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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for LHX3

Z-value: 1.16

Motif logo

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
LHX3
ENSG00000107187.11 LIM homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_139098395_139098546LHX315150.3856430.432.5e-01Click!
chr9_139090141_139090292LHX347880.206786-0.383.2e-01Click!
chr9_139084589_139084740LHX3103400.182530-0.373.3e-01Click!
chr9_139081692_139081843LHX3132370.1775420.333.8e-01Click!
chr9_139085334_139085485LHX395950.184074-0.294.5e-01Click!

Activity of the LHX3 motif across conditions

Conditions sorted by the z-value of the LHX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_177651530_177651798 0.83 ENSG00000199858
 .
 73903
 0.13
chr2_161232105_161232912 0.64 ENSG00000252465
 .
 20971
 0.19
chr1_109912007_109912390 0.61 SORT1
 sortilin 1
 23781
 0.14
chr1_67397953_67399117 0.61 MIER1
 mesoderm induction early response 1, transcriptional regulator
 2609
 0.29
chr3_182992678_182993398 0.61 B3GNT5
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
 9906
 0.2
chr7_40621099_40621486 0.58 AC004988.1
34765
 0.24
chr2_193011022_193011173 0.57 TMEFF2
 transmembrane protein with EGF-like and two follistatin-like domains 2
 48153
 0.19
chr9_93557837_93558119 0.54 SYK
 spleen tyrosine kinase
 6091
 0.34
chr6_144587139_144587431 0.54 UTRN
 utrophin
 19552
 0.24
chr4_53966535_53966686 0.54 RP11-752D24.2
154754
 0.04
chr9_90215657_90216062 0.53 DAPK1-IT1
 DAPK1 intronic transcript 1 (non-protein coding)
 47490
 0.16
chr2_153277819_153278036 0.52 FMNL2
 formin-like 2
 86176
 0.1
chr8_108506998_108507182 0.51 ANGPT1
 angiopoietin 1
 133
 0.98
chr7_81303437_81303728 0.51 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
 88730
 0.1
chr9_79065617_79065768 0.51 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
 8376
 0.27
chr22_33108393_33108637 0.51 LL22NC01-116C6.1
70648
 0.1
chr7_95239146_95239504 0.49 AC002451.3
217
 0.94
chr7_102532081_102532232 0.49 LRRC17
 leucine rich repeat containing 17
 21282
 0.16
chr1_222341096_222341247 0.49 ENSG00000212094
 .
 154739
 0.04
chr11_111848937_111849153 0.49 DIXDC1
 DIX domain containing 1
 1012
 0.41
chr6_12266277_12266506 0.49 EDN1
 endothelin 1
 24205
 0.26
chr12_81256633_81256894 0.48 LIN7A
 lin-7 homolog A (C. elegans)
 26364
 0.17
chr10_31053149_31053377 0.48 SVILP1
 supervillin pseudogene 1
 68413
 0.11
chr5_158127271_158127455 0.47 CTD-2363C16.1
282651
 0.01
chr15_59641636_59642058 0.47 ENSG00000199512
 .
 8231
 0.13
chr12_90127026_90127233 0.47 ENSG00000252207
 .
 6416
 0.21
chr20_4046539_4046763 0.46 RP11-352D3.2
 Uncharacterized protein
 9161
 0.22
chr6_114196551_114196945 0.44 MARCKS
 myristoylated alanine-rich protein kinase C substrate
 18207
 0.17
chr6_17933009_17933323 0.44 KIF13A
 kinesin family member 13A
 54528
 0.15
chr11_122002800_122002951 0.43 ENSG00000198975
 .
 14426
 0.14
chr12_27430347_27430721 0.42 STK38L
 serine/threonine kinase 38 like
 16027
 0.23
chr3_55558379_55558651 0.42 WNT5A
 wingless-type MMTV integration site family, member 5A
 34542
 0.2
chr4_47215322_47215473 0.42 ENSG00000238301
 .
 92657
 0.09
chr6_52425530_52425681 0.42 TRAM2
 translocation associated membrane protein 2
 16108
 0.24
chr3_149058191_149058568 0.42 TM4SF18
 transmembrane 4 L six family member 18
 6178
 0.2
chr10_90411662_90411938 0.41 LIPF
 lipase, gastric
 12398
 0.19
chr14_69555636_69555913 0.41 ENSG00000206768
 .
 54896
 0.12
chr2_100218822_100218973 0.41 AFF3
 AF4/FMR2 family, member 3
 24065
 0.23
chr1_172248149_172248300 0.41 ENSG00000252354
 .
 69059
 0.1
chr4_141866091_141866242 0.41 RNF150
 ring finger protein 150
 52024
 0.17
chr5_14399490_14399641 0.41 TRIO
 trio Rho guanine nucleotide exchange factor
 88992
 0.1
chr18_10142397_10142548 0.41 ENSG00000263630
 .
 137278
 0.05
chr4_186196562_186196713 0.40 SNX25
 sorting nexin 25
 65404
 0.09
chr20_50543676_50543832 0.40 ENSG00000263659
 .
 13618
 0.19
chr8_108325074_108325225 0.40 ANGPT1
 angiopoietin 1
 23601
 0.25
chr3_125019965_125020116 0.40 SLC12A8
 solute carrier family 12, member 8
 22019
 0.2
chr4_24553435_24554115 0.39 ENSG00000243005
 .
 11309
 0.21
chr2_192121899_192122050 0.39 MYO1B
 myosin IB
 5751
 0.29
chr3_154604594_154604879 0.39 MME
 membrane metallo-endopeptidase
 137177
 0.05
chr3_136505593_136506225 0.39 SLC35G2
 solute carrier family 35, member G2
 31952
 0.12
chr2_27905704_27905855 0.39 SUPT7L
 suppressor of Ty 7 (S. cerevisiae)-like
 19103
 0.11
chr3_12235410_12235692 0.39 TIMP4
 TIMP metallopeptidase inhibitor 4
 34700
 0.2
chr4_38986506_38986933 0.39 TMEM156
 transmembrane protein 156
 47322
 0.13
chr12_65674928_65675079 0.39 RP11-305O6.3
434
 0.84
chr3_60921706_60921857 0.39 ENSG00000212211
 .
 79504
 0.12
chr8_58980536_58980687 0.39 FAM110B
 family with sequence similarity 110, member B
 73498
 0.13
chr10_93221945_93222246 0.38 HECTD2
 HECT domain containing E3 ubiquitin protein ligase 2
 198
 0.97
chr1_44966238_44966535 0.38 ENSG00000263381
 .
 44779
 0.13
chr7_137276747_137277035 0.38 PTN
 pleiotrophin
 248280
 0.02
chr7_42233492_42233928 0.38 GLI3
 GLI family zinc finger 3
 33610
 0.25
chr6_3140070_3140221 0.38 BPHL
 biphenyl hydrolase-like (serine hydrolase)
 514
 0.72
chr5_142253906_142254057 0.38 ARHGAP26-AS1
 ARHGAP26 antisense RNA 1
 5494
 0.28
chr11_3980211_3980997 0.38 STIM1
 stromal interaction molecule 1
 12031
 0.18
chrX_134122511_134122662 0.38 SMIM10
 small integral membrane protein 10
 2382
 0.26
chr1_87801300_87801913 0.38 LMO4
 LIM domain only 4
 4255
 0.35
chr6_140892392_140892543 0.38 ENSG00000221336
 .
 89383
 0.1
chr1_95009721_95009872 0.37 F3
 coagulation factor III (thromboplastin, tissue factor)
 2440
 0.41
chr9_130302299_130302610 0.37 FAM129B
 family with sequence similarity 129, member B
 28913
 0.13
chr2_46325558_46325709 0.37 AC017006.2
19666
 0.24
chr9_14251921_14252072 0.37 NFIB
 nuclear factor I/B
 56016
 0.15
chr4_86713976_86714229 0.37 ARHGAP24
 Rho GTPase activating protein 24
 14243
 0.26
chr13_33766329_33766480 0.37 STARD13
 StAR-related lipid transfer (START) domain containing 13
 6188
 0.24
chr6_39772853_39773004 0.37 DAAM2
 dishevelled associated activator of morphogenesis 2
 12134
 0.26
chr16_53809610_53810340 0.37 FTO
 fat mass and obesity associated
 71881
 0.11
chr6_56591218_56591369 0.37 DST
 dystonin
 59384
 0.15
chr6_36403738_36403889 0.36 KCTD20
 potassium channel tetramerization domain containing 20
 6731
 0.14
chr4_125335710_125335861 0.36 ANKRD50
 ankyrin repeat domain 50
 298102
 0.01
chr1_55699646_55699797 0.36 ENSG00000265822
 .
 8407
 0.23
chr4_2869241_2869562 0.36 ADD1
 adducin 1 (alpha)
 8222
 0.19
chr1_152022964_152023546 0.36 S100A11
 S100 calcium binding protein A11
 13744
 0.14
chr3_99500056_99500207 0.36 CMSS1
 cms1 ribosomal small subunit homolog (yeast)
 36547
 0.18
chr2_153441109_153441260 0.36 FMNL2
 formin-like 2
 34908
 0.22
chr8_80274236_80274387 0.35 STMN2
 stathmin-like 2
 248738
 0.02
chr7_82224652_82224988 0.35 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 151706
 0.05
chr3_152745972_152746123 0.35 RP11-529G21.2
133517
 0.05
chr8_128937773_128937924 0.35 TMEM75
 transmembrane protein 75
 22743
 0.19
chr16_69255951_69256102 0.35 RP11-70O5.2
18426
 0.12
chr4_111029289_111029440 0.35 ENSG00000263940
 .
 9528
 0.26
chr10_59804431_59804582 0.35 ENSG00000238970
 .
 194015
 0.03
chr3_188995375_188995558 0.35 TPRG1-AS2
 TPRG1 antisense RNA 2
 37083
 0.21
chr5_167097874_167098025 0.35 CTB-78F1.1
10463
 0.25
chr13_41627976_41628416 0.35 WBP4
 WW domain binding protein 4
 7214
 0.17
chr5_52627031_52627182 0.34 FST
 follistatin
 149133
 0.04
chr17_35567851_35568148 0.34 ACACA
 acetyl-CoA carboxylase alpha
 5273
 0.28
chr9_91346743_91346894 0.34 ENSG00000265873
 .
 14002
 0.29
chr12_27779794_27779945 0.34 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 27588
 0.17
chr10_16952291_16952577 0.34 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 73760
 0.11
chr17_61351351_61351502 0.34 RP11-269G24.2
39456
 0.15
chr10_95235571_95235788 0.34 MYOF
 myoferlin
 6272
 0.2
chr3_24407013_24407164 0.34 THRB-IT1
 THRB intronic transcript 1 (non-protein coding)
 93837
 0.08
chr3_188560859_188561010 0.34 TPRG1
 tumor protein p63 regulated 1
 104069
 0.08
chr7_36487948_36488099 0.34 AC006960.7
14609
 0.19
chr4_178156273_178156424 0.34 RP11-487E13.1
 Uncharacterized protein
 13579
 0.23
chr12_8309941_8310303 0.34 ZNF705A
 zinc finger protein 705A
 492
 0.74
chr13_52928121_52928272 0.34 ENSG00000199605
 .
 45943
 0.13
chr10_54079967_54080118 0.34 DKK1
 dickkopf WNT signaling pathway inhibitor 1
 5986
 0.26
chr2_216529775_216530114 0.34 ENSG00000212055
 .
 213698
 0.02
chr2_145135578_145135895 0.34 GTDC1
 glycosyltransferase-like domain containing 1
 45653
 0.17
chr14_52122560_52122711 0.34 FRMD6
 FERM domain containing 6
 3937
 0.24
chr2_118804547_118804712 0.34 ENSG00000243510
 .
 30671
 0.13
chr1_183776609_183776992 0.34 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
 2510
 0.36
chr1_178143791_178143942 0.34 RASAL2
 RAS protein activator like 2
 80590
 0.11
chr8_32432955_32433282 0.33 NRG1
 neuregulin 1
 26873
 0.26
chr2_55328902_55329053 0.33 ENSG00000266376
 .
 6869
 0.2
chr13_27159400_27159551 0.33 WASF3
 WAS protein family, member 3
 27588
 0.22
chr3_110132390_110132541 0.33 ENSG00000221206
 .
 138347
 0.05
chr12_124515572_124515723 0.33 ZNF664
 zinc finger protein 664
 57805
 0.07
chr3_98701653_98701804 0.33 ENSG00000207331
 .
 74425
 0.1
chr2_200907594_200907745 0.33 C2orf47
 chromosome 2 open reading frame 47
 87125
 0.08
chr6_147234613_147234825 0.33 STXBP5-AS1
 STXBP5 antisense RNA 1
 1977
 0.49
chr6_126268678_126268829 0.33 HINT3
 histidine triad nucleotide binding protein 3
 9174
 0.18
chr13_24462234_24462908 0.33 C1QTNF9B-AS1
 C1QTNF9B antisense RNA 1
 457
 0.68
chr8_59745127_59745278 0.33 ENSG00000201231
 .
 18091
 0.27
chr2_208123731_208123882 0.33 AC007879.5
4830
 0.24
chr8_57806614_57806867 0.33 ENSG00000206975
 .
 22903
 0.26
chr5_124748352_124748503 0.33 ENSG00000222107
 .
 61603
 0.16
chr11_113981742_113981893 0.32 ENSG00000221112
 .
 24166
 0.2
chr3_159542327_159542478 0.32 ENSG00000264146
 .
 1918
 0.3
chr2_114040706_114040961 0.32 PAX8
 paired box 8
 4306
 0.2
chr15_49336349_49337349 0.32 SECISBP2L
 SECIS binding protein 2-like
 1781
 0.28
chr6_158460883_158461210 0.32 SYNJ2
 synaptojanin 2
 22549
 0.18
chr12_18498312_18498592 0.32 PIK3C2G
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
 63474
 0.15
chr8_93978348_93978807 0.32 TRIQK
 triple QxxK/R motif containing
 204
 0.96
chr5_9888608_9888759 0.32 ENSG00000222054
 .
 127664
 0.05
chr8_96574856_96575007 0.32 ENSG00000202112
 .
 36411
 0.22
chr4_38771269_38771420 0.32 TLR10
 toll-like receptor 10
 6473
 0.17
chr17_20092898_20093141 0.32 SPECC1
 sperm antigen with calponin homology and coiled-coil domains 1
 15830
 0.22
chr19_8605989_8606140 0.31 ENSG00000265528
 .
 5679
 0.12
chr10_78157189_78157340 0.31 RP11-369F10.2
41269
 0.18
chr9_133720557_133720776 0.31 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 10213
 0.21
chr8_25066500_25066825 0.31 DOCK5
 dedicator of cytokinesis 5
 24282
 0.21
chr6_56588753_56588904 0.31 DST
 dystonin
 61849
 0.14
chrX_12229658_12229809 0.31 ENSG00000206795
 .
 62488
 0.12
chr5_16890159_16890310 0.31 MYO10
 myosin X
 26402
 0.18
chr6_114290051_114291212 0.31 RP3-399L15.3
234
 0.87
chr9_3912136_3912287 0.31 GLIS3-AS1
 GLIS3 antisense RNA 1
 13569
 0.25
chr3_69813958_69814283 0.31 MITF
 microphthalmia-associated transcription factor
 1158
 0.56
chr12_52348007_52348213 0.31 ACVR1B
 activin A receptor, type IB
 946
 0.5
chr6_140859760_140859911 0.31 ENSG00000221336
 .
 122015
 0.06
chr3_111521650_111521801 0.31 PHLDB2
 pleckstrin homology-like domain, family B, member 2
 56302
 0.14
chr1_17275864_17276015 0.31 CROCC
 ciliary rootlet coiled-coil, rootletin
 26689
 0.11
chr2_40510156_40510307 0.31 AC007377.1
22084
 0.23
chr17_35851980_35852131 0.30 DUSP14
 dual specificity phosphatase 14
 485
 0.81
chr15_57513605_57513971 0.30 TCF12
 transcription factor 12
 2124
 0.42
chr7_38209227_38209494 0.30 STARD3NL
 STARD3 N-terminal like
 8464
 0.31
chr14_61041455_61041606 0.30 ENSG00000253014
 .
 32255
 0.15
chr2_145779005_145779156 0.30 ENSG00000253036
 .
 313558
 0.01
chr4_57909352_57909761 0.30 ENSG00000251703
 .
 40698
 0.11
chr2_225681896_225682047 0.30 DOCK10
 dedicator of cytokinesis 10
 602
 0.85
chr2_75819618_75819769 0.30 EVA1A
 eva-1 homolog A (C. elegans)
 22845
 0.13
chr4_7881276_7881455 0.30 AFAP1
 actin filament associated protein 1
 7325
 0.25
chr12_120131477_120131628 0.30 RP1-127H14.3
 Uncharacterized protein
 6021
 0.18
chr3_72338599_72338998 0.30 ENSG00000212070
 .
 27219
 0.26
chr15_39636633_39636784 0.30 RP11-624L4.1
70624
 0.12
chr7_92295493_92295644 0.30 ENSG00000206763
 .
 35560
 0.18
chr4_182984434_182984585 0.30 AC108142.1
21728
 0.23
chr6_44414403_44414554 0.30 ENSG00000266619
 .
 11100
 0.18
chr5_52079021_52079172 0.29 ITGA1
 integrin, alpha 1
 4634
 0.21
chr1_101108683_101108834 0.29 VCAM1
 vascular cell adhesion molecule 1
 76540
 0.1
chr1_23610078_23610229 0.29 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
 60602
 0.09
chr4_48942200_48942351 0.29 ENSG00000252913
 .
 7404
 0.21
chr15_70556363_70556608 0.29 ENSG00000200216
 .
 70910
 0.13
chr7_152010807_152011572 0.29 KMT2C
 lysine (K)-specific methyltransferase 2C
 66085
 0.11
chr2_69417973_69418124 0.29 ENSG00000199460
 .
 8039
 0.21
chr2_138722580_138722731 0.29 HNMT
 histamine N-methyltransferase
 612
 0.86
chr1_186426484_186426635 0.29 PDC
 phosducin
 3695
 0.21
chr3_167577259_167577557 0.29 SERPINI1
 serpin peptidase inhibitor, clade I (neuroserpin), member 1
 52382
 0.17
chr8_32573551_32573702 0.29 NRG1
 neuregulin 1
 5645
 0.34
chr9_110573374_110573525 0.29 ENSG00000244104
 .
 746
 0.68
chr7_28002187_28002338 0.29 JAZF1
 JAZF zinc finger 1
 29413
 0.22
chr10_104956679_104957044 0.29 NT5C2
 5'-nucleotidase, cytosolic II
 3805
 0.25
chr4_138229530_138229827 0.29 ENSG00000222526
 .
 80396
 0.12
chrX_39832066_39832217 0.29 BCOR
 BCL6 corepressor
 90049
 0.09
chr12_24383335_24383486 0.29 ENSG00000216192
 .
 18055
 0.3
chr6_128390722_128390873 0.29 PTPRK
 protein tyrosine phosphatase, receptor type, K
 4889
 0.29
chr17_57075608_57075759 0.29 ENSG00000216168
 .
 9368
 0.15
chr9_138861135_138861286 0.29 UBAC1
 UBA domain containing 1
 7984
 0.21
chr9_91389382_91389533 0.29 ENSG00000265873
 .
 28637
 0.25
chr5_163012032_163012183 0.29 MAT2B
 methionine adenosyltransferase II, beta
 79487
 0.09
chr2_69469610_69469761 0.29 ENSG00000199460
 .
 59676
 0.11
chr6_15066355_15066506 0.29 ENSG00000242989
 .
 46769
 0.18
chr15_56617819_56617970 0.28 TEX9
 testis expressed 9
 39731
 0.17
chr12_89698996_89699278 0.28 ENSG00000238302
 .
 23075
 0.22
chr11_75657287_75657506 0.28 ENSG00000223013
 .
 11416
 0.16
chr15_34913517_34913668 0.28 ENSG00000252425
 .
 23833
 0.16
chr2_150601107_150601258 0.28 ENSG00000207270
 .
 133894
 0.05
chr1_88305877_88306028 0.28 ENSG00000199318
 .
 386896
 0.01
chr8_99571908_99572059 0.28 KB-1205A7.2
43498
 0.17
chr1_178313576_178313822 0.28 RASAL2
 RAS protein activator like 2
 3093
 0.37
chr16_66604769_66604920 0.28 CMTM1
 CKLF-like MARVEL transmembrane domain containing 1
 4427
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.2 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.2 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.1 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0046882 regulation of follicle-stimulating hormone secretion(GO:0046880) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0060535 lung growth(GO:0060437) trachea cartilage development(GO:0060534) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0071675 mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.1 GO:0003156 regulation of organ formation(GO:0003156)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0044215 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.7 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.0 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.0 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)