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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for MXI1_MYC_MYCN

Z-value: 2.52

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Transcription factors associated with MXI1_MYC_MYCN

Gene Symbol	Gene ID	Gene Info
MXI1 Ensembl NCBI GeneCards UniProt	ENSG00000119950.16	MAX interactor 1, dimerization protein
MYC Ensembl NCBI GeneCards UniProt	ENSG00000136997.10	MYC proto-oncogene, bHLH transcription factor
MYCN Ensembl NCBI GeneCards UniProt	ENSG00000134323.10	MYCN proto-oncogene, bHLH transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_111908092_111908243	MXI1	59196	0.120560	0.73	2.5e-02	Click!
chr10_111983854_111984005	MXI1	1822	0.390042	-0.69	4.0e-02	Click!
chr10_111928036_111928187	MXI1	39252	0.161712	-0.69	4.1e-02	Click!
chr10_111874268_111874419	MXI1	93020	0.069919	0.68	4.4e-02	Click!
chr10_111918134_111918285	MXI1	49154	0.140549	-0.65	6.1e-02	Click!
chr8_128773308_128773464	MYC	24909	0.212649	0.88	1.9e-03	Click!
chr8_128773097_128773252	MYC	24697	0.213410	0.79	1.2e-02	Click!
chr8_128772034_128772185	MYC	23632	0.217223	0.77	1.5e-02	Click!
chr8_128680662_128680813	MYC	66943	0.131110	-0.69	3.8e-02	Click!
chr8_128746114_128746265	MYC	1491	0.528450	-0.69	3.9e-02	Click!
chr2_16079818_16079969	MYCN	793	0.522809	0.53	1.4e-01	Click!
chr2_16080483_16080772	MYCN	59	0.929615	-0.47	2.0e-01	Click!
chr2_16080025_16080176	MYCN	586	0.626007	-0.13	7.4e-01	Click!
chr2_16079611_16079811	MYCN	975	0.453049	0.07	8.6e-01	Click!
chr2_16080238_16080427	MYCN	354	0.771359	0.07	8.7e-01	Click!

Activity of the MXI1_MYC_MYCN motif across conditions

Conditions sorted by the z-value of the MXI1_MYC_MYCN motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_29167036_29167187	1.32	CTB-134H23.3		48345	0.11
chr12_123752997_123753556	1.30	CDK2AP1	cyclin-dependent kinase 2 associated protein 1	445	0.72
chr4_106080082_106080344	1.19	TET2	tet methylcytosine dioxygenase 2	11599	0.21
chr17_48718114_48718630	1.17	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	6154	0.13
chr15_90379706_90380333	1.11	ENSG00000264966	.	13934	0.11
chr1_33849901_33850220	1.10	PHC2	polyhomeotic homolog 2 (Drosophila)	8866	0.16
chr5_14264414_14265476	1.05	TRIO	trio Rho guanine nucleotide exchange factor	26141	0.27
chr10_134373100_134373292	1.02	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	21553	0.2
chr13_114280008_114280159	0.96	ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	32418	0.15
chr14_65121936_65122087	0.96	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	48809	0.12
chr4_26220381_26220779	0.96	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	53649	0.18
chr7_1601786_1602053	0.88	TMEM184A	transmembrane protein 184A	1462	0.35
chr3_129316608_129316897	0.86	ENSG00000239437	.	6560	0.17
chr1_234856307_234857026	0.85	IRF2BP2	interferon regulatory factor 2 binding protein 2	111395	0.06
chr13_114883288_114883480	0.85	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	9089	0.22
chr21_46727783_46727934	0.84	ENSG00000215447	.	19891	0.16
chr18_72936572_72937273	0.84	TSHZ1	teashirt zinc finger homeobox 1	3909	0.29
chr8_49341467_49342503	0.84	ENSG00000252710	.	121395	0.06
chr9_125108943_125109186	0.84	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	23760	0.11
chr13_114882746_114882897	0.82	RASA3-IT1	RASA3 intronic transcript 1 (non-protein coding)	8526	0.22
chr7_157092599_157092750	0.82	ENSG00000266453	.	5813	0.26
chr17_76238005_76238295	0.81	TMEM235	transmembrane protein 235	10028	0.13
chr9_132338939_132339359	0.81	RP11-492E3.2		1461	0.33
chr13_114280229_114280380	0.80	ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	32197	0.15
chr3_113345260_113345597	0.80	ENSG00000241529	.	6123	0.18
chr11_118850990_118851222	0.80	FOXR1	forkhead box R1	1617	0.16
chr20_31063505_31064006	0.79	C20orf112	chromosome 20 open reading frame 112	7519	0.19
chr2_232186868_232187222	0.78	ENSG00000263641	.	40374	0.13
chr17_76312953_76313854	0.78	SOCS3	suppressor of cytokine signaling 3	42752	0.1
chr6_170365530_170365681	0.77	RP11-302L19.1		112136	0.06
chr16_87617546_87617733	0.77	RP11-482M8.3		18157	0.18
chr9_115625123_115625465	0.77	RP11-408O19.5		22144	0.17
chr1_235104740_235105149	0.77	ENSG00000239690	.	65011	0.12
chr12_124992848_124993269	0.74	NCOR2	nuclear receptor corepressor 2	9782	0.31
chr17_25886952_25887281	0.73	KSR1	kinase suppressor of ras 1	22831	0.19
chr11_65601039_65601190	0.73	SNX32	sorting nexin 32	2	0.95
chr16_3900112_3900331	0.72	CREBBP	CREB binding protein	29900	0.18
chr2_206595838_206596065	0.72	AC007362.3		32726	0.2
chr2_64867824_64868062	0.71	SERTAD2	SERTA domain containing 2	13104	0.23
chr9_93880537_93881196	0.71	AUH	AU RNA binding protein/enoyl-CoA hydratase	243311	0.02
chr20_23065783_23065982	0.71	CD93	CD93 molecule	1095	0.49
chr11_67896240_67896572	0.70	CTD-2655K5.1		859	0.55
chr12_109080507_109080751	0.70	CORO1C	coronin, actin binding protein, 1C	9549	0.15
chr19_41328238_41328415	0.70	EGLN2	egl-9 family hypoxia-inducible factor 2	15178	0.12
chr1_11902208_11902500	0.70	NPPA-AS1	NPPA antisense RNA 1	1280	0.3
chr9_94660876_94661276	0.69	ROR2	receptor tyrosine kinase-like orphan receptor 2	50086	0.18
chr14_69516631_69516869	0.69	ACTN1-AS1	ACTN1 antisense RNA 1	69992	0.1
chr1_9127158_9127594	0.68	SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	2228	0.26
chr11_62165677_62166025	0.68	CTD-2531D15.5		5007	0.13
chr17_32563089_32563474	0.68	CCL2	chemokine (C-C motif) ligand 2	19023	0.12
chr7_73497247_73497589	0.67	LIMK1	LIM domain kinase 1	155	0.96
chr2_8675294_8675837	0.67	AC011747.7		140331	0.05
chr16_78402274_78402828	0.67	RP11-190D6.2		127436	0.05
chr17_78801110_78801319	0.67	RP11-28G8.1		21782	0.2
chr18_20837841_20838532	0.67	RP11-17J14.2		2132	0.4
chr13_32059321_32059637	0.66	RXFP2	relaxin/insulin-like family peptide receptor 2	254195	0.02
chr19_28959653_28959994	0.64	ENSG00000238514	.	462087	0.01
chr2_45240825_45241114	0.64	SIX2	SIX homeobox 2	4400	0.31
chr16_20864584_20864864	0.64	DCUN1D3	DCN1, defective in cullin neddylation 1, domain containing 3	15578	0.15
chr14_91281521_91281794	0.64	TTC7B	tetratricopeptide repeat domain 7B	1104	0.63
chr7_508753_509105	0.64	PDGFA	platelet-derived growth factor alpha polypeptide	49216	0.14
chr7_47615850_47616225	0.64	TNS3	tensin 3	5192	0.32
chr1_173159483_173159962	0.64	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	14975	0.26
chr4_26273396_26273688	0.64	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	687	0.82
chr2_65084720_65084888	0.64	ENSG00000199964	.	23513	0.15
chr8_96023333_96023599	0.64	NDUFAF6	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	13748	0.16
chr3_186648798_186649082	0.63	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	64	0.98
chr12_113478639_113478925	0.63	DTX1	deltex homolog 1 (Drosophila)	16713	0.15
chr22_46392610_46393183	0.63	WNT7B	wingless-type MMTV integration site family, member 7B	19887	0.12
chr20_45753039_45753288	0.63	ENSG00000264901	.	42446	0.18
chr6_158506907_158507345	0.63	SYNJ2	synaptojanin 2	8414	0.21
chr6_6696175_6696468	0.62	LY86-AS1	LY86 antisense RNA 1	73317	0.12
chr6_52416826_52417180	0.62	TRAM2	translocation associated membrane protein 2	24710	0.22
chr16_57513119_57513312	0.62	DOK4	docking protein 4	502	0.72
chr3_127484247_127484497	0.62	MGLL	monoglyceride lipase	18479	0.22
chr19_2524704_2524855	0.61	ENSG00000252962	.	21640	0.14
chr5_158448429_158448934	0.61	CTD-2363C16.2		35867	0.17
chr10_77408049_77408416	0.61	RP11-310J24.3		5998	0.28
chr7_47612540_47612691	0.61	TNS3	tensin 3	8614	0.29
chr9_137301054_137301205	0.61	RXRA	retinoid X receptor, alpha	2701	0.34
chr1_41467777_41468071	0.61	CTPS1	CTP synthase 1	19091	0.19
chr20_17631217_17631686	0.60	RRBP1	ribosome binding protein 1	9701	0.21
chr4_86747445_86747851	0.60	ARHGAP24	Rho GTPase activating protein 24	1250	0.59
chr2_37751330_37751623	0.60	AC006369.2		75803	0.1
chr21_35917035_35917316	0.60	RCAN1	regulator of calcineurin 1	15302	0.2
chr7_75592437_75593112	0.60	POR	P450 (cytochrome) oxidoreductase	4387	0.19
chr8_17080916_17081067	0.60	CNOT7	CCR4-NOT transcription complex, subunit 7	11378	0.21
chr19_2187224_2187437	0.59	DOT1L	DOT1-like histone H3K79 methyltransferase	23146	0.09
chr1_45466698_45467046	0.59	HECTD3	HECT domain containing E3 ubiquitin protein ligase 3	7351	0.14
chr2_11838549_11838700	0.59	AC106875.1		17037	0.12
chr5_151062800_151063025	0.59	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	1879	0.27
chr16_85110105_85110256	0.59	KIAA0513	KIAA0513	886	0.64
chr8_6419329_6419534	0.58	ANGPT2	angiopoietin 2	1134	0.61
chr15_90608689_90609006	0.58	ZNF710	zinc finger protein 710	2399	0.22
chr15_67055010_67055873	0.57	SMAD6	SMAD family member 6	51406	0.15
chr14_61789232_61789447	0.57	PRKCH	protein kinase C, eta	43	0.71
chr9_127052151_127052520	0.57	NEK6	NIMA-related kinase 6	1915	0.33
chr16_21552235_21552606	0.57	ENSG00000265462	.	34964	0.11
chr17_72508456_72508770	0.57	CD300LB	CD300 molecule-like family member b	18992	0.13
chr2_120996591_120996972	0.57	RALB	v-ral simian leukemia viral oncogene homolog B	859	0.59
chr9_139220671_139220944	0.57	GPSM1	G-protein signaling modulator 1	1125	0.31
chr15_75348526_75348677	0.57	PPCDC	phosphopantothenoylcysteine decarboxylase	12985	0.15
chr9_116756307_116756581	0.57	AMBP	alpha-1-microglobulin/bikunin precursor	80805	0.09
chr7_158533073_158533405	0.57	ESYT2	extended synaptotagmin-like protein 2	3669	0.29
chr14_78070314_78070649	0.57	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	6817	0.2
chr5_14351305_14351522	0.57	TRIO	trio Rho guanine nucleotide exchange factor	60327	0.16
chr2_11836925_11837076	0.56	AC106875.1		15413	0.12
chr10_127798713_127799096	0.56	ENSG00000222740	.	35247	0.2
chr17_3598834_3599357	0.56	P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5	232	0.86
chr7_20447658_20447906	0.56	ENSG00000200753	.	30828	0.2
chr12_52596781_52596986	0.56	KRT80	keratin 80	11099	0.12
chr17_6851867_6852055	0.56	RP11-530N7.3		30318	0.08
chr9_137394449_137394849	0.56	RXRA	retinoid X receptor, alpha	96221	0.07
chr2_42982517_42982668	0.55	OXER1	oxoeicosanoid (OXE) receptor 1	8809	0.22
chr3_185531728_185531979	0.55	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	6996	0.24
chr16_88220538_88220993	0.55	BANP	BTG3 associated nuclear protein	217141	0.02
chr17_74526963_74527181	0.55	CYGB	cytoglobin	1075	0.29
chr2_145263610_145263985	0.55	ZEB2	zinc finger E-box binding homeobox 2	11318	0.24
chr15_66914114_66914568	0.55	RP11-321F6.1	HCG2003567; Uncharacterized protein	39813	0.12
chr18_332034_332193	0.55	THOC1	THO complex 1	64086	0.12
chr14_105147633_105147901	0.55	ENSG00000265291	.	3681	0.16
chr11_121593109_121593338	0.55	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	132095	0.05
chr7_47783586_47783886	0.55	LINC00525	long intergenic non-protein coding RNA 525	17338	0.22
chr16_85597214_85597712	0.54	GSE1	Gse1 coiled-coil protein	47552	0.14
chr15_90365308_90365459	0.54	ANPEP	alanyl (membrane) aminopeptidase	6750	0.13
chr7_47493733_47494035	0.54	TNS3	tensin 3	1055	0.7
chr10_12392435_12392590	0.54	CAMK1D	calcium/calmodulin-dependent protein kinase ID	780	0.64
chr21_47716320_47716676	0.54	YBEY	ybeY metallopeptidase (putative)	9939	0.11
chr13_32740029_32740180	0.54	FRY	furry homolog (Drosophila)	98701	0.07
chr7_20259929_20260378	0.54	MACC1	metastasis associated in colon cancer 1	3126	0.32
chr3_127480240_127480489	0.54	MGLL	monoglyceride lipase	22487	0.21
chr1_1290112_1290528	0.54	MXRA8	matrix-remodelling associated 8	3595	0.08
chr15_67316146_67316685	0.54	SMAD3	SMAD family member 3	39686	0.2
chr12_2450783_2451189	0.53	CACNA1C-IT3	CACNA1C intronic transcript 3 (non-protein coding)	72044	0.11
chr2_8143997_8144330	0.53	ENSG00000221255	.	427191	0.01
chr3_5095854_5096064	0.53	ENSG00000207283	.	32005	0.16
chr14_69365004_69365155	0.53	ACTN1	actinin, alpha 1	8220	0.24
chr7_5518471_5518623	0.53	ENSG00000238394	.	6479	0.13
chr10_79972594_79972997	0.53	ENSG00000201393	.	154469	0.04
chr22_19468388_19468693	0.53	CDC45	cell division cycle 45	1079	0.32
chr20_25207702_25207867	0.53	AL035252.1	HCG2018895; Uncharacterized protein	414	0.81
chr10_81171650_81171847	0.53	RP11-342M3.5		29664	0.16
chr19_19096304_19096549	0.53	AC004447.2		5276	0.13
chr18_22878825_22879093	0.53	CTD-2006O16.2		3131	0.37
chr5_53877579_53877803	0.53	SNX18	sorting nexin 18	64098	0.14
chr19_344757_345175	0.53	MIER2	mesoderm induction early response 1, family member 2	173	0.94
chr16_88999792_89000220	0.53	RP11-830F9.7		4158	0.14
chr8_142130774_142131146	0.52	DENND3	DENN/MADD domain containing 3	3583	0.25
chr22_44555974_44556161	0.52	PARVG	parvin, gamma	12769	0.26
chr17_78431617_78431991	0.52	NPTX1	neuronal pentraxin I	18600	0.15
chr13_96162429_96162593	0.52	CLDN10-AS1	CLDN10 antisense RNA 1	23653	0.21
chr15_101499460_101499680	0.52	LRRK1	leucine-rich repeat kinase 1	40020	0.15
chr5_264432_264583	0.52	CTD-2083E4.6		7124	0.14
chr12_13330961_13331112	0.52	EMP1	epithelial membrane protein 1	18614	0.22
chr3_129278537_129278688	0.52	PLXND1	plexin D1	1287	0.38
chr7_81400181_81400399	0.52	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	536	0.87
chr19_10415862_10416105	0.52	ZGLP1	zinc finger, GATA-like protein 1	4476	0.08
chr17_8383287_8383438	0.52	NDEL1	nudE neurodevelopment protein 1-like 1	29263	0.12
chr7_101688884_101689543	0.52	CTA-357J21.1		12910	0.24
chr3_194089316_194089467	0.52	LRRC15	leucine rich repeat containing 15	1069	0.5
chr15_50549728_50549936	0.52	HDC	histidine decarboxylase	5794	0.16
chr3_190251314_190251476	0.51	IL1RAP	interleukin 1 receptor accessory protein	19504	0.24
chr1_226234793_226235057	0.51	H3F3A	H3 histone, family 3A	14627	0.16
chr19_7570726_7571036	0.51	CTD-2207O23.12	Uncharacterized protein	1087	0.31
chr19_45428791_45429158	0.51	APOC1P1	apolipoprotein C-I pseudogene 1	1259	0.23
chr3_53184032_53184571	0.51	PRKCD	protein kinase C, delta	5724	0.19
chr13_21608420_21608654	0.51	ENSG00000201821	.	4269	0.18
chr20_48889352_48889575	0.51	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	82087	0.08
chr1_230144508_230144659	0.51	ENSG00000211525	.	40414	0.18
chr19_50180650_50180909	0.51	PRMT1	protein arginine methyltransferase 1	20	0.93
chr15_81604400_81605338	0.51	STARD5	StAR-related lipid transfer (START) domain containing 5	11597	0.18
chr1_150025814_150026054	0.51	VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)	13435	0.16
chr11_44011003_44011154	0.51	C11orf96	chromosome 11 open reading frame 96	47023	0.11
chr11_72896529_72896905	0.51	RP11-800A3.2		30241	0.13
chr7_5673752_5673979	0.51	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	39548	0.12
chr12_32698572_32698774	0.51	FGD4	FYVE, RhoGEF and PH domain containing 4	11415	0.26
chr20_58514182_58514656	0.50	PPP1R3D	protein phosphatase 1, regulatory subunit 3D	933	0.39
chr13_22244150_22244530	0.50	FGF9	fibroblast growth factor 9	1182	0.58
chr8_144427255_144427725	0.50	TOP1MT	topoisomerase (DNA) I, mitochondrial	336	0.78
chr19_46378887_46379170	0.50	IRF2BP1	interferon regulatory factor 2 binding protein 1	10348	0.1
chr12_49626134_49626329	0.50	TUBA1C	tubulin, alpha 1c	4522	0.14
chr11_126211364_126211625	0.50	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	14061	0.13
chr12_20557654_20557988	0.50	RP11-284H19.1		34625	0.2
chr22_46402793_46403252	0.50	WNT7B	wingless-type MMTV integration site family, member 7B	30013	0.1
chr5_17225431_17225585	0.50	BASP1	brain abundant, membrane attached signal protein 1	7839	0.18
chr3_122803125_122803484	0.50	PDIA5	protein disulfide isomerase family A, member 5	17109	0.23
chr20_43331812_43332067	0.50	RP11-445H22.3		7202	0.14
chr11_60544654_60544805	0.50	MS4A10	membrane-spanning 4-domains, subfamily A, member 10	8092	0.13
chr11_1146453_1147024	0.50	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	4842	0.22
chr6_169946443_169946594	0.50	WDR27	WD repeat domain 27	114270	0.06
chr4_3323825_3323976	0.50	RGS12	regulator of G-protein signaling 12	6105	0.26
chr8_99413835_99413986	0.50	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	25340	0.18
chr16_11726272_11726564	0.50	LITAF	lipopolysaccharide-induced TNF factor	3352	0.24
chr1_183040294_183040646	0.49	LAMC1	laminin, gamma 1 (formerly LAMB2)	25209	0.19
chr7_372645_372959	0.49	AC187652.1	Protein LOC100996433	69884	0.12
chr3_48596905_48597280	0.49	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	195	0.88
chr7_92369983_92370216	0.49	ENSG00000206763	.	38971	0.18
chr2_235866357_235866729	0.49	SH3BP4	SH3-domain binding protein 4	5823	0.35
chr3_29376763_29376914	0.49	ENSG00000216169	.	34074	0.18
chr2_176945225_176945564	0.49	EVX2	even-skipped homeobox 2	3247	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MXI1_MYC_MYCN

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.3	2.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.3	0.8	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.3	1.1	GO:0007028	cytoplasm organization(GO:0007028)
0.3	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	1.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.7	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.2	0.7	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.2	0.7	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.2	0.9	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	0.6	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.2	0.4	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2	0.8	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.6	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2	0.7	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	1.9	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.2	0.5	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.2	0.8	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.2	0.5	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.5	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	0.5	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.6	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.4	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.4	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.4	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.6	GO:0018101	protein citrullination(GO:0018101)
0.1	0.4	GO:0032898	neurotrophin production(GO:0032898)
0.1	0.4	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.7	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	0.8	GO:0016265	obsolete death(GO:0016265)
0.1	0.5	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.3	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.5	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.7	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.1	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.1	0.7	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	1.0	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.3	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.4	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.4	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.2	GO:0022601	menstrual cycle phase(GO:0022601)
0.1	0.3	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.4	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.3	GO:0010193	response to ozone(GO:0010193)
0.1	0.2	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.4	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.3	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.1	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1	0.3	GO:0090103	cochlea morphogenesis(GO:0090103)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.6	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.1	0.5	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.5	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0060525	prostate glandular acinus development(GO:0060525)
0.1	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	1.0	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.3	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.5	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1	0.3	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.2	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.2	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.2	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.4	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.3	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.2	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	1.6	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.1	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.1	0.3	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.1	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.9	GO:0034605	cellular response to heat(GO:0034605)
0.1	0.3	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1	0.2	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.6	GO:0043277	apoptotic cell clearance(GO:0043277)
0.1	0.3	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.3	GO:0007549	dosage compensation(GO:0007549)
0.1	0.2	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.8	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.1	GO:0043954	cellular component maintenance(GO:0043954)
0.1	0.2	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.1	0.7	GO:0050926	regulation of positive chemotaxis(GO:0050926)
0.1	0.4	GO:0002070	epithelial cell maturation(GO:0002070)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.1	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.1	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.4	GO:0048854	brain morphogenesis(GO:0048854)
0.1	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.5	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.3	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	0.4	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.3	GO:0015732	prostaglandin transport(GO:0015732)
0.1	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.4	GO:0034505	tooth mineralization(GO:0034505)
0.1	0.2	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.2	GO:0033622	integrin activation(GO:0033622)
0.1	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.6	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.2	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0045188	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.2	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0014034	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.3	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.5	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.2	GO:1904478	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.2	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.3	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.5	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0060992	response to fungicide(GO:0060992)
0.0	0.2	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0	0.2	GO:0042228	interleukin-8 biosynthetic process(GO:0042228)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0051503	purine nucleotide transport(GO:0015865) adenine nucleotide transport(GO:0051503)
0.0	0.6	GO:0042116	macrophage activation(GO:0042116)
0.0	0.0	GO:0030185	nitric oxide transport(GO:0030185)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.9	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.3	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.2	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.5	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.1	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0032352	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.6	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.2	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.5	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.2	GO:0030501	positive regulation of bone mineralization(GO:0030501) positive regulation of biomineral tissue development(GO:0070169)
0.0	0.2	GO:0048486	parasympathetic nervous system development(GO:0048486)
0.0	0.4	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0052803	histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:0003417	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.3	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.0	GO:0042482	positive regulation of odontogenesis(GO:0042482)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.1	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.4	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.1	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.1	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.1	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.1	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.3	GO:0016180	snRNA processing(GO:0016180)
0.0	0.2	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.3	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0031223	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0	0.2	GO:0001508	action potential(GO:0001508)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.2	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0003307	regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.0	GO:0051299	centrosome separation(GO:0051299)
0.0	0.2	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.5	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.4	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.0	GO:0046049	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0019363	pyridine nucleotide biosynthetic process(GO:0019363)
0.0	0.1	GO:0051570	negative regulation of histone methylation(GO:0031061) regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0006907	pinocytosis(GO:0006907)
0.0	0.4	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.2	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.0	GO:0021602	glossopharyngeal nerve development(GO:0021563) cranial nerve morphogenesis(GO:0021602) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0043691	reverse cholesterol transport(GO:0043691)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.5	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.2	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.8	GO:0006826	iron ion transport(GO:0006826)
0.0	0.1	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.0	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.5	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.0	GO:0032370	positive regulation of lipid transport(GO:0032370)
0.0	0.0	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0032108	negative regulation of response to food(GO:0032096) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.4	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.2	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0043243	positive regulation of protein complex disassembly(GO:0043243)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.3	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.0	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0051923	sulfation(GO:0051923)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0060214	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0	0.1	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0072665	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.0	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.0	0.1	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.0	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.3	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.3	GO:0001740	Barr body(GO:0001740)
0.1	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.3	GO:0045298	tubulin complex(GO:0045298)
0.1	0.5	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.2	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.5	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	0.4	GO:0030673	axolemma(GO:0030673)
0.1	0.1	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.2	GO:0043205	fibril(GO:0043205)
0.1	0.4	GO:0031143	pseudopodium(GO:0031143)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.6	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.3	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.3	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	3.4	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.5	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.6	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0070069	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) cytochrome complex(GO:0070069)
0.0	0.9	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.4	GO:0043204	perikaryon(GO:0043204)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.0	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.8	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.2	0.7	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	0.7	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.2	0.7	GO:0001849	complement component C1q binding(GO:0001849)
0.2	0.7	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	1.0	GO:0048406	nerve growth factor binding(GO:0048406)
0.2	0.6	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	1.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	0.5	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2	0.7	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	0.7	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.2	1.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.5	GO:0003680	AT DNA binding(GO:0003680)
0.2	1.4	GO:0017166	vinculin binding(GO:0017166)
0.1	0.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.6	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.5	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.4	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.8	GO:0034595	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.8	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.4	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	1.0	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1	0.9	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.5	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	1.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.1	0.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.3	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	1.0	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.4	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.4	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1	0.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.4	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.1	0.3	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.2	GO:0046980	tapasin binding(GO:0046980)
0.1	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.1	0.6	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.5	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.1	1.2	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.3	GO:0032052	bile acid binding(GO:0032052)
0.1	0.8	GO:0019894	kinesin binding(GO:0019894)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.5	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.2	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.5	GO:0005112	Notch binding(GO:0005112)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	1.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.3	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.6	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.6	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.3	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.5	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.6	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	3.2	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0032142	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	1.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.3	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:0016918	retinal binding(GO:0016918)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.3	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.5	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0048038	quinone binding(GO:0048038)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.4	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	1.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0019203	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0010851	cyclase regulator activity(GO:0010851)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	2.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	2.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	1.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	ST ADRENERGIC	Adrenergic Pathway
0.0	0.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	3.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.3	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	3.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID EPHA FWDPATHWAY	EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.2	0.5	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.2	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.6	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	0.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	1.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.6	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.2	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.1	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	1.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.6	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.0	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription

Results for MXI1_MYC_MYCN

Z-value: 2.52

Motif logo

Transcription factors associated with MXI1_MYC_MYCN

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MXI1_MYC_MYCN motif across conditions

Conditions sorted by the z-value of the MXI1_MYC_MYCN motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MXI1_MYC_MYCN

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: