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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MEF2B

Z-value: 1.10

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Transcription factors associated with MEF2B

Gene Symbol	Gene ID	Gene Info
MEF2B Ensembl NCBI GeneCards UniProt	ENSG00000213999.11	MEF2B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MEF2B	chr19_19271531_19271682	9448	0.106236	0.79	1.2e-02	Click!
MEF2B	chr19_19266537_19266688	14442	0.102133	0.74	2.4e-02	Click!
MEF2B	chr19_19270273_19270424	10706	0.105019	0.52	1.5e-01	Click!
MEF2B	chr19_19282891_19283042	1868	0.198439	0.51	1.6e-01	Click!
MEF2B	chr19_19271102_19271312	9847	0.105821	0.46	2.1e-01	Click!

Activity of the MEF2B motif across conditions

Conditions sorted by the z-value of the MEF2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_83043773_83044235	0.62	LPHN2	latrophilin 2	598431	0.0
chr10_114786502_114786745	0.57	RP11-57H14.2		74989	0.11
chr6_85293592_85293821	0.57	RP11-132M7.3		105437	0.08
chr3_177053679_177054041	0.55	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	138599	0.05
chr13_101149154_101149445	0.53	PCCA-AS1	PCCA antisense RNA 1	15888	0.18
chr20_23132592_23133523	0.51	ENSG00000201527	.	8551	0.22
chr13_30627332_30627483	0.50	LINC00572	long intergenic non-protein coding RNA 572	126619	0.06
chr6_114130369_114130564	0.50	ENSG00000253091	.	27799	0.16
chr6_25179466_25179765	0.48	ENSG00000222373	.	13026	0.19
chr1_168467710_168467921	0.48	XCL2	chemokine (C motif) ligand 2	45420	0.16
chr3_63908528_63908748	0.48	ATXN7	ataxin 7	10363	0.18
chr4_86747445_86747851	0.47	ARHGAP24	Rho GTPase activating protein 24	1250	0.59
chr1_184476924_184477075	0.46	GS1-115G20.1		99528	0.07
chr5_148796784_148796935	0.46	ENSG00000208035	.	11622	0.13
chr1_50575855_50576371	0.45	ELAVL4	ELAV like neuron-specific RNA binding protein 4	735	0.74
chr14_56777353_56777504	0.43	TMEM260	transmembrane protein 260	177644	0.03
chr1_61299199_61299350	0.41	NFIA	nuclear factor I/A	31657	0.24
chr5_124237918_124238155	0.41	ZNF608	zinc finger protein 608	153536	0.04
chr1_234656705_234656856	0.41	TARBP1	TAR (HIV-1) RNA binding protein 1	41931	0.14
chr3_48597793_48598316	0.40	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	508	0.63
chr2_173258743_173259031	0.40	ITGA6	integrin, alpha 6	33195	0.16
chr16_73200279_73201088	0.40	C16orf47	chromosome 16 open reading frame 47	22337	0.26
chr11_69264083_69264234	0.40	CCND1	cyclin D1	191697	0.03
chr15_42651493_42651677	0.40	CAPN3	calpain 3, (p94)	198	0.94
chr6_37519897_37520048	0.40	ENSG00000263926	.	3226	0.29
chr16_75086975_75087126	0.39	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	50855	0.11
chr20_3358805_3359063	0.38	ENSG00000201346	.	5942	0.16
chr8_17547050_17547201	0.37	ENSG00000265520	.	7959	0.17
chr2_208896310_208896486	0.37	PLEKHM3	pleckstrin homology domain containing, family M, member 3	6114	0.15
chr21_39193991_39194257	0.37	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	91433	0.08
chr8_120627310_120627516	0.36	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	22165	0.24
chr8_108316239_108316473	0.36	ANGPT1	angiopoietin 1	32394	0.22
chr2_158697443_158697594	0.35	ACVR1	activin A receptor, type I	2679	0.28
chr12_3764521_3764672	0.35	EFCAB4B	EF-hand calcium binding domain 4B	1207	0.6
chr5_75367452_75367603	0.35	SV2C	synaptic vesicle glycoprotein 2C	11470	0.24
chr14_105721504_105721672	0.35	BRF1	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	5847	0.17
chr17_6503024_6503317	0.35	ENSG00000200914	.	1201	0.36
chr11_124595331_124595482	0.35	NRGN	neurogranin (protein kinase C substrate, RC3)	14336	0.1
chr14_39317605_39317829	0.34	ENSG00000199285	.	138768	0.05
chr8_97803430_97803993	0.34	CPQ	carboxypeptidase Q	30243	0.25
chr17_66315705_66315870	0.34	ARSG	arylsulfatase G	28128	0.15
chr1_157745151_157745302	0.34	FCRL2	Fc receptor-like 2	1683	0.39
chr15_39850731_39850882	0.33	THBS1	thrombospondin 1	22474	0.19
chr12_12032698_12032849	0.33	ETV6	ets variant 6	6098	0.32
chr1_68056079_68056230	0.33	ENSG00000207504	.	49344	0.14
chr9_101803098_101803249	0.33	TGFBR1	transforming growth factor, beta receptor 1	63147	0.11
chr2_113429205_113429356	0.33	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	24001	0.17
chr12_15842783_15842934	0.32	ENSG00000200105	.	18114	0.22
chr7_29283267_29283581	0.32	AC004593.3		34838	0.16
chr2_202819063_202819214	0.32	ENSG00000221489	.	1079	0.52
chr2_43443107_43443258	0.32	ZFP36L2	ZFP36 ring finger protein-like 2	10566	0.23
chr22_27714638_27714789	0.32	ENSG00000200443	.	282863	0.01
chr16_84413717_84413987	0.31	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	11719	0.19
chr5_75722311_75722532	0.31	IQGAP2	IQ motif containing GTPase activating protein 2	22172	0.25
chr3_171038529_171038680	0.31	TNIK	TRAF2 and NCK interacting kinase	95104	0.08
chr5_74615457_74615613	0.31	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	16619	0.19
chr2_155312519_155312670	0.31	AC009227.2		1356	0.52
chr4_88832400_88832551	0.31	SPP1	secreted phosphoprotein 1	64344	0.1
chr7_129630529_129630680	0.31	ENSG00000263557	.	5017	0.14
chr11_34469686_34469883	0.31	CAT	catalase	9312	0.22
chr16_46689835_46690025	0.30	RP11-93O14.2		5573	0.18
chr1_235051769_235052023	0.30	ENSG00000239690	.	11963	0.27
chr12_11932326_11932519	0.30	ETV6	ets variant 6	26987	0.25
chr14_85775279_85775646	0.30	ENSG00000252529	.	37186	0.24
chr3_149160811_149161262	0.30	TM4SF4	transmembrane 4 L six family member 4	30725	0.16
chr20_17649733_17649884	0.30	RRBP1	ribosome binding protein 1	8656	0.21
chr19_19245450_19245992	0.30	TMEM161A	transmembrane protein 161A	2511	0.19
chr3_148477195_148477534	0.30	AGTR1	angiotensin II receptor, type 1	19779	0.22
chr9_124123057_124123675	0.30	STOM	stomatin	9117	0.15
chr12_49626641_49626792	0.30	TUBA1C	tubulin, alpha 1c	5007	0.14
chr2_55345739_55346346	0.29	RTN4	reticulon 4	6285	0.2
chr13_91415783_91415934	0.29	ENSG00000251753	.	18265	0.31
chr14_73881705_73881856	0.29	NUMB	numb homolog (Drosophila)	5001	0.21
chr2_218766852_218767096	0.29	TNS1	tensin 1	242	0.95
chr3_140795767_140796225	0.29	SPSB4	splA/ryanodine receptor domain and SOCS box containing 4	25752	0.2
chr12_392843_392994	0.29	RP11-283I3.6		6629	0.16
chr7_70907526_70907677	0.29	ENSG00000266688	.	132064	0.05
chr14_56683663_56683814	0.29	PELI2	pellino E3 ubiquitin protein ligase family member 2	97911	0.08
chr2_33682944_33683139	0.29	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	72	0.98
chr4_55555755_55555906	0.29	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	31745	0.25
chr1_201524755_201524906	0.29	CSRP1	cysteine and glycine-rich protein 1	46246	0.1
chr20_52352229_52352983	0.29	ENSG00000238468	.	67309	0.12
chr22_24906519_24906756	0.29	AP000355.2		5839	0.15
chr1_231242166_231242317	0.28	TRIM67	tripartite motif containing 67	55617	0.1
chr15_25916381_25916532	0.28	ATP10A	ATPase, class V, type 10A	23516	0.19
chr2_178332517_178332770	0.28	AGPS	alkylglycerone phosphate synthase	75147	0.07
chr11_94502979_94503226	0.28	AMOTL1	angiomotin like 1	1565	0.45
chr13_31774982_31775836	0.28	B3GALTL	beta 1,3-galactosyltransferase-like	1336	0.55
chr8_56805555_56805843	0.28	RP11-318K15.2		455	0.77
chr7_75340828_75341228	0.28	HIP1	huntingtin interacting protein 1	27231	0.18
chr11_35936641_35936792	0.28	RP11-698N11.2		3552	0.24
chr8_23830707_23830858	0.27	ENSG00000207201	.	103889	0.07
chr2_149372066_149372403	0.27	EPC2	enhancer of polycomb homolog 2 (Drosophila)	29775	0.24
chr6_108724802_108724953	0.27	ENSG00000200799	.	11600	0.25
chr2_216363831_216363982	0.27	AC012462.1		62930	0.13
chr6_14639404_14639617	0.27	ENSG00000206960	.	7256	0.34
chr17_66576104_66576255	0.27	FAM20A	family with sequence similarity 20, member A	21351	0.19
chr18_2068827_2069125	0.27	METTL4	methyltransferase like 4	485715	0.0
chr11_3951087_3951238	0.27	ENSG00000206976	.	7365	0.17
chr12_66269655_66269806	0.27	RP11-366L20.2	Uncharacterized protein	5628	0.2
chr3_149050046_149050197	0.26	TM4SF18	transmembrane 4 L six family member 18	1148	0.5
chr10_60494716_60495008	0.26	BICC1	bicaudal C homolog 1 (Drosophila)	58433	0.16
chrX_9057871_9058145	0.26	ENSG00000200852	.	43861	0.18
chr5_149424420_149424712	0.26	ENSG00000238369	.	15551	0.14
chr2_178603600_178603751	0.26	AC012499.1		40457	0.17
chr6_73470213_73470364	0.26	KCNQ5-IT1	KCNQ5 intronic transcript 1 (non-protein coding)	130065	0.05
chr7_75341580_75341927	0.26	HIP1	huntingtin interacting protein 1	26506	0.18
chr16_84770743_84770894	0.26	USP10	ubiquitin specific peptidase 10	31053	0.17
chr17_74102777_74103137	0.25	EXOC7	exocyst complex component 7	3089	0.15
chr12_70713258_70713711	0.25	CNOT2	CCR4-NOT transcription complex, subunit 2	12694	0.23
chr4_186842803_186842954	0.25	ENSG00000239034	.	24359	0.19
chr13_78734998_78735287	0.25	RNF219-AS1	RNF219 antisense RNA 1	105852	0.08
chr12_46867069_46867237	0.25	SLC38A2	solute carrier family 38, member 2	100503	0.08
chr6_16903564_16904059	0.25	RP1-151F17.1		141668	0.05
chr2_225812839_225813395	0.24	DOCK10	dedicator of cytokinesis 10	1335	0.59
chr11_94661181_94661856	0.24	RP11-856F16.2		2832	0.29
chr11_43855503_43855654	0.24	RP11-613D13.5		86	0.98
chr7_114659768_114659936	0.24	MDFIC	MyoD family inhibitor domain containing	85928	0.11
chr12_89340554_89340705	0.24	ENSG00000238302	.	335433	0.01
chr3_143676802_143676953	0.24	C3orf58	chromosome 3 open reading frame 58	13763	0.3
chr1_239905020_239905171	0.24	ENSG00000233355	.	11330	0.25
chr21_17584166_17584317	0.24	ENSG00000201025	.	72848	0.13
chr11_129313202_129313353	0.24	BARX2	BARX homeobox 2	1301	0.61
chr3_188139903_188140281	0.24	LPP-AS1	LPP antisense RNA 1	146362	0.04
chr9_124122125_124122321	0.24	STOM	stomatin	10260	0.15
chr22_30586930_30587243	0.23	RP3-438O4.4		16012	0.14
chr8_131307946_131308498	0.23	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	44961	0.19
chr6_140204099_140204250	0.23	ENSG00000252107	.	275657	0.02
chr2_28556445_28556596	0.23	AC093690.1		23194	0.18
chr2_30644578_30644729	0.23	ENSG00000221377	.	10661	0.24
chr8_82265328_82265556	0.23	RP11-363E6.3		71761	0.09
chrX_38468479_38468630	0.23	ENSG00000238606	.	1086	0.63
chr2_169506366_169506517	0.23	ENSG00000199348	.	43435	0.16
chr15_42897406_42897557	0.23	STARD9	StAR-related lipid transfer (START) domain containing 9	29624	0.13
chr1_55828154_55828305	0.23	ENSG00000199831	.	14296	0.23
chr1_161743421_161743663	0.23	ATF6	activating transcription factor 6	7458	0.13
chr7_96467239_96467390	0.23	ENSG00000244318	.	102362	0.07
chr4_86629687_86629838	0.22	ENSG00000266421	.	13859	0.27
chr10_18498286_18498555	0.22	CACNB2	calcium channel, voltage-dependent, beta 2 subunit	51278	0.15
chr6_120007930_120008081	0.22	ENSG00000265725	.	328320	0.01
chr2_158163071_158163471	0.22	ENSG00000222404	.	7601	0.22
chr6_143023055_143023206	0.22	RP1-67K17.3		46450	0.19
chr2_68543161_68543312	0.22	CNRIP1	cannabinoid receptor interacting protein 1	3296	0.21
chr4_41180087_41180238	0.22	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	36313	0.15
chr21_34613920_34614547	0.22	AP000295.9		4846	0.16
chr14_22950410_22950822	0.22	TRAJ55	T cell receptor alpha joining 55 (pseudogene)	70	0.8
chr20_2901732_2901883	0.22	PTPRA	protein tyrosine phosphatase, receptor type, A	2046	0.31
chr4_71503415_71503566	0.22	ENAM	enamelin	9029	0.14
chr10_34490797_34490948	0.22	ENSG00000199200	.	130	0.98
chr5_138542726_138542908	0.22	SIL1	SIL1 nucleotide exchange factor	8730	0.16
chr12_123568411_123568661	0.22	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	2656	0.27
chrX_64748269_64748420	0.22	LAS1L	LAS1-like (S. cerevisiae)	4847	0.28
chr4_48207485_48207636	0.22	ENSG00000202014	.	52109	0.12
chr7_2843960_2844111	0.21	GNA12	guanine nucleotide binding protein (G protein) alpha 12	10857	0.26
chr15_102040487_102040709	0.21	PCSK6	proprotein convertase subtilisin/kexin type 6	10411	0.26
chr17_42247977_42248128	0.21	ASB16	ankyrin repeat and SOCS box containing 16	22	0.94
chr4_9929319_9929470	0.21	RP13-560N11.1		4956	0.26
chr2_217955017_217955405	0.21	ENSG00000251849	.	86010	0.09
chr1_183578719_183579088	0.21	NCF2	neutrophil cytosolic factor 2	18892	0.16
chr2_118861943_118862094	0.21	INSIG2	insulin induced gene 2	15968	0.23
chr22_50330984_50331151	0.21	CRELD2	cysteine-rich with EGF-like domains 2	18686	0.15
chr16_88754480_88754631	0.21	SNAI3	snail family zinc finger 3	1654	0.16
chr8_66507426_66507577	0.21	ENSG00000200714	.	2535	0.33
chr5_90410370_90410521	0.21	ENSG00000199643	.	156099	0.04
chr12_118784249_118784708	0.21	TAOK3	TAO kinase 3	12432	0.24
chr16_88448984_88449499	0.21	ZNF469	zinc finger protein 469	44638	0.14
chr16_69601308_69601964	0.21	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	1382	0.36
chr2_65633649_65633902	0.21	SPRED2	sprouty-related, EVH1 domain containing 2	25536	0.19
chr1_112462912_112463063	0.21	KCND3-AS1	KCND3 antisense RNA 1	10680	0.23
chr16_48478901_48479413	0.21	RP11-44I10.6		3152	0.22
chr10_71239313_71239464	0.20	TSPAN15	tetraspanin 15	4236	0.26
chr16_11195081_11195232	0.20	CLEC16A	C-type lectin domain family 16, member A	22444	0.16
chr6_16824855_16825024	0.20	RP1-151F17.1		62796	0.13
chr22_24186722_24186873	0.20	DERL3	derlin 3	5598	0.1
chr14_103121720_103121871	0.20	ENSG00000202459	.	39930	0.14
chr1_81677570_81677938	0.20	ENSG00000223026	.	39720	0.21
chr6_150131484_150131635	0.20	RP11-350J20.5		12251	0.13
chr6_82970810_82970961	0.20	IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	13414	0.26
chr1_25297951_25298189	0.20	RUNX3	runt-related transcription factor 3	6569	0.21
chr2_65138467_65138618	0.20	ENSG00000238696	.	2722	0.24
chrX_117632578_117633370	0.20	DOCK11	dedicator of cytokinesis 11	3102	0.33
chr14_75665184_75665335	0.20	ENSG00000252013	.	3613	0.19
chr10_98429524_98429700	0.20	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	244	0.94
chr20_52715129_52715347	0.20	BCAS1	breast carcinoma amplified sequence 1	27934	0.18
chr14_70921495_70921646	0.20	ADAM21	ADAM metallopeptidase domain 21	2647	0.27
chr4_79578557_79578708	0.19	ENSG00000238816	.	17378	0.2
chr13_31381021_31381172	0.19	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	71451	0.11
chr5_74465276_74465427	0.19	ANKRD31	ankyrin repeat domain 31	67352	0.12
chr2_171921049_171921298	0.19	TLK1	tousled-like kinase 1	2273	0.4
chr5_160121300_160121451	0.19	CTC-529G1.1		9017	0.21
chr3_143085241_143085392	0.19	SLC9A9-AS2	SLC9A9 antisense RNA 2	14864	0.21
chr21_19260646_19260797	0.19	ENSG00000221335	.	3307	0.27
chr13_45553454_45553605	0.19	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	10089	0.18
chr4_71814858_71815009	0.19	DCK	deoxycytidine kinase	43322	0.14
chr12_9268627_9268778	0.19	A2M	alpha-2-macroglobulin	51	0.97
chr22_51016890_51017529	0.19	CPT1B	carnitine palmitoyltransferase 1B (muscle)	113	0.91
chr2_238570999_238571408	0.19	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	29585	0.17
chr7_121012833_121012984	0.19	FAM3C	family with sequence similarity 3, member C	23454	0.22
chr2_204553524_204553955	0.19	CD28	CD28 molecule	17459	0.24
chr12_105013205_105013356	0.19	ENSG00000264295	.	27869	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.5	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.2	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0048179	activin receptor complex(GO:0048179)
0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.2	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.2	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle