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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NANOG

Z-value: 1.03

Motif logo

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Transcription factors associated with NANOG

Gene Symbol Gene ID Gene Info
NANOG
ENSG00000111704.6 Nanog homeobox

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_7945278_7945429NANOG31420.1467810.137.3e-01Click!
chr12_7945753_7945904NANOG36170.1369310.019.9e-01Click!
chr12_7946157_7946308NANOG40210.130954-0.019.9e-01Click!

Activity of the NANOG motif across conditions

Conditions sorted by the z-value of the NANOG motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_20557654_20557988 0.34 RP11-284H19.1
34625
 0.2
chr1_205670529_205670680 0.32 AC119673.1
11893
 0.14
chr3_49748675_49748961 0.30 RNF123
 ring finger protein 123
 1445
 0.27
chr3_149160811_149161262 0.30 TM4SF4
 transmembrane 4 L six family member 4
 30725
 0.16
chr16_49565236_49565387 0.29 ZNF423
 zinc finger protein 423
 109452
 0.07
chr11_32447864_32448015 0.28 WT1
 Wilms tumor 1
 2636
 0.33
chr3_121774222_121774373 0.27 CD86
 CD86 molecule
 76
 0.97
chr15_33299614_33299765 0.26 ENSG00000212415
 .
 36761
 0.19
chr1_25335272_25335426 0.26 ENSG00000264371
 .
 14645
 0.2
chr4_57909352_57909761 0.25 ENSG00000251703
 .
 40698
 0.11
chr8_96705142_96705479 0.25 ENSG00000223297
 .
 14167
 0.29
chr11_72985767_72986011 0.25 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
 2424
 0.23
chr2_62356561_62356823 0.24 COMMD1
 copper metabolism (Murr1) domain containing 1
 6288
 0.21
chr12_113308184_113308335 0.24 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
 36323
 0.15
chr1_26354858_26355009 0.24 EXTL1
 exostosin-like glycosyltransferase 1
 6662
 0.1
chr2_202083500_202083651 0.24 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 14591
 0.16
chr2_206648577_206648850 0.23 AC007362.3
19983
 0.24
chr8_104165322_104165473 0.23 ENSG00000265657
 .
 1445
 0.3
chr2_105594341_105594492 0.23 ENSG00000263685
 .
 15022
 0.19
chr17_32694389_32694669 0.22 CCL1
 chemokine (C-C motif) ligand 1
 4279
 0.2
chr17_78723949_78724201 0.22 RP11-28G8.1
55357
 0.14
chr3_37499337_37499488 0.22 ITGA9
 integrin, alpha 9
 5802
 0.25
chr8_24206460_24207135 0.22 ADAM28
 ADAM metallopeptidase domain 28
 7632
 0.22
chr8_6149074_6149420 0.22 RP11-115C21.2
114816
 0.06
chr4_173708241_173708420 0.22 ENSG00000241652
 .
 354464
 0.01
chr5_71768852_71769003 0.22 RP11-389C8.2
30713
 0.19
chr8_125434775_125435085 0.22 TRMT12
 tRNA methyltransferase 12 homolog (S. cerevisiae)
 28118
 0.16
chr12_6482203_6482355 0.21 SCNN1A
 sodium channel, non-voltage-gated 1 alpha subunit
 1690
 0.23
chr14_35837591_35837748 0.21 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 35677
 0.17
chr6_134537452_134537663 0.21 ENSG00000238631
 .
 9905
 0.2
chr2_231750819_231750970 0.21 AC012507.3
321
 0.87
chr10_80937857_80938019 0.20 ZMIZ1
 zinc finger, MIZ-type containing 1
 109146
 0.07
chr7_26685921_26686196 0.20 C7orf71
 chromosome 7 open reading frame 71
 8568
 0.29
chr15_81400350_81400501 0.20 C15orf26
 chromosome 15 open reading frame 26
 8676
 0.24
chr20_50010365_50010516 0.20 ENSG00000263645
 .
 16582
 0.25
chr2_42304204_42304355 0.20 PKDCC
 protein kinase domain containing, cytoplasmic
 29119
 0.18
chr9_129151715_129152192 0.20 MVB12B
 multivesicular body subunit 12B
 13231
 0.2
chr17_72599092_72599393 0.20 CD300LD
 CD300 molecule-like family member d
 10820
 0.12
chr16_23907560_23907711 0.20 PRKCB
 protein kinase C, beta
 59091
 0.13
chr12_12013798_12013949 0.20 ETV6
 ets variant 6
 24998
 0.26
chr19_17790984_17791135 0.19 UNC13A
 unc-13 homolog A (C. elegans)
 4081
 0.18
chr3_168931111_168931360 0.19 MECOM
 MDS1 and EVI1 complex locus
 55791
 0.17
chr18_46580939_46581171 0.19 ENSG00000263849
 .
 4917
 0.22
chr3_148477195_148477534 0.19 AGTR1
 angiotensin II receptor, type 1
 19779
 0.22
chr9_95823092_95823243 0.19 SUSD3
 sushi domain containing 3
 2106
 0.29
chr18_13268737_13268888 0.19 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 9290
 0.2
chr14_52782524_52782774 0.19 PTGER2
 prostaglandin E receptor 2 (subtype EP2), 53kDa
 1536
 0.5
chr16_46782782_46782933 0.19 MYLK3
 myosin light chain kinase 3
 636
 0.74
chr2_6920801_6920998 0.19 AC017076.5
52763
 0.14
chr16_81868234_81868705 0.19 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 48405
 0.17
chr19_11433238_11433389 0.19 CTC-510F12.6
481
 0.63
chr2_200527098_200527249 0.19 FTCDNL1
 formiminotransferase cyclodeaminase N-terminal like
 188423
 0.03
chr1_171624147_171624306 0.18 MYOC
 myocilin, trabecular meshwork inducible glucocorticoid response
 2403
 0.34
chr15_66938215_66938421 0.18 SMAD6
 SMAD family member 6
 56248
 0.1
chr11_109966413_109966654 0.18 ZC3H12C
 zinc finger CCCH-type containing 12C
 2446
 0.45
chr13_21620980_21621217 0.18 ENSG00000201821
 .
 8292
 0.15
chr12_2723257_2723602 0.18 CACNA1C-AS3
 CACNA1C antisense RNA 3
 6823
 0.24
chr17_72542253_72542431 0.18 CD300C
 CD300c molecule
 60
 0.96
chr19_12800165_12800409 0.18 CTD-2659N19.2
551
 0.5
chr2_145462594_145462835 0.18 ZEB2
 zinc finger E-box binding homeobox 2
 184093
 0.03
chr22_26047284_26047507 0.18 ENSG00000222585
 .
 63741
 0.09
chr1_153941559_153941710 0.18 CREB3L4
 cAMP responsive element binding protein 3-like 4
 848
 0.32
chr3_42068290_42068573 0.17 TRAK1
 trafficking protein, kinesin binding 1
 64131
 0.11
chr3_193564257_193564433 0.17 ENSG00000243991
 .
 105835
 0.07
chr14_63672742_63672893 0.17 RHOJ
 ras homolog family member J
 1240
 0.55
chr22_17739441_17739786 0.17 CECR1
 cat eye syndrome chromosome region, candidate 1
 36734
 0.16
chr16_6914698_6914849 0.17 ENSG00000200869
 .
 9127
 0.29
chr10_4927599_4927750 0.17 AKR1C1
 aldo-keto reductase family 1, member C1
 7122
 0.22
chr22_23933547_23933698 0.17 IGLL1
 immunoglobulin lambda-like polypeptide 1
 11127
 0.15
chr13_43919735_43919886 0.17 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 15403
 0.31
chr15_39687457_39687608 0.17 RP11-624L4.1
25378
 0.25
chr6_56194231_56194392 0.17 RP3-445N2.1
2604
 0.38
chr4_109454301_109454616 0.17 ENSG00000266046
 .
 43838
 0.17
chr5_177667409_177667628 0.17 PHYKPL
 5-phosphohydroxy-L-lysine phospho-lyase
 7732
 0.21
chr1_117040601_117040786 0.17 ENSG00000200547
 .
 45535
 0.11
chr14_75295916_75296067 0.17 YLPM1
 YLP motif containing 1
 12050
 0.14
chr5_139036948_139037177 0.17 CXXC5
 CXXC finger protein 5
 2078
 0.35
chr5_179588041_179588247 0.17 RASGEF1C
 RasGEF domain family, member 1C
 22795
 0.21
chr4_10706517_10706811 0.17 CLNK
 cytokine-dependent hematopoietic cell linker
 20175
 0.29
chr2_29415943_29416138 0.17 ALK
 anaplastic lymphoma receptor tyrosine kinase
 30220
 0.18
chr3_51555997_51556148 0.17 RAD54L2
 RAD54-like 2 (S. cerevisiae)
 19524
 0.18
chr7_142430889_142431059 0.17 PRSS1
 protease, serine, 1 (trypsin 1)
 26345
 0.17
chr5_134718436_134718820 0.16 H2AFY
 H2A histone family, member Y
 16273
 0.15
chr3_188139152_188139752 0.16 LPP-AS1
 LPP antisense RNA 1
 147002
 0.04
chr3_71976245_71976396 0.16 ENSG00000239250
 .
 99992
 0.08
chr1_205206275_205206426 0.16 RP11-383G10.5
355
 0.86
chr1_213499256_213499407 0.16 RPS6KC1
 ribosomal protein S6 kinase, 52kDa, polypeptide 1
 274727
 0.01
chr6_1850485_1850731 0.16 FOXC1
 forkhead box C1
 239927
 0.02
chr8_17004029_17004180 0.16 ZDHHC2
 zinc finger, DHHC-type containing 2
 9434
 0.25
chr6_169615307_169615476 0.16 XXyac-YX65C7_A.2
2042
 0.43
chr6_136748361_136748512 0.16 MAP7
 microtubule-associated protein 7
 39577
 0.18
chr19_19635191_19635342 0.16 YJEFN3
 YjeF N-terminal domain containing 3
 4404
 0.12
chr1_109934550_109935130 0.16 SORT1
 sortilin 1
 1139
 0.45
chr21_32641465_32641616 0.16 TIAM1
 T-cell lymphoma invasion and metastasis 1
 7543
 0.31
chr4_88628609_88628760 0.16 RP11-742B18.1
24838
 0.15
chr14_56880037_56880188 0.16 TMEM260
 transmembrane protein 260
 74960
 0.12
chr2_218776477_218776674 0.16 TNS1
 tensin 1
 6391
 0.26
chr4_16034919_16035070 0.16 ENSG00000251758
 .
 24584
 0.18
chr2_122572651_122572909 0.16 TSN
 translin
 59033
 0.13
chr3_150805055_150805642 0.16 MED12L
 mediator complex subunit 12-like
 667
 0.76
chr17_72387513_72387690 0.16 GPR142
 G protein-coupled receptor 142
 24004
 0.1
chr1_235055137_235055288 0.16 ENSG00000239690
 .
 15279
 0.26
chr12_102170928_102171079 0.16 ENSG00000201168
 .
 2589
 0.16
chr17_55082561_55082712 0.16 ENSG00000265809
 .
 2292
 0.23
chr7_150549245_150549396 0.16 AOC1
 amine oxidase, copper containing 1
 223
 0.93
chr16_70456809_70457112 0.16 ST3GAL2
 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
 16031
 0.11
chr15_45927791_45927942 0.16 SQRDL
 sulfide quinone reductase-like (yeast)
 928
 0.56
chr3_18022579_18022730 0.15 TBC1D5
 TBC1 domain family, member 5
 238510
 0.02
chr8_110032427_110032578 0.15 RP11-1084E5.1
43144
 0.18
chr3_37601222_37601385 0.15 ENSG00000239105
 .
 13401
 0.26
chr12_53026253_53026404 0.15 KRT73
 keratin 73
 13985
 0.1
chr12_26303323_26303715 0.15 SSPN
 sarcospan
 15619
 0.18
chr18_10354698_10354849 0.15 ENSG00000239031
 .
 35224
 0.21
chr5_82672926_82673088 0.15 VCAN
 versican
 94277
 0.09
chr9_92236942_92237093 0.15 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 17064
 0.27
chr1_108484035_108484186 0.15 VAV3-AS1
 VAV3 antisense RNA 1
 22955
 0.2
chr12_48111947_48112151 0.15 ENDOU
 endonuclease, polyU-specific
 617
 0.69
chr5_142076865_142077016 0.15 FGF1
 fibroblast growth factor 1 (acidic)
 646
 0.77
chr6_44537708_44537867 0.15 ENSG00000266619
 .
 134409
 0.05
chr12_6727682_6727833 0.15 CHD4
 chromodomain helicase DNA binding protein 4
 11115
 0.08
chr7_158505623_158505780 0.15 NCAPG2
 non-SMC condensin II complex, subunit G2
 8181
 0.23
chr6_6587145_6587296 0.15 LY86-AS1
 LY86 antisense RNA 1
 206
 0.91
chr1_244481954_244482146 0.15 C1orf100
 chromosome 1 open reading frame 100
 33887
 0.2
chr14_24041929_24042080 0.15 JPH4
 junctophilin 4
 206
 0.88
chr14_70171005_70171156 0.15 SRSF5
 serine/arginine-rich splicing factor 5
 22537
 0.21
chr17_76875045_76875748 0.15 TIMP2
 TIMP metallopeptidase inhibitor 2
 5164
 0.16
chr8_134038596_134039031 0.15 TG
 thyroglobulin
 8869
 0.25
chr3_58060016_58060182 0.15 FLNB
 filamin B, beta
 3957
 0.31
chr19_44038735_44038963 0.15 ZNF575
 zinc finger protein 575
 1284
 0.27
chr12_121136482_121136633 0.15 RP11-173P15.3
747
 0.48
chr22_42095499_42095650 0.15 MEI1
 meiosis inhibitor 1
 56
 0.95
chr19_7720613_7720936 0.15 STXBP2
 syntaxin binding protein 2
 9929
 0.08
chr9_124048116_124048398 0.15 GSN-AS1
 GSN antisense RNA 1
 449
 0.54
chr17_36582123_36582274 0.15 ARHGAP23
 Rho GTPase activating protein 23
 2464
 0.24
chr14_54810734_54810960 0.15 CDKN3
 cyclin-dependent kinase inhibitor 3
 52826
 0.16
chr13_101259048_101259199 0.15 GGACT
 gamma-glutamylamine cyclotransferase
 17341
 0.19
chrX_123512646_123512832 0.15 SH2D1A
 SH2 domain containing 1A
 32300
 0.24
chr12_111836596_111836747 0.15 SH2B3
 SH2B adaptor protein 3
 7081
 0.19
chr13_24612924_24613153 0.14 SPATA13
 spermatogenesis associated 13
 59094
 0.12
chr17_63367349_63367500 0.14 ENSG00000265189
 .
 49354
 0.18
chr5_111089659_111089857 0.14 NREP
 neuronal regeneration related protein
 2190
 0.34
chr8_125663658_125664035 0.14 RP11-532M24.1
71974
 0.09
chr4_139327703_139328022 0.14 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 164359
 0.04
chr15_65871486_65871637 0.14 ENSG00000238715
 .
 8150
 0.13
chr2_223733795_223733969 0.14 ACSL3
 acyl-CoA synthetase long-chain family member 3
 7601
 0.24
chr3_13056298_13056451 0.14 IQSEC1
 IQ motif and Sec7 domain 1
 27838
 0.23
chr17_26846701_26846852 0.14 FOXN1
 forkhead box N1
 4183
 0.11
chr21_43728792_43729093 0.14 TFF3
 trefoil factor 3 (intestinal)
 6504
 0.15
chr11_73083087_73083238 0.14 RELT
 RELT tumor necrosis factor receptor
 4147
 0.17
chr6_26485880_26486031 0.14 BTN1A1
 butyrophilin, subfamily 1, member A1
 15494
 0.11
chr8_59583399_59583550 0.14 ENSG00000238433
 .
 8571
 0.23
chr1_159173730_159173881 0.14 DARC
 Duffy blood group, atypical chemokine receptor
 266
 0.86
chr5_485358_485509 0.14 ENSG00000225138
 .
 8073
 0.13
chr1_167073679_167073835 0.14 DUSP27
 dual specificity phosphatase 27 (putative)
 9670
 0.17
chr3_29452909_29453060 0.14 ENSG00000216169
 .
 42072
 0.2
chr3_69789465_69789616 0.14 MITF
 microphthalmia-associated transcription factor
 918
 0.68
chr1_161038891_161039092 0.14 ARHGAP30
 Rho GTPase activating protein 30
 465
 0.61
chr9_134752156_134752307 0.14 ENSG00000212395
 .
 93886
 0.08
chr4_144296712_144296863 0.14 GAB1
 GRB2-associated binding protein 1
 1191
 0.54
chr1_46032186_46032337 0.14 AKR1A1
 aldo-keto reductase family 1, member A1 (aldehyde reductase)
 15521
 0.14
chr1_56942791_56942942 0.14 ENSG00000223307
 .
 99776
 0.08
chr22_25128279_25128430 0.14 PIWIL3
 piwi-like RNA-mediated gene silencing 3
 42090
 0.15
chr4_8404089_8404323 0.14 ENSG00000202054
 .
 9464
 0.18
chr10_72271972_72272123 0.14 PALD1
 phosphatase domain containing, paladin 1
 33470
 0.16
chr13_111169859_111170091 0.14 COL4A2-AS1
 COL4A2 antisense RNA 1
 9449
 0.21
chr20_40072604_40072755 0.14 CHD6
 chromodomain helicase DNA binding protein 6
 55278
 0.13
chr10_125826370_125826646 0.14 CHST15
 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
 20267
 0.26
chr2_145237384_145237678 0.14 ZEB2
 zinc finger E-box binding homeobox 2
 37584
 0.19
chr19_55142266_55142451 0.14 LILRB1
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
 167
 0.89
chr3_185463236_185463533 0.14 ENSG00000265470
 .
 22308
 0.19
chr18_22677589_22677740 0.14 ZNF521
 zinc finger protein 521
 127089
 0.06
chr2_46574762_46574949 0.14 EPAS1
 endothelial PAS domain protein 1
 50314
 0.15
chr12_48554479_48554630 0.14 ASB8
 ankyrin repeat and SOCS box containing 8
 3176
 0.17
chr2_182284878_182285029 0.14 ITGA4
 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
 36981
 0.21
chr8_105800425_105800620 0.14 ENSG00000263732
 .
 33119
 0.24
chr20_19373243_19373394 0.14 ENSG00000221748
 .
 51378
 0.16
chrX_77374906_77375064 0.14 PGK1
 phosphoglycerate kinase 1
 13126
 0.23
chr6_6588189_6588340 0.14 LY86
 lymphocyte antigen 86
 77
 0.94
chr18_46199452_46199714 0.14 ENSG00000266276
 .
 2612
 0.32
chr5_373044_373258 0.14 AHRR
 aryl-hydrocarbon receptor repressor
 29508
 0.14
chr10_97995296_97995447 0.14 BLNK
 B-cell linker
 35784
 0.16
chr10_130978330_130978481 0.14 MGMT
 O-6-methylguanine-DNA methyltransferase
 287043
 0.01
chr10_98524301_98524550 0.14 ENSG00000207287
 .
 21501
 0.18
chr7_99797920_99798071 0.14 STAG3
 stromal antigen 3
 4901
 0.09
chr11_2935428_2935683 0.14 SLC22A18AS
 solute carrier family 22 (organic cation transporter), member 18 antisense
 10585
 0.11
chr18_60561889_60562040 0.14 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
 8419
 0.25
chr7_151542313_151542464 0.14 PRKAG2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 30462
 0.13
chr14_100481690_100481841 0.14 EVL
 Enah/Vasp-like
 3954
 0.23
chr22_27530704_27530861 0.13 ENSG00000200443
 .
 98932
 0.09
chr2_136577229_136577614 0.13 AC011893.3
340
 0.86
chr1_183880847_183880998 0.13 COLGALT2
 collagen beta(1-O)galactosyltransferase 2
 34830
 0.2
chr18_35302652_35302803 0.13 ENSG00000266530
 .
 65629
 0.15
chr5_39400930_39401193 0.13 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 6559
 0.27
chr9_94065201_94065395 0.13 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 58879
 0.16
chr7_132139041_132139287 0.13 AC011625.1
102071
 0.08
chr1_27626590_27626805 0.13 TMEM222
 transmembrane protein 222
 21954
 0.11
chr18_53780471_53780622 0.13 ENSG00000201816
 .
 33721
 0.25
chr16_86632416_86632567 0.13 FOXL1
 forkhead box L1
 20376
 0.17
chr11_71844321_71844472 0.13 FOLR3
 folate receptor 3 (gamma)
 2360
 0.15
chr5_82297884_82298035 0.13 ENSG00000238835
 .
 62197
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NANOG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0051709 regulation of killing of cells of other organism(GO:0051709)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0071605 monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0 0.0 GO:0032682 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events