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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MEF2D_MEF2A

Z-value: 1.45

Motif logo

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.13 myocyte enhancer factor 2D
MEF2A
ENSG00000068305.13 myocyte enhancer factor 2A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr15_100109254_100109609MEF2A27430.3256230.771.5e-02Click!
chr15_100027235_100027578MEF2A100360.2043500.771.5e-02Click!
chr15_100014464_100014615MEF2A28310.2890110.627.3e-02Click!
chr15_100014188_100014339MEF2A31070.2763110.599.4e-02Click!
chr15_100017898_100018181MEF2A6690.7324070.541.3e-01Click!
chr1_156447078_156447229MEF2D60690.1301710.599.8e-02Click!
chr1_156482148_156482299MEF2D116030.1122470.581.0e-01Click!
chr1_156466400_156466875MEF2D38920.1467750.521.5e-01Click!
chr1_156434373_156434524MEF2D187740.1084830.511.6e-01Click!
chr1_156434831_156434999MEF2D183070.1091510.511.6e-01Click!

Activity of the MEF2D_MEF2A motif across conditions

Conditions sorted by the z-value of the MEF2D_MEF2A motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_66050940_66051359 0.73 HMGA2
 high mobility group AT-hook 2
 166762
 0.03
chr11_94661181_94661856 0.63 RP11-856F16.2
2832
 0.29
chr6_85293592_85293821 0.61 RP11-132M7.3
105437
 0.08
chr6_16903564_16904059 0.57 RP1-151F17.1
141668
 0.05
chr18_67996235_67996386 0.55 RP11-41O4.1
 Uncharacterized protein
 6365
 0.22
chr5_77889982_77890133 0.53 LHFPL2
 lipoma HMGIC fusion partner-like 2
 45083
 0.2
chr16_86775300_86775582 0.53 FOXL1
 forkhead box L1
 163326
 0.03
chr14_56777353_56777504 0.52 TMEM260
 transmembrane protein 260
 177644
 0.03
chr11_115488521_115488672 0.52 ENSG00000239153
 .
 9307
 0.31
chr16_11255917_11256068 0.51 CLEC16A
 C-type lectin domain family 16, member A
 36067
 0.13
chr8_97803430_97803993 0.51 CPQ
 carboxypeptidase Q
 30243
 0.25
chr22_29900076_29900399 0.50 NEFH
 neurofilament, heavy polypeptide
 24018
 0.12
chr4_41180087_41180238 0.50 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 36313
 0.15
chr9_101803098_101803249 0.50 TGFBR1
 transforming growth factor, beta receptor 1
 63147
 0.11
chr21_43377285_43377631 0.49 C2CD2
 C2 calcium-dependent domain containing 2
 3459
 0.24
chr1_55828154_55828305 0.49 ENSG00000199831
 .
 14296
 0.23
chr16_46782782_46782933 0.48 MYLK3
 myosin light chain kinase 3
 636
 0.74
chr17_1700234_1700385 0.47 SMYD4
 SET and MYND domain containing 4
 3790
 0.15
chr12_15842783_15842934 0.47 ENSG00000200105
 .
 18114
 0.22
chr12_27704088_27704418 0.47 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
 13197
 0.23
chr1_110121167_110121450 0.46 ENSG00000206832
 .
 12954
 0.08
chr16_48478901_48479413 0.46 RP11-44I10.6
3152
 0.22
chr17_74954230_74954498 0.45 ENSG00000267568
 .
 10815
 0.22
chr1_168467710_168467921 0.45 XCL2
 chemokine (C motif) ligand 2
 45420
 0.16
chr12_6335494_6335645 0.44 ENSG00000202318
 .
 8052
 0.18
chr2_178332517_178332770 0.43 AGPS
 alkylglycerone phosphate synthase
 75147
 0.07
chr5_148796784_148796935 0.43 ENSG00000208035
 .
 11622
 0.13
chr2_218766852_218767096 0.42 TNS1
 tensin 1
 242
 0.95
chr16_73200279_73201088 0.42 C16orf47
 chromosome 16 open reading frame 47
 22337
 0.26
chr11_124595331_124595482 0.42 NRGN
 neurogranin (protein kinase C substrate, RC3)
 14336
 0.1
chr2_204553524_204553955 0.41 CD28
 CD28 molecule
 17459
 0.24
chr2_151519523_151519674 0.41 RND3
 Rho family GTPase 3
 124073
 0.06
chr3_149050046_149050197 0.41 TM4SF18
 transmembrane 4 L six family member 18
 1148
 0.5
chr12_66269655_66269806 0.41 RP11-366L20.2
 Uncharacterized protein
 5628
 0.2
chr1_68056079_68056230 0.41 ENSG00000207504
 .
 49344
 0.14
chr22_51016890_51017529 0.41 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
 113
 0.91
chr10_79150619_79150770 0.40 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 13048
 0.23
chr16_75086975_75087126 0.40 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 50855
 0.11
chr1_68638974_68639247 0.39 ENSG00000221203
 .
 10183
 0.22
chr7_75340828_75341228 0.39 HIP1
 huntingtin interacting protein 1
 27231
 0.18
chr14_105721504_105721672 0.39 BRF1
 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
 5847
 0.17
chr2_216363831_216363982 0.39 AC012462.1
62930
 0.13
chr2_43135820_43135971 0.39 HAAO
 3-hydroxyanthranilate 3,4-dioxygenase
 116163
 0.06
chr21_17584166_17584317 0.39 ENSG00000201025
 .
 72848
 0.13
chr15_25916381_25916532 0.39 ATP10A
 ATPase, class V, type 10A
 23516
 0.19
chr2_220299434_220299585 0.39 SPEG
 SPEG complex locus
 59
 0.95
chr2_158697443_158697594 0.39 ACVR1
 activin A receptor, type I
 2679
 0.28
chr11_123992842_123992993 0.39 VWA5A
 von Willebrand factor A domain containing 5A
 6760
 0.19
chr8_17547050_17547201 0.39 ENSG00000265520
 .
 7959
 0.17
chr10_29611883_29612034 0.39 LYZL1
 lysozyme-like 1
 33968
 0.21
chr2_30589074_30589411 0.39 ENSG00000221377
 .
 66072
 0.12
chr6_106589541_106589692 0.38 RP1-134E15.3
41601
 0.16
chr7_19064312_19064463 0.38 AC003986.6
87710
 0.08
chr17_73869045_73869430 0.38 TRIM47
 tripartite motif containing 47
 1736
 0.17
chr2_193011657_193011808 0.38 TMEFF2
 transmembrane protein with EGF-like and two follistatin-like domains 2
 47518
 0.19
chr9_738221_738372 0.38 KANK1
 KN motif and ankyrin repeat domains 1
 5680
 0.27
chr10_14778717_14778868 0.38 FAM107B
 family with sequence similarity 107, member B
 38104
 0.16
chr18_55957694_55957845 0.37 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 32783
 0.18
chr12_108292570_108292721 0.37 ENSG00000263632
 .
 99148
 0.07
chr3_25615486_25615637 0.37 ENSG00000272166
 .
 18464
 0.22
chr6_135045861_135046160 0.37 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
 204289
 0.02
chr12_11932326_11932519 0.36 ETV6
 ets variant 6
 26987
 0.25
chr4_86747445_86747851 0.36 ARHGAP24
 Rho GTPase activating protein 24
 1250
 0.59
chr7_112124918_112125112 0.36 LSMEM1
 leucine-rich single-pass membrane protein 1
 3969
 0.27
chr1_9473459_9474229 0.36 ENSG00000252956
 .
 23993
 0.2
chr9_84224859_84225018 0.36 TLE1
 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
 3499
 0.36
chr6_106511937_106512088 0.36 PRDM1
 PR domain containing 1, with ZNF domain
 22183
 0.22
chr6_11211661_11211957 0.36 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 21082
 0.2
chr20_43201295_43201704 0.36 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
 9691
 0.16
chr17_42247977_42248128 0.36 ASB16
 ankyrin repeat and SOCS box containing 16
 22
 0.94
chr1_68212224_68212375 0.35 ENSG00000238778
 .
 26037
 0.19
chr12_107235247_107235617 0.35 RP11-144F15.1
 Uncharacterized protein
 66736
 0.1
chr12_31738710_31738861 0.34 DENND5B-AS1
 DENND5B antisense RNA 1
 4072
 0.18
chr4_186842803_186842954 0.34 ENSG00000239034
 .
 24359
 0.19
chr2_159522500_159522651 0.34 AC005042.4
68755
 0.11
chr5_36692406_36692557 0.34 CTD-2353F22.1
32794
 0.22
chr9_112871990_112872141 0.34 AKAP2
 A kinase (PRKA) anchor protein 2
 15716
 0.27
chr1_184476924_184477075 0.34 GS1-115G20.1
99528
 0.07
chr20_47299343_47299823 0.34 ENSG00000251876
 .
 56402
 0.16
chr5_170922531_170922682 0.33 FGF18
 fibroblast growth factor 18
 75946
 0.09
chr6_108724802_108724953 0.33 ENSG00000200799
 .
 11600
 0.25
chr19_11314159_11314310 0.33 CTC-510F12.2
70
 0.94
chr3_45593577_45593808 0.33 ENSG00000251927
 .
 40055
 0.14
chr7_121012833_121012984 0.33 FAM3C
 family with sequence similarity 3, member C
 23454
 0.22
chr2_173258743_173259031 0.33 ITGA6
 integrin, alpha 6
 33195
 0.16
chr5_14210766_14211222 0.32 TRIO
 trio Rho guanine nucleotide exchange factor
 27087
 0.27
chr11_95293251_95293402 0.32 ENSG00000201204
 .
 86788
 0.1
chr2_28556445_28556596 0.31 AC093690.1
23194
 0.18
chr2_65138467_65138618 0.31 ENSG00000238696
 .
 2722
 0.24
chr5_167831336_167831487 0.31 WWC1
 WW and C2 domain containing 1
 1873
 0.44
chr3_48597793_48598316 0.31 PFKFB4
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
 508
 0.63
chr17_27946401_27946552 0.31 CORO6
 coronin 6
 1341
 0.21
chr5_95482244_95482395 0.31 ENSG00000206997
 .
 63612
 0.12
chr10_12447179_12447330 0.31 ENSG00000252438
 .
 10673
 0.2
chr11_131926212_131926363 0.30 RP11-697E14.2
71732
 0.13
chr3_185499420_185499571 0.30 ENSG00000265470
 .
 13803
 0.21
chr11_27487003_27487154 0.30 RP11-159H22.2
6198
 0.18
chr22_27714638_27714789 0.30 ENSG00000200443
 .
 282863
 0.01
chr12_12032698_12032849 0.30 ETV6
 ets variant 6
 6098
 0.32
chr7_129665295_129665446 0.30 ENSG00000201109
 .
 1747
 0.26
chr8_8458649_8458942 0.30 ENSG00000263616
 .
 18630
 0.21
chr4_186629734_186630027 0.30 ENSG00000207497
 .
 1241
 0.48
chr11_2404349_2404515 0.30 CD81
 CD81 molecule
 742
 0.5
chr5_173382092_173382267 0.30 C5orf47
 chromosome 5 open reading frame 47
 33983
 0.18
chr11_96612522_96612673 0.29 ENSG00000200411
 .
 404741
 0.01
chr11_69264083_69264234 0.29 CCND1
 cyclin D1
 191697
 0.03
chr11_3191381_3191561 0.29 OSBPL5
 oxysterol binding protein-like 5
 4471
 0.17
chr6_72253421_72253572 0.29 ENSG00000212099
 .
 4817
 0.27
chr15_67816844_67817150 0.29 C15orf61
 chromosome 15 open reading frame 61
 2964
 0.29
chr20_32978878_32979235 0.29 ENSG00000201498
 .
 6985
 0.16
chr12_49638204_49638355 0.29 TUBA1C
 tubulin, alpha 1c
 16570
 0.11
chr13_75470100_75470251 0.29 ENSG00000206812
 .
 213549
 0.02
chr6_73470213_73470364 0.29 KCNQ5-IT1
 KCNQ5 intronic transcript 1 (non-protein coding)
 130065
 0.05
chr8_8730365_8730844 0.29 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 20551
 0.19
chr2_74995599_74995750 0.29 HK2
 hexokinase 2
 65434
 0.1
chr3_177053679_177054041 0.29 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 138599
 0.05
chr5_77149047_77149316 0.29 TBCA
 tubulin folding cofactor A
 15423
 0.29
chr7_18545725_18546026 0.28 HDAC9
 histone deacetylase 9
 3021
 0.37
chr4_71503415_71503566 0.28 ENAM
 enamelin
 9029
 0.14
chr1_17945445_17945596 0.28 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 671
 0.8
chr8_131307946_131308498 0.28 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 44961
 0.19
chr3_107938086_107938657 0.28 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
 2851
 0.36
chr11_9350558_9350709 0.28 TMEM41B
 transmembrane protein 41B
 14306
 0.18
chr20_50150448_50150603 0.28 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 8733
 0.28
chr6_45486037_45486188 0.28 RUNX2
 runt-related transcription factor 2
 95890
 0.08
chr9_83650488_83650760 0.28 ENSG00000221581
 .
 301380
 0.01
chr16_88448984_88449499 0.28 ZNF469
 zinc finger protein 469
 44638
 0.14
chr20_23132592_23133523 0.28 ENSG00000201527
 .
 8551
 0.22
chr6_82660862_82661141 0.28 ENSG00000206886
 .
 187260
 0.03
chr6_140075001_140075152 0.28 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 379319
 0.01
chr1_85224442_85225362 0.28 ENSG00000251899
 .
 33980
 0.18
chr7_50813178_50813329 0.28 GRB10
 growth factor receptor-bound protein 10
 10503
 0.29
chr1_23428113_23428264 0.28 LUZP1
 leucine zipper protein 1
 7435
 0.14
chr1_84945799_84946552 0.27 RPF1
 ribosome production factor 1 homolog (S. cerevisiae)
 1225
 0.46
chr11_128270550_128270701 0.27 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 104664
 0.07
chr10_91405210_91405876 0.27 PANK1
 pantothenate kinase 1
 328
 0.49
chr13_91415783_91415934 0.27 ENSG00000251753
 .
 18265
 0.31
chr14_35885344_35885586 0.27 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 11513
 0.26
chr1_52421500_52421651 0.27 ENSG00000200839
 .
 17507
 0.13
chr5_79542311_79543080 0.27 ENSG00000239159
 .
 7287
 0.19
chr2_202819063_202819214 0.27 ENSG00000221489
 .
 1079
 0.52
chr9_93954794_93955117 0.27 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 169222
 0.04
chr5_159306421_159306671 0.27 ADRA1B
 adrenoceptor alpha 1B
 37244
 0.2
chr14_75828613_75828919 0.26 RP11-293M10.6
65627
 0.09
chr3_17221418_17221569 0.26 ENSG00000252976
 .
 44279
 0.19
chr5_81460698_81461288 0.26 ENSG00000265684
 .
 86747
 0.08
chr6_140204099_140204250 0.26 ENSG00000252107
 .
 275657
 0.02
chr8_16613343_16613494 0.26 ENSG00000264092
 .
 107587
 0.07
chr9_5518413_5518594 0.26 PDCD1LG2
 programmed cell death 1 ligand 2
 7933
 0.25
chr1_112289193_112289344 0.26 FAM212B-AS1
 FAM212B antisense RNA 1
 6793
 0.17
chr4_157866649_157866809 0.26 PDGFC
 platelet derived growth factor C
 25326
 0.2
chr7_129630529_129630680 0.26 ENSG00000263557
 .
 5017
 0.14
chr13_49672637_49672967 0.26 ENSG00000199788
 .
 3275
 0.28
chr2_218715975_218716307 0.26 TNS1
 tensin 1
 9258
 0.27
chr10_98595394_98596081 0.26 LCOR
 ligand dependent nuclear receptor corepressor
 3000
 0.26
chr12_89340554_89340705 0.26 ENSG00000238302
 .
 335433
 0.01
chr4_77491334_77491539 0.26 ENSG00000263445
 .
 3285
 0.21
chr20_50179743_50180109 0.26 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 556
 0.85
chr2_189734866_189735017 0.26 AC079613.1
30770
 0.2
chr13_51252402_51252553 0.26 DLEU7-AS1
 DLEU7 antisense RNA 1
 129515
 0.05
chr7_55200144_55200295 0.26 EGFR
 epidermal growth factor receptor
 22679
 0.24
chr12_32286981_32287354 0.26 RP11-843B15.2
26705
 0.2
chr4_112855406_112855557 0.26 C4orf32
 chromosome 4 open reading frame 32
 211072
 0.02
chr1_61299199_61299350 0.25 NFIA
 nuclear factor I/A
 31657
 0.24
chr5_54776704_54777172 0.25 ENSG00000265135
 .
 27816
 0.18
chr8_133028834_133028985 0.25 OC90
 otoconin 90
 42718
 0.18
chr12_110579233_110579384 0.25 IFT81
 intraflagellar transport 81 homolog (Chlamydomonas)
 17111
 0.22
chr13_111050298_111050449 0.25 ENSG00000238629
 .
 16179
 0.22
chr7_6291353_6291504 0.25 CYTH3
 cytohesin 3
 20847
 0.16
chr7_151191145_151191634 0.25 RHEB
 Ras homolog enriched in brain
 23766
 0.13
chr1_168605918_168606128 0.25 XCL1
 chemokine (C motif) ligand 1
 60312
 0.13
chr6_25179466_25179765 0.25 ENSG00000222373
 .
 13026
 0.19
chr22_47544990_47545141 0.25 ENSG00000221672
 .
 301262
 0.01
chr9_79088043_79088199 0.25 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
 13975
 0.26
chr6_116732049_116732623 0.25 DSE
 dermatan sulfate epimerase
 40226
 0.11
chr13_21635893_21636207 0.25 LATS2
 large tumor suppressor kinase 2
 364
 0.85
chr8_120566171_120566430 0.25 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 38948
 0.19
chr1_61853531_61853682 0.25 NFIA
 nuclear factor I/A
 16142
 0.29
chr4_57275760_57275911 0.25 AC068620.1
 Uncharacterized protein
 847
 0.53
chr5_115789878_115790274 0.25 CTB-118N6.3
4650
 0.26
chr9_95243384_95243848 0.25 ASPN
 asporin
 1172
 0.49
chr10_3570543_3570694 0.25 RP11-184A2.3
222641
 0.02
chr19_36715300_36715460 0.25 ZNF146
 zinc finger protein 146
 9345
 0.12
chr5_133846467_133846815 0.25 ENSG00000240250
 .
 6860
 0.16
chr10_33260832_33260993 0.25 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 8701
 0.27
chr12_13062950_13063285 0.25 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 1114
 0.4
chr7_12624091_12624305 0.25 SCIN
 scinderin
 4355
 0.26
chr1_206866532_206866832 0.24 MAPKAPK2
 mitogen-activated protein kinase-activated protein kinase 2
 8300
 0.15
chr1_77862267_77862418 0.24 ENSG00000221664
 .
 5129
 0.23
chr15_25915798_25916253 0.24 ATP10A
 ATPase, class V, type 10A
 23947
 0.19
chr3_16948269_16948754 0.24 PLCL2
 phospholipase C-like 2
 22059
 0.21
chr10_44162371_44162574 0.24 ZNF32
 zinc finger protein 32
 18168
 0.16
chr17_36577454_36577813 0.24 ARHGAP23
 Rho GTPase activating protein 23
 7029
 0.16
chr17_41327708_41328475 0.24 NBR1
 neighbor of BRCA1 gene 1
 4831
 0.16
chr10_80861964_80862203 0.24 ZMIZ1
 zinc finger, MIZ-type containing 1
 33291
 0.19
chr1_201729154_201729305 0.24 NAV1
 neuron navigator 1
 20233
 0.11
chr2_155312519_155312670 0.24 AC009227.2
1356
 0.52
chr9_116355859_116356115 0.24 RGS3
 regulator of G-protein signaling 3
 221
 0.94
chr12_42841401_42841552 0.24 ENSG00000207142
 .
 7046
 0.16
chr3_189766577_189766728 0.24 ENSG00000265045
 .
 65071
 0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.4 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0042637 catagen(GO:0042637)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.2 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0090281 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:1903670 regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0 0.0 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.0 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.0 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival