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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for KLF14_SP8

Z-value: 2.03

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Transcription factors associated with KLF14_SP8

Gene Symbol	Gene ID	Gene Info
KLF14 Ensembl NCBI GeneCards UniProt	ENSG00000174595.4	Kruppel like factor 14
SP8 Ensembl NCBI GeneCards UniProt	ENSG00000164651.12	Sp8 transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_130419715_130419866	KLF14	902	0.642700	0.66	5.3e-02	Click!
chr7_130427792_130427943	KLF14	8979	0.231836	0.45	2.2e-01	Click!
chr7_130418289_130418568	KLF14	460	0.849732	0.31	4.1e-01	Click!
chr7_130419123_130419274	KLF14	310	0.916207	0.31	4.2e-01	Click!
chr7_130419356_130419681	KLF14	630	0.767444	0.20	6.1e-01	Click!
chr7_20876550_20876701	SP8	50120	0.187855	-0.65	5.9e-02	Click!
chr7_20836375_20836526	SP8	9945	0.313975	0.59	9.7e-02	Click!
chr7_20950795_20950946	SP8	124365	0.061043	-0.56	1.1e-01	Click!
chr7_20936732_20936883	SP8	110302	0.073815	0.48	1.9e-01	Click!
chr7_21003725_21003876	SP8	177295	0.033174	0.44	2.4e-01	Click!

Activity of the KLF14_SP8 motif across conditions

Conditions sorted by the z-value of the KLF14_SP8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_27879052_27879203	2.00	ENSG00000212382	.	4555	0.25
chr2_740601_740858	1.96	AC092159.3		47494	0.15
chr4_1617240_1617391	1.28	FAM53A	family with sequence similarity 53, member A	39820	0.14
chr22_39485961_39486281	0.91	RP4-742C19.12		1470	0.3
chr20_58691613_58691835	0.90	C20orf197	chromosome 20 open reading frame 197	60744	0.14
chr12_58165549_58165734	0.88	METTL1	methyltransferase like 1	261	0.49
chr19_900208_900359	0.86	ENSG00000207507	.	6799	0.08
chr2_740331_740594	0.86	AC092159.3		47227	0.15
chr7_100609089_100609240	0.81	ENSG00000225946	.	1317	0.33
chrX_154236957_154237108	0.76	F8	coagulation factor VIII, procoagulant component	13996	0.15
chr19_8657534_8657719	0.72	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	546	0.68
chr20_3055475_3055737	0.70	OXT	oxytocin/neurophysin I prepropeptide	3340	0.15
chrX_153169917_153170068	0.69	AVPR2	arginine vasopressin receptor 2	197	0.87
chr2_740027_740237	0.67	AC092159.3		46897	0.15
chr16_89259254_89259405	0.65	SLC22A31	solute carrier family 22, member 31	8743	0.12
chr11_128493152_128493455	0.64	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	35850	0.16
chr17_8090983_8091134	0.64	ENSG00000266638	.	565	0.51
chr16_67719327_67719733	0.63	C16orf86	chromosome 16 open reading frame 86	18737	0.09
chr19_8657183_8657409	0.63	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	216	0.9
chr1_158768566_158768717	0.61	OR6N2	olfactory receptor, family 6, subfamily N, member 2	21216	0.14
chr5_173145182_173145333	0.60	ENSG00000263401	.	11824	0.27
chr11_57406323_57406488	0.60	AP000662.4		556	0.59
chr11_1864542_1864693	0.59	TNNI2	troponin I type 2 (skeletal, fast)	3193	0.13
chr15_82336812_82337149	0.59	ENSG00000222521	.	345	0.84
chr17_7184802_7184953	0.57	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	109	0.88
chr16_58028490_58028941	0.56	USB1	U6 snRNA biogenesis 1	4735	0.14
chr19_3573938_3574224	0.56	MFSD12	major facilitator superfamily domain containing 12	454	0.59
chr14_91720187_91720656	0.56	GPR68	G protein-coupled receptor 68	152	0.95
chr21_45574456_45574750	0.55	C21orf33	chromosome 21 open reading frame 33	18602	0.13
chr19_14800378_14800529	0.55	ZNF333	zinc finger protein 333	258	0.61
chr16_86600319_86600625	0.54	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	385	0.71
chr16_84640133_84640303	0.52	COTL1	coactosin-like 1 (Dictyostelium)	11447	0.16
chr10_29971037_29971284	0.52	ENSG00000222092	.	29684	0.19
chr17_13984270_13984421	0.52	COX10	cytochrome c oxidase assembly homolog 10 (yeast)	11424	0.22
chr3_126422896_126423047	0.52	CHCHD6	coiled-coil-helix-coiled-coil-helix domain containing 6	92	0.98
chr1_26873768_26874073	0.51	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	1577	0.3
chr19_51228108_51228259	0.51	CLEC11A	C-type lectin domain family 11, member A	1403	0.27
chr16_2028815_2028966	0.51	NOXO1	NADPH oxidase organizer 1	2294	0.08
chr3_126184777_126184928	0.51	ZXDC	ZXD family zinc finger C	9856	0.17
chr19_54402117_54402268	0.51	CACNG7	calcium channel, voltage-dependent, gamma subunit 7	10397	0.08
chr12_54757135_54757286	0.50	GPR84	G protein-coupled receptor 84	1048	0.3
chr17_62008717_62009009	0.49	CD79B	CD79b molecule, immunoglobulin-associated beta	758	0.5
chr17_1617960_1618191	0.49	ENSG00000186594	.	790	0.41
chr17_1106444_1106595	0.48	ABR	active BCR-related	15903	0.17
chr9_103190061_103190338	0.47	MSANTD3	Myb/SANT-like DNA-binding domain containing 3	480	0.78
chr7_99752786_99752937	0.47	C7orf43	chromosome 7 open reading frame 43	1202	0.18
chr19_4069404_4069640	0.47	ZBTB7A	zinc finger and BTB domain containing 7A	2579	0.17
chr17_17109981_17110277	0.47	PLD6	phospholipase D family, member 6	500	0.69
chr19_7771578_7772024	0.46	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	4769	0.1
chr19_36334847_36334998	0.46	NPHS1	nephrosis 1, congenital, Finnish type (nephrin)	7817	0.09
chr13_52496343_52496494	0.45	ATP7B	ATPase, Cu++ transporting, beta polypeptide	39633	0.15
chr1_154297413_154297726	0.45	ATP8B2	ATPase, aminophospholipid transporter, class I, type 8B, member 2	460	0.66
chr19_17873647_17873798	0.44	FCHO1	FCH domain only 1	210	0.91
chr3_48411931_48412082	0.43	FBXW12	F-box and WD repeat domain containing 12	1703	0.23
chr1_23853235_23853583	0.43	E2F2	E2F transcription factor 2	4303	0.21
chr19_49931671_49931926	0.43	GFY	golgi-associated, olfactory signaling regulator	4792	0.07
chr9_95892460_95892611	0.43	NINJ1	ninjurin 1	4035	0.2
chr11_75946941_75947092	0.43	WNT11	wingless-type MMTV integration site family, member 11	25236	0.18
chr20_61609083_61609372	0.43	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	24829	0.13
chr11_64479576_64479837	0.42	NRXN2	neurexin 2	511	0.73
chr19_46296144_46296295	0.42	DMWD	dystrophia myotonica, WD repeat containing	159	0.89
chr12_122092000_122092151	0.42	MORN3	MORN repeat containing 3	15485	0.16
chr2_219258625_219258977	0.42	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	4260	0.1
chr15_91967474_91967944	0.42	SV2B	synaptic vesicle glycoprotein 2B	198609	0.03
chr19_40871650_40871801	0.41	PLD3	phospholipase D family, member 3	176	0.9
chr6_2651867_2652018	0.41	C6orf195	chromosome 6 open reading frame 195	17105	0.25
chr15_99387637_99387788	0.41	IGF1R	insulin-like growth factor 1 receptor	45858	0.14
chr11_117666974_117667125	0.41	DSCAML1	Down syndrome cell adhesion molecule like 1	757	0.61
chr17_72735203_72735698	0.41	RAB37	RAB37, member RAS oncogene family	2079	0.18
chr1_228247522_228247860	0.41	ARF1	ADP-ribosylation factor 1	22670	0.12
chr9_139237366_139237517	0.40	GPSM1	G-protein signaling modulator 1	8536	0.12
chr15_62683922_62684073	0.40	RP11-299H22.5		121118	0.05
chr17_43045837_43045988	0.40	C1QL1	complement component 1, q subcomponent-like 1	473	0.72
chr16_727350_727692	0.39	RHBDL1	rhomboid, veinlet-like 1 (Drosophila)	1446	0.13
chr19_1064402_1064702	0.39	HMHA1	histocompatibility (minor) HA-1	1370	0.23
chr19_50093322_50093473	0.39	NOSIP	nitric oxide synthase interacting protein	122	0.89
chr15_74003742_74003893	0.38	CD276	CD276 molecule	7567	0.23
chr20_10530697_10531175	0.38	JAG1	jagged 1	112218	0.06
chr22_39923418_39924173	0.38	RPS19BP1	ribosomal protein S19 binding protein 1	5065	0.16
chr8_25153086_25153237	0.38	DOCK5	dedicator of cytokinesis 5	3297	0.35
chr5_176862091_176862242	0.37	GRK6	G protein-coupled receptor kinase 6	8311	0.09
chr3_57581712_57581923	0.37	ARF4	ADP-ribosylation factor 4	1235	0.28
chr11_76341070_76341548	0.37	AP001189.4		26791	0.16
chr17_78785304_78785677	0.37	RP11-28G8.1		6058	0.26
chr12_56546362_56546609	0.36	MYL6B	myosin, light chain 6B, alkali, smooth muscle and non-muscle	94	0.9
chr11_118309485_118309636	0.35	KMT2A	lysine (K)-specific methyltransferase 2A	2083	0.18
chr13_21750174_21750509	0.35	SKA3	spindle and kinetochore associated complex subunit 3	345	0.55
chr11_65545992_65546157	0.35	AP5B1	adaptor-related protein complex 5, beta 1 subunit	2199	0.16
chr19_18544394_18544545	0.35	SSBP4	single stranded DNA binding protein 4	384	0.71
chr10_85954017_85954268	0.35	CDHR1	cadherin-related family member 1	268	0.89
chr17_26205846_26205997	0.34	RP11-138P22.1		4250	0.18
chr11_71955241_71955392	0.34	PHOX2A	paired-like homeobox 2a	96	0.94
chr2_240196342_240196584	0.34	ENSG00000265215	.	30694	0.15
chr15_79603262_79603413	0.34	TMED3	transmembrane emp24 protein transport domain containing 3	67	0.97
chr20_32856752_32856919	0.34	ASIP	agouti signaling protein	8664	0.15
chr19_12936644_12936812	0.34	CTD-2265O21.3		203	0.82
chr19_6161467_6161654	0.34	ACSBG2	acyl-CoA synthetase bubblegum family member 2	25850	0.13
chr19_18700873_18701059	0.34	C19orf60	chromosome 19 open reading frame 60	554	0.55
chr14_93081555_93081992	0.34	RIN3	Ras and Rab interactor 3	37073	0.2
chr8_144655209_144655539	0.34	MROH6	maestro heat-like repeat family member 6	233	0.51
chr19_47885013_47885403	0.33	MEIS3	Meis homeobox 3	27201	0.12
chr22_20785961_20786186	0.33	SCARF2	scavenger receptor class F, member 2	6039	0.12
chr19_41349423_41349599	0.33	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	6841	0.14
chr19_49713790_49713941	0.33	TRPM4	transient receptor potential cation channel, subfamily M, member 4	126	0.94
chr6_7271411_7271677	0.33	RP11-69L16.4		4720	0.24
chr17_39942887_39943167	0.33	JUP	junction plakoglobin	10	0.96
chr2_121077549_121077700	0.33	INHBB	inhibin, beta B	26095	0.2
chr9_139090141_139090292	0.33	LHX3	LIM homeobox 3	4788	0.21
chr15_45353267_45353418	0.33	RP11-109D20.1		2437	0.16
chr20_60635054_60635205	0.33	ENSG00000265306	.	4729	0.19
chr7_98467875_98468026	0.32	TMEM130	transmembrane protein 130	291	0.88
chr2_131110050_131110232	0.32	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	3439	0.19
chrX_49033046_49033197	0.32	PLP2	proteolipid protein 2 (colonic epithelium-enriched)	4848	0.09
chr19_35466139_35466290	0.32	ZNF792	zinc finger protein 792	11261	0.12
chr7_156800452_156800603	0.32	MNX1	motor neuron and pancreas homeobox 1	1242	0.34
chr9_95788627_95788837	0.32	FGD3	FYVE, RhoGEF and PH domain containing 3	11390	0.19
chr2_192110954_192111105	0.32	MYO1B	myosin IB	20	0.99
chr5_171604379_171604532	0.32	STK10	serine/threonine kinase 10	10935	0.19
chr22_24825444_24825875	0.32	ADORA2A	adenosine A2a receptor	2129	0.31
chrX_49032595_49032858	0.32	PLP2	proteolipid protein 2 (colonic epithelium-enriched)	4453	0.09
chr6_36930970_36931726	0.32	PI16	peptidase inhibitor 16	9139	0.17
chr10_121040558_121040709	0.31	RP11-79M19.2		55061	0.1
chr17_42393670_42393821	0.31	AC003102.3		1062	0.28
chr7_129420448_129420809	0.31	ENSG00000207691	.	5774	0.16
chrX_110253473_110253624	0.31	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	66035	0.14
chr20_3062971_3063207	0.31	AVP	arginine vasopressin	2281	0.19
chr16_75018526_75018758	0.31	WDR59	WD repeat domain 59	404	0.87
chrX_134429664_134429815	0.31	ZNF75D	zinc finger protein 75D	220	0.95
chr14_24033631_24033782	0.31	AP1G2	adaptor-related protein complex 1, gamma 2 subunit	2091	0.17
chr19_3606868_3607019	0.31	TBXA2R	thromboxane A2 receptor	105	0.73
chr9_95715118_95715525	0.31	FGD3	FYVE, RhoGEF and PH domain containing 3	5588	0.23
chr2_71814483_71814634	0.31	DYSF	dysferlin	120726	0.06
chr11_124746668_124746852	0.31	ROBO3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	524	0.64
chr10_6192977_6193257	0.30	ENSG00000263628	.	1042	0.38
chr9_92050627_92050944	0.30	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	593	0.81
chr1_15573599_15573750	0.30	FHAD1	forkhead-associated (FHA) phosphopeptide binding domain 1	94	0.98
chr16_31093201_31093356	0.30	ZNF646	zinc finger protein 646	6055	0.07
chr1_33565215_33565366	0.30	ADC	arginine decarboxylase	17439	0.18
chr8_127570759_127570910	0.29	FAM84B	family with sequence similarity 84, member B	196	0.83
chr16_66262127_66262278	0.29	ENSG00000201999	.	73510	0.11
chr22_38071514_38071665	0.29	LGALS1	lectin, galactoside-binding, soluble, 1	26	0.95
chr19_46144336_46144530	0.29	C19orf83	chromosome 19 open reading frame 83	516	0.5
chr10_134266352_134266533	0.29	C10orf91	chromosome 10 open reading frame 91	7749	0.19
chr6_35703353_35703635	0.29	RP3-510O8.4		1230	0.28
chr1_27463921_27464408	0.29	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	16809	0.19
chr18_74811106_74811283	0.29	MBP	myelin basic protein	6023	0.31
chr19_56879462_56879613	0.29	ZSCAN5A	zinc finger and SCAN domain containing 5A	215	0.85
chr2_242823885_242824036	0.29	AC131097.3		139	0.93
chr12_132111377_132111841	0.29	ENSG00000212154	.	33999	0.2
chr22_27066729_27066953	0.29	CRYBA4	crystallin, beta A4	48913	0.13
chr9_130689855_130690006	0.29	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1	160	0.9
chr7_5635756_5635907	0.29	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	1514	0.35
chr15_89173527_89174002	0.29	ISG20	interferon stimulated exonuclease gene 20kDa	5620	0.16
chr20_44640901_44641241	0.29	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	3524	0.16
chr7_135195139_135195313	0.29	CNOT4	CCR4-NOT transcription complex, subunit 4	351	0.91
chr3_126209757_126209908	0.29	ZXDC	ZXD family zinc finger C	15070	0.15
chr20_44650406_44650557	0.28	RP11-465L10.10		115	0.5
chr17_40822405_40822817	0.28	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	6358	0.09
chr6_80246853_80247004	0.28	LCA5	Leber congenital amaurosis 5	197	0.97
chr3_100429243_100429647	0.28	TFG	TRK-fused gene	631	0.79
chr19_14665471_14665622	0.28	TECR	trans-2,3-enoyl-CoA reductase	7233	0.1
chr1_27852121_27852272	0.28	RP1-159A19.4		120	0.96
chr7_75622709_75623133	0.28	POR	P450 (cytochrome) oxidoreductase	11692	0.16
chr14_91859082_91859233	0.28	CCDC88C	coiled-coil domain containing 88C	24533	0.2
chr3_42740299_42740539	0.28	HHATL	hedgehog acyltransferase-like	1828	0.2
chrX_1653232_1653496	0.28	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	2636	0.31
chrY_1603232_1603496	0.28	NA	NA	> 10⁶	NA
chr7_155331108_155331259	0.28	CNPY1	canopy FGF signaling regulator 1	4626	0.23
chr17_49336576_49336727	0.28	MBTD1	mbt domain containing 1	747	0.52
chr1_153619171_153619411	0.28	CHTOP	chromatin target of PRMT1	8473	0.07
chr5_171881171_171881322	0.28	SH3PXD2B	SH3 and PX domains 2B	116	0.97
chr5_173229911_173230062	0.28	ENSG00000263401	.	72905	0.11
chr9_70489621_70490021	0.28	CBWD5	COBW domain containing 5	286	0.94
chr16_147116_147267	0.28	Z69720.2		6562	0.1
chr11_1890958_1891109	0.28	LSP1	lymphocyte-specific protein 1	161	0.9
chr17_78194041_78194192	0.28	SGSH	N-sulfoglucosamine sulfohydrolase	16	0.59
chr1_175152809_175152966	0.28	KIAA0040	KIAA0040	9003	0.27
chr6_42337436_42337711	0.28	ENSG00000221252	.	42561	0.15
chr3_16365116_16365267	0.27	RP11-415F23.2		9245	0.17
chr15_31125817_31125968	0.27	ENSG00000221379	.	32383	0.14
chr16_19443871_19444022	0.27	TMC5	transmembrane channel-like 5	14928	0.15
chr7_4923362_4923513	0.27	RADIL	Ras association and DIL domains	87	0.97
chr10_61665530_61665681	0.27	CCDC6	coiled-coil domain containing 6	809	0.73
chrX_65242481_65242632	0.27	ENSG00000207939	.	3844	0.24
chr10_75504524_75504675	0.27	SEC24C	SEC24 family member C	441	0.65
chr2_208364611_208364762	0.27	CREB1	cAMP responsive element binding protein 1	29775	0.18
chr11_64067476_64067822	0.27	TEX40	testis expressed 40	214	0.8
chr19_41381342_41381499	0.27	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	7237	0.14
chr15_77302641_77302975	0.27	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	5344	0.22
chr21_47970216_47970537	0.27	ENSG00000272283	.	14667	0.17
chr15_90695555_90695706	0.27	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	8206	0.13
chr10_80814068_80814219	0.27	ZMIZ1-AS1	ZMIZ1 antisense RNA 1	13082	0.24
chr3_194354391_194354771	0.27	TMEM44	transmembrane protein 44	163	0.88
chr5_110848258_110848409	0.27	STARD4	StAR-related lipid transfer (START) domain containing 4	45	0.87
chr8_145555628_145555779	0.26	SCRT1	scratch family zinc finger 1	4240	0.08
chr16_88712969_88713120	0.26	CYBA	cytochrome b-245, alpha polypeptide	189	0.88
chr19_2456239_2456463	0.26	LMNB2	lamin B2	607	0.65
chr16_4303423_4303660	0.26	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)	10197	0.16
chr20_48837037_48837260	0.26	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	29772	0.18
chr7_5609893_5610044	0.26	ACTB	actin, beta	6553	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	0.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.4	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1	0.3	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.3	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.2	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.3	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0008216	spermidine metabolic process(GO:0008216)
0.0	0.3	GO:0021548	pons development(GO:0021548)
0.0	0.1	GO:0052257	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.2	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.2	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.0	GO:0043380	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.5	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.5	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.6	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.2	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.2	GO:0071333	cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.2	GO:1903078	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0070339	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.2	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.2	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.3	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.0	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.2	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.3	GO:0060079	excitatory postsynaptic potential(GO:0060079)
0.0	0.1	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0042754	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0	0.1	GO:0060914	heart formation(GO:0060914)
0.0	0.0	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.1	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0002369	T cell cytokine production(GO:0002369)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.3	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0021913	ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.0	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.2	GO:0045777	positive regulation of blood pressure(GO:0045777)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0015812	gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.2	GO:0001709	cell fate determination(GO:0001709)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.0	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.0	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0006298	mismatch repair(GO:0006298)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0048194	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.4	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.0	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.0	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.6	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.4	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.4	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.2	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.5	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.2	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.3	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.3	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.0	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.0	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.4	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	1.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	PID ARF 3PATHWAY	Arf1 pathway
0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	PID INSULIN PATHWAY	Insulin Pathway
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	PID BCR 5PATHWAY	BCR signaling pathway
0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	PID IL23 PATHWAY	IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.7	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	REACTOME DEFENSINS	Genes involved in Defensins
0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Results for KLF14_SP8

Z-value: 2.03

Motif logo

Transcription factors associated with KLF14_SP8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the KLF14_SP8 motif across conditions

Conditions sorted by the z-value of the KLF14_SP8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: