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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MYF6

Z-value: 0.80

Motif logo

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Transcription factors associated with MYF6

Gene Symbol Gene ID Gene Info
ENSG00000111046.3 MYF6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
MYF6chr12_81101667_811018184650.8354080.608.5e-02Click!
MYF6chr12_81102661_8110285014780.4364730.412.8e-01Click!
MYF6chr12_81101957_811021117570.6861230.265.0e-01Click!
MYF6chr12_81102321_8110251211390.5294720.157.0e-01Click!
MYF6chr12_81097094_8109724541080.2464280.078.5e-01Click!

Activity of the MYF6 motif across conditions

Conditions sorted by the z-value of the MYF6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_42186030_42186402 0.26 SGK2
serum/glucocorticoid regulated kinase 2
1392
0.36
chr12_120427135_120427403 0.23 CCDC64
coiled-coil domain containing 64
404
0.87
chr2_27305313_27305464 0.22 EMILIN1
elastin microfibril interfacer 1
1075
0.26
chr6_6636840_6637139 0.21 LY86-AS1
LY86 antisense RNA 1
13985
0.26
chr3_171547801_171548005 0.20 TMEM212
transmembrane protein 212
13236
0.18
chr15_90583479_90583717 0.20 ZNF710
zinc finger protein 710
27648
0.12
chr3_107148782_107148933 0.20 CCDC54
coiled-coil domain containing 54
52669
0.15
chr5_95108981_95109222 0.20 RHOBTB3
Rho-related BTB domain containing 3
5257
0.19
chr18_374955_375106 0.19 RP11-720L2.2

49386
0.15
chr2_74783730_74784343 0.18 LOXL3
lysyl oxidase-like 3
1219
0.25
chr17_43278136_43278287 0.18 CTD-2020K17.1

19488
0.09
chr2_71291273_71291652 0.18 AC007040.8

411
0.73
chr5_158655488_158655639 0.18 ENSG00000252458
.
1639
0.34
chr10_7124084_7124395 0.18 SFMBT2
Scm-like with four mbt domains 2
326468
0.01
chr1_212844814_212845399 0.18 ENSG00000207491
.
20500
0.14
chr4_100780978_100781132 0.17 LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
34478
0.16
chr6_51167860_51168049 0.17 ENSG00000212532
.
161534
0.04
chr9_37993909_37994194 0.17 ENSG00000251745
.
57286
0.12
chr16_48653717_48653876 0.17 N4BP1
NEDD4 binding protein 1
9676
0.19
chrX_19915221_19915598 0.17 SH3KBP1
SH3-domain kinase binding protein 1
9690
0.25
chr12_654579_654730 0.17 B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
2355
0.27
chr16_2556960_2557241 0.17 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
6771
0.06
chr17_40670908_40671198 0.17 ENSG00000265611
.
4847
0.09
chr6_146755943_146756197 0.16 ENSG00000222971
.
94514
0.08
chr7_73240850_73241001 0.16 CLDN4
claudin 4
1149
0.42
chr7_26590451_26590692 0.16 KIAA0087
KIAA0087
12164
0.27
chr1_233217531_233217682 0.16 PCNXL2
pecanex-like 2 (Drosophila)
23342
0.26
chr9_21119427_21119782 0.16 IFNW1
interferon, omega 1
22540
0.12
chr1_25439261_25439439 0.16 ENSG00000264371
.
89356
0.07
chr20_4930731_4930882 0.16 SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
50513
0.12
chr22_46427472_46427760 0.16 RP6-109B7.5

21357
0.1
chr13_111175044_111175195 0.16 COL4A2-AS1
COL4A2 antisense RNA 1
14593
0.2
chr1_110306049_110306352 0.16 EPS8L3
EPS8-like 3
326
0.84
chr10_35776302_35776593 0.16 GJD4
gap junction protein, delta 4, 40.1kDa
117891
0.05
chr8_91657659_91657810 0.15 TMEM64
transmembrane protein 64
6
0.96
chr11_113847463_113847737 0.15 HTR3A
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
622
0.76
chr15_69652696_69652882 0.15 ENSG00000252972
.
7135
0.13
chr10_73620300_73620451 0.15 PSAP
prosaposin
9249
0.2
chr3_197878509_197878660 0.15 AC073135.3

41507
0.14
chr20_48889044_48889195 0.15 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
81743
0.08
chr5_149867249_149867416 0.15 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
1475
0.4
chr2_145440654_145440805 0.15 ZEB2
zinc finger E-box binding homeobox 2
162108
0.04
chr9_35042246_35042534 0.15 C9orf131
chromosome 9 open reading frame 131
180
0.73
chr11_77213533_77213871 0.14 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
28022
0.15
chr7_6474034_6474265 0.14 DAGLB
diacylglycerol lipase, beta
13414
0.16
chr13_95254337_95254566 0.14 GPR180
G protein-coupled receptor 180
294
0.91
chr1_182113646_182113797 0.14 ZNF648
zinc finger protein 648
82874
0.1
chr1_21399249_21399400 0.14 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
16377
0.24
chrX_70390205_70390391 0.14 NLGN3
neuroligin 3
25586
0.1
chr22_18210286_18210437 0.14 ENSG00000264757
.
36664
0.14
chr3_4520289_4520508 0.14 SUMF1
sulfatase modifying factor 1
11433
0.2
chr4_144435798_144435959 0.14 SMARCA5-AS1
SMARCA5 antisense RNA 1
90
0.96
chr9_136038241_136038401 0.14 GBGT1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
961
0.35
chr11_69457785_69457945 0.14 CCND1
cyclin D1
1891
0.38
chr20_30666848_30667078 0.14 HCK
hemopoietic cell kinase
26899
0.1
chr8_122140841_122140992 0.14 ENSG00000221644
.
58216
0.14
chr7_27615419_27615570 0.13 HIBADH
3-hydroxyisobutyrate dehydrogenase
71881
0.11
chr15_40628103_40628665 0.13 C15orf52
chromosome 15 open reading frame 52
1857
0.16
chr4_139335299_139335467 0.13 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
171880
0.04
chr15_101709991_101710273 0.13 CHSY1
chondroitin sulfate synthase 1
82005
0.08
chr5_139727515_139728049 0.13 HBEGF
heparin-binding EGF-like growth factor
1566
0.26
chr6_106957352_106957633 0.13 AIM1
absent in melanoma 1
2238
0.32
chr7_47641377_47641730 0.13 TNS3
tensin 3
19397
0.24
chr20_32551295_32551527 0.13 RALY
RALY heterogeneous nuclear ribonucleoprotein
30041
0.18
chr14_58765318_58765585 0.13 ARID4A
AT rich interactive domain 4A (RBP1-like)
145
0.84
chr10_89875342_89875493 0.13 ENSG00000200891
.
120965
0.06
chr10_82355785_82355994 0.13 SH2D4B
SH2 domain containing 4B
55314
0.14
chr1_172792534_172792808 0.13 FASLG
Fas ligand (TNF superfamily, member 6)
164513
0.04
chr7_26344110_26344302 0.13 SNX10
sorting nexin 10
11532
0.23
chr8_37761152_37761429 0.13 RAB11FIP1
RAB11 family interacting protein 1 (class I)
4305
0.16
chr20_30641676_30641832 0.13 HCK
hemopoietic cell kinase
1690
0.25
chr5_77793836_77794265 0.13 LHFPL2
lipoma HMGIC fusion partner-like 2
50924
0.17
chr7_95237066_95237395 0.13 AC002451.3

1878
0.37
chr17_40990067_40990218 0.13 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
4629
0.09
chr20_1356162_1356422 0.13 RP11-314N13.3

14026
0.14
chr4_74864141_74864430 0.13 CXCL5
chemokine (C-X-C motif) ligand 5
211
0.91
chr19_16263728_16264013 0.13 HSH2D
hematopoietic SH2 domain containing
9324
0.12
chr8_19743814_19744105 0.13 LPL
lipoprotein lipase
15269
0.24
chr17_18933418_18933712 0.13 GRAP
GRB2-related adaptor protein
12233
0.11
chr6_41744687_41744838 0.13 FRS3
fibroblast growth factor receptor substrate 3
1157
0.31
chr17_76908326_76908701 0.13 CTD-2373H9.5

9168
0.14
chr20_1359967_1360118 0.13 FKBP1A
FK506 binding protein 1A, 12kDa
13564
0.14
chr2_27110278_27110603 0.13 DPYSL5
dihydropyrimidinase-like 5
39064
0.12
chr4_83943782_83943933 0.13 LIN54
lin-54 homolog (C. elegans)
9778
0.16
chr22_26800846_26801092 0.13 ENSG00000252267
.
14227
0.17
chr21_40455880_40456270 0.13 PSMG1
proteasome (prosome, macropain) assembly chaperone 1
99339
0.07
chr17_42849030_42849346 0.13 ADAM11
ADAM metallopeptidase domain 11
12495
0.13
chr17_1959980_1960184 0.13 HIC1
hypermethylated in cancer 1
478
0.62
chr1_66777257_66777408 0.13 PDE4B
phosphodiesterase 4B, cAMP-specific
19079
0.28
chr12_112212431_112212814 0.13 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
7896
0.19
chr6_2825832_2826072 0.12 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
16142
0.17
chr8_37757773_37757924 0.12 RAB11FIP1
RAB11 family interacting protein 1 (class I)
863
0.51
chr6_6887247_6887398 0.12 ENSG00000240936
.
51808
0.17
chr9_124273187_124273484 0.12 ENSG00000240299
.
16538
0.18
chr11_34354091_34354256 0.12 ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
24629
0.23
chr5_137801463_137801649 0.12 EGR1
early growth response 1
377
0.84
chr12_112628379_112628530 0.12 HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
13948
0.17
chr15_94408923_94409174 0.12 ENSG00000222409
.
31208
0.26
chr6_137211819_137211970 0.12 SLC35D3
solute carrier family 35, member D3
31508
0.14
chr17_15845936_15846239 0.12 ADORA2B
adenosine A2b receptor
2144
0.31
chr20_36824784_36825086 0.12 TGM2
transglutaminase 2
29955
0.14
chr21_45123059_45123298 0.12 PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
15797
0.17
chr19_33770830_33771059 0.12 CTD-2540B15.11

19896
0.11
chr2_191506139_191506290 0.12 NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
5258
0.25
chr12_27702924_27703232 0.12 PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
12022
0.23
chr2_71687770_71687921 0.12 DYSF
dysferlin
5987
0.27
chr1_109681194_109681359 0.12 KIAA1324
KIAA1324
24499
0.11
chr5_154229551_154229702 0.12 FAXDC2
fatty acid hydroxylase domain containing 2
537
0.74
chr11_45944455_45944606 0.12 GYLTL1B
glycosyltransferase-like 1B
201
0.9
chr21_44817450_44817601 0.12 SIK1
salt-inducible kinase 1
29483
0.23
chr14_51544517_51544668 0.12 RP11-1140I5.1

11083
0.21
chr12_123921421_123921707 0.12 RILPL2
Rab interacting lysosomal protein-like 2
300
0.87
chr15_64283322_64283528 0.12 DAPK2
death-associated protein kinase 2
49041
0.12
chr6_6798807_6798985 0.12 ENSG00000240936
.
140234
0.05
chr11_65075775_65076171 0.12 CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
6316
0.13
chr14_59931229_59931380 0.12 GPR135
G protein-coupled receptor 135
756
0.65
chr10_93870631_93870837 0.12 ENSG00000252993
.
34735
0.16
chr10_30092663_30093124 0.12 SVIL
supervillin
68160
0.12
chr19_6059466_6059704 0.12 RFX2
regulatory factor X, 2 (influences HLA class II expression)
2291
0.23
chr6_150184862_150185013 0.12 LRP11
low density lipoprotein receptor-related protein 11
225
0.57
chr1_160254501_160254652 0.12 PEX19
peroxisomal biogenesis factor 19
340
0.46
chr10_82012381_82012532 0.12 AL359195.1
Uncharacterized protein; cDNA FLJ46261 fis, clone TESTI4025062
2990
0.26
chr15_29561544_29561695 0.12 NDNL2
necdin-like 2
414
0.88
chr9_99693594_99693748 0.12 NUTM2G
NUT family member 2G
2385
0.36
chr8_22953881_22954118 0.12 TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
6104
0.14
chr10_104957863_104958014 0.12 NT5C2
5'-nucleotidase, cytosolic II
4882
0.23
chr2_112400633_112400819 0.12 ENSG00000266063
.
127985
0.06
chr2_174889480_174890119 0.12 SP3
Sp3 transcription factor
59369
0.15
chr20_23008934_23009272 0.12 RP4-753D10.5

2319
0.23
chr9_113683953_113684408 0.12 ENSG00000207401
.
12506
0.22
chr5_142980288_142980439 0.12 CTB-57H20.1

4830
0.29
chr1_244505150_244505410 0.12 C1orf100
chromosome 1 open reading frame 100
10657
0.25
chr11_43810486_43810637 0.12 RP11-613D13.5

44906
0.15
chr9_97088395_97088740 0.12 NUTM2F
NUT family member 2F
2359
0.3
chr2_97870529_97870680 0.12 ANKRD36
ankyrin repeat domain 36
40976
0.13
chr8_72088568_72088719 0.12 RP11-326E22.1

20886
0.28
chr18_60646350_60646591 0.12 PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
76087
0.1
chr19_7720613_7720936 0.12 STXBP2
syntaxin binding protein 2
9929
0.08
chr8_9938557_9938708 0.12 ENSG00000221320
.
6799
0.21
chr12_48168957_48169108 0.12 SLC48A1
solute carrier family 48 (heme transporter), member 1
2041
0.23
chr6_43775268_43775445 0.12 VEGFA
vascular endothelial growth factor A
33266
0.15
chr8_1873489_1873640 0.12 ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
42742
0.16
chr14_75754946_75755194 0.12 FOS
FBJ murine osteosarcoma viral oncogene homolog
8174
0.17
chr1_27973206_27973357 0.12 FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
11493
0.12
chr4_172263778_172264007 0.12 ENSG00000251961
.
451274
0.01
chr9_97567295_97567893 0.12 ENSG00000252153
.
4650
0.2
chr20_19403915_19404216 0.11 ENSG00000221748
.
82125
0.1
chr4_86954647_86954929 0.11 RP13-514E23.1

19761
0.19
chr11_67859868_67860019 0.11 CHKA
choline kinase alpha
28352
0.1
chr16_85112017_85112168 0.11 KIAA0513
KIAA0513
67
0.98
chr16_85855178_85855329 0.11 COX4I1
cytochrome c oxidase subunit IV isoform 1
20445
0.12
chr12_96564682_96564833 0.11 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
23403
0.18
chr10_3612660_3612862 0.11 RP11-184A2.3

180498
0.03
chr1_204940620_204940796 0.11 NFASC
neurofascin
10276
0.21
chr15_41225289_41225440 0.11 DLL4
delta-like 4 (Drosophila)
3773
0.15
chr1_17609322_17609523 0.11 ENSG00000266634
.
5038
0.18
chr2_55347968_55348289 0.11 RTN4
reticulon 4
8371
0.19
chr15_81033301_81033659 0.11 KIAA1199
KIAA1199
38204
0.15
chr9_80564462_80564644 0.11 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
80967
0.11
chr20_19300587_19300738 0.11 ENSG00000221748
.
21278
0.21
chr17_14651949_14652297 0.11 HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
447723
0.01
chr19_10341033_10341420 0.11 ENSG00000264266
.
137
0.8
chr2_86642212_86642427 0.11 KDM3A
lysine (K)-specific demethylase 3A
25451
0.16
chr5_95003135_95003286 0.11 RFESD
Rieske (Fe-S) domain containing
13445
0.16
chr17_54040448_54040734 0.11 ENSG00000264277
.
91557
0.09
chr2_208497932_208498495 0.11 METTL21A
methyltransferase like 21A
7562
0.19
chr13_29170887_29171038 0.11 POMP
proteasome maturation protein
62279
0.13
chr12_109117281_109117726 0.11 CORO1C
coronin, actin binding protein, 1C
6824
0.16
chr19_35948719_35948870 0.11 FFAR2
free fatty acid receptor 2
8177
0.11
chr21_43723122_43723420 0.11 ENSG00000216197
.
2816
0.21
chr9_97338725_97338876 0.11 FBP2
fructose-1,6-bisphosphatase 2
17275
0.22
chr2_95941719_95941977 0.11 PROM2
prominin 2
1603
0.42
chr10_73628074_73628344 0.11 PSAP
prosaposin
17083
0.19
chr21_39640704_39640894 0.11 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
3373
0.34
chr20_22904829_22904980 0.11 RP4-753D10.5

106518
0.06
chr2_242843726_242843877 0.11 AC131097.4
Protein LOC285095
901
0.5
chr12_11992163_11992414 0.11 ETV6
ets variant 6
46583
0.19
chr21_38895077_38895228 0.11 AP001421.1
Uncharacterized protein
6412
0.26
chr3_53740550_53740701 0.11 CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
40197
0.16
chr6_13480251_13480456 0.11 AL583828.1

6062
0.17
chr9_130910949_130911100 0.11 LCN2
lipocalin 2
326
0.76
chr12_94566333_94566520 0.11 RP11-74K11.2

3754
0.26
chr9_83733305_83733456 0.11 ENSG00000221581
.
384136
0.01
chr3_46172431_46172582 0.11 CCR3
chemokine (C-C motif) receptor 3
32590
0.18
chr16_66262660_66262838 0.11 ENSG00000201999
.
72963
0.11
chr1_94018769_94019015 0.11 FNBP1L
formin binding protein 1-like
23625
0.16
chr10_119460300_119460451 0.11 EMX2OS
EMX2 opposite strand/antisense RNA
155796
0.04
chr6_144080973_144081159 0.11 PHACTR2
phosphatase and actin regulator 2
81861
0.09
chr4_6855596_6855818 0.11 TBC1D14
TBC1 domain family, member 14
55262
0.11
chr3_184335510_184335694 0.11 EPHB3
EPH receptor B3
56030
0.11
chr1_11004143_11004582 0.11 C1orf127
chromosome 1 open reading frame 127
3565
0.22
chr20_56045926_56046077 0.11 CTCFL
CCCTC-binding factor (zinc finger protein)-like
53312
0.11
chr19_12893778_12893929 0.11 ENSG00000263800
.
4089
0.08
chr22_39239357_39239520 0.11 NPTXR
neuronal pentraxin receptor
549
0.69
chr5_70883327_70883478 0.11 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
207
0.96
chr2_102733095_102733246 0.11 IL1R1
interleukin 1 receptor, type I
12141
0.23
chr14_69509818_69509969 0.11 ACTN1-AS1
ACTN1 antisense RNA 1
63135
0.11
chr20_55061855_55062036 0.11 ENSG00000238294
.
11246
0.12
chr1_161058959_161059110 0.11 PVRL4
poliovirus receptor-related 4
355
0.7
chr5_169908402_169908553 0.11 CTB-147C13.1

4934
0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of MYF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0052308 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0071397 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0 0.0 GO:0001845 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0034114 heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0 0.0 GO:0035608 protein deglutamylation(GO:0035608)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0043176 amine binding(GO:0043176)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.0 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions