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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for MAFA

Z-value: 1.72

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Transcription factors associated with MAFA

Gene Symbol	Gene ID	Gene Info
MAFA Ensembl NCBI GeneCards UniProt	ENSG00000182759.3	MAF bZIP transcription factor A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_144512410_144512561	MAFA	91	0.946150	0.81	8.7e-03	Click!
chr8_144511807_144511958	MAFA	694	0.541733	0.72	2.8e-02	Click!
chr8_144513885_144514179	MAFA	1456	0.271718	0.67	4.6e-02	Click!
chr8_144510187_144510571	MAFA	2197	0.185806	0.67	4.8e-02	Click!
chr8_144517339_144517490	MAFA	4838	0.126381	0.67	5.0e-02	Click!

Activity of the MAFA motif across conditions

Conditions sorted by the z-value of the MAFA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr21_46955498_46955649	0.74	SLC19A1	solute carrier family 19 (folate transporter), member 1	1044	0.57
chr3_52140801_52140952	0.66	LINC00696	long intergenic non-protein coding RNA 696	43309	0.09
chr3_48263739_48263890	0.64	CAMP	cathelicidin antimicrobial peptide	1023	0.42
chr4_5054457_5054608	0.58	STK32B	serine/threonine kinase 32B	1363	0.53
chr3_127395993_127396144	0.51	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	3115	0.23
chr22_39363886_39364037	0.50	APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A	10434	0.12
chr2_95941719_95941977	0.50	PROM2	prominin 2	1603	0.42
chr9_137262651_137262802	0.49	ENSG00000263897	.	8531	0.25
chr1_3526502_3526724	0.49	MEGF6	multiple EGF-like-domains 6	1446	0.31
chr10_79397018_79397495	0.48	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	4	0.99
chr20_56888582_56888769	0.48	RAB22A	RAB22A, member RAS oncogene family	3923	0.23
chr11_47420144_47420472	0.48	ENSG00000264583	.	2213	0.15
chr16_89427857_89428160	0.47	ANKRD11	ankyrin repeat domain 11	32614	0.1
chr19_7401594_7401745	0.47	CTB-133G6.1		12179	0.16
chr7_150148399_150148619	0.46	GIMAP8	GTPase, IMAP family member 8	791	0.61
chr10_29971037_29971284	0.46	ENSG00000222092	.	29684	0.19
chr19_1240543_1240694	0.46	ATP5D	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	1131	0.27
chr1_160905464_160905865	0.46	RP11-544M22.1		3409	0.18
chr1_44874319_44874616	0.46	RNF220	ring finger protein 220	3303	0.23
chr8_145520955_145521106	0.46	HSF1	heat shock transcription factor 1	4768	0.09
chr19_58324388_58324619	0.46	ZNF552	zinc finger protein 552	269	0.83
chr15_85264710_85265101	0.46	SEC11A	SEC11 homolog A (S. cerevisiae)	4958	0.15
chr17_55168522_55168933	0.45	AKAP1	A kinase (PRKA) anchor protein 1	4478	0.21
chr21_47059988_47060139	0.44	PCBP3	poly(rC) binding protein 3	3545	0.31
chr11_64629664_64630187	0.43	EHD1	EH-domain containing 1	13213	0.09
chr3_43257495_43257646	0.43	ENSG00000222331	.	5207	0.26
chr21_34764530_34764681	0.42	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	10597	0.18
chr6_116772160_116772456	0.42	ENSG00000265516	.	6677	0.14
chr17_29819355_29819635	0.42	RAB11FIP4	RAB11 family interacting protein 4 (class II)	4369	0.16
chr18_9850464_9850615	0.42	ENSG00000252680	.	5696	0.19
chr2_106475830_106476129	0.42	AC009505.2		2346	0.36
chr15_40550177_40550328	0.42	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	4867	0.11
chr2_37897671_37897822	0.42	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	1588	0.51
chr10_135092995_135093366	0.42	ADAM8	ADAM metallopeptidase domain 8	2808	0.14
chr22_37267478_37267629	0.41	NCF4	neutrophil cytosolic factor 4, 40kDa	626	0.53
chr18_72346363_72346608	0.41	ZNF407	zinc finger protein 407	3509	0.35
chr12_11939644_11939800	0.40	ETV6	ets variant 6	34287	0.22
chr11_121316146_121316378	0.40	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	6650	0.25
chr10_45920968_45921180	0.39	RP11-67C2.2		27495	0.19
chr10_73499250_73499401	0.39	C10orf105	chromosome 10 open reading frame 105	1744	0.38
chr1_43398187_43398359	0.39	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	1477	0.41
chr17_7976584_7976755	0.39	AC129492.6		6131	0.1
chr2_46635430_46635581	0.39	ENSG00000241791	.	40145	0.15
chr3_182928481_182928632	0.39	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	42476	0.13
chr1_68026967_68027118	0.39	ENSG00000207504	.	20232	0.23
chr11_44600925_44601210	0.39	CD82	CD82 molecule	6439	0.22
chr20_1315455_1315606	0.39	AL136531.1	HCG2043693; Uncharacterized protein	2025	0.23
chrX_68505919_68506070	0.39	PJA1	praja ring finger 1, E3 ubiquitin protein ligase	120358	0.06
chr8_131000097_131000248	0.39	ENSG00000253043	.	16675	0.16
chr14_60337600_60337751	0.38	RTN1	reticulon 1	9	0.98
chr2_60727304_60727455	0.38	AC009970.1		4558	0.28
chr19_35756219_35756370	0.38	AD000684.2		2545	0.13
chr5_14178843_14178994	0.37	TRIO	trio Rho guanine nucleotide exchange factor	4989	0.36
chr15_52068308_52068538	0.37	CTD-2308G16.1		23741	0.12
chr11_46362037_46362188	0.37	DGKZ	diacylglycerol kinase, zeta	1964	0.27
chr19_54880893_54881262	0.37	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	981	0.39
chr2_121381891_121382042	0.36	ENSG00000201006	.	26883	0.24
chr2_127643425_127643576	0.36	AC114783.1	Protein LOC339760	12972	0.28
chr6_37023193_37023344	0.36	COX6A1P2	cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2	10661	0.2
chr1_12211169_12211320	0.36	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	15816	0.15
chr17_74487092_74487507	0.36	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	1937	0.2
chr1_153485547_153485698	0.36	ENSG00000263841	.	12382	0.09
chr12_102065427_102065608	0.36	RP11-755O11.2		11769	0.15
chr15_75641179_75641332	0.35	NEIL1	nei endonuclease VIII-like 1 (E. coli)	515	0.67
chr19_49931671_49931926	0.35	GFY	golgi-associated, olfactory signaling regulator	4792	0.07
chr4_169799427_169799622	0.35	ENSG00000201176	.	6982	0.22
chr20_62574273_62574438	0.35	ENSG00000207554	.	276	0.72
chr11_953594_953745	0.35	ENSG00000264671	.	2305	0.18
chr10_8103926_8104304	0.35	GATA3	GATA binding protein 3	7346	0.33
chr21_45876262_45876442	0.35	LRRC3	leucine rich repeat containing 3	983	0.28
chr5_176905874_176906027	0.35	DBN1	drebrin 1	4548	0.11
chr14_100072738_100072889	0.35	CCDC85C	coiled-coil domain containing 85C	2450	0.27
chr18_60799610_60799761	0.34	RP11-299P2.1		18868	0.23
chr4_38622899_38623179	0.34	RP11-617D20.1		3157	0.28
chr3_71752260_71752853	0.34	EIF4E3	eukaryotic translation initiation factor 4E family member 3	21970	0.2
chr17_4754312_4754498	0.34	MINK1	misshapen-like kinase 1	17526	0.08
chr21_16582150_16582301	0.34	NRIP1	nuclear receptor interacting protein 1	144904	0.05
chr1_209826804_209826967	0.34	LAMB3	laminin, beta 3	1074	0.44
chr11_110166518_110166669	0.34	RDX	radixin	744	0.8
chr4_143345126_143345417	0.33	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	7141	0.35
chr7_65445478_65445877	0.33	GUSB	glucuronidase, beta	1521	0.44
chr7_111825883_111826034	0.33	DOCK4	dedicator of cytokinesis 4	20492	0.21
chr14_24785019_24785170	0.33	LTB4R	leukotriene B4 receptor	1188	0.21
chr18_54492142_54492605	0.33	RP11-383D22.1		48828	0.14
chr3_134324324_134324540	0.33	EPHB1	EPH receptor B1	9775	0.22
chr17_55188705_55188891	0.33	AKAP1	A kinase (PRKA) anchor protein 1	3052	0.27
chr11_118958578_118958866	0.33	HMBS	hydroxymethylbilane synthase	25	0.93
chr4_183727825_183728099	0.33	ENSG00000221186	.	19419	0.21
chr20_37435383_37435534	0.33	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	1091	0.52
chr11_128357006_128357190	0.33	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	18191	0.24
chr9_130616494_130616662	0.33	ENG	endoglin	337	0.74
chr11_133897961_133898138	0.33	JAM3	junctional adhesion molecule 3	40771	0.15
chr6_19838236_19838410	0.33	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	706	0.56
chr13_41180871_41181022	0.33	FOXO1	forkhead box O1	59788	0.12
chr22_46543772_46543923	0.33	PPARA	peroxisome proliferator-activated receptor alpha	2577	0.2
chr3_183253186_183253337	0.33	KLHL6-AS1	KLHL6 antisense RNA 1	13262	0.16
chr1_35150748_35150899	0.32	ENSG00000207941	.	15528	0.19
chr10_80908302_80908453	0.32	ZMIZ1	zinc finger, MIZ-type containing 1	79585	0.1
chr19_51228108_51228259	0.32	CLEC11A	C-type lectin domain family 11, member A	1403	0.27
chr18_43923958_43924235	0.32	RNF165	ring finger protein 165	9909	0.28
chr22_45074770_45074921	0.32	PRR5	proline rich 5 (renal)	1880	0.36
chr17_76123196_76123347	0.32	TMC6	transmembrane channel-like 6	170	0.91
chr5_140934914_140935065	0.32	CTD-2024I7.13		2889	0.17
chr21_46346499_46346961	0.32	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	1903	0.19
chr6_170123147_170123298	0.31	PHF10	PHD finger protein 10	805	0.43
chr15_77286822_77287094	0.31	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	468	0.82
chr1_227747527_227747704	0.31	ENSG00000202264	.	1267	0.48
chr21_19148494_19148866	0.31	AL109761.5		17125	0.22
chr10_116259650_116260051	0.31	ABLIM1	actin binding LIM protein 1	12098	0.26
chr1_1832753_1832904	0.31	RP1-140A9.1		9918	0.12
chr4_7043959_7044306	0.31	TADA2B	transcriptional adaptor 2B	506	0.46
chr1_9686959_9687110	0.31	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	24756	0.14
chr18_77559512_77559674	0.31	KCNG2	potassium voltage-gated channel, subfamily G, member 2	64075	0.12
chr9_71789095_71789246	0.31	TJP2	tight junction protein 2	23	0.99
chr22_37261033_37261184	0.31	NCF4	neutrophil cytosolic factor 4, 40kDa	4078	0.16
chr1_170634081_170634326	0.31	PRRX1	paired related homeobox 1	1125	0.64
chr19_42144649_42144840	0.30	CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	11302	0.14
chr2_31274988_31275144	0.30	ENSG00000216093	.	16647	0.23
chr1_205474854_205475005	0.30	CDK18	cyclin-dependent kinase 18	999	0.52
chr3_197465112_197465263	0.30	FYTTD1	forty-two-three domain containing 1	1137	0.38
chr8_33412460_33412753	0.30	RNF122	ring finger protein 122	12037	0.13
chr3_46278155_46278310	0.30	CCR3	chemokine (C-C motif) receptor 3	5640	0.23
chr22_46846609_46846760	0.30	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	84507	0.08
chr2_149634254_149634486	0.30	KIF5C	kinesin family member 5C	1551	0.38
chr11_118827290_118827441	0.30	UPK2	uroplakin 2	339	0.71
chr10_13837379_13837803	0.30	FRMD4A	FERM domain containing 4A	63321	0.09
chr14_91830928_91831128	0.30	ENSG00000265856	.	30971	0.18
chr17_76493340_76493491	0.30	DNAH17-AS1	DNAH17 antisense RNA 1	1496	0.34
chr20_62696555_62696706	0.30	TCEA2	transcription elongation factor A (SII), 2	934	0.36
chr20_44640102_44640397	0.30	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	2702	0.18
chr8_144656219_144656478	0.30	RP11-661A12.9		688	0.35
chr11_65348415_65348566	0.30	EHBP1L1	EH domain binding protein 1-like 1	880	0.33
chr1_160371351_160371547	0.30	VANGL2	VANGL planar cell polarity protein 2	1073	0.41
chr10_112545701_112545852	0.29	ENSG00000199364	.	24876	0.15
chr1_11372585_11372736	0.29	UBIAD1	UbiA prenyltransferase domain containing 1	38669	0.14
chr10_74040371_74040522	0.29	RP11-442H21.2		4708	0.18
chr2_86103402_86103553	0.29	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	8700	0.2
chr1_108136425_108136722	0.29	VAV3	vav 3 guanine nucleotide exchange factor	94553	0.09
chr16_27296547_27296843	0.29	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	16580	0.16
chr22_31002849_31003013	0.29	PES1	pescadillo ribosomal biogenesis factor 1	44	0.5
chr2_20647758_20647971	0.29	RHOB	ras homolog family member B	1029	0.55
chr10_14634065_14634314	0.29	FAM107B	family with sequence similarity 107, member B	12199	0.23
chr12_4033133_4033294	0.29	RP11-664D1.1		18827	0.24
chr1_1983248_1983399	0.29	PRKCZ	protein kinase C, zeta	1076	0.37
chr17_76135260_76135499	0.29	TMC6	transmembrane channel-like 6	6891	0.11
chr16_84747666_84747817	0.29	USP10	ubiquitin specific peptidase 10	14095	0.21
chr11_62380549_62380700	0.28	ROM1	retinal outer segment membrane protein 1	377	0.4
chr20_44689713_44690123	0.28	NCOA5	nuclear receptor coactivator 5	28673	0.11
chr9_95534699_95534850	0.28	BICD2	bicaudal D homolog 2 (Drosophila)	7680	0.2
chr12_122230457_122230608	0.28	RHOF	ras homolog family member F (in filopodia)	734	0.62
chr20_60984429_60984580	0.28	CABLES2	Cdk5 and Abl enzyme substrate 2	2163	0.22
chr21_39862475_39862629	0.28	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	7793	0.32
chr15_48858312_48858463	0.28	FBN1	fibrillin 1	79531	0.1
chr10_28577623_28577798	0.28	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	6643	0.25
chr18_77937855_77938006	0.28	AC139100.3		3633	0.24
chr1_32682080_32682262	0.28	EIF3I	eukaryotic translation initiation factor 3, subunit I	5358	0.08
chr10_63945482_63945633	0.28	RTKN2	rhotekin 2	50465	0.15
chr16_88970888_88971039	0.28	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	2040	0.2
chr15_64340821_64340972	0.28	DAPK2	death-associated protein kinase 2	2375	0.29
chr20_44633733_44633884	0.28	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	3739	0.15
chr3_47029046_47029197	0.28	CCDC12	coiled-coil domain containing 12	5649	0.19
chr9_140603655_140603806	0.28	EHMT1	euchromatic histone-lysine N-methyltransferase 1	90276	0.06
chr9_38042649_38042933	0.28	SHB	Src homology 2 domain containing adaptor protein B	26417	0.21
chr1_209923175_209923334	0.28	TRAF3IP3	TRAF3 interacting protein 3	6123	0.15
chr19_10695511_10695662	0.28	AP1M2	adaptor-related protein complex 1, mu 2 subunit	2309	0.15
chr16_88433_88739	0.27	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)	14424	0.09
chr4_71704793_71704944	0.27	GRSF1	G-rich RNA sequence binding factor 1	150	0.94
chr12_54778620_54778771	0.27	ZNF385A	zinc finger protein 385A	188	0.89
chr6_167506513_167506813	0.27	CCR6	chemokine (C-C motif) receptor 6	18632	0.18
chr10_32585928_32586079	0.27	RP11-166N17.3		15389	0.15
chr12_95071507_95071838	0.27	TMCC3	transmembrane and coiled-coil domain family 3	27334	0.23
chr22_38294335_38294486	0.27	ENSG00000207227	.	7056	0.1
chr17_80011333_80011484	0.27	GPS1	G protein pathway suppressor 1	1299	0.19
chr15_55548229_55548380	0.27	RAB27A	RAB27A, member RAS oncogene family	7071	0.22
chr8_61598898_61599255	0.27	CHD7	chromodomain helicase DNA binding protein 7	6953	0.29
chr11_68115076_68115227	0.27	LRP5	low density lipoprotein receptor-related protein 5	35074	0.17
chr12_53747146_53747297	0.27	SP7	Sp7 transcription factor	8122	0.12
chr12_12002796_12002947	0.27	ETV6	ets variant 6	36000	0.22
chr4_40228763_40229105	0.27	RHOH	ras homolog family member H	26970	0.19
chr21_38073568_38073807	0.27	AP000697.6		177	0.94
chr9_130729734_130729885	0.27	FAM102A	family with sequence similarity 102, member A	12983	0.1
chr13_46424723_46424991	0.27	SIAH3	siah E3 ubiquitin protein ligase family member 3	1014	0.66
chr3_47412420_47412571	0.27	RP11-708J19.1		9994	0.17
chr3_57986357_57986508	0.26	FLNB	filamin B, beta	7695	0.27
chr1_154389484_154389635	0.26	RP11-350G8.5		10519	0.13
chr3_17780544_17780724	0.26	TBC1D5	TBC1 domain family, member 5	1765	0.51
chr22_24434829_24434980	0.26	CABIN1	calcineurin binding protein 1	27036	0.12
chr17_76137576_76137744	0.26	C17orf99	chromosome 17 open reading frame 99	4774	0.12
chr10_104945422_104945573	0.26	NT5C2	5'-nucleotidase, cytosolic II	7558	0.22
chr1_200984555_200984769	0.26	KIF21B	kinesin family member 21B	7874	0.19
chr20_57844261_57844469	0.26	EDN3	endothelin 3	31117	0.2
chr14_24634883_24635034	0.26	IRF9	interferon regulatory factor 9	2753	0.08
chr19_17956924_17957090	0.26	JAK3	Janus kinase 3	1751	0.23
chr8_24857635_24857890	0.26	CTD-2168K21.2		43627	0.16
chr22_45628414_45628565	0.26	KIAA0930	KIAA0930	3669	0.22
chr9_134130454_134130800	0.26	FAM78A	family with sequence similarity 78, member A	15253	0.16
chr11_1546577_1546728	0.26	MOB2	MOB kinase activator 2	38676	0.1
chr3_126203125_126203293	0.26	ZXDC	ZXD family zinc finger C	8447	0.17
chr17_48075656_48075807	0.26	DLX3	distal-less homeobox 3	3143	0.2
chr22_29198950_29199173	0.26	CTA-292E10.6		1181	0.37

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.3	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.3	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.1	GO:0098900	regulation of action potential(GO:0098900)
0.1	0.2	GO:0060214	endocardium formation(GO:0060214)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.3	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.2	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.1	0.3	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	0.4	GO:0045588	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1	0.1	GO:0060453	regulation of gastric acid secretion(GO:0060453)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1	0.2	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.2	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.2	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.3	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1	0.4	GO:0015884	folic acid transport(GO:0015884)
0.1	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.2	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:0060073	micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0043276	anoikis(GO:0043276)
0.0	0.2	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.3	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.2	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0070431	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.2	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.8	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) positive regulation of hypersensitivity(GO:0002885)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0045605	negative regulation of epidermal cell differentiation(GO:0045605)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.4	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0050685	regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.2	GO:0030540	female genitalia development(GO:0030540)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0070293	renal absorption(GO:0070293)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.0	0.0	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.5	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.1	GO:2000403	T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0	0.0	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:0046643	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.3	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.2	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.0	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468) regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:1902743	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0003159	morphogenesis of an endothelium(GO:0003159)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0014044	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.3	GO:0051693	actin filament capping(GO:0051693)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.2	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.2	GO:0051452	intracellular pH reduction(GO:0051452)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0071545	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548)
0.0	0.0	GO:0002524	hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.0	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.2	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0045851	pH reduction(GO:0045851)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.0	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.3	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0030837	negative regulation of actin filament polymerization(GO:0030837)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.0	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441) ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.2	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0035094	response to nicotine(GO:0035094)
0.0	0.1	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0060359	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) response to ammonium ion(GO:0060359) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.0	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0030593	neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0	0.0	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.0	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0006837	serotonin transport(GO:0006837)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0	0.1	GO:0032570	response to progesterone(GO:0032570)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.3	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.0	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.0	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:0045059	positive thymic T cell selection(GO:0045059)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.5	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.0	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.7	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.5	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.3	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.0	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.0	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.7	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.3	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.3	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.5	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0034617	nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.3	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0033265	cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0000977	transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.5	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.8	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	PID IGF1 PATHWAY	IGF1 pathway
0.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.0	REACTOME TRIF MEDIATED TLR3 SIGNALING	Genes involved in TRIF mediated TLR3 signaling
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA

Results for MAFA

Z-value: 1.72

Motif logo

Transcription factors associated with MAFA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MAFA motif across conditions

Conditions sorted by the z-value of the MAFA motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: