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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MSX1

Z-value: 1.28

Motif logo

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Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
MSX1
ENSG00000163132.6 msh homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_4862740_4862954MSX114540.530254-0.817.9e-03Click!
chr4_4860648_4860832MSX16530.801189-0.808.9e-03Click!
chr4_4857303_4857507MSX139880.321058-0.751.9e-02Click!
chr4_4793701_4793852MSX1676170.1252120.722.7e-02Click!
chr4_4862254_4862686MSX110770.636089-0.608.5e-02Click!

Activity of the MSX1 motif across conditions

Conditions sorted by the z-value of the MSX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_93221945_93222246 0.65 HECTD2
 HECT domain containing E3 ubiquitin protein ligase 2
 198
 0.97
chr7_116416400_116416551 0.60 MET
 met proto-oncogene
 754
 0.71
chr1_206593311_206593758 0.59 SRGAP2
 SLIT-ROBO Rho GTPase activating protein 2
 13798
 0.17
chr14_69015594_69016105 0.55 CTD-2325P2.4
79313
 0.1
chr9_4137653_4137928 0.48 GLIS3
 GLIS family zinc finger 3
 7403
 0.28
chr8_41906632_41907752 0.47 KAT6A
 K(lysine) acetyltransferase 6A
 2313
 0.3
chr18_12598337_12598791 0.45 SPIRE1
 spire-type actin nucleation factor 1
 54520
 0.09
chr17_46080195_46080690 0.45 RP11-6N17.10
6880
 0.1
chr3_152787726_152787975 0.44 RP11-529G21.2
91714
 0.08
chr5_9622384_9622535 0.43 TAS2R1
 taste receptor, type 2, member 1
 8004
 0.22
chr14_35629047_35629198 0.43 KIAA0391
 KIAA0391
 37157
 0.15
chr14_72179521_72179805 0.43 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 94190
 0.09
chr11_9927954_9928253 0.42 ENSG00000252568
 .
 62680
 0.11
chr13_77518573_77518724 0.41 IRG1
 immunoresponsive 1 homolog (mouse)
 3984
 0.24
chr4_78502666_78502963 0.41 CXCL13
 chemokine (C-X-C motif) ligand 13
 69907
 0.13
chr10_75987768_75988344 0.40 ADK
 adenosine kinase
 51535
 0.15
chr13_31440489_31440640 0.40 MEDAG
 mesenteric estrogen-dependent adipogenesis
 39764
 0.16
chr15_101143578_101144308 0.40 ASB7
 ankyrin repeat and SOCS box containing 7
 1129
 0.36
chr6_2103859_2104525 0.39 GMDS
 GDP-mannose 4,6-dehydratase
 72033
 0.13
chr3_111820782_111820933 0.39 ENSG00000207940
 .
 10791
 0.15
chr7_101457741_101458764 0.39 CUX1
 cut-like homeobox 1
 707
 0.73
chr7_46949633_46949784 0.38 AC011294.3
 Uncharacterized protein
 212988
 0.03
chr16_18980279_18980782 0.38 TMC7
 transmembrane channel-like 7
 14726
 0.14
chr5_110849348_110849548 0.38 STARD4
 StAR-related lipid transfer (START) domain containing 4
 1160
 0.42
chr14_42683704_42683855 0.38 ENSG00000222084
 .
 86175
 0.1
chr4_146467395_146467619 0.38 SMAD1-AS1
 SMAD1 antisense RNA 1
 29237
 0.17
chr5_66356025_66356176 0.38 MAST4
 microtubule associated serine/threonine kinase family member 4
 55617
 0.15
chr4_170582263_170582414 0.37 CLCN3
 chloride channel, voltage-sensitive 3
 1125
 0.6
chr22_26717807_26718076 0.37 SEZ6L
 seizure related 6 homolog (mouse)-like
 25740
 0.18
chr2_227312371_227312522 0.37 ENSG00000263363
 .
 211063
 0.02
chr13_103360569_103360720 0.37 ENSG00000238869
 .
 13508
 0.13
chr3_188251532_188251683 0.37 LPP-AS1
 LPP antisense RNA 1
 34847
 0.2
chr7_116347170_116347321 0.37 MET
 met proto-oncogene
 8106
 0.26
chr12_109195761_109195912 0.37 ENSG00000264043
 .
 23789
 0.13
chr5_34052813_34052964 0.37 C1QTNF3
 C1q and tumor necrosis factor related protein 3
 8951
 0.23
chr17_60897719_60897987 0.37 MARCH10
 membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
 12148
 0.25
chr7_42030328_42030605 0.36 GLI3
 GLI family zinc finger 3
 236854
 0.02
chr19_13147341_13147492 0.36 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 11605
 0.1
chr12_91290582_91290865 0.36 CCER1
 coiled-coil glutamate-rich protein 1
 58230
 0.15
chr1_234754493_234754778 0.35 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 9364
 0.19
chr2_47006358_47006650 0.35 LINC01118
 long intergenic non-protein coding RNA 1118
 37318
 0.13
chr20_44409069_44409220 0.35 ENSG00000221046
 .
 1807
 0.19
chr17_32580574_32580862 0.34 CCL2
 chemokine (C-C motif) ligand 2
 1586
 0.24
chr15_78594610_78594888 0.34 WDR61
 WD repeat domain 61
 2613
 0.18
chr6_139729934_139730085 0.34 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 34252
 0.22
chr9_111235960_111236111 0.34 ENSG00000222512
 .
 114826
 0.07
chr4_157860965_157861230 0.34 PDGFC
 platelet derived growth factor C
 30958
 0.19
chr10_60420713_60420913 0.34 BICC1
 bicaudal C homolog 1 (Drosophila)
 132482
 0.05
chr1_224076219_224076370 0.34 TP53BP2
 tumor protein p53 binding protein, 2
 42620
 0.17
chr4_139232146_139232297 0.34 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 68718
 0.14
chr5_53683581_53683732 0.33 HSPB3
 heat shock 27kDa protein 3
 67789
 0.12
chr3_114959246_114959397 0.33 ZBTB20
 zinc finger and BTB domain containing 20
 93203
 0.1
chr3_12550506_12550657 0.33 ENSG00000200114
 .
 2131
 0.22
chr10_95202028_95202179 0.33 MYOF
 myoferlin
 39848
 0.15
chr9_111207476_111207627 0.33 ENSG00000222512
 .
 86342
 0.11
chr1_113088087_113088238 0.33 RP4-671G15.2
27099
 0.14
chr6_37850154_37850385 0.33 ENSG00000200597
 .
 33080
 0.16
chr1_224820105_224820256 0.33 CNIH3
 cornichon family AMPA receptor auxiliary protein 3
 16185
 0.19
chr22_28144785_28145032 0.32 RP11-375H17.1
32440
 0.2
chr1_8106369_8106520 0.32 ERRFI1
 ERBB receptor feedback inhibitor 1
 20076
 0.2
chr7_102477303_102477454 0.32 ENSG00000252643
 .
 2326
 0.29
chr2_150601107_150601258 0.32 ENSG00000207270
 .
 133894
 0.05
chr6_72113075_72113298 0.32 ENSG00000207827
 .
 138
 0.97
chr3_8979557_8979708 0.32 ENSG00000199815
 .
 6453
 0.22
chr10_63734512_63734894 0.32 ENSG00000221272
 .
 47926
 0.17
chr21_30331573_30331724 0.32 LTN1
 listerin E3 ubiquitin protein ligase 1
 33558
 0.14
chr2_224950724_224950875 0.32 SERPINE2
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
 46763
 0.17
chr2_38918276_38918577 0.32 GALM
 galactose mutarotase (aldose 1-epimerase)
 9989
 0.17
chr11_130451238_130451517 0.32 C11orf44
 chromosome 11 open reading frame 44
 91474
 0.09
chr7_80512457_80512608 0.32 SEMA3C
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
 35967
 0.24
chr16_54960016_54960167 0.32 IRX5
 iroquois homeobox 5
 4683
 0.36
chr11_46071541_46071813 0.31 PHF21A
 PHD finger protein 21A
 42079
 0.15
chrX_24166137_24167088 0.31 ZFX
 zinc finger protein, X-linked
 1134
 0.35
chr3_81474618_81474769 0.31 ENSG00000222389
 .
 83934
 0.11
chr11_102321739_102322277 0.31 TMEM123
 transmembrane protein 123
 46
 0.96
chr3_16024682_16024833 0.31 ENSG00000207815
 .
 109479
 0.06
chr7_151190654_151190805 0.31 RHEB
 Ras homolog enriched in brain
 24426
 0.13
chr20_36815816_36815967 0.31 TGM2
 transglutaminase 2
 20911
 0.17
chr5_72713863_72714014 0.31 FOXD1
 forkhead box D1
 30414
 0.18
chr2_225543203_225543354 0.31 CUL3
 cullin 3
 93168
 0.09
chr12_45627192_45627343 0.31 ANO6
 anoctamin 6
 17364
 0.28
chr15_90950843_90951750 0.31 RP11-154B12.3
10183
 0.16
chr5_73497876_73498136 0.31 ENSG00000222551
 .
 69584
 0.13
chr2_242318504_242318655 0.31 FARP2
 FERM, RhoGEF and pleckstrin domain protein 2
 6315
 0.17
chr10_65024052_65024675 0.31 JMJD1C
 jumonji domain containing 1C
 4463
 0.31
chr11_121532407_121532558 0.30 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 71354
 0.13
chr1_172290576_172290727 0.30 ENSG00000252354
 .
 26632
 0.17
chr9_14281034_14281328 0.30 NFIB
 nuclear factor I/B
 26831
 0.22
chr6_52289660_52289856 0.30 EFHC1
 EF-hand domain (C-terminal) containing 1
 1288
 0.54
chr9_81321983_81322311 0.30 PSAT1
 phosphoserine aminotransferase 1
 410088
 0.01
chr10_50760988_50761139 0.30 ERCC6
 excision repair cross-complementing rodent repair deficiency, complementation group 6
 13479
 0.15
chr13_47207440_47207736 0.30 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 46383
 0.18
chrX_45570754_45570905 0.30 ENSG00000207870
 .
 34865
 0.19
chr13_45294845_45294996 0.30 ENSG00000238932
 .
 92111
 0.09
chr10_117532445_117532596 0.30 ATRNL1
 attractin-like 1
 471037
 0.01
chr12_89339824_89340184 0.30 ENSG00000238302
 .
 336058
 0.01
chr4_152277546_152277697 0.30 FAM160A1
 family with sequence similarity 160, member A1
 52777
 0.13
chr2_65581901_65582416 0.30 SPRED2
 sprouty-related, EVH1 domain containing 2
 10238
 0.23
chr9_137251018_137251277 0.30 ENSG00000263897
 .
 20110
 0.22
chr4_174132836_174132987 0.30 RP11-10K16.1
42108
 0.13
chr11_96059054_96059205 0.30 ENSG00000266192
 .
 15473
 0.19
chr5_153826475_153827364 0.30 SAP30L
 SAP30-like
 814
 0.51
chr3_97636799_97636950 0.30 CRYBG3
 beta-gamma crystallin domain containing 3
 6182
 0.25
chr12_58923583_58923734 0.30 RP11-362K2.2
 Protein LOC100506869
 14249
 0.3
chr4_184558434_184558585 0.30 ENSG00000252157
 .
 16320
 0.14
chr17_39222775_39222926 0.30 KRTAP2-4
 keratin associated protein 2-4
 719
 0.36
chr17_53804938_53805089 0.30 TMEM100
 transmembrane protein 100
 4469
 0.29
chr13_107156553_107156704 0.30 EFNB2
 ephrin-B2
 30834
 0.23
chr2_43941438_43941589 0.30 ENSG00000252490
 .
 57976
 0.11
chr14_100376837_100376988 0.30 EML1
 echinoderm microtubule associated protein like 1
 12342
 0.2
chr7_80350905_80351077 0.30 CD36
 CD36 molecule (thrombospondin receptor)
 48299
 0.19
chr8_42409885_42410036 0.29 SMIM19
 small integral membrane protein 19
 8389
 0.18
chr4_14728667_14728818 0.29 ENSG00000202449
 .
 36408
 0.24
chr7_29662924_29663075 0.29 DPY19L2P3
 DPY19L2 pseudogene 3
 26844
 0.17
chr6_121988152_121988303 0.29 ENSG00000222659
 .
 86560
 0.1
chr9_74299304_74300206 0.29 TMEM2
 transmembrane protein 2
 20093
 0.28
chr16_24742094_24743166 0.29 TNRC6A
 trinucleotide repeat containing 6A
 1596
 0.5
chr2_68420623_68420967 0.29 RP11-474G23.2
13830
 0.14
chr4_148693217_148693552 0.29 ENSG00000264274
 .
 10362
 0.18
chr5_136117041_136117192 0.29 ENSG00000222285
 .
 187879
 0.03
chr12_64565372_64565523 0.29 RP11-196H14.3
23810
 0.14
chr11_13310143_13310461 0.29 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 10870
 0.27
chr3_187985246_187985463 0.29 LPP
 LIM domain containing preferred translocation partner in lipoma
 27702
 0.23
chr17_26610027_26610178 0.29 ENSG00000207844
 .
 6523
 0.1
chr3_156469526_156469677 0.29 TIPARP
 TCDD-inducible poly(ADP-ribose) polymerase
 70646
 0.1
chr21_18145527_18145678 0.29 ENSG00000239023
 .
 54285
 0.17
chr8_89288937_89289088 0.28 RP11-586K2.1
50053
 0.16
chr12_52604417_52604648 0.28 KRT80
 keratin 80
 18748
 0.1
chr9_21590451_21590602 0.28 MIR31HG
 MIR31 host gene (non-protein coding)
 30858
 0.16
chr4_140958813_140959347 0.28 RP11-392B6.1
90089
 0.09
chr1_199825379_199825530 0.28 ENSG00000200139
 .
 31833
 0.23
chr14_94839858_94840009 0.28 SERPINA1
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
 14993
 0.18
chr12_132267707_132268092 0.28 ENSG00000200516
 .
 18080
 0.16
chr11_123089847_123089998 0.28 CLMP
 CXADR-like membrane protein
 23933
 0.18
chr12_6332006_6332305 0.28 ENSG00000202318
 .
 11466
 0.17
chr8_141734362_141734513 0.28 PTK2
 protein tyrosine kinase 2
 2550
 0.32
chr4_169330808_169330959 0.28 DDX60L
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
 8754
 0.24
chr11_108742969_108743120 0.28 ENSG00000201243
 .
 133200
 0.05
chr10_95236478_95236629 0.28 MYOF
 myoferlin
 5398
 0.21
chr4_126245178_126245329 0.28 FAT4
 FAT atypical cadherin 4
 7699
 0.29
chr3_188067044_188067254 0.28 LPP
 LIM domain containing preferred translocation partner in lipoma
 109497
 0.07
chr8_25771009_25771433 0.28 EBF2
 early B-cell factor 2
 25789
 0.27
chr4_187597285_187597436 0.28 FAT1
 FAT atypical cadherin 1
 47649
 0.17
chr3_17719701_17719852 0.28 ENSG00000271841
 .
 13321
 0.25
chr12_107256430_107256581 0.28 RP11-144F15.1
 Uncharacterized protein
 87809
 0.07
chr7_129304567_129304757 0.28 NRF1
 nuclear respiratory factor 1
 7471
 0.24
chr2_48571922_48572463 0.28 ENSG00000251889
 .
 4227
 0.27
chr14_52001291_52001686 0.28 ENSG00000252400
 .
 11906
 0.22
chr21_39664180_39664501 0.28 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 4139
 0.33
chr2_147739330_147739481 0.28 ENSG00000238860
 .
 342134
 0.01
chr12_32748094_32748245 0.28 FGD4
 FYVE, RhoGEF and PH domain containing 4
 3291
 0.33
chr11_114224456_114224725 0.28 RP11-64D24.2
2703
 0.24
chr6_52382258_52382409 0.28 TRAM2
 translocation associated membrane protein 2
 59380
 0.12
chr5_57483908_57484059 0.28 ENSG00000238899
 .
 117968
 0.07
chr17_27574011_27574162 0.28 CRYBA1
 crystallin, beta A1
 205
 0.94
chr7_18809523_18809674 0.28 ENSG00000222164
 .
 38304
 0.21
chr14_78060038_78060870 0.28 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
 3210
 0.25
chr7_77496191_77496692 0.28 PHTF2
 putative homeodomain transcription factor 2
 26944
 0.18
chr1_98793274_98793457 0.28 ENSG00000221777
 .
 45576
 0.21
chr1_202251770_202252122 0.28 ENSG00000239046
 .
 51154
 0.1
chr15_60699546_60699697 0.28 ANXA2
 annexin A2
 4539
 0.29
chr2_225955794_225955945 0.28 DOCK10
 dedicator of cytokinesis 10
 48710
 0.18
chr8_67472669_67472820 0.28 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 52398
 0.1
chr13_76299059_76299210 0.28 LMO7
 LIM domain 7
 35369
 0.19
chr5_86453164_86453315 0.27 ENSG00000265919
 .
 42468
 0.15
chr13_76867098_76867386 0.27 ENSG00000243274
 .
 158175
 0.04
chr7_80127442_80127593 0.27 GNAT3
 guanine nucleotide binding protein, alpha transducing 3
 13819
 0.27
chr11_27407572_27407723 0.27 CCDC34
 coiled-coil domain containing 34
 22232
 0.21
chr10_89435270_89435421 0.27 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
 14637
 0.2
chr3_58034413_58034564 0.27 FLNB
 filamin B, beta
 29568
 0.21
chr11_35606785_35606936 0.27 FJX1
 four jointed box 1 (Drosophila)
 32875
 0.18
chr6_53389704_53389855 0.27 GCLC
 glutamate-cysteine ligase, catalytic subunit
 1657
 0.39
chr9_83643160_83643311 0.27 ENSG00000221581
 .
 293991
 0.01
chr2_55327280_55327923 0.27 ENSG00000266376
 .
 8245
 0.2
chr9_134918134_134918364 0.27 MED27
 mediator complex subunit 27
 37004
 0.2
chr11_130717130_130717402 0.27 SNX19
 sorting nexin 19
 46503
 0.19
chr20_46815691_46815842 0.27 ENSG00000252227
 .
 51000
 0.18
chr14_59804366_59804548 0.27 ENSG00000252869
 .
 62284
 0.12
chr1_206164682_206164833 0.27 FAM72A
 family with sequence similarity 72, member A
 25846
 0.15
chr1_157977722_157977873 0.27 KIRREL
 kin of IRRE like (Drosophila)
 14362
 0.2
chr9_38026523_38026674 0.27 SHB
 Src homology 2 domain containing adaptor protein B
 42610
 0.17
chr6_163777027_163777374 0.27 QKI
 QKI, KH domain containing, RNA binding
 58475
 0.16
chr14_74724538_74725207 0.27 VSX2
 visual system homeobox 2
 18697
 0.14
chr5_39072103_39073220 0.27 RICTOR
 RPTOR independent companion of MTOR, complex 2
 1830
 0.43
chr20_11910800_11911092 0.27 BTBD3
 BTB (POZ) domain containing 3
 11447
 0.24
chr10_4808545_4809063 0.27 AKR1E2
 aldo-keto reductase family 1, member E2
 20017
 0.25
chr10_60462562_60462713 0.27 BICC1
 bicaudal C homolog 1 (Drosophila)
 90658
 0.1
chr13_46074470_46074652 0.26 COG3
 component of oligomeric golgi complex 3
 35501
 0.15
chr13_43843628_43843779 0.26 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 91510
 0.1
chr5_14806397_14806548 0.26 ENSG00000264792
 .
 19649
 0.23
chr1_51127497_51127778 0.26 FAF1
 Fas (TNFRSF6) associated factor 1
 49467
 0.15
chr1_94269708_94269859 0.26 RP11-488P3.1
28783
 0.16
chr12_120620090_120620241 0.26 ENSG00000263913
 .
 10235
 0.11
chr9_16031215_16031463 0.26 C9orf92
 chromosome 9 open reading frame 92
 184558
 0.03
chr1_87174228_87174695 0.26 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 3883
 0.2
chr17_40554278_40554429 0.26 ENSG00000221020
 .
 3326
 0.15
chr4_159080194_159080345 0.26 FAM198B
 family with sequence similarity 198, member B
 564
 0.76
chr3_99750954_99751105 0.26 ENSG00000264897
 .
 67787
 0.11
chr3_11550931_11551082 0.26 VGLL4
 vestigial like 4 (Drosophila)
 59392
 0.14
chr2_33589041_33589192 0.26 ENSG00000252246
 .
 31151
 0.19

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071436 sodium ion export(GO:0071436)
0.1 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.2 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.0 GO:0071071 regulation of phospholipid biosynthetic process(GO:0071071)
0.0 0.2 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.0 GO:0060592 mammary gland formation(GO:0060592) mammary placode formation(GO:0060596)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.0 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.0 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.0 GO:0036445 forebrain neuroblast division(GO:0021873) neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.0 GO:2000649 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:0090200 positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.0 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0060179 male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.0 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.0 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0002385 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0090504 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.0 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0048019 receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019)
0.0 0.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion