Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MEIS2

Z-value: 1.62

Motif logo

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Transcription factors associated with MEIS2

Gene Symbol Gene ID Gene Info
ENSG00000134138.15 MEIS2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MEIS2chr15_37387462_373877633900.871649-0.872.0e-03Click!
MEIS2chr15_37402971_3740312295420.226269-0.854.0e-03Click!
MEIS2chr15_37402742_3740289393130.226705-0.844.4e-03Click!
MEIS2chr15_37394546_3739476411510.518203-0.771.6e-02Click!
MEIS2chr15_37390143_373903142750.883031-0.722.8e-02Click!

Activity of the MEIS2 motif across conditions

Conditions sorted by the z-value of the MEIS2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrY_117140_117541 2.20 NA
NA
> 106
NA
chr17_78845626_78846398 1.86 RPTOR
regulatory associated protein of MTOR, complex 1
50512
0.1
chr17_76875045_76875748 1.31 TIMP2
TIMP metallopeptidase inhibitor 2
5164
0.16
chr12_121678757_121679425 1.29 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
19254
0.17
chr10_76672520_76672974 1.09 KAT6B
K(lysine) acetyltransferase 6B
74289
0.1
chr20_8380540_8381084 0.99 PLCB1-IT1
PLCB1 intronic transcript 1 (non-protein coding)
151440
0.04
chr11_68319868_68320209 0.91 PPP6R3
protein phosphatase 6, regulatory subunit 3
6072
0.21
chr10_114139672_114139929 0.91 ACSL5
acyl-CoA synthetase long-chain family member 5
3843
0.23
chrX_167199_167448 0.90 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
25666
0.23
chr22_40642780_40643209 0.90 TNRC6B
trinucleotide repeat containing 6B
18013
0.23
chr8_22499257_22499720 0.89 BIN3
bridging integrator 3
2829
0.16
chr6_159125474_159126340 0.88 SYTL3
synaptotagmin-like 3
41712
0.13
chr16_29129607_29129944 0.86 CTB-134H23.3

11009
0.16
chr8_125575470_125576116 0.85 MTSS1
metastasis suppressor 1
2175
0.26
chr6_170404847_170405519 0.84 RP11-302L19.1

72558
0.11
chr15_50392799_50393114 0.84 ATP8B4
ATPase, class I, type 8B, member 4
13745
0.23
chr3_196368477_196368981 0.83 PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
2083
0.21
chr8_21766211_21767399 0.83 DOK2
docking protein 2, 56kDa
4369
0.22
chr10_51503867_51504211 0.83 AGAP7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
17712
0.18
chr18_2883602_2883982 0.81 EMILIN2
elastin microfibril interfacer 2
36764
0.11
chr17_72008045_72008710 0.81 RPL38
ribosomal protein L38
191344
0.02
chr3_16551168_16551938 0.80 RFTN1
raftlin, lipid raft linker 1
2858
0.36
chr11_587585_588264 0.80 PHRF1
PHD and ring finger domains 1
11403
0.07
chr12_68841133_68841474 0.80 MDM1
Mdm1 nuclear protein homolog (mouse)
115142
0.06
chr3_141218689_141219075 0.80 RASA2
RAS p21 protein activator 2
12991
0.21
chr12_65043801_65044168 0.80 RP11-338E21.3

4815
0.15
chr20_39510251_39510483 0.79 ENSG00000238908
.
27498
0.24
chr11_4006180_4006517 0.78 STIM1
stromal interaction molecule 1
37775
0.14
chr11_129988351_129988943 0.78 ST14
suppression of tumorigenicity 14 (colon carcinoma)
40810
0.15
chr2_241504090_241504573 0.78 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
890
0.44
chr9_37486177_37486967 0.78 POLR1E
polymerase (RNA) I polypeptide E, 53kDa
422
0.8
chr2_136814753_136815076 0.78 AC093391.2

44879
0.15
chr14_98689187_98689819 0.77 ENSG00000222066
.
108584
0.07
chrX_1689699_1690290 0.77 AKAP17A
A kinase (PRKA) anchor protein 17A
20492
0.18
chr17_19273582_19274475 0.77 MAPK7
mitogen-activated protein kinase 7
7006
0.11
chr5_169232621_169233022 0.77 CTB-37A13.1

26452
0.22
chr21_36800534_36801386 0.76 ENSG00000211590
.
292053
0.01
chr11_3918269_3918516 0.76 STIM1
stromal interaction molecule 1
6301
0.14
chr9_4596503_4596823 0.75 SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
24328
0.19
chr5_96232467_96233018 0.75 ERAP2
endoplasmic reticulum aminopeptidase 2
7821
0.17
chr14_91718270_91718619 0.73 GPR68
G protein-coupled receptor 68
1780
0.32
chr16_30470032_30470581 0.73 ENSG00000202476
.
4888
0.07
chr6_37891842_37892090 0.73 ZFAND3
zinc finger, AN1-type domain 3
5769
0.23
chr9_129285864_129286127 0.73 ENSG00000221768
.
7275
0.22
chr7_102069746_102070456 0.73 ORAI2
ORAI calcium release-activated calcium modulator 2
3452
0.11
chr18_60880832_60881273 0.72 ENSG00000238988
.
19154
0.21
chr9_112827201_112827453 0.72 AKAP2
A kinase (PRKA) anchor protein 2
16351
0.27
chr2_10521424_10521869 0.72 HPCAL1
hippocalcin-like 1
38501
0.14
chr11_68272006_68272464 0.71 ENSG00000222339
.
884
0.48
chr1_156477763_156478531 0.71 MEF2D
myocyte enhancer factor 2D
7527
0.12
chr8_22562900_22563666 0.70 EGR3
early growth response 3
12468
0.13
chr17_74265724_74266071 0.70 UBALD2
UBA-like domain containing 2
4113
0.15
chr2_70331989_70332203 0.69 PCBP1-AS1
PCBP1 antisense RNA 1
16118
0.15
chr11_1145070_1145742 0.69 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
6174
0.2
chr8_37132456_37132991 0.69 RP11-150O12.6

241816
0.02
chr14_100568508_100568904 0.69 EVL
Enah/Vasp-like
5422
0.14
chr7_139922545_139922896 0.68 ENSG00000199971
.
13249
0.16
chr17_57442435_57442935 0.68 ENSG00000263857
.
759
0.63
chr22_24830948_24831363 0.68 ADORA2A
adenosine A2a receptor
2347
0.28
chr3_66534161_66534516 0.68 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
17018
0.29
chr19_14486268_14486999 0.67 CD97
CD97 molecule
5335
0.16
chr6_10413127_10413925 0.66 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
414
0.77
chr2_242067669_242067932 0.66 PASK
PAS domain containing serine/threonine kinase
11210
0.14
chr10_12636480_12636937 0.66 ENSG00000263584
.
15956
0.26
chr6_3026729_3027148 0.66 RP1-90J20.11

1913
0.25
chr9_77765507_77765901 0.66 ENSG00000200041
.
30833
0.16
chr3_23935568_23935872 0.66 RPL15
ribosomal protein L15
22316
0.17
chr1_2174913_2175173 0.66 SKI
v-ski avian sarcoma viral oncogene homolog
14909
0.12
chr16_29611332_29612125 0.66 ENSG00000266758
.
1142
0.43
chr2_145266955_145267602 0.65 ZEB2
zinc finger E-box binding homeobox 2
7837
0.25
chr6_111880308_111880661 0.65 TRAF3IP2-AS1
TRAF3IP2 antisense RNA 1
5970
0.19
chr7_50354105_50354370 0.65 IKZF1
IKAROS family zinc finger 1 (Ikaros)
5919
0.31
chr2_3246663_3247121 0.65 TSSC1-IT1
TSSC1 intronic transcript 1 (non-protein coding)
58344
0.14
chr9_92151633_92152777 0.65 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
39160
0.16
chrX_128888588_128889150 0.64 XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
15871
0.19
chr4_4462962_4463617 0.64 STX18
syntaxin 18
392
0.87
chr3_197574613_197575155 0.64 LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
12
0.98
chr3_71103539_71103766 0.64 FOXP1
forkhead box P1
10425
0.31
chr4_122111518_122111869 0.64 ENSG00000252183
.
2365
0.34
chr10_104408471_104409659 0.64 TRIM8
tripartite motif containing 8
4421
0.2
chr11_48025895_48026348 0.64 AC103828.1

11286
0.2
chr17_73061461_73061965 0.64 KCTD2
potassium channel tetramerization domain containing 2
18373
0.07
chr5_169714509_169715053 0.63 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
10450
0.22
chr16_30483819_30483970 0.63 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
85
0.88
chr12_15803315_15803614 0.63 EPS8
epidermal growth factor receptor pathway substrate 8
11744
0.22
chr19_16483828_16484062 0.63 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
11181
0.14
chr19_16228666_16229162 0.63 RAB8A
RAB8A, member RAS oncogene family
6207
0.14
chr12_662501_663191 0.63 B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
10547
0.16
chr9_116278367_116278657 0.63 RGS3
regulator of G-protein signaling 3
1038
0.59
chr2_37847075_37847226 0.63 AC006369.2

19871
0.22
chr3_99792803_99793269 0.62 FILIP1L
filamin A interacting protein 1-like
40321
0.15
chr13_100072786_100073153 0.62 ENSG00000266207
.
32754
0.16
chr10_134235955_134236340 0.62 RP11-432J24.3

18841
0.16
chr16_57564544_57565110 0.62 CCDC102A
coiled-coil domain containing 102A
5684
0.15
chr18_60804974_60805454 0.62 RP11-299P2.1

13339
0.24
chr14_93122585_93123047 0.62 RIN3
Ras and Rab interactor 3
3970
0.31
chr13_99935557_99935841 0.62 GPR18
G protein-coupled receptor 18
21701
0.17
chr11_326229_326864 0.62 IFITM3
interferon induced transmembrane protein 3
991
0.28
chr17_36884755_36885077 0.62 AC006449.1
NS5ATP13TP1; Uncharacterized protein
465
0.53
chr6_2901195_2901808 0.62 SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
2013
0.31
chr21_36345967_36346246 0.62 RUNX1
runt-related transcription factor 1
75356
0.12
chr16_1609129_1609769 0.62 LA16c-425C2.1

20860
0.08
chr2_42106310_42106729 0.62 ENSG00000223245
.
8108
0.23
chr9_130789038_130789532 0.61 RP11-379C10.1

30356
0.08
chr22_30059316_30059467 0.61 RP1-76B20.12

56312
0.08
chr1_249116365_249116887 0.61 ENSG00000264500
.
3950
0.17
chrX_13068365_13068668 0.61 FAM9C
family with sequence similarity 9, member C
5715
0.29
chr10_33208774_33208970 0.61 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
11441
0.29
chr10_6390281_6390901 0.61 DKFZP667F0711

1687
0.47
chr10_76660118_76660645 0.61 KAT6B
K(lysine) acetyltransferase 6B
61923
0.13
chr10_14639310_14639675 0.61 FAM107B
family with sequence similarity 107, member B
6896
0.24
chr2_27297539_27298497 0.61 OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
3377
0.09
chr16_84551314_84551501 0.61 TLDC1
TBC/LysM-associated domain containing 1
13043
0.17
chr1_209932210_209932881 0.60 TRAF3IP3
TRAF3 interacting protein 3
702
0.6
chr1_168482288_168482558 0.60 XCL2
chemokine (C motif) ligand 2
30812
0.2
chr20_44712187_44712338 0.60 NCOA5
nuclear receptor coactivator 5
6329
0.17
chr13_99156494_99156904 0.60 STK24
serine/threonine kinase 24
14822
0.22
chr18_43268528_43268819 0.60 SLC14A2
solute carrier family 14 (urea transporter), member 2
22566
0.17
chr1_90117224_90117495 0.60 LRRC8C
leucine rich repeat containing 8 family, member C
18728
0.16
chrX_109941851_109942119 0.60 CHRDL1
chordin-like 1
97008
0.09
chr10_51499020_51499441 0.60 AGAP7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
12903
0.2
chr9_21558528_21559235 0.60 MIR31HG
MIR31 host gene (non-protein coding)
787
0.64
chr1_95223071_95223415 0.60 ENSG00000263526
.
11787
0.24
chr19_16555192_16555446 0.59 CTD-2013N17.4

3562
0.16
chr4_2299878_2300029 0.59 RP11-478C1.7

2642
0.2
chr19_18414911_18415207 0.59 LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
12010
0.09
chr4_25845411_25845804 0.59 SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
16646
0.24
chr7_44804340_44804491 0.59 ZMIZ2
zinc finger, MIZ-type containing 2
8611
0.16
chr8_128990046_128990302 0.59 ENSG00000221771
.
17295
0.16
chr11_36112461_36112922 0.59 ENSG00000263389
.
81043
0.09
chr16_68117516_68117708 0.59 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
1635
0.23
chr2_161329613_161329866 0.59 RBMS1
RNA binding motif, single stranded interacting protein 1
20290
0.24
chr17_57733680_57734015 0.59 CLTC
clathrin, heavy chain (Hc)
27420
0.15
chrX_13735290_13735441 0.59 TRAPPC2
trafficking protein particle complex 2
17310
0.16
chr1_226840930_226841348 0.59 ITPKB-IT1
ITPKB intronic transcript 1 (non-protein coding)
6232
0.23
chr14_102323762_102323913 0.58 CTD-2017C7.1

17969
0.16
chr16_17441111_17441650 0.58 XYLT1
xylosyltransferase I
123358
0.06
chr17_19993225_19993666 0.58 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
3110
0.28
chr20_32119885_32120303 0.58 CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
30046
0.15
chr15_40548529_40548680 0.58 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
3219
0.13
chr2_241560209_241560581 0.58 GPR35
G protein-coupled receptor 35
4267
0.16
chr19_16448880_16449487 0.58 KLF2
Kruppel-like factor 2
13532
0.14
chr8_116661022_116661259 0.58 TRPS1
trichorhinophalangeal syndrome I
12765
0.31
chr22_24841252_24841667 0.58 ADORA2A
adenosine A2a receptor
12651
0.16
chr6_166900667_166901285 0.58 ENSG00000222958
.
21945
0.16
chr6_154692239_154692666 0.58 IPCEF1
interaction protein for cytohesin exchange factors 1
14526
0.27
chr7_27004125_27004483 0.58 SKAP2
src kinase associated phosphoprotein 2
30554
0.16
chr10_6182182_6182929 0.57 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
4326
0.16
chr3_14274255_14274511 0.57 XPC
xeroderma pigmentosum, complementation group C
54100
0.12
chr20_8125317_8125709 0.57 PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
12211
0.27
chr2_65258054_65258356 0.56 AC007386.4

6426
0.18
chr1_202132763_202133787 0.56 PTPN7
protein tyrosine phosphatase, non-receptor type 7
2559
0.21
chr12_1755993_1756558 0.56 ENSG00000266043
.
13271
0.18
chr6_91060753_91061282 0.56 ENSG00000266760
.
38556
0.18
chr1_1207528_1208557 0.56 UBE2J2
ubiquitin-conjugating enzyme E2, J2
809
0.37
chr5_119633464_119633615 0.56 ENSG00000251975
.
39809
0.22
chr3_196378797_196379044 0.56 PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
12274
0.13
chr1_90013452_90013603 0.56 LRRC8B
leucine rich repeat containing 8 family, member B
20273
0.21
chr13_114831463_114832357 0.56 RASA3
RAS p21 protein activator 3
11528
0.24
chr2_176417653_176417879 0.56 ENSG00000221347
.
222665
0.02
chr3_46033619_46034065 0.56 FYCO1
FYVE and coiled-coil domain containing 1
3465
0.23
chr2_68631463_68631827 0.56 AC015969.3

38929
0.13
chr8_144286298_144286449 0.56 GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
8695
0.14
chr3_43237083_43237612 0.56 ENSG00000222331
.
15016
0.22
chr9_123607989_123608514 0.55 PSMD5-AS1
PSMD5 antisense RNA 1 (head to head)
324
0.87
chr17_2298935_2299087 0.55 MNT
MAX network transcriptional repressor
5387
0.12
chr1_56962140_56962350 0.55 PPAP2B
phosphatidic acid phosphatase type 2B
82996
0.1
chr16_16119784_16120030 0.55 ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
16194
0.23
chr1_112015953_112016200 0.55 C1orf162
chromosome 1 open reading frame 162
338
0.78
chr5_126187384_126187849 0.55 MARCH3
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
66304
0.11
chr14_65556858_65557152 0.55 RP11-840I19.3

290
0.88
chr6_161647774_161647954 0.55 AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
47187
0.2
chr20_24935566_24936123 0.55 CST7
cystatin F (leukocystatin)
5978
0.21
chr1_155209419_155209779 0.55 GBA
glucosidase, beta, acid
1418
0.16
chr2_143902895_143903369 0.55 ARHGAP15
Rho GTPase activating protein 15
16249
0.23
chr1_54686195_54686878 0.55 MRPL37
mitochondrial ribosomal protein L37
10917
0.13
chr2_99105742_99105999 0.55 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
30642
0.19
chr3_120162985_120163136 0.55 FSTL1
follistatin-like 1
6778
0.27
chr3_20165349_20165500 0.55 ENSG00000266745
.
13633
0.19
chr7_114616275_114616426 0.55 MDFIC
MyoD family inhibitor domain containing
42426
0.21
chr17_1100600_1101315 0.55 ABR
active BCR-related
10341
0.19
chr3_150996404_150996654 0.54 P2RY14
purinergic receptor P2Y, G-protein coupled, 14
274
0.9
chr14_24837858_24838637 0.54 NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
41
0.94
chr14_93053486_93054197 0.54 RIN3
Ras and Rab interactor 3
65005
0.13
chr4_37894193_37894870 0.54 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
1811
0.44
chr3_18445696_18446011 0.54 RP11-158G18.1

5274
0.25
chr11_6676346_6676579 0.54 DCHS1
dachsous cadherin-related 1
623
0.54
chr5_98268754_98268997 0.54 ENSG00000200351
.
3576
0.26
chr8_125207320_125207810 0.54 FER1L6-AS2
FER1L6 antisense RNA 2
23802
0.22
chr4_108951026_108951527 0.54 HADH
hydroxyacyl-CoA dehydrogenase
25485
0.19
chr1_112045793_112046152 0.54 ADORA3
adenosine A3 receptor
138
0.93
chr3_31506056_31506507 0.54 STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
68001
0.12
chr9_127026264_127026636 0.54 RP11-121A14.3

1295
0.38
chr2_38861741_38862387 0.54 GALM
galactose mutarotase (aldose 1-epimerase)
30988
0.13
chr5_10537277_10538000 0.54 ANKRD33B
ankyrin repeat domain 33B
26942
0.15
chr8_121746886_121747646 0.54 RP11-713M15.1

26227
0.22
chr11_132555018_132555242 0.53 ENSG00000252703
.
159427
0.04
chr10_134391633_134392261 0.53 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
29483
0.19
chr10_30783280_30783465 0.53 MAP3K8
mitogen-activated protein kinase kinase kinase 8
55621
0.12
chr17_74140903_74141711 0.53 RNF157-AS1
RNF157 antisense RNA 1
3710
0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MEIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.7 2.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.6 0.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.6 2.5 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.6 1.3 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.5 2.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.5 1.5 GO:0010040 response to iron(II) ion(GO:0010040)
0.5 1.5 GO:0030210 heparin biosynthetic process(GO:0030210)
0.5 0.9 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.4 1.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 1.2 GO:0060242 contact inhibition(GO:0060242)
0.4 1.5 GO:0015705 iodide transport(GO:0015705)
0.4 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.4 0.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 1.4 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.3 0.7 GO:0052257 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.3 1.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.3 1.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 1.0 GO:0007343 egg activation(GO:0007343)
0.3 1.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 1.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 0.9 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 0.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 7.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 0.9 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.3 0.5 GO:0033622 integrin activation(GO:0033622)
0.3 1.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 0.8 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.3 1.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.3 1.3 GO:0070670 response to interleukin-4(GO:0070670)
0.2 0.7 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.7 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.2 0.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 0.9 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.6 GO:0002063 chondrocyte development(GO:0002063)
0.2 0.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 0.2 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.2 2.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.2 0.2 GO:0048541 Peyer's patch development(GO:0048541)
0.2 0.2 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.9 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2 0.4 GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510)
0.2 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.2 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.2 GO:0032613 interleukin-10 production(GO:0032613)
0.2 0.2 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.2 1.6 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.2 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.8 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 0.8 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 0.8 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.9 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.2 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 1.5 GO:0043368 positive T cell selection(GO:0043368)
0.2 0.6 GO:0032506 cytokinetic process(GO:0032506)
0.2 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 1.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.2 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.9 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.2 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.9 GO:0002858 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.2 0.2 GO:0002448 mast cell mediated immunity(GO:0002448)
0.2 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.2 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.2 0.5 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.2 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2 0.3 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.2 2.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.2 0.8 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.6 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) negative regulation of glial cell proliferation(GO:0060253)
0.2 2.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.5 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.2 0.5 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.5 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.2 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 0.1 GO:0045079 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.6 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.1 0.1 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.5 GO:0050798 activated T cell proliferation(GO:0050798)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.4 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.5 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.5 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.2 GO:0019042 viral latency(GO:0019042)
0.1 0.4 GO:0051451 myoblast migration(GO:0051451)
0.1 1.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.9 GO:0040023 establishment of nucleus localization(GO:0040023)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.1 0.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1 2.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.6 GO:0016556 mRNA modification(GO:0016556)
0.1 0.3 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.1 GO:0001821 histamine secretion(GO:0001821)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.5 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.2 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.3 GO:0001714 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1 0.2 GO:0071503 response to heparin(GO:0071503)
0.1 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.1 GO:0032011 ARF protein signal transduction(GO:0032011)
0.1 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.1 GO:0032645 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0070265 necrotic cell death(GO:0070265)
0.1 0.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.4 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.1 0.2 GO:0016553 base conversion or substitution editing(GO:0016553)
0.1 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1 0.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.4 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.2 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.1 1.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.3 GO:0030204 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) chondroitin sulfate metabolic process(GO:0030204)
0.1 0.4 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.5 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.2 GO:0014002 astrocyte development(GO:0014002)
0.1 1.4 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.4 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.4 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.1 0.2 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.1 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.5 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 0.1 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.4 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0002507 tolerance induction(GO:0002507)
0.1 0.4 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 2.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.3 GO:0042117 monocyte activation(GO:0042117)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.1 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.5 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.1 0.2 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.1 2.1 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.1 0.1 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.1 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.1 GO:0061054 dermatome development(GO:0061054)
0.1 0.1 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.2 GO:0002068 glandular epithelial cell development(GO:0002068)
0.1 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 2.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.1 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 1.1 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.1 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.1 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.1 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.1 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.2 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.1 GO:0032647 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647)
0.1 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 0.3 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.1 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 0.2 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.1 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.7 GO:0014823 response to activity(GO:0014823)
0.1 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.0 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:0021854 hypothalamus development(GO:0021854)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.1 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.2 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1 0.4 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.2 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.1 0.3 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.3 GO:0021561 facial nerve development(GO:0021561)
0.1 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.1 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.1 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.0 GO:0021766 hippocampus development(GO:0021766)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0046640 regulation of alpha-beta T cell proliferation(GO:0046640)
0.0 0.2 GO:0000239 pachytene(GO:0000239)
0.0 0.0 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0014010 glial cell proliferation(GO:0014009) Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.3 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0002715 regulation of natural killer cell mediated immunity(GO:0002715) regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 2.5 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0031000 response to caffeine(GO:0031000)
0.0 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0070849 response to epidermal growth factor(GO:0070849)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0042228 interleukin-8 biosynthetic process(GO:0042228)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.2 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.5 GO:0098781 rRNA transcription(GO:0009303) ncRNA transcription(GO:0098781)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0045979 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.2 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0002676 regulation of chronic inflammatory response(GO:0002676)
0.0 0.3 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.0 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0016048 detection of temperature stimulus(GO:0016048) detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0019730 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.3 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.2 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:1901663 quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 1.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.0 GO:0042160 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.0 GO:0002768 immune response-regulating cell surface receptor signaling pathway(GO:0002768)
0.0 0.0 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0051875 pigment granule localization(GO:0051875)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0050935 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.5 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.0 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0 0.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.0 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.0 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0042435 serotonin metabolic process(GO:0042428) indole-containing compound biosynthetic process(GO:0042435) primary amino compound metabolic process(GO:1901160)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.0 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:1904478 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.0 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0070193 synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0019374 galactolipid metabolic process(GO:0019374)
0.0 0.0 GO:0039703 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.0 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.0 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:0006903 vesicle targeting(GO:0006903)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.2 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 2.4 GO:0001772 immunological synapse(GO:0001772)
0.2 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.2 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0032009 early phagosome(GO:0032009)
0.1 0.6 GO:0043218 compact myelin(GO:0043218)
0.1 1.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.5 GO:0033011 perinuclear theca(GO:0033011)
0.1 0.7 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.4 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0000346 transcription export complex(GO:0000346)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0030904 retromer complex(GO:0030904)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.2 GO:0030313 cell envelope(GO:0030313)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.2 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 6.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0044462 external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0 0.4 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0070938 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 1.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 1.3 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.6 1.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 1.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.4 2.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 1.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.4 1.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4 1.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.3 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.3 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 1.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 5.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 2.1 GO:0005522 profilin binding(GO:0005522)
0.3 1.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.3 2.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.2 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.9 GO:0015925 galactosidase activity(GO:0015925)
0.2 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.9 GO:0019864 IgG binding(GO:0019864)
0.2 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.6 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.2 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.8 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 0.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.2 0.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 0.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.2 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.2 0.5 GO:0035197 siRNA binding(GO:0035197)
0.2 0.8 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.1 1.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 6.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 4.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.3 GO:0004802 transketolase activity(GO:0004802)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0048156 tau protein binding(GO:0048156)
0.1 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.1 GO:0060229 lipase activator activity(GO:0060229)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.3 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 0.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.5 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.1 0.3 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.1 3.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0000977 transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.2 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.8 GO:0010181 FMN binding(GO:0010181)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 4.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.1 GO:0017022 myosin binding(GO:0017022)
0.1 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.0 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.2 GO:0080032 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.9 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.0 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.5 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.0 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.0 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.0 GO:0004953 icosanoid receptor activity(GO:0004953)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.5 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.5 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 3.8 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 4.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 3.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 9.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 10.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 5.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.2 1.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 1.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.5 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.3 PID EPO PATHWAY EPO signaling pathway
0.1 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 5.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 4.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 3.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 4.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 1.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 3.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 4.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 1.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.2 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 4.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.1 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 4.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.8 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 2.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.0 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines