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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MAFA

Z-value: 1.72

Motif logo

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
ENSG00000182759.3 MAFA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MAFAchr8_144512410_144512561910.9461500.818.7e-03Click!
MAFAchr8_144511807_1445119586940.5417330.722.8e-02Click!
MAFAchr8_144513885_14451417914560.2717180.674.6e-02Click!
MAFAchr8_144510187_14451057121970.1858060.674.8e-02Click!
MAFAchr8_144517339_14451749048380.1263810.675.0e-02Click!

Activity of the MAFA motif across conditions

Conditions sorted by the z-value of the MAFA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr21_46955498_46955649 0.74 SLC19A1
solute carrier family 19 (folate transporter), member 1
1044
0.57
chr3_52140801_52140952 0.66 LINC00696
long intergenic non-protein coding RNA 696
43309
0.09
chr3_48263739_48263890 0.64 CAMP
cathelicidin antimicrobial peptide
1023
0.42
chr4_5054457_5054608 0.58 STK32B
serine/threonine kinase 32B
1363
0.53
chr3_127395993_127396144 0.51 ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
3115
0.23
chr22_39363886_39364037 0.50 APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
10434
0.12
chr2_95941719_95941977 0.50 PROM2
prominin 2
1603
0.42
chr9_137262651_137262802 0.49 ENSG00000263897
.
8531
0.25
chr1_3526502_3526724 0.49 MEGF6
multiple EGF-like-domains 6
1446
0.31
chr10_79397018_79397495 0.48 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
4
0.99
chr20_56888582_56888769 0.48 RAB22A
RAB22A, member RAS oncogene family
3923
0.23
chr11_47420144_47420472 0.48 ENSG00000264583
.
2213
0.15
chr16_89427857_89428160 0.47 ANKRD11
ankyrin repeat domain 11
32614
0.1
chr19_7401594_7401745 0.47 CTB-133G6.1

12179
0.16
chr7_150148399_150148619 0.46 GIMAP8
GTPase, IMAP family member 8
791
0.61
chr10_29971037_29971284 0.46 ENSG00000222092
.
29684
0.19
chr19_1240543_1240694 0.46 ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
1131
0.27
chr1_160905464_160905865 0.46 RP11-544M22.1

3409
0.18
chr1_44874319_44874616 0.46 RNF220
ring finger protein 220
3303
0.23
chr8_145520955_145521106 0.46 HSF1
heat shock transcription factor 1
4768
0.09
chr19_58324388_58324619 0.46 ZNF552
zinc finger protein 552
269
0.83
chr15_85264710_85265101 0.46 SEC11A
SEC11 homolog A (S. cerevisiae)
4958
0.15
chr17_55168522_55168933 0.45 AKAP1
A kinase (PRKA) anchor protein 1
4478
0.21
chr21_47059988_47060139 0.44 PCBP3
poly(rC) binding protein 3
3545
0.31
chr11_64629664_64630187 0.43 EHD1
EH-domain containing 1
13213
0.09
chr3_43257495_43257646 0.43 ENSG00000222331
.
5207
0.26
chr21_34764530_34764681 0.42 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
10597
0.18
chr6_116772160_116772456 0.42 ENSG00000265516
.
6677
0.14
chr17_29819355_29819635 0.42 RAB11FIP4
RAB11 family interacting protein 4 (class II)
4369
0.16
chr18_9850464_9850615 0.42 ENSG00000252680
.
5696
0.19
chr2_106475830_106476129 0.42 AC009505.2

2346
0.36
chr15_40550177_40550328 0.42 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
4867
0.11
chr2_37897671_37897822 0.42 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
1588
0.51
chr10_135092995_135093366 0.42 ADAM8
ADAM metallopeptidase domain 8
2808
0.14
chr22_37267478_37267629 0.41 NCF4
neutrophil cytosolic factor 4, 40kDa
626
0.53
chr18_72346363_72346608 0.41 ZNF407
zinc finger protein 407
3509
0.35
chr12_11939644_11939800 0.40 ETV6
ets variant 6
34287
0.22
chr11_121316146_121316378 0.40 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
6650
0.25
chr10_45920968_45921180 0.39 RP11-67C2.2

27495
0.19
chr10_73499250_73499401 0.39 C10orf105
chromosome 10 open reading frame 105
1744
0.38
chr1_43398187_43398359 0.39 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
1477
0.41
chr17_7976584_7976755 0.39 AC129492.6

6131
0.1
chr2_46635430_46635581 0.39 ENSG00000241791
.
40145
0.15
chr3_182928481_182928632 0.39 B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
42476
0.13
chr1_68026967_68027118 0.39 ENSG00000207504
.
20232
0.23
chr11_44600925_44601210 0.39 CD82
CD82 molecule
6439
0.22
chr20_1315455_1315606 0.39 AL136531.1
HCG2043693; Uncharacterized protein
2025
0.23
chrX_68505919_68506070 0.39 PJA1
praja ring finger 1, E3 ubiquitin protein ligase
120358
0.06
chr8_131000097_131000248 0.39 ENSG00000253043
.
16675
0.16
chr14_60337600_60337751 0.38 RTN1
reticulon 1
9
0.98
chr2_60727304_60727455 0.38 AC009970.1

4558
0.28
chr19_35756219_35756370 0.38 AD000684.2

2545
0.13
chr5_14178843_14178994 0.37 TRIO
trio Rho guanine nucleotide exchange factor
4989
0.36
chr15_52068308_52068538 0.37 CTD-2308G16.1

23741
0.12
chr11_46362037_46362188 0.37 DGKZ
diacylglycerol kinase, zeta
1964
0.27
chr19_54880893_54881262 0.37 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
981
0.39
chr2_121381891_121382042 0.36 ENSG00000201006
.
26883
0.24
chr2_127643425_127643576 0.36 AC114783.1
Protein LOC339760
12972
0.28
chr6_37023193_37023344 0.36 COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
10661
0.2
chr1_12211169_12211320 0.36 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
15816
0.15
chr17_74487092_74487507 0.36 RHBDF2
rhomboid 5 homolog 2 (Drosophila)
1937
0.2
chr1_153485547_153485698 0.36 ENSG00000263841
.
12382
0.09
chr12_102065427_102065608 0.36 RP11-755O11.2

11769
0.15
chr15_75641179_75641332 0.35 NEIL1
nei endonuclease VIII-like 1 (E. coli)
515
0.67
chr19_49931671_49931926 0.35 GFY
golgi-associated, olfactory signaling regulator
4792
0.07
chr4_169799427_169799622 0.35 ENSG00000201176
.
6982
0.22
chr20_62574273_62574438 0.35 ENSG00000207554
.
276
0.72
chr11_953594_953745 0.35 ENSG00000264671
.
2305
0.18
chr10_8103926_8104304 0.35 GATA3
GATA binding protein 3
7346
0.33
chr21_45876262_45876442 0.35 LRRC3
leucine rich repeat containing 3
983
0.28
chr5_176905874_176906027 0.35 DBN1
drebrin 1
4548
0.11
chr14_100072738_100072889 0.35 CCDC85C
coiled-coil domain containing 85C
2450
0.27
chr18_60799610_60799761 0.34 RP11-299P2.1

18868
0.23
chr4_38622899_38623179 0.34 RP11-617D20.1

3157
0.28
chr3_71752260_71752853 0.34 EIF4E3
eukaryotic translation initiation factor 4E family member 3
21970
0.2
chr17_4754312_4754498 0.34 MINK1
misshapen-like kinase 1
17526
0.08
chr21_16582150_16582301 0.34 NRIP1
nuclear receptor interacting protein 1
144904
0.05
chr1_209826804_209826967 0.34 LAMB3
laminin, beta 3
1074
0.44
chr11_110166518_110166669 0.34 RDX
radixin
744
0.8
chr4_143345126_143345417 0.33 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
7141
0.35
chr7_65445478_65445877 0.33 GUSB
glucuronidase, beta
1521
0.44
chr7_111825883_111826034 0.33 DOCK4
dedicator of cytokinesis 4
20492
0.21
chr14_24785019_24785170 0.33 LTB4R
leukotriene B4 receptor
1188
0.21
chr18_54492142_54492605 0.33 RP11-383D22.1

48828
0.14
chr3_134324324_134324540 0.33 EPHB1
EPH receptor B1
9775
0.22
chr17_55188705_55188891 0.33 AKAP1
A kinase (PRKA) anchor protein 1
3052
0.27
chr11_118958578_118958866 0.33 HMBS
hydroxymethylbilane synthase
25
0.93
chr4_183727825_183728099 0.33 ENSG00000221186
.
19419
0.21
chr20_37435383_37435534 0.33 PPP1R16B
protein phosphatase 1, regulatory subunit 16B
1091
0.52
chr11_128357006_128357190 0.33 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
18191
0.24
chr9_130616494_130616662 0.33 ENG
endoglin
337
0.74
chr11_133897961_133898138 0.33 JAM3
junctional adhesion molecule 3
40771
0.15
chr6_19838236_19838410 0.33 ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
706
0.56
chr13_41180871_41181022 0.33 FOXO1
forkhead box O1
59788
0.12
chr22_46543772_46543923 0.33 PPARA
peroxisome proliferator-activated receptor alpha
2577
0.2
chr3_183253186_183253337 0.33 KLHL6-AS1
KLHL6 antisense RNA 1
13262
0.16
chr1_35150748_35150899 0.32 ENSG00000207941
.
15528
0.19
chr10_80908302_80908453 0.32 ZMIZ1
zinc finger, MIZ-type containing 1
79585
0.1
chr19_51228108_51228259 0.32 CLEC11A
C-type lectin domain family 11, member A
1403
0.27
chr18_43923958_43924235 0.32 RNF165
ring finger protein 165
9909
0.28
chr22_45074770_45074921 0.32 PRR5
proline rich 5 (renal)
1880
0.36
chr17_76123196_76123347 0.32 TMC6
transmembrane channel-like 6
170
0.91
chr5_140934914_140935065 0.32 CTD-2024I7.13

2889
0.17
chr21_46346499_46346961 0.32 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
1903
0.19
chr6_170123147_170123298 0.31 PHF10
PHD finger protein 10
805
0.43
chr15_77286822_77287094 0.31 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
468
0.82
chr1_227747527_227747704 0.31 ENSG00000202264
.
1267
0.48
chr21_19148494_19148866 0.31 AL109761.5

17125
0.22
chr10_116259650_116260051 0.31 ABLIM1
actin binding LIM protein 1
12098
0.26
chr1_1832753_1832904 0.31 RP1-140A9.1

9918
0.12
chr4_7043959_7044306 0.31 TADA2B
transcriptional adaptor 2B
506
0.46
chr1_9686959_9687110 0.31 PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
24756
0.14
chr18_77559512_77559674 0.31 KCNG2
potassium voltage-gated channel, subfamily G, member 2
64075
0.12
chr9_71789095_71789246 0.31 TJP2
tight junction protein 2
23
0.99
chr22_37261033_37261184 0.31 NCF4
neutrophil cytosolic factor 4, 40kDa
4078
0.16
chr1_170634081_170634326 0.31 PRRX1
paired related homeobox 1
1125
0.64
chr19_42144649_42144840 0.30 CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
11302
0.14
chr2_31274988_31275144 0.30 ENSG00000216093
.
16647
0.23
chr1_205474854_205475005 0.30 CDK18
cyclin-dependent kinase 18
999
0.52
chr3_197465112_197465263 0.30 FYTTD1
forty-two-three domain containing 1
1137
0.38
chr8_33412460_33412753 0.30 RNF122
ring finger protein 122
12037
0.13
chr3_46278155_46278310 0.30 CCR3
chemokine (C-C motif) receptor 3
5640
0.23
chr22_46846609_46846760 0.30 CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1
84507
0.08
chr2_149634254_149634486 0.30 KIF5C
kinesin family member 5C
1551
0.38
chr11_118827290_118827441 0.30 UPK2
uroplakin 2
339
0.71
chr10_13837379_13837803 0.30 FRMD4A
FERM domain containing 4A
63321
0.09
chr14_91830928_91831128 0.30 ENSG00000265856
.
30971
0.18
chr17_76493340_76493491 0.30 DNAH17-AS1
DNAH17 antisense RNA 1
1496
0.34
chr20_62696555_62696706 0.30 TCEA2
transcription elongation factor A (SII), 2
934
0.36
chr20_44640102_44640397 0.30 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
2702
0.18
chr8_144656219_144656478 0.30 RP11-661A12.9

688
0.35
chr11_65348415_65348566 0.30 EHBP1L1
EH domain binding protein 1-like 1
880
0.33
chr1_160371351_160371547 0.30 VANGL2
VANGL planar cell polarity protein 2
1073
0.41
chr10_112545701_112545852 0.29 ENSG00000199364
.
24876
0.15
chr1_11372585_11372736 0.29 UBIAD1
UbiA prenyltransferase domain containing 1
38669
0.14
chr10_74040371_74040522 0.29 RP11-442H21.2

4708
0.18
chr2_86103402_86103553 0.29 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
8700
0.2
chr1_108136425_108136722 0.29 VAV3
vav 3 guanine nucleotide exchange factor
94553
0.09
chr16_27296547_27296843 0.29 NSMCE1
non-SMC element 1 homolog (S. cerevisiae)
16580
0.16
chr22_31002849_31003013 0.29 PES1
pescadillo ribosomal biogenesis factor 1
44
0.5
chr2_20647758_20647971 0.29 RHOB
ras homolog family member B
1029
0.55
chr10_14634065_14634314 0.29 FAM107B
family with sequence similarity 107, member B
12199
0.23
chr12_4033133_4033294 0.29 RP11-664D1.1

18827
0.24
chr1_1983248_1983399 0.29 PRKCZ
protein kinase C, zeta
1076
0.37
chr17_76135260_76135499 0.29 TMC6
transmembrane channel-like 6
6891
0.11
chr16_84747666_84747817 0.29 USP10
ubiquitin specific peptidase 10
14095
0.21
chr11_62380549_62380700 0.28 ROM1
retinal outer segment membrane protein 1
377
0.4
chr20_44689713_44690123 0.28 NCOA5
nuclear receptor coactivator 5
28673
0.11
chr9_95534699_95534850 0.28 BICD2
bicaudal D homolog 2 (Drosophila)
7680
0.2
chr12_122230457_122230608 0.28 RHOF
ras homolog family member F (in filopodia)
734
0.62
chr20_60984429_60984580 0.28 CABLES2
Cdk5 and Abl enzyme substrate 2
2163
0.22
chr21_39862475_39862629 0.28 ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
7793
0.32
chr15_48858312_48858463 0.28 FBN1
fibrillin 1
79531
0.1
chr10_28577623_28577798 0.28 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
6643
0.25
chr18_77937855_77938006 0.28 AC139100.3

3633
0.24
chr1_32682080_32682262 0.28 EIF3I
eukaryotic translation initiation factor 3, subunit I
5358
0.08
chr10_63945482_63945633 0.28 RTKN2
rhotekin 2
50465
0.15
chr16_88970888_88971039 0.28 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
2040
0.2
chr15_64340821_64340972 0.28 DAPK2
death-associated protein kinase 2
2375
0.29
chr20_44633733_44633884 0.28 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
3739
0.15
chr3_47029046_47029197 0.28 CCDC12
coiled-coil domain containing 12
5649
0.19
chr9_140603655_140603806 0.28 EHMT1
euchromatic histone-lysine N-methyltransferase 1
90276
0.06
chr9_38042649_38042933 0.28 SHB
Src homology 2 domain containing adaptor protein B
26417
0.21
chr1_209923175_209923334 0.28 TRAF3IP3
TRAF3 interacting protein 3
6123
0.15
chr19_10695511_10695662 0.28 AP1M2
adaptor-related protein complex 1, mu 2 subunit
2309
0.15
chr16_88433_88739 0.27 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
14424
0.09
chr4_71704793_71704944 0.27 GRSF1
G-rich RNA sequence binding factor 1
150
0.94
chr12_54778620_54778771 0.27 ZNF385A
zinc finger protein 385A
188
0.89
chr6_167506513_167506813 0.27 CCR6
chemokine (C-C motif) receptor 6
18632
0.18
chr10_32585928_32586079 0.27 RP11-166N17.3

15389
0.15
chr12_95071507_95071838 0.27 TMCC3
transmembrane and coiled-coil domain family 3
27334
0.23
chr22_38294335_38294486 0.27 ENSG00000207227
.
7056
0.1
chr17_80011333_80011484 0.27 GPS1
G protein pathway suppressor 1
1299
0.19
chr15_55548229_55548380 0.27 RAB27A
RAB27A, member RAS oncogene family
7071
0.22
chr8_61598898_61599255 0.27 CHD7
chromodomain helicase DNA binding protein 7
6953
0.29
chr11_68115076_68115227 0.27 LRP5
low density lipoprotein receptor-related protein 5
35074
0.17
chr12_53747146_53747297 0.27 SP7
Sp7 transcription factor
8122
0.12
chr12_12002796_12002947 0.27 ETV6
ets variant 6
36000
0.22
chr4_40228763_40229105 0.27 RHOH
ras homolog family member H
26970
0.19
chr21_38073568_38073807 0.27 AP000697.6

177
0.94
chr9_130729734_130729885 0.27 FAM102A
family with sequence similarity 102, member A
12983
0.1
chr13_46424723_46424991 0.27 SIAH3
siah E3 ubiquitin protein ligase family member 3
1014
0.66
chr3_47412420_47412571 0.27 RP11-708J19.1

9994
0.17
chr3_57986357_57986508 0.26 FLNB
filamin B, beta
7695
0.27
chr1_154389484_154389635 0.26 RP11-350G8.5

10519
0.13
chr3_17780544_17780724 0.26 TBC1D5
TBC1 domain family, member 5
1765
0.51
chr22_24434829_24434980 0.26 CABIN1
calcineurin binding protein 1
27036
0.12
chr17_76137576_76137744 0.26 C17orf99
chromosome 17 open reading frame 99
4774
0.12
chr10_104945422_104945573 0.26 NT5C2
5'-nucleotidase, cytosolic II
7558
0.22
chr1_200984555_200984769 0.26 KIF21B
kinesin family member 21B
7874
0.19
chr20_57844261_57844469 0.26 EDN3
endothelin 3
31117
0.2
chr14_24634883_24635034 0.26 IRF9
interferon regulatory factor 9
2753
0.08
chr19_17956924_17957090 0.26 JAK3
Janus kinase 3
1751
0.23
chr8_24857635_24857890 0.26 CTD-2168K21.2

43627
0.16
chr22_45628414_45628565 0.26 KIAA0930
KIAA0930
3669
0.22
chr9_134130454_134130800 0.26 FAM78A
family with sequence similarity 78, member A
15253
0.16
chr11_1546577_1546728 0.26 MOB2
MOB kinase activator 2
38676
0.1
chr3_126203125_126203293 0.26 ZXDC
ZXD family zinc finger C
8447
0.17
chr17_48075656_48075807 0.26 DLX3
distal-less homeobox 3
3143
0.2
chr22_29198950_29199173 0.26 CTA-292E10.6

1181
0.37

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.3 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.1 0.1 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.2 GO:0060214 endocardium formation(GO:0060214)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.3 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1 0.1 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.1 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1 0.2 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.2 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.1 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.4 GO:0015884 folic acid transport(GO:0015884)
0.1 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0060073 micturition(GO:0060073) synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0043276 anoikis(GO:0043276)
0.0 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.3 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0070431 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) positive regulation of hypersensitivity(GO:0002885)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0050685 regulation of mRNA 3'-end processing(GO:0031440) positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.2 GO:0030540 female genitalia development(GO:0030540)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.0 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:2000403 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0 0.0 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0032661 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:1902743 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0003159 morphogenesis of an endothelium(GO:0003159)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:0014044 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.0 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.0 GO:0002524 hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.0 0.3 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0045851 pH reduction(GO:0045851)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0006026 aminoglycan catabolic process(GO:0006026)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.0 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:1902692 regulation of neuroblast proliferation(GO:1902692)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.0 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441) ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.2 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0060359 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) response to ammonium ion(GO:0060359) cellular response to ammonium ion(GO:0071242) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.0 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.0 GO:0002327 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0006837 serotonin transport(GO:0006837)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.1 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.0 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.3 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.0 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0045059 positive thymic T cell selection(GO:0045059)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 0.0 GO:0001520 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.0 GO:0030686 90S preribosome(GO:0030686)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0033265 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0000977 transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.0 REACTOME TRIF MEDIATED TLR3 SIGNALING Genes involved in TRIF mediated TLR3 signaling
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA