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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for LHX6

Z-value: 1.17

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Transcription factors associated with LHX6

Gene Symbol	Gene ID	Gene Info
LHX6 Ensembl NCBI GeneCards UniProt	ENSG00000106852.11	LHX6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
LHX6	chr9_124980013_124980164	3887	0.177433	0.78	1.4e-02	Click!
LHX6	chr9_124976522_124976673	396	0.814498	-0.62	7.4e-02	Click!
LHX6	chr9_124975632_124975793	460	0.773363	-0.51	1.6e-01	Click!
LHX6	chr9_124976686_124976837	560	0.707628	-0.47	2.0e-01	Click!
LHX6	chr9_124990834_124991046	184	0.927646	-0.46	2.1e-01	Click!

Activity of the LHX6 motif across conditions

Conditions sorted by the z-value of the LHX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_71030532_71030802	0.79	FOXP1	forkhead box P1	83410	0.1
chr16_27257033_27257252	0.47	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	12330	0.16
chr4_187545719_187545870	0.44	FAT1	FAT atypical cadherin 1	26616	0.2
chr17_13268235_13268519	0.42	ENSG00000266115	.	135268	0.05
chr17_26498050_26498459	0.41	PYY2	peptide YY, 2 (pseudogene)	56078	0.09
chr1_85904764_85904915	0.39	ENSG00000199459	.	3872	0.26
chr14_100240950_100241315	0.38	EML1	echinoderm microtubule associated protein like 1	1091	0.59
chr11_14466972_14467123	0.37	ENSG00000251991	.	33391	0.17
chr11_1145070_1145742	0.36	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	6174	0.2
chr17_66379311_66379462	0.36	ENSG00000207561	.	41303	0.14
chr5_158127271_158127455	0.36	CTD-2363C16.1		282651	0.01
chr21_38799758_38799909	0.35	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	7156	0.25
chr16_56227570_56227809	0.35	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	124	0.91
chr2_47284202_47284907	0.34	AC073283.7		10407	0.19
chr12_62931646_62931797	0.33	ENSG00000202034	.	7738	0.19
chr8_38790336_38790830	0.32	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	31721	0.12
chr1_40887310_40887681	0.32	SMAP2	small ArfGAP2	24988	0.12
chr10_17064484_17064884	0.32	CUBN	cubilin (intrinsic factor-cobalamin receptor)	38490	0.2
chr8_121665009_121665299	0.32	RP11-713M15.1		108339	0.07
chr10_75789745_75789896	0.32	RP11-417O11.5		24925	0.16
chr5_154034007_154034158	0.31	ENSG00000221552	.	31254	0.14
chr15_56439129_56439280	0.31	RFX7	regulatory factor X, 7	42880	0.17
chr9_81321983_81322311	0.31	PSAT1	phosphoserine aminotransferase 1	410088	0.01
chr9_80524258_80524409	0.31	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	86418	0.1
chr15_42720226_42720377	0.31	ZNF106	zinc finger protein 106	1	0.87
chr7_20071186_20071471	0.31	AC005062.2		28783	0.23
chr15_101815840_101816133	0.30	VIMP	VCP-interacting membrane protein	1506	0.33
chr7_75952019_75952170	0.29	HSPB1	heat shock 27kDa protein 1	19200	0.14
chr3_64326242_64326393	0.29	PRICKLE2	prickle homolog 2 (Drosophila)	72662	0.11
chr11_131479604_131479755	0.29	NTM	neurotrimin	27774	0.2
chr11_69264697_69264848	0.29	CCND1	cyclin D1	191083	0.03
chr10_29823814_29823965	0.29	ENSG00000207612	.	10137	0.19
chr3_45102056_45102207	0.28	ENSG00000252410	.	26051	0.16
chr6_148845405_148845556	0.28	ENSG00000223322	.	104	0.98
chr6_91072424_91072575	0.28	ENSG00000266760	.	50038	0.15
chr6_39787204_39787470	0.28	DAAM2	dishevelled associated activator of morphogenesis 2	26543	0.21
chr9_89890769_89890954	0.28	ENSG00000212421	.	15496	0.29
chr5_68662452_68662603	0.28	TAF9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	121	0.95
chr13_60664906_60665057	0.28	DIAPH3-AS2	DIAPH3 antisense RNA 2	53851	0.12
chr3_120146387_120146538	0.28	FSTL1	follistatin-like 1	23376	0.21
chr9_95007298_95007449	0.27	IARS	isoleucyl-tRNA synthetase	10	0.98
chr20_19478003_19478154	0.27	ENSG00000216017	.	92753	0.08
chr4_86683324_86683672	0.27	ARHGAP24	Rho GTPase activating protein 24	16361	0.24
chr1_53462333_53462484	0.27	SCP2	sterol carrier protein 2	18192	0.14
chr1_67043331_67043482	0.27	SGIP1	SH3-domain GRB2-like (endophilin) interacting protein 1	43441	0.15
chr3_190436866_190437153	0.27	ENSG00000223117	.	77057	0.11
chr9_80463474_80463724	0.27	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	25684	0.27
chr3_71450784_71450957	0.27	FOXP1	forkhead box P1	96959	0.08
chr17_59362891_59363042	0.27	RP11-332H18.3		97180	0.06
chr10_17217462_17217735	0.27	TRDMT1	tRNA aspartic acid methyltransferase 1	939	0.58
chr11_111848937_111849153	0.27	DIXDC1	DIX domain containing 1	1012	0.41
chr8_8388322_8388473	0.26	ENSG00000263616	.	51768	0.15
chr1_193304758_193304909	0.26	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	149049	0.04
chr20_39722951_39723102	0.26	PLCG1	phospholipase C, gamma 1	42574	0.14
chr12_122412428_122412631	0.26	BCL7A	B-cell CLL/lymphoma 7A	44799	0.12
chr7_141061897_141062048	0.26	RP5-842K16.2		69096	0.12
chr16_85295971_85296292	0.26	ENSG00000266307	.	43800	0.16
chr15_50392799_50393114	0.26	ATP8B4	ATPase, class I, type 8B, member 4	13745	0.23
chr10_111727206_111727357	0.26	RP11-451M19.3	Uncharacterized protein	13632	0.18
chr2_145270130_145270606	0.26	ZEB2	zinc finger E-box binding homeobox 2	4747	0.27
chr3_59761458_59761609	0.26	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	196050	0.03
chr11_75794475_75794626	0.26	UVRAG	UV radiation resistance associated	32407	0.17
chr12_116596119_116596329	0.26	ENSG00000207967	.	9765	0.21
chr7_41910301_41910559	0.26	AC005027.3		165497	0.04
chr3_16225459_16225610	0.26	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	9318	0.25
chr1_92311778_92311983	0.26	TGFBR3	transforming growth factor, beta receptor III	15270	0.21
chr3_27208769_27208920	0.26	NEK10	NIMA-related kinase 10	49122	0.17
chr15_50194108_50194259	0.25	ATP8B4	ATPase, class I, type 8B, member 4	6107	0.24
chr1_244276859_244277010	0.25	ENSG00000244066	.	9700	0.24
chr14_73613505_73613656	0.25	PSEN1	presenilin 1	620	0.74
chr17_29542627_29542778	0.25	NF1	neurofibromin 1	15148	0.18
chr1_224564194_224564516	0.25	CNIH4	cornichon family AMPA receptor auxiliary protein 4	19760	0.13
chr5_178703659_178703833	0.25	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	68685	0.12
chr1_218891512_218891663	0.25	ENSG00000212610	.	176346	0.03
chr14_76326894_76327045	0.25	RP11-270M14.4		12928	0.25
chr3_171039054_171039205	0.25	TNIK	TRAF2 and NCK interacting kinase	95629	0.08
chr1_168329374_168329525	0.25	ENSG00000207974	.	15313	0.23
chr5_158448429_158448934	0.25	CTD-2363C16.2		35867	0.17
chr11_16377737_16377888	0.25	SOX6	SRY (sex determining region Y)-box 6	14997	0.3
chr16_68771111_68771428	0.24	CDH1	cadherin 1, type 1, E-cadherin (epithelial)	14	0.97
chr9_107630817_107631231	0.24	RP11-217B7.2		58810	0.12
chr3_100601860_100602011	0.24	ABI3BP	ABI family, member 3 (NESH) binding protein	2487	0.39
chr12_78797307_78797458	0.24	NAV3	neuron navigator 3	204526	0.03
chr20_42213255_42213406	0.24	IFT52	intraflagellar transport 52 homolog (Chlamydomonas)	6241	0.18
chr4_57908197_57908348	0.24	ENSG00000251703	.	39414	0.11
chr10_44312151_44312815	0.24	ZNF32	zinc finger protein 32	168179	0.03
chr8_130566904_130567142	0.24	ENSG00000266387	.	57110	0.09
chr19_47138317_47138577	0.24	GNG8	guanine nucleotide binding protein (G protein), gamma 8	505	0.62
chr3_183886938_183887238	0.24	AP2M1	adaptor-related protein complex 2, mu 1 subunit	5389	0.11
chr4_16233802_16234018	0.24	TAPT1-AS1	TAPT1 antisense RNA 1 (head to head)	5242	0.23
chr4_157298853_157299004	0.24	ENSG00000221189	.	81130	0.11
chr9_79451688_79451839	0.24	PRUNE2	prune homolog 2 (Drosophila)	69238	0.12
chr6_106350521_106350672	0.24	ENSG00000200198	.	1652	0.53
chr4_119097025_119097176	0.24	ENSG00000269893	.	103245	0.08
chr17_66591627_66592081	0.23	FAM20A	family with sequence similarity 20, member A	5676	0.25
chr9_4927697_4927848	0.23	ENSG00000238362	.	40325	0.13
chr9_88955484_88955635	0.23	ZCCHC6	zinc finger, CCHC domain containing 6	2479	0.34
chr2_180911324_180911475	0.23	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	39559	0.21
chr2_36720605_36720756	0.23	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	20153	0.19
chrX_37702580_37702731	0.23	DYNLT3	dynein, light chain, Tctex-type 3	4006	0.26
chr2_200604102_200604338	0.23	FTCDNL1	formiminotransferase cyclodeaminase N-terminal like	111376	0.07
chr8_121769766_121770271	0.23	RP11-713M15.1		3475	0.31
chr2_46169357_46169508	0.23	PRKCE	protein kinase C, epsilon	58609	0.15
chr10_81181755_81182122	0.23	ZCCHC24	zinc finger, CCHC domain containing 24	22037	0.18
chr8_119923861_119924012	0.23	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	40503	0.18
chr4_89647157_89647308	0.23	FAM13A-AS1	FAM13A antisense RNA 1	4366	0.21
chr12_4929077_4929347	0.23	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	10870	0.2
chr16_25017302_25017551	0.23	ARHGAP17	Rho GTPase activating protein 17	9226	0.27
chr6_44989881_44990300	0.23	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	66843	0.14
chr5_78052251_78052402	0.23	LHFPL2	lipoma HMGIC fusion partner-like 2	107678	0.07
chr10_49809064_49809215	0.23	ARHGAP22	Rho GTPase activating protein 22	3858	0.26
chr6_34314260_34314411	0.23	NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	46116	0.13
chr1_178102184_178102335	0.22	RASAL2	RAS protein activator like 2	38983	0.22
chr2_158326449_158327167	0.22	CYTIP	cytohesin 1 interacting protein	18533	0.22
chr5_111085283_111085434	0.22	NREP	neuronal regeneration related protein	6590	0.22
chr5_120632218_120632474	0.22	FTMT	ferritin mitochondrial	555304	0.0
chr8_80226395_80226546	0.22	ENSG00000264969	.	216872	0.02
chr12_56917827_56917978	0.22	RBMS2	RNA binding motif, single stranded interacting protein 2	2119	0.23
chr17_2120066_2120283	0.22	AC130689.5		865	0.42
chr2_100625887_100626113	0.22	AFF3	AF4/FMR2 family, member 3	94992	0.08
chr1_25097273_25097424	0.22	ENSG00000238482	.	7122	0.22
chr6_83664770_83664921	0.22	RP11-445L13__B.3		22525	0.24
chr1_173822290_173822441	0.22	GAS5-AS1	GAS5 antisense RNA 1	10021	0.1
chr3_105699405_105699556	0.22	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	111084	0.08
chr15_38437640_38437791	0.22	SPRED1	sprouty-related, EVH1 domain containing 1	106812	0.08
chr2_38054791_38055066	0.22	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	89317	0.09
chr6_37109268_37109585	0.22	PIM1	pim-1 oncogene	28553	0.16
chr18_12421274_12421492	0.22	SLMO1	slowmo homolog 1 (Drosophila)	98	0.96
chr6_155214377_155214528	0.22	ENSG00000238963	.	11839	0.18
chr6_113886507_113886658	0.22	ENSG00000266650	.	37535	0.19
chr16_72972238_72972389	0.22	ENSG00000221799	.	46443	0.15
chr8_108208326_108208625	0.22	ENSG00000211995	.	58251	0.16
chr17_80250217_80250392	0.22	CSNK1D	casein kinase 1, delta	18697	0.1
chr1_2221391_2222142	0.22	RP4-713A8.1		36366	0.09
chr2_98546607_98546758	0.22	ENSG00000238719	.	17102	0.21
chr11_33934050_33934291	0.22	LMO2	LIM domain only 2 (rhombotin-like 1)	20334	0.2
chr1_97604243_97604422	0.22	DPYD-AS1	DPYD antisense RNA 1	42853	0.21
chr17_27887330_27887481	0.22	RP11-68I3.2		160	0.9
chr9_79125250_79125401	0.22	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	51179	0.15
chr10_20884985_20885136	0.22	ENSG00000265372	.	44161	0.21
chr8_37640875_37641038	0.21	GPR124	G protein-coupled receptor 124	753	0.58
chr2_44576037_44576404	0.21	PREPL	prolyl endopeptidase-like	10668	0.2
chr9_125766060_125766211	0.21	RABGAP1	RAB GTPase activating protein 1	29653	0.12
chr9_82676338_82676489	0.21	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	354732	0.01
chr2_235485735_235485886	0.21	ARL4C	ADP-ribosylation factor-like 4C	80113	0.12
chr9_82227138_82227289	0.21	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	38609	0.24
chr12_66296581_66296811	0.21	RP11-366L20.2	Uncharacterized protein	20749	0.16
chr16_83934521_83934672	0.21	MLYCD	malonyl-CoA decarboxylase	1865	0.31
chr13_33768544_33768695	0.21	STARD13	StAR-related lipid transfer (START) domain containing 13	8403	0.23
chr3_45037433_45037728	0.21	EXOSC7	exosome component 7	19858	0.14
chr9_114749197_114749348	0.21	ENSG00000222356	.	9747	0.2
chr13_28054385_28054536	0.21	ENSG00000252499	.	7815	0.19
chr2_65312285_65312436	0.21	RAB1A	RAB1A, member RAS oncogene family	21164	0.16
chr16_72928505_72928656	0.21	ENSG00000251868	.	72689	0.09
chr19_54657228_54657379	0.21	CNOT3	CCR4-NOT transcription complex, subunit 3	158	0.88
chr17_30586530_30586681	0.21	RHBDL3	rhomboid, veinlet-like 3 (Drosophila)	6590	0.16
chr1_170879044_170879195	0.21	MROH9	maestro heat-like repeat family member 9	25493	0.24
chr13_31255786_31256279	0.21	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	53613	0.14
chr5_34497593_34497744	0.21	RAI14	retinoic acid induced 14	158674	0.04
chr2_208116387_208116719	0.21	AC007879.5		2423	0.32
chr11_71778137_71778288	0.21	NUMA1	nuclear mitotic apparatus protein 1	2921	0.12
chr5_125339534_125339685	0.21	ENSG00000265637	.	192919	0.03
chr2_157313118_157313429	0.21	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	16811	0.19
chr13_88323755_88324230	0.21	SLITRK5	SLIT and NTRK-like family, member 5	878	0.73
chr17_69498538_69498689	0.21	ENSG00000222563	.	191304	0.03
chr10_115033205_115033385	0.21	ENSG00000238380	.	79889	0.11
chr9_79432035_79432186	0.21	PCA3	prostate cancer antigen 3 (non-protein coding)	52758	0.16
chr15_70620773_70621274	0.21	ENSG00000200216	.	135448	0.05
chr12_26811451_26811602	0.21	RP11-666F17.1		35224	0.22
chr12_124483374_124483666	0.21	ZNF664	zinc finger protein 664	25678	0.08
chr4_83281916_83282171	0.21	HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	1251	0.46
chr19_19220612_19220870	0.21	TMEM161A	transmembrane protein 161A	22469	0.11
chr4_15435517_15435668	0.21	RP11-665G4.1		6054	0.18
chr14_103162755_103162994	0.21	ENSG00000202459	.	1149	0.54
chr16_50840051_50840280	0.21	RP11-327F22.4		2916	0.22
chr4_71533612_71533824	0.21	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	1026	0.42
chr7_94035985_94036136	0.21	COL1A2	collagen, type I, alpha 2	12187	0.27
chr9_91752254_91752405	0.21	RP11-82L18.2		27480	0.2
chr1_213499715_213500068	0.20	RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1	275287	0.01
chr3_58030666_58030922	0.20	FLNB	filamin B, beta	33262	0.2
chr1_109261913_109262064	0.20	FNDC7	fibronectin type III domain containing 7	3045	0.21
chr17_8576822_8576973	0.20	MYH10	myosin, heavy chain 10, non-muscle	42818	0.14
chr12_19805873_19806024	0.20	ENSG00000200885	.	71421	0.13
chr15_50156516_50156667	0.20	ATP8B4	ATPase, class I, type 8B, member 4	12301	0.22
chr13_98867933_98868084	0.20	ENSG00000263399	.	7230	0.16
chr5_9363080_9363231	0.20	CTD-2201E9.4		232	0.95
chr9_77791417_77791568	0.20	ENSG00000200041	.	5045	0.24
chr8_27497354_27497505	0.20	SCARA3	scavenger receptor class A, member 3	5731	0.18
chr17_40511255_40511412	0.20	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	29099	0.1
chr10_97579295_97579446	0.20	RP11-429G19.3		13895	0.21
chr3_193856714_193857102	0.20	HES1	hes family bHLH transcription factor 1	2974	0.25
chr10_17151320_17151471	0.20	CUBN	cubilin (intrinsic factor-cobalamin receptor)	18441	0.23
chr10_128259000_128259151	0.20	ENSG00000221717	.	13442	0.26
chr6_126142988_126143327	0.20	NCOA7-AS1	NCOA7 antisense RNA 1	3153	0.24
chr5_77796656_77796807	0.20	LHFPL2	lipoma HMGIC fusion partner-like 2	48243	0.18
chr7_2197941_2198092	0.20	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	48780	0.15
chr11_8091043_8091194	0.20	RP11-236J17.5		9533	0.15
chr1_198573317_198573468	0.20	PTPRC	protein tyrosine phosphatase, receptor type, C	34409	0.19
chr10_80517839_80518027	0.20	ENSG00000223243	.	7574	0.33
chr18_56031230_56031381	0.20	RP11-845C23.2		7493	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.1	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.3	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.2	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0060760	positive regulation of response to cytokine stimulus(GO:0060760)
0.0	0.2	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:1903670	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.1	GO:0071221	response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.4	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.3	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.4	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.3	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0034694	response to prostaglandin(GO:0034694)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.3	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.0	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.3	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.4	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0004556	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.9	NABA COLLAGENS	Genes encoding collagen proteins
0.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling