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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for MEIS2

Z-value: 1.62

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Transcription factors associated with MEIS2

Gene Symbol	Gene ID	Gene Info
MEIS2 Ensembl NCBI GeneCards UniProt	ENSG00000134138.15	Meis homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_37387462_37387763	MEIS2	390	0.871649	-0.87	2.0e-03	Click!
chr15_37402971_37403122	MEIS2	9542	0.226269	-0.85	4.0e-03	Click!
chr15_37402742_37402893	MEIS2	9313	0.226705	-0.84	4.4e-03	Click!
chr15_37394546_37394764	MEIS2	1151	0.518203	-0.77	1.6e-02	Click!
chr15_37390143_37390314	MEIS2	275	0.883031	-0.72	2.8e-02	Click!

Activity of the MEIS2 motif across conditions

Conditions sorted by the z-value of the MEIS2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrY_117140_117541	2.20	NA	NA	> 10⁶	NA
chr17_78845626_78846398	1.86	RPTOR	regulatory associated protein of MTOR, complex 1	50512	0.1
chr17_76875045_76875748	1.31	TIMP2	TIMP metallopeptidase inhibitor 2	5164	0.16
chr12_121678757_121679425	1.29	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta	19254	0.17
chr10_76672520_76672974	1.09	KAT6B	K(lysine) acetyltransferase 6B	74289	0.1
chr20_8380540_8381084	0.99	PLCB1-IT1	PLCB1 intronic transcript 1 (non-protein coding)	151440	0.04
chr11_68319868_68320209	0.91	PPP6R3	protein phosphatase 6, regulatory subunit 3	6072	0.21
chr10_114139672_114139929	0.91	ACSL5	acyl-CoA synthetase long-chain family member 5	3843	0.23
chrX_167199_167448	0.90	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1	25666	0.23
chr22_40642780_40643209	0.90	TNRC6B	trinucleotide repeat containing 6B	18013	0.23
chr8_22499257_22499720	0.89	BIN3	bridging integrator 3	2829	0.16
chr6_159125474_159126340	0.88	SYTL3	synaptotagmin-like 3	41712	0.13
chr16_29129607_29129944	0.86	CTB-134H23.3		11009	0.16
chr8_125575470_125576116	0.85	MTSS1	metastasis suppressor 1	2175	0.26
chr6_170404847_170405519	0.84	RP11-302L19.1		72558	0.11
chr15_50392799_50393114	0.84	ATP8B4	ATPase, class I, type 8B, member 4	13745	0.23
chr3_196368477_196368981	0.83	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	2083	0.21
chr8_21766211_21767399	0.83	DOK2	docking protein 2, 56kDa	4369	0.22
chr10_51503867_51504211	0.83	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	17712	0.18
chr18_2883602_2883982	0.81	EMILIN2	elastin microfibril interfacer 2	36764	0.11
chr17_72008045_72008710	0.81	RPL38	ribosomal protein L38	191344	0.02
chr3_16551168_16551938	0.80	RFTN1	raftlin, lipid raft linker 1	2858	0.36
chr11_587585_588264	0.80	PHRF1	PHD and ring finger domains 1	11403	0.07
chr12_68841133_68841474	0.80	MDM1	Mdm1 nuclear protein homolog (mouse)	115142	0.06
chr3_141218689_141219075	0.80	RASA2	RAS p21 protein activator 2	12991	0.21
chr12_65043801_65044168	0.80	RP11-338E21.3		4815	0.15
chr20_39510251_39510483	0.79	ENSG00000238908	.	27498	0.24
chr11_4006180_4006517	0.78	STIM1	stromal interaction molecule 1	37775	0.14
chr11_129988351_129988943	0.78	ST14	suppression of tumorigenicity 14 (colon carcinoma)	40810	0.15
chr2_241504090_241504573	0.78	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	890	0.44
chr9_37486177_37486967	0.78	POLR1E	polymerase (RNA) I polypeptide E, 53kDa	422	0.8
chr2_136814753_136815076	0.78	AC093391.2		44879	0.15
chr14_98689187_98689819	0.77	ENSG00000222066	.	108584	0.07
chrX_1689699_1690290	0.77	AKAP17A	A kinase (PRKA) anchor protein 17A	20492	0.18
chr17_19273582_19274475	0.77	MAPK7	mitogen-activated protein kinase 7	7006	0.11
chr5_169232621_169233022	0.77	CTB-37A13.1		26452	0.22
chr21_36800534_36801386	0.76	ENSG00000211590	.	292053	0.01
chr11_3918269_3918516	0.76	STIM1	stromal interaction molecule 1	6301	0.14
chr9_4596503_4596823	0.75	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	24328	0.19
chr5_96232467_96233018	0.75	ERAP2	endoplasmic reticulum aminopeptidase 2	7821	0.17
chr14_91718270_91718619	0.73	GPR68	G protein-coupled receptor 68	1780	0.32
chr16_30470032_30470581	0.73	ENSG00000202476	.	4888	0.07
chr6_37891842_37892090	0.73	ZFAND3	zinc finger, AN1-type domain 3	5769	0.23
chr9_129285864_129286127	0.73	ENSG00000221768	.	7275	0.22
chr7_102069746_102070456	0.73	ORAI2	ORAI calcium release-activated calcium modulator 2	3452	0.11
chr18_60880832_60881273	0.72	ENSG00000238988	.	19154	0.21
chr9_112827201_112827453	0.72	AKAP2	A kinase (PRKA) anchor protein 2	16351	0.27
chr2_10521424_10521869	0.72	HPCAL1	hippocalcin-like 1	38501	0.14
chr11_68272006_68272464	0.71	ENSG00000222339	.	884	0.48
chr1_156477763_156478531	0.71	MEF2D	myocyte enhancer factor 2D	7527	0.12
chr8_22562900_22563666	0.70	EGR3	early growth response 3	12468	0.13
chr17_74265724_74266071	0.70	UBALD2	UBA-like domain containing 2	4113	0.15
chr2_70331989_70332203	0.69	PCBP1-AS1	PCBP1 antisense RNA 1	16118	0.15
chr11_1145070_1145742	0.69	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	6174	0.2
chr8_37132456_37132991	0.69	RP11-150O12.6		241816	0.02
chr14_100568508_100568904	0.69	EVL	Enah/Vasp-like	5422	0.14
chr7_139922545_139922896	0.68	ENSG00000199971	.	13249	0.16
chr17_57442435_57442935	0.68	ENSG00000263857	.	759	0.63
chr22_24830948_24831363	0.68	ADORA2A	adenosine A2a receptor	2347	0.28
chr3_66534161_66534516	0.68	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	17018	0.29
chr19_14486268_14486999	0.67	CD97	CD97 molecule	5335	0.16
chr6_10413127_10413925	0.66	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	414	0.77
chr2_242067669_242067932	0.66	PASK	PAS domain containing serine/threonine kinase	11210	0.14
chr10_12636480_12636937	0.66	ENSG00000263584	.	15956	0.26
chr6_3026729_3027148	0.66	RP1-90J20.11		1913	0.25
chr9_77765507_77765901	0.66	ENSG00000200041	.	30833	0.16
chr3_23935568_23935872	0.66	RPL15	ribosomal protein L15	22316	0.17
chr1_2174913_2175173	0.66	SKI	v-ski avian sarcoma viral oncogene homolog	14909	0.12
chr16_29611332_29612125	0.66	ENSG00000266758	.	1142	0.43
chr2_145266955_145267602	0.65	ZEB2	zinc finger E-box binding homeobox 2	7837	0.25
chr6_111880308_111880661	0.65	TRAF3IP2-AS1	TRAF3IP2 antisense RNA 1	5970	0.19
chr7_50354105_50354370	0.65	IKZF1	IKAROS family zinc finger 1 (Ikaros)	5919	0.31
chr2_3246663_3247121	0.65	TSSC1-IT1	TSSC1 intronic transcript 1 (non-protein coding)	58344	0.14
chr9_92151633_92152777	0.65	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	39160	0.16
chrX_128888588_128889150	0.64	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	15871	0.19
chr4_4462962_4463617	0.64	STX18	syntaxin 18	392	0.87
chr3_197574613_197575155	0.64	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	12	0.98
chr3_71103539_71103766	0.64	FOXP1	forkhead box P1	10425	0.31
chr4_122111518_122111869	0.64	ENSG00000252183	.	2365	0.34
chr10_104408471_104409659	0.64	TRIM8	tripartite motif containing 8	4421	0.2
chr11_48025895_48026348	0.64	AC103828.1		11286	0.2
chr17_73061461_73061965	0.64	KCTD2	potassium channel tetramerization domain containing 2	18373	0.07
chr5_169714509_169715053	0.63	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	10450	0.22
chr16_30483819_30483970	0.63	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	85	0.88
chr12_15803315_15803614	0.63	EPS8	epidermal growth factor receptor pathway substrate 8	11744	0.22
chr19_16483828_16484062	0.63	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	11181	0.14
chr19_16228666_16229162	0.63	RAB8A	RAB8A, member RAS oncogene family	6207	0.14
chr12_662501_663191	0.63	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3	10547	0.16
chr9_116278367_116278657	0.63	RGS3	regulator of G-protein signaling 3	1038	0.59
chr2_37847075_37847226	0.63	AC006369.2		19871	0.22
chr3_99792803_99793269	0.62	FILIP1L	filamin A interacting protein 1-like	40321	0.15
chr13_100072786_100073153	0.62	ENSG00000266207	.	32754	0.16
chr10_134235955_134236340	0.62	RP11-432J24.3		18841	0.16
chr16_57564544_57565110	0.62	CCDC102A	coiled-coil domain containing 102A	5684	0.15
chr18_60804974_60805454	0.62	RP11-299P2.1		13339	0.24
chr14_93122585_93123047	0.62	RIN3	Ras and Rab interactor 3	3970	0.31
chr13_99935557_99935841	0.62	GPR18	G protein-coupled receptor 18	21701	0.17
chr11_326229_326864	0.62	IFITM3	interferon induced transmembrane protein 3	991	0.28
chr17_36884755_36885077	0.62	AC006449.1	NS5ATP13TP1; Uncharacterized protein	465	0.53
chr6_2901195_2901808	0.62	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	2013	0.31
chr21_36345967_36346246	0.62	RUNX1	runt-related transcription factor 1	75356	0.12
chr16_1609129_1609769	0.62	LA16c-425C2.1		20860	0.08
chr2_42106310_42106729	0.62	ENSG00000223245	.	8108	0.23
chr9_130789038_130789532	0.61	RP11-379C10.1		30356	0.08
chr22_30059316_30059467	0.61	RP1-76B20.12		56312	0.08
chr1_249116365_249116887	0.61	ENSG00000264500	.	3950	0.17
chrX_13068365_13068668	0.61	FAM9C	family with sequence similarity 9, member C	5715	0.29
chr10_33208774_33208970	0.61	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	11441	0.29
chr10_6390281_6390901	0.61	DKFZP667F0711		1687	0.47
chr10_76660118_76660645	0.61	KAT6B	K(lysine) acetyltransferase 6B	61923	0.13
chr10_14639310_14639675	0.61	FAM107B	family with sequence similarity 107, member B	6896	0.24
chr2_27297539_27298497	0.61	OST4	oligosaccharyltransferase 4 homolog (S. cerevisiae)	3377	0.09
chr16_84551314_84551501	0.61	TLDC1	TBC/LysM-associated domain containing 1	13043	0.17
chr1_209932210_209932881	0.60	TRAF3IP3	TRAF3 interacting protein 3	702	0.6
chr1_168482288_168482558	0.60	XCL2	chemokine (C motif) ligand 2	30812	0.2
chr20_44712187_44712338	0.60	NCOA5	nuclear receptor coactivator 5	6329	0.17
chr13_99156494_99156904	0.60	STK24	serine/threonine kinase 24	14822	0.22
chr18_43268528_43268819	0.60	SLC14A2	solute carrier family 14 (urea transporter), member 2	22566	0.17
chr1_90117224_90117495	0.60	LRRC8C	leucine rich repeat containing 8 family, member C	18728	0.16
chrX_109941851_109942119	0.60	CHRDL1	chordin-like 1	97008	0.09
chr10_51499020_51499441	0.60	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	12903	0.2
chr9_21558528_21559235	0.60	MIR31HG	MIR31 host gene (non-protein coding)	787	0.64
chr1_95223071_95223415	0.60	ENSG00000263526	.	11787	0.24
chr19_16555192_16555446	0.59	CTD-2013N17.4		3562	0.16
chr4_2299878_2300029	0.59	RP11-478C1.7		2642	0.2
chr19_18414911_18415207	0.59	LSM4	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)	12010	0.09
chr4_25845411_25845804	0.59	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)	16646	0.24
chr7_44804340_44804491	0.59	ZMIZ2	zinc finger, MIZ-type containing 2	8611	0.16
chr8_128990046_128990302	0.59	ENSG00000221771	.	17295	0.16
chr11_36112461_36112922	0.59	ENSG00000263389	.	81043	0.09
chr16_68117516_68117708	0.59	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	1635	0.23
chr2_161329613_161329866	0.59	RBMS1	RNA binding motif, single stranded interacting protein 1	20290	0.24
chr17_57733680_57734015	0.59	CLTC	clathrin, heavy chain (Hc)	27420	0.15
chrX_13735290_13735441	0.59	TRAPPC2	trafficking protein particle complex 2	17310	0.16
chr1_226840930_226841348	0.59	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	6232	0.23
chr14_102323762_102323913	0.58	CTD-2017C7.1		17969	0.16
chr16_17441111_17441650	0.58	XYLT1	xylosyltransferase I	123358	0.06
chr17_19993225_19993666	0.58	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	3110	0.28
chr20_32119885_32120303	0.58	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	30046	0.15
chr15_40548529_40548680	0.58	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	3219	0.13
chr2_241560209_241560581	0.58	GPR35	G protein-coupled receptor 35	4267	0.16
chr19_16448880_16449487	0.58	KLF2	Kruppel-like factor 2	13532	0.14
chr8_116661022_116661259	0.58	TRPS1	trichorhinophalangeal syndrome I	12765	0.31
chr22_24841252_24841667	0.58	ADORA2A	adenosine A2a receptor	12651	0.16
chr6_166900667_166901285	0.58	ENSG00000222958	.	21945	0.16
chr6_154692239_154692666	0.58	IPCEF1	interaction protein for cytohesin exchange factors 1	14526	0.27
chr7_27004125_27004483	0.58	SKAP2	src kinase associated phosphoprotein 2	30554	0.16
chr10_6182182_6182929	0.57	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	4326	0.16
chr3_14274255_14274511	0.57	XPC	xeroderma pigmentosum, complementation group C	54100	0.12
chr20_8125317_8125709	0.57	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)	12211	0.27
chr2_65258054_65258356	0.56	AC007386.4		6426	0.18
chr1_202132763_202133787	0.56	PTPN7	protein tyrosine phosphatase, non-receptor type 7	2559	0.21
chr12_1755993_1756558	0.56	ENSG00000266043	.	13271	0.18
chr6_91060753_91061282	0.56	ENSG00000266760	.	38556	0.18
chr1_1207528_1208557	0.56	UBE2J2	ubiquitin-conjugating enzyme E2, J2	809	0.37
chr5_119633464_119633615	0.56	ENSG00000251975	.	39809	0.22
chr3_196378797_196379044	0.56	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	12274	0.13
chr1_90013452_90013603	0.56	LRRC8B	leucine rich repeat containing 8 family, member B	20273	0.21
chr13_114831463_114832357	0.56	RASA3	RAS p21 protein activator 3	11528	0.24
chr2_176417653_176417879	0.56	ENSG00000221347	.	222665	0.02
chr3_46033619_46034065	0.56	FYCO1	FYVE and coiled-coil domain containing 1	3465	0.23
chr2_68631463_68631827	0.56	AC015969.3		38929	0.13
chr8_144286298_144286449	0.56	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	8695	0.14
chr3_43237083_43237612	0.56	ENSG00000222331	.	15016	0.22
chr9_123607989_123608514	0.55	PSMD5-AS1	PSMD5 antisense RNA 1 (head to head)	324	0.87
chr17_2298935_2299087	0.55	MNT	MAX network transcriptional repressor	5387	0.12
chr1_56962140_56962350	0.55	PPAP2B	phosphatidic acid phosphatase type 2B	82996	0.1
chr16_16119784_16120030	0.55	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	16194	0.23
chr1_112015953_112016200	0.55	C1orf162	chromosome 1 open reading frame 162	338	0.78
chr5_126187384_126187849	0.55	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	66304	0.11
chr14_65556858_65557152	0.55	RP11-840I19.3		290	0.88
chr6_161647774_161647954	0.55	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	47187	0.2
chr20_24935566_24936123	0.55	CST7	cystatin F (leukocystatin)	5978	0.21
chr1_155209419_155209779	0.55	GBA	glucosidase, beta, acid	1418	0.16
chr2_143902895_143903369	0.55	ARHGAP15	Rho GTPase activating protein 15	16249	0.23
chr1_54686195_54686878	0.55	MRPL37	mitochondrial ribosomal protein L37	10917	0.13
chr2_99105742_99105999	0.55	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	30642	0.19
chr3_120162985_120163136	0.55	FSTL1	follistatin-like 1	6778	0.27
chr3_20165349_20165500	0.55	ENSG00000266745	.	13633	0.19
chr7_114616275_114616426	0.55	MDFIC	MyoD family inhibitor domain containing	42426	0.21
chr17_1100600_1101315	0.55	ABR	active BCR-related	10341	0.19
chr3_150996404_150996654	0.54	P2RY14	purinergic receptor P2Y, G-protein coupled, 14	274	0.9
chr14_24837858_24838637	0.54	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	41	0.94
chr14_93053486_93054197	0.54	RIN3	Ras and Rab interactor 3	65005	0.13
chr4_37894193_37894870	0.54	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	1811	0.44
chr3_18445696_18446011	0.54	RP11-158G18.1		5274	0.25
chr11_6676346_6676579	0.54	DCHS1	dachsous cadherin-related 1	623	0.54
chr5_98268754_98268997	0.54	ENSG00000200351	.	3576	0.26
chr8_125207320_125207810	0.54	FER1L6-AS2	FER1L6 antisense RNA 2	23802	0.22
chr4_108951026_108951527	0.54	HADH	hydroxyacyl-CoA dehydrogenase	25485	0.19
chr1_112045793_112046152	0.54	ADORA3	adenosine A3 receptor	138	0.93
chr3_31506056_31506507	0.54	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	68001	0.12
chr9_127026264_127026636	0.54	RP11-121A14.3		1295	0.38
chr2_38861741_38862387	0.54	GALM	galactose mutarotase (aldose 1-epimerase)	30988	0.13
chr5_10537277_10538000	0.54	ANKRD33B	ankyrin repeat domain 33B	26942	0.15
chr8_121746886_121747646	0.54	RP11-713M15.1		26227	0.22
chr11_132555018_132555242	0.53	ENSG00000252703	.	159427	0.04
chr10_134391633_134392261	0.53	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	29483	0.19
chr10_30783280_30783465	0.53	MAP3K8	mitogen-activated protein kinase kinase kinase 8	55621	0.12
chr17_74140903_74141711	0.53	RNF157-AS1	RNF157 antisense RNA 1	3710	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.7	2.9	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.6	0.6	GO:0002326	B cell lineage commitment(GO:0002326)
0.6	2.5	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.6	1.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.5	2.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.5	1.5	GO:0010040	response to iron(II) ion(GO:0010040)
0.5	1.5	GO:0030210	heparin biosynthetic process(GO:0030210)
0.5	0.9	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.4	1.7	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4	1.2	GO:0060242	contact inhibition(GO:0060242)
0.4	1.5	GO:0015705	iodide transport(GO:0015705)
0.4	0.7	GO:0030223	neutrophil differentiation(GO:0030223)
0.4	0.7	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4	1.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.4	1.4	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.3	0.7	GO:0052257	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.3	1.0	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.3	1.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3	1.0	GO:0007343	egg activation(GO:0007343)
0.3	1.0	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.3	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.3	1.8	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.3	0.9	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	2.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.3	0.9	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3	7.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.3	0.9	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.3	0.5	GO:0033622	integrin activation(GO:0033622)
0.3	1.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.3	0.8	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.3	1.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.3	1.3	GO:0070670	response to interleukin-4(GO:0070670)
0.2	0.7	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	0.7	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.2	0.7	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2	0.9	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	1.6	GO:0002063	chondrocyte development(GO:0002063)
0.2	0.5	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.2	0.2	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.2	2.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.2	0.2	GO:0048541	Peyer's patch development(GO:0048541)
0.2	0.2	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2	0.9	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2	0.4	GO:0042510	regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510)
0.2	0.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	0.8	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.2	0.8	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.2	0.2	GO:0032613	interleukin-10 production(GO:0032613)
0.2	0.2	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.2	1.6	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.2	0.6	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.8	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2	0.8	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	0.8	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.2	0.4	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.9	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.2	0.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.2	1.5	GO:0043368	positive T cell selection(GO:0043368)
0.2	0.6	GO:0032506	cytokinetic process(GO:0032506)
0.2	0.2	GO:0071481	cellular response to X-ray(GO:0071481)
0.2	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	1.3	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2	0.4	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.9	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.2	1.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.2	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.2	0.9	GO:0002858	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2	0.5	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.2	GO:0002448	mast cell mediated immunity(GO:0002448)
0.2	0.5	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.2	0.3	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.2	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.2	0.5	GO:0014055	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.2	0.3	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2	0.3	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.2	2.0	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.2	0.8	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.2	0.6	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	0.6	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) negative regulation of glial cell proliferation(GO:0060253)
0.2	2.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	0.5	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.2	0.5	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.2	1.5	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	0.7	GO:0005513	detection of calcium ion(GO:0005513)
0.1	1.2	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.6	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.1	0.1	GO:0045079	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.4	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.1	0.4	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.6	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	1.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.8	GO:0050901	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.1	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.5	GO:0050798	activated T cell proliferation(GO:0050798)
0.1	0.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.4	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.5	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.6	GO:0042119	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1	0.5	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.5	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.2	GO:0019042	viral latency(GO:0019042)
0.1	0.4	GO:0051451	myoblast migration(GO:0051451)
0.1	1.5	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.7	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1	0.2	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1	0.3	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.9	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.6	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.9	GO:0040023	establishment of nucleus localization(GO:0040023)
0.1	0.4	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.7	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.1	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.1	0.1	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1	2.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.5	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.6	GO:0016556	mRNA modification(GO:0016556)
0.1	0.3	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1	0.1	GO:0001821	histamine secretion(GO:0001821)
0.1	0.4	GO:0060437	lung growth(GO:0060437)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.8	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.5	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.7	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.5	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.2	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.2	GO:0071503	response to heparin(GO:0071503)
0.1	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.1	GO:0032011	ARF protein signal transduction(GO:0032011)
0.1	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.1	GO:0032645	granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.1	0.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.4	GO:0070265	necrotic cell death(GO:0070265)
0.1	0.3	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.4	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.1	0.2	GO:0016553	base conversion or substitution editing(GO:0016553)
0.1	0.5	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.1	0.3	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.5	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1	0.3	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.4	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.2	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1	1.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.3	GO:0030204	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) chondroitin sulfate metabolic process(GO:0030204)
0.1	0.4	GO:0034505	tooth mineralization(GO:0034505)
0.1	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.3	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.3	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.5	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.1	0.2	GO:0014002	astrocyte development(GO:0014002)
0.1	1.4	GO:0050832	defense response to fungus(GO:0050832)
0.1	0.4	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.3	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1	0.2	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.1	0.4	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.1	0.2	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.1	0.3	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	0.3	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1	0.5	GO:0006857	oligopeptide transport(GO:0006857)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.2	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.1	0.1	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.4	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	0.2	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1	0.3	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.2	GO:0002507	tolerance induction(GO:0002507)
0.1	0.4	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	2.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.1	0.1	GO:0030202	heparin metabolic process(GO:0030202)
0.1	0.4	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.2	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.3	GO:0042117	monocyte activation(GO:0042117)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	1.1	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.5	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.1	0.4	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	2.1	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1	0.1	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.4	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.1	0.9	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.1	0.2	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.1	0.1	GO:0061054	dermatome development(GO:0061054)
0.1	0.1	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.1	0.2	GO:0009301	snRNA transcription(GO:0009301)
0.1	0.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.2	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.2	GO:0002068	glandular epithelial cell development(GO:0002068)
0.1	0.1	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	2.0	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.1	0.1	GO:0001878	response to yeast(GO:0001878)
0.1	0.3	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1	0.5	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.3	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	1.1	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.1	0.4	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1	0.5	GO:0042438	melanin biosynthetic process(GO:0042438)
0.1	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.1	0.3	GO:0015886	heme transport(GO:0015886)
0.1	0.1	GO:0002823	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.4	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.1	GO:0048342	paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.1	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.1	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.1	0.3	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.2	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.1	GO:0032647	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.1	0.2	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	0.2	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.1	0.3	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.1	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1	0.2	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	0.2	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.7	GO:0014823	response to activity(GO:0014823)
0.1	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	1.0	GO:0006611	protein export from nucleus(GO:0006611)
0.1	0.7	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	0.1	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.4	GO:0021854	hypothalamus development(GO:0021854)
0.1	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.1	GO:0032210	regulation of telomere maintenance via telomerase(GO:0032210)
0.1	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.2	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.1	0.2	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.1	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.4	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.1	0.2	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.1	0.3	GO:0030277	epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.2	GO:0005997	xylulose metabolic process(GO:0005997)
0.1	0.3	GO:0021561	facial nerve development(GO:0021561)
0.1	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	0.1	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.1	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.1	0.3	GO:0006020	inositol metabolic process(GO:0006020)
0.1	1.0	GO:0021766	hippocampus development(GO:0021766)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0046640	regulation of alpha-beta T cell proliferation(GO:0046640)
0.0	0.2	GO:0000239	pachytene(GO:0000239)
0.0	0.0	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0014010	glial cell proliferation(GO:0014009) Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.2	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.3	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0002715	regulation of natural killer cell mediated immunity(GO:0002715) regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0	2.5	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.0	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.3	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.1	GO:0070849	response to epidermal growth factor(GO:0070849)
0.0	0.2	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.3	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0034370	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0046666	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.2	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0042228	interleukin-8 biosynthetic process(GO:0042228)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.6	GO:0016998	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.0	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0	0.2	GO:0032528	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.5	GO:0098781	rRNA transcription(GO:0009303) ncRNA transcription(GO:0098781)
0.0	0.1	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0042441	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.0	GO:0045979	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.6	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.3	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.2	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.3	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0002676	regulation of chronic inflammatory response(GO:0002676)
0.0	0.3	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.0	GO:0032715	negative regulation of interleukin-6 production(GO:0032715)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.3	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.2	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.3	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.2	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	1.3	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.4	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.4	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.0	GO:0046398	UDP-glucuronate metabolic process(GO:0046398)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.0	GO:0002768	immune response-regulating cell surface receptor signaling pathway(GO:0002768)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0051875	pigment granule localization(GO:0051875)
0.0	0.1	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.5	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.2	GO:0050935	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.5	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.0	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.0	GO:0042435	serotonin metabolic process(GO:0042428) indole-containing compound biosynthetic process(GO:0042435) primary amino compound metabolic process(GO:1901160)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.5	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:1904478	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.0	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0019374	galactolipid metabolic process(GO:0019374)
0.0	0.0	GO:0039703	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.0	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.0	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.2	GO:0006903	vesicle targeting(GO:0006903)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	0.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	0.5	GO:0033270	paranode region of axon(GO:0033270)
0.2	0.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	0.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	1.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.2	0.6	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	2.4	GO:0001772	immunological synapse(GO:0001772)
0.2	0.6	GO:0033268	node of Ranvier(GO:0033268)
0.2	2.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	1.1	GO:0001891	phagocytic cup(GO:0001891)
0.2	0.5	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0032009	early phagosome(GO:0032009)
0.1	0.6	GO:0043218	compact myelin(GO:0043218)
0.1	1.3	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.8	GO:0045179	apical cortex(GO:0045179)
0.1	0.5	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.4	GO:0042629	mast cell granule(GO:0042629)
0.1	0.5	GO:0033011	perinuclear theca(GO:0033011)
0.1	0.7	GO:0030673	axolemma(GO:0030673)
0.1	0.3	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.3	GO:0071942	XPC complex(GO:0071942)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.4	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.5	GO:0042382	paraspeckles(GO:0042382)
0.1	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.6	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.7	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.9	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1	0.5	GO:0032590	dendrite membrane(GO:0032590)
0.1	1.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.5	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	2.4	GO:0030175	filopodium(GO:0030175)
0.1	0.5	GO:0000346	transcription export complex(GO:0000346)
0.1	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.3	GO:0030904	retromer complex(GO:0030904)
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.2	GO:0030313	cell envelope(GO:0030313)
0.1	0.6	GO:0071203	WASH complex(GO:0071203)
0.1	1.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.3	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.7	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.5	GO:0031941	filamentous actin(GO:0031941)
0.1	0.2	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	6.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0044462	external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0	0.4	GO:0032838	cell projection cytoplasm(GO:0032838)
0.0	0.2	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0070938	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.2	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.4	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	1.6	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	1.4	GO:0016605	PML body(GO:0016605)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.3	GO:0016460	myosin II complex(GO:0016460)
0.0	0.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	1.3	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0046658	anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.6	1.7	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5	1.5	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.4	2.7	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.4	1.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.4	1.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4	1.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.3	1.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3	1.9	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.3	0.9	GO:0042608	T cell receptor binding(GO:0042608)
0.3	1.1	GO:0070097	delta-catenin binding(GO:0070097)
0.3	1.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3	1.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.3	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.3	5.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	2.1	GO:0005522	profilin binding(GO:0005522)
0.3	1.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.3	2.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.2	0.7	GO:0033691	sialic acid binding(GO:0033691)
0.2	0.7	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	0.7	GO:0031628	opioid receptor binding(GO:0031628)
0.2	0.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	0.7	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	1.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.2	1.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2	0.9	GO:0015925	galactosidase activity(GO:0015925)
0.2	0.6	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.2	1.9	GO:0019864	IgG binding(GO:0019864)
0.2	0.8	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	0.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	0.6	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.2	0.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2	0.8	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.2	0.7	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	1.4	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.2	0.9	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	0.8	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.2	1.9	GO:0004697	protein kinase C activity(GO:0004697)
0.2	0.5	GO:0035197	siRNA binding(GO:0035197)
0.2	0.8	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.4	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	1.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.6	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.1	1.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	2.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	6.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	1.0	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.7	GO:0030274	LIM domain binding(GO:0030274)
0.1	4.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.5	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1	0.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	1.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.3	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.4	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	1.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	2.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	2.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.1	0.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.3	GO:0004802	transketolase activity(GO:0004802)
0.1	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.8	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	1.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.2	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.7	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.3	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.5	GO:0048156	tau protein binding(GO:0048156)
0.1	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.3	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.3	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	1.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.7	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.3	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.5	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.6	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.3	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	2.7	GO:0017048	Rho GTPase binding(GO:0017048)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.1	GO:0060229	lipase activator activity(GO:0060229)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	1.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.2	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.3	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1	0.5	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	0.5	GO:0070513	death domain binding(GO:0070513)
0.1	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.3	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.5	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.1	0.3	GO:0046790	virion binding(GO:0046790)
0.1	0.6	GO:0042166	acetylcholine binding(GO:0042166)
0.1	3.7	GO:0008301	DNA binding, bending(GO:0008301)
0.1	0.3	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	1.0	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.3	GO:0000977	transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	1.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.1	0.3	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0031177	phosphopantetheine binding(GO:0031177)
0.1	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	0.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.2	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.5	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.4	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.2	GO:0002054	nucleobase binding(GO:0002054)
0.1	0.6	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.3	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.8	GO:0010181	FMN binding(GO:0010181)
0.1	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	4.1	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.3	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.2	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.1	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	1.1	GO:0017022	myosin binding(GO:0017022)
0.1	0.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.0	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.2	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	1.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.2	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.6	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.2	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.4	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.2	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.9	GO:0070330	aromatase activity(GO:0070330)
0.0	0.3	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.3	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.0	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.5	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.6	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.1	GO:0016160	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.3	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.5	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.0	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.0	GO:0005217	intracellular ligand-gated ion channel activity(GO:0005217)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.7	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0004953	icosanoid receptor activity(GO:0004953)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	4.0	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	1.5	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.5	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0031779	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	3.8	GO:0004984	olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	4.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	3.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	9.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	10.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	5.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	0.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.2	1.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	1.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	4.2	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	0.9	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	2.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.5	PID ARF6 PATHWAY	Arf6 signaling events
0.1	0.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.7	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	0.6	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	1.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	1.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	1.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.3	PID EPO PATHWAY	EPO signaling pathway
0.1	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.6	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.6	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.8	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	1.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	1.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.4	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.3	PID RHOA REG PATHWAY	Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.5	5.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.4	4.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	3.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	4.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	1.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	3.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.2	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	4.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	2.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	3.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2	3.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	1.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	3.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	0.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	1.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	2.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	0.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	1.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	4.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	4.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	1.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	1.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.8	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.8	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	2.1	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	2.6	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.8	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Results for MEIS2

Z-value: 1.62

Motif logo

Transcription factors associated with MEIS2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MEIS2 motif across conditions

Conditions sorted by the z-value of the MEIS2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: