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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for MSX2

Z-value: 1.03

Motif logo

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Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
MSX2
ENSG00000120149.7 msh homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_174151057_174151248MSX23840.9061820.818.5e-03Click!
chr5_173916383_173916534MSX22350780.019896-0.693.8e-02Click!
chr5_173918124_173918275MSX22333370.020178-0.694.1e-02Click!
chr5_173888101_173888252MSX22633600.0160230.674.6e-02Click!
chr5_173882231_173882382MSX22692300.0153510.674.6e-02Click!

Activity of the MSX2 motif across conditions

Conditions sorted by the z-value of the MSX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_64419641_64419918 0.70 RP11-4F22.2
6807
 0.26
chr18_59619334_59619485 0.65 RNF152
 ring finger protein 152
 57945
 0.16
chr3_17274716_17274867 0.60 ENSG00000252976
 .
 97577
 0.08
chr2_235231609_235231760 0.56 ARL4C
 ADP-ribosylation factor-like 4C
 173560
 0.03
chr7_150635354_150635936 0.53 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 17349
 0.15
chr14_99720519_99720759 0.47 AL109767.1
8646
 0.22
chr10_98301601_98301752 0.47 TLL2
 tolloid-like 2
 28008
 0.18
chr22_19463070_19463221 0.44 UFD1L
 ubiquitin fusion degradation 1 like (yeast)
 3309
 0.13
chr12_112779348_112779499 0.44 HECTD4
 HECT domain containing E3 ubiquitin protein ligase 4
 40473
 0.14
chr11_20135030_20135181 0.42 NAV2-AS1
 NAV2 antisense RNA 1
 7073
 0.24
chrX_107068310_107068461 0.42 MID2
 midline 2
 600
 0.75
chr1_180549413_180549564 0.41 ENSG00000266683
 .
 34520
 0.16
chr3_9445704_9445855 0.41 SETD5-AS1
 SETD5 antisense RNA 1
 5516
 0.16
chr15_81248608_81248759 0.41 KIAA1199
 KIAA1199
 22916
 0.14
chr5_142562188_142562394 0.40 ARHGAP26-IT1
 ARHGAP26 intronic transcript 1 (non-protein coding)
 9774
 0.25
chr6_3159984_3160135 0.39 TUBB2A
 tubulin, beta 2A class IIa
 2299
 0.23
chr1_92019254_92019429 0.39 CDC7
 cell division cycle 7
 52646
 0.17
chr5_96000301_96000453 0.39 CAST
 calpastatin
 1620
 0.38
chr15_50648645_50649024 0.39 ENSG00000244879
 .
 166
 0.9
chr16_50219117_50219379 0.38 PAPD5
 PAP associated domain containing 5
 31469
 0.14
chr12_95196881_95197032 0.37 ENSG00000208038
 .
 31218
 0.23
chr2_23603358_23603509 0.37 KLHL29
 kelch-like family member 29
 4655
 0.35
chr19_31557220_31557371 0.37 AC020952.1
 Uncharacterized protein
 83067
 0.11
chr14_75672848_75673038 0.36 ENSG00000252013
 .
 4071
 0.19
chr10_96161826_96161977 0.36 TBC1D12
 TBC1 domain family, member 12
 360
 0.9
chr1_181121299_181121450 0.36 IER5
 immediate early response 5
 63736
 0.13
chr20_62042443_62042594 0.36 RP11-358D14.2
36886
 0.09
chr5_140998829_140999245 0.36 DIAPH1
 diaphanous-related formin 1
 415
 0.66
chr3_160940381_160941002 0.35 NMD3
 NMD3 ribosome export adaptor
 1344
 0.59
chr1_172644665_172644877 0.35 FASLG
 Fas ligand (TNF superfamily, member 6)
 16613
 0.25
chr16_67618812_67618963 0.35 CTCF
 CCCTC-binding factor (zinc finger protein)
 22577
 0.08
chr11_117917434_117917585 0.35 ENSG00000272075
 .
 20443
 0.14
chr22_20226344_20226543 0.35 RTN4R
 reticulon 4 receptor
 4764
 0.15
chrX_106928490_106928775 0.35 TSC22D3
 TSC22 domain family, member 3
 30999
 0.18
chr5_39231622_39231809 0.34 FYB
 FYN binding protein
 12007
 0.28
chr20_57231559_57231809 0.34 STX16
 syntaxin 16
 4621
 0.19
chr10_130706677_130706967 0.34 MGMT
 O-6-methylguanine-DNA methyltransferase
 558626
 0.0
chr15_60871759_60871981 0.33 RORA
 RAR-related orphan receptor A
 12870
 0.21
chr2_99954705_99955291 0.33 EIF5B
 eukaryotic translation initiation factor 5B
 1182
 0.4
chr2_119188712_119188863 0.33 INSIG2
 insulin induced gene 2
 342737
 0.01
chr15_48251538_48251689 0.33 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 161556
 0.03
chr6_112306754_112307040 0.33 WISP3
 WNT1 inducible signaling pathway protein 3
 68378
 0.11
chr6_119227091_119227242 0.32 ASF1A
 anti-silencing function 1A histone chaperone
 11782
 0.19
chr18_60458887_60459075 0.32 AC015989.1
 Uncharacterized protein
 32442
 0.17
chr3_122048704_122048855 0.32 CSTA
 cystatin A (stefin A)
 4670
 0.19
chr8_71124474_71124716 0.32 NCOA2
 nuclear receptor coactivator 2
 33015
 0.21
chr4_99563113_99563379 0.32 TSPAN5
 tetraspanin 5
 15540
 0.22
chr4_110483700_110484182 0.32 CCDC109B
 coiled-coil domain containing 109B
 1795
 0.42
chr17_47440332_47440604 0.32 ZNF652
 zinc finger protein 652
 633
 0.61
chr9_20320271_20320422 0.31 ENSG00000221744
 .
 25344
 0.21
chr10_33425697_33425907 0.31 ENSG00000263576
 .
 38238
 0.16
chr14_52795656_52796058 0.31 PTGER2
 prostaglandin E receptor 2 (subtype EP2), 53kDa
 14744
 0.25
chr12_74884186_74884337 0.31 ATXN7L3B
 ataxin 7-like 3B
 47290
 0.17
chr14_53158829_53159146 0.31 ERO1L
 ERO1-like (S. cerevisiae)
 3260
 0.21
chr2_62806762_62807072 0.30 TMEM17
 transmembrane protein 17
 73441
 0.1
chr1_12291292_12291653 0.30 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 1348
 0.41
chr6_139492633_139492784 0.30 HECA
 headcase homolog (Drosophila)
 36459
 0.17
chr2_202297300_202297558 0.30 TRAK2
 trafficking protein, kinesin binding 2
 848
 0.59
chr9_20490846_20490997 0.30 ENSG00000264941
 .
 11419
 0.23
chr8_144097895_144098282 0.30 LY6E
 lymphocyte antigen 6 complex, locus E
 1311
 0.42
chr10_29772721_29772872 0.29 SVIL
 supervillin
 12651
 0.23
chr17_62180290_62180441 0.29 ERN1
 endoplasmic reticulum to nucleus signaling 1
 27120
 0.14
chr7_73265347_73265568 0.29 WBSCR27
 Williams Beuren syndrome chromosome region 27
 8592
 0.15
chr5_36949315_36949466 0.29 NIPBL
 Nipped-B homolog (Drosophila)
 72498
 0.13
chr4_10107887_10108195 0.29 ENSG00000223086
 .
 9467
 0.16
chr14_65380506_65380744 0.29 CHURC1
 churchill domain containing 1
 454
 0.38
chr17_63031973_63032289 0.29 RP11-583F2.5
15896
 0.16
chr7_156809109_156809289 0.29 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 5700
 0.18
chr20_37165542_37165693 0.29 ENSG00000263473
 .
 20411
 0.13
chr8_25033335_25033486 0.29 ENSG00000241811
 .
 5825
 0.25
chr16_4674083_4674234 0.29 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
 633
 0.59
chr3_183544116_183544267 0.28 MAP6D1
 MAP6 domain containing 1
 809
 0.53
chr5_140934914_140935065 0.28 CTD-2024I7.13
2889
 0.17
chr15_83733229_83733380 0.28 BTBD1
 BTB (POZ) domain containing 1
 2599
 0.17
chr20_56969877_56970028 0.28 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
 5583
 0.26
chr1_112491159_112491310 0.28 KCND3
 potassium voltage-gated channel, Shal-related subfamily, member 3
 34184
 0.17
chr9_33431365_33431516 0.28 AQP3
 aquaporin 3 (Gill blood group)
 16169
 0.14
chr12_105956829_105956980 0.28 C12orf75
 chromosome 12 open reading frame 75
 232258
 0.02
chr1_193428730_193429035 0.28 ENSG00000252241
 .
 272192
 0.01
chr2_228735932_228736236 0.28 DAW1
 dynein assembly factor with WDR repeat domains 1
 239
 0.94
chr6_139482795_139483056 0.28 HECA
 headcase homolog (Drosophila)
 26676
 0.21
chr12_64798932_64799366 0.28 XPOT
 exportin, tRNA
 323
 0.88
chr13_53027549_53027700 0.28 CKAP2
 cytoskeleton associated protein 2
 1940
 0.3
chr8_120219756_120219907 0.28 MAL2
 mal, T-cell differentiation protein 2 (gene/pseudogene)
 779
 0.76
chr1_172149548_172149911 0.28 DNM3OS
 DNM3 opposite strand/antisense RNA
 35795
 0.15
chr3_119015914_119016065 0.28 ARHGAP31
 Rho GTPase activating protein 31
 2769
 0.24
chr6_35149420_35149571 0.27 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 32695
 0.14
chr4_88929574_88929774 0.27 PKD2
 polycystic kidney disease 2 (autosomal dominant)
 854
 0.61
chr5_170763650_170763947 0.27 ENSG00000265740
 .
 22323
 0.14
chr5_95294789_95295005 0.27 ELL2
 elongation factor, RNA polymerase II, 2
 2655
 0.26
chr3_156478754_156479058 0.27 LEKR1
 leucine, glutamate and lysine rich 1
 65183
 0.12
chr14_66404533_66404789 0.27 CTD-2014B16.3
 Uncharacterized protein
 66580
 0.13
chr18_46918320_46918471 0.27 DYM
 dymeclin
 13376
 0.18
chr13_26475136_26475287 0.27 AL138815.2
 Uncharacterized protein
 22532
 0.17
chr22_36232750_36232901 0.27 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 3440
 0.35
chr5_40511051_40511202 0.26 ENSG00000199552
 .
 143939
 0.04
chr15_42352123_42352335 0.26 PLA2G4E
 phospholipase A2, group IVE
 8841
 0.16
chr22_32046621_32046810 0.26 PISD
 phosphatidylserine decarboxylase
 11451
 0.2
chr2_148804260_148804811 0.26 ORC4
 origin recognition complex, subunit 4
 25388
 0.19
chr22_40654247_40654479 0.26 TNRC6B
 trinucleotide repeat containing 6B
 6644
 0.26
chr16_70097897_70098048 0.26 PDXDC2P
1707
 0.31
chr1_100889654_100889805 0.26 ENSG00000216067
 .
 45398
 0.13
chr6_73135306_73135457 0.26 RIMS1
 regulating synaptic membrane exocytosis 1
 58949
 0.16
chr21_19188629_19188846 0.26 C21orf91
 chromosome 21 open reading frame 91
 2599
 0.3
chr1_116185862_116186059 0.26 VANGL1
 VANGL planar cell polarity protein 1
 710
 0.71
chr4_39364717_39364868 0.26 RFC1
 replication factor C (activator 1) 1, 145kDa
 3177
 0.21
chr8_87524414_87524565 0.26 RMDN1
 regulator of microtubule dynamics 1
 2078
 0.28
chrX_16661091_16661259 0.26 S100G
 S100 calcium binding protein G
 7106
 0.18
chr8_91783068_91783219 0.26 NECAB1
 N-terminal EF-hand calcium binding protein 1
 20635
 0.19
chr9_5531438_5531729 0.26 PDCD1LG2
 programmed cell death 1 ligand 2
 21013
 0.22
chr11_2966895_2967126 0.25 PHLDA2
 pleckstrin homology-like domain, family A, member 2
 16325
 0.11
chr15_34873680_34873831 0.25 GOLGA8B
 golgin A8 family, member B
 2016
 0.29
chr14_69238852_69239003 0.25 ZFP36L1
 ZFP36 ring finger protein-like 1
 19033
 0.19
chr9_118131626_118131777 0.25 DEC1
 deleted in esophageal cancer 1
 227604
 0.02
chr1_10569828_10570301 0.25 PEX14
 peroxisomal biogenesis factor 14
 35025
 0.11
chr14_76605047_76605198 0.25 GPATCH2L
 G patch domain containing 2-like
 13140
 0.26
chr5_150644691_150644842 0.25 GM2A
 GM2 ganglioside activator
 5406
 0.2
chr2_31440406_31440557 0.25 CAPN14
 calpain 14
 70
 0.97
chr18_33647690_33647852 0.25 RPRD1A
 regulation of nuclear pre-mRNA domain containing 1A
 232
 0.94
chr6_4804997_4805148 0.25 CDYL
 chromodomain protein, Y-like
 28403
 0.2
chr17_39874084_39874250 0.25 ENSG00000201920
 .
 239
 0.85
chr2_143918611_143918880 0.25 RP11-190J23.1
10996
 0.25
chr11_82617435_82617696 0.25 C11orf82
 chromosome 11 open reading frame 82
 2735
 0.27
chr13_99867467_99867663 0.25 ENSG00000201793
 .
 9603
 0.19
chr3_142296047_142296384 0.25 ATR
 ataxia telangiectasia and Rad3 related
 1453
 0.37
chr3_132137362_132137693 0.24 DNAJC13
 DnaJ (Hsp40) homolog, subfamily C, member 13
 1157
 0.6
chr11_14378772_14379652 0.24 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 819
 0.73
chr8_61918765_61918944 0.24 CLVS1
 clavesin 1
 50863
 0.18
chr17_41668721_41668956 0.24 ETV4
 ets variant 4
 11850
 0.16
chr8_110987376_110987527 0.24 KCNV1
 potassium channel, subfamily V, member 1
 492
 0.75
chr9_100744268_100744520 0.24 ANP32B
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
 1249
 0.39
chr1_223084470_223084621 0.24 ENSG00000239054
 .
 744
 0.72
chr6_48037013_48037164 0.24 PTCHD4
 patched domain containing 4
 663
 0.83
chr16_85369002_85369321 0.24 RP11-680G10.1
 Uncharacterized protein
 21908
 0.2
chr6_37665777_37665940 0.24 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 92
 0.98
chr12_104329327_104329478 0.24 ENSG00000265072
 .
 5199
 0.15
chr5_54605298_54605894 0.24 SKIV2L2
 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
 1767
 0.29
chr14_63940495_63940646 0.24 ENSG00000252463
 .
 3922
 0.18
chr1_171702173_171702324 0.24 VAMP4
 vesicle-associated membrane protein 4
 8954
 0.19
chr12_50580729_50580880 0.24 RP3-405J10.3
4342
 0.14
chr17_48618789_48619185 0.24 ENSG00000250286
 .
 2872
 0.13
chr3_15687980_15688217 0.24 BTD
 biotinidase
 44622
 0.11
chr17_64644644_64644795 0.24 ENSG00000251698
 .
 9332
 0.19
chr4_38092282_38092433 0.24 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 44865
 0.19
chr5_55911226_55911525 0.24 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 9316
 0.26
chr12_51015541_51015966 0.24 ENSG00000207136
 .
 11303
 0.21
chr5_141503692_141503877 0.23 NDFIP1
 Nedd4 family interacting protein 1
 15714
 0.23
chr7_23036448_23036599 0.23 FAM126A
 family with sequence similarity 126, member A
 17170
 0.24
chr2_228275751_228276175 0.23 TM4SF20
 transmembrane 4 L six family member 20
 29252
 0.16
chr3_45209403_45209586 0.23 CDCP1
 CUB domain containing protein 1
 21580
 0.2
chr18_2588153_2588403 0.23 NDC80
 NDC80 kinetochore complex component
 10430
 0.14
chr3_30664719_30665032 0.23 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 16782
 0.27
chr7_99005041_99005202 0.23 BUD31
 BUD31 homolog (S. cerevisiae)
 1143
 0.26
chr1_10555616_10555775 0.23 PEX14
 peroxisomal biogenesis factor 14
 20656
 0.12
chr2_238787700_238787851 0.23 ENSG00000263723
 .
 9228
 0.2
chr2_101171486_101171889 0.23 ENSG00000266005
 .
 825
 0.59
chr15_89170331_89170558 0.23 AEN
 apoptosis enhancing nuclease
 5843
 0.16
chr8_128412696_128412847 0.23 POU5F1B
 POU class 5 homeobox 1B
 13764
 0.24
chr4_146102106_146102613 0.23 OTUD4
 OTU domain containing 4
 1046
 0.59
chr10_105525632_105525787 0.23 SH3PXD2A
 SH3 and PX domains 2A
 35346
 0.17
chr9_32524416_32524567 0.23 DDX58
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
 1702
 0.32
chr11_14375636_14375787 0.23 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 335
 0.93
chr21_46496959_46497110 0.23 ADARB1
 adenosine deaminase, RNA-specific, B1
 2519
 0.22
chr14_103270514_103270708 0.23 ENSG00000238853
 .
 14683
 0.17
chr2_10025449_10025600 0.23 TAF1B
 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
 9397
 0.23
chr3_152888395_152888546 0.23 RAP2B
 RAP2B, member of RAS oncogene family
 8441
 0.21
chr4_36396689_36396840 0.23 RP11-431M7.2
2732
 0.4
chr1_175139081_175139232 0.23 KIAA0040
 KIAA0040
 22734
 0.22
chr1_235406790_235406941 0.23 ARID4B
 AT rich interactive domain 4B (RBP1-like)
 29634
 0.16
chr7_29605198_29605734 0.23 PRR15
 proline rich 15
 400
 0.84
chr14_92973076_92973375 0.23 RIN3
 Ras and Rab interactor 3
 6893
 0.29
chr6_106590141_106590398 0.23 RP1-134E15.3
42254
 0.16
chr2_99095585_99095903 0.22 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 34331
 0.18
chr7_45962099_45962436 0.22 IGFBP3
 insulin-like growth factor binding protein 3
 794
 0.65
chr1_3619930_3620081 0.22 TP73
 tumor protein p73
 5383
 0.13
chr5_64919668_64919819 0.22 TRIM23
 tripartite motif containing 23
 380
 0.59
chr1_24971768_24971919 0.22 SRRM1
 serine/arginine repetitive matrix 1
 1793
 0.32
chr3_16522193_16522470 0.22 RFTN1
 raftlin, lipid raft linker 1
 2041
 0.43
chr7_4819835_4819986 0.22 AP5Z1
 adaptor-related protein complex 5, zeta 1 subunit
 4646
 0.17
chr2_145081239_145081390 0.22 GTDC1
 glycosyltransferase-like domain containing 1
 3877
 0.36
chr10_71981169_71981370 0.22 PPA1
 pyrophosphatase (inorganic) 1
 11891
 0.2
chr7_100477718_100477869 0.22 SRRT
 serrate RNA effector molecule homolog (Arabidopsis)
 4782
 0.1
chr10_35050362_35050513 0.22 PARD3
 par-3 family cell polarity regulator
 53812
 0.14
chr19_39686992_39687200 0.22 NCCRP1
 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
 505
 0.69
chr4_39638786_39639138 0.22 SMIM14
 small integral membrane protein 14
 1551
 0.38
chr8_58807157_58807308 0.22 FAM110B
 family with sequence similarity 110, member B
 99881
 0.09
chr11_34948593_34948744 0.22 PDHX
 pyruvate dehydrogenase complex, component X
 10480
 0.19
chr16_27185640_27185898 0.22 KDM8
 lysine (K)-specific demethylase 8
 29038
 0.17
chr13_74644571_74644841 0.22 KLF12
 Kruppel-like factor 12
 63688
 0.15
chr11_96059054_96059205 0.22 ENSG00000266192
 .
 15473
 0.19
chr2_235401803_235401954 0.22 ARL4C
 ADP-ribosylation factor-like 4C
 3366
 0.4
chr16_3865090_3865241 0.22 CREBBP
 CREB binding protein
 34297
 0.17
chr17_17640963_17641296 0.22 RAI1-AS1
 RAI1 antisense RNA 1
 33006
 0.11
chr5_114504885_114505107 0.21 TRIM36
 tripartite motif containing 36
 610
 0.73
chr3_128601669_128601820 0.21 ACAD9
 acyl-CoA dehydrogenase family, member 9
 3272
 0.23
chr5_133389529_133390012 0.21 VDAC1
 voltage-dependent anion channel 1
 48946
 0.13
chr10_131583616_131583767 0.21 EBF3
 early B-cell factor 3
 56744
 0.14
chr10_63603062_63603213 0.21 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 57922
 0.14
chr2_197084220_197084574 0.21 ENSG00000239161
 .
 4351
 0.23
chr3_71686752_71686903 0.21 FOXP1
 forkhead box P1
 53687
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.1 GO:0051284 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.2 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.2 GO:0048242 epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742) histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.0 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.2 GO:0043576 regulation of respiratory gaseous exchange(GO:0043576)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.0 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0010819 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.0 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of apoptotic process involved in morphogenesis(GO:1902337) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) regulation of apoptotic process involved in development(GO:1904748)
0.0 0.0 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0002385 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.3 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.3 GO:0097306 cellular response to alcohol(GO:0097306)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0010510 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832) negative regulation of striated muscle cell differentiation(GO:0051154)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.0 GO:0032205 negative regulation of telomere maintenance(GO:0032205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis