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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MEF2D_MEF2A

Z-value: 1.45

Motif logo

Transcription factors associated with MEF2D_MEF2A

Gene Symbol	Gene ID	Gene Info
MEF2D Ensembl NCBI GeneCards UniProt	ENSG00000116604.13	MEF2D
MEF2A Ensembl NCBI GeneCards UniProt	ENSG00000068305.13	MEF2A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MEF2A	chr15_100109254_100109609	2743	0.325623	0.77	1.5e-02	Click!
MEF2A	chr15_100027235_100027578	10036	0.204350	0.77	1.5e-02	Click!
MEF2A	chr15_100014464_100014615	2831	0.289011	0.62	7.3e-02	Click!
MEF2A	chr15_100014188_100014339	3107	0.276311	0.59	9.4e-02	Click!
MEF2A	chr15_100017898_100018181	669	0.732407	0.54	1.3e-01	Click!
MEF2D	chr1_156447078_156447229	6069	0.130171	0.59	9.8e-02	Click!
MEF2D	chr1_156482148_156482299	11603	0.112247	0.58	1.0e-01	Click!
MEF2D	chr1_156466400_156466875	3892	0.146775	0.52	1.5e-01	Click!
MEF2D	chr1_156434373_156434524	18774	0.108483	0.51	1.6e-01	Click!
MEF2D	chr1_156434831_156434999	18307	0.109151	0.51	1.6e-01	Click!

Activity of the MEF2D_MEF2A motif across conditions

Conditions sorted by the z-value of the MEF2D_MEF2A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_66050940_66051359	0.73	HMGA2	high mobility group AT-hook 2	166762	0.03
chr11_94661181_94661856	0.63	RP11-856F16.2		2832	0.29
chr6_85293592_85293821	0.61	RP11-132M7.3		105437	0.08
chr6_16903564_16904059	0.57	RP1-151F17.1		141668	0.05
chr18_67996235_67996386	0.55	RP11-41O4.1	Uncharacterized protein	6365	0.22
chr5_77889982_77890133	0.53	LHFPL2	lipoma HMGIC fusion partner-like 2	45083	0.2
chr16_86775300_86775582	0.53	FOXL1	forkhead box L1	163326	0.03
chr14_56777353_56777504	0.52	TMEM260	transmembrane protein 260	177644	0.03
chr11_115488521_115488672	0.52	ENSG00000239153	.	9307	0.31
chr16_11255917_11256068	0.51	CLEC16A	C-type lectin domain family 16, member A	36067	0.13
chr8_97803430_97803993	0.51	CPQ	carboxypeptidase Q	30243	0.25
chr22_29900076_29900399	0.50	NEFH	neurofilament, heavy polypeptide	24018	0.12
chr4_41180087_41180238	0.50	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	36313	0.15
chr9_101803098_101803249	0.50	TGFBR1	transforming growth factor, beta receptor 1	63147	0.11
chr21_43377285_43377631	0.49	C2CD2	C2 calcium-dependent domain containing 2	3459	0.24
chr1_55828154_55828305	0.49	ENSG00000199831	.	14296	0.23
chr16_46782782_46782933	0.48	MYLK3	myosin light chain kinase 3	636	0.74
chr17_1700234_1700385	0.47	SMYD4	SET and MYND domain containing 4	3790	0.15
chr12_15842783_15842934	0.47	ENSG00000200105	.	18114	0.22
chr12_27704088_27704418	0.47	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	13197	0.23
chr1_110121167_110121450	0.46	ENSG00000206832	.	12954	0.08
chr16_48478901_48479413	0.46	RP11-44I10.6		3152	0.22
chr17_74954230_74954498	0.45	ENSG00000267568	.	10815	0.22
chr1_168467710_168467921	0.45	XCL2	chemokine (C motif) ligand 2	45420	0.16
chr12_6335494_6335645	0.44	ENSG00000202318	.	8052	0.18
chr2_178332517_178332770	0.43	AGPS	alkylglycerone phosphate synthase	75147	0.07
chr5_148796784_148796935	0.43	ENSG00000208035	.	11622	0.13
chr2_218766852_218767096	0.42	TNS1	tensin 1	242	0.95
chr16_73200279_73201088	0.42	C16orf47	chromosome 16 open reading frame 47	22337	0.26
chr11_124595331_124595482	0.42	NRGN	neurogranin (protein kinase C substrate, RC3)	14336	0.1
chr2_204553524_204553955	0.41	CD28	CD28 molecule	17459	0.24
chr2_151519523_151519674	0.41	RND3	Rho family GTPase 3	124073	0.06
chr3_149050046_149050197	0.41	TM4SF18	transmembrane 4 L six family member 18	1148	0.5
chr12_66269655_66269806	0.41	RP11-366L20.2	Uncharacterized protein	5628	0.2
chr1_68056079_68056230	0.41	ENSG00000207504	.	49344	0.14
chr22_51016890_51017529	0.41	CPT1B	carnitine palmitoyltransferase 1B (muscle)	113	0.91
chr10_79150619_79150770	0.40	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	13048	0.23
chr16_75086975_75087126	0.40	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	50855	0.11
chr1_68638974_68639247	0.39	ENSG00000221203	.	10183	0.22
chr7_75340828_75341228	0.39	HIP1	huntingtin interacting protein 1	27231	0.18
chr14_105721504_105721672	0.39	BRF1	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	5847	0.17
chr2_216363831_216363982	0.39	AC012462.1		62930	0.13
chr2_43135820_43135971	0.39	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	116163	0.06
chr21_17584166_17584317	0.39	ENSG00000201025	.	72848	0.13
chr15_25916381_25916532	0.39	ATP10A	ATPase, class V, type 10A	23516	0.19
chr2_220299434_220299585	0.39	SPEG	SPEG complex locus	59	0.95
chr2_158697443_158697594	0.39	ACVR1	activin A receptor, type I	2679	0.28
chr11_123992842_123992993	0.39	VWA5A	von Willebrand factor A domain containing 5A	6760	0.19
chr8_17547050_17547201	0.39	ENSG00000265520	.	7959	0.17
chr10_29611883_29612034	0.39	LYZL1	lysozyme-like 1	33968	0.21
chr2_30589074_30589411	0.39	ENSG00000221377	.	66072	0.12
chr6_106589541_106589692	0.38	RP1-134E15.3		41601	0.16
chr7_19064312_19064463	0.38	AC003986.6		87710	0.08
chr17_73869045_73869430	0.38	TRIM47	tripartite motif containing 47	1736	0.17
chr2_193011657_193011808	0.38	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2	47518	0.19
chr9_738221_738372	0.38	KANK1	KN motif and ankyrin repeat domains 1	5680	0.27
chr10_14778717_14778868	0.38	FAM107B	family with sequence similarity 107, member B	38104	0.16
chr18_55957694_55957845	0.37	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	32783	0.18
chr12_108292570_108292721	0.37	ENSG00000263632	.	99148	0.07
chr3_25615486_25615637	0.37	ENSG00000272166	.	18464	0.22
chr6_135045861_135046160	0.37	ALDH8A1	aldehyde dehydrogenase 8 family, member A1	204289	0.02
chr12_11932326_11932519	0.36	ETV6	ets variant 6	26987	0.25
chr4_86747445_86747851	0.36	ARHGAP24	Rho GTPase activating protein 24	1250	0.59
chr7_112124918_112125112	0.36	LSMEM1	leucine-rich single-pass membrane protein 1	3969	0.27
chr1_9473459_9474229	0.36	ENSG00000252956	.	23993	0.2
chr9_84224859_84225018	0.36	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	3499	0.36
chr6_106511937_106512088	0.36	PRDM1	PR domain containing 1, with ZNF domain	22183	0.22
chr6_11211661_11211957	0.36	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	21082	0.2
chr20_43201295_43201704	0.36	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	9691	0.16
chr17_42247977_42248128	0.36	ASB16	ankyrin repeat and SOCS box containing 16	22	0.94
chr1_68212224_68212375	0.35	ENSG00000238778	.	26037	0.19
chr12_107235247_107235617	0.35	RP11-144F15.1	Uncharacterized protein	66736	0.1
chr12_31738710_31738861	0.34	DENND5B-AS1	DENND5B antisense RNA 1	4072	0.18
chr4_186842803_186842954	0.34	ENSG00000239034	.	24359	0.19
chr2_159522500_159522651	0.34	AC005042.4		68755	0.11
chr5_36692406_36692557	0.34	CTD-2353F22.1		32794	0.22
chr9_112871990_112872141	0.34	AKAP2	A kinase (PRKA) anchor protein 2	15716	0.27
chr1_184476924_184477075	0.34	GS1-115G20.1		99528	0.07
chr20_47299343_47299823	0.34	ENSG00000251876	.	56402	0.16
chr5_170922531_170922682	0.33	FGF18	fibroblast growth factor 18	75946	0.09
chr6_108724802_108724953	0.33	ENSG00000200799	.	11600	0.25
chr19_11314159_11314310	0.33	CTC-510F12.2		70	0.94
chr3_45593577_45593808	0.33	ENSG00000251927	.	40055	0.14
chr7_121012833_121012984	0.33	FAM3C	family with sequence similarity 3, member C	23454	0.22
chr2_173258743_173259031	0.33	ITGA6	integrin, alpha 6	33195	0.16
chr5_14210766_14211222	0.32	TRIO	trio Rho guanine nucleotide exchange factor	27087	0.27
chr11_95293251_95293402	0.32	ENSG00000201204	.	86788	0.1
chr2_28556445_28556596	0.31	AC093690.1		23194	0.18
chr2_65138467_65138618	0.31	ENSG00000238696	.	2722	0.24
chr5_167831336_167831487	0.31	WWC1	WW and C2 domain containing 1	1873	0.44
chr3_48597793_48598316	0.31	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	508	0.63
chr17_27946401_27946552	0.31	CORO6	coronin 6	1341	0.21
chr5_95482244_95482395	0.31	ENSG00000206997	.	63612	0.12
chr10_12447179_12447330	0.31	ENSG00000252438	.	10673	0.2
chr11_131926212_131926363	0.30	RP11-697E14.2		71732	0.13
chr3_185499420_185499571	0.30	ENSG00000265470	.	13803	0.21
chr11_27487003_27487154	0.30	RP11-159H22.2		6198	0.18
chr22_27714638_27714789	0.30	ENSG00000200443	.	282863	0.01
chr12_12032698_12032849	0.30	ETV6	ets variant 6	6098	0.32
chr7_129665295_129665446	0.30	ENSG00000201109	.	1747	0.26
chr8_8458649_8458942	0.30	ENSG00000263616	.	18630	0.21
chr4_186629734_186630027	0.30	ENSG00000207497	.	1241	0.48
chr11_2404349_2404515	0.30	CD81	CD81 molecule	742	0.5
chr5_173382092_173382267	0.30	C5orf47	chromosome 5 open reading frame 47	33983	0.18
chr11_96612522_96612673	0.29	ENSG00000200411	.	404741	0.01
chr11_69264083_69264234	0.29	CCND1	cyclin D1	191697	0.03
chr11_3191381_3191561	0.29	OSBPL5	oxysterol binding protein-like 5	4471	0.17
chr6_72253421_72253572	0.29	ENSG00000212099	.	4817	0.27
chr15_67816844_67817150	0.29	C15orf61	chromosome 15 open reading frame 61	2964	0.29
chr20_32978878_32979235	0.29	ENSG00000201498	.	6985	0.16
chr12_49638204_49638355	0.29	TUBA1C	tubulin, alpha 1c	16570	0.11
chr13_75470100_75470251	0.29	ENSG00000206812	.	213549	0.02
chr6_73470213_73470364	0.29	KCNQ5-IT1	KCNQ5 intronic transcript 1 (non-protein coding)	130065	0.05
chr8_8730365_8730844	0.29	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	20551	0.19
chr2_74995599_74995750	0.29	HK2	hexokinase 2	65434	0.1
chr3_177053679_177054041	0.29	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	138599	0.05
chr5_77149047_77149316	0.29	TBCA	tubulin folding cofactor A	15423	0.29
chr7_18545725_18546026	0.28	HDAC9	histone deacetylase 9	3021	0.37
chr4_71503415_71503566	0.28	ENAM	enamelin	9029	0.14
chr1_17945445_17945596	0.28	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	671	0.8
chr8_131307946_131308498	0.28	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	44961	0.19
chr3_107938086_107938657	0.28	IFT57	intraflagellar transport 57 homolog (Chlamydomonas)	2851	0.36
chr11_9350558_9350709	0.28	TMEM41B	transmembrane protein 41B	14306	0.18
chr20_50150448_50150603	0.28	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	8733	0.28
chr6_45486037_45486188	0.28	RUNX2	runt-related transcription factor 2	95890	0.08
chr9_83650488_83650760	0.28	ENSG00000221581	.	301380	0.01
chr16_88448984_88449499	0.28	ZNF469	zinc finger protein 469	44638	0.14
chr20_23132592_23133523	0.28	ENSG00000201527	.	8551	0.22
chr6_82660862_82661141	0.28	ENSG00000206886	.	187260	0.03
chr6_140075001_140075152	0.28	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	379319	0.01
chr1_85224442_85225362	0.28	ENSG00000251899	.	33980	0.18
chr7_50813178_50813329	0.28	GRB10	growth factor receptor-bound protein 10	10503	0.29
chr1_23428113_23428264	0.28	LUZP1	leucine zipper protein 1	7435	0.14
chr1_84945799_84946552	0.27	RPF1	ribosome production factor 1 homolog (S. cerevisiae)	1225	0.46
chr11_128270550_128270701	0.27	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	104664	0.07
chr10_91405210_91405876	0.27	PANK1	pantothenate kinase 1	328	0.49
chr13_91415783_91415934	0.27	ENSG00000251753	.	18265	0.31
chr14_35885344_35885586	0.27	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	11513	0.26
chr1_52421500_52421651	0.27	ENSG00000200839	.	17507	0.13
chr5_79542311_79543080	0.27	ENSG00000239159	.	7287	0.19
chr2_202819063_202819214	0.27	ENSG00000221489	.	1079	0.52
chr9_93954794_93955117	0.27	AUH	AU RNA binding protein/enoyl-CoA hydratase	169222	0.04
chr5_159306421_159306671	0.27	ADRA1B	adrenoceptor alpha 1B	37244	0.2
chr14_75828613_75828919	0.26	RP11-293M10.6		65627	0.09
chr3_17221418_17221569	0.26	ENSG00000252976	.	44279	0.19
chr5_81460698_81461288	0.26	ENSG00000265684	.	86747	0.08
chr6_140204099_140204250	0.26	ENSG00000252107	.	275657	0.02
chr8_16613343_16613494	0.26	ENSG00000264092	.	107587	0.07
chr9_5518413_5518594	0.26	PDCD1LG2	programmed cell death 1 ligand 2	7933	0.25
chr1_112289193_112289344	0.26	FAM212B-AS1	FAM212B antisense RNA 1	6793	0.17
chr4_157866649_157866809	0.26	PDGFC	platelet derived growth factor C	25326	0.2
chr7_129630529_129630680	0.26	ENSG00000263557	.	5017	0.14
chr13_49672637_49672967	0.26	ENSG00000199788	.	3275	0.28
chr2_218715975_218716307	0.26	TNS1	tensin 1	9258	0.27
chr10_98595394_98596081	0.26	LCOR	ligand dependent nuclear receptor corepressor	3000	0.26
chr12_89340554_89340705	0.26	ENSG00000238302	.	335433	0.01
chr4_77491334_77491539	0.26	ENSG00000263445	.	3285	0.21
chr20_50179743_50180109	0.26	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	556	0.85
chr2_189734866_189735017	0.26	AC079613.1		30770	0.2
chr13_51252402_51252553	0.26	DLEU7-AS1	DLEU7 antisense RNA 1	129515	0.05
chr7_55200144_55200295	0.26	EGFR	epidermal growth factor receptor	22679	0.24
chr12_32286981_32287354	0.26	RP11-843B15.2		26705	0.2
chr4_112855406_112855557	0.26	C4orf32	chromosome 4 open reading frame 32	211072	0.02
chr1_61299199_61299350	0.25	NFIA	nuclear factor I/A	31657	0.24
chr5_54776704_54777172	0.25	ENSG00000265135	.	27816	0.18
chr8_133028834_133028985	0.25	OC90	otoconin 90	42718	0.18
chr12_110579233_110579384	0.25	IFT81	intraflagellar transport 81 homolog (Chlamydomonas)	17111	0.22
chr13_111050298_111050449	0.25	ENSG00000238629	.	16179	0.22
chr7_6291353_6291504	0.25	CYTH3	cytohesin 3	20847	0.16
chr7_151191145_151191634	0.25	RHEB	Ras homolog enriched in brain	23766	0.13
chr1_168605918_168606128	0.25	XCL1	chemokine (C motif) ligand 1	60312	0.13
chr6_25179466_25179765	0.25	ENSG00000222373	.	13026	0.19
chr22_47544990_47545141	0.25	ENSG00000221672	.	301262	0.01
chr9_79088043_79088199	0.25	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	13975	0.26
chr6_116732049_116732623	0.25	DSE	dermatan sulfate epimerase	40226	0.11
chr13_21635893_21636207	0.25	LATS2	large tumor suppressor kinase 2	364	0.85
chr8_120566171_120566430	0.25	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	38948	0.19
chr1_61853531_61853682	0.25	NFIA	nuclear factor I/A	16142	0.29
chr4_57275760_57275911	0.25	AC068620.1	Uncharacterized protein	847	0.53
chr5_115789878_115790274	0.25	CTB-118N6.3		4650	0.26
chr9_95243384_95243848	0.25	ASPN	asporin	1172	0.49
chr10_3570543_3570694	0.25	RP11-184A2.3		222641	0.02
chr19_36715300_36715460	0.25	ZNF146	zinc finger protein 146	9345	0.12
chr5_133846467_133846815	0.25	ENSG00000240250	.	6860	0.16
chr10_33260832_33260993	0.25	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	8701	0.27
chr12_13062950_13063285	0.25	GPRC5A	G protein-coupled receptor, family C, group 5, member A	1114	0.4
chr7_12624091_12624305	0.25	SCIN	scinderin	4355	0.26
chr1_206866532_206866832	0.24	MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	8300	0.15
chr1_77862267_77862418	0.24	ENSG00000221664	.	5129	0.23
chr15_25915798_25916253	0.24	ATP10A	ATPase, class V, type 10A	23947	0.19
chr3_16948269_16948754	0.24	PLCL2	phospholipase C-like 2	22059	0.21
chr10_44162371_44162574	0.24	ZNF32	zinc finger protein 32	18168	0.16
chr17_36577454_36577813	0.24	ARHGAP23	Rho GTPase activating protein 23	7029	0.16
chr17_41327708_41328475	0.24	NBR1	neighbor of BRCA1 gene 1	4831	0.16
chr10_80861964_80862203	0.24	ZMIZ1	zinc finger, MIZ-type containing 1	33291	0.19
chr1_201729154_201729305	0.24	NAV1	neuron navigator 1	20233	0.11
chr2_155312519_155312670	0.24	AC009227.2		1356	0.52
chr9_116355859_116356115	0.24	RGS3	regulator of G-protein signaling 3	221	0.94
chr12_42841401_42841552	0.24	ENSG00000207142	.	7046	0.16
chr3_189766577_189766728	0.24	ENSG00000265045	.	65071	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0051014	actin filament severing(GO:0051014)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.4	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.2	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:1903224	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.0	GO:1903670	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.0	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.2	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.0	GO:0090267	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.1	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.0	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0070091	glucagon secretion(GO:0070091)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.4	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival