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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MEIS3_TGIF2LX

Z-value: 1.06

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Transcription factors associated with MEIS3_TGIF2LX

Gene Symbol Gene ID Gene Info
MEIS3
ENSG00000105419.13 Meis homeobox 3
TGIF2LX
ENSG00000153779.8 TGFB induced factor homeobox 2 like X-linked

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_47930779_47930930MEIS380740.156354-0.551.2e-01Click!
chr19_47902354_47902505MEIS399800.1575570.551.3e-01Click!
chr19_47936281_47936432MEIS3135760.1418250.541.3e-01Click!
chr19_47893667_47893818MEIS3186670.1398280.511.6e-01Click!
chr19_47932297_47932448MEIS395920.151645-0.511.6e-01Click!

Activity of the MEIS3_TGIF2LX motif across conditions

Conditions sorted by the z-value of the MEIS3_TGIF2LX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_31364396_31364620 0.40 ITGAX
 integrin, alpha X (complement component 3 receptor 4 subunit)
 1947
 0.22
chr1_37195687_37195944 0.40 RP4-614N24.1
42926
 0.19
chr5_59090911_59091107 0.38 PDE4D
 phosphodiesterase 4D, cAMP-specific
 26538
 0.25
chr2_57825828_57826109 0.36 ENSG00000212168
 .
 54298
 0.18
chr2_65132087_65132267 0.36 ENSG00000244534
 .
 2095
 0.28
chr15_94406442_94406593 0.35 ENSG00000222409
 .
 33739
 0.25
chr3_53206532_53206683 0.34 PRKCD
 protein kinase C, delta
 7462
 0.18
chr3_34304883_34305090 0.33 PDCD6IP
 programmed cell death 6 interacting protein
 464871
 0.01
chrX_123521860_123522011 0.32 SH2D1A
 SH2 domain containing 1A
 41496
 0.21
chr1_87771024_87771216 0.32 LMO4
 LIM domain only 4
 23031
 0.26
chr16_12449826_12449977 0.32 SNX29
 sorting nexin 29
 209
 0.94
chr9_81309923_81310074 0.32 PSAT1
 phosphoserine aminotransferase 1
 397939
 0.01
chr22_47080714_47080865 0.32 GRAMD4
 GRAM domain containing 4
 10284
 0.22
chr1_48711061_48711404 0.31 RP5-1024N4.4
15999
 0.21
chr16_89044159_89044400 0.31 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
 667
 0.66
chr9_95876458_95876701 0.31 C9orf89
 chromosome 9 open reading frame 89
 18079
 0.14
chr1_40529943_40530230 0.31 PPT1
 palmitoyl-protein thioesterase 1
 17907
 0.17
chr18_77269712_77269863 0.31 AC018445.1
 Uncharacterized protein
 6270
 0.3
chr14_65519660_65519811 0.30 ENSG00000266531
 .
 8329
 0.14
chr7_76139277_76139433 0.30 UPK3B
 uroplakin 3B
 390
 0.81
chr22_47017621_47018011 0.29 GRAMD4
 GRAM domain containing 4
 1517
 0.48
chr15_68077042_68077264 0.29 SKOR1
 SKI family transcriptional corepressor 1
 34889
 0.2
chr1_43765747_43766019 0.29 TIE1
 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
 781
 0.52
chr16_11593490_11593706 0.28 CTD-3088G3.8
 Protein LOC388210
 7987
 0.15
chr6_34243280_34243535 0.28 C6orf1
 chromosome 6 open reading frame 1
 26160
 0.18
chr2_16844763_16844970 0.28 FAM49A
 family with sequence similarity 49, member A
 2230
 0.47
chr11_2697989_2698156 0.28 KCNQ1OT1
 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
 23152
 0.22
chr7_37429580_37430060 0.27 ENSG00000200113
 .
 29411
 0.16
chr6_24951319_24951727 0.27 FAM65B
 family with sequence similarity 65, member B
 15335
 0.22
chr5_34865017_34865168 0.26 CTD-2517O10.6
25709
 0.15
chr3_194696258_194696409 0.26 XXYLT1-AS1
 XXYLT1 antisense RNA 1
 118984
 0.05
chr12_7060138_7060323 0.26 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
 195
 0.81
chr11_76047608_76047759 0.26 PRKRIR
 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
 44303
 0.11
chr15_42676695_42676925 0.25 CAPN3
 calpain 3, (p94)
 17778
 0.15
chr11_105090744_105090960 0.25 CARD18
 caspase recruitment domain family, member 18
 80399
 0.1
chr10_131129546_131129832 0.25 MGMT
 O-6-methylguanine-DNA methyltransferase
 135759
 0.05
chr17_56692314_56692465 0.25 ENSG00000212195
 .
 16808
 0.12
chr22_17582429_17582621 0.25 IL17RA
 interleukin 17 receptor A
 16676
 0.14
chr6_47203496_47203647 0.25 TNFRSF21
 tumor necrosis factor receptor superfamily, member 21
 74070
 0.12
chr4_16032933_16033084 0.24 ENSG00000251758
 .
 22598
 0.19
chr16_81529220_81529493 0.24 CMIP
 c-Maf inducing protein
 402
 0.91
chr18_43904157_43904332 0.24 RNF165
 ring finger protein 165
 2528
 0.4
chr1_19235703_19235961 0.24 IFFO2
 intermediate filament family orphan 2
 2654
 0.22
chr9_21047360_21047561 0.24 PTPLAD2
 protein tyrosine phosphatase-like A domain containing 2
 15825
 0.18
chr9_84798219_84798630 0.24 SPATA31D1
 SPATA31 subfamily D, member 1
 194737
 0.03
chr5_78088517_78088668 0.24 LHFPL2
 lipoma HMGIC fusion partner-like 2
 143944
 0.05
chr1_206246898_206247049 0.24 ENSG00000252692
 .
 14120
 0.15
chr7_29308125_29308409 0.24 AC004593.3
59681
 0.12
chr12_11939644_11939800 0.24 ETV6
 ets variant 6
 34287
 0.22
chr8_25095577_25095889 0.23 DOCK5
 dedicator of cytokinesis 5
 53353
 0.15
chr11_60939371_60939609 0.23 VPS37C
 vacuolar protein sorting 37 homolog C (S. cerevisiae)
 10401
 0.15
chr21_45595773_45596048 0.23 AP001055.1
2330
 0.22
chr8_92363748_92363899 0.23 SLC26A7
 solute carrier family 26 (anion exchanger), member 7
 55971
 0.15
chr1_175809524_175809675 0.23 TNR
 tenascin R
 96693
 0.08
chr19_50018940_50019106 0.23 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
 1708
 0.13
chr1_230413095_230413246 0.23 RP5-956O18.3
4469
 0.26
chr18_21695534_21696122 0.23 TTC39C
 tetratricopeptide repeat domain 39C
 1591
 0.26
chr15_31115309_31115461 0.23 ENSG00000221379
 .
 21876
 0.16
chr6_12943954_12944105 0.23 PHACTR1
 phosphatase and actin regulator 1
 14185
 0.3
chr5_157661766_157661969 0.23 ENSG00000222626
 .
 257903
 0.02
chr13_101325397_101325635 0.23 TMTC4
 transmembrane and tetratricopeptide repeat containing 4
 1512
 0.47
chr2_26232079_26232230 0.23 AC013449.1
 Uncharacterized protein
 19327
 0.15
chr1_19686120_19686271 0.22 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 26096
 0.11
chr15_28413886_28414277 0.22 HERC2
 HECT and RLD domain containing E3 ubiquitin protein ligase 2
 5488
 0.29
chr4_15190631_15190980 0.22 RP11-665G4.1
38779
 0.19
chr12_124228990_124229141 0.22 ATP6V0A2
 ATPase, H+ transporting, lysosomal V0 subunit a2
 5478
 0.19
chr17_27889238_27889394 0.22 RP11-68I3.2
1751
 0.18
chr9_111885537_111885688 0.22 TMEM245
 transmembrane protein 245
 3387
 0.25
chr21_34439493_34439682 0.22 OLIG1
 oligodendrocyte transcription factor 1
 2863
 0.23
chr10_134235955_134236340 0.22 RP11-432J24.3
18841
 0.16
chr12_27155870_27156021 0.22 TM7SF3
 transmembrane 7 superfamily member 3
 273
 0.89
chr2_60627914_60628065 0.22 ENSG00000266078
 .
 13409
 0.22
chr11_70267723_70267874 0.21 CTTN
 cortactin
 1198
 0.41
chr15_57887157_57887308 0.21 GCOM1
 GRINL1A complex locus 1
 3001
 0.22
chr7_115625227_115625506 0.21 TFEC
 transcription factor EC
 17062
 0.28
chr17_48841397_48841548 0.21 LUC7L3
 LUC7-like 3 (S. cerevisiae)
 17492
 0.14
chr19_47233988_47234360 0.21 CTB-174O21.2
2314
 0.14
chr22_18253018_18253331 0.21 BID
 BH3 interacting domain death agonist
 3608
 0.22
chr19_31765985_31766213 0.21 AC007796.1
73688
 0.11
chr7_93869278_93869476 0.21 COL1A2
 collagen, type I, alpha 2
 154496
 0.04
chr1_229137271_229137454 0.21 RP5-1061H20.5
225947
 0.02
chr1_9422560_9422755 0.21 SPSB1
 splA/ryanodine receptor domain and SOCS box containing 1
 6891
 0.25
chr4_40561931_40562177 0.21 RBM47
 RNA binding motif protein 47
 44064
 0.15
chr9_111597664_111597815 0.21 ACTL7B
 actin-like 7B
 21500
 0.19
chr2_225269583_225269734 0.21 FAM124B
 family with sequence similarity 124B
 2856
 0.39
chr1_245424145_245424296 0.20 RP11-62I21.1
26417
 0.22
chr19_44297367_44297518 0.20 LYPD5
 LY6/PLAUR domain containing 5
 6739
 0.13
chr21_45631442_45631593 0.20 AP001057.1
10344
 0.12
chrX_148713668_148713871 0.20 TMEM185A
 transmembrane protein 185A
 201
 0.94
chr2_64489091_64489290 0.20 AC074289.1
33588
 0.2
chr22_26564894_26565205 0.20 SEZ6L
 seizure related 6 homolog (mouse)-like
 391
 0.87
chr12_10186853_10187023 0.20 CLEC9A
 C-type lectin domain family 9, member A
 3662
 0.14
chr12_2639416_2639567 0.20 CACNA1C-AS3
 CACNA1C antisense RNA 3
 77115
 0.1
chr6_111897306_111897457 0.20 TRAF3IP2-AS1
 TRAF3IP2 antisense RNA 1
 1559
 0.37
chr4_86622619_86622800 0.20 ENSG00000266421
 .
 20912
 0.26
chr10_94549884_94550135 0.20 EXOC6
 exocyst complex component 6
 40926
 0.17
chr21_39867625_39867922 0.20 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 2572
 0.43
chr6_20427872_20428026 0.20 ENSG00000252949
 .
 5400
 0.15
chr1_234885846_234885997 0.20 ENSG00000201638
 .
 87799
 0.08
chr10_23389093_23389313 0.20 MSRB2
 methionine sulfoxide reductase B2
 4768
 0.23
chr2_169482878_169483157 0.20 ENSG00000199348
 .
 20011
 0.22
chr2_171218393_171218731 0.20 AC012594.1
10934
 0.3
chr12_117463237_117463436 0.20 TESC
 tescalcin
 21300
 0.21
chr6_42343133_42343301 0.19 ENSG00000221252
 .
 36917
 0.17
chr2_233956975_233957215 0.19 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 31906
 0.16
chr19_52124679_52125032 0.19 SIGLEC5
 sialic acid binding Ig-like lectin 5
 8733
 0.11
chr3_4383206_4383357 0.19 SETMAR
 SET domain and mariner transposase fusion gene
 37989
 0.21
chr2_157327257_157327445 0.19 GPD2
 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
 2733
 0.29
chr5_142596063_142596214 0.19 ARHGAP26
 Rho GTPase activating protein 26
 9373
 0.25
chr1_16827341_16827546 0.19 CROCCP3
 ciliary rootlet coiled-coil, rootletin pseudogene 3
 9641
 0.13
chr12_111587807_111587958 0.19 CUX2
 cut-like homeobox 2
 50632
 0.15
chr19_18090395_18090751 0.19 ENSG00000252591
 .
 7739
 0.14
chr11_3188344_3188495 0.19 OSBPL5
 oxysterol binding protein-like 5
 1419
 0.35
chr10_81698298_81698654 0.19 SFTPD
 surfactant protein D
 10383
 0.26
chr17_61753634_61753814 0.19 LIMD2
 LIM domain containing 2
 22798
 0.13
chr10_50507704_50507855 0.19 C10orf71
 chromosome 10 open reading frame 71
 541
 0.55
chr5_135347344_135347609 0.19 TGFBI
 transforming growth factor, beta-induced, 68kDa
 17108
 0.2
chr6_37017148_37017362 0.19 COX6A1P2
 cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
 4648
 0.23
chr4_174202594_174202800 0.19 GALNT7
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
 10585
 0.17
chr22_26972149_26972362 0.19 TPST2
 tyrosylprotein sulfotransferase 2
 10563
 0.15
chr18_74769125_74769276 0.19 MBP
 myelin basic protein
 39466
 0.19
chr4_109901475_109901626 0.19 COL25A1
 collagen, type XXV, alpha 1
 156175
 0.04
chr2_64694768_64695032 0.19 LGALSL
 lectin, galactoside-binding-like
 13224
 0.19
chr7_50251693_50252080 0.19 AC020743.2
69467
 0.11
chr10_88117437_88117588 0.19 GRID1
 glutamate receptor, ionotropic, delta 1
 8723
 0.24
chr4_55557239_55557390 0.19 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 33229
 0.24
chr7_87944172_87944366 0.18 STEAP4
 STEAP family member 4
 8063
 0.23
chr20_20037098_20037366 0.18 C20orf26
 chromosome 20 open reading frame 26
 58
 0.9
chr1_21510914_21511065 0.18 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
 7612
 0.21
chr6_44585641_44585792 0.18 ENSG00000266619
 .
 182338
 0.03
chr6_159461301_159461469 0.18 TAGAP
 T-cell activation RhoGTPase activating protein
 4665
 0.21
chr11_33952668_33952907 0.18 LMO2
 LIM domain only 2 (rhombotin-like 1)
 38951
 0.16
chrX_128913033_128913442 0.18 SASH3
 SAM and SH3 domain containing 3
 723
 0.69
chr10_101940587_101940738 0.18 ERLIN1
 ER lipid raft associated 1
 5124
 0.15
chr3_126248151_126248302 0.18 CHST13
 carbohydrate (chondroitin 4) sulfotransferase 13
 5100
 0.16
chr17_72329157_72329308 0.18 KIF19
 kinesin family member 19
 6881
 0.11
chr4_55529764_55530043 0.18 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 5818
 0.34
chr9_135757349_135757570 0.18 C9orf9
 chromosome 9 open reading frame 9
 3174
 0.17
chr13_32691700_32692027 0.18 FRY
 furry homolog (Drosophila)
 56862
 0.14
chr21_46954664_46954827 0.18 SLC19A1
 solute carrier family 19 (folate transporter), member 1
 216
 0.95
chr11_75091839_75092030 0.18 RPS3
 ribosomal protein S3
 18596
 0.11
chr18_42882859_42883010 0.18 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 89974
 0.09
chr12_111618066_111618305 0.18 CUX2
 cut-like homeobox 2
 80935
 0.09
chr2_127818917_127819068 0.18 ENSG00000238788
 .
 43995
 0.16
chr10_11155205_11156000 0.18 CELF2-AS2
 CELF2 antisense RNA 2
 15166
 0.21
chr7_139585204_139585374 0.18 TBXAS1
 thromboxane A synthase 1 (platelet)
 56179
 0.14
chr8_70591137_70591370 0.18 ENSG00000222889
 .
 21206
 0.21
chr11_44938433_44938696 0.18 TSPAN18
 tetraspanin 18
 10606
 0.25
chr11_65084227_65084378 0.18 CDC42EP2
 CDC42 effector protein (Rho GTPase binding) 2
 211
 0.9
chr16_57712273_57712424 0.18 GPR97
 G protein-coupled receptor 97
 10128
 0.13
chr5_132644386_132644537 0.18 CTB-49A3.4
42184
 0.15
chr6_12659751_12659902 0.18 PHACTR1
 phosphatase and actin regulator 1
 58067
 0.15
chr19_35950537_35950782 0.17 FFAR2
 free fatty acid receptor 2
 10042
 0.11
chr9_135685079_135685230 0.17 RP11-295G24.5
39555
 0.12
chr4_144278414_144278571 0.17 ENSG00000265623
 .
 13879
 0.2
chr20_58566781_58566961 0.17 CDH26
 cadherin 26
 2710
 0.28
chr6_53600725_53601075 0.17 RP13-476E20.1
58172
 0.11
chr4_40310355_40310506 0.17 CHRNA9
 cholinergic receptor, nicotinic, alpha 9 (neuronal)
 26916
 0.19
chr5_108994298_108994449 0.17 ENSG00000266090
 .
 26908
 0.19
chr19_19653103_19653257 0.17 CILP2
 cartilage intermediate layer protein 2
 4106
 0.13
chr17_397150_397301 0.17 RP5-1029F21.3
9186
 0.19
chr2_238828434_238828585 0.17 UBE2F
 ubiquitin-conjugating enzyme E2F (putative)
 47088
 0.12
chr8_10053593_10053832 0.17 MSRA
 methionine sulfoxide reductase A
 100475
 0.07
chr16_68775300_68775451 0.17 ENSG00000200558
 .
 1008
 0.48
chr2_143909839_143910067 0.17 RP11-190J23.1
19788
 0.22
chr17_62032388_62032539 0.17 SCN4A
 sodium channel, voltage-gated, type IV, alpha subunit
 17815
 0.11
chr19_54885476_54885627 0.17 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 3386
 0.14
chr2_220074664_220075050 0.17 ZFAND2B
 zinc finger, AN1-type domain 2B
 1677
 0.16
chr1_44889322_44889516 0.17 RNF220
 ring finger protein 220
 293
 0.91
chr2_10815795_10815988 0.17 NOL10
 nucleolar protein 10
 4075
 0.21
chr7_29288155_29288306 0.17 AC004593.3
39644
 0.16
chr8_96087280_96087459 0.17 MIR3150A
 microRNA 3150a
 1959
 0.28
chr6_116784453_116784778 0.17 RP1-93H18.6
240
 0.83
chr6_6637501_6637686 0.17 LY86-AS1
 LY86 antisense RNA 1
 14589
 0.26
chr14_75152469_75152620 0.17 AREL1
 apoptosis resistant E3 ubiquitin protein ligase 1
 9626
 0.15
chr5_78204185_78204336 0.17 ARSB
 arylsulfatase B
 77348
 0.11
chr5_59560361_59560512 0.17 ENSG00000202017
 .
 39542
 0.2
chr19_46179501_46179652 0.17 ENSG00000207773
 .
 1390
 0.21
chr21_43845315_43845466 0.17 ENSG00000252619
 .
 7688
 0.14
chr4_82421002_82421153 0.17 RASGEF1B
 RasGEF domain family, member 1B
 28008
 0.26
chr1_45819749_45819900 0.17 ENSG00000238945
 .
 4596
 0.17
chrX_22015726_22015877 0.17 PHEX
 phosphate regulating endopeptidase homolog, X-linked
 34758
 0.17
chr5_148148648_148148804 0.17 ADRB2
 adrenoceptor beta 2, surface
 57430
 0.14
chr19_46005187_46005379 0.16 PPM1N
 protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
 2064
 0.19
chr16_81787336_81787487 0.16 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 14709
 0.27
chr10_114502069_114502220 0.16 RP11-25C19.3
64566
 0.12
chr3_32447849_32448023 0.16 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 14405
 0.24
chr7_41506541_41506692 0.16 INHBA-AS1
 INHBA antisense RNA 1
 226898
 0.02
chr20_2271241_2271392 0.16 TGM3
 transglutaminase 3
 5331
 0.27
chr2_221996968_221997119 0.16 EPHA4
 EPH receptor A4
 370237
 0.01
chr22_24525026_24525177 0.16 CABIN1
 calcineurin binding protein 1
 26705
 0.14
chr2_173998078_173998369 0.16 MLTK
 Mitogen-activated protein kinase kinase kinase MLT
 42876
 0.16
chr8_82030046_82030197 0.16 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 5818
 0.31
chr20_58653485_58653636 0.16 C20orf197
 chromosome 20 open reading frame 197
 22580
 0.23
chr2_232164549_232164700 0.16 ARMC9
 armadillo repeat containing 9
 29379
 0.17
chr6_5403263_5403414 0.16 FARS2
 phenylalanyl-tRNA synthetase 2, mitochondrial
 1437
 0.53
chr22_22889208_22889359 0.16 PRAME
 preferentially expressed antigen in melanoma
 7320
 0.07
chr10_99126345_99126553 0.16 RRP12
 ribosomal RNA processing 12 homolog (S. cerevisiae)
 24153
 0.09
chr3_140732457_140732639 0.16 SPSB4
 splA/ryanodine receptor domain and SOCS box containing 4
 37696
 0.16
chr5_66338060_66338433 0.16 MAST4
 microtubule associated serine/threonine kinase family member 4
 37763
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS3_TGIF2LX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0001562 response to protozoan(GO:0001562)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0097035 regulation of membrane lipid distribution(GO:0097035)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors