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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for NFE2L1

Z-value: 3.85

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Transcription factors associated with NFE2L1

Gene Symbol	Gene ID	Gene Info
NFE2L1 Ensembl NCBI GeneCards UniProt	ENSG00000082641.11	NFE2L1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
NFE2L1	chr17_46126502_46126784	149	0.881288	-0.81	8.4e-03	Click!
NFE2L1	chr17_46127040_46127486	769	0.410027	-0.64	6.4e-02	Click!
NFE2L1	chr17_46129481_46129645	2127	0.154438	-0.39	3.0e-01	Click!
NFE2L1	chr17_46128188_46128339	1769	0.178230	0.34	3.7e-01	Click!
NFE2L1	chr17_46129025_46129254	2551	0.133542	-0.27	4.8e-01	Click!

Activity of the NFE2L1 motif across conditions

Conditions sorted by the z-value of the NFE2L1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_640639_641593	2.25	RAB40C	RAB40C, member RAS oncogene family	784	0.37
chr1_26610395_26611734	0.89	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	4451	0.13
chr3_141126707_141127060	0.82	ZBTB38	zinc finger and BTB domain containing 38	5223	0.26
chr19_1168901_1169806	0.80	SBNO2	strawberry notch homolog 2 (Drosophila)	411	0.76
chr5_111304224_111304663	0.79	NREP-AS1	NREP antisense RNA 1	706	0.74
chr6_35393359_35394053	0.76	FANCE	Fanconi anemia, complementation group E	26432	0.15
chr16_88340108_88340439	0.75	ZNF469	zinc finger protein 469	153606	0.04
chr4_72242987_72243266	0.75	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	38356	0.23
chr2_36757574_36758239	0.71	RP11-78I14.1		17031	0.17
chr6_167034580_167034808	0.69	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	6031	0.28
chr5_52105602_52106304	0.67	CTD-2288O8.1		22093	0.18
chr4_77906953_77907316	0.67	SEPT11	septin 11	957	0.65
chr3_45589006_45589723	0.65	LARS2-AS1	LARS2 antisense RNA 1	38327	0.14
chr5_77843164_77843651	0.65	LHFPL2	lipoma HMGIC fusion partner-like 2	1567	0.55
chr9_128507884_128508777	0.65	PBX3	pre-B-cell leukemia homeobox 3	1294	0.56
chr1_39916771_39917068	0.65	MACF1	microtubule-actin crosslinking factor 1	2590	0.26
chr1_162690967_162691118	0.64	DDR2	discoidin domain receptor tyrosine kinase 2	45985	0.13
chr7_28667262_28667791	0.64	CREB5	cAMP responsive element binding protein 5	18848	0.29
chr5_71441214_71441365	0.63	ENSG00000264099	.	24005	0.21
chr18_43168412_43168563	0.63	SLC14A2	solute carrier family 14 (urea transporter), member 2	26279	0.19
chr2_19986384_19986783	0.62	TTC32	tetratricopeptide repeat domain 32	114819	0.06
chr6_144007887_144008177	0.62	PHACTR2	phosphatase and actin regulator 2	8827	0.27
chr14_53834899_53835050	0.61	RP11-547D23.1		214902	0.02
chr11_70261652_70262194	0.61	CTTN	cortactin	4308	0.17
chr1_66735904_66736482	0.61	PDE4B	phosphodiesterase 4B, cAMP-specific	12863	0.3
chr5_100760236_100760486	0.61	ENSG00000264318	.	157173	0.04
chr10_103369371_103369522	0.61	ENSG00000263436	.	8272	0.15
chr13_47149189_47149835	0.61	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	22117	0.25
chr8_21766211_21767399	0.60	DOK2	docking protein 2, 56kDa	4369	0.22
chr1_109740426_109740857	0.60	ENSG00000238310	.	9829	0.15
chr2_200138131_200138282	0.60	RP11-486F17.1		51827	0.17
chr15_89710472_89711584	0.60	RLBP1	retinaldehyde binding protein 1	44046	0.12
chr11_73024899_73025487	0.60	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	2583	0.2
chr4_141177038_141177320	0.58	SCOC	short coiled-coil protein	1261	0.51
chr3_134396340_134396760	0.58	KY	kyphoscoliosis peptidase	26686	0.2
chr17_42872109_42872587	0.58	GJC1	gap junction protein, gamma 1, 45kDa	9986	0.14
chr21_40561834_40561985	0.58	AF129408.17		5514	0.18
chr4_120130830_120131163	0.57	RP11-455G16.1	Uncharacterized protein	2671	0.26
chr7_139420465_139421101	0.57	HIPK2	homeodomain interacting protein kinase 2	1058	0.64
chr18_20945412_20945694	0.57	TMEM241	transmembrane protein 241	72264	0.09
chr8_126582644_126582795	0.57	ENSG00000266452	.	125912	0.06
chr3_100621330_100621481	0.57	ABI3BP	ABI family, member 3 (NESH) binding protein	11903	0.26
chr3_114789964_114790115	0.57	ZBTB20	zinc finger and BTB domain containing 20	183	0.98
chr5_106972962_106973113	0.57	EFNA5	ephrin-A5	33291	0.23
chr21_30706775_30707487	0.56	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	7534	0.17
chr1_78721233_78721384	0.56	ENSG00000237413	.	26002	0.2
chr1_82172475_82172626	0.56	LPHN2	latrophilin 2	7095	0.3
chr4_187565964_187566324	0.56	FAT1	FAT atypical cadherin 1	46966	0.16
chr1_209780440_209781046	0.56	LAMB3	laminin, beta 3	11400	0.16
chr2_160890400_160890551	0.56	PLA2R1	phospholipase A2 receptor 1, 180kDa	28646	0.23
chr15_99489885_99490412	0.56	IGF1R	insulin-like growth factor 1 receptor	22319	0.19
chr18_67715103_67715254	0.56	RTTN	rotatin	27224	0.24
chr5_149519603_149519837	0.55	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	2720	0.21
chr7_6056109_6056260	0.55	ENSG00000207217	.	324	0.77
chr19_16961262_16961630	0.55	CTD-2538G9.5		6610	0.13
chr14_52519690_52519841	0.55	NID2	nidogen 2 (osteonidogen)	14095	0.2
chr6_34351591_34352138	0.55	NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	8587	0.19
chr2_40600387_40600603	0.54	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	56925	0.16
chr12_131357170_131358364	0.54	RAN	RAN, member RAS oncogene family	1126	0.44
chr18_415564_415715	0.54	RP11-720L2.2		8777	0.25
chr1_110922648_110923109	0.54	SLC16A4	solute carrier family 16, member 4	1073	0.36
chr2_128395165_128395808	0.54	LIMS2	LIM and senescent cell antigen-like domains 2	4220	0.16
chr7_24957612_24957858	0.54	OSBPL3	oxysterol binding protein-like 3	23	0.98
chr8_131350704_131350855	0.53	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	2404	0.44
chr13_75345669_75345820	0.53	ENSG00000206812	.	337980	0.01
chr9_116318939_116319366	0.53	RGS3	regulator of G-protein signaling 3	8209	0.23
chr15_34153076_34153227	0.53	RP11-3D4.2		3875	0.25
chr4_77865038_77865189	0.53	SEPT11	septin 11	5743	0.25
chr9_79432035_79432186	0.53	PCA3	prostate cancer antigen 3 (non-protein coding)	52758	0.16
chr18_46327589_46327944	0.53	RP11-484L8.1		33375	0.2
chr20_10629664_10629815	0.53	JAG1	jagged 1	13415	0.24
chr15_67399531_67400126	0.53	SMAD3	SMAD family member 3	8811	0.25
chr14_94432076_94432227	0.53	ASB2	ankyrin repeat and SOCS box containing 2	8278	0.16
chr16_87889321_87889990	0.53	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5	7590	0.18
chr14_101308246_101309004	0.52	ENSG00000214548	.	7020	0.04
chr6_133873714_133873865	0.52	RP3-323P13.2		40923	0.19
chr9_18479738_18479998	0.52	ADAMTSL1	ADAMTS-like 1	5637	0.32
chr6_15206442_15206877	0.52	JARID2	jumonji, AT rich interactive domain 2	39868	0.15
chr2_47086635_47086786	0.52	AC016722.3		6075	0.17
chr6_2103859_2104525	0.52	GMDS	GDP-mannose 4,6-dehydratase	72033	0.13
chr7_104607714_104607865	0.52	ENSG00000251911	.	3945	0.22
chr9_128640336_128640592	0.52	PBX3	pre-B-cell leukemia homeobox 3	12914	0.3
chr8_69666100_69666251	0.52	ENSG00000239184	.	58297	0.16
chr3_99989214_99989365	0.52	TBC1D23	TBC1 domain family, member 23	3253	0.26
chr1_249134690_249135278	0.52	ZNF672	zinc finger protein 672	1631	0.28
chr22_39378384_39379009	0.51	APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	282	0.85
chr3_99036991_99037142	0.51	ENSG00000266030	.	48667	0.19
chr15_42253361_42253691	0.51	EHD4	EH-domain containing 4	11250	0.12
chr14_23583246_23583696	0.51	CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	5354	0.11
chr18_20273154_20273305	0.51	RP11-370A5.1		38299	0.17
chr9_124038362_124038896	0.51	RP11-477J21.6		6379	0.15
chr1_16466515_16466919	0.51	RP11-276H7.2		14989	0.11
chr10_89310955_89311253	0.51	ENSG00000222192	.	11839	0.22
chr10_24735385_24735597	0.51	KIAA1217	KIAA1217	2871	0.34
chr11_10680453_10681322	0.50	MRVI1	murine retrovirus integration site 1 homolog	6964	0.2
chr2_47025816_47026068	0.50	LINC01118	long intergenic non-protein coding RNA 1118	17880	0.16
chr9_130565627_130566870	0.50	FPGS	folylpolyglutamate synthase	645	0.49
chr5_71476037_71476188	0.50	MAP1B	microtubule-associated protein 1B	657	0.76
chr6_139724147_139724435	0.50	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	28534	0.23
chrX_134462748_134463038	0.50	ZNF75D	zinc finger protein 75D	15119	0.2
chr14_103045626_103045891	0.50	ENSG00000239224	.	3756	0.21
chr7_114583964_114584237	0.50	MDFIC	MyoD family inhibitor domain containing	10176	0.32
chr5_14450759_14450910	0.50	TRIO	trio Rho guanine nucleotide exchange factor	37723	0.22
chr3_29228707_29228858	0.50	RBMS3	RNA binding motif, single stranded interacting protein 3	93691	0.09
chr6_17866546_17866697	0.50	KIF13A	kinesin family member 13A	49190	0.16
chr3_65932088_65932380	0.50	ENSG00000264716	.	5312	0.21
chr5_131794846_131795957	0.49	ENSG00000202533	.	8438	0.13
chr1_212702932_212703083	0.49	ATF3	activating transcription factor 3	35669	0.15
chr1_230849583_230849871	0.49	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	316	0.87
chr9_72736818_72736969	0.49	MAMDC2-AS1	MAMDC2 antisense RNA 1	8117	0.25
chr8_97117053_97117204	0.49	GDF6	growth differentiation factor 6	55892	0.15
chr3_189721675_189721826	0.49	ENSG00000265045	.	109973	0.06
chr19_10242764_10242915	0.49	EIF3G	eukaryotic translation initiation factor 3, subunit G	12261	0.08
chr9_16627752_16627903	0.49	RP11-62F24.1		2153	0.43
chr20_40260750_40261051	0.49	CHD6	chromodomain helicase DNA binding protein 6	13767	0.23
chr7_81255465_81255616	0.49	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	136772	0.05
chr11_32055190_32055341	0.49	RP1-17K7.2		7529	0.17
chr1_76231815_76231966	0.49	RABGGTB	Rab geranylgeranyltransferase, beta subunit	19989	0.11
chr7_23019071_23019222	0.49	FAM126A	family with sequence similarity 126, member A	34547	0.2
chr17_44820432_44820772	0.48	NSF	N-ethylmaleimide-sensitive factor	16680	0.21
chr3_134184264_134184415	0.48	CEP63	centrosomal protein 63kDa	20246	0.16
chr15_35832576_35832727	0.48	DPH6	diphthamine biosynthesis 6	5715	0.34
chr4_53886237_53886388	0.48	RP11-752D24.2		74456	0.11
chr9_4100181_4100332	0.48	RP11-70J12.1		28372	0.21
chr4_47527226_47527524	0.48	AC092597.3		34901	0.16
chr2_33467839_33468340	0.48	LTBP1	latent transforming growth factor beta binding protein 1	640	0.79
chr22_46083253_46083404	0.48	ATXN10	ataxin 10	15649	0.21
chr12_105621836_105621987	0.48	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	1727	0.42
chr14_33232996_33233147	0.48	AKAP6	A kinase (PRKA) anchor protein 6	28014	0.26
chr1_17559878_17560367	0.48	PADI1	peptidyl arginine deiminase, type I	272	0.9
chr1_59594834_59594985	0.47	FGGY	FGGY carbohydrate kinase domain containing	167401	0.04
chr9_140681085_140681236	0.47	ENSG00000207693	.	51711	0.13
chr11_130501333_130501484	0.47	C11orf44	chromosome 11 open reading frame 44	41443	0.21
chr11_88254615_88254766	0.47	GRM5-AS1	GRM5 antisense RNA 1	9774	0.3
chr8_18661932_18662083	0.47	PSD3	pleckstrin and Sec7 domain containing 3	332	0.91
chr16_47764879_47765030	0.47	PHKB	phosphorylase kinase, beta	34571	0.23
chr1_115870179_115870464	0.47	NGF	nerve growth factor (beta polypeptide)	10536	0.26
chr21_17444695_17444846	0.47	ENSG00000252273	.	36941	0.23
chr12_93008867_93009018	0.47	ENSG00000238865	.	70179	0.11
chr11_86527333_86527484	0.47	PRSS23	protease, serine, 23	15823	0.27
chr1_9268088_9268239	0.46	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	26671	0.16
chr10_80916996_80917718	0.46	ZMIZ1	zinc finger, MIZ-type containing 1	88565	0.09
chr15_89659888_89660039	0.46	ENSG00000239151	.	4047	0.21
chr1_95257800_95258262	0.46	SLC44A3	solute carrier family 44, member 3	27867	0.18
chr2_19807324_19807591	0.46	OSR1	odd-skipped related transciption factor 1	249043	0.02
chr1_63578125_63578276	0.46	ENSG00000252259	.	73921	0.12
chr8_121610510_121610731	0.46	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa	152954	0.04
chr1_42652119_42652270	0.46	FOXJ3	forkhead box J3	3286	0.26
chr22_37908037_37908429	0.46	CARD10	caspase recruitment domain family, member 10	15	0.97
chr18_51942431_51942582	0.46	C18orf54	chromosome 18 open reading frame 54	57551	0.14
chr10_49572050_49572337	0.46	MAPK8	mitogen-activated protein kinase 8	37493	0.18
chr3_120158350_120158501	0.46	FSTL1	follistatin-like 1	11413	0.25
chr17_39108643_39108794	0.46	KRT39	keratin 39	14426	0.08
chr9_5586517_5587285	0.46	KIAA1432	KIAA1432	42124	0.16
chr21_28311885_28312036	0.46	ENSG00000266133	.	14320	0.21
chr12_11864478_11864709	0.45	ETV6	ets variant 6	40842	0.2
chr13_60321809_60321960	0.45	DIAPH3-AS1	DIAPH3 antisense RNA 1	265001	0.02
chr2_234119666_234119817	0.45	ATG16L1	autophagy related 16-like 1 (S. cerevisiae)	1044	0.47
chr3_29734806_29734957	0.45	RBMS3-AS2	RBMS3 antisense RNA 2	50581	0.19
chr7_25162320_25162471	0.45	CYCS	cytochrome c, somatic	2473	0.37
chr5_64493902_64494516	0.45	ENSG00000207439	.	75013	0.12
chr15_71335826_71335977	0.45	THSD4	thrombospondin, type I, domain containing 4	53390	0.14
chr4_122068382_122068533	0.45	TNIP3	TNFAIP3 interacting protein 3	5403	0.25
chr6_75893670_75893821	0.45	COL12A1	collagen, type XII, alpha 1	18763	0.23
chr7_132483257_132483408	0.45	AC009518.8		32121	0.17
chr4_119672667_119672818	0.45	SEC24D	SEC24 family member D	7055	0.28
chr1_206593311_206593758	0.45	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	13798	0.17
chr3_63997180_63997471	0.45	RP11-245J9.4		315	0.83
chr5_143397342_143397493	0.45	ENSG00000239390	.	123027	0.06
chr3_10018102_10018700	0.45	EMC3	ER membrane protein complex subunit 3	9965	0.08
chrX_45571748_45571911	0.45	ENSG00000207870	.	33865	0.2
chr2_179250736_179251021	0.45	AC009948.5		27788	0.15
chr8_132854804_132854955	0.45	EFR3A	EFR3 homolog A (S. cerevisiae)	61456	0.16
chr2_102733353_102733504	0.45	IL1R1	interleukin 1 receptor, type I	12399	0.23
chr12_1552792_1552943	0.45	ERC1	ELKS/RAB6-interacting/CAST family member 1	35509	0.16
chr9_72837523_72837792	0.45	ENSG00000222465	.	33991	0.14
chr10_29297172_29297323	0.45	ENSG00000199402	.	133811	0.05
chr8_49466988_49467139	0.45	RP11-770E5.1		2936	0.41
chr17_48718114_48718630	0.44	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	6154	0.13
chr4_55119045_55119196	0.44	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	9378	0.29
chr13_94962022_94962173	0.44	GPC6-AS1	GPC6 antisense RNA 1	121852	0.06
chr2_216395889_216396040	0.44	AC012462.1		94988	0.08
chr17_55950808_55951594	0.44	CUEDC1	CUE domain containing 1	1170	0.47
chr6_2477993_2478144	0.44	ENSG00000266252	.	68199	0.13
chr14_69421781_69422763	0.44	ACTN1	actinin, alpha 1	8007	0.23
chr13_74792422_74792795	0.44	ENSG00000206617	.	70743	0.12
chr2_75798574_75798725	0.44	EVA1A	eva-1 homolog A (C. elegans)	1801	0.32
chr15_36723081_36723232	0.44	C15orf41	chromosome 15 open reading frame 41	148656	0.05
chr3_11611925_11612156	0.44	VGLL4	vestigial like 4 (Drosophila)	1642	0.43
chr8_69921640_69921791	0.44	ENSG00000238808	.	101094	0.09
chr4_125337205_125337356	0.44	ANKRD50	ankyrin repeat domain 50	296607	0.01
chr20_58825387_58825538	0.44	ENSG00000207802	.	58070	0.16
chr7_77826662_77826813	0.44	RP5-1185I7.1		207000	0.03
chr1_179061243_179061625	0.44	TOR3A	torsin family 3, member A	6927	0.23
chr5_135329366_135329517	0.44	TGFBI	transforming growth factor, beta-induced, 68kDa	35143	0.15
chr3_130755834_130755985	0.44	NEK11	NIMA-related kinase 11	7356	0.16
chr5_39501963_39502389	0.44	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	39774	0.22
chr2_47425913_47426195	0.43	CALM2	calmodulin 2 (phosphorylase kinase, delta)	22314	0.19
chr12_14413818_14414239	0.43	ENSG00000251908	.	10753	0.22
chr7_135375346_135375497	0.43	RP11-644N4.1		13864	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	0.7	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3	1.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.3	1.8	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.3	1.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.3	0.8	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.3	0.8	GO:0007132	meiotic metaphase I(GO:0007132)
0.3	1.1	GO:0070141	response to UV-A(GO:0070141)
0.3	1.1	GO:0043589	skin morphogenesis(GO:0043589)
0.3	0.8	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3	1.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.3	0.5	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.3	1.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.3	0.8	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	0.7	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2	0.5	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	0.7	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.2	0.9	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.2	0.5	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.7	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.2	0.9	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.2	0.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.6	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.2	0.6	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.2	1.2	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2	0.4	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.2	1.6	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.2	0.6	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.6	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.2	0.6	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.7	GO:0071731	response to nitric oxide(GO:0071731)
0.2	0.5	GO:0010761	fibroblast migration(GO:0010761)
0.2	0.5	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.2	0.7	GO:0008218	bioluminescence(GO:0008218)
0.2	1.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.4	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2	1.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.2	0.2	GO:1901419	regulation of response to alcohol(GO:1901419)
0.2	0.7	GO:0007386	compartment pattern specification(GO:0007386)
0.2	1.3	GO:0048844	artery morphogenesis(GO:0048844)
0.2	1.5	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.2	0.5	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.2	0.3	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2	3.8	GO:0030199	collagen fibril organization(GO:0030199)
0.2	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.2	0.6	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2	0.5	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.6	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.1	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.1	0.6	GO:0051014	actin filament severing(GO:0051014)
0.1	0.4	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.3	GO:0060900	optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.1	0.5	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.1	GO:0033622	integrin activation(GO:0033622)
0.1	0.4	GO:0010842	retina layer formation(GO:0010842)
0.1	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.1	GO:0022601	menstrual cycle phase(GO:0022601)
0.1	0.6	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.1	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1	0.2	GO:0061213	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.4	GO:0048840	otolith development(GO:0048840)
0.1	1.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.4	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.8	GO:0015871	choline transport(GO:0015871)
0.1	0.3	GO:0002246	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.1	0.1	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.6	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.4	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.3	GO:0021772	olfactory bulb development(GO:0021772)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.3	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.5	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.5	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	1.8	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.1	0.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.4	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.1	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.3	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.3	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.1	0.5	GO:0071320	cellular response to cAMP(GO:0071320)
0.1	0.7	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.1	0.2	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.1	GO:0050942	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.8	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1	0.3	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.5	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.4	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.2	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	0.6	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.1	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1	0.4	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.6	GO:0043277	apoptotic cell clearance(GO:0043277)
0.1	0.8	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.1	0.1	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.9	GO:0015701	bicarbonate transport(GO:0015701)
0.1	1.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.2	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.1	0.1	GO:0072071	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1	0.3	GO:0042574	retinal metabolic process(GO:0042574)
0.1	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.2	GO:0035929	steroid hormone secretion(GO:0035929)
0.1	0.2	GO:0060174	limb bud formation(GO:0060174)
0.1	0.5	GO:0031000	response to caffeine(GO:0031000)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.4	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.2	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.7	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.1	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.3	GO:0015840	urea transport(GO:0015840)
0.1	0.3	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.3	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	0.2	GO:0033194	response to hydroperoxide(GO:0033194)
0.1	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.5	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.1	0.8	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.1	0.3	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.1	0.9	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1	0.1	GO:0072189	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) kidney smooth muscle tissue development(GO:0072194)
0.1	0.2	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.3	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.4	GO:0071305	cellular response to vitamin D(GO:0071305)
0.1	0.7	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1	0.3	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.3	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.1	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.2	GO:0060013	righting reflex(GO:0060013)
0.0	0.7	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.3	GO:0010092	organ induction(GO:0001759) specification of organ identity(GO:0010092)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.3	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.4	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.2	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.0	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.2	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0010225	response to UV-C(GO:0010225)
0.0	0.2	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.5	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.7	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0010224	response to UV-B(GO:0010224)
0.0	0.1	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.6	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.5	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.1	GO:0009750	response to fructose(GO:0009750)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0034372	triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	1.2	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	1.1	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.3	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.0	0.1	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.0	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.1	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.8	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0010898	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.0	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.4	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.0	0.2	GO:0046688	response to copper ion(GO:0046688)
0.0	0.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0051284	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0042033	chemokine biosynthetic process(GO:0042033) chemokine metabolic process(GO:0050755)
0.0	0.1	GO:0042428	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.0	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0060911	cardiac cell fate commitment(GO:0060911)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.1	GO:0009071	serine family amino acid catabolic process(GO:0009071)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.2	GO:0006953	acute-phase response(GO:0006953)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.0	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) positive regulation of hypersensitivity(GO:0002885)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.0	GO:1902742	apoptotic process involved in development(GO:1902742)
0.0	0.1	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.3	1.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	0.8	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	1.4	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2	0.2	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.2	1.4	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.9	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.7	GO:0033268	node of Ranvier(GO:0033268)
0.2	1.9	GO:0098644	complex of collagen trimers(GO:0098644)
0.2	0.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	1.2	GO:0002102	podosome(GO:0002102)
0.1	0.9	GO:0016342	catenin complex(GO:0016342)
0.1	0.6	GO:0042825	TAP complex(GO:0042825)
0.1	0.4	GO:0032449	CBM complex(GO:0032449)
0.1	0.8	GO:0031143	pseudopodium(GO:0031143)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.5	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.2	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.4	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.6	GO:0001527	microfibril(GO:0001527)
0.1	0.5	GO:0005916	fascia adherens(GO:0005916)
0.1	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	4.3	GO:0005604	basement membrane(GO:0005604)
0.1	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	1.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.2	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	7.1	GO:0030016	myofibril(GO:0030016)
0.1	0.7	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.2	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.6	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.5	GO:0008091	spectrin(GO:0008091)
0.1	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.5	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.3	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1	0.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.7	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.0	GO:0005811	lipid particle(GO:0005811)
0.1	10.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.6	GO:0005581	collagen trimer(GO:0005581)
0.1	1.7	GO:0044309	neuron spine(GO:0044309)
0.1	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	2.5	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	1.6	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	1.5	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.8	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0030061	mitochondrial crista(GO:0030061)
0.0	1.4	GO:0045095	keratin filament(GO:0045095)
0.0	1.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.0	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.6	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.4	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.0	GO:0031045	dense core granule(GO:0031045)
0.0	0.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0005912	adherens junction(GO:0005912)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.8	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.4	1.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.4	0.4	GO:0043559	insulin binding(GO:0043559)
0.3	1.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	2.5	GO:0017166	vinculin binding(GO:0017166)
0.3	1.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2	0.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	1.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.2	0.7	GO:0045545	syndecan binding(GO:0045545)
0.2	0.7	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	0.9	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	0.7	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	1.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	2.7	GO:0005523	tropomyosin binding(GO:0005523)
0.2	0.6	GO:0046980	tapasin binding(GO:0046980)
0.2	0.6	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	1.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2	0.8	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	6.1	GO:0005518	collagen binding(GO:0005518)
0.2	0.5	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.6	GO:0042805	actinin binding(GO:0042805)
0.1	0.4	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	3.0	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.4	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.7	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	1.0	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.5	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.4	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.7	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.7	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.8	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.6	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.0	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.6	GO:0046790	virion binding(GO:0046790)
0.1	1.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.3	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	1.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.2	GO:0034584	piRNA binding(GO:0034584)
0.1	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.8	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.9	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.3	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.5	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.6	GO:0005123	death receptor binding(GO:0005123)
0.1	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.1	4.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	1.0	GO:0045296	cadherin binding(GO:0045296)
0.1	0.3	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.3	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.1	0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.1	0.2	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1	0.5	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	1.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.2	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.5	GO:0005112	Notch binding(GO:0005112)
0.1	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.3	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.3	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.3	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.5	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.3	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0032052	bile acid binding(GO:0032052)
0.0	0.3	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.7	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.6	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.3	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	1.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.8	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	1.4	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.2	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	2.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	1.0	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.4	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	1.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.0	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.0	GO:0009374	biotin binding(GO:0009374)
0.0	0.0	GO:0022839	calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.2	3.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	6.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	0.3	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	2.3	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	1.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	2.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	10.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	1.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.6	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.8	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	5.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	0.4	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.2	2.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	7.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.8	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.9	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	Genes involved in Cytokine Signaling in Immune system
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.1	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.0	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression