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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for MESP1

Z-value: 2.09

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Transcription factors associated with MESP1

Gene Symbol	Gene ID	Gene Info
MESP1 Ensembl NCBI GeneCards UniProt	ENSG00000166823.5	mesoderm posterior bHLH transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_90293229_90293732	MESP1	1061	0.387413	-0.62	7.4e-02	Click!
chr15_90283485_90283669	MESP1	10964	0.109677	-0.53	1.4e-01	Click!
chr15_90294508_90294785	MESP1	105	0.945722	-0.46	2.1e-01	Click!
chr15_90293741_90294016	MESP1	663	0.580099	-0.45	2.2e-01	Click!

Activity of the MESP1 motif across conditions

Conditions sorted by the z-value of the MESP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_159107_159571	5.16	ENSG00000199540	.	15027	0.14
chr11_63638814_63639520	4.77	MARK2	MAP/microtubule affinity-regulating kinase 2	2419	0.21
chr17_81008765_81009012	1.93	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	798	0.68
chr1_856648_857113	1.91	SAMD11	sterile alpha motif domain containing 11	3380	0.14
chr1_220863452_220864325	1.26	C1orf115	chromosome 1 open reading frame 115	701	0.71
chr19_14486268_14486999	1.19	CD97	CD97 molecule	5335	0.16
chr20_17631217_17631686	1.13	RRBP1	ribosome binding protein 1	9701	0.21
chr16_88220538_88220993	1.05	BANP	BTG3 associated nuclear protein	217141	0.02
chr19_891680_892010	1.05	MED16	mediator complex subunit 16	697	0.42
chr7_120633768_120634071	0.94	CPED1	cadherin-like and PC-esterase domain containing 1	4243	0.23
chr10_128555614_128555817	0.93	DOCK1	dedicator of cytokinesis 1	38263	0.18
chr17_80181799_80181950	0.91	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	4399	0.12
chr1_1207528_1208557	0.91	UBE2J2	ubiquitin-conjugating enzyme E2, J2	809	0.37
chr6_109561464_109561868	0.89	ENSG00000238474	.	50895	0.12
chr3_129323606_129323777	0.87	PLXND1	plexin D1	1970	0.3
chr5_172323723_172324191	0.86	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	8263	0.19
chr15_89658996_89659147	0.84	ENSG00000239151	.	4939	0.2
chr10_4584081_4584405	0.80	ENSG00000207124	.	27099	0.26
chr17_48281841_48281992	0.80	COL1A1	collagen, type I, alpha 1	2923	0.16
chr9_127049180_127049370	0.76	NEK6	NIMA-related kinase 6	556	0.76
chr1_235097341_235097798	0.75	ENSG00000239690	.	57636	0.14
chr19_18770845_18770996	0.75	KLHL26	kelch-like family member 26	23053	0.1
chr8_142424232_142425134	0.75	PTP4A3	protein tyrosine phosphatase type IVA, member 3	7324	0.13
chr19_6463883_6464309	0.74	CRB3	crumbs homolog 3 (Drosophila)	194	0.84
chr5_371573_371933	0.74	AHRR	aryl-hydrocarbon receptor repressor	28110	0.15
chr14_21541249_21541400	0.73	NDRG2	NDRG family member 2	2293	0.14
chr16_16190563_16190795	0.73	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	86966	0.07
chr17_79486044_79486605	0.73	RP13-766D20.2		258	0.83
chr10_134678084_134678235	0.72	TTC40	tetratricopeptide repeat domain 40	6923	0.27
chr7_47553727_47554138	0.70	TNS3	tensin 3	24943	0.26
chr5_179246518_179247261	0.69	SQSTM1	sequestosome 1	870	0.42
chr2_109787445_109787596	0.69	ENSG00000264934	.	29476	0.21
chr22_50061472_50061744	0.69	C22orf34	chromosome 22 open reading frame 34	10418	0.21
chr13_47049677_47049828	0.68	KIAA0226L	KIAA0226-like	37427	0.17
chr1_229992021_229992497	0.68	ENSG00000211525	.	192738	0.03
chr1_3565455_3566264	0.67	WRAP73	WD repeat containing, antisense to TP73	731	0.52
chr16_88838432_88838925	0.67	PIEZO1	piezo-type mechanosensitive ion channel component 1	12941	0.08
chr3_119456982_119457133	0.67	RP11-169N13.4		12140	0.17
chr10_80868705_80868856	0.67	ZMIZ1	zinc finger, MIZ-type containing 1	39988	0.18
chr17_9160012_9160446	0.66	RP11-85B7.4		26262	0.21
chr19_41329835_41330195	0.66	EGLN2	egl-9 family hypoxia-inducible factor 2	16867	0.11
chr19_4063421_4064204	0.66	CTD-2622I13.3		1065	0.34
chr10_94831581_94832316	0.66	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	1284	0.45
chr11_48161251_48161402	0.65	ENSG00000263693	.	42992	0.15
chr15_90577870_90579058	0.64	ENSG00000265871	.	28477	0.12
chr12_125340762_125340972	0.64	SCARB1	scavenger receptor class B, member 1	7462	0.22
chr11_1782922_1783382	0.64	CTSD	cathepsin D	382	0.64
chr5_5418968_5419119	0.64	KIAA0947	KIAA0947	3764	0.38
chr13_114883288_114883480	0.64	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	9089	0.22
chr19_48674183_48675124	0.63	C19orf68	chromosome 19 open reading frame 68	704	0.32
chr11_1145070_1145742	0.63	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	6174	0.2
chr6_3700969_3701120	0.63	PXDC1	PX domain containing 1	38084	0.17
chr8_21606262_21606413	0.62	GFRA2	GDNF family receptor alpha 2	39498	0.19
chr21_46713806_46714461	0.62	ENSG00000215447	.	6166	0.19
chr2_45581409_45581560	0.61	SRBD1	S1 RNA binding domain 1	213670	0.02
chr21_45628180_45628728	0.61	AP001057.1		7281	0.13
chr19_57182581_57182785	0.60	ZNF835	zinc finger protein 835	445	0.78
chr22_37310533_37310684	0.60	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	933	0.47
chr6_112366386_112366743	0.60	WISP3	WNT1 inducible signaling pathway protein 3	8711	0.21
chr14_61747742_61748391	0.59	TMEM30B	transmembrane protein 30B	107	0.63
chr16_1031936_1032355	0.58	SOX8	SRY (sex determining region Y)-box 8	337	0.64
chr1_39547729_39548144	0.57	MACF1	microtubule-actin crosslinking factor 1	847	0.61
chr1_88338043_88338194	0.56	ENSG00000199318	.	419062	0.01
chr7_98462704_98462855	0.56	TMEM130	transmembrane protein 130	1790	0.3
chr8_143111626_143111919	0.55	ENSG00000221123	.	84912	0.1
chr11_46321354_46321505	0.55	CREB3L1	cAMP responsive element binding protein 3-like 1	4752	0.19
chr15_99420909_99421157	0.54	IGF1R	insulin-like growth factor 1 receptor	12537	0.21
chr9_136821628_136822276	0.54	VAV2	vav 2 guanine nucleotide exchange factor	35451	0.17
chr7_32031191_32031342	0.54	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	79195	0.12
chr10_15391229_15391380	0.54	FAM171A1	family with sequence similarity 171, member A1	21754	0.25
chr7_73393570_73393847	0.54	ELN	elastin	48411	0.13
chr20_49440990_49441141	0.54	BCAS4	breast carcinoma amplified sequence 4	29458	0.14
chr10_101767083_101767324	0.54	DNMBP	dynamin binding protein	2473	0.28
chr13_51155690_51155841	0.54	ENSG00000221198	.	218392	0.02
chr3_48597793_48598316	0.53	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	508	0.63
chr13_32691700_32692027	0.53	FRY	furry homolog (Drosophila)	56862	0.14
chr10_135073598_135073855	0.53	MIR202HG	MIR202 host gene (non-protein coding)	12331	0.1
chr1_2206148_2206653	0.52	SKI	v-ski avian sarcoma viral oncogene homolog	46266	0.08
chr2_46119733_46119914	0.52	PRKCE	protein kinase C, epsilon	108218	0.07
chr20_10590260_10590411	0.52	JAG1	jagged 1	52819	0.15
chr16_89785407_89785795	0.52	VPS9D1	VPS9 domain containing 1	176	0.86
chr16_64474124_64474275	0.52	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	619382	0.0
chr8_98002610_98002912	0.52	CPQ	carboxypeptidase Q	38936	0.21
chr11_130671452_130671603	0.52	SNX19	sorting nexin 19	92242	0.09
chr7_81405925_81406300	0.52	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	6358	0.33
chr2_153469749_153469919	0.52	FMNL2	formin-like 2	6258	0.31
chr4_38871568_38871719	0.52	ENSG00000207944	.	1990	0.24
chr18_77550633_77550833	0.51	KCNG2	potassium voltage-gated channel, subfamily G, member 2	72935	0.1
chr13_114831463_114832357	0.51	RASA3	RAS p21 protein activator 3	11528	0.24
chr2_100218545_100218696	0.51	AFF3	AF4/FMR2 family, member 3	23788	0.23
chr1_239969599_239969857	0.51	ENSG00000233355	.	75963	0.1
chr9_35553068_35553219	0.51	FAM166B	family with sequence similarity 166, member B	10753	0.12
chr2_46122892_46123236	0.51	PRKCE	protein kinase C, epsilon	104977	0.07
chr17_76931207_76931358	0.51	TIMP2	TIMP metallopeptidase inhibitor 2	9813	0.15
chr1_201562896_201563143	0.51	AC096677.1	Uncharacterized protein ENSP00000471857	28994	0.14
chr14_52519690_52519841	0.51	NID2	nidogen 2 (osteonidogen)	14095	0.2
chr2_241524625_241525416	0.50	CAPN10-AS1	CAPN10 antisense RNA 1 (head to head)	1096	0.29
chr1_2209038_2209189	0.50	SKI	v-ski avian sarcoma viral oncogene homolog	48979	0.07
chr9_96720941_96721916	0.50	BARX1	BARX homeobox 1	3774	0.31
chr8_143695048_143695766	0.50	ARC	activity-regulated cytoskeleton-associated protein	1426	0.34
chr14_31343855_31344375	0.50	COCH	cochlin	145	0.96
chr8_145582794_145583566	0.50	SLC52A2	solute carrier family 52 (riboflavin transporter), member 2	337	0.64
chr5_139049687_139050600	0.49	CXXC5	CXXC finger protein 5	4878	0.24
chr19_1947618_1948192	0.49	CSNK1G2	casein kinase 1, gamma 2	5441	0.11
chr8_25641956_25642107	0.49	EBF2	early B-cell factor 2	103401	0.08
chr9_137366473_137366866	0.49	RXRA	retinoid X receptor, alpha	68241	0.11
chr15_42213065_42213339	0.49	CTD-2382E5.4		413	0.76
chr4_2819205_2819714	0.49	SH3BP2	SH3-domain binding protein 2	453	0.83
chr4_77659083_77659234	0.49	RP11-359D14.2		20469	0.2
chr11_72896529_72896905	0.48	RP11-800A3.2		30241	0.13
chr20_30743365_30743658	0.48	ENSG00000265736	.	36957	0.11
chr20_46296022_46296173	0.48	SULF2	sulfatase 2	2094	0.35
chr11_74385068_74385219	0.48	ENSG00000223202	.	11126	0.14
chr16_28123287_28123438	0.48	XPO6	exportin 6	151	0.96
chr8_144611605_144612253	0.48	ZC3H3	zinc finger CCCH-type containing 3	11694	0.08
chr19_15559479_15560330	0.48	ENSG00000269782	.	455	0.47
chr8_145150393_145151259	0.48	CYC1	cytochrome c-1	896	0.32
chr19_16482714_16483205	0.47	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	10195	0.15
chr16_85862487_85862638	0.47	COX4I1	cytochrome c oxidase subunit IV isoform 1	27754	0.11
chr19_47218553_47219361	0.47	PRKD2	protein kinase D2	896	0.37
chr1_150244620_150245106	0.47	C1orf54	chromosome 1 open reading frame 54	239	0.83
chr11_61448106_61448684	0.47	DAGLA	diacylglycerol lipase, alpha	490	0.8
chr12_109097534_109097685	0.47	CORO1C	coronin, actin binding protein, 1C	758	0.61
chr16_2084525_2084950	0.47	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	1465	0.15
chr5_15619947_15620098	0.47	FBXL7	F-box and leucine-rich repeat protein 7	3931	0.29
chr7_492646_493023	0.47	PDGFA	platelet-derived growth factor alpha polypeptide	65311	0.11
chr11_75539152_75539402	0.47	ENSG00000200256	.	7091	0.11
chr1_244014136_244014917	0.47	AKT3	v-akt murine thymoma viral oncogene homolog 3	145	0.97
chr15_70451790_70452201	0.47	ENSG00000200216	.	33580	0.2
chr6_151151372_151151523	0.47	MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	35238	0.2
chr1_206867494_206867645	0.47	MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	9187	0.15
chr5_10856625_10856780	0.47	CTD-2154B17.4		88966	0.09
chr6_62995936_62996087	0.46	KHDRBS2	KH domain containing, RNA binding, signal transduction associated 2	121	0.98
chr16_21552235_21552606	0.46	ENSG00000265462	.	34964	0.11
chr21_46825889_46826320	0.46	COL18A1	collagen, type XVIII, alpha 1	1052	0.46
chr18_20807902_20808053	0.45	RP11-17J14.2		32341	0.18
chr17_81042798_81042949	0.45	METRNL	meteorin, glial cell differentiation regulator-like	924	0.64
chr9_112942282_112942517	0.45	C9orf152	chromosome 9 open reading frame 152	28070	0.2
chr5_378642_378793	0.45	AHRR	aryl-hydrocarbon receptor repressor	35074	0.13
chr20_48273054_48273287	0.45	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	57245	0.1
chr11_47628458_47628609	0.45	ENSG00000223187	.	8013	0.09
chr1_54705038_54705327	0.45	SSBP3-AS1	SSBP3 antisense RNA 1	1472	0.33
chr10_104363048_104363335	0.45	ENSG00000207029	.	11910	0.16
chr8_37468731_37468882	0.45	ENSG00000223215	.	57610	0.1
chr1_156465621_156466169	0.45	MEF2D	myocyte enhancer factor 2D	4634	0.14
chr10_60367808_60368127	0.44	BICC1	bicaudal C homolog 1 (Drosophila)	95067	0.09
chr1_52435800_52436083	0.44	ENSG00000200839	.	3141	0.18
chr9_116321878_116322160	0.44	RGS3	regulator of G-protein signaling 3	5342	0.25
chr3_87003421_87003572	0.44	VGLL3	vestigial like 3 (Drosophila)	36356	0.24
chr6_52530721_52530872	0.44	RP1-152L7.5		724	0.69
chr1_66291138_66291289	0.43	PDE4B	phosphodiesterase 4B, cAMP-specific	32349	0.21
chr10_6424528_6424998	0.43	DKFZP667F0711		32485	0.21
chr12_66356249_66356432	0.43	RP11-366L20.3		14081	0.2
chr8_71515545_71515696	0.43	ENSG00000238450	.	1147	0.39
chr7_2649043_2649378	0.43	IQCE	IQ motif containing E	12677	0.16
chr18_74075767_74075918	0.43	RP11-504I13.3		8830	0.23
chr16_87617546_87617733	0.43	RP11-482M8.3		18157	0.18
chr6_7975972_7976313	0.42	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	50504	0.16
chr6_167166191_167166750	0.42	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	4929	0.31
chr11_1146453_1147024	0.42	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	4842	0.22
chr4_189898416_189898567	0.42	ENSG00000252275	.	260612	0.02
chr18_46443764_46443965	0.42	SMAD7	SMAD family member 7	31011	0.2
chr3_55002284_55002644	0.42	LRTM1	leucine-rich repeats and transmembrane domains 1	1349	0.59
chr6_82477389_82477689	0.42	ENSG00000206886	.	3798	0.25
chr9_8365982_8366133	0.42	RP11-134K1.3		335495	0.01
chr9_139549895_139550191	0.42	EGFL7	EGF-like-domain, multiple 7	3265	0.12
chr3_114618572_114618723	0.42	ZBTB20	zinc finger and BTB domain containing 20	140529	0.05
chr11_126215235_126215450	0.42	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	10213	0.14
chr22_50962768_50963586	0.42	CTA-384D8.36		822	0.26
chr1_61400830_61400981	0.42	RP4-668G5.1		17616	0.26
chr1_40310608_40311589	0.42	ENSG00000202222	.	36252	0.1
chr16_83847971_83848200	0.42	HSBP1	heat shock factor binding protein 1	6491	0.17
chr14_105188331_105188482	0.42	ADSSL1	adenylosuccinate synthase like 1	2117	0.22
chr14_54469720_54469871	0.41	BMP4	bone morphogenetic protein 4	44316	0.18
chr9_116106360_116106630	0.41	WDR31	WD repeat domain 31	3917	0.15
chr1_35294200_35294351	0.41	RP5-997D16.2		22020	0.11
chr8_144513420_144513883	0.41	MAFA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	1075	0.37
chr2_40406323_40406570	0.41	SLC8A1-AS1	SLC8A1 antisense RNA 1	30659	0.24
chr5_138363011_138363258	0.41	CTB-46B19.2		14795	0.16
chr12_12813280_12813431	0.41	GPR19	G protein-coupled receptor 19	24100	0.15
chr12_54873126_54873277	0.41	GTSF1	gametocyte specific factor 1	5818	0.15
chr17_81146535_81146986	0.41	METRNL	meteorin, glial cell differentiation regulator-like	94766	0.08
chr1_246947982_246948246	0.41	ENSG00000227953	.	5812	0.17
chr17_48275477_48275628	0.41	COL1A1	collagen, type I, alpha 1	2000	0.21
chr3_140795482_140795742	0.41	SPSB4	splA/ryanodine receptor domain and SOCS box containing 4	25368	0.21
chr9_97623840_97624643	0.41	RP11-49O14.3		37687	0.13
chr3_123337794_123338198	0.41	MYLK	myosin light chain kinase	1365	0.44
chr7_37123352_37123539	0.41	ENSG00000221157	.	21770	0.22
chr5_368374_368533	0.41	AHRR	aryl-hydrocarbon receptor repressor	24810	0.15
chr7_47518521_47518775	0.41	TNS3	tensin 3	2235	0.46
chr22_50061068_50061417	0.41	C22orf34	chromosome 22 open reading frame 34	10052	0.21
chr12_110310303_110310470	0.41	ENSG00000241413	.	6072	0.15
chr12_54622035_54622202	0.40	ENSG00000265371	.	3142	0.13
chr16_579210_579823	0.40	CAPN15	calpain 15	1660	0.18
chr7_73308405_73308556	0.40	WBSCR28	Williams-Beuren syndrome chromosome region 28	32991	0.14
chr11_123430554_123430784	0.40	GRAMD1B	GRAM domain containing 1B	301	0.93
chr3_171690538_171690732	0.40	FNDC3B	fibronectin type III domain containing 3B	66783	0.11
chr16_70737707_70738175	0.40	VAC14	Vac14 homolog (S. cerevisiae)	3793	0.18
chr2_197345751_197345902	0.40	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	111509	0.06
chr15_31558952_31559841	0.40	KLF13	Kruppel-like factor 13	59662	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	1.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.5	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.2	0.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.2	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2	0.5	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	1.0	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.1	0.4	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.5	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.5	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.5	GO:0015705	iodide transport(GO:0015705)
0.1	0.4	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.4	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.4	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.2	GO:0051014	actin filament severing(GO:0051014)
0.1	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.5	GO:0034063	stress granule assembly(GO:0034063)
0.1	1.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.7	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.8	GO:0034505	tooth mineralization(GO:0034505)
0.1	0.2	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.4	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.3	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.3	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.4	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0009405	pathogenesis(GO:0009405)
0.1	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.2	GO:0033622	integrin activation(GO:0033622)
0.1	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.2	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	0.2	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.2	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.3	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.3	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1	0.7	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	1.5	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.3	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.2	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.2	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.2	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1	0.3	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.7	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.2	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.2	GO:0002830	positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.1	0.2	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.2	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.1	0.3	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.1	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.1	0.5	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.1	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.1	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.1	GO:0048478	replication fork protection(GO:0048478)
0.1	0.2	GO:0046113	nucleobase catabolic process(GO:0046113)
0.1	0.3	GO:0008228	opsonization(GO:0008228)
0.1	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.2	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1	0.3	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.1	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0042428	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.1	0.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.3	GO:0021548	pons development(GO:0021548)
0.1	0.1	GO:0070849	response to epidermal growth factor(GO:0070849)
0.1	0.3	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.1	0.3	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.1	0.3	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.3	GO:0016265	obsolete death(GO:0016265)
0.0	0.3	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.4	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0001562	response to protozoan(GO:0001562)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.3	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0045628	regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.1	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.4	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.2	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.2	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.2	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.4	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.2	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0018101	protein citrullination(GO:0018101)
0.0	0.5	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.5	GO:0015879	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.2	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0060571	morphogenesis of an epithelial fold(GO:0060571)
0.0	0.1	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	1.0	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.2	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.0	0.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.5	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.3	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.4	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.2	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0090102	cochlea development(GO:0090102)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.4	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.1	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.6	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.2	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0060688	regulation of morphogenesis of a branching structure(GO:0060688)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.2	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.4	GO:0045446	endothelial cell differentiation(GO:0045446)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.3	GO:0009268	response to pH(GO:0009268)
0.0	0.5	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.0	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0042033	chemokine biosynthetic process(GO:0042033) chemokine metabolic process(GO:0050755)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.6	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.2	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0060535	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.0	GO:0034442	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.4	GO:0043297	apical junction assembly(GO:0043297)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:1902913	positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.2	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.3	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.4	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.2	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0014848	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0050706	positive regulation of interleukin-1 beta production(GO:0032731) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.0	GO:0060073	micturition(GO:0060073)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	0.1	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0050873	brown fat cell differentiation(GO:0050873)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	0.6	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.1	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.3	GO:0030904	retromer complex(GO:0030904)
0.1	0.3	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) complex of collagen trimers(GO:0098644)
0.1	0.5	GO:0043205	fibril(GO:0043205)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.4	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	1.7	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.8	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0030990	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.4	GO:0031514	motile cilium(GO:0031514)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	1.5	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	1.0	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.0	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	2.9	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0005924	cell-substrate adherens junction(GO:0005924)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.8	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.4	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.6	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.3	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.4	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.3	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.1	GO:0070052	collagen V binding(GO:0070052)
0.1	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.7	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.3	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.2	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.5	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	0.2	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.5	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.1	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	0.2	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.4	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.4	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.5	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.1	0.2	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.1	0.4	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.6	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.5	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.7	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.4	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.3	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.4	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.2	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.0	0.2	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.4	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.4	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	1.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.0	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.3	GO:0042562	hormone binding(GO:0042562)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	3.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	2.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	2.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME IMMUNE SYSTEM	Genes involved in Immune System
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex

Results for MESP1

Z-value: 2.09

Motif logo

Transcription factors associated with MESP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MESP1 motif across conditions

Conditions sorted by the z-value of the MESP1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: