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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for LEF1

Z-value: 2.73

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Transcription factors associated with LEF1

Gene Symbol	Gene ID	Gene Info
LEF1 Ensembl NCBI GeneCards UniProt	ENSG00000138795.5	lymphoid enhancer binding factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr4_109044873_109045024	LEF1	42509	0.157348	0.98	2.5e-06	Click!
chr4_109029927_109030290	LEF1	57349	0.123695	0.97	2.1e-05	Click!
chr4_109057827_109057978	LEF1	29555	0.188088	0.96	3.0e-05	Click!
chr4_109055473_109055665	LEF1	31888	0.182664	0.96	3.9e-05	Click!
chr4_109027301_109027793	LEF1	59910	0.118386	0.96	4.2e-05	Click!

Activity of the LEF1 motif across conditions

Conditions sorted by the z-value of the LEF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_39163244_39163586	0.98	FYB	FYN binding protein	39714	0.18
chr12_95383197_95383469	0.91	NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	14143	0.23
chr7_37349133_37349657	0.87	ELMO1	engulfment and cell motility 1	32972	0.18
chr19_10254387_10254800	0.76	EIF3G	eukaryotic translation initiation factor 3, subunit G	24015	0.07
chr3_32344273_32344503	0.75	ENSG00000207857	.	43168	0.14
chr1_198503645_198504115	0.69	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	5924	0.32
chr13_114912317_114912766	0.69	RASA3	RAS p21 protein activator 3	14455	0.21
chr11_128653079_128653231	0.68	FLI1	Fli-1 proto-oncogene, ETS transcription factor	18470	0.2
chr13_114914753_114915138	0.67	RASA3	RAS p21 protein activator 3	16859	0.2
chr4_109029927_109030290	0.67	LEF1	lymphoid enhancer-binding factor 1	57349	0.12
chr13_52395086_52395622	0.66	RP11-327P2.5		16921	0.18
chr6_2857051_2857287	0.65	ENSG00000266750	.	2828	0.25
chr1_160598519_160598922	0.63	SLAMF1	signaling lymphocytic activation molecule family member 1	18091	0.14
chr20_3134599_3134750	0.62	UBOX5	U-box domain containing 5	5848	0.12
chr17_25545440_25545735	0.62	ENSG00000263583	.	75435	0.11
chr15_70772794_70773262	0.61	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	221592	0.02
chr12_96501965_96502243	0.60	ENSG00000266889	.	6077	0.22
chr6_112014068_112014237	0.60	FYN	FYN oncogene related to SRC, FGR, YES	27113	0.18
chr6_130543838_130543989	0.59	SAMD3	sterile alpha motif domain containing 3	45	0.99
chr17_46515212_46515468	0.59	SKAP1	src kinase associated phosphoprotein 1	7759	0.15
chr1_121258953_121259201	0.59	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	323140	0.01
chr15_77454937_77455088	0.58	TSPAN3	tetraspanin 3	78686	0.09
chr18_60979198_60979416	0.58	RP11-28F1.2		2008	0.3
chr5_35833459_35833610	0.58	CTD-2113L7.1		6414	0.21
chr6_143229651_143229867	0.58	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	36579	0.2
chr5_175460701_175460852	0.58	THOC3	THO complex 3	907	0.51
chr1_154438581_154439022	0.57	RP11-350G8.9		13687	0.12
chrX_19761943_19762207	0.57	SH3KBP1	SH3-domain kinase binding protein 1	2454	0.43
chr4_109038555_109038892	0.57	LEF1	lymphoid enhancer-binding factor 1	48734	0.14
chr1_186258649_186258839	0.56	PRG4	proteoglycan 4	6661	0.2
chr1_7990434_7990597	0.56	TNFRSF9	tumor necrosis factor receptor superfamily, member 9	4645	0.21
chr2_231322568_231322719	0.56	SP100	SP100 nuclear antigen	4507	0.27
chr18_56809913_56810064	0.55	SEC11C	SEC11 homolog C (S. cerevisiae)	2857	0.35
chr12_69285926_69286077	0.55	ENSG00000252770	.	19700	0.15
chr18_56326833_56326984	0.55	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	11710	0.14
chr1_65343327_65343799	0.54	JAK1	Janus kinase 1	88624	0.08
chr20_49543758_49543983	0.54	ADNP	activity-dependent neuroprotector homeobox	1483	0.3
chr3_118668002_118668153	0.54	IGSF11-AS1	IGSF11 antisense RNA 1	6157	0.29
chr2_32160623_32160774	0.54	ENSG00000221326	.	15680	0.19
chr6_144696611_144696823	0.54	UTRN	utrophin	31480	0.21
chr13_95159605_95159756	0.53	DCT	dopachrome tautomerase	27744	0.19
chr10_11273304_11273484	0.53	RP3-323N1.2		60055	0.12
chr18_60960927_60961165	0.53	RP11-28F1.2		20269	0.17
chr5_169760742_169761397	0.53	KCNIP1	Kv channel interacting protein 1	19422	0.18
chr6_128133123_128133274	0.53	THEMIS	thymocyte selection associated	88905	0.1
chr5_57754783_57754943	0.52	PLK2	polo-like kinase 2	1224	0.53
chr17_74195218_74195369	0.52	RNF157	ring finger protein 157	32130	0.11
chr2_136809392_136809630	0.52	AC093391.2		39476	0.17
chr16_22374784_22374935	0.52	RP11-21M24.3		1583	0.31
chr10_14581358_14581509	0.51	FAM107B	family with sequence similarity 107, member B	6724	0.26
chr1_101706352_101706538	0.51	RP4-575N6.5		2269	0.24
chr13_78274408_78274775	0.51	SLAIN1	SLAIN motif family, member 1	1574	0.38
chr15_38976681_38977159	0.51	C15orf53	chromosome 15 open reading frame 53	11879	0.28
chr2_175353345_175353496	0.51	GPR155	G protein-coupled receptor 155	1598	0.4
chr19_5950706_5950998	0.50	RANBP3	RAN binding protein 3	27238	0.08
chr21_36416088_36416341	0.50	RUNX1	runt-related transcription factor 1	5248	0.35
chr15_58914890_58915041	0.50	ENSG00000239100	.	22531	0.17
chr3_107697956_107698544	0.50	CD47	CD47 molecule	78958	0.11
chr10_126404723_126405025	0.50	FAM53B-AS1	FAM53B antisense RNA 1	12121	0.18
chr17_40636532_40636792	0.50	ENSG00000264314	.	10129	0.09
chr2_43413623_43414100	0.50	ZFP36L2	ZFP36 ring finger protein-like 2	39887	0.17
chrX_123120182_123120333	0.50	STAG2	stromal antigen 2	23237	0.22
chr4_122110306_122110568	0.49	ENSG00000252183	.	3621	0.28
chr2_231361368_231362080	0.49	SP100	SP100 nuclear antigen	7253	0.21
chr1_76760906_76761057	0.49	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	220577	0.02
chr15_58001915_58002066	0.49	POLR2M	polymerase (RNA) II (DNA directed) polypeptide M	3067	0.36
chr14_61850578_61851088	0.49	PRKCH	protein kinase C, eta	6579	0.26
chr2_101260921_101261203	0.49	ENSG00000265839	.	43734	0.14
chr13_49512520_49512861	0.49	ENSG00000265585	.	8342	0.23
chr14_22995523_22996056	0.49	TRAJ15	T cell receptor alpha joining 15	2791	0.16
chr10_11231925_11232076	0.49	RP3-323N1.2		18661	0.21
chr13_109062811_109063048	0.49	ENSG00000223177	.	109250	0.07
chr2_44901800_44902050	0.49	ENSG00000252896	.	107344	0.07
chr15_52778905_52779098	0.49	MYO5A	myosin VA (heavy chain 12, myoxin)	42037	0.16
chr7_100814110_100814261	0.49	VGF	VGF nerve growth factor inducible	5311	0.1
chr14_98650836_98650996	0.49	ENSG00000222066	.	147171	0.05
chr18_29679004_29679408	0.49	ENSG00000238982	.	4739	0.14
chr1_198617796_198617982	0.49	PTPRC	protein tyrosine phosphatase, receptor type, C	9597	0.24
chr6_160203746_160203924	0.49	ENSG00000207392	.	2422	0.16
chr2_198101522_198101823	0.48	ANKRD44	ankyrin repeat domain 44	38910	0.14
chr6_167536441_167536973	0.48	CCR6	chemokine (C-C motif) receptor 6	448	0.83
chr3_188862026_188862244	0.48	TPRG1	tumor protein p63 regulated 1	27628	0.25
chr5_67555215_67555697	0.48	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	19730	0.25
chr5_55778006_55778314	0.48	CTC-236F12.4	Uncharacterized protein	564	0.79
chr2_106778172_106778934	0.48	UXS1	UDP-glucuronate decarboxylase 1	1472	0.48
chr8_134071429_134072001	0.48	SLA	Src-like-adaptor	888	0.68
chr1_236447358_236447555	0.47	ERO1LB	ERO1-like beta (S. cerevisiae)	2137	0.29
chr2_103035509_103035977	0.47	IL18RAP	interleukin 18 receptor accessory protein	162	0.94
chr6_52849862_52850203	0.47	ENSG00000252106	.	5979	0.14
chr12_6570561_6570923	0.47	VAMP1	vesicle-associated membrane protein 1 (synaptobrevin 1)	9069	0.09
chr6_149815060_149815270	0.47	ZC3H12D	zinc finger CCCH-type containing 12D	8968	0.15
chr15_73032253_73032404	0.47	BBS4	Bardet-Biedl syndrome 4	8305	0.17
chr4_99606743_99606894	0.47	RP11-1299A16.3		26763	0.2
chr3_105501258_105501409	0.47	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	80288	0.12
chr2_24437987_24438211	0.47	AC009228.1		849	0.5
chr1_172612946_172613385	0.46	FASLG	Fas ligand (TNF superfamily, member 6)	14989	0.23
chr14_71113118_71113269	0.46	TTC9	tetratricopeptide repeat domain 9	4689	0.24
chr10_120851648_120851810	0.46	EIF3A	eukaryotic translation initiation factor 3, subunit A	11413	0.13
chr9_4597544_4597807	0.46	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	25340	0.19
chr21_19186267_19186567	0.46	C21orf91	chromosome 21 open reading frame 91	4919	0.23
chr3_31271817_31272124	0.46	ENSG00000222983	.	1763	0.49
chr10_87373902_87374053	0.45	RP11-93H12.2		8827	0.23
chr10_73491368_73491519	0.45	C10orf105	chromosome 10 open reading frame 105	6138	0.23
chr1_112167121_112167315	0.45	RAP1A	RAP1A, member of RAS oncogene family	4449	0.21
chr13_75891307_75891494	0.45	TBC1D4	TBC1 domain family, member 4	24267	0.22
chr12_105133638_105133797	0.45	ENSG00000222579	.	111885	0.06
chr3_114882840_114883134	0.45	ZBTB20	zinc finger and BTB domain containing 20	16869	0.31
chr2_204585403_204585554	0.45	CD28	CD28 molecule	14062	0.22
chr11_122951924_122952075	0.45	HSPA8	heat shock 70kDa protein 8	18061	0.14
chr2_46578248_46578673	0.45	EPAS1	endothelial PAS domain protein 1	53919	0.14
chr13_99971792_99971943	0.45	GPR183	G protein-coupled receptor 183	12208	0.2
chr9_124115505_124115778	0.45	AL161784.1	Uncharacterized protein	12016	0.14
chr3_187539986_187540311	0.44	BCL6	B-cell CLL/lymphoma 6	76633	0.11
chr1_224567153_224567600	0.44	ENSG00000266618	.	18637	0.14
chr6_109357211_109357383	0.44	ENSG00000199944	.	23520	0.16
chr5_10446969_10447137	0.44	ROPN1L	rhophilin associated tail protein 1-like	5065	0.16
chr11_67111737_67112011	0.44	POLD4	polymerase (DNA-directed), delta 4, accessory subunit	9111	0.09
chr2_191936002_191936213	0.44	ENSG00000231858	.	49855	0.11
chr11_85468020_85468176	0.44	SYTL2	synaptotagmin-like 2	670	0.74
chr14_66313526_66313763	0.44	CTD-2014B16.3	Uncharacterized protein	157597	0.04
chr17_61687614_61687765	0.44	TACO1	translational activator of mitochondrially encoded cytochrome c oxidase I	9458	0.14
chr12_68197431_68197773	0.43	RP11-335O4.3		132903	0.05
chr11_14095486_14095729	0.43	ENSG00000212365	.	60925	0.15
chrX_153357689_153358011	0.43	MECP2	methyl CpG binding protein 2 (Rett syndrome)	4586	0.16
chr14_98689187_98689819	0.43	ENSG00000222066	.	108584	0.07
chr1_169558158_169558702	0.43	F5	coagulation factor V (proaccelerin, labile factor)	2604	0.31
chr6_12126412_12126563	0.43	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	508	0.88
chr18_29620502_29620880	0.43	ENSG00000265063	.	20261	0.13
chr14_32571246_32571446	0.43	ARHGAP5	Rho GTPase activating protein 5	23909	0.18
chr10_121237439_121237906	0.43	RGS10	regulator of G-protein signaling 10	49317	0.14
chr11_128617499_128618014	0.43	FLI1	Fli-1 proto-oncogene, ETS transcription factor	16929	0.2
chr16_30392632_30392982	0.43	SEPT1	septin 1	945	0.31
chr8_41845965_41846221	0.43	KAT6A	K(lysine) acetyltransferase 6A	30212	0.18
chr2_169307443_169307594	0.43	ENSG00000241074	.	316	0.89
chr22_42683170_42683321	0.42	TCF20	transcription factor 20 (AR1)	56377	0.11
chr3_112408721_112408872	0.42	CCDC80	coiled-coil domain containing 80	48649	0.15
chr6_143210581_143210732	0.42	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	52472	0.16
chr14_50511452_50511646	0.42	ENSG00000201358	.	23737	0.14
chr18_20601406_20601557	0.42	ENSG00000223023	.	3078	0.21
chr5_114858752_114858964	0.42	FEM1C	fem-1 homolog c (C. elegans)	21733	0.2
chr1_117296335_117296486	0.42	CD2	CD2 molecule	597	0.78
chr3_108553144_108553369	0.42	TRAT1	T cell receptor associated transmembrane adaptor 1	11637	0.26
chr1_24851023_24851224	0.42	ENSG00000266551	.	5081	0.18
chr1_208008841_208008992	0.42	ENSG00000203709	.	33048	0.19
chr16_67620539_67620690	0.42	CTCF	CCCTC-binding factor (zinc finger protein)	24304	0.08
chr3_46319179_46319439	0.42	CCR3	chemokine (C-C motif) receptor 3	12690	0.21
chr17_75663314_75663598	0.42	SEPT9	septin 9	185461	0.03
chr16_28504230_28504381	0.41	CLN3	ceroid-lipofuscinosis, neuronal 3	211	0.88
chrX_17877553_17877704	0.41	RAI2	retinoic acid induced 2	1199	0.63
chr15_26092284_26092435	0.41	ENSG00000266517	.	1613	0.38
chr1_153615157_153615308	0.41	CHTOP	chromatin target of PRMT1	4414	0.09
chr10_112689056_112689207	0.41	SHOC2	soc-2 suppressor of clear homolog (C. elegans)	9826	0.14
chr6_163219933_163220084	0.41	PACRG	PARK2 co-regulated	15269	0.28
chr3_33095798_33096165	0.41	GLB1	galactosidase, beta 1	42303	0.12
chr1_100866866_100867158	0.41	ENSG00000216067	.	22681	0.18
chr10_130855671_130855903	0.41	MGMT	O-6-methylguanine-DNA methyltransferase	409661	0.01
chr8_81289205_81289813	0.41	ENSG00000252884	.	28242	0.19
chr8_37131917_37132068	0.41	RP11-150O12.6		242547	0.02
chr2_191874328_191874547	0.41	STAT1	signal transducer and activator of transcription 1, 91kDa	3876	0.21
chr5_39275310_39275719	0.41	FYB	FYN binding protein	884	0.72
chr8_59924673_59924824	0.40	RP11-328K2.1		19251	0.25
chr1_111176210_111176587	0.40	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	2302	0.29
chr4_6697224_6697376	0.40	S100P	S100 calcium binding protein P	2504	0.21
chr8_129556248_129556417	0.40	ENSG00000221351	.	275708	0.01
chr17_34040072_34040441	0.40	RASL10B	RAS-like, family 10, member B	18412	0.11
chr3_71136097_71136325	0.40	FOXP1	forkhead box P1	21293	0.28
chr10_76727829_76728046	0.40	RP11-77G23.5		56072	0.12
chr1_26005320_26005471	0.40	RP1-187B23.1		19793	0.17
chr4_186185134_186185431	0.40	SNX25	sorting nexin 25	54049	0.11
chr15_64152644_64152888	0.40	ENSG00000199156	.	10452	0.21
chr2_30559450_30559652	0.40	ENSG00000221377	.	95763	0.07
chr9_88953538_88953925	0.40	ZCCHC6	zinc finger, CCHC domain containing 6	4307	0.27
chr17_47823245_47823396	0.40	FAM117A	family with sequence similarity 117, member A	18173	0.14
chr17_37916952_37917103	0.40	IKZF3	IKAROS family zinc finger 3 (Aiolos)	17451	0.11
chr9_100666794_100667000	0.40	C9orf156	chromosome 9 open reading frame 156	7856	0.16
chrX_119889254_119889658	0.40	CT47B1	cancer/testis antigen family 47, member B1	120323	0.04
chr18_3059865_3060090	0.40	ENSG00000252353	.	33589	0.13
chr9_92082755_92083098	0.40	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	11879	0.23
chr7_110736643_110736794	0.40	LRRN3	leucine rich repeat neuronal 3	5619	0.27
chr21_35468926_35469077	0.39	SLC5A3	solute carrier family 5 (sodium/myo-inositol cotransporter), member 3	23131	0.19
chr9_92133489_92134097	0.39	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	20748	0.2
chr2_106797151_106797302	0.39	AC018878.3		1228	0.54
chr11_36472811_36473244	0.39	RP11-219O3.2		25355	0.17
chr13_52527464_52527703	0.39	ATP7B	ATPase, Cu++ transporting, beta polypeptide	8468	0.22
chr17_66343908_66344364	0.39	ARSG	arylsulfatase G	56477	0.1
chr2_135099020_135099171	0.39	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	87265	0.1
chr8_8731469_8731701	0.39	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	19570	0.19
chr1_187061554_187061705	0.39	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	263507	0.02
chr5_131126504_131126655	0.39	FNIP1	folliculin interacting protein 1	6035	0.23
chr2_198057877_198058189	0.39	AC013264.2		4682	0.23
chr11_114001658_114001870	0.39	ENSG00000221112	.	44113	0.16
chr10_17469095_17469250	0.39	ST8SIA6-AS1	ST8SIA6 antisense RNA 1	19146	0.17
chr12_4926448_4926851	0.39	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	8307	0.2
chr1_206738972_206739123	0.39	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	8554	0.17
chr17_74979048_74979216	0.39	ENSG00000267568	.	13894	0.22
chr6_159486400_159486551	0.39	TAGAP	T-cell activation RhoGTPase activating protein	20291	0.18
chr3_112460889_112461040	0.39	ENSG00000242770	.	60361	0.12
chr4_40245605_40245832	0.39	RHOH	ras homolog family member H	43754	0.15
chr1_6091978_6092246	0.39	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	2231	0.28
chr7_127054523_127055019	0.38	ZNF800	zinc finger protein 800	17207	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.5	0.5	GO:0002326	B cell lineage commitment(GO:0002326)
0.4	1.2	GO:0010459	negative regulation of heart rate(GO:0010459)
0.4	1.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.4	0.4	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.3	1.3	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.3	0.8	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	0.5	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	1.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.2	1.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.2	0.7	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.9	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	1.5	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.2	2.3	GO:0043368	positive T cell selection(GO:0043368)
0.2	0.6	GO:0048388	endosomal lumen acidification(GO:0048388)
0.2	0.2	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2	0.6	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.2	0.7	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	1.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.2	0.9	GO:0007256	activation of JNKK activity(GO:0007256)
0.2	0.5	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.2	0.4	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2	1.2	GO:0002837	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.2	1.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.2	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	1.0	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.6	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.4	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.4	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	1.1	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.4	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.7	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.7	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1	0.5	GO:0015705	iodide transport(GO:0015705)
0.1	0.5	GO:0002507	tolerance induction(GO:0002507)
0.1	0.4	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.9	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0033622	integrin activation(GO:0033622)
0.1	0.2	GO:0002707	negative regulation of lymphocyte mediated immunity(GO:0002707)
0.1	0.5	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.1	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.6	GO:0070670	response to interleukin-4(GO:0070670)
0.1	8.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.1	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.6	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.4	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.8	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.8	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.3	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.3	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.3	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.2	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.1	0.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.2	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.9	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.5	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.4	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.3	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.2	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.2	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.1	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.9	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.4	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.3	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.3	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.8	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	0.5	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.1	GO:0002886	regulation of myeloid leukocyte mediated immunity(GO:0002886)
0.1	0.2	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.6	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.1	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.2	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.1	0.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.3	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.2	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.1	0.5	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.1	0.1	GO:0016556	mRNA modification(GO:0016556)
0.1	0.4	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.1	0.4	GO:1902115	regulation of organelle assembly(GO:1902115)
0.1	0.3	GO:0010508	positive regulation of autophagy(GO:0010508)
0.1	0.2	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.1	0.4	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.2	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	0.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.1	GO:0002823	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1	0.3	GO:0016571	histone methylation(GO:0016571)
0.1	0.5	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.5	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.2	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1	0.3	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.3	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	0.1	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.1	0.1	GO:0001787	natural killer cell proliferation(GO:0001787)
0.1	0.3	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1	0.3	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.2	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.1	GO:0032418	lysosome localization(GO:0032418)
0.1	0.4	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.1	0.1	GO:0022616	DNA strand elongation(GO:0022616)
0.1	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.1	0.3	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1	0.2	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.1	0.2	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.1	GO:0000303	response to superoxide(GO:0000303)
0.1	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.2	GO:0090266	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.4	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.1	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.3	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.1	0.9	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	0.2	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.1	0.1	GO:0001821	histamine secretion(GO:0001821)
0.1	0.2	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	1.4	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.1	0.3	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.2	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.8	GO:0046834	lipid phosphorylation(GO:0046834)
0.1	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.1	0.2	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1	2.4	GO:0006968	cellular defense response(GO:0006968)
0.1	0.5	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	0.3	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0070245	positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.1	0.4	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.1	0.1	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.1	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.1	0.5	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1	0.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.2	GO:0009301	snRNA transcription(GO:0009301)
0.1	0.5	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.1	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	0.2	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.3	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.5	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.1	0.2	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1	0.2	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.1	0.3	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.2	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.4	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0031442	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.3	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.5	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.5	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.4	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0060430	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0034776	response to histamine(GO:0034776)
0.0	0.1	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.8	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	1.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0032914	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.6	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.6	GO:0014823	response to activity(GO:0014823)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.1	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.2	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.2	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.6	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.3	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.2	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.2	GO:1902807	negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0072075	kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075) kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.2	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.3	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.9	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0052510	modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0	0.1	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.4	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.6	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.6	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.8	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	1.2	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.0	GO:0003309	type B pancreatic cell differentiation(GO:0003309)
0.0	0.2	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.0	0.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0032769	negative regulation of monooxygenase activity(GO:0032769)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.3	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0046479	glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0072273	metanephric nephron morphogenesis(GO:0072273)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.2	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.1	GO:0000216	obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:1902305	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0021702	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar cortex formation(GO:0021697) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.0	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	2.0	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.6	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	1.2	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.0	GO:0048291	isotype switching to IgG isotypes(GO:0048291)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0006833	water transport(GO:0006833)
0.0	0.7	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.0	GO:0042891	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0042482	positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0	0.3	GO:0045446	endothelial cell differentiation(GO:0045446)
0.0	0.0	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.0	GO:0003341	cilium movement(GO:0003341)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.2	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457) maintenance of protein localization in organelle(GO:0072595)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.0	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.4	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0051324	prophase(GO:0051324)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0072071	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.2	GO:0044349	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.8	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.4	GO:0021549	cerebellum development(GO:0021549)
0.0	0.0	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.2	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0090151	establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	0.3	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.0	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.1	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.4	GO:0051693	actin filament capping(GO:0051693)
0.0	0.2	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.2	GO:0002209	behavioral defense response(GO:0002209)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.4	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:0046950	cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.0	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.9	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.0	GO:0010535	regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	1.6	GO:0000084	mitotic S phase(GO:0000084)
0.0	0.1	GO:0042596	fear response(GO:0042596)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0070972	protein localization to endoplasmic reticulum(GO:0070972)
0.0	0.1	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.9	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.1	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.0	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0032392	DNA geometric change(GO:0032392)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	1.8	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.7	GO:0097194	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.4	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0042044	fluid transport(GO:0042044)
0.0	0.6	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.4	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	1.3	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.7	GO:0006413	translational initiation(GO:0006413)
0.0	0.1	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.2	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.0	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	1.6	GO:0006397	mRNA processing(GO:0006397)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.2	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.0	GO:0034443	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.2	GO:0008380	RNA splicing(GO:0008380)
0.0	0.4	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.0	0.9	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0030147	obsolete natriuresis(GO:0030147)
0.0	0.1	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.8	GO:0019080	viral gene expression(GO:0019080) viral transcription(GO:0019083)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0007632	visual behavior(GO:0007632)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.1	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.6	GO:0006364	rRNA processing(GO:0006364)
0.0	0.0	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.0	0.3	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0051350	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0	0.1	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.1	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.0	GO:0034105	positive regulation of tissue remodeling(GO:0034105)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.3	0.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	0.3	GO:0031932	TORC2 complex(GO:0031932)
0.2	0.7	GO:0043218	compact myelin(GO:0043218)
0.2	0.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	1.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	1.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.6	GO:0070695	FHF complex(GO:0070695)
0.1	1.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	1.2	GO:0001772	immunological synapse(GO:0001772)
0.1	0.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	1.0	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.3	GO:0072487	MSL complex(GO:0072487)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.4	GO:0005827	polar microtubule(GO:0005827)
0.1	0.2	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.4	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	1.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.6	GO:0043209	myelin sheath(GO:0043209)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.7	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	2.1	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.1	2.3	GO:0030175	filopodium(GO:0030175)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.3	GO:0001740	Barr body(GO:0001740)
0.1	0.9	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	0.5	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.7	GO:0045120	pronucleus(GO:0045120)
0.1	0.2	GO:0071942	XPC complex(GO:0071942)
0.1	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1	0.6	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.4	GO:0000346	transcription export complex(GO:0000346)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	1.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	2.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.8	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.3	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.8	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.4	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.8	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	1.9	GO:0016605	PML body(GO:0016605)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.4	GO:0008278	cohesin complex(GO:0008278)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0	1.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.2	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.6	GO:0005776	autophagosome(GO:0005776)
0.0	0.3	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.4	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.2	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0	0.1	GO:0044462	external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	2.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.3	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.4	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.4	GO:0031248	histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.0	1.5	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.6	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.8	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	2.0	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.4	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.9	GO:0000502	proteasome complex(GO:0000502)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.1	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.4	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	1.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.4	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.0	GO:0031045	dense core granule(GO:0031045)
0.0	0.4	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	3.7	GO:0005768	endosome(GO:0005768)
0.0	0.8	GO:0005681	spliceosomal complex(GO:0005681)
0.0	10.1	GO:0005730	nucleolus(GO:0005730)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.0	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3	0.9	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	0.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	2.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	0.9	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	0.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	1.0	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	1.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	0.8	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	0.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.2	0.5	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.2	1.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.8	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.1	GO:0042054	histone methyltransferase activity(GO:0042054)
0.1	0.4	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.4	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.4	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.5	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.8	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.4	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.5	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.8	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.8	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.6	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.3	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.7	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	1.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.7	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	1.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.8	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.6	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	1.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	3.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.3	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	0.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.2	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.1	GO:0060229	lipase activator activity(GO:0060229)
0.1	0.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.1	GO:0034452	dynactin binding(GO:0034452)
0.1	1.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.3	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.3	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.5	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.4	GO:0070513	death domain binding(GO:0070513)
0.1	0.3	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	1.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	1.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.9	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.5	GO:0030332	cyclin binding(GO:0030332)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.3	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.6	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	0.3	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	1.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.6	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	1.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0048156	tau protein binding(GO:0048156)
0.1	0.1	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1	0.3	GO:0031013	troponin I binding(GO:0031013)
0.1	0.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	2.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	1.0	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.8	GO:0043621	protein self-association(GO:0043621)
0.0	1.5	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	2.4	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.6	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.4	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.5	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0004396	hexokinase activity(GO:0004396)
0.0	2.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	1.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	1.0	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.7	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.6	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.9	GO:0003823	antigen binding(GO:0003823)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.7	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0015440	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.6	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.8	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.8	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.2	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	1.0	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	1.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.4	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.2	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.6	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.6	GO:0051087	chaperone binding(GO:0051087)
0.0	0.0	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.5	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.5	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.7	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.4	GO:0019843	rRNA binding(GO:0019843)
0.0	0.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.5	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.3	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.6	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.7	GO:0003954	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.8	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.0	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	1.2	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.0	0.2	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	7.7	GO:0003723	RNA binding(GO:0003723)
0.0	2.4	GO:0016563	obsolete transcription activator activity(GO:0016563)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.3	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	1.0	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0015250	water channel activity(GO:0015250)
0.0	1.1	GO:0003682	chromatin binding(GO:0003682)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	2.4	GO:0060589	nucleoside-triphosphatase regulator activity(GO:0060589)
0.0	0.2	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	3.0	GO:0005525	GTP binding(GO:0005525)
0.0	0.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.0	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.4	GO:0015370	solute:sodium symporter activity(GO:0015370)
0.0	0.0	GO:0031210	phosphatidylcholine binding(GO:0031210)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	13.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	3.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	1.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	1.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	2.0	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	1.8	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.7	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	1.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.5	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	1.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.9	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.4	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID E2F PATHWAY	E2F transcription factor network
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	2.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	2.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	0.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	4.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	2.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.0	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.1	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	0.5	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	0.9	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	0.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	2.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.7	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	1.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	1.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	1.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	2.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	2.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.3	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.5	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.8	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	1.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis

Results for LEF1

Z-value: 2.73

Motif logo

Transcription factors associated with LEF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the LEF1 motif across conditions

Conditions sorted by the z-value of the LEF1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: