Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for LEF1

Z-value: 2.73

Motif logo

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Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
ENSG00000138795.5 LEF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
LEF1chr4_109044873_109045024425090.1573480.982.5e-06Click!
LEF1chr4_109029927_109030290573490.1236950.972.1e-05Click!
LEF1chr4_109057827_109057978295550.1880880.963.0e-05Click!
LEF1chr4_109055473_109055665318880.1826640.963.9e-05Click!
LEF1chr4_109027301_109027793599100.1183860.964.2e-05Click!

Activity of the LEF1 motif across conditions

Conditions sorted by the z-value of the LEF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_39163244_39163586 0.98 FYB
FYN binding protein
39714
0.18
chr12_95383197_95383469 0.91 NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
14143
0.23
chr7_37349133_37349657 0.87 ELMO1
engulfment and cell motility 1
32972
0.18
chr19_10254387_10254800 0.76 EIF3G
eukaryotic translation initiation factor 3, subunit G
24015
0.07
chr3_32344273_32344503 0.75 ENSG00000207857
.
43168
0.14
chr1_198503645_198504115 0.69 ATP6V1G3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
5924
0.32
chr13_114912317_114912766 0.69 RASA3
RAS p21 protein activator 3
14455
0.21
chr11_128653079_128653231 0.68 FLI1
Fli-1 proto-oncogene, ETS transcription factor
18470
0.2
chr13_114914753_114915138 0.67 RASA3
RAS p21 protein activator 3
16859
0.2
chr4_109029927_109030290 0.67 LEF1
lymphoid enhancer-binding factor 1
57349
0.12
chr13_52395086_52395622 0.66 RP11-327P2.5

16921
0.18
chr6_2857051_2857287 0.65 ENSG00000266750
.
2828
0.25
chr1_160598519_160598922 0.63 SLAMF1
signaling lymphocytic activation molecule family member 1
18091
0.14
chr20_3134599_3134750 0.62 UBOX5
U-box domain containing 5
5848
0.12
chr17_25545440_25545735 0.62 ENSG00000263583
.
75435
0.11
chr15_70772794_70773262 0.61 UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
221592
0.02
chr12_96501965_96502243 0.60 ENSG00000266889
.
6077
0.22
chr6_112014068_112014237 0.60 FYN
FYN oncogene related to SRC, FGR, YES
27113
0.18
chr6_130543838_130543989 0.59 SAMD3
sterile alpha motif domain containing 3
45
0.99
chr17_46515212_46515468 0.59 SKAP1
src kinase associated phosphoprotein 1
7759
0.15
chr1_121258953_121259201 0.59 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
323140
0.01
chr15_77454937_77455088 0.58 TSPAN3
tetraspanin 3
78686
0.09
chr18_60979198_60979416 0.58 RP11-28F1.2

2008
0.3
chr5_35833459_35833610 0.58 CTD-2113L7.1

6414
0.21
chr6_143229651_143229867 0.58 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
36579
0.2
chr5_175460701_175460852 0.58 THOC3
THO complex 3
907
0.51
chr1_154438581_154439022 0.57 RP11-350G8.9

13687
0.12
chrX_19761943_19762207 0.57 SH3KBP1
SH3-domain kinase binding protein 1
2454
0.43
chr4_109038555_109038892 0.57 LEF1
lymphoid enhancer-binding factor 1
48734
0.14
chr1_186258649_186258839 0.56 PRG4
proteoglycan 4
6661
0.2
chr1_7990434_7990597 0.56 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
4645
0.21
chr2_231322568_231322719 0.56 SP100
SP100 nuclear antigen
4507
0.27
chr18_56809913_56810064 0.55 SEC11C
SEC11 homolog C (S. cerevisiae)
2857
0.35
chr12_69285926_69286077 0.55 ENSG00000252770
.
19700
0.15
chr18_56326833_56326984 0.55 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
11710
0.14
chr1_65343327_65343799 0.54 JAK1
Janus kinase 1
88624
0.08
chr20_49543758_49543983 0.54 ADNP
activity-dependent neuroprotector homeobox
1483
0.3
chr3_118668002_118668153 0.54 IGSF11-AS1
IGSF11 antisense RNA 1
6157
0.29
chr2_32160623_32160774 0.54 ENSG00000221326
.
15680
0.19
chr6_144696611_144696823 0.54 UTRN
utrophin
31480
0.21
chr13_95159605_95159756 0.53 DCT
dopachrome tautomerase
27744
0.19
chr10_11273304_11273484 0.53 RP3-323N1.2

60055
0.12
chr18_60960927_60961165 0.53 RP11-28F1.2

20269
0.17
chr5_169760742_169761397 0.53 KCNIP1
Kv channel interacting protein 1
19422
0.18
chr6_128133123_128133274 0.53 THEMIS
thymocyte selection associated
88905
0.1
chr5_57754783_57754943 0.52 PLK2
polo-like kinase 2
1224
0.53
chr17_74195218_74195369 0.52 RNF157
ring finger protein 157
32130
0.11
chr2_136809392_136809630 0.52 AC093391.2

39476
0.17
chr16_22374784_22374935 0.52 RP11-21M24.3

1583
0.31
chr10_14581358_14581509 0.51 FAM107B
family with sequence similarity 107, member B
6724
0.26
chr1_101706352_101706538 0.51 RP4-575N6.5

2269
0.24
chr13_78274408_78274775 0.51 SLAIN1
SLAIN motif family, member 1
1574
0.38
chr15_38976681_38977159 0.51 C15orf53
chromosome 15 open reading frame 53
11879
0.28
chr2_175353345_175353496 0.51 GPR155
G protein-coupled receptor 155
1598
0.4
chr19_5950706_5950998 0.50 RANBP3
RAN binding protein 3
27238
0.08
chr21_36416088_36416341 0.50 RUNX1
runt-related transcription factor 1
5248
0.35
chr15_58914890_58915041 0.50 ENSG00000239100
.
22531
0.17
chr3_107697956_107698544 0.50 CD47
CD47 molecule
78958
0.11
chr10_126404723_126405025 0.50 FAM53B-AS1
FAM53B antisense RNA 1
12121
0.18
chr17_40636532_40636792 0.50 ENSG00000264314
.
10129
0.09
chr2_43413623_43414100 0.50 ZFP36L2
ZFP36 ring finger protein-like 2
39887
0.17
chrX_123120182_123120333 0.50 STAG2
stromal antigen 2
23237
0.22
chr4_122110306_122110568 0.49 ENSG00000252183
.
3621
0.28
chr2_231361368_231362080 0.49 SP100
SP100 nuclear antigen
7253
0.21
chr1_76760906_76761057 0.49 ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
220577
0.02
chr15_58001915_58002066 0.49 POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
3067
0.36
chr14_61850578_61851088 0.49 PRKCH
protein kinase C, eta
6579
0.26
chr2_101260921_101261203 0.49 ENSG00000265839
.
43734
0.14
chr13_49512520_49512861 0.49 ENSG00000265585
.
8342
0.23
chr14_22995523_22996056 0.49 TRAJ15
T cell receptor alpha joining 15
2791
0.16
chr10_11231925_11232076 0.49 RP3-323N1.2

18661
0.21
chr13_109062811_109063048 0.49 ENSG00000223177
.
109250
0.07
chr2_44901800_44902050 0.49 ENSG00000252896
.
107344
0.07
chr15_52778905_52779098 0.49 MYO5A
myosin VA (heavy chain 12, myoxin)
42037
0.16
chr7_100814110_100814261 0.49 VGF
VGF nerve growth factor inducible
5311
0.1
chr14_98650836_98650996 0.49 ENSG00000222066
.
147171
0.05
chr18_29679004_29679408 0.49 ENSG00000238982
.
4739
0.14
chr1_198617796_198617982 0.49 PTPRC
protein tyrosine phosphatase, receptor type, C
9597
0.24
chr6_160203746_160203924 0.49 ENSG00000207392
.
2422
0.16
chr2_198101522_198101823 0.48 ANKRD44
ankyrin repeat domain 44
38910
0.14
chr6_167536441_167536973 0.48 CCR6
chemokine (C-C motif) receptor 6
448
0.83
chr3_188862026_188862244 0.48 TPRG1
tumor protein p63 regulated 1
27628
0.25
chr5_67555215_67555697 0.48 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
19730
0.25
chr5_55778006_55778314 0.48 CTC-236F12.4
Uncharacterized protein
564
0.79
chr2_106778172_106778934 0.48 UXS1
UDP-glucuronate decarboxylase 1
1472
0.48
chr8_134071429_134072001 0.48 SLA
Src-like-adaptor
888
0.68
chr1_236447358_236447555 0.47 ERO1LB
ERO1-like beta (S. cerevisiae)
2137
0.29
chr2_103035509_103035977 0.47 IL18RAP
interleukin 18 receptor accessory protein
162
0.94
chr6_52849862_52850203 0.47 ENSG00000252106
.
5979
0.14
chr12_6570561_6570923 0.47 VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
9069
0.09
chr6_149815060_149815270 0.47 ZC3H12D
zinc finger CCCH-type containing 12D
8968
0.15
chr15_73032253_73032404 0.47 BBS4
Bardet-Biedl syndrome 4
8305
0.17
chr4_99606743_99606894 0.47 RP11-1299A16.3

26763
0.2
chr3_105501258_105501409 0.47 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
80288
0.12
chr2_24437987_24438211 0.47 AC009228.1

849
0.5
chr1_172612946_172613385 0.46 FASLG
Fas ligand (TNF superfamily, member 6)
14989
0.23
chr14_71113118_71113269 0.46 TTC9
tetratricopeptide repeat domain 9
4689
0.24
chr10_120851648_120851810 0.46 EIF3A
eukaryotic translation initiation factor 3, subunit A
11413
0.13
chr9_4597544_4597807 0.46 SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
25340
0.19
chr21_19186267_19186567 0.46 C21orf91
chromosome 21 open reading frame 91
4919
0.23
chr3_31271817_31272124 0.46 ENSG00000222983
.
1763
0.49
chr10_87373902_87374053 0.45 RP11-93H12.2

8827
0.23
chr10_73491368_73491519 0.45 C10orf105
chromosome 10 open reading frame 105
6138
0.23
chr1_112167121_112167315 0.45 RAP1A
RAP1A, member of RAS oncogene family
4449
0.21
chr13_75891307_75891494 0.45 TBC1D4
TBC1 domain family, member 4
24267
0.22
chr12_105133638_105133797 0.45 ENSG00000222579
.
111885
0.06
chr3_114882840_114883134 0.45 ZBTB20
zinc finger and BTB domain containing 20
16869
0.31
chr2_204585403_204585554 0.45 CD28
CD28 molecule
14062
0.22
chr11_122951924_122952075 0.45 HSPA8
heat shock 70kDa protein 8
18061
0.14
chr2_46578248_46578673 0.45 EPAS1
endothelial PAS domain protein 1
53919
0.14
chr13_99971792_99971943 0.45 GPR183
G protein-coupled receptor 183
12208
0.2
chr9_124115505_124115778 0.45 AL161784.1
Uncharacterized protein
12016
0.14
chr3_187539986_187540311 0.44 BCL6
B-cell CLL/lymphoma 6
76633
0.11
chr1_224567153_224567600 0.44 ENSG00000266618
.
18637
0.14
chr6_109357211_109357383 0.44 ENSG00000199944
.
23520
0.16
chr5_10446969_10447137 0.44 ROPN1L
rhophilin associated tail protein 1-like
5065
0.16
chr11_67111737_67112011 0.44 POLD4
polymerase (DNA-directed), delta 4, accessory subunit
9111
0.09
chr2_191936002_191936213 0.44 ENSG00000231858
.
49855
0.11
chr11_85468020_85468176 0.44 SYTL2
synaptotagmin-like 2
670
0.74
chr14_66313526_66313763 0.44 CTD-2014B16.3
Uncharacterized protein
157597
0.04
chr17_61687614_61687765 0.44 TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I
9458
0.14
chr12_68197431_68197773 0.43 RP11-335O4.3

132903
0.05
chr11_14095486_14095729 0.43 ENSG00000212365
.
60925
0.15
chrX_153357689_153358011 0.43 MECP2
methyl CpG binding protein 2 (Rett syndrome)
4586
0.16
chr14_98689187_98689819 0.43 ENSG00000222066
.
108584
0.07
chr1_169558158_169558702 0.43 F5
coagulation factor V (proaccelerin, labile factor)
2604
0.31
chr6_12126412_12126563 0.43 HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
508
0.88
chr18_29620502_29620880 0.43 ENSG00000265063
.
20261
0.13
chr14_32571246_32571446 0.43 ARHGAP5
Rho GTPase activating protein 5
23909
0.18
chr10_121237439_121237906 0.43 RGS10
regulator of G-protein signaling 10
49317
0.14
chr11_128617499_128618014 0.43 FLI1
Fli-1 proto-oncogene, ETS transcription factor
16929
0.2
chr16_30392632_30392982 0.43 SEPT1
septin 1
945
0.31
chr8_41845965_41846221 0.43 KAT6A
K(lysine) acetyltransferase 6A
30212
0.18
chr2_169307443_169307594 0.43 ENSG00000241074
.
316
0.89
chr22_42683170_42683321 0.42 TCF20
transcription factor 20 (AR1)
56377
0.11
chr3_112408721_112408872 0.42 CCDC80
coiled-coil domain containing 80
48649
0.15
chr6_143210581_143210732 0.42 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
52472
0.16
chr14_50511452_50511646 0.42 ENSG00000201358
.
23737
0.14
chr18_20601406_20601557 0.42 ENSG00000223023
.
3078
0.21
chr5_114858752_114858964 0.42 FEM1C
fem-1 homolog c (C. elegans)
21733
0.2
chr1_117296335_117296486 0.42 CD2
CD2 molecule
597
0.78
chr3_108553144_108553369 0.42 TRAT1
T cell receptor associated transmembrane adaptor 1
11637
0.26
chr1_24851023_24851224 0.42 ENSG00000266551
.
5081
0.18
chr1_208008841_208008992 0.42 ENSG00000203709
.
33048
0.19
chr16_67620539_67620690 0.42 CTCF
CCCTC-binding factor (zinc finger protein)
24304
0.08
chr3_46319179_46319439 0.42 CCR3
chemokine (C-C motif) receptor 3
12690
0.21
chr17_75663314_75663598 0.42 SEPT9
septin 9
185461
0.03
chr16_28504230_28504381 0.41 CLN3
ceroid-lipofuscinosis, neuronal 3
211
0.88
chrX_17877553_17877704 0.41 RAI2
retinoic acid induced 2
1199
0.63
chr15_26092284_26092435 0.41 ENSG00000266517
.
1613
0.38
chr1_153615157_153615308 0.41 CHTOP
chromatin target of PRMT1
4414
0.09
chr10_112689056_112689207 0.41 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
9826
0.14
chr6_163219933_163220084 0.41 PACRG
PARK2 co-regulated
15269
0.28
chr3_33095798_33096165 0.41 GLB1
galactosidase, beta 1
42303
0.12
chr1_100866866_100867158 0.41 ENSG00000216067
.
22681
0.18
chr10_130855671_130855903 0.41 MGMT
O-6-methylguanine-DNA methyltransferase
409661
0.01
chr8_81289205_81289813 0.41 ENSG00000252884
.
28242
0.19
chr8_37131917_37132068 0.41 RP11-150O12.6

242547
0.02
chr2_191874328_191874547 0.41 STAT1
signal transducer and activator of transcription 1, 91kDa
3876
0.21
chr5_39275310_39275719 0.41 FYB
FYN binding protein
884
0.72
chr8_59924673_59924824 0.40 RP11-328K2.1

19251
0.25
chr1_111176210_111176587 0.40 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
2302
0.29
chr4_6697224_6697376 0.40 S100P
S100 calcium binding protein P
2504
0.21
chr8_129556248_129556417 0.40 ENSG00000221351
.
275708
0.01
chr17_34040072_34040441 0.40 RASL10B
RAS-like, family 10, member B
18412
0.11
chr3_71136097_71136325 0.40 FOXP1
forkhead box P1
21293
0.28
chr10_76727829_76728046 0.40 RP11-77G23.5

56072
0.12
chr1_26005320_26005471 0.40 RP1-187B23.1

19793
0.17
chr4_186185134_186185431 0.40 SNX25
sorting nexin 25
54049
0.11
chr15_64152644_64152888 0.40 ENSG00000199156
.
10452
0.21
chr2_30559450_30559652 0.40 ENSG00000221377
.
95763
0.07
chr9_88953538_88953925 0.40 ZCCHC6
zinc finger, CCHC domain containing 6
4307
0.27
chr17_47823245_47823396 0.40 FAM117A
family with sequence similarity 117, member A
18173
0.14
chr17_37916952_37917103 0.40 IKZF3
IKAROS family zinc finger 3 (Aiolos)
17451
0.11
chr9_100666794_100667000 0.40 C9orf156
chromosome 9 open reading frame 156
7856
0.16
chrX_119889254_119889658 0.40 CT47B1
cancer/testis antigen family 47, member B1
120323
0.04
chr18_3059865_3060090 0.40 ENSG00000252353
.
33589
0.13
chr9_92082755_92083098 0.40 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
11879
0.23
chr7_110736643_110736794 0.40 LRRN3
leucine rich repeat neuronal 3
5619
0.27
chr21_35468926_35469077 0.39 SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
23131
0.19
chr9_92133489_92134097 0.39 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
20748
0.2
chr2_106797151_106797302 0.39 AC018878.3

1228
0.54
chr11_36472811_36473244 0.39 RP11-219O3.2

25355
0.17
chr13_52527464_52527703 0.39 ATP7B
ATPase, Cu++ transporting, beta polypeptide
8468
0.22
chr17_66343908_66344364 0.39 ARSG
arylsulfatase G
56477
0.1
chr2_135099020_135099171 0.39 MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
87265
0.1
chr8_8731469_8731701 0.39 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
19570
0.19
chr1_187061554_187061705 0.39 PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
263507
0.02
chr5_131126504_131126655 0.39 FNIP1
folliculin interacting protein 1
6035
0.23
chr2_198057877_198058189 0.39 AC013264.2

4682
0.23
chr11_114001658_114001870 0.39 ENSG00000221112
.
44113
0.16
chr10_17469095_17469250 0.39 ST8SIA6-AS1
ST8SIA6 antisense RNA 1
19146
0.17
chr12_4926448_4926851 0.39 KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
8307
0.2
chr1_206738972_206739123 0.39 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
8554
0.17
chr17_74979048_74979216 0.39 ENSG00000267568
.
13894
0.22
chr6_159486400_159486551 0.39 TAGAP
T-cell activation RhoGTPase activating protein
20291
0.18
chr3_112460889_112461040 0.39 ENSG00000242770
.
60361
0.12
chr4_40245605_40245832 0.39 RHOH
ras homolog family member H
43754
0.15
chr1_6091978_6092246 0.39 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
2231
0.28
chr7_127054523_127055019 0.38 ZNF800
zinc finger protein 800
17207
0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of LEF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 0.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.4 1.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.4 1.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.4 0.4 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.3 1.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3 0.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 1.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 0.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 0.9 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 1.5 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.2 2.3 GO:0043368 positive T cell selection(GO:0043368)
0.2 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.2 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.6 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.2 0.7 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 1.2 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.2 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 1.0 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.7 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0002507 tolerance induction(GO:0002507)
0.1 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.1 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.6 GO:0070670 response to interleukin-4(GO:0070670)
0.1 8.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.8 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.3 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.1 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.1 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.9 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.5 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.4 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.2 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.2 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 0.2 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.9 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.4 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.1 0.3 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.8 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.5 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.1 GO:0002886 regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.1 0.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.2 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.1 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.1 GO:0016556 mRNA modification(GO:0016556)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.1 0.4 GO:1902115 regulation of organelle assembly(GO:1902115)
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 0.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.1 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1 0.3 GO:0016571 histone methylation(GO:0016571)
0.1 0.5 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.3 GO:2000258 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.2 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.1 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.1 0.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.3 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.2 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.1 GO:0032418 lysosome localization(GO:0032418)
0.1 0.4 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.1 0.1 GO:0022616 DNA strand elongation(GO:0022616)
0.1 0.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 0.2 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.1 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0090266 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.3 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.9 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.1 GO:0001821 histamine secretion(GO:0001821)
0.1 0.2 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.1 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.8 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.1 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 2.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.1 GO:0070245 positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.1 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.2 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 0.2 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1 0.2 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.1 0.3 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.2 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0031442 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0060430 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0042321 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0032914 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.2 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.2 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0072075 kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075) kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0052510 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.6 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.8 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0072111 cell proliferation involved in kidney development(GO:0072111)
0.0 0.0 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.0 0.2 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0032769 negative regulation of monooxygenase activity(GO:0032769)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0046479 glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0072273 metanephric nephron morphogenesis(GO:0072273)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.1 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:1902305 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0021702 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar cortex formation(GO:0021697) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.0 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 2.0 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.2 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0036473 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.0 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.7 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.0 GO:0042891 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0042482 positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.0 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.0 GO:0003341 cilium movement(GO:0003341)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457) maintenance of protein localization in organelle(GO:0072595)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.4 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.0 GO:0051324 prophase(GO:0051324)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.1 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.0 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0070193 synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 0.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:0046668 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.2 GO:0002209 behavioral defense response(GO:0002209)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.0 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0032048 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0010535 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.6 GO:0000084 mitotic S phase(GO:0000084)
0.0 0.1 GO:0042596 fear response(GO:0042596)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 1.8 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.7 GO:0097194 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0042044 fluid transport(GO:0042044)
0.0 0.6 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0 0.0 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 1.3 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.7 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.2 GO:0016236 macroautophagy(GO:0016236)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 1.6 GO:0006397 mRNA processing(GO:0006397)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.0 GO:0034443 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0008380 RNA splicing(GO:0008380)
0.0 0.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0030147 obsolete natriuresis(GO:0030147)
0.0 0.1 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.8 GO:0019080 viral gene expression(GO:0019080) viral transcription(GO:0019083)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.0 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0007632 visual behavior(GO:0007632)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.6 GO:0006364 rRNA processing(GO:0006364)
0.0 0.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0002724 regulation of T cell cytokine production(GO:0002724)
0.0 0.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0051350 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0034105 positive regulation of tissue remodeling(GO:0034105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.2 0.7 GO:0043218 compact myelin(GO:0043218)
0.2 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.6 GO:0043209 myelin sheath(GO:0043209)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 2.1 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 2.3 GO:0030175 filopodium(GO:0030175)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0001740 Barr body(GO:0001740)
0.1 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.7 GO:0045120 pronucleus(GO:0045120)
0.1 0.2 GO:0071942 XPC complex(GO:0071942)
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0000346 transcription export complex(GO:0000346)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0035097 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.1 GO:0044462 external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 2.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.1 GO:0097525 spliceosomal snRNP complex(GO:0097525)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0031248 histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0 1.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 2.0 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.9 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 3.7 GO:0005768 endosome(GO:0005768)
0.0 0.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 10.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 0.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 2.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.4 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.7 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.1 GO:0060229 lipase activator activity(GO:0060229)
0.1 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.1 GO:0034452 dynactin binding(GO:0034452)
0.1 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.6 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0048156 tau protein binding(GO:0048156)
0.1 0.1 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 1.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0004396 hexokinase activity(GO:0004396)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.0 GO:0015440 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.8 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 1.0 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.0 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.6 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.8 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.2 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 7.7 GO:0003723 RNA binding(GO:0003723)
0.0 2.4 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.0 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 1.0 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 1.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.4 GO:0060589 nucleoside-triphosphatase regulator activity(GO:0060589)
0.0 0.2 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 3.0 GO:0005525 GTP binding(GO:0005525)
0.0 0.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.0 GO:0031210 phosphatidylcholine binding(GO:0031210)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 2.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 2.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 0.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 4.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.0 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 0.1 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.5 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.7 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.0 REACTOME S PHASE Genes involved in S Phase
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 2.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.0 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis