_25870175 0.27 KSR1
 kinase suppressor of ras 1
 39848
 0.15
chr17_47817453_47817604 0.27 FAM117A
 family with sequence similarity 117, member A
 15639
 0.14
chr8_143385130_143385421 0.27 TSNARE1
 t-SNARE domain containing 1
 50849
 0.13
chr8_82543299_82543455 0.26 IMPA1P
 inositol(myo)-1(or 4)-monophosphatase 1 pseudogene
 4193
 0.23
chrX_129243058_129243209 0.26 ELF4
 E74-like factor 4 (ets domain transcription factor)
 1203
 0.51
chr15_99258837_99259137 0.26 IGF1R
 insulin-like growth factor 1 receptor
 7927
 0.26
chr15_75055139_75055425 0.26 CYP1A2
 cytochrome P450, family 1, subfamily A, polypeptide 2
 14097
 0.11
chr19_39971056_39971294 0.26 TIMM50
 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
 123
 0.92
chr1_26100922_26101094 0.26 SEPN1
 selenoprotein N, 1
 25659
 0.11
chr11_118309485_118309636 0.26 KMT2A
 lysine (K)-specific methyltransferase 2A
 2083
 0.18
chr14_104338342_104338493 0.25 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 24490
 0.13
chr9_131267547_131267753 0.25 GLE1
 GLE1 RNA export mediator
 565
 0.62
chr19_10528216_10528367 0.25 PDE4A
 phosphodiesterase 4A, cAMP-specific
 672
 0.52
chr11_61658320_61658531 0.25 FADS3
 fatty acid desaturase 3
 428
 0.76
chr10_71078022_71078173 0.25 HK1
 hexokinase 1
 503
 0.8
chr16_57177310_57177461 0.25 CPNE2
 copine II
 24274
 0.12
chr3_69134778_69134936 0.24 ARL6IP5
 ADP-ribosylation-like factor 6 interacting protein 5
 685
 0.62
chr17_46660068_46660219 0.24 HOXB3
 homeobox B3
 159
 0.76
chr20_10530697_10531175 0.24 JAG1
 jagged 1
 112218
 0.06
chr19_6261889_6262159 0.24 CTC-503J8.4
2856
 0.2
chr19_18775251_18775402 0.24 CRTC1
 CREB regulated transcription coactivator 1
 19161
 0.11
chr9_92063731_92064015 0.24 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 6995
 0.26
chrX_153169917_153170068 0.23 AVPR2
 arginine vasopressin receptor 2
 197
 0.87
chr16_58018074_58018383 0.23 TEPP
 testis, prostate and placenta expressed
 7889
 0.13
chr14_105641458_105641667 0.23 NUDT14
 nudix (nucleoside diphosphate linked moiety X)-type motif 14
 6078
 0.17
chrX_109543624_109543775 0.23 AMMECR1-IT1
 AMMECR1 intronic transcript 1 (non-protein coding)
 6750
 0.2
chr18_43913133_43913284 0.23 RNF165
 ring finger protein 165
 723
 0.78
chr2_60618463_60618614 0.23 ENSG00000266078
 .
 3958
 0.27
chr10_94582178_94582340 0.23 EXOC6
 exocyst complex component 6
 8676
 0.28
chr18_77450365_77450516 0.23 CTDP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
 9591
 0.23
chr10_74384901_74385052 0.22 MICU1
 mitochondrial calcium uptake 1
 860
 0.57
chr19_900208_900359 0.22 ENSG00000207507
 .
 6799
 0.08
chr20_58691613_58691835 0.22 C20orf197
 chromosome 20 open reading frame 197
 60744
 0.14
chr1_221052508_221052659 0.22 HLX
 H2.0-like homeobox
 884
 0.41
chr3_194354391_194354771 0.22 TMEM44
 transmembrane protein 44
 163
 0.88
chr2_208364611_208364762 0.22 CREB1
 cAMP responsive element binding protein 1
 29775
 0.18
chr4_141077881_141078032 0.22 MAML3
 mastermind-like 3 (Drosophila)
 2618
 0.33
chr2_178937506_178937762 0.21 PDE11A
 phosphodiesterase 11A
 152
 0.96
chr12_48357535_48357686 0.21 TMEM106C
 transmembrane protein 106C
 31
 0.97
chr1_39665289_39665440 0.21 MACF1
 microtubule-actin crosslinking factor 1
 4554
 0.2
chr11_124746668_124746852 0.21 ROBO3
 roundabout, axon guidance receptor, homolog 3 (Drosophila)
 524
 0.64
chr9_77567865_77568016 0.21 RP11-197P3.4
56
 0.61
chr10_77168496_77168860 0.21 ENSG00000237149
 .
 5866
 0.2
chr6_144607266_144607540 0.21 UTRN
 utrophin
 566
 0.83
chr4_71599845_71600265 0.21 RUFY3
 RUN and FYVE domain containing 3
 8
 0.97
chr1_167585648_167585802 0.21 RCSD1
 RCSD domain containing 1
 13605
 0.19
chr8_144416616_144416856 0.21 TOP1MT
 topoisomerase (DNA) I, mitochondrial
 229
 0.86
chr2_47175075_47175226 0.21 MCFD2
 multiple coagulation factor deficiency 2
 6156
 0.16
chr15_86036305_86036456 0.21 AKAP13
 A kinase (PRKA) anchor protein 13
 50891
 0.13
chr9_249028_249455 0.21 RP11-59O6.3
23761
 0.16
chr20_60606558_60606856 0.21 TAF4
 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
 24090
 0.16
chr1_181059536_181059906 0.21 IER5
 immediate early response 5
 2083
 0.37
chr12_109125460_109125611 0.20 CORO1C
 coronin, actin binding protein, 1C
 163
 0.94
chr9_99775939_99776257 0.20 HIATL2
 hippocampus abundant transcript-like 2
 236
 0.94
chr1_12148511_12148915 0.20 ENSG00000201135
 .
 10672
 0.15
chr19_8213404_8213659 0.20 FBN3
 fibrillin 3
 222
 0.93
chr11_74855211_74855408 0.20 CTD-2562J17.2
4116
 0.2
chr4_42637963_42638114 0.20 ATP8A1
 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
 21072
 0.22
chr19_52148720_52148871 0.19 SIGLEC5
 sialic acid binding Ig-like lectin 5
 3
 0.95
chr20_32255270_32255449 0.19 NECAB3
 N-terminal EF-hand calcium binding protein 3
 894
 0.32
chr11_4107967_4108118 0.19 RRM1
 ribonucleotide reductase M1
 7997
 0.2
chr19_55667901_55668169 0.19 TNNI3
 troponin I type 3 (cardiac)
 58
 0.93
chr1_27945410_27945570 0.19 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 5083
 0.16
chr9_123659112_123659288 0.19 TRAF1
 TNF receptor-associated factor 1
 17650
 0.17
chr11_59435711_59435871 0.19 PATL1
 protein associated with topoisomerase II homolog 1 (yeast)
 662
 0.47
chr19_36236721_36236922 0.19 PSENEN
 presenilin enhancer gamma secretase subunit
 301
 0.53
chr15_62683922_62684073 0.19 RP11-299H22.5
121118
 0.05
chr19_19843996_19844147 0.19 ZNF14
 zinc finger protein 14
 165
 0.94
chr3_42633530_42633694 0.19 SS18L2
 synovial sarcoma translocation gene on chromosome 18-like 2
 1314
 0.33
chr16_75284233_75284384 0.19 BCAR1
 breast cancer anti-estrogen resistance 1
 444
 0.77
chr22_20000686_20000837 0.18 ARVCF
 armadillo repeat gene deleted in velocardiofacial syndrome
 3570
 0.13
chr3_57581712_57581923 0.18 ARF4
 ADP-ribosylation factor 4
 1235
 0.28
chr19_8657534_8657719 0.18 ADAMTS10
 ADAM metallopeptidase with thrombospondin type 1 motif, 10
 546
 0.68
chr19_39616574_39617021 0.18 PAK4
 p21 protein (Cdc42/Rac)-activated kinase 4
 323
 0.84
chr16_27879052_27879203 0.18 ENSG00000212382
 .
 4555
 0.25
chr6_7161361_7161773 0.18 RP11-405O10.2
21749
 0.17
chr6_7053651_7053882 0.18 ENSG00000251762
 .
 12987
 0.24
chr10_73105302_73105453 0.18 ENSG00000238918
 .
 20292
 0.18
chr11_117587082_117587362 0.18 DSCAML1
 Down syndrome cell adhesion molecule like 1
 80584
 0.08
chr5_72744482_72744675 0.18 FOXD1
 forkhead box D1
 226
 0.94
chr9_136924579_136924782 0.18 BRD3
 bromodomain containing 3
 3546
 0.2
chr4_174113548_174113766 0.18 RP11-10K16.1
22854
 0.17
chr2_7084781_7084993 0.18 RNF144A
 ring finger protein 144A
 11713
 0.2
chr17_41173335_41173521 0.18 VAT1
 vesicle amine transport 1
 945
 0.34
chr5_1315108_1315672 0.17 ENSG00000263670
 .
 5898
 0.18
chr5_173145182_173145333 0.17 ENSG00000263401
 .
 11824
 0.27
chr22_42304434_42304780 0.17 SHISA8
 shisa family member 8
 5963
 0.1
chr19_19043290_19043516 0.17 HOMER3
 homer homolog 3 (Drosophila)
 6388
 0.1
chr2_740027_740237 0.17 AC092159.3
46897
 0.15
chrX_119150159_119150382 0.17 RP4-755D9.1
19931
 0.17
chr5_139145540_139145730 0.17 PSD2
 pleckstrin and Sec7 domain containing 2
 29771
 0.16
chrX_83443667_83443818 0.17 RPS6KA6
 ribosomal protein S6 kinase, 90kDa, polypeptide 6
 809
 0.74
chr14_100771176_100771436 0.17 SLC25A29
 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
 1472
 0.2
chr16_84121193_84121344 0.17 MBTPS1
 membrane-bound transcription factor peptidase, site 1
 29132
 0.11
chr10_50009128_50009364 0.17 WDFY4
 WDFY family member 4
 1537
 0.47
chr1_16276231_16276382 0.17 ZBTB17
 zinc finger and BTB domain containing 17
 5383
 0.16
chr1_232055123_232055279 0.17 DISC1-IT1
 DISC1 intronic transcript 1 (non-protein coding)
 6379
 0.33
chr1_9136576_9136727 0.17 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
 3470
 0.2
chr11_121315919_121316119 0.17 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 6893
 0.25
chr6_14225312_14225463 0.17 ENSG00000238987
 .
 68694
 0.13
chrX_153619109_153619401 0.17 RPL10
 ribosomal protein L10
 6240
 0.08
chr4_186049872_186050054 0.17 ENSG00000265619
 .
 6487
 0.2
chr2_9934112_9934263 0.17 TAF1B
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
 49296
 0.14
chrX_103175016_103175167 0.17 LL0XNC01-116E7.2
960
 0.43
chr2_160143487_160143638 0.17 WDSUB1
 WD repeat, sterile alpha motif and U-box domain containing 1
 252
 0.95
chr11_76860343_76860494 0.17 MYO7A
 myosin VIIA
 21070
 0.19
chr2_114195746_114195897 0.16 CBWD2
 COBW domain containing 2
 481
 0.76
chr16_88844539_88844690 0.16 PIEZO1
 piezo-type mechanosensitive ion channel component 1
 7005
 0.09
chr10_85954017_85954268 0.16 CDHR1
 cadherin-related family member 1
 268
 0.89
chr16_56622840_56623034 0.16 MT3
 metallothionein 3
 49
 0.95
chr15_47958076_47958227 0.16 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 51044
 0.14
chr21_37693189_37693340 0.16 AP000692.10
296
 0.76
chr6_116937723_116937948 0.16 RSPH4A
 radial spoke head 4 homolog A (Chlamydomonas)
 48
 0.97
chr19_41324095_41324416 0.16 EGLN2
 egl-9 family hypoxia-inducible factor 2
 11107
 0.12
chr1_21655784_21655935 0.16 ECE1
 endothelin converting enzyme 1
 16138
 0.2
chr11_115580446_115580732 0.16 ENSG00000239153
 .
 82686
 0.11
chr6_150326385_150326536 0.16 RAET1K
 retinoic acid early transcript 1K pseudogene
 167
 0.94
chr22_37614574_37614752 0.16 SSTR3
 somatostatin receptor 3
 6301
 0.14
chr18_25755759_25755910 0.16 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 1576
 0.58
chr1_154946234_154946385 0.16 SHC1
 SHC (Src homology 2 domain containing) transforming protein 1
 503
 0.44
chr8_9414176_9414915 0.16 RP11-375N15.2
515
 0.7
chr14_92997995_92998245 0.16 RIN3
 Ras and Rab interactor 3
 17972
 0.26
chr1_155024637_155024788 0.16 ADAM15
 ADAM metallopeptidase domain 15
 884
 0.33
chr1_156814971_156815214 0.16 INSRR
 insulin receptor-related receptor
 13718
 0.12
chr3_32911345_32911496 0.16 TRIM71
 tripartite motif containing 71, E3 ubiquitin protein ligase
 51910
 0.14
chr3_23792642_23792891 0.15 ENSG00000238672
 .
 16336
 0.21
chr19_532690_532841 0.15 CDC34
 cell division cycle 34
 705
 0.48
chr19_55951851_55952002 0.15 SHISA7
 shisa family member 7
 1778
 0.17
chr1_226257523_226257818 0.15 H3F3A
 H3 histone, family 3A
 5992
 0.18
chr22_39485961_39486281 0.15 RP4-742C19.12
1470
 0.3
chr8_143139430_143139581 0.15 ENSG00000221123
 .
 112645
 0.06
chr19_18700873_18701059 0.15 C19orf60
 chromosome 19 open reading frame 60
 554
 0.55
chr7_138917063_138917328 0.15 UBN2
 ubinuclein 2
 964
 0.61
chr12_4550645_4550796 0.15 FGF6
 fibroblast growth factor 6
 2665
 0.31
chr15_29561283_29561435 0.15 NDNL2
 necdin-like 2
 674
 0.77
chr1_2226282_2226433 0.15 RP4-713A8.1
31775
 0.1
chr12_110799070_110799221 0.15 ENSG00000264626
 .
 594
 0.71
chr17_16697326_16697519 0.15 USP32P1
 ubiquitin specific peptidase 32 pseudogene 1
 1935
 0.24
chr2_101991834_101991985 0.15 CREG2
 cellular repressor of E1A-stimulated genes 2
 12148
 0.22
chr16_31404523_31404674 0.15 ITGAD
 integrin, alpha D
 35
 0.96
chr12_282069_282229 0.15 RP11-598F7.5
6662
 0.14
chr19_42723833_42723998 0.15 DEDD2
 death effector domain containing 2
 360
 0.53
chr17_46521887_46522400 0.15 SKAP1
 src kinase associated phosphoprotein 1
 14562
 0.13
chr12_131706127_131706426 0.15 AC092850.1
 Protein LOC100996701
 73791
 0.11
chr4_109572628_109573042 0.15 ENSG00000206601
 .
 471
 0.69
chr11_18742754_18742995 0.14 IGSF22
 immunoglobulin superfamily, member 22
 4853
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 0.2 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0072143 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0015809 arginine transport(GO:0015809)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0016246 RNA interference(GO:0016246)
0.0 0.3 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.1 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse