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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for NHLH1

Z-value: 2.02

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Transcription factors associated with NHLH1

Gene Symbol	Gene ID	Gene Info
NHLH1 Ensembl NCBI GeneCards UniProt	ENSG00000171786.5	nescient helix-loop-helix 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_160338361_160338512	NHLH1	1579	0.257952	-0.64	6.6e-02	Click!
chr1_160345273_160345443	NHLH1	8501	0.116475	0.38	3.1e-01	Click!
chr1_160337227_160337378	NHLH1	445	0.726536	-0.23	5.5e-01	Click!
chr1_160345035_160345186	NHLH1	8253	0.116942	-0.19	6.3e-01	Click!
chr1_160337858_160338009	NHLH1	1076	0.374496	-0.13	7.4e-01	Click!

Activity of the NHLH1 motif across conditions

Conditions sorted by the z-value of the NHLH1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_1092379_1092530	1.72	IDI1	isopentenyl-diphosphate delta isomerase 1	1883	0.22
chr10_1092925_1093076	1.45	IDI1	isopentenyl-diphosphate delta isomerase 1	1337	0.3
chr12_13056574_13056725	1.44	GPRC5A	G protein-coupled receptor, family C, group 5, member A	5354	0.15
chr6_118886771_118886922	1.03	PLN	phospholamban	17385	0.28
chr22_37822183_37822365	0.92	RP1-63G5.5		1206	0.31
chr15_75091800_75092051	0.89	CSK	c-src tyrosine kinase	1670	0.24
chr17_14201024_14201196	0.89	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	3290	0.33
chr1_152082496_152082664	0.81	TCHH	trichohyalin	3976	0.16
chr8_141108803_141109134	0.79	C8orf17	chromosome 8 open reading frame 17	165552	0.04
chr6_1637395_1637546	0.79	FOXC1	forkhead box C1	26789	0.26
chr7_43593656_43593954	0.78	ENSG00000252308	.	24682	0.15
chr14_93673945_93674143	0.77	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	405	0.58
chr4_7043959_7044306	0.77	TADA2B	transcriptional adaptor 2B	506	0.46
chr5_95067766_95067978	0.77	CTD-2154I11.2		119	0.93
chr10_102988228_102988379	0.76	LBX1-AS1	LBX1 antisense RNA 1 (head to head)	1048	0.37
chr2_9893455_9893842	0.76	ENSG00000200034	.	12736	0.24
chr9_116859598_116859749	0.76	KIF12	kinesin family member 12	1664	0.4
chr19_8275558_8275709	0.75	CERS4	ceramide synthase 4	1115	0.46
chr19_4009920_4010213	0.74	PIAS4	protein inhibitor of activated STAT, 4	2422	0.17
chr4_144435798_144435959	0.74	SMARCA5-AS1	SMARCA5 antisense RNA 1	90	0.96
chr10_118501252_118501433	0.73	HSPA12A	heat shock 70kDa protein 12A	743	0.71
chr10_104253750_104253901	0.73	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	8610	0.1
chr2_20291725_20291876	0.73	RP11-644K8.1		39905	0.13
chr1_2461386_2461569	0.73	HES5	hes family bHLH transcription factor 5	207	0.87
chr2_75426550_75426809	0.72	TACR1	tachykinin receptor 1	147	0.97
chr22_46469795_46469946	0.71	RP6-109B7.4		4099	0.12
chr19_1843050_1843201	0.69	REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	5327	0.09
chr2_71296245_71296452	0.67	NAGK	N-acetylglucosamine kinase	556	0.62
chr20_32265943_32266094	0.66	RP1-63M2.5		3695	0.12
chr9_117880715_117880866	0.66	TNC	tenascin C	254	0.95
chr20_52789945_52790209	0.65	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	111	0.98
chr22_50453000_50453188	0.65	IL17REL	interleukin 17 receptor E-like	2006	0.3
chrX_153713326_153713477	0.64	UBL4A	ubiquitin-like 4A	1553	0.16
chr16_31076495_31076764	0.63	AC135050.5		187	0.51
chr1_155293264_155293415	0.62	RUSC1	RUN and SH3 domain containing 1	389	0.54
chr6_99796927_99797078	0.62	FAXC	failed axon connections homolog (Drosophila)	529	0.8
chr3_134369794_134369945	0.62	KY	kyphoscoliosis peptidase	5	0.98
chr14_74219471_74219668	0.62	ELMSAN1	ELM2 and Myb/SANT-like domain containing 1	2150	0.2
chrX_153187210_153187639	0.60	ARHGAP4	Rho GTPase activating protein 4	202	0.87
chr14_64855283_64855519	0.59	MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	44	0.97
chr9_136996353_136996504	0.58	WDR5	WD repeat domain 5	4059	0.19
chr17_1618281_1618614	0.57	ENSG00000186594	.	1162	0.26
chr2_171568724_171569013	0.56	LINC01124	long intergenic non-protein coding RNA 1124	2209	0.25
chr20_60892338_60892489	0.56	RP11-157P1.4		11032	0.12
chr17_75405439_75405590	0.56	SEPT9	septin 9	4355	0.18
chr13_99190204_99190457	0.55	STK24	serine/threonine kinase 24	16078	0.21
chr10_99330916_99331067	0.55	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	1207	0.35
chr6_170501516_170501667	0.55	RP11-302L19.1		23850	0.21
chr20_62368346_62368508	0.55	LIME1	Lck interacting transmembrane adaptor 1	210	0.82
chr9_69200070_69200221	0.55	FOXD4L6	forkhead box D4-like 6	2059	0.33
chr8_128578287_128578438	0.54	CASC8	cancer susceptibility candidate 8 (non-protein coding)	83978	0.1
chr12_7023886_7024037	0.54	ENO2	enolase 2 (gamma, neuronal)	187	0.83
chr22_46749204_46749355	0.53	TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	17460	0.19
chr5_114515440_114515819	0.53	TRIM36	tripartite motif containing 36	105	0.97
chr3_13689840_13689991	0.53	LINC00620	long intergenic non-protein coding RNA 620	2281	0.32
chr6_7480281_7480507	0.53	RP3-512B11.3		61177	0.11
chr15_79382016_79382167	0.53	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	1015	0.58
chr2_217236096_217236247	0.53	MARCH4	membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase	579	0.72
chr15_45404777_45405065	0.53	DUOX2	dual oxidase 2	1438	0.22
chr2_85981049_85981200	0.53	ATOH8	atonal homolog 8 (Drosophila)	107	0.96
chr13_46785669_46785900	0.52	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	222	0.58
chr10_135207995_135208177	0.52	MTG1	mitochondrial ribosome-associated GTPase 1	408	0.68
chr9_140603655_140603806	0.51	EHMT1	euchromatic histone-lysine N-methyltransferase 1	90276	0.06
chr15_75055139_75055425	0.51	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	14097	0.11
chr7_2934236_2934522	0.51	CARD11	caspase recruitment domain family, member 11	35315	0.16
chr7_44298814_44299210	0.51	CAMK2B	calcium/calmodulin-dependent protein kinase II beta	17107	0.18
chr11_65547712_65547863	0.50	AP5B1	adaptor-related protein complex 5, beta 1 subunit	486	0.64
chr2_227663405_227663664	0.50	IRS1	insulin receptor substrate 1	941	0.59
chr4_184366389_184366540	0.50	CDKN2AIP	CDKN2A interacting protein	614	0.74
chr8_22435704_22435855	0.50	PDLIM2	PDZ and LIM domain 2 (mystique)	13	0.95
chr5_175956210_175956448	0.49	RNF44	ring finger protein 44	1317	0.33
chr12_122711285_122711532	0.49	DIABLO	diablo, IAP-binding mitochondrial protein	560	0.71
chr9_70919268_70919419	0.49	FOXD4L3	forkhead box D4-like 3	2067	0.3
chr21_43188700_43188972	0.48	RIPK4	receptor-interacting serine-threonine kinase 4	1570	0.38
chr17_74490286_74490437	0.48	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	1077	0.35
chr4_6473180_6473331	0.48	PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	918	0.69
chr12_131694167_131694318	0.48	AC092850.1	Protein LOC100996701	85825	0.09
chr19_49631496_49631723	0.48	PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	478	0.61
chr19_38894202_38894438	0.48	FAM98C	family with sequence similarity 98, member C	511	0.6
chr22_47172138_47172381	0.48	TBC1D22A	TBC1 domain family, member 22A	2435	0.29
chr2_219744767_219744998	0.47	WNT10A	wingless-type MMTV integration site family, member 10A	203	0.9
chr2_225906606_225906766	0.47	DOCK10	dedicator of cytokinesis 10	473	0.87
chr1_152080340_152080491	0.47	TCHH	trichohyalin	6141	0.14
chr2_86116759_86116995	0.47	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	740	0.7
chr3_138047519_138047674	0.47	NME9	NME/NM23 family member 9	609	0.76
chr16_67433913_67434064	0.46	ZDHHC1	zinc finger, DHHC-type containing 1	906	0.4
chr10_126107806_126108079	0.46	OAT	ornithine aminotransferase	397	0.86
chr9_126784934_126785085	0.46	LHX2	LIM homeobox 2	7333	0.16
chr3_73673662_73673813	0.46	PDZRN3	PDZ domain containing ring finger 3	254	0.87
chr19_6532607_6533025	0.46	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	1806	0.22
chr5_785429_785580	0.45	ZDHHC11B	zinc finger, DHHC-type containing 11B	18437	0.18
chr11_44338062_44338297	0.45	ALX4	ALX homeobox 4	6463	0.31
chr1_43411697_43412100	0.45	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	12602	0.18
chr2_175191190_175191341	0.45	SP9	Sp9 transcription factor	8409	0.17
chr14_103851126_103851420	0.45	MARK3	MAP/microtubule affinity-regulating kinase 3	456	0.8
chr11_12201089_12201240	0.44	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2	17461	0.24
chr11_67381961_67382202	0.44	NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	6384	0.1
chr10_71181914_71182087	0.44	TACR2	tachykinin receptor 2	5377	0.22
chr17_74099339_74099490	0.44	EXOC7	exocyst complex component 7	63	0.95
chr15_41062480_41062728	0.44	C15orf62	chromosome 15 open reading frame 62	445	0.7
chr13_96362269_96362420	0.44	ENSG00000251901	.	4688	0.26
chr19_58011538_58011761	0.44	ZNF773	zinc finger protein 773	340	0.76
chr16_1992058_1992309	0.44	MSRB1	methionine sulfoxide reductase B1	941	0.25
chr11_125495165_125495407	0.44	CHEK1	checkpoint kinase 1	250	0.89
chr16_837155_837377	0.44	RPUSD1	RNA pseudouridylate synthase domain containing 1	203	0.77
chr10_23003062_23003213	0.44	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	100	0.98
chr3_12990664_12990951	0.44	IQSEC1	IQ motif and Sec7 domain 1	18361	0.22
chr2_71356997_71357205	0.44	MCEE	methylmalonyl CoA epimerase	243	0.59
chr1_6514566_6514743	0.43	ESPN	espin	2936	0.15
chr2_101398154_101398305	0.43	NPAS2	neuronal PAS domain protein 2	38385	0.17
chr14_23447277_23447428	0.43	AJUBA	ajuba LIM protein	406	0.65
chr11_126236112_126236292	0.42	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	10333	0.16
chr10_104161420_104161571	0.42	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	6032	0.12
chr7_99764513_99764874	0.42	GAL3ST4	galactose-3-O-sulfotransferase 4	160	0.86
chr3_52099849_52100000	0.42	LINC00696	long intergenic non-protein coding RNA 696	2357	0.21
chr12_112195610_112195963	0.42	RP11-162P23.2		4092	0.21
chr10_135087408_135087559	0.42	ADAM8	ADAM metallopeptidase domain 8	2871	0.14
chr9_86755543_86755896	0.42	RP11-380F14.2		137415	0.04
chr9_135038470_135038621	0.42	NTNG2	netrin G2	1211	0.56
chr8_145045518_145045669	0.42	PLEC	plectin	2104	0.17
chr14_69620653_69620831	0.41	DCAF5	DDB1 and CUL4 associated factor 5	899	0.6
chr16_90037971_90038485	0.41	CENPBD1	CENPB DNA-binding domains containing 1	714	0.49
chr3_194040445_194040596	0.41	CPN2	carboxypeptidase N, polypeptide 2	31527	0.16
chr9_138797318_138797601	0.41	CAMSAP1	calmodulin regulated spectrin-associated protein 1	1611	0.34
chr19_35609963_35610114	0.41	FXYD3	FXYD domain containing ion transport regulator 3	229	0.85
chr3_182698609_182698760	0.41	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1	253	0.93
chr16_89988399_89988781	0.41	TUBB3	Tubulin beta-3 chain	266	0.65
chr9_116643_116845	0.40	FOXD4	forkhead box D4	1673	0.4
chr16_85646315_85646638	0.40	GSE1	Gse1 coiled-coil protein	287	0.92
chr9_108320085_108320236	0.40	RP11-235C23.5		150	0.64
chr16_1202170_1202361	0.40	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	976	0.4
chr9_132628824_132629005	0.40	USP20	ubiquitin specific peptidase 20	31157	0.12
chr6_2825832_2826072	0.40	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	16142	0.17
chr17_3868599_3869062	0.40	ATP2A3	ATPase, Ca++ transporting, ubiquitous	1094	0.51
chr21_43674893_43675044	0.40	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	1226	0.44
chr6_3259629_3259801	0.40	PSMG4	proteasome (prosome, macropain) assembly chaperone 4	421	0.84
chr2_233186649_233186800	0.40	DIS3L2	DIS3 mitotic control homolog (S. cerevisiae)-like 2	11929	0.18
chr16_57075682_57076072	0.40	NLRC5	NLR family, CARD domain containing 5	15086	0.13
chr9_95797713_95798001	0.40	FGD3	FYVE, RhoGEF and PH domain containing 3	20515	0.16
chr21_44816601_44816752	0.40	SIK1	salt-inducible kinase 1	30332	0.23
chr5_80319496_80319647	0.40	CTC-459I6.1		62845	0.12
chr7_2549413_2549701	0.40	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	2606	0.23
chr1_36807375_36807526	0.39	EVA1B	eva-1 homolog B (C. elegans)	17695	0.12
chr1_92951184_92951335	0.39	GFI1	growth factor independent 1 transcription repressor	369	0.91
chr5_107006960_107007206	0.39	EFNA5	ephrin-A5	487	0.88
chr7_150693553_150693746	0.39	NOS3	nitric oxide synthase 3 (endothelial cell)	2757	0.16
chr9_131581170_131581321	0.39	ENDOG	endonuclease G	492	0.68
chr17_4379761_4380035	0.39	RP13-580F15.2		6981	0.14
chr1_17534291_17534535	0.39	PADI1	peptidyl arginine deiminase, type I	2792	0.25
chr3_20122556_20122752	0.39	KAT2B	K(lysine) acetyltransferase 2B	41139	0.13
chr7_150685880_150686039	0.39	NOS3	nitric oxide synthase 3 (endothelial cell)	2124	0.2
chr19_13616625_13616776	0.39	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	338	0.92
chr17_78833010_78833161	0.39	RP11-28G8.1		53653	0.1
chr17_4070993_4071144	0.39	RP11-810M2.2		3864	0.14
chr1_205414124_205414275	0.39	ENSG00000199059	.	3327	0.21
chr17_76109018_76109228	0.38	ENSG00000204282	.	1243	0.34
chr8_8749966_8750117	0.38	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	1114	0.5
chrX_40132487_40132783	0.38	ENSG00000238920	.	11714	0.29
chr15_81048294_81048445	0.38	KIAA1199	KIAA1199	23315	0.19
chr10_118032962_118033113	0.38	GFRA1	GDNF family receptor alpha 1	58	0.98
chr8_141634428_141634717	0.38	AGO2	argonaute RISC catalytic component 2	11073	0.23
chr1_112281223_112281374	0.38	FAM212B	family with sequence similarity 212, member B	577	0.62
chr12_862525_862676	0.38	WNK1	WNK lysine deficient protein kinase 1	132	0.97
chr1_10694881_10695050	0.38	RP4-734G22.3		4333	0.2
chr11_613104_613469	0.38	IRF7	interferon regulatory factor 7	2340	0.13
chr3_44690178_44690339	0.38	ZNF35	zinc finger protein 35	21	0.97
chr3_134090113_134090264	0.37	AMOTL2	angiomotin like 2	566	0.79
chr9_16871630_16871863	0.37	BNC2	basonuclin 2	905	0.73
chr17_79065167_79065318	0.37	BAIAP2	BAI1-associated protein 2	4981	0.13
chr19_13124274_13124431	0.37	CTC-239J10.1		973	0.31
chr6_3455345_3455496	0.37	SLC22A23	solute carrier family 22, member 23	857	0.73
chr14_69286868_69287190	0.37	ZFP36L1	ZFP36 ring finger protein-like 1	23839	0.18
chr7_101524016_101524398	0.37	CTA-339C12.1		56198	0.12
chr10_12647802_12648097	0.37	ENSG00000263584	.	27197	0.23
chr14_105144169_105144320	0.37	ENSG00000265291	.	158	0.94
chr8_124194815_124194966	0.37	FAM83A	family with sequence similarity 83, member A	31	0.62
chr16_74763993_74764147	0.37	FA2H	fatty acid 2-hydroxylase	11097	0.18
chr20_60925673_60925824	0.37	RP11-157P1.5		2303	0.19
chr1_145435544_145435832	0.37	TXNIP	thioredoxin interacting protein	2781	0.17
chr19_7939419_7939570	0.37	CTD-3193O13.9	Protein FLJ22184	168	0.87
chr19_663634_663908	0.37	RNF126	ring finger protein 126	494	0.63
chr12_52220613_52220764	0.37	AC068987.1	HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881	16899	0.2
chr3_139394252_139394403	0.37	NMNAT3	nicotinamide nucleotide adenylyltransferase 3	2233	0.37
chr12_132627237_132627421	0.37	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	1551	0.3
chr17_7893390_7893541	0.36	GUCY2D	guanylate cyclase 2D, membrane (retina-specific)	12447	0.1
chr6_428112_428263	0.36	IRF4	interferon regulatory factor 4	36448	0.21
chr19_59070081_59070232	0.36	UBE2M	ubiquitin-conjugating enzyme E2M	165	0.67
chr16_88701800_88701951	0.36	IL17C	interleukin 17C	3126	0.13
chr1_99729991_99730185	0.36	LPPR4	Lipid phosphate phosphatase-related protein type 4	240	0.96
chr5_176857919_176858519	0.36	GRK6	G protein-coupled receptor kinase 6	4364	0.11
chr6_5787499_5787650	0.36	RP1-256G22.2		92069	0.09
chr2_190626071_190626222	0.36	OSGEPL1-AS1	OSGEPL1 antisense RNA 1	1284	0.24
chr1_159915900_159916142	0.36	IGSF9	immunoglobulin superfamily, member 9	635	0.57
chr18_56435798_56436090	0.36	RP11-126O1.4		15982	0.15
chr15_73067195_73067414	0.36	ADPGK-AS1	ADPGK antisense RNA 1	7872	0.19
chr16_11889035_11889325	0.35	ZC3H7A	zinc finger CCCH-type containing 7A	1203	0.42
chr11_9336490_9336651	0.35	TMEM41B	transmembrane protein 41B	243	0.93
chr11_6341333_6341484	0.35	PRKCDBP	protein kinase C, delta binding protein	354	0.85
chr2_43341562_43341713	0.35	ENSG00000207087	.	23005	0.25
chr1_114695266_114695421	0.35	SYT6	synaptotagmin VI	196	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0010193	response to ozone(GO:0010193)
0.2	0.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2	1.2	GO:0016114	terpenoid biosynthetic process(GO:0016114)
0.2	0.4	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2	0.5	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.1	0.6	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.4	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.4	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.1	0.4	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.3	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.1	0.2	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.3	GO:0043276	anoikis(GO:0043276)
0.1	0.4	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.4	GO:0017085	response to insecticide(GO:0017085)
0.1	0.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.1	0.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.6	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0051608	histamine transport(GO:0051608)
0.1	0.2	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.2	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1	0.1	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1	0.2	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.1	0.5	GO:0006547	histidine metabolic process(GO:0006547)
0.1	0.5	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.1	0.2	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.2	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.1	0.2	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.5	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.3	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.1	0.1	GO:0051446	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.1	0.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.4	GO:0014888	striated muscle adaptation(GO:0014888)
0.1	0.3	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.1	0.1	GO:0014805	smooth muscle adaptation(GO:0014805)
0.1	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	1.0	GO:0007340	acrosome reaction(GO:0007340)
0.1	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.5	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.3	GO:0015802	basic amino acid transport(GO:0015802)
0.1	0.3	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.2	GO:0019532	oxalate transport(GO:0019532)
0.1	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.2	GO:0060539	diaphragm development(GO:0060539)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.4	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.2	GO:0045006	DNA deamination(GO:0045006)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.3	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.3	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.2	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.3	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.5	GO:0038061	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.2	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.6	GO:0048536	spleen development(GO:0048536)
0.0	0.3	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.4	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0	0.2	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.3	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.4	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.3	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.5	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.4	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0048741	skeletal muscle fiber development(GO:0048741)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.5	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.2	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.2	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.5	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0001554	luteolysis(GO:0001554)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:2000193	regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310) positive regulation of fatty acid transport(GO:2000193)
0.0	0.0	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.2	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0033235	regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0043471	regulation of carbohydrate catabolic process(GO:0043470) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0051187	cofactor catabolic process(GO:0051187)
0.0	0.2	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.2	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.2	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.8	GO:0006096	glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.7	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.1	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0051497	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.0	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.2	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.0	0.0	GO:0042532	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.0	GO:0016199	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.3	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.2	GO:0015893	drug transport(GO:0015893)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.3	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.2	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.0	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.2	GO:0006595	polyamine metabolic process(GO:0006595)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.5	GO:0006754	ATP biosynthetic process(GO:0006754)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.5	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0032329	serine transport(GO:0032329)
0.0	0.0	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0001652	granular component(GO:0001652)
0.1	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.5	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.6	GO:0005883	neurofilament(GO:0005883)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0005827	polar microtubule(GO:0005827)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.2	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.5	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.5	GO:0030914	STAGA complex(GO:0030914)
0.0	0.4	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.4	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.6	GO:0043204	perikaryon(GO:0043204)
0.0	0.0	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.3	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.9	GO:0031674	I band(GO:0031674)
0.0	0.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.7	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.4	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.5	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0042641	actomyosin(GO:0042641)
0.0	0.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.3	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	1.1	GO:0005925	focal adhesion(GO:0005925)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.6	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.0	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0000792	heterochromatin(GO:0000792)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0004995	tachykinin receptor activity(GO:0004995)
0.2	0.7	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.2	0.6	GO:0045545	syndecan binding(GO:0045545)
0.2	0.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.5	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.3	GO:0005113	patched binding(GO:0005113)
0.1	1.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	0.2	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	0.2	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.3	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.4	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.5	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.3	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.3	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.4	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.5	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.6	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.3	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.4	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.7	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.5	GO:0032934	sterol binding(GO:0032934)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.3	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.2	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	1.8	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.3	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.8	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.4	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.3	GO:0034061	DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.0	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.0	0.0	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.9	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.7	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.5	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.5	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.5	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.0	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.3	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes

Results for NHLH1

Z-value: 2.02

Motif logo

Transcription factors associated with NHLH1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the NHLH1 motif across conditions

Conditions sorted by the z-value of the NHLH1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: