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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for LMX1B_MNX1_RAX2

Z-value: 0.50

Motif logo

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Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LMX1B
MNX1
ENSG00000130675.10 MNX1
RAX2
ENSG00000173976.11 RAX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
LMX1Bchr9_129388786_129388937121130.157468-0.521.5e-01Click!
LMX1Bchr9_129387667_129387818109940.159314-0.501.7e-01Click!
LMX1Bchr9_129388528_129388727118790.157845-0.412.7e-01Click!
LMX1Bchr9_129386356_12938650796830.161683-0.383.2e-01Click!
LMX1Bchr9_129378843_12937899421700.252632-0.363.4e-01Click!
MNX1chr7_156801782_156801933880.9528090.353.6e-01Click!
MNX1chr7_156801023_1568011746710.6000260.255.1e-01Click!
MNX1chr7_156800821_1568009728730.4860040.215.8e-01Click!
MNX1chr7_156801980_156802430760.9507270.127.7e-01Click!
MNX1chr7_156801401_1568015622880.861126-0.059.0e-01Click!

Activity of the LMX1B_MNX1_RAX2 motif across conditions

Conditions sorted by the z-value of the LMX1B_MNX1_RAX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_148365723_148365874 0.24 RP11-44B19.1
15895
 0.18
chr17_28275117_28275440 0.23 EFCAB5
 EF-hand calcium binding domain 5
 6655
 0.17
chr3_154690294_154690445 0.21 MME
 membrane metallo-endopeptidase
 51544
 0.19
chrX_55741083_55741234 0.19 RRAGB
 Ras-related GTP binding B
 3014
 0.33
chr7_105903512_105903663 0.19 NAMPT
 nicotinamide phosphoribosyltransferase
 21780
 0.19
chr5_169227490_169227641 0.18 CTB-37A13.1
21196
 0.23
chr2_8007405_8007668 0.18 ENSG00000221255
 .
 290564
 0.01
chrX_96151518_96151669 0.18 RPA4
 replication protein A4, 30kDa
 12686
 0.31
chr8_62569308_62569459 0.18 ASPH
 aspartate beta-hydroxylase
 10017
 0.23
chr6_2509288_2509439 0.18 ENSG00000266252
 .
 99494
 0.08
chr9_123478112_123478263 0.17 MEGF9
 multiple EGF-like-domains 9
 1439
 0.51
chr11_122897468_122897619 0.17 ENSG00000200879
 .
 31326
 0.12
chr6_17972496_17972680 0.16 KIF13A
 kinesin family member 13A
 15106
 0.27
chr9_28922506_28922753 0.16 ENSG00000215939
 .
 33676
 0.22
chr16_4998738_4998889 0.16 ENSG00000200980
 .
 3079
 0.19
chr9_94178983_94179134 0.16 NFIL3
 nuclear factor, interleukin 3 regulated
 7086
 0.3
chr9_38042251_38042402 0.16 SHB
 Src homology 2 domain containing adaptor protein B
 26882
 0.21
chr12_81262405_81262556 0.15 LIN7A
 lin-7 homolog A (C. elegans)
 20647
 0.19
chr15_101143578_101144308 0.15 ASB7
 ankyrin repeat and SOCS box containing 7
 1129
 0.36
chr5_17282736_17283060 0.15 ENSG00000252908
 .
 42178
 0.15
chr2_134912163_134912443 0.15 ENSG00000263813
 .
 27607
 0.2
chr9_41085505_41085742 0.15 RP11-95K23.5
199734
 0.03
chr2_124505371_124505522 0.15 ENSG00000221689
 .
 65655
 0.14
chr5_127457688_127457839 0.15 SLC12A2
 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
 38223
 0.23
chr12_80333289_80333440 0.15 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 4124
 0.23
chr5_66255925_66256427 0.15 MAST4
 microtubule associated serine/threonine kinase family member 4
 1360
 0.56
chr18_22012413_22012586 0.15 RP11-178F10.1
2829
 0.18
chrX_7163379_7163530 0.15 STS
 steroid sulfatase (microsomal), isozyme S
 25957
 0.25
chr7_25345986_25346137 0.15 ENSG00000202233
 .
 41786
 0.18
chr6_17906953_17907342 0.14 KIF13A
 kinesin family member 13A
 80547
 0.1
chr20_46413000_46413151 0.14 SULF2
 sulfatase 2
 1158
 0.56
chr10_129077210_129077361 0.14 FAM196A
 family with sequence similarity 196, member A
 82863
 0.11
chr13_72218273_72218424 0.14 DACH1
 dachshund homolog 1 (Drosophila)
 222559
 0.02
chr5_40608102_40608403 0.14 ENSG00000199552
 .
 46813
 0.16
chr6_25005285_25005494 0.14 ENSG00000244618
 .
 26121
 0.17
chr1_109632204_109632387 0.13 TMEM167B
 transmembrane protein 167B
 130
 0.91
chr13_30472600_30472751 0.13 LINC00572
 long intergenic non-protein coding RNA 572
 28113
 0.22
chr1_180279497_180279775 0.13 RP5-1180C10.2
34277
 0.19
chr17_74601770_74601921 0.13 ST6GALNAC2
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
 19635
 0.08
chr5_115823878_115824029 0.13 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 9580
 0.25
chr20_39135706_39135857 0.13 ENSG00000252434
 .
 90266
 0.1
chr12_104200199_104200350 0.13 RP11-650K20.2
13114
 0.14
chr7_8328595_8328746 0.13 ICA1
 islet cell autoantigen 1, 69kDa
 26353
 0.17
chrX_120811108_120811259 0.13 ENSG00000221217
 .
 191537
 0.03
chr2_210868461_210869072 0.13 RPE
 ribulose-5-phosphate-3-epimerase
 1380
 0.42
chr5_53987308_53987459 0.13 ENSG00000221073
 .
 161393
 0.04
chr9_21383132_21383283 0.13 IFNA2
 interferon, alpha 2
 2189
 0.22
chr3_177443249_177443545 0.13 ENSG00000200288
 .
 101200
 0.08
chr4_83969657_83969808 0.13 COPS4
 COP9 signalosome subunit 4
 13354
 0.17
chr7_36108267_36108418 0.13 PP13004
10352
 0.22
chr13_49475290_49475441 0.13 ENSG00000265585
 .
 28983
 0.2
chr2_240340277_240340428 0.13 AC062017.1
 Uncharacterized protein
 16853
 0.19
chr2_152510948_152511099 0.13 NEB
 nebulin
 70890
 0.13
chr2_37576208_37576507 0.12 QPCT
 glutaminyl-peptide cyclotransferase
 4505
 0.2
chr3_12242557_12242708 0.12 TIMP4
 TIMP metallopeptidase inhibitor 4
 41781
 0.18
chr16_69775894_69776045 0.12 NOB1
 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
 12874
 0.1
chr13_32715851_32716002 0.12 FRY
 furry homolog (Drosophila)
 80925
 0.1
chr9_107830314_107830790 0.12 ENSG00000201583
 .
 28485
 0.23
chr8_90851049_90851200 0.12 ENSG00000207359
 .
 61928
 0.12
chr6_35002148_35002432 0.12 TCP11
 t-complex 11, testis-specific
 86532
 0.08
chr2_14212942_14213093 0.12 ENSG00000251859
 .
 201832
 0.03
chr13_110651559_110651710 0.12 ENSG00000201161
 .
 84191
 0.1
chr7_37760403_37760554 0.12 GPR141
 G protein-coupled receptor 141
 19518
 0.23
chr14_103106612_103106763 0.12 RCOR1
 REST corepressor 1
 47454
 0.12
chr9_137251018_137251277 0.12 ENSG00000263897
 .
 20110
 0.22
chr8_9331082_9331233 0.12 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
 82267
 0.09
chr8_97536479_97536735 0.12 SDC2
 syndecan 2
 30371
 0.22
chr20_6888062_6888352 0.12 ENSG00000251833
 .
 46546
 0.2
chr4_123694862_123695013 0.12 BBS12
 Bardet-Biedl syndrome 12
 40985
 0.14
chr9_590173_590324 0.12 ENSG00000202172
 .
 31422
 0.15
chr3_23930377_23930528 0.12 RPL15
 ribosomal protein L15
 27584
 0.16
chr2_8012045_8012196 0.12 ENSG00000221255
 .
 295148
 0.01
chr22_36793445_36793596 0.12 MYH9
 myosin, heavy chain 9, non-muscle
 9457
 0.18
chr7_80350905_80351077 0.12 CD36
 CD36 molecule (thrombospondin receptor)
 48299
 0.19
chr18_10213675_10214158 0.12 ENSG00000239031
 .
 176081
 0.03
chr4_10009068_10009219 0.12 RP11-448G15.1
1037
 0.53
chr4_39152584_39152984 0.12 RP11-360F5.1
24346
 0.17
chr21_39659541_39659821 0.12 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 8798
 0.29
chr10_64252258_64252409 0.12 ZNF365
 zinc finger protein 365
 27874
 0.24
chr13_107573389_107573540 0.12 ENSG00000239050
 .
 53910
 0.18
chr4_101903241_101903392 0.12 EMCN-IT1
 EMCN intronic transcript 1 (non-protein coding)
 167879
 0.04
chr11_33934050_33934291 0.12 LMO2
 LIM domain only 2 (rhombotin-like 1)
 20334
 0.2
chr17_65372251_65373170 0.12 PITPNC1
 phosphatidylinositol transfer protein, cytoplasmic 1
 865
 0.53
chr8_28272280_28272431 0.12 ENSG00000207361
 .
 1610
 0.28
chr11_32843513_32843664 0.11 PRRG4
 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
 7901
 0.23
chr19_18239230_18239381 0.11 AC007192.6
23196
 0.1
chr4_101813891_101814042 0.11 EMCN-IT1
 EMCN intronic transcript 1 (non-protein coding)
 78529
 0.11
chr18_2154076_2154227 0.11 METTL4
 methyltransferase like 4
 400540
 0.01
chr2_197857511_197857662 0.11 ANKRD44
 ankyrin repeat domain 44
 7640
 0.27
chr3_48800674_48800825 0.11 PRKAR2A
 protein kinase, cAMP-dependent, regulatory, type II, alpha
 2034
 0.27
chr20_4811132_4811283 0.11 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 6916
 0.2
chr2_100664977_100665128 0.11 AFF3
 AF4/FMR2 family, member 3
 55940
 0.14
chr14_70110903_70111120 0.11 KIAA0247
 KIAA0247
 32698
 0.18
chr5_102181314_102181465 0.11 PAM
 peptidylglycine alpha-amidating monooxygenase
 18852
 0.29
chr4_65272983_65273134 0.11 TECRL
 trans-2,3-enoyl-CoA reductase-like
 2058
 0.4
chr1_88995690_88995841 0.11 RP11-76N22.2
40778
 0.18
chr4_74569730_74569881 0.11 IL8
 interleukin 8
 36418
 0.18
chr6_87895108_87895259 0.11 ZNF292
 zinc finger protein 292
 29844
 0.16
chr8_93968938_93969089 0.11 TRIQK
 triple QxxK/R motif containing
 8804
 0.25
chr15_78594610_78594888 0.11 WDR61
 WD repeat domain 61
 2613
 0.18
chr3_187492287_187492506 0.11 BCL6
 B-cell CLL/lymphoma 6
 28881
 0.2
chrX_147724893_147725044 0.11 AFF2
 AF4/FMR2 family, member 2
 75647
 0.11
chr10_31273280_31273431 0.11 ZNF438
 zinc finger protein 438
 0
 0.99
chr7_26143414_26143565 0.11 ENSG00000266430
 .
 43530
 0.14
chr7_33973779_33973930 0.11 BMPER
 BMP binding endothelial regulator
 28709
 0.26
chr11_69414414_69414565 0.11 CCND1
 cyclin D1
 41366
 0.17
chr1_87801300_87801913 0.11 LMO4
 LIM domain only 4
 4255
 0.35
chr10_31272970_31273270 0.11 ZNF438
 zinc finger protein 438
 235
 0.96
chr14_33625609_33625904 0.11 NPAS3
 neuronal PAS domain protein 3
 57128
 0.18
chr1_31870163_31870721 0.11 SERINC2
 serine incorporator 2
 11970
 0.15
chr2_201958936_201959087 0.11 ENSG00000252148
 .
 14446
 0.12
chr7_155382227_155382378 0.11 AC009403.2
 Protein LOC100506302
 54793
 0.11
chr19_19539763_19539914 0.11 GATAD2A
 GATA zinc finger domain containing 2A
 1502
 0.3
chr4_26727880_26728031 0.11 ENSG00000200999
 .
 24024
 0.23
chr12_27197460_27197611 0.11 MED21
 mediator complex subunit 21
 22052
 0.15
chr4_16034494_16034749 0.11 ENSG00000251758
 .
 24211
 0.19
chr3_39256267_39256418 0.11 XIRP1
 xin actin-binding repeat containing 1
 22255
 0.18
chr4_101993104_101993255 0.11 EMCN-IT1
 EMCN intronic transcript 1 (non-protein coding)
 257742
 0.02
chr14_23583904_23584167 0.11 CEBPE
 CCAAT/enhancer binding protein (C/EBP), epsilon
 4790
 0.11
chr7_127763401_127763552 0.11 ENSG00000207588
 .
 41563
 0.16
chrX_14818705_14818856 0.11 ENSG00000221278
 .
 35541
 0.19
chr6_138820271_138821054 0.11 NHSL1
 NHS-like 1
 31
 0.98
chr2_33309027_33309178 0.11 LTBP1
 latent transforming growth factor beta binding protein 1
 50371
 0.16
chr14_103586056_103586207 0.11 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 3667
 0.2
chr7_21979875_21980026 0.11 CDCA7L
 cell division cycle associated 7-like
 4541
 0.34
chr12_117472876_117473027 0.10 TESC
 tescalcin
 11685
 0.24
chr1_100293238_100293389 0.10 ENSG00000252226
 .
 1708
 0.32
chr8_80718909_80719060 0.10 ENSG00000238884
 .
 6554
 0.27
chr6_97580328_97580479 0.10 KLHL32
 kelch-like family member 32
 67899
 0.13
chr7_37748458_37748609 0.10 GPR141
 G protein-coupled receptor 141
 25058
 0.2
chr20_44601777_44602076 0.10 ZNF335
 zinc finger protein 335
 1093
 0.38
chr14_51406161_51406312 0.10 PYGL
 phosphorylase, glycogen, liver
 4938
 0.21
chr6_166670086_166670237 0.10 ENSG00000201292
 .
 47270
 0.13
chr5_109078948_109079099 0.10 ENSG00000202512
 .
 43488
 0.16
chr4_85836939_85837233 0.10 ENSG00000252062
 .
 29447
 0.21
chr1_180382000_180382151 0.10 ENSG00000265435
 .
 25450
 0.21
chr7_26351236_26351387 0.10 SNX10
 sorting nexin 10
 18637
 0.22
chr2_165699907_165700058 0.10 COBLL1
 cordon-bleu WH2 repeat protein-like 1
 207
 0.93
chr18_61561537_61561693 0.10 SERPINB10
 serpin peptidase inhibitor, clade B (ovalbumin), member 10
 2793
 0.24
chr19_10891817_10891968 0.10 ENSG00000265879
 .
 962
 0.4
chr15_77646528_77646679 0.10 PEAK1
 pseudopodium-enriched atypical kinase 1
 65839
 0.12
chr5_139968834_139969062 0.10 ENSG00000200235
 .
 9696
 0.08
chr2_190637879_190638030 0.10 AC013468.1
5203
 0.12
chr2_144454482_144454633 0.10 RP11-434H14.1
14049
 0.22
chr18_46195874_46196025 0.10 ENSG00000266276
 .
 1022
 0.6
chr19_43853396_43853679 0.10 CD177
 CD177 molecule
 4288
 0.2
chr9_129190475_129190626 0.10 ENSG00000252985
 .
 1378
 0.46
chr18_456798_457125 0.10 RP11-720L2.2
32545
 0.16
chr3_11734918_11735069 0.10 VGLL4
 vestigial like 4 (Drosophila)
 17018
 0.25
chr7_156836903_156837054 0.10 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 33479
 0.13
chr3_158546491_158546642 0.10 MFSD1
 major facilitator superfamily domain containing 1
 19540
 0.17
chr3_81783533_81783684 0.10 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 9172
 0.33
chr14_59803635_59803786 0.10 ENSG00000252869
 .
 63031
 0.12
chr1_33793881_33794032 0.10 ENSG00000266239
 .
 4137
 0.14
chr15_69730252_69730403 0.10 RPLP1
 ribosomal protein, large, P1
 14796
 0.12
chr11_3748512_3748663 0.10 ENSG00000251934
 .
 12482
 0.11
chr9_114557676_114557827 0.10 C9orf84
 chromosome 9 open reading frame 84
 463
 0.84
chr5_57134689_57134840 0.10 ENSG00000266864
 .
 34109
 0.24
chr22_40574959_40575808 0.10 TNRC6B
 trinucleotide repeat containing 6B
 1437
 0.53
chr20_45754256_45754424 0.10 ENSG00000264901
 .
 41269
 0.18
chr13_49838164_49838315 0.10 CDADC1
 cytidine and dCMP deaminase domain containing 1
 16055
 0.21
chr8_38264429_38264741 0.10 RP11-350N15.6
1675
 0.23
chr2_64074407_64074558 0.10 UGP2
 UDP-glucose pyrophosphorylase 2
 1274
 0.55
chr10_78792555_78792706 0.10 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 46652
 0.17
chr7_8290002_8290153 0.10 ICA1
 islet cell autoantigen 1, 69kDa
 11605
 0.18
chr1_21067705_21067856 0.10 RP5-930J4.4
1700
 0.27
chr1_76545726_76545919 0.10 ST6GALNAC3
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
 5418
 0.32
chr1_234667803_234667954 0.10 TARBP1
 TAR (HIV-1) RNA binding protein 1
 53029
 0.12
chr1_200865216_200865405 0.10 C1orf106
 chromosome 1 open reading frame 106
 1361
 0.42
chr2_153267355_153267720 0.10 FMNL2
 formin-like 2
 75786
 0.12
chr5_158647032_158647183 0.10 RNF145
 ring finger protein 145
 10046
 0.16
chr3_47123059_47123210 0.10 ENSG00000251938
 .
 6964
 0.22
chr12_42228024_42228175 0.10 ENSG00000252364
 .
 175621
 0.03
chr3_168752701_168752852 0.10 MECOM
 MDS1 and EVI1 complex locus
 93046
 0.1
chr11_46479636_46479787 0.10 ENSG00000265014
 .
 6272
 0.19
chr3_138595962_138596113 0.10 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 42257
 0.15
chr1_83043773_83044235 0.10 LPHN2
 latrophilin 2
 598431
 0.0
chr2_225451534_225451729 0.10 CUL3
 cullin 3
 1521
 0.57
chr2_163197962_163198113 0.10 GCA
 grancalcin, EF-hand calcium binding protein
 2561
 0.33
chr3_122029022_122029173 0.10 CSTA
 cystatin A (stefin A)
 14994
 0.16
chr3_148706459_148706610 0.10 GYG1
 glycogenin 1
 2594
 0.29
chrX_16661091_16661259 0.10 S100G
 S100 calcium binding protein G
 7106
 0.18
chr4_185186357_185186631 0.09 ENSG00000221523
 .
 2090
 0.34
chr2_163263039_163263190 0.09 GCA
 grancalcin, EF-hand calcium binding protein
 50166
 0.15
chr10_120480954_120481105 0.09 CACUL1
 CDK2-associated, cullin domain 1
 33729
 0.18
chr7_37726411_37726562 0.09 GPR141
 G protein-coupled receptor 141
 3011
 0.28
chr22_30257161_30257312 0.09 MTMR3
 myotubularin related protein 3
 21908
 0.14
chr5_115627433_115627584 0.09 ENSG00000212457
 .
 103259
 0.07
chr17_29906221_29906372 0.09 ENSG00000199187
 .
 3866
 0.14
chr16_3081576_3081727 0.09 RP11-473M20.5
831
 0.27
chr17_2285977_2286170 0.09 RP1-59D14.1
2068
 0.18
chr4_15662221_15662454 0.09 FBXL5
 F-box and leucine-rich repeat protein 5
 847
 0.63
chrX_38576524_38576675 0.09 MID1IP1
 MID1 interacting protein 1
 84086
 0.09
chr2_223688143_223688294 0.09 ACSL3
 acyl-CoA synthetase long-chain family member 3
 37434
 0.18
chr6_51167339_51167725 0.09 ENSG00000212532
 .
 161956
 0.04
chr1_233375664_233375815 0.09 PCNXL2
 pecanex-like 2 (Drosophila)
 12724
 0.29
chr9_90215657_90216062 0.09 DAPK1-IT1
 DAPK1 intronic transcript 1 (non-protein coding)
 47490
 0.16
chr17_66307289_66307440 0.09 ARSG
 arylsulfatase G
 19705
 0.16
chr1_64697428_64697579 0.09 UBE2U
 ubiquitin-conjugating enzyme E2U (putative)
 10956
 0.25
chr4_48382974_48383176 0.09 SLAIN2
 SLAIN motif family, member 2
 2620
 0.36

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0032493 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.1 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.0 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP