Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for MEF2C

Z-value: 3.34

Motif logo

Transcription factors associated with MEF2C

Gene Symbol	Gene ID	Gene Info
MEF2C Ensembl NCBI GeneCards UniProt	ENSG00000081189.9	myocyte enhancer factor 2C

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_88078807_88078958	MEF2C	40723	0.176129	0.87	2.0e-03	Click!
chr5_88082371_88082821	MEF2C	37009	0.188026	0.80	9.1e-03	Click!
chr5_88173800_88173951	MEF2C	81	0.978762	0.80	9.7e-03	Click!
chr5_88110141_88110292	MEF2C	9389	0.269479	0.78	1.2e-02	Click!
chr5_88174505_88174656	MEF2C	786	0.700337	0.78	1.3e-02	Click!

Activity of the MEF2C motif across conditions

Conditions sorted by the z-value of the MEF2C motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_81460698_81461288	1.75	ENSG00000265684	.	86747	0.08
chr4_186629734_186630027	1.72	ENSG00000207497	.	1241	0.48
chr7_129665295_129665446	1.56	ENSG00000201109	.	1747	0.26
chr3_149160811_149161262	1.52	TM4SF4	transmembrane 4 L six family member 4	30725	0.16
chr17_73440413_73440657	1.44	KIAA0195	KIAA0195	3295	0.13
chr6_85293592_85293821	1.40	RP11-132M7.3		105437	0.08
chr5_115789878_115790274	1.39	CTB-118N6.3		4650	0.26
chr1_83043773_83044235	1.39	LPHN2	latrophilin 2	598431	0.0
chr1_68638974_68639247	1.38	ENSG00000221203	.	10183	0.22
chr9_110037719_110038006	1.36	RAD23B	RAD23 homolog B (S. cerevisiae)	7556	0.31
chr5_95482244_95482395	1.32	ENSG00000206997	.	63612	0.12
chr5_52105602_52106304	1.27	CTD-2288O8.1		22093	0.18
chr1_64472340_64472533	1.25	ENSG00000207190	.	22236	0.22
chr4_41180087_41180238	1.24	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	36313	0.15
chr3_177053679_177054041	1.24	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	138599	0.05
chr11_119232707_119232858	1.23	USP2	ubiquitin specific peptidase 2	2135	0.15
chr12_66050940_66051359	1.22	HMGA2	high mobility group AT-hook 2	166762	0.03
chr5_123121246_123121397	1.20	CSNK1G3	casein kinase 1, gamma 3	197202	0.03
chr20_23132592_23133523	1.19	ENSG00000201527	.	8551	0.22
chr11_27487003_27487154	1.17	RP11-159H22.2		6198	0.18
chr21_43377285_43377631	1.16	C2CD2	C2 calcium-dependent domain containing 2	3459	0.24
chr16_30319410_30320623	1.15	RP11-347C12.2		26359	0.08
chr11_94661181_94661856	1.14	RP11-856F16.2		2832	0.29
chr6_45486037_45486188	1.14	RUNX2	runt-related transcription factor 2	95890	0.08
chr2_173258743_173259031	1.14	ITGA6	integrin, alpha 6	33195	0.16
chr14_61568522_61568874	1.13	SLC38A6	solute carrier family 38, member 6	58830	0.13
chr10_105405543_105405694	1.13	SH3PXD2A	SH3 and PX domains 2A	15844	0.16
chr10_14778717_14778868	1.12	FAM107B	family with sequence similarity 107, member B	38104	0.16
chr2_38324502_38325000	1.12	CYP1B1-AS1	CYP1B1 antisense RNA 1	971	0.56
chr2_218766852_218767096	1.12	TNS1	tensin 1	242	0.95
chr2_9467301_9467669	1.11	ITGB1BP1	integrin beta 1 binding protein 1	92938	0.07
chr5_167831336_167831487	1.10	WWC1	WW and C2 domain containing 1	1873	0.44
chr9_108062111_108062384	1.10	SLC44A1	solute carrier family 44 (choline transporter), member 1	55344	0.16
chr12_31738710_31738861	1.10	DENND5B-AS1	DENND5B antisense RNA 1	4072	0.18
chr10_74498015_74498488	1.10	ENSG00000266719	.	17464	0.16
chr12_66269655_66269806	1.09	RP11-366L20.2	Uncharacterized protein	5628	0.2
chr1_207199417_207199625	1.08	C1orf116	chromosome 1 open reading frame 116	6571	0.14
chr5_148796784_148796935	1.08	ENSG00000208035	.	11622	0.13
chr20_47299343_47299823	1.08	ENSG00000251876	.	56402	0.16
chr3_188296487_188296899	1.07	LPP-AS1	LPP antisense RNA 1	10239	0.22
chr22_36181419_36181847	1.06	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	7554	0.27
chr8_108311245_108311481	1.05	ANGPT1	angiopoietin 1	37387	0.2
chr7_112124918_112125112	1.05	LSMEM1	leucine-rich single-pass membrane protein 1	3969	0.27
chr2_218715975_218716307	1.04	TNS1	tensin 1	9258	0.27
chr11_10609186_10609457	1.02	MRVI1-AS1	MRVI1 antisense RNA 1	5423	0.19
chr1_68056079_68056230	1.02	ENSG00000207504	.	49344	0.14
chr2_43135820_43135971	1.01	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	116163	0.06
chr1_118679034_118679185	1.00	SPAG17	sperm associated antigen 17	48737	0.18
chr5_173382092_173382267	1.00	C5orf47	chromosome 5 open reading frame 47	33983	0.18
chr16_46782782_46782933	0.98	MYLK3	myosin light chain kinase 3	636	0.74
chr5_172879337_172879488	0.98	ENSG00000199219	.	90169	0.08
chr5_134769606_134770119	0.96	C5orf20	chromosome 5 open reading frame 20	13176	0.14
chr6_106511937_106512088	0.96	PRDM1	PR domain containing 1, with ZNF domain	22183	0.22
chr1_202545648_202545889	0.95	RP11-569A11.1		27628	0.17
chr19_11314159_11314310	0.95	CTC-510F12.2		70	0.94
chr3_159571661_159571972	0.95	SCHIP1	schwannomin interacting protein 1	1088	0.53
chr11_12715053_12715211	0.95	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	18082	0.26
chr11_65261959_65262206	0.94	SCYL1	SCY1-like 1 (S. cerevisiae)	30466	0.09
chr5_124237918_124238155	0.94	ZNF608	zinc finger protein 608	153536	0.04
chr8_125827870_125828161	0.93	ENSG00000263735	.	6285	0.28
chr16_48478901_48479413	0.93	RP11-44I10.6		3152	0.22
chr3_189766577_189766728	0.93	ENSG00000265045	.	65071	0.1
chr3_159570434_159570853	0.93	SCHIP1	schwannomin interacting protein 1	85	0.97
chr9_20980662_20980813	0.92	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	50871	0.12
chr12_2368088_2368351	0.92	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	10723	0.24
chr19_11305700_11305968	0.92	KANK2	KN motif and ankyrin repeat domains 2	34	0.96
chr12_45626252_45626403	0.91	ANO6	anoctamin 6	16424	0.28
chr1_67601319_67601470	0.91	C1orf141	chromosome 1 open reading frame 141	734	0.65
chr3_143245082_143245283	0.91	SLC9A9-AS2	SLC9A9 antisense RNA 2	145002	0.04
chrX_134122511_134122662	0.91	SMIM10	small integral membrane protein 10	2382	0.26
chr21_46550357_46550680	0.90	ADARB1	adenosine deaminase, RNA-specific, B1	9703	0.16
chr1_112462912_112463063	0.90	KCND3-AS1	KCND3 antisense RNA 1	10680	0.23
chr1_54201050_54201201	0.89	GLIS1	GLIS family zinc finger 1	1248	0.47
chr1_184476924_184477075	0.89	GS1-115G20.1		99528	0.07
chr9_38020050_38020293	0.89	SHB	Src homology 2 domain containing adaptor protein B	49037	0.15
chr1_163201216_163201367	0.87	RGS5	regulator of G-protein signaling 5	13865	0.21
chr3_81789805_81790284	0.86	GBE1	glucan (1,4-alpha-), branching enzyme 1	2736	0.44
chr13_101149154_101149445	0.86	PCCA-AS1	PCCA antisense RNA 1	15888	0.18
chr11_12182764_12182915	0.86	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	151	0.97
chr10_45471797_45471948	0.86	C10orf10	chromosome 10 open reading frame 10	2365	0.19
chr11_92436620_92436809	0.85	ENSG00000239086	.	25867	0.23
chr13_47159934_47160146	0.85	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	32645	0.22
chr10_36924110_36924390	0.85	ENSG00000207271	.	9184	0.31
chr4_86853679_86853882	0.84	ARHGAP24	Rho GTPase activating protein 24	2354	0.33
chr7_14875158_14875309	0.84	DGKB	diacylglycerol kinase, beta 90kDa	5739	0.25
chr9_116355859_116356115	0.84	RGS3	regulator of G-protein signaling 3	221	0.94
chr18_67996235_67996386	0.84	RP11-41O4.1	Uncharacterized protein	6365	0.22
chr2_193011657_193011808	0.84	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2	47518	0.19
chr4_122712025_122712176	0.84	EXOSC9	exosome component 9	10372	0.16
chr1_33887997_33888148	0.84	PHC2	polyhomeotic homolog 2 (Drosophila)	8144	0.17
chr6_147212923_147213074	0.84	STXBP5-AS1	STXBP5 antisense RNA 1	19744	0.27
chr20_4032466_4032832	0.84	RP11-352D3.2	Uncharacterized protein	23163	0.18
chr1_208393112_208393658	0.83	PLXNA2	plexin A2	24280	0.28
chr20_17631217_17631686	0.83	RRBP1	ribosome binding protein 1	9701	0.21
chr22_31451478_31451629	0.83	ENSG00000240186	.	4422	0.15
chr14_78029431_78029620	0.82	ENSG00000240233	.	15313	0.16
chr22_24186722_24186873	0.82	DERL3	derlin 3	5598	0.1
chr8_120566171_120566430	0.82	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	38948	0.19
chr15_98509107_98509579	0.82	ARRDC4	arrestin domain containing 4	5415	0.27
chr13_111050298_111050449	0.82	ENSG00000238629	.	16179	0.22
chr1_168467710_168467921	0.81	XCL2	chemokine (C motif) ligand 2	45420	0.16
chr1_21348298_21348860	0.81	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	28816	0.19
chr4_77646086_77646237	0.81	RP11-359D14.2		33466	0.17
chr2_178284315_178284466	0.80	AGPS	alkylglycerone phosphate synthase	26894	0.14
chr1_238643316_238643467	0.80	ENSG00000252371	.	154303	0.04
chr11_69264083_69264234	0.80	CCND1	cyclin D1	191697	0.03
chr16_73200279_73201088	0.79	C16orf47	chromosome 16 open reading frame 47	22337	0.26
chr5_10366297_10366564	0.79	MARCH6	membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase	12551	0.14
chr5_173350639_173351153	0.79	CPEB4	cytoplasmic polyadenylation element binding protein 4	30815	0.2
chr9_76484645_76484796	0.79	ENSG00000212454	.	118727	0.07
chr9_130563551_130563710	0.78	FPGS	folylpolyglutamate synthase	1524	0.2
chr8_17547050_17547201	0.78	ENSG00000265520	.	7959	0.17
chr11_115488521_115488672	0.78	ENSG00000239153	.	9307	0.31
chr2_173686091_173686430	0.78	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4	43	0.99
chr5_39447733_39447884	0.78	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	14594	0.28
chr17_30234922_30235073	0.78	UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)	6213	0.19
chr4_22515546_22516022	0.78	GPR125	G protein-coupled receptor 125	1836	0.52
chr6_13474687_13475178	0.77	AL583828.1		11483	0.16
chr11_7913448_7913599	0.77	ENSG00000252769	.	2697	0.2
chr4_47864972_47865123	0.77	CORIN	corin, serine peptidase	24924	0.18
chr8_68175272_68175423	0.77	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)	4332	0.33
chr1_39608036_39608283	0.77	ENSG00000222378	.	11809	0.17
chr7_134303351_134303502	0.77	BPGM	2,3-bisphosphoglycerate mutase	28134	0.2
chr7_75472006_75472177	0.76	CCL24	chemokine (C-C motif) ligand 24	19417	0.15
chr1_110121167_110121450	0.76	ENSG00000206832	.	12954	0.08
chr15_68645332_68645486	0.76	FEM1B	fem-1 homolog b (C. elegans)	62859	0.11
chr8_8458649_8458942	0.76	ENSG00000263616	.	18630	0.21
chr1_231037337_231037488	0.76	ENSG00000238985	.	6162	0.13
chr11_47209148_47209441	0.76	PACSIN3	protein kinase C and casein kinase substrate in neurons 3	1300	0.28
chr10_18468863_18469014	0.76	CACNB2	calcium channel, voltage-dependent, beta 2 subunit	38829	0.19
chr7_102451596_102451747	0.76	ENSG00000252643	.	23381	0.16
chr11_33734765_33735110	0.75	CD59	CD59 molecule, complement regulatory protein	9065	0.15
chr22_27714638_27714789	0.75	ENSG00000200443	.	282863	0.01
chr3_148477195_148477534	0.75	AGTR1	angiotensin II receptor, type 1	19779	0.22
chr9_92692520_92692671	0.75	ENSG00000263967	.	93222	0.1
chr4_720033_720656	0.75	PCGF3	polycomb group ring finger 3	1448	0.25
chr3_185860146_185860297	0.75	ETV5	ets variant 5	32114	0.19
chr6_7697864_7698510	0.75	BMP6	bone morphogenetic protein 6	28843	0.23
chr3_16506515_16506666	0.74	RFTN1	raftlin, lipid raft linker 1	17782	0.24
chr21_40128002_40128182	0.74	ETS2	v-ets avian erythroblastosis virus E26 oncogene homolog 2	49139	0.17
chr3_186145603_186145754	0.74	DGKG	diacylglycerol kinase, gamma 90kDa	65652	0.11
chr6_139690937_139691976	0.74	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	3894	0.32
chr7_24868611_24868798	0.74	DFNA5	deafness, autosomal dominant 5	59460	0.13
chr2_55345739_55346346	0.74	RTN4	reticulon 4	6285	0.2
chr10_88891932_88892287	0.74	RP11-96C23.9		18398	0.13
chr20_33722296_33722447	0.74	EDEM2	ER degradation enhancer, mannosidase alpha-like 2	10588	0.13
chr7_152010807_152011572	0.74	KMT2C	lysine (K)-specific methyltransferase 2C	66085	0.11
chr2_206634595_206634939	0.73	AC007362.3		6037	0.29
chr14_75754368_75754722	0.73	FOS	FBJ murine osteosarcoma viral oncogene homolog	7649	0.17
chr21_27089790_27089941	0.73	GABPA	GA binding protein transcription factor, alpha subunit 60kDa	17016	0.19
chr12_89763940_89764091	0.73	DUSP6	dual specificity phosphatase 6	16967	0.24
chr18_9850059_9850316	0.73	ENSG00000252680	.	5344	0.19
chr6_16903564_16904059	0.73	RP1-151F17.1		141668	0.05
chr3_170893358_170893509	0.73	TNIK	TRAF2 and NCK interacting kinase	50067	0.16
chr13_91796537_91796800	0.73	ENSG00000215417	.	206191	0.03
chr9_738221_738372	0.72	KANK1	KN motif and ankyrin repeat domains 1	5680	0.27
chr4_186842803_186842954	0.72	ENSG00000239034	.	24359	0.19
chr2_28556445_28556596	0.72	AC093690.1		23194	0.18
chr6_125524204_125524355	0.72	TPD52L1	tumor protein D52-like 1	506	0.87
chr8_131307946_131308498	0.72	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	44961	0.19
chr18_43806284_43806570	0.72	C18orf25	chromosome 18 open reading frame 25	52427	0.13
chr11_75785896_75786202	0.71	UVRAG	UV radiation resistance associated	40908	0.15
chr6_106251962_106252192	0.71	ENSG00000200198	.	100171	0.08
chr13_28146911_28147062	0.71	LNX2	ligand of numb-protein X 2	47555	0.13
chr2_47194923_47195136	0.71	RP11-15I20.1		11002	0.16
chr11_86350068_86350219	0.71	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	33097	0.23
chr5_172305896_172306047	0.71	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	26249	0.16
chr16_46689835_46690025	0.71	RP11-93O14.2		5573	0.18
chr12_3764521_3764672	0.71	EFCAB4B	EF-hand calcium binding domain 4B	1207	0.6
chr11_86107824_86107975	0.71	CCDC81	coiled-coil domain containing 81	1683	0.41
chr5_158521432_158521583	0.71	EBF1	early B-cell factor 1	5194	0.28
chr12_47353443_47353741	0.70	PCED1B	PC-esterase domain containing 1B	119794	0.06
chr2_43186668_43186819	0.70	ENSG00000207087	.	131889	0.05
chr8_133028834_133028985	0.70	OC90	otoconin 90	42718	0.18
chr22_29900076_29900399	0.70	NEFH	neurofilament, heavy polypeptide	24018	0.12
chr11_95293251_95293402	0.70	ENSG00000201204	.	86788	0.1
chr12_6291402_6291664	0.70	CD9	CD9 molecule	17348	0.18
chr6_113754417_113754695	0.70	ENSG00000222677	.	81633	0.11
chr3_138405424_138405575	0.70	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	27829	0.21
chr12_11932326_11932519	0.69	ETV6	ets variant 6	26987	0.25
chr5_123150622_123150773	0.69	CSNK1G3	casein kinase 1, gamma 3	226578	0.02
chr14_105721504_105721672	0.69	BRF1	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	5847	0.17
chr18_54467142_54467293	0.69	ENSG00000206865	.	46660	0.16
chr18_74164240_74164484	0.69	ZNF516	zinc finger protein 516	38373	0.14
chr6_114130369_114130564	0.69	ENSG00000253091	.	27799	0.16
chr3_159898869_159899071	0.69	IL12A-AS1	IL12A antisense RNA 1	25909	0.17
chr2_110679093_110679244	0.68	LIMS3	LIM and senescent cell antigen-like domains 3	22900	0.24
chr14_58798060_58798539	0.68	ARID4A	AT rich interactive domain 4A (RBP1-like)	294	0.86
chr19_32165941_32166092	0.68	ENSG00000252780	.	19649	0.28
chr18_2068827_2069125	0.68	METTL4	methyltransferase like 4	485715	0.0
chr6_123038626_123038777	0.68	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta	5	0.98
chr18_59401590_59401741	0.68	RNF152	ring finger protein 152	159327	0.04
chr11_110019213_110019563	0.68	ZC3H12C	zinc finger CCCH-type containing 12C	12809	0.3
chr12_88756954_88757105	0.67	ENSG00000199245	.	67190	0.14
chr6_140692249_140692400	0.67	ENSG00000263514	.	165935	0.04
chr4_128619641_128619792	0.67	INTU	inturned planar cell polarity protein	10747	0.23
chr4_186488536_186488687	0.67	RP11-301L8.2		20452	0.16
chr5_39399369_39399640	0.67	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	5002	0.29
chr10_79002677_79003016	0.67	RP11-328K22.1		70853	0.11
chr21_39612976_39613250	0.67	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	15550	0.24

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.2	0.5	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.6	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.4	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0042637	catagen(GO:0042637)
0.1	0.6	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	1.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.3	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.4	GO:0051014	actin filament severing(GO:0051014)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.4	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.2	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.1	0.3	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.1	0.6	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.3	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.1	0.4	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.4	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.3	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.3	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.1	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.1	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.3	GO:0001757	somite specification(GO:0001757)
0.1	0.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.1	0.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.1	GO:0031223	auditory behavior(GO:0031223)
0.1	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.1	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.1	0.2	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.2	GO:0007412	axon target recognition(GO:0007412)
0.1	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.1	0.1	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.3	GO:0034405	response to fluid shear stress(GO:0034405)
0.1	0.4	GO:0072678	T cell migration(GO:0072678)
0.1	0.3	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0060900	optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	1.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.4	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.4	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.3	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.5	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.2	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.5	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.2	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.9	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.2	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.4	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.2	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.3	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	1.0	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.3	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.6	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.2	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.3	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.3	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.2	GO:0090504	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.2	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.9	GO:0017157	regulation of exocytosis(GO:0017157)
0.0	0.2	GO:0007143	female meiotic division(GO:0007143)
0.0	0.1	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.4	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.6	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0030185	nitric oxide transport(GO:0030185)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) vein smooth muscle contraction(GO:0014826) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.0	GO:0003099	regulation of the force of heart contraction by chemical signal(GO:0003057) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.5	GO:0030318	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.0	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.3	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0019359	nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.6	GO:0006956	complement activation(GO:0006956)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.1	GO:0051044	regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0043113	receptor clustering(GO:0043113)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.2	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0051324	prophase(GO:0051324)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.3	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.3	GO:0097581	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.2	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.0	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0061462	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0021955	central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.0	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0071326	cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.1	GO:0048241	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0046036	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.0	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.0	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.2	GO:0045740	positive regulation of DNA replication(GO:0045740)
0.0	0.1	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.0	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0060914	heart formation(GO:0060914)
0.0	0.4	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.1	GO:0052646	alditol phosphate metabolic process(GO:0052646)
0.0	0.2	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.2	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.0	GO:0007616	long-term memory(GO:0007616)
0.0	0.0	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.0	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.1	GO:0001759	organ induction(GO:0001759)
0.0	0.0	GO:0071504	cellular response to heparin(GO:0071504)
0.0	0.0	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.0	GO:0071295	cellular response to vitamin(GO:0071295)
0.0	0.1	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0010642	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.0	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0060438	trachea development(GO:0060438)
0.0	0.0	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	0.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.3	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	1.3	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.4	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.2	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.5	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.6	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.3	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	3.3	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.3	0.8	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	1.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.6	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.6	GO:0070063	RNA polymerase binding(GO:0070063)
0.1	0.9	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.7	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.1	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.2	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.1	0.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.2	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.9	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.6	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.7	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.5	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	1.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.4	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.2	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.3	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0019825	oxygen binding(GO:0019825)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0015645	fatty acid ligase activity(GO:0015645)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	1.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0016918	retinal binding(GO:0016918)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	2.9	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.0	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.7	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.6	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	2.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	2.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.1	0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	Genes involved in Insulin receptor signalling cascade
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.5	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.0	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.0	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC

Results for MEF2C

Z-value: 3.34

Motif logo

Transcription factors associated with MEF2C

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MEF2C motif across conditions

Conditions sorted by the z-value of the MEF2C motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: