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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for LHX6

Z-value: 1.17

Motif logo

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Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
LHX6
ENSG00000106852.11 LIM homeobox 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_124980013_124980164LHX638870.1774330.781.4e-02Click!
chr9_124976522_124976673LHX63960.814498-0.627.4e-02Click!
chr9_124975632_124975793LHX64600.773363-0.511.6e-01Click!
chr9_124976686_124976837LHX65600.707628-0.472.0e-01Click!
chr9_124990834_124991046LHX61840.927646-0.462.1e-01Click!

Activity of the LHX6 motif across conditions

Conditions sorted by the z-value of the LHX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_71030532_71030802 0.79 FOXP1
 forkhead box P1
 83410
 0.1
chr16_27257033_27257252 0.47 NSMCE1
 non-SMC element 1 homolog (S. cerevisiae)
 12330
 0.16
chr4_187545719_187545870 0.44 FAT1
 FAT atypical cadherin 1
 26616
 0.2
chr17_13268235_13268519 0.42 ENSG00000266115
 .
 135268
 0.05
chr17_26498050_26498459 0.41 PYY2
 peptide YY, 2 (pseudogene)
 56078
 0.09
chr1_85904764_85904915 0.39 ENSG00000199459
 .
 3872
 0.26
chr14_100240950_100241315 0.38 EML1
 echinoderm microtubule associated protein like 1
 1091
 0.59
chr11_14466972_14467123 0.37 ENSG00000251991
 .
 33391
 0.17
chr11_1145070_1145742 0.36 MUC5AC
 mucin 5AC, oligomeric mucus/gel-forming
 6174
 0.2
chr17_66379311_66379462 0.36 ENSG00000207561
 .
 41303
 0.14
chr5_158127271_158127455 0.36 CTD-2363C16.1
282651
 0.01
chr21_38799758_38799909 0.35 DYRK1A
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
 7156
 0.25
chr16_56227570_56227809 0.35 GNAO1
 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
 124
 0.91
chr2_47284202_47284907 0.34 AC073283.7
10407
 0.19
chr12_62931646_62931797 0.33 ENSG00000202034
 .
 7738
 0.19
chr8_38790336_38790830 0.32 PLEKHA2
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
 31721
 0.12
chr1_40887310_40887681 0.32 SMAP2
 small ArfGAP2
 24988
 0.12
chr10_17064484_17064884 0.32 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 38490
 0.2
chr8_121665009_121665299 0.32 RP11-713M15.1
108339
 0.07
chr10_75789745_75789896 0.32 RP11-417O11.5
24925
 0.16
chr5_154034007_154034158 0.31 ENSG00000221552
 .
 31254
 0.14
chr15_56439129_56439280 0.31 RFX7
 regulatory factor X, 7
 42880
 0.17
chr9_81321983_81322311 0.31 PSAT1
 phosphoserine aminotransferase 1
 410088
 0.01
chr9_80524258_80524409 0.31 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 86418
 0.1
chr15_42720226_42720377 0.31 ZNF106
 zinc finger protein 106
 1
 0.87
chr7_20071186_20071471 0.31 AC005062.2
28783
 0.23
chr15_101815840_101816133 0.30 VIMP
 VCP-interacting membrane protein
 1506
 0.33
chr7_75952019_75952170 0.29 HSPB1
 heat shock 27kDa protein 1
 19200
 0.14
chr3_64326242_64326393 0.29 PRICKLE2
 prickle homolog 2 (Drosophila)
 72662
 0.11
chr11_131479604_131479755 0.29 NTM
 neurotrimin
 27774
 0.2
chr11_69264697_69264848 0.29 CCND1
 cyclin D1
 191083
 0.03
chr10_29823814_29823965 0.29 ENSG00000207612
 .
 10137
 0.19
chr3_45102056_45102207 0.28 ENSG00000252410
 .
 26051
 0.16
chr6_148845405_148845556 0.28 ENSG00000223322
 .
 104
 0.98
chr6_91072424_91072575 0.28 ENSG00000266760
 .
 50038
 0.15
chr6_39787204_39787470 0.28 DAAM2
 dishevelled associated activator of morphogenesis 2
 26543
 0.21
chr9_89890769_89890954 0.28 ENSG00000212421
 .
 15496
 0.29
chr5_68662452_68662603 0.28 TAF9
 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
 121
 0.95
chr13_60664906_60665057 0.28 DIAPH3-AS2
 DIAPH3 antisense RNA 2
 53851
 0.12
chr3_120146387_120146538 0.28 FSTL1
 follistatin-like 1
 23376
 0.21
chr9_95007298_95007449 0.27 IARS
 isoleucyl-tRNA synthetase
 10
 0.98
chr20_19478003_19478154 0.27 ENSG00000216017
 .
 92753
 0.08
chr4_86683324_86683672 0.27 ARHGAP24
 Rho GTPase activating protein 24
 16361
 0.24
chr1_53462333_53462484 0.27 SCP2
 sterol carrier protein 2
 18192
 0.14
chr1_67043331_67043482 0.27 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 43441
 0.15
chr3_190436866_190437153 0.27 ENSG00000223117
 .
 77057
 0.11
chr9_80463474_80463724 0.27 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 25684
 0.27
chr3_71450784_71450957 0.27 FOXP1
 forkhead box P1
 96959
 0.08
chr17_59362891_59363042 0.27 RP11-332H18.3
97180
 0.06
chr10_17217462_17217735 0.27 TRDMT1
 tRNA aspartic acid methyltransferase 1
 939
 0.58
chr11_111848937_111849153 0.27 DIXDC1
 DIX domain containing 1
 1012
 0.41
chr8_8388322_8388473 0.26 ENSG00000263616
 .
 51768
 0.15
chr1_193304758_193304909 0.26 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 149049
 0.04
chr20_39722951_39723102 0.26 PLCG1
 phospholipase C, gamma 1
 42574
 0.14
chr12_122412428_122412631 0.26 BCL7A
 B-cell CLL/lymphoma 7A
 44799
 0.12
chr7_141061897_141062048 0.26 RP5-842K16.2
69096
 0.12
chr16_85295971_85296292 0.26 ENSG00000266307
 .
 43800
 0.16
chr15_50392799_50393114 0.26 ATP8B4
 ATPase, class I, type 8B, member 4
 13745
 0.23
chr10_111727206_111727357 0.26 RP11-451M19.3
 Uncharacterized protein
 13632
 0.18
chr2_145270130_145270606 0.26 ZEB2
 zinc finger E-box binding homeobox 2
 4747
 0.27
chr3_59761458_59761609 0.26 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 196050
 0.03
chr11_75794475_75794626 0.26 UVRAG
 UV radiation resistance associated
 32407
 0.17
chr12_116596119_116596329 0.26 ENSG00000207967
 .
 9765
 0.21
chr7_41910301_41910559 0.26 AC005027.3
165497
 0.04
chr3_16225459_16225610 0.26 GALNT15
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
 9318
 0.25
chr1_92311778_92311983 0.26 TGFBR3
 transforming growth factor, beta receptor III
 15270
 0.21
chr3_27208769_27208920 0.26 NEK10
 NIMA-related kinase 10
 49122
 0.17
chr15_50194108_50194259 0.25 ATP8B4
 ATPase, class I, type 8B, member 4
 6107
 0.24
chr1_244276859_244277010 0.25 ENSG00000244066
 .
 9700
 0.24
chr14_73613505_73613656 0.25 PSEN1
 presenilin 1
 620
 0.74
chr17_29542627_29542778 0.25 NF1
 neurofibromin 1
 15148
 0.18
chr1_224564194_224564516 0.25 CNIH4
 cornichon family AMPA receptor auxiliary protein 4
 19760
 0.13
chr5_178703659_178703833 0.25 ADAMTS2
 ADAM metallopeptidase with thrombospondin type 1 motif, 2
 68685
 0.12
chr1_218891512_218891663 0.25 ENSG00000212610
 .
 176346
 0.03
chr14_76326894_76327045 0.25 RP11-270M14.4
12928
 0.25
chr3_171039054_171039205 0.25 TNIK
 TRAF2 and NCK interacting kinase
 95629
 0.08
chr1_168329374_168329525 0.25 ENSG00000207974
 .
 15313
 0.23
chr5_158448429_158448934 0.25 CTD-2363C16.2
35867
 0.17
chr11_16377737_16377888 0.25 SOX6
 SRY (sex determining region Y)-box 6
 14997
 0.3
chr16_68771111_68771428 0.24 CDH1
 cadherin 1, type 1, E-cadherin (epithelial)
 14
 0.97
chr9_107630817_107631231 0.24 RP11-217B7.2
58810
 0.12
chr3_100601860_100602011 0.24 ABI3BP
 ABI family, member 3 (NESH) binding protein
 2487
 0.39
chr12_78797307_78797458 0.24 NAV3
 neuron navigator 3
 204526
 0.03
chr20_42213255_42213406 0.24 IFT52
 intraflagellar transport 52 homolog (Chlamydomonas)
 6241
 0.18
chr4_57908197_57908348 0.24 ENSG00000251703
 .
 39414
 0.11
chr10_44312151_44312815 0.24 ZNF32
 zinc finger protein 32
 168179
 0.03
chr8_130566904_130567142 0.24 ENSG00000266387
 .
 57110
 0.09
chr19_47138317_47138577 0.24 GNG8
 guanine nucleotide binding protein (G protein), gamma 8
 505
 0.62
chr3_183886938_183887238 0.24 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
 5389
 0.11
chr4_16233802_16234018 0.24 TAPT1-AS1
 TAPT1 antisense RNA 1 (head to head)
 5242
 0.23
chr4_157298853_157299004 0.24 ENSG00000221189
 .
 81130
 0.11
chr9_79451688_79451839 0.24 PRUNE2
 prune homolog 2 (Drosophila)
 69238
 0.12
chr6_106350521_106350672 0.24 ENSG00000200198
 .
 1652
 0.53
chr4_119097025_119097176 0.24 ENSG00000269893
 .
 103245
 0.08
chr17_66591627_66592081 0.23 FAM20A
 family with sequence similarity 20, member A
 5676
 0.25
chr9_4927697_4927848 0.23 ENSG00000238362
 .
 40325
 0.13
chr9_88955484_88955635 0.23 ZCCHC6
 zinc finger, CCHC domain containing 6
 2479
 0.34
chr2_180911324_180911475 0.23 CWC22
 CWC22 spliceosome-associated protein homolog (S. cerevisiae)
 39559
 0.21
chr2_36720605_36720756 0.23 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 20153
 0.19
chrX_37702580_37702731 0.23 DYNLT3
 dynein, light chain, Tctex-type 3
 4006
 0.26
chr2_200604102_200604338 0.23 FTCDNL1
 formiminotransferase cyclodeaminase N-terminal like
 111376
 0.07
chr8_121769766_121770271 0.23 RP11-713M15.1
3475
 0.31
chr2_46169357_46169508 0.23 PRKCE
 protein kinase C, epsilon
 58609
 0.15
chr10_81181755_81182122 0.23 ZCCHC24
 zinc finger, CCHC domain containing 24
 22037
 0.18
chr8_119923861_119924012 0.23 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
 40503
 0.18
chr4_89647157_89647308 0.23 FAM13A-AS1
 FAM13A antisense RNA 1
 4366
 0.21
chr12_4929077_4929347 0.23 KCNA6
 potassium voltage-gated channel, shaker-related subfamily, member 6
 10870
 0.2
chr16_25017302_25017551 0.23 ARHGAP17
 Rho GTPase activating protein 17
 9226
 0.27
chr6_44989881_44990300 0.23 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 66843
 0.14
chr5_78052251_78052402 0.23 LHFPL2
 lipoma HMGIC fusion partner-like 2
 107678
 0.07
chr10_49809064_49809215 0.23 ARHGAP22
 Rho GTPase activating protein 22
 3858
 0.26
chr6_34314260_34314411 0.23 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 46116
 0.13
chr1_178102184_178102335 0.22 RASAL2
 RAS protein activator like 2
 38983
 0.22
chr2_158326449_158327167 0.22 CYTIP
 cytohesin 1 interacting protein
 18533
 0.22
chr5_111085283_111085434 0.22 NREP
 neuronal regeneration related protein
 6590
 0.22
chr5_120632218_120632474 0.22 FTMT
 ferritin mitochondrial
 555304
 0.0
chr8_80226395_80226546 0.22 ENSG00000264969
 .
 216872
 0.02
chr12_56917827_56917978 0.22 RBMS2
 RNA binding motif, single stranded interacting protein 2
 2119
 0.23
chr17_2120066_2120283 0.22 AC130689.5
865
 0.42
chr2_100625887_100626113 0.22 AFF3
 AF4/FMR2 family, member 3
 94992
 0.08
chr1_25097273_25097424 0.22 ENSG00000238482
 .
 7122
 0.22
chr6_83664770_83664921 0.22 RP11-445L13__B.3
22525
 0.24
chr1_173822290_173822441 0.22 GAS5-AS1
 GAS5 antisense RNA 1
 10021
 0.1
chr3_105699405_105699556 0.22 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 111084
 0.08
chr15_38437640_38437791 0.22 SPRED1
 sprouty-related, EVH1 domain containing 1
 106812
 0.08
chr2_38054791_38055066 0.22 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 89317
 0.09
chr6_37109268_37109585 0.22 PIM1
 pim-1 oncogene
 28553
 0.16
chr18_12421274_12421492 0.22 SLMO1
 slowmo homolog 1 (Drosophila)
 98
 0.96
chr6_155214377_155214528 0.22 ENSG00000238963
 .
 11839
 0.18
chr6_113886507_113886658 0.22 ENSG00000266650
 .
 37535
 0.19
chr16_72972238_72972389 0.22 ENSG00000221799
 .
 46443
 0.15
chr8_108208326_108208625 0.22 ENSG00000211995
 .
 58251
 0.16
chr17_80250217_80250392 0.22 CSNK1D
 casein kinase 1, delta
 18697
 0.1
chr1_2221391_2222142 0.22 RP4-713A8.1
36366
 0.09
chr2_98546607_98546758 0.22 ENSG00000238719
 .
 17102
 0.21
chr11_33934050_33934291 0.22 LMO2
 LIM domain only 2 (rhombotin-like 1)
 20334
 0.2
chr1_97604243_97604422 0.22 DPYD-AS1
 DPYD antisense RNA 1
 42853
 0.21
chr17_27887330_27887481 0.22 RP11-68I3.2
160
 0.9
chr9_79125250_79125401 0.22 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
 51179
 0.15
chr10_20884985_20885136 0.22 ENSG00000265372
 .
 44161
 0.21
chr8_37640875_37641038 0.21 GPR124
 G protein-coupled receptor 124
 753
 0.58
chr2_44576037_44576404 0.21 PREPL
 prolyl endopeptidase-like
 10668
 0.2
chr9_125766060_125766211 0.21 RABGAP1
 RAB GTPase activating protein 1
 29653
 0.12
chr9_82676338_82676489 0.21 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 354732
 0.01
chr2_235485735_235485886 0.21 ARL4C
 ADP-ribosylation factor-like 4C
 80113
 0.12
chr9_82227138_82227289 0.21 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 38609
 0.24
chr12_66296581_66296811 0.21 RP11-366L20.2
 Uncharacterized protein
 20749
 0.16
chr16_83934521_83934672 0.21 MLYCD
 malonyl-CoA decarboxylase
 1865
 0.31
chr13_33768544_33768695 0.21 STARD13
 StAR-related lipid transfer (START) domain containing 13
 8403
 0.23
chr3_45037433_45037728 0.21 EXOSC7
 exosome component 7
 19858
 0.14
chr9_114749197_114749348 0.21 ENSG00000222356
 .
 9747
 0.2
chr13_28054385_28054536 0.21 ENSG00000252499
 .
 7815
 0.19
chr2_65312285_65312436 0.21 RAB1A
 RAB1A, member RAS oncogene family
 21164
 0.16
chr16_72928505_72928656 0.21 ENSG00000251868
 .
 72689
 0.09
chr19_54657228_54657379 0.21 CNOT3
 CCR4-NOT transcription complex, subunit 3
 158
 0.88
chr17_30586530_30586681 0.21 RHBDL3
 rhomboid, veinlet-like 3 (Drosophila)
 6590
 0.16
chr1_170879044_170879195 0.21 MROH9
 maestro heat-like repeat family member 9
 25493
 0.24
chr13_31255786_31256279 0.21 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 53613
 0.14
chr5_34497593_34497744 0.21 RAI14
 retinoic acid induced 14
 158674
 0.04
chr2_208116387_208116719 0.21 AC007879.5
2423
 0.32
chr11_71778137_71778288 0.21 NUMA1
 nuclear mitotic apparatus protein 1
 2921
 0.12
chr5_125339534_125339685 0.21 ENSG00000265637
 .
 192919
 0.03
chr2_157313118_157313429 0.21 GPD2
 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
 16811
 0.19
chr13_88323755_88324230 0.21 SLITRK5
 SLIT and NTRK-like family, member 5
 878
 0.73
chr17_69498538_69498689 0.21 ENSG00000222563
 .
 191304
 0.03
chr10_115033205_115033385 0.21 ENSG00000238380
 .
 79889
 0.11
chr9_79432035_79432186 0.21 PCA3
 prostate cancer antigen 3 (non-protein coding)
 52758
 0.16
chr15_70620773_70621274 0.21 ENSG00000200216
 .
 135448
 0.05
chr12_26811451_26811602 0.21 RP11-666F17.1
35224
 0.22
chr12_124483374_124483666 0.21 ZNF664
 zinc finger protein 664
 25678
 0.08
chr4_83281916_83282171 0.21 HNRNPD
 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
 1251
 0.46
chr19_19220612_19220870 0.21 TMEM161A
 transmembrane protein 161A
 22469
 0.11
chr4_15435517_15435668 0.21 RP11-665G4.1
6054
 0.18
chr14_103162755_103162994 0.21 ENSG00000202459
 .
 1149
 0.54
chr16_50840051_50840280 0.21 RP11-327F22.4
2916
 0.22
chr4_71533612_71533824 0.21 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
 1026
 0.42
chr7_94035985_94036136 0.21 COL1A2
 collagen, type I, alpha 2
 12187
 0.27
chr9_91752254_91752405 0.21 RP11-82L18.2
27480
 0.2
chr1_213499715_213500068 0.20 RPS6KC1
 ribosomal protein S6 kinase, 52kDa, polypeptide 1
 275287
 0.01
chr3_58030666_58030922 0.20 FLNB
 filamin B, beta
 33262
 0.2
chr1_109261913_109262064 0.20 FNDC7
 fibronectin type III domain containing 7
 3045
 0.21
chr17_8576822_8576973 0.20 MYH10
 myosin, heavy chain 10, non-muscle
 42818
 0.14
chr12_19805873_19806024 0.20 ENSG00000200885
 .
 71421
 0.13
chr15_50156516_50156667 0.20 ATP8B4
 ATPase, class I, type 8B, member 4
 12301
 0.22
chr13_98867933_98868084 0.20 ENSG00000263399
 .
 7230
 0.16
chr5_9363080_9363231 0.20 CTD-2201E9.4
232
 0.95
chr9_77791417_77791568 0.20 ENSG00000200041
 .
 5045
 0.24
chr8_27497354_27497505 0.20 SCARA3
 scavenger receptor class A, member 3
 5731
 0.18
chr17_40511255_40511412 0.20 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
 29099
 0.1
chr10_97579295_97579446 0.20 RP11-429G19.3
13895
 0.21
chr3_193856714_193857102 0.20 HES1
 hes family bHLH transcription factor 1
 2974
 0.25
chr10_17151320_17151471 0.20 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 18441
 0.23
chr10_128259000_128259151 0.20 ENSG00000221717
 .
 13442
 0.26
chr6_126142988_126143327 0.20 NCOA7-AS1
 NCOA7 antisense RNA 1
 3153
 0.24
chr5_77796656_77796807 0.20 LHFPL2
 lipoma HMGIC fusion partner-like 2
 48243
 0.18
chr7_2197941_2198092 0.20 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 48780
 0.15
chr11_8091043_8091194 0.20 RP11-236J17.5
9533
 0.15
chr1_198573317_198573468 0.20 PTPRC
 protein tyrosine phosphatase, receptor type, C
 34409
 0.19
chr10_80517839_80518027 0.20 ENSG00000223243
 .
 7574
 0.33
chr18_56031230_56031381 0.20 RP11-845C23.2
7493
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.2 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.2 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0071221 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.4 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.4 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004556 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.0 REACTOME PI 3K CASCADE Genes involved in PI-3K cascade
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling