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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MEF2B

Z-value: 1.10

Motif logo

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
MEF2B
ENSG00000213999.11 myocyte enhancer factor 2B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_19271531_19271682MEF2B94480.1062360.791.2e-02Click!
chr19_19266537_19266688MEF2B144420.1021330.742.4e-02Click!
chr19_19270273_19270424MEF2B107060.1050190.521.5e-01Click!
chr19_19282891_19283042MEF2B18680.1984390.511.6e-01Click!
chr19_19271102_19271312MEF2B98470.1058210.462.1e-01Click!

Activity of the MEF2B motif across conditions

Conditions sorted by the z-value of the MEF2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_83043773_83044235 0.62 LPHN2
 latrophilin 2
 598431
 0.0
chr10_114786502_114786745 0.57 RP11-57H14.2
74989
 0.11
chr6_85293592_85293821 0.57 RP11-132M7.3
105437
 0.08
chr3_177053679_177054041 0.55 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 138599
 0.05
chr13_101149154_101149445 0.53 PCCA-AS1
 PCCA antisense RNA 1
 15888
 0.18
chr20_23132592_23133523 0.51 ENSG00000201527
 .
 8551
 0.22
chr13_30627332_30627483 0.50 LINC00572
 long intergenic non-protein coding RNA 572
 126619
 0.06
chr6_114130369_114130564 0.50 ENSG00000253091
 .
 27799
 0.16
chr6_25179466_25179765 0.48 ENSG00000222373
 .
 13026
 0.19
chr1_168467710_168467921 0.48 XCL2
 chemokine (C motif) ligand 2
 45420
 0.16
chr3_63908528_63908748 0.48 ATXN7
 ataxin 7
 10363
 0.18
chr4_86747445_86747851 0.47 ARHGAP24
 Rho GTPase activating protein 24
 1250
 0.59
chr1_184476924_184477075 0.46 GS1-115G20.1
99528
 0.07
chr5_148796784_148796935 0.46 ENSG00000208035
 .
 11622
 0.13
chr1_50575855_50576371 0.45 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
 735
 0.74
chr14_56777353_56777504 0.43 TMEM260
 transmembrane protein 260
 177644
 0.03
chr1_61299199_61299350 0.41 NFIA
 nuclear factor I/A
 31657
 0.24
chr5_124237918_124238155 0.41 ZNF608
 zinc finger protein 608
 153536
 0.04
chr1_234656705_234656856 0.41 TARBP1
 TAR (HIV-1) RNA binding protein 1
 41931
 0.14
chr3_48597793_48598316 0.40 PFKFB4
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
 508
 0.63
chr2_173258743_173259031 0.40 ITGA6
 integrin, alpha 6
 33195
 0.16
chr16_73200279_73201088 0.40 C16orf47
 chromosome 16 open reading frame 47
 22337
 0.26
chr11_69264083_69264234 0.40 CCND1
 cyclin D1
 191697
 0.03
chr15_42651493_42651677 0.40 CAPN3
 calpain 3, (p94)
 198
 0.94
chr6_37519897_37520048 0.40 ENSG00000263926
 .
 3226
 0.29
chr16_75086975_75087126 0.39 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 50855
 0.11
chr20_3358805_3359063 0.38 ENSG00000201346
 .
 5942
 0.16
chr8_17547050_17547201 0.37 ENSG00000265520
 .
 7959
 0.17
chr2_208896310_208896486 0.37 PLEKHM3
 pleckstrin homology domain containing, family M, member 3
 6114
 0.15
chr21_39193991_39194257 0.37 KCNJ6
 potassium inwardly-rectifying channel, subfamily J, member 6
 91433
 0.08
chr8_120627310_120627516 0.36 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 22165
 0.24
chr8_108316239_108316473 0.36 ANGPT1
 angiopoietin 1
 32394
 0.22
chr2_158697443_158697594 0.35 ACVR1
 activin A receptor, type I
 2679
 0.28
chr12_3764521_3764672 0.35 EFCAB4B
 EF-hand calcium binding domain 4B
 1207
 0.6
chr5_75367452_75367603 0.35 SV2C
 synaptic vesicle glycoprotein 2C
 11470
 0.24
chr14_105721504_105721672 0.35 BRF1
 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
 5847
 0.17
chr17_6503024_6503317 0.35 ENSG00000200914
 .
 1201
 0.36
chr11_124595331_124595482 0.35 NRGN
 neurogranin (protein kinase C substrate, RC3)
 14336
 0.1
chr14_39317605_39317829 0.34 ENSG00000199285
 .
 138768
 0.05
chr8_97803430_97803993 0.34 CPQ
 carboxypeptidase Q
 30243
 0.25
chr17_66315705_66315870 0.34 ARSG
 arylsulfatase G
 28128
 0.15
chr1_157745151_157745302 0.34 FCRL2
 Fc receptor-like 2
 1683
 0.39
chr15_39850731_39850882 0.33 THBS1
 thrombospondin 1
 22474
 0.19
chr12_12032698_12032849 0.33 ETV6
 ets variant 6
 6098
 0.32
chr1_68056079_68056230 0.33 ENSG00000207504
 .
 49344
 0.14
chr9_101803098_101803249 0.33 TGFBR1
 transforming growth factor, beta receptor 1
 63147
 0.11
chr2_113429205_113429356 0.33 SLC20A1
 solute carrier family 20 (phosphate transporter), member 1
 24001
 0.17
chr12_15842783_15842934 0.32 ENSG00000200105
 .
 18114
 0.22
chr7_29283267_29283581 0.32 AC004593.3
34838
 0.16
chr2_202819063_202819214 0.32 ENSG00000221489
 .
 1079
 0.52
chr2_43443107_43443258 0.32 ZFP36L2
 ZFP36 ring finger protein-like 2
 10566
 0.23
chr22_27714638_27714789 0.32 ENSG00000200443
 .
 282863
 0.01
chr16_84413717_84413987 0.31 ATP2C2
 ATPase, Ca++ transporting, type 2C, member 2
 11719
 0.19
chr5_75722311_75722532 0.31 IQGAP2
 IQ motif containing GTPase activating protein 2
 22172
 0.25
chr3_171038529_171038680 0.31 TNIK
 TRAF2 and NCK interacting kinase
 95104
 0.08
chr5_74615457_74615613 0.31 HMGCR
 3-hydroxy-3-methylglutaryl-CoA reductase
 16619
 0.19
chr2_155312519_155312670 0.31 AC009227.2
1356
 0.52
chr4_88832400_88832551 0.31 SPP1
 secreted phosphoprotein 1
 64344
 0.1
chr7_129630529_129630680 0.31 ENSG00000263557
 .
 5017
 0.14
chr11_34469686_34469883 0.31 CAT
 catalase
 9312
 0.22
chr16_46689835_46690025 0.30 RP11-93O14.2
5573
 0.18
chr1_235051769_235052023 0.30 ENSG00000239690
 .
 11963
 0.27
chr12_11932326_11932519 0.30 ETV6
 ets variant 6
 26987
 0.25
chr14_85775279_85775646 0.30 ENSG00000252529
 .
 37186
 0.24
chr3_149160811_149161262 0.30 TM4SF4
 transmembrane 4 L six family member 4
 30725
 0.16
chr20_17649733_17649884 0.30 RRBP1
 ribosome binding protein 1
 8656
 0.21
chr19_19245450_19245992 0.30 TMEM161A
 transmembrane protein 161A
 2511
 0.19
chr3_148477195_148477534 0.30 AGTR1
 angiotensin II receptor, type 1
 19779
 0.22
chr9_124123057_124123675 0.30 STOM
 stomatin
 9117
 0.15
chr12_49626641_49626792 0.30 TUBA1C
 tubulin, alpha 1c
 5007
 0.14
chr2_55345739_55346346 0.29 RTN4
 reticulon 4
 6285
 0.2
chr13_91415783_91415934 0.29 ENSG00000251753
 .
 18265
 0.31
chr14_73881705_73881856 0.29 NUMB
 numb homolog (Drosophila)
 5001
 0.21
chr2_218766852_218767096 0.29 TNS1
 tensin 1
 242
 0.95
chr3_140795767_140796225 0.29 SPSB4
 splA/ryanodine receptor domain and SOCS box containing 4
 25752
 0.2
chr12_392843_392994 0.29 RP11-283I3.6
6629
 0.16
chr7_70907526_70907677 0.29 ENSG00000266688
 .
 132064
 0.05
chr14_56683663_56683814 0.29 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 97911
 0.08
chr2_33682944_33683139 0.29 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
 72
 0.98
chr4_55555755_55555906 0.29 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 31745
 0.25
chr1_201524755_201524906 0.29 CSRP1
 cysteine and glycine-rich protein 1
 46246
 0.1
chr20_52352229_52352983 0.29 ENSG00000238468
 .
 67309
 0.12
chr22_24906519_24906756 0.29 AP000355.2
5839
 0.15
chr1_231242166_231242317 0.28 TRIM67
 tripartite motif containing 67
 55617
 0.1
chr15_25916381_25916532 0.28 ATP10A
 ATPase, class V, type 10A
 23516
 0.19
chr2_178332517_178332770 0.28 AGPS
 alkylglycerone phosphate synthase
 75147
 0.07
chr11_94502979_94503226 0.28 AMOTL1
 angiomotin like 1
 1565
 0.45
chr13_31774982_31775836 0.28 B3GALTL
 beta 1,3-galactosyltransferase-like
 1336
 0.55
chr8_56805555_56805843 0.28 RP11-318K15.2
455
 0.77
chr7_75340828_75341228 0.28 HIP1
 huntingtin interacting protein 1
 27231
 0.18
chr11_35936641_35936792 0.28 RP11-698N11.2
3552
 0.24
chr8_23830707_23830858 0.27 ENSG00000207201
 .
 103889
 0.07
chr2_149372066_149372403 0.27 EPC2
 enhancer of polycomb homolog 2 (Drosophila)
 29775
 0.24
chr6_108724802_108724953 0.27 ENSG00000200799
 .
 11600
 0.25
chr2_216363831_216363982 0.27 AC012462.1
62930
 0.13
chr6_14639404_14639617 0.27 ENSG00000206960
 .
 7256
 0.34
chr17_66576104_66576255 0.27 FAM20A
 family with sequence similarity 20, member A
 21351
 0.19
chr18_2068827_2069125 0.27 METTL4
 methyltransferase like 4
 485715
 0.0
chr11_3951087_3951238 0.27 ENSG00000206976
 .
 7365
 0.17
chr12_66269655_66269806 0.27 RP11-366L20.2
 Uncharacterized protein
 5628
 0.2
chr3_149050046_149050197 0.26 TM4SF18
 transmembrane 4 L six family member 18
 1148
 0.5
chr10_60494716_60495008 0.26 BICC1
 bicaudal C homolog 1 (Drosophila)
 58433
 0.16
chrX_9057871_9058145 0.26 ENSG00000200852
 .
 43861
 0.18
chr5_149424420_149424712 0.26 ENSG00000238369
 .
 15551
 0.14
chr2_178603600_178603751 0.26 AC012499.1
40457
 0.17
chr6_73470213_73470364 0.26 KCNQ5-IT1
 KCNQ5 intronic transcript 1 (non-protein coding)
 130065
 0.05
chr7_75341580_75341927 0.26 HIP1
 huntingtin interacting protein 1
 26506
 0.18
chr16_84770743_84770894 0.26 USP10
 ubiquitin specific peptidase 10
 31053
 0.17
chr17_74102777_74103137 0.25 EXOC7
 exocyst complex component 7
 3089
 0.15
chr12_70713258_70713711 0.25 CNOT2
 CCR4-NOT transcription complex, subunit 2
 12694
 0.23
chr4_186842803_186842954 0.25 ENSG00000239034
 .
 24359
 0.19
chr13_78734998_78735287 0.25 RNF219-AS1
 RNF219 antisense RNA 1
 105852
 0.08
chr12_46867069_46867237 0.25 SLC38A2
 solute carrier family 38, member 2
 100503
 0.08
chr6_16903564_16904059 0.25 RP1-151F17.1
141668
 0.05
chr2_225812839_225813395 0.24 DOCK10
 dedicator of cytokinesis 10
 1335
 0.59
chr11_94661181_94661856 0.24 RP11-856F16.2
2832
 0.29
chr11_43855503_43855654 0.24 RP11-613D13.5
86
 0.98
chr7_114659768_114659936 0.24 MDFIC
 MyoD family inhibitor domain containing
 85928
 0.11
chr12_89340554_89340705 0.24 ENSG00000238302
 .
 335433
 0.01
chr3_143676802_143676953 0.24 C3orf58
 chromosome 3 open reading frame 58
 13763
 0.3
chr1_239905020_239905171 0.24 ENSG00000233355
 .
 11330
 0.25
chr21_17584166_17584317 0.24 ENSG00000201025
 .
 72848
 0.13
chr11_129313202_129313353 0.24 BARX2
 BARX homeobox 2
 1301
 0.61
chr3_188139903_188140281 0.24 LPP-AS1
 LPP antisense RNA 1
 146362
 0.04
chr9_124122125_124122321 0.24 STOM
 stomatin
 10260
 0.15
chr22_30586930_30587243 0.23 RP3-438O4.4
16012
 0.14
chr8_131307946_131308498 0.23 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 44961
 0.19
chr6_140204099_140204250 0.23 ENSG00000252107
 .
 275657
 0.02
chr2_28556445_28556596 0.23 AC093690.1
23194
 0.18
chr2_30644578_30644729 0.23 ENSG00000221377
 .
 10661
 0.24
chr8_82265328_82265556 0.23 RP11-363E6.3
71761
 0.09
chrX_38468479_38468630 0.23 ENSG00000238606
 .
 1086
 0.63
chr2_169506366_169506517 0.23 ENSG00000199348
 .
 43435
 0.16
chr15_42897406_42897557 0.23 STARD9
 StAR-related lipid transfer (START) domain containing 9
 29624
 0.13
chr1_55828154_55828305 0.23 ENSG00000199831
 .
 14296
 0.23
chr1_161743421_161743663 0.23 ATF6
 activating transcription factor 6
 7458
 0.13
chr7_96467239_96467390 0.23 ENSG00000244318
 .
 102362
 0.07
chr4_86629687_86629838 0.22 ENSG00000266421
 .
 13859
 0.27
chr10_18498286_18498555 0.22 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
 51278
 0.15
chr6_120007930_120008081 0.22 ENSG00000265725
 .
 328320
 0.01
chr2_158163071_158163471 0.22 ENSG00000222404
 .
 7601
 0.22
chr6_143023055_143023206 0.22 RP1-67K17.3
46450
 0.19
chr2_68543161_68543312 0.22 CNRIP1
 cannabinoid receptor interacting protein 1
 3296
 0.21
chr4_41180087_41180238 0.22 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 36313
 0.15
chr21_34613920_34614547 0.22 AP000295.9
4846
 0.16
chr14_22950410_22950822 0.22 TRAJ55
 T cell receptor alpha joining 55 (pseudogene)
 70
 0.8
chr20_2901732_2901883 0.22 PTPRA
 protein tyrosine phosphatase, receptor type, A
 2046
 0.31
chr4_71503415_71503566 0.22 ENAM
 enamelin
 9029
 0.14
chr10_34490797_34490948 0.22 ENSG00000199200
 .
 130
 0.98
chr5_138542726_138542908 0.22 SIL1
 SIL1 nucleotide exchange factor
 8730
 0.16
chr12_123568411_123568661 0.22 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 2656
 0.27
chrX_64748269_64748420 0.22 LAS1L
 LAS1-like (S. cerevisiae)
 4847
 0.28
chr4_48207485_48207636 0.22 ENSG00000202014
 .
 52109
 0.12
chr7_2843960_2844111 0.21 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 10857
 0.26
chr15_102040487_102040709 0.21 PCSK6
 proprotein convertase subtilisin/kexin type 6
 10411
 0.26
chr17_42247977_42248128 0.21 ASB16
 ankyrin repeat and SOCS box containing 16
 22
 0.94
chr4_9929319_9929470 0.21 RP13-560N11.1
4956
 0.26
chr2_217955017_217955405 0.21 ENSG00000251849
 .
 86010
 0.09
chr1_183578719_183579088 0.21 NCF2
 neutrophil cytosolic factor 2
 18892
 0.16
chr2_118861943_118862094 0.21 INSIG2
 insulin induced gene 2
 15968
 0.23
chr22_50330984_50331151 0.21 CRELD2
 cysteine-rich with EGF-like domains 2
 18686
 0.15
chr16_88754480_88754631 0.21 SNAI3
 snail family zinc finger 3
 1654
 0.16
chr8_66507426_66507577 0.21 ENSG00000200714
 .
 2535
 0.33
chr5_90410370_90410521 0.21 ENSG00000199643
 .
 156099
 0.04
chr12_118784249_118784708 0.21 TAOK3
 TAO kinase 3
 12432
 0.24
chr16_88448984_88449499 0.21 ZNF469
 zinc finger protein 469
 44638
 0.14
chr16_69601308_69601964 0.21 NFAT5
 nuclear factor of activated T-cells 5, tonicity-responsive
 1382
 0.36
chr2_65633649_65633902 0.21 SPRED2
 sprouty-related, EVH1 domain containing 2
 25536
 0.19
chr1_112462912_112463063 0.21 KCND3-AS1
 KCND3 antisense RNA 1
 10680
 0.23
chr16_48478901_48479413 0.21 RP11-44I10.6
3152
 0.22
chr10_71239313_71239464 0.20 TSPAN15
 tetraspanin 15
 4236
 0.26
chr16_11195081_11195232 0.20 CLEC16A
 C-type lectin domain family 16, member A
 22444
 0.16
chr6_16824855_16825024 0.20 RP1-151F17.1
62796
 0.13
chr22_24186722_24186873 0.20 DERL3
 derlin 3
 5598
 0.1
chr14_103121720_103121871 0.20 ENSG00000202459
 .
 39930
 0.14
chr1_81677570_81677938 0.20 ENSG00000223026
 .
 39720
 0.21
chr6_150131484_150131635 0.20 RP11-350J20.5
12251
 0.13
chr6_82970810_82970961 0.20 IBTK
 inhibitor of Bruton agammaglobulinemia tyrosine kinase
 13414
 0.26
chr1_25297951_25298189 0.20 RUNX3
 runt-related transcription factor 3
 6569
 0.21
chr2_65138467_65138618 0.20 ENSG00000238696
 .
 2722
 0.24
chrX_117632578_117633370 0.20 DOCK11
 dedicator of cytokinesis 11
 3102
 0.33
chr14_75665184_75665335 0.20 ENSG00000252013
 .
 3613
 0.19
chr10_98429524_98429700 0.20 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 244
 0.94
chr20_52715129_52715347 0.20 BCAS1
 breast carcinoma amplified sequence 1
 27934
 0.18
chr14_70921495_70921646 0.20 ADAM21
 ADAM metallopeptidase domain 21
 2647
 0.27
chr4_79578557_79578708 0.19 ENSG00000238816
 .
 17378
 0.2
chr13_31381021_31381172 0.19 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 71451
 0.11
chr5_74465276_74465427 0.19 ANKRD31
 ankyrin repeat domain 31
 67352
 0.12
chr2_171921049_171921298 0.19 TLK1
 tousled-like kinase 1
 2273
 0.4
chr5_160121300_160121451 0.19 CTC-529G1.1
9017
 0.21
chr3_143085241_143085392 0.19 SLC9A9-AS2
 SLC9A9 antisense RNA 2
 14864
 0.21
chr21_19260646_19260797 0.19 ENSG00000221335
 .
 3307
 0.27
chr13_45553454_45553605 0.19 NUFIP1
 nuclear fragile X mental retardation protein interacting protein 1
 10089
 0.18
chr4_71814858_71815009 0.19 DCK
 deoxycytidine kinase
 43322
 0.14
chr12_9268627_9268778 0.19 A2M
 alpha-2-macroglobulin
 51
 0.97
chr22_51016890_51017529 0.19 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
 113
 0.91
chr2_238570999_238571408 0.19 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 29585
 0.17
chr7_121012833_121012984 0.19 FAM3C
 family with sequence similarity 3, member C
 23454
 0.22
chr2_204553524_204553955 0.19 CD28
 CD28 molecule
 17459
 0.24
chr12_105013205_105013356 0.19 ENSG00000264295
 .
 27869
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.2 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle