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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MBD2

Z-value: 0.83

Motif logo

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr18_51750110_51750261MBD28020.5546680.761.7e-02Click!
chr18_51749861_51750099MBD210070.4309760.655.6e-02Click!
chr18_51765765_51765916MBD2146820.1868360.541.4e-01Click!
chr18_51766674_51767013MBD2156850.1846180.363.4e-01Click!
chr18_51765483_51765634MBD2144000.1874600.343.7e-01Click!

Activity of the MBD2 motif across conditions

Conditions sorted by the z-value of the MBD2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_158525970_158526185 0.23 EBF1
 early B-cell factor 1
 624
 0.8
chr17_4047225_4047376 0.23 CYB5D2
 cytochrome b5 domain containing 2
 304
 0.77
chr2_227664099_227664289 0.20 IRS1
 insulin receptor substrate 1
 281
 0.92
chr1_36923322_36923556 0.20 MRPS15
 mitochondrial ribosomal protein S15
 6599
 0.14
chr2_28616465_28616616 0.20 FOSL2
 FOS-like antigen 2
 815
 0.43
chr12_106641074_106641225 0.20 RP11-651L5.2
415
 0.6
chr4_129731338_129731616 0.19 JADE1
 jade family PHD finger 1
 291
 0.94
chr1_200962213_200962376 0.19 KIF21B
 kinesin family member 21B
 30242
 0.15
chr1_28586799_28587133 0.18 SESN2
 sestrin 2
 928
 0.45
chr3_55521069_55521220 0.18 WNT5A
 wingless-type MMTV integration site family, member 5A
 187
 0.84
chr19_47222599_47222782 0.17 PRKD2
 protein kinase D2
 2306
 0.14
chr4_77871771_77872019 0.17 SEPT11
 septin 11
 880
 0.67
chr14_67826123_67826274 0.17 ATP6V1D
 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
 306
 0.65
chr15_40211997_40212191 0.17 GPR176
 G protein-coupled receptor 176
 332
 0.85
chr10_70320624_70320793 0.17 TET1
 tet methylcytosine dioxygenase 1
 295
 0.9
chr6_70576954_70577105 0.16 COL19A1
 collagen, type XIX, alpha 1
 566
 0.85
chr11_62313253_62313404 0.16 RP11-864I4.4
143
 0.52
chr12_57483024_57483175 0.16 NAB2
 NGFI-A binding protein 2 (EGR1 binding protein 2)
 209
 0.88
chr7_139875650_139875801 0.16 KDM7A
 lysine (K)-specific demethylase 7A
 1016
 0.41
chr8_49833855_49834028 0.15 SNAI2
 snail family zinc finger 2
 47
 0.99
chr9_131182814_131182965 0.15 CERCAM
 cerebral endothelial cell adhesion molecule
 129
 0.93
chr9_114659468_114659619 0.15 UGCG
 UDP-glucose ceramide glucosyltransferase
 497
 0.81
chr17_76129423_76129727 0.15 TMC6
 transmembrane channel-like 6
 1087
 0.35
chr2_71693709_71693860 0.15 DYSF
 dysferlin
 48
 0.98
chr5_87564263_87564414 0.14 TMEM161B
 transmembrane protein 161B
 301
 0.56
chr10_126107594_126107745 0.14 OAT
 ornithine aminotransferase
 124
 0.96
chr14_61124038_61124189 0.14 SIX1
 SIX homeobox 1
 864
 0.65
chr14_50778528_50778679 0.14 L2HGDH
 L-2-hydroxyglutarate dehydrogenase
 269
 0.65
chr1_169075983_169076134 0.14 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 497
 0.77
chr3_52739027_52739199 0.14 SPCS1
 signal peptidase complex subunit 1 homolog (S. cerevisiae)
 142
 0.81
chr6_139308621_139308772 0.14 REPS1
 RALBP1 associated Eps domain containing 1
 81
 0.98
chr17_1552892_1553043 0.14 RILP
 Rab interacting lysosomal protein
 404
 0.69
chr6_36646575_36646743 0.14 CDKN1A
 cyclin-dependent kinase inhibitor 1A (p21, Cip1)
 161
 0.94
chr5_175665590_175665741 0.14 SIMC1
 SUMO-interacting motifs containing 1
 262
 0.93
chr12_15941961_15942112 0.14 EPS8
 epidermal growth factor receptor pathway substrate 8
 279
 0.95
chr3_62304846_62304997 0.14 C3orf14
 chromosome 3 open reading frame 14
 203
 0.62
chr18_59561361_59561512 0.13 RNF152
 ring finger protein 152
 28
 0.99
chr2_37898161_37898436 0.13 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 1036
 0.66
chr3_149689144_149689375 0.13 AC117395.1
 LOC646903 protein; Uncharacterized protein
 193
 0.57
chr8_144329183_144329334 0.13 ZFP41
22
 0.96
chr7_42276182_42276486 0.13 GLI3
 GLI family zinc finger 3
 278
 0.96
chr17_48133834_48134023 0.13 ITGA3
 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
 124
 0.95
chr17_8025338_8025489 0.13 HES7
 hes family bHLH transcription factor 7
 1989
 0.15
chr10_12390683_12390842 0.13 CAMK1D
 calcium/calmodulin-dependent protein kinase ID
 719
 0.67
chr10_96162263_96162513 0.13 TBC1D12
 TBC1 domain family, member 12
 127
 0.97
chr13_95254337_95254566 0.13 GPR180
 G protein-coupled receptor 180
 294
 0.91
chr22_38349909_38350064 0.13 POLR2F
 polymerase (RNA) II (DNA directed) polypeptide F
 252
 0.53
chr7_99097504_99097655 0.12 ZNF394
 zinc finger protein 394
 308
 0.8
chr1_44878601_44878847 0.12 RNF220
 ring finger protein 220
 954
 0.56
chr13_37493848_37494116 0.12 SMAD9
 SMAD family member 9
 393
 0.88
chr1_17764676_17764827 0.12 RCC2
 regulator of chromosome condensation 2
 306
 0.88
chr9_139895229_139895380 0.12 CLIC3
 chloride intracellular channel 3
 4049
 0.07
chr16_88533909_88534060 0.12 ENSG00000263456
 .
 1342
 0.4
chr12_124155798_124155949 0.12 TCTN2
 tectonic family member 2
 213
 0.91
chr8_61564342_61564493 0.12 CHD7
 chromodomain helicase DNA binding protein 7
 26920
 0.22
chr17_75842366_75842622 0.12 FLJ45079
36165
 0.19
chr2_97535201_97535472 0.12 SEMA4C
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
 372
 0.81
chr3_118959156_118959307 0.12 B4GALT4
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
 227
 0.92
chr11_73716058_73716371 0.12 UCP3
 uncoupling protein 3 (mitochondrial, proton carrier)
 2135
 0.25
chr12_66219604_66219755 0.12 HMGA2
 high mobility group AT-hook 2
 776
 0.69
chr8_128806386_128806537 0.12 ENSG00000249859
 .
 1747
 0.46
chr20_50721480_50721631 0.12 ZFP64
 ZFP64 zinc finger protein
 93
 0.98
chr17_73149465_73149616 0.11 HN1
 hematological and neurological expressed 1
 152
 0.9
chr2_232329699_232329872 0.11 NCL
 nucleolin
 480
 0.67
chr6_3157928_3158079 0.11 TUBB2A
 tubulin, beta 2A class IIa
 243
 0.9
chr2_12627750_12628043 0.11 ENSG00000207183
 .
 76269
 0.12
chr1_12206631_12206794 0.11 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 20348
 0.14
chr1_117113459_117113610 0.11 CD58
 CD58 molecule
 114
 0.96
chr16_1664631_1664782 0.11 CRAMP1L
 Crm, cramped-like (Drosophila)
 65
 0.94
chr17_72920305_72920516 0.11 OTOP2
 otopetrin 2
 40
 0.93
chr8_143592312_143592463 0.11 BAI1
 brain-specific angiogenesis inhibitor 1
 47010
 0.13
chr14_105531218_105531594 0.11 GPR132
 G protein-coupled receptor 132
 361
 0.87
chr11_27721665_27721841 0.11 BDNF
 brain-derived neurotrophic factor
 282
 0.94
chr1_247267190_247267341 0.11 ZNF669
 zinc finger protein 669
 315
 0.87
chr1_204253357_204253508 0.11 RP11-203F10.5
7299
 0.2
chr22_50625070_50625221 0.11 TRABD
 TraB domain containing
 799
 0.4
chr15_70755158_70755354 0.11 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 239364
 0.02
chr7_2079893_2080044 0.11 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 39680
 0.19
chr17_17307764_17307974 0.11 ENSG00000201741
 .
 55889
 0.1
chr16_23860249_23860431 0.11 PRKCB
 protein kinase C, beta
 11796
 0.24
chr9_4297910_4298061 0.11 GLIS3
 GLIS family zinc finger 3
 511
 0.74
chr8_142427631_142427782 0.11 PTP4A3
 protein tyrosine phosphatase type IVA, member 3
 4301
 0.15
chr4_174255283_174255434 0.11 HMGB2
 high mobility group box 2
 42
 0.97
chr2_45236571_45236881 0.11 SIX2
 SIX homeobox 2
 157
 0.97
chr17_42298747_42298947 0.11 RP5-882C2.2
78
 0.58
chr16_29164996_29165147 0.11 CTB-134H23.3
46305
 0.11
chr5_98109480_98109631 0.10 RGMB
 repulsive guidance molecule family member b
 216
 0.69
chr1_9242870_9243036 0.10 ENSG00000207865
 .
 31117
 0.15
chr1_221174763_221174914 0.10 HLX
 H2.0-like homeobox
 120254
 0.06
chr10_88516958_88517218 0.10 BMPR1A
 bone morphogenetic protein receptor, type IA
 681
 0.52
chr10_3109354_3109505 0.10 PFKP
 phosphofructokinase, platelet
 283
 0.94
chr7_139875894_139876045 0.10 KDM7A
 lysine (K)-specific demethylase 7A
 772
 0.49
chr17_27169488_27169639 0.10 FAM222B
 family with sequence similarity 222, member B
 182
 0.87
chr7_130418710_130418861 0.10 KLF14
 Kruppel-like factor 14
 103
 0.97
chr6_166854947_166855218 0.10 RPS6KA2-IT1
 RPS6KA2 intronic transcript 1 (non-protein coding)
 23789
 0.17
chr1_840236_840387 0.10 SAMD11
 sterile alpha motif domain containing 11
 19949
 0.1
chr11_63535181_63535583 0.10 ENSG00000264519
 .
 30161
 0.13
chr19_46102764_46102973 0.10 GPR4
 G protein-coupled receptor 4
 2598
 0.14
chr10_129845544_129845695 0.10 PTPRE
 protein tyrosine phosphatase, receptor type, E
 51
 0.99
chr3_9885266_9885439 0.10 RPUSD3
 RNA pseudouridylate synthase domain containing 3
 274
 0.82
chr8_27491503_27491654 0.10 SCARA3
 scavenger receptor class A, member 3
 120
 0.96
chr3_192635854_192636005 0.10 MB21D2
 Mab-21 domain containing 2
 21
 0.99
chr19_2841960_2842118 0.10 ZNF555
 zinc finger protein 555
 597
 0.58
chr3_39425233_39425481 0.10 SLC25A38
 solute carrier family 25, member 38
 477
 0.75
chr11_57405830_57405981 0.10 AP000662.4
56
 0.95
chr7_40174611_40174762 0.10 SUGCT
 succinylCoA:glutarate-CoA transferase
 67
 0.86
chr12_49760368_49760519 0.10 SPATS2
 spermatogenesis associated, serine-rich 2
 76
 0.96
chr17_79361175_79361326 0.10 RP11-1055B8.6
 Uncharacterized protein
 8025
 0.12
chr2_239335294_239335445 0.10 ASB1
 ankyrin repeat and SOCS box containing 1
 96
 0.94
chr12_115121630_115121887 0.10 TBX3
 T-box 3
 211
 0.95
chr7_135347682_135347918 0.10 C7orf73
 chromosome 7 open reading frame 73
 531
 0.73
chr10_119135171_119135322 0.09 PDZD8
 PDZ domain containing 8
 268
 0.93
chr6_34112547_34112722 0.09 GRM4
 glutamate receptor, metabotropic 4
 1223
 0.55
chr1_228401023_228401174 0.09 C1orf145
 chromosome 1 open reading frame 145
 263
 0.87
chr13_113344676_113344827 0.09 ATP11A
 ATPase, class VI, type 11A
 108
 0.97
chr1_45808097_45808295 0.09 MUTYH
 mutY homolog
 2054
 0.23
chr7_43909566_43909799 0.09 MRPS24
 mitochondrial ribosomal protein S24
 526
 0.74
chr13_50017891_50018071 0.09 CAB39L
 calcium binding protein 39-like
 208
 0.73
chr8_67581847_67582257 0.09 C8orf44
 chromosome 8 open reading frame 44
 2165
 0.2
chr8_79578462_79578613 0.09 ZC2HC1A
 zinc finger, C2HC-type containing 1A
 255
 0.94
chr4_140477398_140477823 0.09 SETD7
 SET domain containing (lysine methyltransferase) 7
 218
 0.64
chr7_79764645_79764797 0.09 GNAI1
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
 116
 0.98
chr12_113314531_113314682 0.09 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
 29976
 0.16
chrX_39864924_39865126 0.09 BCOR
 BCL6 corepressor
 57165
 0.16
chr4_140098673_140098889 0.09 ELF2
 E74-like factor 2 (ets domain transcription factor)
 409
 0.8
chr17_71188126_71188355 0.09 COG1
 component of oligomeric golgi complex 1
 889
 0.54
chr17_36811230_36811381 0.09 C17orf96
 chromosome 17 open reading frame 96
 19882
 0.09
chr20_61604608_61604759 0.09 SLC17A9
 solute carrier family 17 (vesicular nucleotide transporter), member 9
 20285
 0.14
chr17_79849821_79850029 0.09 ANAPC11
 anaphase promoting complex subunit 11
 14
 0.85
chr2_27580084_27580240 0.09 AC074117.10
107
 0.72
chr17_3814962_3815143 0.09 P2RX1
 purinergic receptor P2X, ligand-gated ion channel, 1
 4742
 0.18
chr15_31619854_31620040 0.09 KLF13
 Kruppel-like factor 13
 889
 0.73
chr3_57581237_57581439 0.09 ARF4
 ADP-ribosylation factor 4
 1714
 0.21
chr13_42622874_42623025 0.09 DGKH
 diacylglycerol kinase, eta
 60
 0.98
chr6_21598054_21598402 0.09 SOX4
 SRY (sex determining region Y)-box 4
 4157
 0.38
chr12_42982787_42982938 0.09 PRICKLE1
 prickle homolog 1 (Drosophila)
 616
 0.82
chr19_695715_695866 0.09 PRSS57
 protease, serine, 57
 330
 0.79
chr22_37628846_37629004 0.09 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 11363
 0.13
chr17_27920798_27921030 0.09 GIT1
 G protein-coupled receptor kinase interacting ArfGAP 1
 158
 0.73
chr9_133814267_133814515 0.09 FIBCD1
 fibrinogen C domain containing 1
 64
 0.97
chr1_45008474_45008671 0.09 ENSG00000263381
 .
 2593
 0.31
chr1_190448073_190448224 0.09 BRINP3
 bone morphogenetic protein/retinoic acid inducible neural-specific 3
 1389
 0.62
chr21_47790160_47790311 0.09 PCNT
 pericentrin
 46199
 0.1
chr20_3073916_3074245 0.09 ENSG00000263905
 .
 781
 0.5
chr3_193721076_193721316 0.09 RP11-135A1.2
127794
 0.05
chr10_105110241_105110401 0.09 PCGF6
 polycomb group ring finger 6
 515
 0.7
chr7_150757151_150757478 0.09 SLC4A2
 solute carrier family 4 (anion exchanger), member 2
 157
 0.88
chr4_109089309_109089460 0.09 LEF1
 lymphoid enhancer-binding factor 1
 194
 0.86
chr1_115212366_115212517 0.09 DENND2C
 DENN/MADD domain containing 2C
 215
 0.92
chr8_8243228_8243507 0.09 SGK223
 Tyrosine-protein kinase SgK223
 641
 0.8
chr2_8534822_8535050 0.08 AC011747.7
280960
 0.01
chr4_174292034_174292185 0.08 SAP30
 Sin3A-associated protein, 30kDa
 15
 0.9
chr5_177580113_177580362 0.08 NHP2
 NHP2 ribonucleoprotein
 343
 0.87
chr5_74907731_74907925 0.08 ANKDD1B
 ankyrin repeat and death domain containing 1B
 544
 0.77
chr3_142682236_142682387 0.08 PAQR9
 progestin and adipoQ receptor family member IX
 133
 0.82
chr17_43226535_43226808 0.08 HEXIM1
 hexamethylene bis-acetamide inducible 1
 1987
 0.18
chr19_47231631_47231782 0.08 CTB-174O21.2
154
 0.78
chr3_55522055_55522206 0.08 WNT5A-AS1
 WNT5A antisense RNA 1
 403
 0.72
chr9_132312469_132312650 0.08 RP11-492E3.2
25129
 0.14
chr5_133984728_133984879 0.08 SAR1B
 SAR1 homolog B (S. cerevisiae)
 158
 0.66
chr17_44271140_44271291 0.08 KANSL1
 KAT8 regulatory NSL complex subunit 1
 30
 0.73
chr5_57755480_57755679 0.08 PLK2
 polo-like kinase 2
 508
 0.83
chr5_39424907_39425058 0.08 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 12
 0.99
chr1_151131154_151131481 0.08 SCNM1
 sodium channel modifier 1
 2177
 0.13
chr15_70767188_70767491 0.08 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 227281
 0.02
chr9_130742404_130742642 0.08 FAM102A
 family with sequence similarity 102, member A
 269
 0.86
chr11_72301686_72301842 0.08 PDE2A
 phosphodiesterase 2A, cGMP-stimulated
 301
 0.86
chr11_10328178_10328394 0.08 ADM
 adrenomedullin
 1362
 0.36
chr1_86046251_86046504 0.08 CYR61
 cysteine-rich, angiogenic inducer, 61
 67
 0.97
chr7_140773539_140773706 0.08 TMEM178B
 transmembrane protein 178B
 410
 0.87
chr11_74460077_74460228 0.08 RNF169
 ring finger protein 169
 239
 0.89
chr20_633536_633687 0.08 SRXN1
 sulfiredoxin 1
 403
 0.83
chr6_150263305_150263552 0.08 ULBP2
 UL16 binding protein 2
 292
 0.86
chr5_16935760_16935953 0.08 MYO10
 myosin X
 191
 0.95
chr5_64776318_64776785 0.08 ADAMTS6
 ADAM metallopeptidase with thrombospondin type 1 motif, 6
 1153
 0.57
chr12_9949678_9949885 0.08 KLRF1
 killer cell lectin-like receptor subfamily F, member 1
 30296
 0.12
chr2_8451327_8451593 0.08 AC011747.7
364436
 0.01
chr14_89020572_89020999 0.08 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 292
 0.87
chr1_25756426_25756577 0.08 RHCE
 Rh blood group, CcEe antigens
 182
 0.88
chr5_2739627_2739778 0.08 IRX2
 iroquois homeobox 2
 12067
 0.25
chr7_27162967_27163166 0.08 HOXA-AS2
 HOXA cluster antisense RNA 2
 279
 0.75
chr3_27524774_27525101 0.08 SLC4A7
 solute carrier family 4, sodium bicarbonate cotransporter, member 7
 901
 0.62
chr5_1495230_1495381 0.08 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 28787
 0.18
chr4_183839114_183839265 0.08 DCTD
 dCMP deaminase
 100
 0.98
chr1_25466873_25467076 0.08 RP4-706G24.1
67656
 0.1
chr21_45209574_45209725 0.08 RRP1
 ribosomal RNA processing 1
 255
 0.9
chr11_61596533_61596684 0.08 FADS1
 fatty acid desaturase 1
 173
 0.86
chr18_60903891_60904042 0.08 ENSG00000238988
 .
 42068
 0.15
chrX_9983834_9983985 0.08 WWC3
 WWC family member 3
 307
 0.9
chr3_150263594_150263745 0.08 SERP1
 stress-associated endoplasmic reticulum protein 1
 617
 0.53
chr3_42814583_42814734 0.08 CCDC13
 coiled-coil domain containing 13
 87
 0.94
chr1_183604255_183604406 0.08 ARPC5
 actin related protein 2/3 complex, subunit 5, 16kDa
 487
 0.63
chr4_77342405_77342556 0.08 SHROOM3
 shroom family member 3
 13773
 0.15
chr14_55033500_55033670 0.08 SAMD4A
 sterile alpha motif domain containing 4A
 230
 0.95
chr19_4809653_4809804 0.08 AC005523.2
14157
 0.1
chr14_58618488_58618681 0.08 C14orf37
 chromosome 14 open reading frame 37
 347
 0.88
chr21_47600208_47600359 0.08 SPATC1L
 spermatogenesis and centriole associated 1-like
 4090
 0.11
chr9_114361618_114361849 0.08 PTGR1
 prostaglandin reductase 1
 46
 0.97
chr7_50256424_50256575 0.08 AC020743.2
74080
 0.1
chr20_19997607_19997892 0.08 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 11
 0.98

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0072273 metanephric nephron morphogenesis(GO:0072273)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:2000095 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0046398 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling