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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for MYB

Z-value: 1.83

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Transcription factors associated with MYB

Gene Symbol	Gene ID	Gene Info
MYB Ensembl NCBI GeneCards UniProt	ENSG00000118513.14	MYB proto-oncogene, transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_135469965_135470116	MYB	32413	0.150398	0.93	2.6e-04	Click!
chr6_135506749_135506941	MYB	311	0.894962	0.85	3.7e-03	Click!
chr6_135507007_135507309	MYB	2	0.977830	0.82	7.4e-03	Click!
chr6_135469313_135469464	MYB	33065	0.148915	0.70	3.6e-02	Click!
chr6_135501797_135502026	MYB	542	0.774600	0.68	4.2e-02	Click!

Activity of the MYB motif across conditions

Conditions sorted by the z-value of the MYB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_16478953_16479699	0.58	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	6562	0.16
chr16_89044159_89044400	0.57	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	667	0.66
chr20_24930029_24930180	0.54	CST7	cystatin F (leukocystatin)	238	0.94
chr2_44318364_44318661	0.52	ENSG00000252599	.	63522	0.1
chr18_74827758_74827973	0.51	MBP	myelin basic protein	10648	0.29
chr14_65510786_65511085	0.47	ENSG00000266531	.	471	0.75
chr6_159461301_159461469	0.42	TAGAP	T-cell activation RhoGTPase activating protein	4665	0.21
chr3_155271866_155272126	0.42	PLCH1-AS2	PLCH1 antisense RNA 2	68404	0.11
chr9_71161800_71162163	0.41	TMEM252	transmembrane protein 252	6198	0.29
chr19_1104140_1104299	0.41	GPX4	glutathione peroxidase 4	147	0.92
chrX_2815646_2815988	0.40	ARSD-AS1	ARSD antisense RNA 1	7128	0.17
chr2_149403538_149403753	0.39	EPC2	enhancer of polycomb homolog 2 (Drosophila)	656	0.82
chr8_135844862_135845072	0.39	ENSG00000199153	.	27779	0.21
chr16_81483531_81483723	0.38	CMIP	c-Maf inducing protein	4852	0.28
chr11_65869163_65869474	0.37	PACS1	phosphofurin acidic cluster sorting protein 1	1084	0.36
chr1_182360343_182360566	0.37	GLUL	glutamate-ammonia ligase	85	0.97
chr9_34125688_34125839	0.36	DCAF12	DDB1 and CUL4 associated factor 12	38	0.97
chr6_52529046_52529271	0.36	RP1-152L7.5		914	0.6
chr7_105711154_105711314	0.36	SYPL1	synaptophysin-like 1	27074	0.22
chr20_48467849_48468000	0.35	ENSG00000252123	.	23395	0.14
chr13_46753070_46753349	0.35	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	3250	0.21
chr1_47044937_47045228	0.35	MKNK1	MAP kinase interacting serine/threonine kinase 1	6150	0.16
chr1_15930197_15930348	0.34	RP4-680D5.2		151	0.92
chr5_75747200_75747364	0.34	IQGAP2	IQ motif containing GTPase activating protein 2	47033	0.17
chr9_78714748_78715100	0.34	PCSK5	proprotein convertase subtilisin/kexin type 5	4031	0.37
chr12_4262653_4262869	0.34	CCND2	cyclin D2	120177	0.05
chr11_122586005_122586216	0.34	ENSG00000239079	.	10909	0.24
chr11_85867980_85868160	0.34	ENSG00000200877	.	3801	0.28
chr1_148555913_148556064	0.34	NBPF15	neuroblastoma breakpoint family, member 15	4855	0.29
chr11_57529390_57529570	0.34	CTNND1	catenin (cadherin-associated protein), delta 1	190	0.92
chr22_30664164_30664336	0.33	OSM	oncostatin M	1421	0.25
chr3_50607030_50607235	0.33	HEMK1	HemK methyltransferase family member 1	208	0.89
chr9_124015547_124015716	0.33	GSN	gelsolin	14707	0.14
chr7_50354428_50354714	0.33	IKZF1	IKAROS family zinc finger 1 (Ikaros)	6253	0.31
chr10_111970132_111970295	0.33	MXI1	MAX interactor 1, dimerization protein	224	0.93
chr19_18218266_18218571	0.32	IL12RB1	interleukin 12 receptor, beta 1	8664	0.13
chr4_55685405_55685705	0.32	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	161470	0.04
chr1_227139840_227139991	0.32	ADCK3	aarF domain containing kinase 3	11920	0.22
chr12_47756185_47756391	0.32	ENSG00000264906	.	1764	0.4
chr17_72004567_72004816	0.32	RPL38	ribosomal protein L38	195030	0.02
chr21_43722272_43722538	0.32	ENSG00000216197	.	1950	0.27
chr7_149449989_149450274	0.32	ZNF467	zinc finger protein 467	20177	0.18
chr17_7145935_7146086	0.32	GABARAP	GABA(A) receptor-associated protein	79	0.9
chr1_200996525_200996676	0.31	KIF21B	kinesin family member 21B	3772	0.22
chr15_52049077_52049228	0.31	CTD-2308G16.1		4470	0.16
chr16_71322796_71323005	0.31	CMTR2	cap methyltransferase 2	252	0.92
chr4_40201848_40202166	0.31	RHOH	ras homolog family member H	43	0.98
chr15_70755158_70755354	0.31	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	239364	0.02
chr6_119683416_119683658	0.31	MAN1A1	mannosidase, alpha, class 1A, member 1	12611	0.25
chr1_92981375_92981732	0.31	GFI1	growth factor independent 1 transcription repressor	29120	0.22
chr1_207490924_207491154	0.30	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	3814	0.32
chrX_153361761_153361912	0.30	MECP2	methyl CpG binding protein 2 (Rett syndrome)	600	0.67
chr13_32437208_32437458	0.30	EEF1DP3	eukaryotic translation elongation factor 1 delta pseudogene 3	89384	0.09
chr15_50404362_50404513	0.30	ATP8B4	ATPase, class I, type 8B, member 4	2264	0.36
chr14_23763578_23763917	0.30	RP11-124D2.7		66	0.9
chr10_25013530_25013681	0.30	ARHGAP21	Rho GTPase activating protein 21	1008	0.67
chr13_36871748_36871899	0.30	CCDC169	coiled-coil domain containing 169	63	0.46
chr13_24817805_24817956	0.30	SPATA13	spermatogenesis associated 13	7952	0.19
chr2_30467105_30467275	0.30	LBH	limb bud and heart development	12144	0.24
chr15_99601132_99601283	0.30	SYNM	synemin, intermediate filament protein	37213	0.12
chr11_67186435_67186586	0.30	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	2142	0.11
chr8_134257961_134258179	0.29	WISP1-OT1	WISP1 overlapping transcript 1 (non-protein coding)	16771	0.22
chrX_39865999_39866213	0.29	BCOR	BCL6 corepressor	56084	0.17
chr1_29224735_29224890	0.29	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	4559	0.19
chr2_112761594_112761846	0.29	MERTK	c-mer proto-oncogene tyrosine kinase	15270	0.22
chr10_11203289_11203522	0.29	CELF2	CUGBP, Elav-like family member 2	3588	0.26
chr10_70481589_70481793	0.29	CCAR1	cell division cycle and apoptosis regulator 1	682	0.59
chr10_31609488_31609880	0.29	ENSG00000237036	.	308	0.56
chr10_11219483_11219897	0.29	RP3-323N1.2		6351	0.23
chr7_142999680_142999831	0.29	ENSG00000240322	.	4146	0.11
chr15_101817244_101817395	0.29	VIMP	VCP-interacting membrane protein	173	0.93
chr10_11376391_11376681	0.29	CELF2-AS1	CELF2 antisense RNA 1	14689	0.28
chr11_43965052_43965302	0.29	C11orf96	chromosome 11 open reading frame 96	1122	0.46
chr17_45148805_45148956	0.29	ENSG00000263650	.	29689	0.12
chr9_34983449_34984034	0.29	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	5897	0.15
chr4_42722794_42722988	0.29	RP11-109E24.2		63378	0.13
chr1_229294714_229294972	0.29	RP5-1061H20.5		68466	0.1
chr11_45000738_45000916	0.29	TP53I11	tumor protein p53 inducible protein 11	28219	0.22
chr12_107715976_107716127	0.28	BTBD11	BTB (POZ) domain containing 11	1686	0.47
chr2_3104176_3104426	0.28	ENSG00000238722	.	24757	0.24
chr1_39282420_39282754	0.28	RRAGC	Ras-related GTP binding C	42908	0.12
chr1_205673701_205673897	0.28	AC119673.1		8698	0.15
chr2_202899288_202899439	0.28	FZD7	frizzled family receptor 7	53	0.97
chr7_50347648_50348106	0.28	IKZF1	IKAROS family zinc finger 1 (Ikaros)	440	0.9
chr2_238888231_238888382	0.28	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	6569	0.22
chr9_137820655_137820823	0.28	FCN1	ficolin (collagen/fibrinogen domain containing) 1	10930	0.14
chr5_173958937_173959224	0.28	MSX2	msh homeobox 2	192456	0.03
chr22_24822413_24822699	0.28	ADORA2A	adenosine A2a receptor	974	0.56
chr4_172734246_172734409	0.28	GALNTL6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6	327	0.95
chr19_3360665_3360877	0.28	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	1090	0.51
chr1_27683765_27684109	0.28	MAP3K6	mitogen-activated protein kinase kinase kinase 6	975	0.41
chr2_172961333_172961519	0.28	DLX2	distal-less homeobox 2	6202	0.22
chr16_85640793_85640944	0.28	GSE1	Gse1 coiled-coil protein	4147	0.25
chr13_46754157_46754322	0.28	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	2220	0.26
chr6_39307371_39307522	0.28	KCNK16	potassium channel, subfamily K, member 16	16702	0.21
chr3_193560043_193560289	0.28	ENSG00000243991	.	101656	0.07
chr7_37704424_37704590	0.28	GPR141	G protein-coupled receptor 141	18893	0.22
chr9_136241871_136242236	0.28	SURF4	surfeit 4	861	0.28
chr15_74919459_74919649	0.28	CLK3	CDC-like kinase 3	225	0.91
chr10_116285157_116285366	0.28	ABLIM1	actin binding LIM protein 1	1333	0.56
chr17_75316778_75316929	0.27	SEPT9	septin 9	458	0.85
chr12_104940585_104940756	0.27	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	41956	0.17
chr10_101416049_101416204	0.27	RP11-483F11.7		2464	0.21
chr5_176937147_176937410	0.27	DOK3	docking protein 3	105	0.93
chr7_6475884_6476035	0.27	DAGLB	diacylglycerol lipase, beta	11604	0.16
chr1_228271631_228271782	0.27	ARF1	ADP-ribosylation factor 1	855	0.48
chr8_48647056_48647250	0.27	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	4495	0.21
chr16_88765948_88766142	0.27	RNF166	ring finger protein 166	69	0.92
chr6_4778966_4779117	0.27	CDYL	chromodomain protein, Y-like	2372	0.32
chr7_149647376_149647563	0.27	ATP6V0E2-AS1	ATP6V0E2 antisense RNA 1	69770	0.1
chr8_27196599_27196773	0.27	PTK2B	protein tyrosine kinase 2 beta	12346	0.21
chr17_10024109_10024420	0.27	GAS7	growth arrest-specific 7	6394	0.22
chr7_37430269_37430515	0.27	ENSG00000200113	.	28839	0.16
chr2_219258625_219258977	0.27	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	4260	0.1
chr2_234258431_234258582	0.27	RP11-400N9.1		3556	0.18
chr1_25258373_25258525	0.27	RUNX3	runt-related transcription factor 3	2081	0.36
chr18_74828060_74828346	0.27	MBP	myelin basic protein	10986	0.29
chr10_102087421_102087574	0.27	PKD2L1	polycystic kidney disease 2-like 1	2232	0.21
chr11_128483614_128483860	0.26	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	26284	0.19
chr10_119303450_119303630	0.26	EMX2	empty spiracles homeobox 2	1031	0.41
chr4_153605170_153605347	0.26	TMEM154	transmembrane protein 154	3941	0.25
chr19_11680938_11681089	0.26	ACP5	acid phosphatase 5, tartrate resistant	7329	0.11
chr1_17607126_17607277	0.26	ENSG00000266634	.	2817	0.22
chr7_37713043_37713194	0.26	GPR141	G protein-coupled receptor 141	10282	0.23
chrX_13770949_13771164	0.26	OFD1	oral-facial-digital syndrome 1	18192	0.17
chr13_111175572_111175723	0.26	COL4A2-AS1	COL4A2 antisense RNA 1	15121	0.2
chr15_90606107_90606258	0.26	ZNF710	zinc finger protein 710	5064	0.16
chr10_116092441_116092592	0.26	AFAP1L2	actin filament associated protein 1-like 2	71723	0.1
chr10_126299645_126299796	0.26	FAM53B-AS1	FAM53B antisense RNA 1	92474	0.07
chr1_157914955_157915130	0.26	RP11-451O13.1		20187	0.2
chr22_32035521_32035693	0.26	PISD	phosphatidylserine decarboxylase	1176	0.51
chr4_140899620_140899786	0.26	MAML3	mastermind-like 3 (Drosophila)	87582	0.09
chr5_169721674_169721825	0.26	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	3482	0.28
chr7_77096125_77096301	0.26	ENSG00000238453	.	43108	0.15
chr17_27942794_27942945	0.26	CORO6	coronin 6	2266	0.13
chr12_6753133_6753285	0.26	ACRBP	acrosin binding protein	3350	0.1
chr10_105669481_105669746	0.26	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	7814	0.18
chr8_144655209_144655539	0.26	MROH6	maestro heat-like repeat family member 6	233	0.51
chr15_41184746_41184897	0.26	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	1807	0.22
chr10_4169858_4170276	0.26	KLF6	Kruppel-like factor 6	342594	0.01
chr8_144660678_144660898	0.26	NAPRT1	nicotinate phosphoribosyltransferase domain containing 1	5	0.91
chr14_21250121_21250386	0.26	RNASE6	ribonuclease, RNase A family, k6	1043	0.34
chr3_107820810_107821187	0.26	CD47	CD47 molecule	11126	0.3
chr1_249132941_249133092	0.26	ZNF672	zinc finger protein 672	11	0.97
chr7_102066247_102066509	0.26	ORAI2	ORAI calcium release-activated calcium modulator 2	7175	0.09
chr2_213966916_213967088	0.26	IKZF2	IKAROS family zinc finger 2 (Helios)	46351	0.18
chr17_37788030_37788408	0.25	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	3468	0.14
chr12_65369994_65370192	0.25	ENSG00000221564	.	37290	0.18
chr8_96225080_96225231	0.25	C8orf37	chromosome 8 open reading frame 37	56274	0.13
chr3_37941057_37941273	0.25	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	37500	0.13
chr12_27093857_27094008	0.25	FGFR1OP2	FGFR1 oncogene partner 2	2499	0.21
chr2_98708440_98708797	0.25	VWA3B	von Willebrand factor A domain containing 3B	4919	0.31
chr11_112832866_112833087	0.25	NCAM1	neural cell adhesion molecule 1	774	0.48
chr12_105032244_105032461	0.25	ENSG00000264295	.	46941	0.16
chr10_6634389_6634749	0.25	PRKCQ	protein kinase C, theta	12306	0.31
chr10_16858653_16859078	0.25	RSU1	Ras suppressor protein 1	517	0.86
chr15_90568095_90568246	0.25	ENSG00000265871	.	18183	0.14
chr5_102201797_102201948	0.25	PAM	peptidylglycine alpha-amidating monooxygenase	52	0.99
chr2_7078035_7078186	0.25	RNF144A	ring finger protein 144A	4936	0.23
chr5_135469095_135469294	0.25	SMAD5	SMAD family member 5	152	0.94
chr16_85110269_85110512	0.25	KIAA0513	KIAA0513	676	0.74
chr3_71495817_71496096	0.25	ENSG00000221264	.	95284	0.08
chr11_61809937_61810088	0.25	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	74559	0.06
chr9_116113235_116113415	0.25	BSPRY	B-box and SPRY domain containing	1504	0.3
chr8_29242547_29242792	0.25	RP4-676L2.1		31982	0.15
chr6_6718533_6718684	0.25	LY86-AS1	LY86 antisense RNA 1	95604	0.09
chr2_54226182_54226333	0.25	ACYP2	acylphosphatase 2, muscle type	28012	0.17
chr6_21603925_21604076	0.25	SOX4	SRY (sex determining region Y)-box 4	9929	0.33
chr2_97628467_97628722	0.25	ENSG00000252845	.	6042	0.16
chr6_15361722_15361995	0.25	ENSG00000201519	.	37155	0.16
chr3_46171138_46171427	0.25	CCR3	chemokine (C-C motif) receptor 3	33814	0.18
chr2_223580693_223580844	0.25	ENSG00000238852	.	18049	0.21
chr11_129764974_129765125	0.25	NFRKB	nuclear factor related to kappaB binding protein	403	0.88
chr14_90186897_90187134	0.25	ENSG00000200312	.	8160	0.23
chr9_80531962_80532113	0.25	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	94122	0.09
chr2_159826290_159826457	0.25	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	1190	0.52
chr10_121242342_121242493	0.25	RGS10	regulator of G-protein signaling 10	44572	0.15
chr12_96466863_96467052	0.25	ENSG00000266889	.	29070	0.14
chr11_95098962_95099113	0.25	ENSG00000201204	.	107501	0.07
chr20_30815578_30815729	0.25	ENSG00000221667	.	9945	0.14
chr2_85767177_85767896	0.25	MAT2A	methionine adenosyltransferase II, alpha	771	0.45
chr10_73610452_73610603	0.25	PSAP	prosaposin	555	0.77
chr1_150750336_150750487	0.24	CTSS	cathepsin S	11978	0.13
chr11_118057344_118057495	0.24	SCN2B	sodium channel, voltage-gated, type II, beta subunit	10031	0.14
chr3_187636177_187636831	0.24	BCL6	B-cell CLL/lymphoma 6	172989	0.03
chr13_111833278_111833429	0.24	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	3932	0.25
chr17_42786397_42786612	0.24	DBF4B	DBF4 homolog B (S. cerevisiae)	453	0.74
chr7_127053042_127053319	0.24	ZNF800	zinc finger protein 800	18798	0.23
chr14_39307887_39308107	0.24	ENSG00000199285	.	148488	0.04
chr19_50083532_50083683	0.24	NOSIP	nitric oxide synthase interacting protein	196	0.58
chr12_56101174_56101338	0.24	ITGA7	integrin, alpha 7	229	0.84
chr17_2272405_2272617	0.24	SGSM2	small G protein signaling modulator 2	5655	0.11
chr11_74975561_74975768	0.24	CTD-2562J17.9		331	0.84
chr11_72498251_72498402	0.24	STARD10	StAR-related lipid transfer (START) domain containing 10	1314	0.31
chr12_105075895_105076476	0.24	ENSG00000264295	.	90774	0.08
chr13_52135052_52135280	0.24	ENSG00000252141	.	4382	0.15
chr12_66585334_66585492	0.24	IRAK3	interleukin-1 receptor-associated kinase 3	2376	0.25
chr11_121449666_121449817	0.24	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	2194	0.46
chr11_2320673_2321045	0.24	C11orf21	chromosome 11 open reading frame 21	2284	0.19
chr7_108165461_108166027	0.24	PNPLA8	patatin-like phospholipase domain containing 8	771	0.69

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.5	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.3	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.2	GO:0001711	endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1	0.4	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.1	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.1	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.2	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.3	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.2	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.2	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.3	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.5	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.5	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.3	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.3	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.2	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0002883	hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0052556	positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.5	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.3	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.0	0.2	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0006266	DNA ligation(GO:0006266)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.4	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0021779	oligodendrocyte cell fate commitment(GO:0021779)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.5	GO:0009084	glutamine family amino acid biosynthetic process(GO:0009084)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.3	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.1	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.1	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.0	GO:0032847	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.0	0.2	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.7	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.2	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.5	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.6	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.8	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.1	GO:0032769	negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.0	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.1	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0043300	regulation of leukocyte degranulation(GO:0043300)
0.0	0.1	GO:0060479	lung cell differentiation(GO:0060479)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0051136	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0046033	AMP metabolic process(GO:0046033)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.0	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0002921	negative regulation of humoral immune response(GO:0002921)
0.0	0.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.2	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.1	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.4	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0045588	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.2	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.2	GO:0044036	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0098534	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0043299	leukocyte degranulation(GO:0043299)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0032329	L-serine transport(GO:0015825) serine transport(GO:0032329)
0.0	0.1	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.0	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.0	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0048525	negative regulation of viral process(GO:0048525) negative regulation of viral life cycle(GO:1903901)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0009081	branched-chain amino acid metabolic process(GO:0009081)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:1904358	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.1	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.2	GO:0010043	response to zinc ion(GO:0010043)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0006298	mismatch repair(GO:0006298)
0.0	0.1	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.2	GO:0003407	neural retina development(GO:0003407)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.2	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0042119	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0042424	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:2000272	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170) negative regulation of receptor activity(GO:2000272)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.0	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.0	GO:0001773	myeloid dendritic cell activation(GO:0001773)
0.0	0.0	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.4	GO:0031345	negative regulation of cell projection organization(GO:0031345)
0.0	0.0	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0032747	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0044126	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) negative regulation of growth of symbiont in host(GO:0044130) modulation of growth of symbiont involved in interaction with host(GO:0044144) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0014888	striated muscle adaptation(GO:0014888)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.0	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0045414	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-8 biosynthetic process(GO:0045414) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0	0.2	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.0	GO:0051181	cofactor transport(GO:0051181)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.1	GO:0046051	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.7	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0	0.2	GO:0007435	salivary gland morphogenesis(GO:0007435)
0.0	0.1	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.3	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.2	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.4	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0032153	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.0	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.0	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0016589	NURF complex(GO:0016589)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.4	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.4	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.5	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.5	GO:0019864	IgG binding(GO:0019864)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	0.2	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0008443	phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.2	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.2	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.3	GO:0016408	C-acyltransferase activity(GO:0016408)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.4	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.3	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	1.7	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.0	0.1	GO:0043176	amine binding(GO:0043176)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.6	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.3	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID CDC42 PATHWAY	CDC42 signaling events
0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.8	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.2	PID EPO PATHWAY	EPO signaling pathway
0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.5	PID LKB1 PATHWAY	LKB1 signaling events
0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	PID FOXO PATHWAY	FoxO family signaling
0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.3	PID ATR PATHWAY	ATR signaling pathway
0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME TRIF MEDIATED TLR3 SIGNALING	Genes involved in TRIF mediated TLR3 signaling
0.0	0.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME S PHASE	Genes involved in S Phase
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.0	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME NEURONAL SYSTEM	Genes involved in Neuronal System
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins

Results for MYB

Z-value: 1.83

Motif logo

Transcription factors associated with MYB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the MYB motif across conditions

Conditions sorted by the z-value of the MYB motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: