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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for NFATC1

Z-value: 1.61

Motif logo

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 nuclear factor of activated T cells 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr18_77159160_77159516NFATC19840.631431-0.941.3e-04Click!
chr18_77164936_77165190NFATC146710.275487-0.881.6e-03Click!
chr18_77166940_77167091NFATC166230.257756-0.863.0e-03Click!
chr18_77154994_77155234NFATC17420.728425-0.844.9e-03Click!
chr18_77165231_77165672NFATC150590.270449-0.845.1e-03Click!

Activity of the NFATC1 motif across conditions

Conditions sorted by the z-value of the NFATC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr21_35902480_35902631 0.54 RCAN1
 regulator of calcineurin 1
 3294
 0.26
chr9_127104782_127105372 0.46 ENSG00000264237
 .
 7733
 0.2
chr5_55164394_55164545 0.44 IL31RA
 interleukin 31 receptor A
 15111
 0.19
chr10_114863343_114863771 0.44 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
 40122
 0.21
chr11_121501091_121501242 0.43 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 40038
 0.22
chr20_10055682_10055833 0.41 ENSG00000264599
 .
 18789
 0.2
chr1_6301763_6302398 0.41 HES3
 hes family bHLH transcription factor 3
 2172
 0.18
chr21_17944689_17944974 0.40 ENSG00000207863
 .
 17726
 0.2
chr5_179246518_179247261 0.37 SQSTM1
 sequestosome 1
 870
 0.42
chr6_132511743_132511894 0.37 ENSG00000265669
 .
 75415
 0.11
chr11_61690283_61690510 0.37 RAB3IL1
 RAB3A interacting protein (rabin3)-like 1
 2655
 0.18
chr14_69388884_69389440 0.37 ACTN1
 actinin, alpha 1
 25103
 0.2
chr11_19627998_19628149 0.36 ENSG00000207407
 .
 15235
 0.2
chr8_141364670_141364821 0.36 TRAPPC9
 trafficking protein particle complex 9
 96284
 0.08
chr7_137353876_137354027 0.36 DGKI
 diacylglycerol kinase, iota
 177331
 0.03
chr7_151182024_151182303 0.36 ENSG00000241959
 .
 20139
 0.13
chr15_33148725_33148876 0.35 FMN1
 formin 1
 31655
 0.17
chr2_47416519_47416670 0.35 CALM2
 calmodulin 2 (phosphorylase kinase, delta)
 12854
 0.21
chr11_35448443_35448594 0.35 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 6908
 0.22
chr6_82317027_82317178 0.35 ENSG00000212336
 .
 14815
 0.23
chr6_56555787_56555938 0.35 DST
 dystonin
 48068
 0.18
chr1_219616434_219616585 0.35 ENSG00000252240
 .
 220210
 0.02
chr2_216523684_216523835 0.35 ENSG00000212055
 .
 219883
 0.02
chr16_15533494_15533711 0.35 C16orf45
 chromosome 16 open reading frame 45
 5270
 0.21
chr9_4303266_4303417 0.35 GLIS3
 GLIS family zinc finger 3
 3425
 0.25
chr6_148589578_148589729 0.35 SASH1
 SAM and SH3 domain containing 1
 3787
 0.25
chr6_128390231_128390382 0.34 PTPRK
 protein tyrosine phosphatase, receptor type, K
 4398
 0.3
chr4_71532339_71532558 0.34 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
 71
 0.96
chr7_116804373_116804524 0.34 ST7-AS2
 ST7 antisense RNA 2
 17914
 0.23
chr1_78721233_78721384 0.34 ENSG00000237413
 .
 26002
 0.2
chr4_157888355_157888628 0.33 PDGFC
 platelet derived growth factor C
 3564
 0.27
chr12_63155045_63155196 0.33 ENSG00000200296
 .
 89561
 0.08
chr11_11995194_11995345 0.33 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 34861
 0.21
chr8_108518687_108518838 0.33 ANGPT1
 angiopoietin 1
 8479
 0.33
chr3_149833178_149833329 0.33 RP11-167H9.4
17434
 0.21
chr6_128529618_128529908 0.33 PTPRK
 protein tyrosine phosphatase, receptor type, K
 113563
 0.07
chr18_52920557_52920708 0.33 TCF4
 transcription factor 4
 22270
 0.26
chr4_114304726_114304877 0.32 ANK2
 ankyrin 2, neuronal
 10286
 0.22
chr8_32530949_32531215 0.32 NRG1
 neuregulin 1
 25725
 0.27
chr13_24617983_24618134 0.32 SPATA13
 spermatogenesis associated 13
 64114
 0.11
chr4_186578170_186578442 0.32 SORBS2
 sorbin and SH3 domain containing 2
 183
 0.95
chr8_120615500_120615651 0.32 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 10327
 0.27
chr5_15249746_15249921 0.32 ENSG00000202269
 .
 138804
 0.05
chr4_79487146_79487361 0.32 ANXA3
 annexin A3
 12179
 0.24
chr2_69518306_69518457 0.32 ENSG00000252250
 .
 43351
 0.15
chr13_75942001_75942152 0.32 TBC1D4-AS1
 TBC1D4 antisense RNA 1
 9354
 0.24
chr6_116685228_116685657 0.31 DSE
 dermatan sulfate epimerase
 5568
 0.22
chr13_74792422_74792795 0.31 ENSG00000206617
 .
 70743
 0.12
chr11_121963341_121963492 0.31 ENSG00000207971
 .
 7136
 0.17
chr2_177392067_177392218 0.31 ENSG00000252027
 .
 137262
 0.04
chr5_43781026_43781177 0.31 NNT
 nicotinamide nucleotide transhydrogenase
 135642
 0.05
chr14_100240950_100241315 0.31 EML1
 echinoderm microtubule associated protein like 1
 1091
 0.59
chr9_79075654_79076239 0.31 GCNT1
 glucosaminyl (N-acetyl) transferase 1, core 2
 1800
 0.46
chr22_28625991_28626142 0.31 ENSG00000201209
 .
 2745
 0.37
chr5_54157834_54157985 0.31 ENSG00000221073
 .
 9133
 0.26
chr14_72142038_72142189 0.31 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 56640
 0.17
chr6_132301065_132301216 0.30 CTGF
 connective tissue growth factor
 28627
 0.18
chr6_72121829_72121980 0.30 ENSG00000207827
 .
 8580
 0.23
chr16_55520614_55520898 0.30 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
 1818
 0.4
chr1_96831244_96831395 0.30 ENSG00000200800
 .
 139862
 0.05
chr9_103340467_103340618 0.30 MURC
 muscle-related coiled-coil protein
 181
 0.95
chr12_26430442_26430909 0.30 RP11-283G6.5
5822
 0.22
chr3_105510379_105510530 0.30 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 77433
 0.13
chr1_214647384_214647535 0.30 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 9313
 0.29
chr11_112112150_112112301 0.30 ENSG00000215954
 .
 6328
 0.12
chr11_77313091_77313242 0.30 ENSG00000271767
 .
 6942
 0.16
chr3_124827683_124827880 0.30 ENSG00000199327
 .
 10263
 0.17
chr6_143670247_143670398 0.29 AL031320.1
89253
 0.07
chr9_21656575_21656726 0.29 ENSG00000244230
 .
 42663
 0.15
chr11_102009263_102009414 0.29 YAP1
 Yes-associated protein 1
 26093
 0.15
chr2_223920021_223920251 0.29 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
 3274
 0.35
chr10_19026308_19026459 0.29 ARL5B
 ADP-ribosylation factor-like 5B
 78049
 0.1
chr20_6685250_6685401 0.29 BMP2
 bone morphogenetic protein 2
 62986
 0.15
chr2_9517769_9518003 0.29 ITGB1BP1
 integrin beta 1 binding protein 1
 42537
 0.15
chr12_107368695_107368994 0.29 C12orf23
 chromosome 12 open reading frame 23
 8131
 0.17
chr4_77725622_77725773 0.29 RP11-359D14.3
2580
 0.3
chr18_56247923_56248074 0.29 ENSG00000252284
 .
 19865
 0.14
chr8_21766211_21767399 0.29 DOK2
 docking protein 2, 56kDa
 4369
 0.22
chr5_71747550_71747979 0.29 RP11-389C8.2
9550
 0.25
chr8_131245327_131245615 0.29 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 13817
 0.26
chr9_18479738_18479998 0.29 ADAMTSL1
 ADAMTS-like 1
 5637
 0.32
chr9_113639802_113639953 0.29 ENSG00000206923
 .
 25740
 0.21
chr15_101711256_101711683 0.29 CHSY1
 chondroitin sulfate synthase 1
 80668
 0.08
chr10_17220959_17221110 0.28 TRDMT1
 tRNA aspartic acid methyltransferase 1
 4375
 0.22
chr5_158173853_158174004 0.28 CTD-2363C16.1
236086
 0.02
chr5_149519603_149519837 0.28 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 2720
 0.21
chr2_109857650_109857801 0.28 ENSG00000265965
 .
 72356
 0.11
chr5_39524488_39524639 0.28 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 62161
 0.15
chr14_51228839_51228990 0.28 NIN
 ninein (GSK3B interacting protein)
 4599
 0.2
chr3_132324789_132324940 0.28 ACKR4
 atypical chemokine receptor 4
 8783
 0.22
chr2_100591017_100591168 0.28 AFF3
 AF4/FMR2 family, member 3
 129900
 0.05
chr11_73990200_73990857 0.28 ENSG00000206913
 .
 26931
 0.14
chr22_40705760_40705911 0.28 ADSL
 adenylosuccinate lyase
 36672
 0.14
chr18_32382440_32382591 0.28 DTNA
 dystrobrevin, alpha
 15411
 0.2
chr1_175946929_175947183 0.28 ENSG00000252906
 .
 9380
 0.26
chr4_40889441_40889724 0.28 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 2860
 0.27
chr4_54717943_54718094 0.28 RP11-89B16.1
48020
 0.17
chr5_64487632_64487783 0.28 ENSG00000207439
 .
 68511
 0.14
chr1_173310923_173311074 0.28 ENSG00000251817
 .
 60782
 0.13
chr8_49431262_49431413 0.28 RP11-770E5.1
32790
 0.24
chr8_8537594_8537745 0.28 CLDN23
 claudin 23
 21779
 0.21
chr1_56181953_56182104 0.28 PIGQP1
 phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
 222925
 0.02
chr6_107978488_107978941 0.28 SCML4
 sex comb on midleg-like 4 (Drosophila)
 74885
 0.11
chr10_15528350_15528501 0.28 FAM171A1
 family with sequence similarity 171, member A1
 115364
 0.07
chrX_13269027_13269605 0.28 GS1-600G8.3
59455
 0.14
chr7_137521422_137521598 0.28 DGKI
 diacylglycerol kinase, iota
 9772
 0.27
chr10_657520_657671 0.28 RP11-809C18.3
16983
 0.15
chr9_97703502_97703653 0.28 RP11-54O15.3
6349
 0.2
chr6_19698381_19698532 0.28 ENSG00000200957
 .
 55696
 0.16
chr11_95838965_95839116 0.28 MTMR2
 myotubularin related protein 2
 181581
 0.03
chr2_36666145_36666296 0.28 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 74613
 0.1
chr17_25642061_25642212 0.27 WSB1
 WD repeat and SOCS box containing 1
 20764
 0.2
chr11_123059894_123060045 0.27 CTD-2216M2.1
459
 0.83
chr3_148898157_148898308 0.27 CP
 ceruloplasmin (ferroxidase)
 824
 0.65
chr7_13782821_13782972 0.27 ETV1
 ets variant 1
 243170
 0.02
chr17_32580574_32580862 0.27 CCL2
 chemokine (C-C motif) ligand 2
 1586
 0.24
chr22_47426182_47426436 0.27 ENSG00000221672
 .
 182506
 0.03
chr7_15841281_15841432 0.27 MEOX2
 mesenchyme homeobox 2
 114919
 0.07
chr7_90346858_90347009 0.27 CDK14
 cyclin-dependent kinase 14
 7757
 0.3
chr3_55191596_55191747 0.27 LRTM1
 leucine-rich repeats and transmembrane domains 1
 190556
 0.03
chr2_120996591_120996972 0.27 RALB
 v-ral simian leukemia viral oncogene homolog B
 859
 0.59
chr5_76463438_76463589 0.27 ZBED3-AS1
 ZBED3 antisense RNA 1
 28439
 0.15
chr5_169134550_169134701 0.27 DOCK2
 dedicator of cytokinesis 2
 3672
 0.33
chr10_74496065_74496270 0.27 ENSG00000266719
 .
 15380
 0.16
chr2_237928848_237928999 0.27 ENSG00000202341
 .
 4975
 0.25
chr13_76359048_76359199 0.27 LMO7
 LIM domain 7
 3851
 0.31
chr13_32914724_32915103 0.27 BRCA2
 breast cancer 2, early onset
 25271
 0.15
chr12_26150271_26150549 0.27 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 2473
 0.34
chr6_100715988_100716139 0.27 RP1-121G13.2
158931
 0.04
chr11_94526714_94526894 0.27 AMOTL1
 angiomotin like 1
 25267
 0.2
chr16_87891158_87892093 0.27 SLC7A5
 solute carrier family 7 (amino acid transporter light chain, L system), member 5
 5620
 0.19
chr22_47149537_47150247 0.27 CTA-29F11.1
8568
 0.18
chr2_161232105_161232912 0.27 ENSG00000252465
 .
 20971
 0.19
chr5_71441214_71441365 0.27 ENSG00000264099
 .
 24005
 0.21
chr15_45381136_45381287 0.27 RP11-109D20.2
14965
 0.09
chr2_151412177_151412328 0.27 RND3
 Rho family GTPase 3
 16727
 0.31
chr7_1499695_1500152 0.27 AC102953.4
350
 0.72
chr4_150087781_150087932 0.26 ENSG00000239168
 .
 175071
 0.04
chr10_60838878_60839029 0.26 PHYHIPL
 phytanoyl-CoA 2-hydroxylase interacting protein-like
 97397
 0.09
chr2_158029538_158029689 0.26 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 84497
 0.1
chr2_191910102_191910403 0.26 ENSG00000231858
 .
 24000
 0.15
chr5_39419337_39419488 0.26 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 5558
 0.3
chr7_93954349_93954500 0.26 COL1A2
 collagen, type I, alpha 2
 69449
 0.13
chr4_7905515_7905666 0.26 AFAP1
 actin filament associated protein 1
 31550
 0.17
chr1_78769110_78769410 0.26 PTGFR
 prostaglandin F receptor (FP)
 308
 0.93
chr8_131244504_131244746 0.26 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 14663
 0.26
chr12_115372372_115372523 0.26 ENSG00000252459
 .
 196938
 0.03
chr3_124764370_124764521 0.26 HEG1
 heart development protein with EGF-like domains 1
 10357
 0.19
chr16_20891936_20892087 0.26 DCUN1D3
 DCN1, defective in cullin neddylation 1, domain containing 3
 11709
 0.15
chr2_85484950_85485101 0.26 ENSG00000221579
 .
 41132
 0.09
chr17_41016311_41016609 0.26 AOC4P
 amine oxidase, copper containing 4, pseudogene
 2836
 0.12
chr1_235053615_235054079 0.26 ENSG00000239690
 .
 13914
 0.26
chr1_66267521_66267672 0.26 PDE4B
 phosphodiesterase 4B, cAMP-specific
 8732
 0.26
chr18_21110127_21110312 0.26 NPC1
 Niemann-Pick disease, type C1
 3185
 0.23
chr2_208121057_208121376 0.26 AC007879.5
2240
 0.34
chr15_100051927_100052783 0.26 AC015660.1
 HCG1993240; Serologically defined breast cancer antigen NY-BR-40; Uncharacterized protein
 13777
 0.21
chr9_73204265_73204416 0.26 ENSG00000272232
 .
 9963
 0.28
chr16_9212818_9212969 0.26 RP11-473I1.10
11795
 0.16
chr16_84858002_84858153 0.26 RP11-254F19.2
3792
 0.21
chr16_66150653_66150937 0.26 ENSG00000201999
 .
 184917
 0.03
chr2_45581409_45581560 0.26 SRBD1
 S1 RNA binding domain 1
 213670
 0.02
chr1_236827406_236827557 0.26 ACTN2
 actinin, alpha 2
 22273
 0.21
chr1_179322658_179322809 0.26 ENSG00000263633
 .
 10715
 0.19
chr7_100067086_100067551 0.26 TSC22D4
 TSC22 domain family, member 4
 1619
 0.17
chr1_26113882_26114033 0.26 SEPN1
 selenoprotein N, 1
 12710
 0.11
chr22_43000472_43000822 0.26 POLDIP3
 polymerase (DNA-directed), delta interacting protein 3
 1675
 0.23
chr5_138164777_138164928 0.25 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
 44875
 0.12
chr8_121275153_121275304 0.25 COL14A1
 collagen, type XIV, alpha 1
 66073
 0.14
chr2_218723877_218724028 0.25 TNS1
 tensin 1
 17069
 0.25
chr5_79887117_79887268 0.25 ANKRD34B
 ankyrin repeat domain 34B
 20885
 0.16
chr1_85809222_85809373 0.25 ENSG00000264380
 .
 59004
 0.09
chr2_163053003_163053154 0.25 AC007750.5
36750
 0.15
chr5_111084347_111084498 0.25 NREP
 neuronal regeneration related protein
 7526
 0.21
chr11_130272299_130272590 0.25 ADAMTS8
 ADAM metallopeptidase with thrombospondin type 1 motif, 8
 26444
 0.2
chr4_72061057_72061208 0.25 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 8088
 0.31
chr13_30426801_30426952 0.25 UBL3
 ubiquitin-like 3
 2055
 0.46
chr6_85257015_85257166 0.25 RP11-132M7.3
142053
 0.05
chr6_75853592_75853743 0.25 COL12A1
 collagen, type XII, alpha 1
 8238
 0.28
chr15_32815666_32815817 0.25 AC135983.2
 Protein LOC100996413
 40919
 0.1
chr8_119757469_119757620 0.25 SAMD12
 sterile alpha motif domain containing 12
 123310
 0.06
chr3_73119570_73119721 0.25 PPP4R2
 protein phosphatase 4, regulatory subunit 2
 6480
 0.15
chr12_65926260_65926711 0.25 MSRB3
 methionine sulfoxide reductase B3
 205830
 0.02
chr12_116966140_116966291 0.25 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 30971
 0.22
chr3_196870510_196870661 0.25 DLG1
 discs, large homolog 1 (Drosophila)
 39920
 0.16
chr3_177186614_177186765 0.25 ENSG00000252028
 .
 34651
 0.24
chr13_45478155_45478306 0.25 NUFIP1
 nuclear fragile X mental retardation protein interacting protein 1
 85388
 0.08
chr1_100056261_100056412 0.25 PALMD
 palmdelphin
 55163
 0.15
chr4_26022444_26022595 0.25 SMIM20
 small integral membrane protein 20
 106588
 0.07
chr3_187989530_187989681 0.25 LPP
 LIM domain containing preferred translocation partner in lipoma
 31953
 0.22
chr6_131360559_131360710 0.25 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 23082
 0.26
chr16_70736623_70736774 0.25 VAC14
 Vac14 homolog (S. cerevisiae)
 2550
 0.22
chr3_72537234_72537495 0.25 RYBP
 RING1 and YY1 binding protein
 41295
 0.18
chr6_125583374_125583525 0.25 HDDC2
 HD domain containing 2
 39634
 0.18
chr15_48995639_48995790 0.25 FBN1
 fibrillin 1
 57668
 0.12
chr15_69596184_69596335 0.25 PAQR5
 progestin and adipoQ receptor family member V
 4968
 0.14
chr15_67289212_67289363 0.25 SMAD3
 SMAD family member 3
 66814
 0.13
chr11_76050281_76050680 0.25 PRKRIR
 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
 41506
 0.11
chr17_59295493_59295787 0.25 RP11-136H19.1
82315
 0.08
chr10_89300723_89300874 0.25 ENSG00000222192
 .
 22145
 0.19
chr11_118789955_118791011 0.24 BCL9L
 B-cell CLL/lymphoma 9-like
 870
 0.37

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.3 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.1 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.5 GO:0007567 parturition(GO:0007567)
0.1 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0051284 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060900 optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0003308 regulation of Wnt signaling pathway involved in heart development(GO:0003307) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.0 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.2 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.1 GO:0031394 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.0 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.0 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.0 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0021930 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0065005 protein-lipid complex assembly(GO:0065005)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0070099 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) Roundabout signaling pathway(GO:0035385) regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0032222 regulation of synaptic transmission, cholinergic(GO:0032222)
0.0 0.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0060433 bronchus development(GO:0060433)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0043656 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0043197 dendritic spine(GO:0043197)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening